TreeWAS – Variant ID: rs10801727

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I27.0 Primary pulmonary hypertension	0.055	0.945	0.000
I27 Other pulmonary heart diseases	0.044	0.956	0.000
I27.9 Pulmonary heart disease, unspecified	0.040	0.960	0.000
I27.2 Other secondary pulmonary hypertension	0.035	0.965	0.000
O36.8 Maternal care for other specified foetal problems	0.033	0.967	0.000
I27.1 Kyphoscoliotic heart disease	0.032	0.968	0.000
I27.8 Other specified pulmonary heart diseases	0.029	0.971	0.000
O36 Maternal care for other known or suspected foetal problems	0.028	0.972	0.000
O36.5 Maternal care for poor foetal growth	0.027	0.973	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.025	0.975	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.024	0.976	0.000
Q28 Other congenital malformations of circulatory system	0.024	0.976	0.000
Q24 Other congenital malformations of heart	0.024	0.976	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.024	0.976	0.000
O36.2 Maternal care for hydrops foetalis	0.023	0.977	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.023	0.977	0.000
O36.6 Maternal care for excessive foetal growth	0.023	0.977	0.000
Q24.5 Malformation of coronary vessels	0.022	0.978	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.022	0.978	0.000
O36.4 Maternal care for intra-uterine death	0.021	0.978	0.000
Q27 Other congenital malformations of peripheral vascular system	0.022	0.978	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.021	0.979	0.000
Q21 Congenital malformations of cardiac septa	0.021	0.979	0.000
Q25 Congenital malformations of great arteries	0.021	0.979	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.020	0.979	0.000
Q24.6 Congenital heart block	0.020	0.980	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.019	0.980	0.000
Q24.8 Other specified congenital malformations of heart	0.019	0.981	0.000
Q26 Congenital malformations of great veins	0.019	0.981	0.000
Q28.3 Other malformations of cerebral vessels	0.019	0.981	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.018	0.982	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.018	0.982	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.018	0.982	0.000
I28 Other diseases of pulmonary vessels	0.018	0.982	0.000
I26 Pulmonary embolism	0.018	0.982	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.017	0.982	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.017	0.982	0.000
Q28.1 Other malformations of precerebral vessels	0.017	0.982	0.000
Q27.3 Peripheral arteriovenous malformation	0.018	0.982	0.000
Q25.6 Stenosis of pulmonary artery	0.017	0.982	0.000
Q24.4 Congenital subaortic stenosis	0.017	0.982	0.000
Q24.3 Pulmonary infundibular stenosis	0.017	0.982	0.000
Q24.2 Cor triatriatum	0.017	0.982	0.000
Q24.1 Levocardia	0.017	0.982	0.000
Q22.1 Congenital pulmonary valve stenosis	0.017	0.983	0.000
O36.1 Maternal care for other isoimmunisation	0.017	0.983	0.000
Q21.3 Tetralogy of Fallot	0.017	0.983	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.017	0.983	0.000
Q22.5 Ebstein's anomaly	0.017	0.983	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.016	0.984	0.000
Q25.1 Coarctation of aorta	0.016	0.984	0.000
Q25.0 Patent ductus arteriosus	0.016	0.984	0.000
Q21.0 Ventricular septal defect	0.016	0.984	0.000
Q21.8 Other congenital malformations of cardiac septa	0.016	0.984	0.000
Q23 Congenital malformations of aortic and mitral valves	0.016	0.984	0.000
Q27.4 Congenital phlebectasia	0.016	0.984	0.000
Q27.2 Other congenital malformations of renal artery	0.016	0.984	0.000
Q27.1 Congenital renal artery stenosis	0.016	0.984	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.016	0.984	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.015	0.985	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.015	0.985	0.000
Q22.6 Hypoplastic right heart syndrome	0.015	0.985	0.000
Q22.4 Congenital tricuspid stenosis	0.015	0.985	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.015	0.985	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.015	0.985	0.000
Q22.0 Pulmonary valve atresia	0.015	0.985	0.000
Q21.4 Aortopulmonary septal defect	0.015	0.985	0.000
Q21.2 Atrioventricular septal defect	0.015	0.985	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.015	0.985	0.000
Q25.8 Other congenital malformations of great arteries	0.015	0.985	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.015	0.985	0.000
Q25.5 Atresia of pulmonary artery	0.015	0.985	0.000
Q25.2 Atresia of aorta	0.015	0.985	0.000
O36.9 Maternal care for foetal problem, unspecified	0.015	0.985	0.000
Q24.0 Dextrocardia	0.015	0.985	0.000
Q25.3 Stenosis of aorta	0.015	0.985	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.015	0.985	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.014	0.985	0.000
C15.9 Oesophagus, unspecified	0.000	0.986	0.014
I28.0 Arteriovenous fistula of pulmonary vessels	0.014	0.986	0.000
Q25.4 Other congenital malformations of aorta	0.014	0.986	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.014	0.986	0.000
Q26.8 Other congenital malformations of great veins	0.014	0.986	0.000
Q26.6 Portal vein-hepatic artery fistula	0.014	0.986	0.000
Q26.5 Anomalous portal venous connexion	0.014	0.986	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.014	0.986	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.014	0.986	0.000
Q26.1 Persistent left superior vena cava	0.014	0.986	0.000
Q26.0 Congenital stenosis of vena cava	0.014	0.986	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.986	0.014
I28.8 Other specified diseases of pulmonary vessels	0.013	0.987	0.000
Q21.1 Atrial septal defect	0.013	0.987	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.013	0.987	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.013	0.987	0.000
Q20.6 Isomerism of atrial appendages	0.013	0.987	0.000
Q20.5 Discordant atrioventricular connexion	0.013	0.987	0.000
Q20.4 Double inlet ventricle	0.013	0.987	0.000
Q20.3 Discordant ventriculoarterial connexion	0.013	0.987	0.000
Q20.2 Double outlet left ventricle	0.013	0.987	0.000
Q20.1 Double outlet right ventricle	0.013	0.987	0.000
Q20.0 Common arterial trunk	0.013	0.987	0.000
I28.9 Disease of pulmonary vessels, unspecified	0.013	0.987	0.000
I28.1 Aneurysm of pulmonary artery	0.013	0.987	0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.012	0.988	0.000
C15 Malignant neoplasm of oesophagus	0.000	0.988	0.012
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.011	0.988	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.011	0.988	0.000
Q23.4 Hypoplastic left heart syndrome	0.011	0.988	0.000
Q23.3 Congenital mitral insufficiency	0.011	0.988	0.000
Q23.2 Congenital mitral stenosis	0.011	0.988	0.000
C15.4 Middle third of oesophagus	0.000	0.989	0.011
Q23.0 Congenital stenosis of aortic valve	0.011	0.989	0.000
Q23.1 Congenital insufficiency of aortic valve	0.010	0.990	0.000
C15.5 Lower third of oesophagus	0.000	0.990	0.010
C15.8 Overlapping lesion of oesophagus	0.000	0.991	0.008
C15.3 Upper third of oesophagus	0.000	0.991	0.009
C15.2 Abdominal part of oesophagus	0.000	0.991	0.008
C15.0 Cervical part of oesophagus	0.000	0.991	0.008
S06.30 Focal brain injury (without open intracranial wound)	0.008	0.992	0.000
C15.1 Thoracic part of oesophagus	0.000	0.992	0.008
K04.5 Chronic apical periodontitis	0.000	0.993	0.007
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.993	0.007
S83.3 Tear of articular cartilage of knee, current	0.000	0.994	0.006
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.994	0.006
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.994	0.006
C50.1 Central portion of breast	0.000	0.995	0.005
J32.0 Chronic maxillary sinusitis	0.000	0.995	0.005
S83.1 Dislocation of knee	0.000	0.995	0.005
S83.0 Dislocation of patella	0.000	0.995	0.005
M25.57 Pain in joint (Ankle and foot)	0.005	0.995	0.000
S83.7 Injury to multiple structures of knee	0.000	0.995	0.005
S64.4 Injury of digital nerve of other finger	0.000	0.995	0.005
G11.9 Hereditary ataxia, unspecified	0.005	0.995	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.005	0.995	0.000
F60.6 Anxious [avoidant] personality disorder	0.004	0.996	0.000
F60 Specific personality disorders	0.004	0.996	0.000
F60.9 Personality disorder, unspecified	0.004	0.996	0.000
D37.7 Other digestive organs	0.000	0.996	0.004
F60.7 Dependent personality disorder	0.004	0.996	0.000
F60.0 Paranoid personality disorder	0.004	0.996	0.000
K63.2 Fistula of intestine	0.004	0.996	0.000
S06.3 Focal brain injury	0.004	0.996	0.000
J30.3 Other allergic rhinitis	0.000	0.996	0.004
F60.5 Anankastic personality disorder	0.003	0.997	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.000	0.997	0.003
Z39.0 Care and examination immediately after delivery	0.003	0.997	0.000
F60.4 Histrionic personality disorder	0.003	0.997	0.000
F60.1 Schizoid personality disorder	0.003	0.997	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.000	0.997	0.003
F60.3 Emotionally unstable personality disorder	0.003	0.997	0.000
F60.8 Other specific personality disorders	0.003	0.997	0.000
F60.2 Dissocial personality disorder	0.003	0.997	0.000
D25.9 Leiomyoma of uterus, unspecified	0.000	0.997	0.003
J32.1 Chronic frontal sinusitis	0.000	0.997	0.003
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.997	0.003
J32 Chronic sinusitis	0.000	0.997	0.003
J32.4 Chronic pansinusitis	0.000	0.997	0.003
S27.2 Traumatic heamopneumothorax	0.000	0.997	0.003
S27.0 Traumatic pneumothorax	0.000	0.997	0.003
W21.9 Unspecified place	0.000	0.997	0.003
S06.31 Focal brain injury (with open intracranial wound)	0.003	0.997	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.003	0.997	0.000
F61 Mixed and other personality disorders	0.003	0.997	0.000
O64.1 Obstructed labour due to breech presentation	0.003	0.997	0.000
J30.1 Allergic rhinitis due to pollen	0.000	0.997	0.003
S02.40 Fracture of malar and maxillary bones (closed)	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.000	0.997	0.003
F60-F69 Disorders of adult personality and behaviour	0.003	0.997	0.000
F80.1 Expressive language disorder	0.003	0.997	0.000
O61.0 Failed medical induction of labour	0.003	0.997	0.000
S27.3 Other injuries of lung	0.000	0.997	0.002
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
J32.2 Chronic ethmoidal sinusitis	0.000	0.998	0.002
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.8 Injury of other specified intrathoracic organs	0.000	0.998	0.002
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
J30 Vasomotor and allergic rhinitis	0.000	0.998	0.002
E80.4 Gilbert's syndrome	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
K56.5 Intestinal adhesions [bands] with obstruction	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
J30.0 Vasomotor rhinitis	0.000	0.998	0.002
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
O70.2 Third degree perineal laceration during delivery	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.000	0.998	0.002
S27.7 Multiple injuries of intrathoracic organs	0.000	0.998	0.002
S27.6 Injury of pleura	0.000	0.998	0.002
S27.5 Injury of thoracic trachea	0.000	0.998	0.002
S27.4 Injury of bronchus	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
S27.1 Traumatic haemothorax	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.002	0.998	0.000
F68 Other disorders of adult personality and behaviour	0.002	0.998	0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.002	0.998	0.000
F65 Disorders of sexual preference	0.002	0.998	0.000
F63 Habit and impulse disorders	0.002	0.998	0.000
R09.1 Pleurisy	0.002	0.998	0.000
F62 Enduring personality changes, not attributable to brain damage and disease	0.002	0.998	0.000
G11 Hereditary ataxia	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.998	0.002
N90.9 Noninflammatory disorder of vulva and perineum, unspecified	0.000	0.998	0.002
I08.1 Disorders of both mitral and tricuspid valves	0.002	0.998	0.000
F64 Gender identity disorders	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.000	0.998	0.002
H27.0 Aphakia	0.002	0.998	0.000
R07.1 Chest pain on breathing	0.002	0.998	0.000
F31 Bipolar affective disorder	0.000	0.998	0.002
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
O61 Failed induction of labour	0.002	0.998	0.000
J30.2 Other seasonal allergic rhinitis	0.000	0.998	0.002
S81.9 Open wound of lower leg, part unspecified	0.000	0.998	0.002
F69 Unspecified disorder of adult personality and behaviour	0.002	0.998	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.998	0.002
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
J32.9 Chronic sinusitis, unspecified	0.000	0.998	0.002
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.998	0.000
M35.1 Other overlap syndromes	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.000	0.998	0.002
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.000	0.998	0.002
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.000	0.998	0.002
F63.9 Habit and impulse disorder, unspecified	0.002	0.998	0.000
F63.8 Other habit and impulse disorders	0.002	0.998	0.000
F63.3 Trichotillomania	0.002	0.998	0.000
F63.2 Pathological stealing [kleptomania]	0.002	0.998	0.000
F63.1 Pathological fire-setting [pyromania]	0.002	0.998	0.000
F63.0 Pathological gambling	0.002	0.998	0.000
F65.9 Disorder of sexual preference, unspecified	0.002	0.998	0.000
F65.8 Other disorders of sexual preference	0.002	0.998	0.000
F65.6 Multiple disorders of sexual preference	0.002	0.998	0.000
F65.5 Sadomasochism	0.002	0.998	0.000
F65.4 Paedophilia	0.002	0.998	0.000
F65.3 Voyeurism	0.002	0.998	0.000
F65.2 Exhibitionism	0.002	0.998	0.000
F65.1 Fetishistic transvestism	0.002	0.998	0.000
F65.0 Fetishism	0.002	0.998	0.000
F66.9 Psychosexual development disorder, unspecified	0.002	0.998	0.000
F66.8 Other psychosexual development disorders	0.002	0.998	0.000
F66.2 Sexual relationship disorder	0.002	0.998	0.000
F66.1 Egodystonic sexual orientation	0.002	0.998	0.000
F66.0 Sexual maturation disorder	0.002	0.998	0.000
F68.8 Other specified disorders of adult personality and behaviour	0.002	0.998	0.000
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]	0.002	0.998	0.000
F68.0 Elaboration of physical symptoms for psychological reasons	0.002	0.998	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.002	0.998	0.000
D52.9 Folate deficiency anaemia, unspecified	0.002	0.998	0.000
O61.1 Failed instrumental induction of labour	0.002	0.998	0.000
F62.8 Other enduring personality changes	0.002	0.998	0.000
F62.1 Enduring personality change after psychiatric illness	0.002	0.998	0.000
F62.0 Enduring personality change after catastrophic experience	0.002	0.998	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.000	0.998	0.002
G11.8 Other hereditary ataxias	0.002	0.998	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.002	0.998	0.000
G11.2 Late-onset cerebellar ataxia	0.002	0.998	0.000
G11.0 Congenital nonprogressive ataxia	0.002	0.998	0.000
K81.0 Acute cholecystitis	0.002	0.998	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
F62.9 Enduring personality change, unspecified	0.002	0.998	0.000
F64.9 Gender identity disorder, unspecified	0.002	0.998	0.000
F64.8 Other gender identity disorders	0.002	0.998	0.000
F64.2 Gender identity disorder of childhood	0.002	0.998	0.000
F64.1 Dual-role transvestism	0.002	0.998	0.000
O61.9 Failed induction of labour, unspecified	0.002	0.998	0.000
E80.2 Other porphyria	0.002	0.998	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.998	0.000
D36.7 Other specified sites	0.002	0.998	0.000
W84.9 Unspecified place	0.002	0.998	0.000
G11.4 Hereditary spastic paraplegia	0.002	0.998	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
O61.8 Other failed induction of labour	0.002	0.998	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.002	0.998	0.000
Q96.9 Turner's syndrome, unspecified	0.002	0.998	0.000
C18.6 Descending colon	0.000	0.998	0.002
J32.8 Other chronic sinusitis	0.000	0.998	0.002
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.998	0.000
F64.0 Transsexualism	0.001	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.000	0.998	0.002
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
G11.1 Early-onset cerebellar ataxia	0.001	0.998	0.000
O64.5 Obstructed labour due to compound presentation	0.001	0.998	0.000
O64.4 Obstructed labour due to shoulder presentation	0.001	0.998	0.000
O64.3 Obstructed labour due to brow presentation	0.001	0.998	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
O72 Postpartum haemorrhage	0.002	0.998	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.000	0.998	0.002
Q96 Turner's syndrome	0.001	0.998	0.000
F31.8 Other bipolar affective disorders	0.000	0.998	0.001
N75.1 Abscess of Bartholin's gland	0.000	0.998	0.002
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.998	0.001
R09.2 Respiratory arrest	0.002	0.998	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.002	0.998	0.000
K46 Unspecified abdominal hernia	0.000	0.998	0.002
K12.3 Oral mucositis (ulcerative)	0.001	0.998	0.000
O72.0 Third-stage haemorrhage	0.001	0.998	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.001	0.998	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.001	0.999	0.000
E78.8 Other disorders of lipoprotein metabolism	0.001	0.999	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.999	0.001
S81 Open wound of lower leg	0.000	0.999	0.001
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
F80.2 Receptive language disorder	0.001	0.999	0.000
O72.3 Postpartum coagulation defects	0.001	0.999	0.000
Q90 Down's syndrome	0.001	0.999	0.000
Z33 Pregnant state, incidental	0.001	0.999	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
E80.1 Porphyria cutanea tarda	0.001	0.999	0.000
N97.1 Female infertility of tubal origin	0.001	0.999	0.000
Q96.8 Other variants of Turner's syndrome	0.001	0.999	0.000
Q96.4 Mosaicism, 45,X/other cell line(s) with abnormal sex chromosome	0.001	0.999	0.000
Q96.3 Mosaicism, 45,X/46,XX or XY	0.001	0.999	0.000
Q96.2 Karyotype 46,X with abnormal sex chromosome, except iso (Xq)	0.001	0.999	0.000
Q96.1 Karyotype 46,X iso (Xq)	0.001	0.999	0.000
Q96.0 Karyotype 45,X	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.001	0.999	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.001	0.999	0.000
F80.8 Other developmental disorders of speech and language	0.001	0.999	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.001	0.999	0.000
F80.0 Specific speech articulation disorder	0.001	0.999	0.000
J43.2 Centrilobular emphysema	0.000	0.999	0.001
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.001	0.999	0.000
I74.5 Embolism and thrombosis of iliac artery	0.000	0.999	0.001
Q04.8 Other specified congenital malformations of brain	0.001	0.999	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.999	0.001
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.001	0.999	0.000
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
C45.7 Mesothelioma of other sites	0.001	0.999	0.000
E22.0 Acromegaly and pituitary gigantism	0.001	0.999	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.001	0.999	0.000
E80.5 Crigler-Najjar syndrome	0.001	0.999	0.000
E80.3 Defects of catalase and peroxydase	0.001	0.999	0.000
E80.0 Hereditary erythropoietic porphyria	0.001	0.999	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.999	0.001
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.001	0.999	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.001	0.999	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.001	0.999	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.001	0.999	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.001	0.999	0.000
O65.0 Obstructed labour due to deformed pelvis	0.001	0.999	0.000
O66.8 Other specified obstructed labour	0.001	0.999	0.000
Q11.1 Other anophthalmos	0.001	0.999	0.000
Q90.9 Down's syndrome, unspecified	0.001	0.999	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.999	0.001
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.001	0.999	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.001	0.999	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.001	0.999	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.001	0.999	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.001	0.999	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.001	0.999	0.000
S86 Injury of muscle and tendon at lower leg level	0.000	0.999	0.001
S80-S89 Injuries to the knee and lower leg	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.999	0.001
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.999	0.001
O62.0 Primary inadequate contractions	0.001	0.999	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.001	0.999	0.000
Q15.0 Congenital glaucoma	0.001	0.999	0.000
R01.0 Benign and innocent cardiac murmurs	0.001	0.999	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.999	0.001
Q99 Other chromosome abnormalities, not elsewhere classified	0.001	0.999	0.000
O75.8 Other specified complications of labour and delivery	0.001	0.999	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.001	0.999	0.000
C45.9 Mesothelioma, unspecified	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.999	0.001
Y42.5 Other oestrogens and progestogens	0.000	0.999	0.001
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.001	0.999	0.000
Q35-Q37 Cleft lip and cleft palate	0.001	0.999	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.999	0.000
N91.2 Amenorrhoea, unspecified	0.000	0.999	0.001
Q90.2 Trisomy 21, translocation	0.001	0.999	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.001	0.999	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.001	0.999	0.000
O66 Other obstructed labour	0.001	0.999	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.001	0.999	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999	0.000
I51.8 Other ill-defined heart diseases	0.001	0.999	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.999	0.001
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.999	0.001
K74.1 Hepatic sclerosis	0.000	0.999	0.001
O66.4 Failed trial of labour, unspecified	0.001	0.999	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.001	0.999	0.000
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.999	0.001
S02.4 Fracture of malar and maxillary bones	0.001	0.999	0.000
S83.2 Tear of meniscus, current	0.000	0.999	0.001
Q15 Other congenital malformations of eye	0.001	0.999	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.001	0.999	0.000
E80.6 Other disorders of bilirubin metabolism	0.001	0.999	0.000
H92.1 Otorrhoea	0.000	0.999	0.001
K08.8 Other specified disorders of teeth and supporting structures	0.001	0.999	0.000
O62.8 Other abnormalities of forces of labour	0.001	0.999	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.999	0.001
X45.0 Home	0.000	0.999	0.001
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.001	0.999	0.000
O74 Complications of anaesthesia during labour and delivery	0.001	0.999	0.000
O60-O75 Complications of labour and delivery	0.001	0.999	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.000	0.999	0.001
A40.8 Other streptococcal septicaemia	0.001	0.999	0.000
C69.3 Choroid	0.000	0.999	0.001
G71.1 Myotonic disorders	0.000	0.999	0.001
J33.8 Other polyp of sinus	0.001	0.999	0.000
K50.8 Other Crohn's disease	0.000	0.999	0.001
O30.0 Twin pregnancy	0.001	0.999	0.000
O75.3 Other infection during labour	0.001	0.999	0.000
Q91.7 Patau's syndrome, unspecified	0.001	0.999	0.000
Q91.6 Trisomy 13, translocation	0.001	0.999	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.001	0.999	0.000
Q91.3 Edwards' syndrome, unspecified	0.001	0.999	0.000
Q91.2 Trisomy 18, translocation	0.001	0.999	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.001	0.999	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.001	0.999	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.001	0.999	0.000
Q92.7 Triploidy and polyploidy	0.001	0.999	0.000
Q92.6 Extra marker chromosomes	0.001	0.999	0.000
Q92.5 Duplications with other complex rearrangements	0.001	0.999	0.000
Q92.4 Duplications seen only at prometaphase	0.001	0.999	0.000
Q92.3 Minor partial trisomy	0.001	0.999	0.000
Q92.2 Major partial trisomy	0.001	0.999	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.001	0.999	0.000
Q93.9 Deletion from autosomes, unspecified	0.001	0.999	0.000
Q93.8 Other deletions from the autosomes	0.001	0.999	0.000
Q93.7 Deletions with other complex rearrangements	0.001	0.999	0.000
Q93.6 Deletions seen only at prometaphase	0.001	0.999	0.000
Q93.5 Other deletions of part of a chromosome	0.001	0.999	0.000
Q93.4 Deletion of short arm of chromosome 5	0.001	0.999	0.000
Q93.3 Deletion of short arm of chromosome 4	0.001	0.999	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.001	0.999	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.001	0.999	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.001	0.999	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.001	0.999	0.000
Q95.8 Other balanced rearrangements and structural markers	0.001	0.999	0.000
Q95.5 Individuals with autosomal fragile site	0.001	0.999	0.000
Q95.4 Individuals with marker heterochromatin	0.001	0.999	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.001	0.999	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.001	0.999	0.000
Q95.1 Chromosome inversion in normal individual	0.001	0.999	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.001	0.999	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.001	0.999	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.001	0.999	0.000
Q97.3 Female with 46,XY karyotype	0.001	0.999	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.001	0.999	0.000
Q97.1 Female with more than three X chromosomes	0.001	0.999	0.000
Q97.0 Karyotype 47,XXX	0.001	0.999	0.000
R45.1 Restlessness and agitation	0.000	0.999	0.001
S86.0 Injury of Achilles tendon	0.000	0.999	0.001
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.999	0.001
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.999	0.001
Q35 Cleft palate	0.001	0.999	0.000
S88 Traumatic amputation of lower leg	0.000	0.999	0.001
S87 Crushing injury of lower leg	0.000	0.999	0.001
S85 Injury of blood vessels at lower leg level	0.000	0.999	0.001
S84 Injury of nerves at lower leg level	0.000	0.999	0.001
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.000	0.999	0.001
M25.86 Other specified joint disorders (Lower leg)	0.000	0.999	0.001
S82.70 Multiple fractures of lower leg (closed)	0.001	0.999	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.001	0.999	0.000
Q99.9 Chromosomal abnormality, unspecified	0.001	0.999	0.000
Q99.2 Fragile X chromosome	0.001	0.999	0.000
Q99.1 46,XX true hermaphrodite	0.001	0.999	0.000
Q99.0 Chimera 46,XX/46,XY	0.001	0.999	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.999	0.001
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.999	0.001
O62 Abnormalities of forces of labour	0.001	0.999	0.000
B27.9 Infectious mononucleosis, unspecified	0.001	0.999	0.000
O66.2 Obstructed labour due to unusually large foetus	0.001	0.999	0.000
Q35.9 Cleft palate, unspecified	0.001	0.999	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.001	0.999	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.001	0.999	0.000
Q98.7 Male with sex chromosome mosaicism	0.001	0.999	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.001	0.999	0.000
Q98.5 Karyotype 47,XYY	0.001	0.999	0.000
Q98.3 Other male with 46,XX karyotype	0.001	0.999	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.001	0.999	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.001	0.999	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations