TreeWAS – Variant ID: rs10800713

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H52.1 Myopia	0.026	0.974	0.000
I42.0 Dilated cardiomyopathy	0.026	0.974	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.024	0.976	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.023	0.977	0.000
H52 Disorders of refraction and accommodation	0.022	0.978	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.022	0.978	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.021	0.979	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.021	0.979	0.000
H52.3 Anisometropia and aniseikonia	0.020	0.980	0.000
H52.2 Astigmatism	0.020	0.980	0.000
I42.9 Cardiomyopathy, unspecified	0.020	0.980	0.000
I42 Cardiomyopathy	0.019	0.981	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.019	0.981	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.019	0.981	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.018	0.982	0.000
I42.8 Other cardiomyopathies	0.018	0.982	0.000
Z92.6 Personal history of chemotherapy for neoplastic disease	0.000	0.982	0.018
L29.0 Pruritus ani	0.000	0.983	0.017
H52.7 Disorder of refraction, unspecified	0.017	0.983	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.017	0.983	0.000
H52.6 Other disorders of refraction	0.016	0.984	0.000
H52.5 Disorders of accommodation	0.016	0.984	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.016	0.984	0.000
H52.4 Presbyopia	0.016	0.984	0.000
H52.0 Hypermetropia	0.016	0.984	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.014	0.986	0.000
M65 Synovitis and tenosynovitis	0.014	0.986	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.014	0.986	0.000
I42.2 Other hypertrophic cardiomyopathy	0.013	0.986	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.987	0.013
I42.4 Endocardial fibroelastosis	0.013	0.987	0.000
I42.5 Other restrictive cardiomyopathy	0.013	0.987	0.000
M65.3 Trigger finger	0.013	0.987	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.012	0.988	0.000
M65.34 Trigger finger-Hand	0.012	0.988	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.011	0.988	0.000
D33.3 Cranial nerves	0.000	0.988	0.011
T50.1 Loop [high-ceiling] diuretics	0.011	0.989	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.011	0.989	0.000
L29 Pruritus	0.000	0.989	0.011
T50.7 Analeptics and opioid receptor antagonists	0.010	0.989	0.000
T50.5 Appetite depressants	0.010	0.989	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.010	0.989	0.000
T50.0 Mineralocorticoids and their antagonists	0.010	0.989	0.000
D23.7 Skin of lower limb, including hip	0.010	0.990	0.000
T50.8 Diagnostic agents	0.010	0.990	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.010	0.990	0.000
M65.2 Calcific tendinitis	0.010	0.990	0.000
M65.0 Abscess of tendon sheath	0.010	0.990	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.010	0.990	0.000
M65-M68 Disorders of synovium and tendon	0.010	0.990	0.000
T50.4 Drugs affecting uric acid metabolism	0.010	0.990	0.000
L29.2 Pruritus vulvae	0.000	0.990	0.010
M65.1 Other infective (teno)synovitis	0.009	0.990	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.000	0.990	0.010
M66 Spontaneous rupture of synovium and tendon	0.010	0.990	0.000
M65.38 Trigger finger-Other	0.009	0.991	0.000
M65.37 Trigger finger-Ankle/foot	0.009	0.991	0.000
M65.36 Trigger finger-Lower leg	0.009	0.991	0.000
M65.35 Trigger finger-Pelvic/thigh	0.009	0.991	0.000
M65.33 Trigger finger-Forearm	0.009	0.991	0.000
M65.32 Trigger finger-Upper arm	0.009	0.991	0.000
M65.31 Trigger finger-Shldr region	0.009	0.991	0.000
M65.30 Trigger finger-Mult sites	0.009	0.991	0.000
M65.39 Trigger finger-Site unspec	0.009	0.991	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.009	0.991	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.009	0.991	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.009	0.991	0.000
M66.3 Spontaneous rupture of flexor tendons	0.009	0.991	0.000
T46.1 Calcium-channel blockers	0.009	0.991	0.000
I42.6 Alcoholic cardiomyopathy	0.008	0.991	0.000
M24.02 Loose body in joint (Upper arm)	0.009	0.991	0.000
L29.8 Other pruritus	0.000	0.991	0.009
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.008	0.992	0.000
M66.2 Spontaneous rupture of extensor tendons	0.008	0.992	0.000
L29.9 Pruritus, unspecified	0.000	0.992	0.008
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.008	0.992	0.000
L29.1 Pruritus scroti	0.000	0.992	0.008
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.008	0.992	0.000
K81.9 Cholecystitis, unspecified	0.000	0.992	0.008
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.008	0.992	0.000
X62.9 Unspecified place	0.008	0.992	0.000
M67 Other disorders of synovium and tendon	0.008	0.992	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.992	0.008
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.007	0.992	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
M66.4 Spontaneous rupture of other tendons	0.007	0.992	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.007	0.992	0.000
M65.28 Calcific tendinitis (Other)	0.007	0.992	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.007	0.992	0.000
M65.26 Calcific tendinitis (Lower leg)	0.007	0.992	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.007	0.992	0.000
M65.24 Calcific tendinitis (Hand)	0.007	0.992	0.000
M65.23 Calcific tendinitis (Forearm)	0.007	0.992	0.000
M65.22 Calcific tendinitis (Upper arm)	0.007	0.992	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.007	0.992	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.007	0.992	0.000
M65.08 Abscess of tendon sheath (Other)	0.007	0.992	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.007	0.992	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.007	0.992	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.007	0.992	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.007	0.992	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.007	0.992	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.007	0.992	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.007	0.992	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.007	0.993	0.000
M66.24 Spontaneous rupture of extensor tendons (Hand)	0.007	0.993	0.000
T45.2 Vitamins, not elsewhere classified	0.007	0.993	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.007	0.993	0.000
M65.04 Abscess of tendon sheath (Hand)	0.007	0.993	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.993	0.000
M65.19 Other infective (teno)synovitis (Site unspecified)	0.007	0.993	0.000
M65.18 Other infective (teno)synovitis (Other)	0.007	0.993	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.007	0.993	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.007	0.993	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.007	0.993	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.007	0.993	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.007	0.993	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.007	0.993	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.007	0.993	0.000
M66.1 Rupture of synovium	0.007	0.993	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.007	0.993	0.000
M66.23 Spontaneous rupture of extensor tendons (Forearm)	0.007	0.993	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.007	0.993	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.007	0.993	0.000
M66.5 Spontaneous rupture of unspecified tendon	0.007	0.993	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.007	0.993	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.007	0.993	0.000
T46.7 Peripheral vasodilators	0.007	0.993	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.007	0.993	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.007	0.993	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.007	0.993	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.007	0.993	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.007	0.993	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.007	0.993	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.007	0.993	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.007	0.993	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.007	0.993	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.007	0.993	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.007	0.993	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.007	0.993	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.007	0.993	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.007	0.993	0.000
M66.30 Spontaneous rupture of flexor tendons (Multiple sites)	0.007	0.993	0.000
M67.8 Other specified disorders of synovium and tendon	0.007	0.993	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.993	0.007
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.006	0.993	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.993	0.000
R25.2 Cramp and spasm	0.007	0.993	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.007	0.993	0.000
I47.2 Ventricular tachycardia	0.007	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.007	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.993	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.993	0.007
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.006	0.994	0.000
M65.8 Other synovitis and tenosynovitis	0.006	0.994	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.994	0.006
T45.4 Iron and its compounds	0.006	0.994	0.000
T38.0 Glucocorticoids and synthetic analogues	0.006	0.994	0.000
T40.2 Other opioids	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.994	0.006
M65.14 Other infective (teno)synovitis (Hand)	0.006	0.994	0.000
T38.1 Thyroid hormones and substitutes	0.006	0.994	0.000
M54.12 Radiculopathy (Cervical region)	0.000	0.994	0.006
M66.29 Spontaneous rupture of extensor tendons (Site unspecified)	0.006	0.994	0.000
M66.28 Spontaneous rupture of extensor tendons-Other	0.006	0.994	0.000
M66.26 Spontaneous rupture of extensor tendons (Lower leg)	0.006	0.994	0.000
M66.25 Spontaneous rupture of extensor tendons (Pelvic region and thigh)	0.006	0.994	0.000
M66.22 Spontaneous rupture of extensor tendons (Upper arm)	0.006	0.994	0.000
M66.21 Spontaneous rupture of extensor tendons (Shoulder region)	0.006	0.994	0.000
M66.20 Spontaneous rupture of extensor tendons (Multiple sites)	0.006	0.994	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.006	0.994	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.006	0.994	0.000
T38.5 Other oestrogens and progestogens	0.006	0.994	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.006	0.994	0.000
M67.4 Ganglion	0.006	0.994	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.006	0.994	0.000
M24.0 Loose body in joint	0.006	0.994	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
M66.0 Rupture of popliteal cyst	0.006	0.994	0.000
M67.0 Short Achilles tendon (acquired)	0.006	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.006	0.994	0.000
S32.3 Fracture of ilium	0.000	0.994	0.006
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.006	0.994	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
T38.9 Other and unspecified hormone antagonists	0.006	0.994	0.000
T38.7 Androgens and anabolic congeners	0.006	0.994	0.000
T38.4 Oral contraceptives	0.006	0.994	0.000
T38.2 Antithyroid drugs	0.006	0.994	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
S32.4 Fracture of acetabulum	0.000	0.994	0.006
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.000	0.994	0.006
M66.27 Spontaneous rupture of extensor tendons (Ankle and foot)	0.006	0.994	0.000
S32.30 Fracture of ilium (closed)	0.000	0.994	0.006
M67.9 Disorder of synovium and tendon, unspecified	0.006	0.994	0.000
M67.3 Transient synovitis	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.005	0.994	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.005	0.994	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.005	0.994	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.005	0.994	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.005	0.994	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.005	0.994	0.000
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.994	0.006
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
M68.8 Other disorders of synovium and tendon in diseases classified elsewhere	0.005	0.994	0.000
M68.0 Synovitis and tenosynovitis in bacterial diseases classified elsewhere	0.005	0.994	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.994	0.006
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.994	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.006	0.994	0.000
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.005	0.995	0.000
M24.01 Loose body in joint (Shoulder region)	0.005	0.995	0.000
M66.52 Spontaneous rupture of unspecified tendon (Upper arm)	0.005	0.995	0.000
M66.19 Rupture of synovium (Site unspecified)	0.005	0.995	0.000
M66.18 Rupture of synovium (Other)	0.005	0.995	0.000
M66.17 Rupture of synovium (Ankle and foot)	0.005	0.995	0.000
M66.16 Rupture of synovium (Lower leg)	0.005	0.995	0.000
M66.15 Rupture of synovium (Pelvic region and thigh)	0.005	0.995	0.000
M66.14 Rupture of synovium (Hand)	0.005	0.995	0.000
M66.13 Rupture of synovium (Forearm)	0.005	0.995	0.000
M66.12 Rupture of synovium (Upper arm)	0.005	0.995	0.000
M66.11 Rupture of synovium (Shoulder region)	0.005	0.995	0.000
M66.10 Rupture of synovium (Multiple sites)	0.005	0.995	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.005	0.995	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.000	0.995	0.005
T42.4 Benzodiazepines	0.005	0.995	0.000
S32.1 Fracture of sacrum	0.000	0.995	0.005
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.005	0.995	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.005	0.995	0.000
X63.0 Home	0.005	0.995	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M66.59 Spontaneous rupture of unspecified tendon (Site unspecified)	0.005	0.995	0.000
M66.58 Spontaneous rupture of unspecified tendon (Other)	0.005	0.995	0.000
M66.56 Spontaneous rupture of unspecified tendon (Lower leg)	0.005	0.995	0.000
M66.55 Spontaneous rupture of unspecified tendon (Pelvic region and thigh)	0.005	0.995	0.000
M66.54 Spontaneous rupture of unspecified tendon (Hand)	0.005	0.995	0.000
M66.53 Spontaneous rupture of unspecified tendon (Forearm)	0.005	0.995	0.000
M66.51 Spontaneous rupture of unspecified tendon (Shoulder region)	0.005	0.995	0.000
M66.50 Spontaneous rupture of unspecified tendon (Multiple sites)	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.005	0.995	0.000
M67.47 Ganglion, ankle and foot	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.005	0.995	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.995	0.005
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.995	0.005
T47.2 Stimulant laxatives	0.005	0.995	0.000
M54.1 Radiculopathy	0.000	0.995	0.005
S32.2 Fracture of coccyx	0.000	0.995	0.005
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.005	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.005	0.995	0.000
T47.7 Emetics	0.005	0.995	0.000
T47.5 Digestants	0.005	0.995	0.000
T47.3 Saline and osmotic laxatives	0.005	0.995	0.000
S36 Injury of intra-abdominal organs	0.000	0.995	0.005
T42.1 Iminostilbenes	0.005	0.995	0.000
M24 Other specific joint derangements	0.005	0.995	0.000
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.005	0.995	0.000
M24.2 Disorder of ligament	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.005	0.995	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.005	0.995	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.005	0.995	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.005	0.995	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.005	0.995	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.005	0.995	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.995	0.005
M24.21 Disorder of ligament (Shoulder region)	0.005	0.995	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.005	0.995	0.000
T47.4 Other laxatives	0.005	0.995	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.005	0.995	0.000
M67.43 Ganglion, wrist	0.005	0.995	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.000	0.995	0.005
T40.5 Cocaine	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.005	0.995	0.000
T40.8 Lysergide [LSD]	0.005	0.995	0.000
T40.7 Cannabis (derivatives)	0.005	0.995	0.000
T40.3 Methadone	0.005	0.995	0.000
T40.0 Opium	0.005	0.995	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.995	0.005
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
M67.49 Ganglion, multiple sites	0.005	0.995	0.000
M67.45 Ganglion, hip	0.005	0.995	0.000
I77.1 Stricture of artery	0.000	0.995	0.005
S36.8 Injury of other intra-abdominal organs	0.000	0.995	0.005
M24.09 Loose body in joint (Site unspecified)	0.005	0.995	0.000
M24.08 Loose body in joint (Other)	0.005	0.995	0.000
M24.00 Loose body in joint (Multiple sites)	0.005	0.995	0.000
M54.22 Cervicalgia (Cervical region)	0.000	0.995	0.005
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.004	0.995	0.000
M66.09 Rupture of popliteal cyst-Site unspec	0.004	0.995	0.000
M66.08 Rupture of popliteal cyst-Other	0.004	0.995	0.000
M66.07 Rupture of popliteal cyst-Ankle/foot	0.004	0.995	0.000
M66.05 Rupture of popliteal cyst-Pelvic/thigh	0.004	0.995	0.000
M66.04 Rupture of popliteal cyst-Hand	0.004	0.995	0.000
M66.03 Rupture of popliteal cyst-Forearm	0.004	0.995	0.000
M66.02 Rupture of popliteal cyst-Upper arm	0.004	0.995	0.000
M66.01 Rupture of popliteal cyst-Shldr region	0.004	0.995	0.000
M66.00 Rupture of popliteal cyst-Mult sites	0.004	0.995	0.000
M66.57 Spontaneous rupture of unspecified tendon (Ankle and foot)	0.004	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.995	0.000
T37.5 Antiviral drugs	0.004	0.995	0.000
T37.4 Anthelminthics	0.004	0.995	0.000
T37.3 Other antiprotozoal drugs	0.004	0.995	0.000
T37.1 Antimycobacterial drugs	0.004	0.995	0.000
T37.0 Sulphonamides	0.004	0.995	0.000
S32.31 Fracture of ilium (open)	0.000	0.995	0.004
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.000	0.995	0.005
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.995	0.005
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.000	0.995	0.005
X60-X84 Intentional self-harm	0.005	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.995	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.995	0.005
M24.07 Loose body in joint (Ankle and foot)	0.005	0.995	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.005	0.995	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.005	0.995	0.000
X62.0 Home	0.004	0.995	0.000
X62.7 Farm	0.004	0.995	0.000
X62.6 Industrial and construction area	0.004	0.995	0.000
X62.5 Trade and service area	0.004	0.995	0.000
X62.4 Street and highway	0.004	0.995	0.000
X62.3 Sports and athletics area	0.004	0.995	0.000
X62.2 School, other institution and public administrative area	0.004	0.995	0.000
X62.1 Residential institution	0.004	0.995	0.000
M24.24 Disorder of ligament (Hand)	0.005	0.995	0.000
S32.41 Fracture of acetabulum (open)	0.000	0.995	0.004
T47.0 Histamine H(2)-receptor antagonists	0.004	0.995	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.995	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.995	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.000	0.995	0.004
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.000	0.995	0.004
X62.8 Other specified place	0.004	0.995	0.000
M24.03 Loose body in joint (Forearm)	0.004	0.995	0.000
M67.1 Other contracture of tendon (sheath)	0.004	0.995	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.004	0.995	0.000
T42.3 Barbiturates	0.004	0.995	0.000
L90 Atrophic disorders of skin	0.000	0.995	0.004
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.004	0.996	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
M24.06 Loose body in joint-Lower leg	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
S82.60 Fracture of lateral malleolus (closed)	0.004	0.996	0.000
M24.7 Protrusio acetabuli	0.004	0.996	0.000
T40.1 Heroin	0.004	0.996	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.000	0.996	0.004
S32.10 Fracture of sacrum (closed)	0.000	0.996	0.004
S32.01 Fracture of lumbar vertebra (open)	0.000	0.996	0.004
M24.05 Loose body in joint (Pelvic region and thigh)	0.004	0.996	0.000
Q21.0 Ventricular septal defect	0.004	0.996	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.004	0.996	0.000
S36.1 Injury of liver or gallbladder	0.000	0.996	0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.004	0.996	0.000
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.996	0.004
T36.4 Tetracyclines	0.004	0.996	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.000	0.996	0.004
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.000	0.996	0.004
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.004	0.996	0.000
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.996	0.004
M54.2 Cervicalgia	0.000	0.996	0.004
M54.19 Radiculopathy (Site unspecified)	0.000	0.996	0.004
S32.11 Fracture of sacrum (open)	0.000	0.996	0.004
M24.9 Joint derangement, unspecified	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
M54.14 Radiculopathy (Thoracic region)	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
M24.04 Loose body in joint (Hand)	0.004	0.996	0.000
T43.2 Other and unspecified antidepressants	0.004	0.996	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.000	0.996	0.004
M24.28 Disorder of ligament (Other)	0.004	0.996	0.000
S37 Injury of urinary and pelvic organs	0.000	0.996	0.004
M65.83 Other synovitis and tenosynovitis (Forearm)	0.003	0.996	0.001
M24.75 Protrusio acetabuli-Pelvic/thigh	0.004	0.996	0.000
M54 Dorsalgia	0.000	0.996	0.004
S30 Superficial injury of abdomen, lower back and pelvis	0.000	0.996	0.004
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.004	0.996	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.004	0.996	0.000
S36.0 Injury of spleen	0.000	0.996	0.004
S43.0 Dislocation of shoulder joint	0.004	0.996	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.996	0.004
S34.2 Injury of nerve root of lumbar and sacral spine	0.000	0.996	0.004
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.996	0.004
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.996	0.004
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.996	0.004
S32.21 Fracture of coccyx (open)	0.000	0.996	0.004
S32.20 Fracture of coccyx (closed)	0.000	0.996	0.004
M54.9 Dorsalgia, unspecified	0.000	0.996	0.004
T36.8 Other systemic antibiotics	0.004	0.996	0.000
E11.4 With neurological complications	0.000	0.996	0.004
S36.9 Injury of unspecified intra-abdominal organ	0.000	0.996	0.004
S36.7 Injury of multiple intra-abdominal organs	0.000	0.996	0.004
S36.5 Injury of colon	0.000	0.996	0.004
S36.3 Injury of stomach	0.000	0.996	0.004
S36.2 Injury of pancreas	0.000	0.996	0.004
M24.29 Disorder of ligament (Site unspecified)	0.004	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.004	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.004	0.996	0.000
X83 Intentional self-harm by other specified means	0.004	0.996	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
S36.6 Injury of rectum	0.000	0.996	0.004
T36.3 Macrolides	0.003	0.996	0.000
U80 Agent resistant to penicillin and related antibiotics	0.004	0.996	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.000	0.996	0.004
S30.1 Contusion of abdominal wall	0.000	0.996	0.004
U80.0 Penicillin resistant agent	0.004	0.996	0.000
X63.9 Unspecified place	0.004	0.996	0.000
X63.8 Other specified place	0.004	0.996	0.000
X63.7 Farm	0.004	0.996	0.000
X63.6 Industrial and construction area	0.004	0.996	0.000
X63.5 Trade and service area	0.004	0.996	0.000
X63.4 Street and highway	0.004	0.996	0.000
X63.3 Sports and athletics area	0.004	0.996	0.000
X63.2 School, other institution and public administrative area	0.004	0.996	0.000
X63.1 Residential institution	0.004	0.996	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.004	0.996	0.000
X65 Intentional self-poisoning by and exposure to alcohol	0.004	0.996	0.000
M24.23 Disorder of ligament (Forearm)	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
L90.8 Other atrophic disorders of skin	0.000	0.996	0.004
T42.0 Hydantoin derivatives	0.004	0.996	0.000
M66.06 Rupture of popliteal cyst-Lower leg	0.003	0.996	0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.996	0.004
X61.2 School, other institution and public administrative area	0.004	0.996	0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.004	0.996	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.004	0.996	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.000	0.996	0.003
M54.6 Pain in thoracic spine	0.000	0.996	0.004
U89.8 Agent resistant to other single specified antibiotic	0.004	0.996	0.000
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.996	0.004
S32.5 Fracture of pubis	0.000	0.996	0.004
X70 Intentional self-harm by hanging, strangulation and suffocation	0.004	0.996	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.996	0.003
X61.4 Street and highway	0.003	0.996	0.000
X82 Intentional self-harm by crashing of motor vehicle	0.003	0.996	0.000
X81 Intentional self-harm by jumping or lying before moving object	0.003	0.996	0.000
X80 Intentional self-harm by jumping from a high place	0.003	0.996	0.000
X79 Intentional self-harm by blunt object	0.003	0.996	0.000
X77 Intentional self-harm by steam, hot vapours and hot objects	0.003	0.996	0.000
X76 Intentional self-harm by smoke, fire and flames	0.003	0.996	0.000
X75 Intentional self-harm by explosive material	0.003	0.996	0.000
X74 Intentional self-harm by other and unspecified firearm discharge	0.003	0.996	0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.003	0.996	0.000
X72 Intentional self-harm by handgun discharge	0.003	0.996	0.000
X71 Intentional self-harm by drowning and submersion	0.003	0.996	0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.003	0.996	0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.003	0.996	0.000
S22.01 Fracture of thoracic vertebra (open)	0.000	0.996	0.003
X68 Intentional self-poisoning by and exposure to pesticides	0.003	0.996	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.003	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.003	0.996	0.000
L90.9 Atrophic disorder of skin, unspecified	0.000	0.996	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations