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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10815381
log Bayes Factor = 0.338114
Chromosome 9   position 6,226,289  (GRCh37) Explore rs10815381 on Ensembl!
Variant rs10815381 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06 Other rheumatoid arthritis
0.572 0.428 0.000
M05-M14 Inflammatory polyarthropathies
0.567 0.433 0.000
M06.0 Seronegative rheumatoid arthritis
0.562 0.438 0.000
M06.9 Rheumatoid arthritis, unspecified
0.553 0.447 0.000
M10 Gout
0.541 0.459 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.532 0.468 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.530 0.470 0.000
M11 Other crystal arthropathies
0.528 0.472 0.000
M10.9 Gout, unspecified
0.504 0.496 0.000
M11.2 Other chondrocalcinosis
0.495 0.505 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.481 0.519 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.476 0.524 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.472 0.528 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.472 0.528 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.467 0.533 0.000
M86-M90 Other osteopathies
0.460 0.540 0.000
M60-M63 Disorders of muscles
0.460 0.540 0.000
M10.96 Gout, unspecified (Lower leg)
0.457 0.543 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.457 0.543 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.455 0.545 0.000
M87 Osteonecrosis
0.454 0.546 0.000
M87.2 Osteonecrosis due to previous trauma
0.451 0.549 0.000
M05 Seropositive rheumatoid arthritis
0.450 0.550 0.000
M10.0 Idiopathic gout
0.450 0.550 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.449 0.551 0.000
M87.20 Osteonecrosis due to previous trauma (Multiple sites)
0.447 0.553 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.446 0.554 0.000
M62 Other disorders of muscle
0.442 0.558 0.000
M14 Arthropathies in other diseases classified elsewhere
0.442 0.558 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.441 0.559 0.000
M06.4 Inflammatory polyarthropathy
0.440 0.560 0.000
M95.0 Acquired deformity of nose
0.438 0.562 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.435 0.565 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.432 0.568 0.000
M80-M85 Disorders of bone density and structure
0.432 0.568 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.430 0.570 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.418 0.582 0.000
M40-M43 Deforming dorsopathies
0.412 0.588 0.000
M11.8 Other specified crystal arthropathies
0.411 0.589 0.000
M10.3 Gout due to impairment of renal function
0.411 0.589 0.000
M06.8 Other specified rheumatoid arthritis
0.410 0.590 0.000
M06.2 Rheumatoid bursitis
0.410 0.590 0.000
M06.1 Adult-onset Still's disease
0.410 0.590 0.000
M62.8 Other specified disorders of muscle
0.409 0.591 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.407 0.593 0.000
M08 Juvenile arthritis
0.407 0.593 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.403 0.597 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.403 0.597 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.403 0.597 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.403 0.597 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.403 0.597 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.403 0.597 0.000
M10.90 Gout, unspecified (Multiple sites)
0.399 0.601 0.000
M10.94 Gout, unspecified (Hand)
0.394 0.606 0.000
M10.4 Other secondary gout
0.388 0.612 0.000
M10.2 Drug-induced gout
0.388 0.612 0.000
M10.1 Lead-induced gout
0.388 0.612 0.000
M10.09 Idiopathic gout (Site unspecified)
0.388 0.612 0.000
M82 Osteoporosis in diseases classified elsewhere
0.383 0.617 0.000
M12 Other specific arthropathies
0.379 0.621 0.000
M11.1 Familial chondrocalcinosis
0.379 0.621 0.000
M11.0 Hydroxyapatite deposition disease
0.379 0.621 0.000
M06.3 Rheumatoid nodule
0.376 0.624 0.000
M60 Myositis
0.375 0.625 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.373 0.627 0.000
M65-M68 Disorders of synovium and tendon
0.372 0.628 0.000
M84 Disorders of continuity of bone
0.369 0.631 0.000
M11.9 Crystal arthropathy, unspecified
0.367 0.632 0.000
M81 Osteoporosis without pathological fracture
0.365 0.635 0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified
0.365 0.635 0.000
M62.1 Other rupture of muscle (nontraumatic)
0.363 0.637 0.000
M62.85 Other specified disorders of muscle (Pelvic region and thigh)
0.362 0.638 0.000
M10.98 Gout, unspecified (Other)
0.362 0.638 0.000
M10.95 Gout, unspecified (Pelvic region and thigh)
0.362 0.638 0.000
M10.91 Gout, unspecified (Shoulder region)
0.362 0.638 0.000
M62.86 Other specified disorders of muscle (Lower leg)
0.361 0.639 0.000
M11.29 Other chondrocalcinosis (Site unspecified)
0.355 0.645 0.000
M11.28 Other chondrocalcinosis (Other)
0.355 0.645 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.355 0.645 0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)
0.355 0.645 0.000
M11.24 Other chondrocalcinosis (Hand)
0.355 0.645 0.000
M11.23 Other chondrocalcinosis (Forearm)
0.355 0.645 0.000
M11.22 Other chondrocalcinosis (Upper arm)
0.355 0.645 0.000
M11.21 Other chondrocalcinosis (Shoulder region)
0.355 0.645 0.000
M11.20 Other chondrocalcinosis (Multiple sites)
0.355 0.645 0.000
M00-M03 Infectious arthropathies
0.354 0.645 0.000
M07 Psoriatic and enteropathic arthropathies
0.352 0.648 0.000
M87.3 Other secondary osteonecrosis
0.349 0.650 0.000
M87.27 Osteonecrosis due to previous trauma (Ankle and foot)
0.348 0.652 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.348 0.652 0.000
M41 Scoliosis
0.348 0.652 0.000
M82.1 Osteoporosis in endocrine disorders
0.347 0.652 0.000
M87.25 Osteonecrosis due to previous trauma (Pelvic region and thigh)
0.347 0.653 0.000
M05.2 Rheumatoid vasculitis
0.346 0.654 0.000
M62.88 Other specified disorders of muscle (Other)
0.346 0.654 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.341 0.659 0.000
M90 Osteopathies in diseases classified elsewhere
0.341 0.659 0.000
M88 Paget's disease of bone [osteitis deformans]
0.338 0.662 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.337 0.663 0.000
M86 Osteomyelitis
0.332 0.667 0.000
M87.8 Other osteonecrosis
0.332 0.668 0.000
M10.93 Gout, unspecified (Forearm)
0.330 0.670 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.330 0.670 0.000
M61 Calcification and ossification of muscle
0.330 0.670 0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)
0.329 0.671 0.000
M40 Kyphosis and lordosis
0.329 0.671 0.000
M14.2 Diabetic arthropathy
0.328 0.672 0.000
M95.4 Acquired deformity of chest and rib
0.328 0.672 0.000
M11.86 Other specified crystal arthropathies (Lower leg)
0.328 0.672 0.000
M62.83 Other specified disorders of muscle (Forearm)
0.326 0.674 0.000
M87.1 Osteonecrosis due to drugs
0.326 0.674 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.326 0.674 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.326 0.674 0.000
M13 Other arthritis
0.326 0.674 0.000
M87.29 Osteonecrosis due to previous trauma (Site unspecified)
0.323 0.676 0.000
M87.28 Osteonecrosis due to previous trauma (Other)
0.323 0.676 0.000
M87.26 Osteonecrosis due to previous trauma (Lower leg)
0.323 0.676 0.000
M87.24 Osteonecrosis due to previous trauma (Hand)
0.323 0.676 0.000
M87.23 Osteonecrosis due to previous trauma (Forearm)
0.323 0.676 0.000
M87.22 Osteonecrosis due to previous trauma (Upper arm)
0.323 0.676 0.000
M87.21 Osteonecrosis due to previous trauma (Shoulder region)
0.323 0.676 0.000
M05.8 Other seropositive rheumatoid arthritis
0.323 0.677 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.323 0.677 0.000
M05.1 Rheumatoid lung disease
0.323 0.677 0.000
M05.0 Felty's syndrome
0.323 0.677 0.000
M99 Biomechanical lesions, not elsewhere classified
0.323 0.677 0.000
M10.08 Idiopathic gout (Other)
0.322 0.677 0.000
M10.06 Idiopathic gout (Lower leg)
0.322 0.677 0.000
M10.05 Idiopathic gout (Pelvic region and thigh)
0.322 0.677 0.000
M10.04 Idiopathic gout (Hand)
0.322 0.677 0.000
M10.03 Idiopathic gout (Forearm)
0.322 0.677 0.000
M10.02 Idiopathic gout (Upper arm)
0.322 0.677 0.000
M10.01 Idiopathic gout (Shoulder region)
0.322 0.677 0.000
M10.00 Idiopathic gout (Multiple sites)
0.322 0.677 0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)
0.320 0.680 0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)
0.318 0.681 0.000
M10.39 Gout due to impairment of renal function (Site unspecified)
0.318 0.682 0.000
M62.80 Other specified disorders of muscle (Multiple sites)
0.318 0.682 0.000
M62.9 Disorder of muscle, unspecified
0.317 0.683 0.000
M62.4 Contracture of muscle
0.317 0.683 0.000
M62.3 Immobility syndrome (paraplegic)
0.317 0.683 0.000
M62.2 Ischaemic infarction of muscle
0.317 0.683 0.000
M62.0 Diastasis of muscle
0.317 0.683 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.317 0.683 0.000
M14.4 Arthropathy in amyloidosis
0.317 0.683 0.000
M14.3 Lipoid dermatoarthritis
0.317 0.683 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.317 0.683 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.317 0.683 0.000
M62.6 Muscle strain
0.316 0.684 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.316 0.684 0.000
M95.8 Other specified acquired deformities of musculoskeletal system
0.316 0.684 0.000
M95.5 Acquired deformity of pelvis
0.316 0.684 0.000
M95.1 Cauliflower ear
0.316 0.684 0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)
0.316 0.684 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.316 0.684 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.316 0.684 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.316 0.684 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.316 0.684 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.316 0.684 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.316 0.684 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.316 0.684 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.316 0.684 0.000
M95.3 Acquired deformity of neck
0.315 0.684 0.000
M66 Spontaneous rupture of synovium and tendon
0.315 0.685 0.000
M10.07 Idiopathic gout (Ankle and foot)
0.314 0.686 0.000
M41.9 Scoliosis, unspecified
0.313 0.687 0.000
M67 Other disorders of synovium and tendon
0.312 0.688 0.000
M81.9 Osteoporosis, unspecified
0.311 0.689 0.000
M62.84 Other specified disorders of muscle (Hand)
0.310 0.690 0.000
M83 Adult osteomalacia
0.310 0.690 0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)
0.307 0.693 0.000
M60.9 Myositis, unspecified
0.299 0.701 0.000
M87.9 Osteonecrosis, unspecified
0.297 0.702 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.298 0.702 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.297 0.703 0.000
M43 Other deforming dorsopathies
0.296 0.704 0.000
M42 Spinal osteochondrosis
0.296 0.704 0.000
M11.89 Other specified crystal arthropathies (Site unspecified)
0.295 0.705 0.000
M11.88 Other specified crystal arthropathies (Other)
0.295 0.705 0.000
M11.87 Other specified crystal arthropathies (Ankle and foot)
0.295 0.705 0.000
M11.85 Other specified crystal arthropathies (Pelvic region and thigh)
0.295 0.705 0.000
M11.84 Other specified crystal arthropathies (Hand)
0.295 0.705 0.000
M11.83 Other specified crystal arthropathies (Forearm)
0.295 0.705 0.000
M11.82 Other specified crystal arthropathies (Upper arm)
0.295 0.705 0.000
M11.81 Other specified crystal arthropathies (Shoulder region)
0.295 0.705 0.000
M11.80 Other specified crystal arthropathies (Multiple sites)
0.295 0.705 0.000
M10.38 Gout due to impairment of renal function (Other)
0.295 0.705 0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)
0.295 0.705 0.000
M10.36 Gout due to impairment of renal function (Lower leg)
0.295 0.705 0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)
0.295 0.705 0.000
M10.34 Gout due to impairment of renal function (Hand)
0.295 0.705 0.000
M10.33 Gout due to impairment of renal function (Forearm)
0.295 0.705 0.000
M10.32 Gout due to impairment of renal function (Upper arm)
0.295 0.705 0.000
M10.31 Gout due to impairment of renal function (Shoulder region)
0.295 0.705 0.000
M10.30 Gout due to impairment of renal function (Multiple sites)
0.295 0.705 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.294 0.705 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.294 0.706 0.000
M06.18 Adult-onset Still's disease (Other)
0.294 0.706 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.294 0.706 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.294 0.706 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.294 0.706 0.000
M06.14 Adult-onset Still's disease (Hand)
0.294 0.706 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.294 0.706 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.294 0.706 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.294 0.706 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.294 0.706 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.294 0.706 0.000
M06.28 Rheumatoid bursitis (Other)
0.294 0.706 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.294 0.706 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.294 0.706 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.294 0.706 0.000
M06.24 Rheumatoid bursitis (Hand)
0.294 0.706 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.294 0.706 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.294 0.706 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.294 0.706 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.294 0.706 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.294 0.706 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.294 0.706 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.294 0.706 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.294 0.706 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.294 0.706 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.294 0.706 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.294 0.706 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.294 0.706 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.294 0.706 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.294 0.706 0.000
M67.1 Other contracture of tendon (sheath)
0.294 0.706 0.000
M62.87 Other specified disorders of muscle (Ankle and foot)
0.293 0.707 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.292 0.708 0.000
M08.9 Juvenile arthritis, unspecified
0.292 0.708 0.000
M08.8 Other juvenile arthritis
0.292 0.708 0.000
M08.4 Pauciarticular juvenile arthritis
0.292 0.708 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.292 0.708 0.000
M08.2 Juvenile arthritis with systemic onset
0.292 0.708 0.000
M08.1 Juvenile ankylosing spondylitis
0.292 0.708 0.000
M08.0 Juvenile rheumatoid arthritis
0.292 0.708 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.292 0.708 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.292 0.708 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.292 0.708 0.000
M09.0 Juvenile arthritis in psoriasis
0.292 0.708 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.290 0.710 0.000
M60.0 Infective myositis
0.290 0.710 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.289 0.711 0.000
M10.99 Gout, unspecified (Site unspecified)
0.289 0.711 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.284 0.716 0.000
M66.0 Rupture of popliteal cyst
0.282 0.718 0.000
M81.4 Drug-induced osteoporosis
0.281 0.718 0.000
M10.19 Lead-induced gout (Site unspecified)
0.278 0.721 0.000
M10.18 Lead-induced gout (Other)
0.278 0.721 0.000
M10.17 Lead-induced gout (Ankle and foot)
0.278 0.721 0.000
M10.16 Lead-induced gout (Lower leg)
0.278 0.721 0.000
M10.15 Lead-induced gout (Pelvic region and thigh)
0.278 0.721 0.000
M10.14 Lead-induced gout (Hand)
0.278 0.721 0.000
M10.13 Lead-induced gout (Forearm)
0.278 0.721 0.000
M10.12 Lead-induced gout (Upper arm)
0.278 0.721 0.000
M10.11 Lead-induced gout (Shoulder region)
0.278 0.721 0.000
M10.10 Lead-induced gout (Multiple sites)
0.278 0.721 0.000
M10.29 Drug-induced gout (Site unspecified)
0.278 0.721 0.000
M10.28 Drug-induced gout (Other)
0.278 0.721 0.000
M10.27 Drug-induced gout (Ankle and foot)
0.278 0.721 0.000
M10.26 Drug-induced gout (Lower leg)
0.278 0.721 0.000
M10.25 Drug-induced gout (Pelvic region and thigh)
0.278 0.721 0.000
M10.24 Drug-induced gout (Hand)
0.278 0.721 0.000
M10.23 Drug-induced gout (Forearm)
0.278 0.721 0.000
M10.22 Drug-induced gout (Upper arm)
0.278 0.721 0.000
M10.21 Drug-induced gout (Shoulder region)
0.278 0.721 0.000
M10.20 Drug-induced gout (Multiple sites)
0.278 0.721 0.000
M10.49 Other secondary gout (Site unspecified)
0.278 0.721 0.000
M10.48 Other secondary gout (Other)
0.278 0.721 0.000
M10.47 Other secondary gout (Ankle and foot)
0.278 0.721 0.000
M10.46 Other secondary gout (Lower leg)
0.278 0.721 0.000
M10.45 Other secondary gout (Pelvic region and thigh)
0.278 0.721 0.000
M10.44 Other secondary gout (Hand)
0.278 0.721 0.000
M10.43 Other secondary gout (Forearm)
0.278 0.721 0.000
M10.42 Other secondary gout (Upper arm)
0.278 0.721 0.000
M10.41 Other secondary gout (Shoulder region)
0.278 0.721 0.000
M10.40 Other secondary gout (Multiple sites)
0.278 0.721 0.000
M10.92 Gout, unspecified (Upper arm)
0.276 0.724 0.000
M82.8 Osteoporosis in other diseases classified elsewhere
0.274 0.725 0.000
M82.0 Osteoporosis in multiple myelomatosis
0.274 0.725 0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm
0.274 0.725 0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)
0.274 0.726 0.000
M85 Other disorders of bone density and structure
0.273 0.727 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.272 0.728 0.000
M12.5 Traumatic arthropathy
0.272 0.728 0.000
M12.4 Intermittent hydrarthrosis
0.272 0.728 0.000
M12.1 Kaschin-Beck disease
0.272 0.728 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.272 0.728 0.000
M11.09 Hydroxyapatite deposition disease (Site unspecified)
0.272 0.728 0.000
M11.08 Hydroxyapatite deposition disease (Other)
0.272 0.728 0.000
M11.07 Hydroxyapatite deposition disease (Ankle and foot)
0.272 0.728 0.000
M11.06 Hydroxyapatite deposition disease (Lower leg)
0.272 0.728 0.000
M11.05 Hydroxyapatite deposition disease (Pelvic region and thigh)
0.272 0.728 0.000
M11.04 Hydroxyapatite deposition disease (Hand)
0.272 0.728 0.000
M11.03 Hydroxyapatite deposition disease (Forearm)
0.272 0.728 0.000
M11.02 Hydroxyapatite deposition disease (Upper arm)
0.272 0.728 0.000
M11.01 Hydroxyapatite deposition disease (Shoulder region)
0.272 0.728 0.000
M11.00 Hydroxyapatite deposition disease (Multiple sites)
0.272 0.728 0.000
M11.19 Familial chondrocalcinosis (Site unspecified)
0.272 0.728 0.000
M11.18 Familial chondrocalcinosis (Other)
0.272 0.728 0.000
M11.17 Familial chondrocalcinosis (Ankle and foot)
0.272 0.728 0.000
M11.16 Familial chondrocalcinosis (Lower leg)
0.272 0.728 0.000
M11.15 Familial chondrocalcinosis (Pelvic region and thigh)
0.272 0.728 0.000
M11.14 Familial chondrocalcinosis (Hand)
0.272 0.728 0.000
M11.13 Familial chondrocalcinosis (Forearm)
0.272 0.728 0.000
M11.12 Familial chondrocalcinosis (Upper arm)
0.272 0.728 0.000
M11.11 Familial chondrocalcinosis (Shoulder region)
0.272 0.728 0.000
M11.10 Familial chondrocalcinosis (Multiple sites)
0.272 0.728 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.272 0.728 0.000
M84.3 Stress fracture, not elsewhere classified
0.272 0.728 0.000
M12.2 Villonodular synovitis (pigmented)
0.271 0.728 0.000
M13.8 Other specified arthritis
0.271 0.729 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.269 0.730 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.269 0.730 0.000
M06.38 Rheumatoid nodule (Other)
0.269 0.730 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.269 0.730 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.269 0.730 0.000
M06.33 Rheumatoid nodule (Forearm)
0.269 0.730 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.269 0.730 0.000
M40.5 Lordosis, unspecified
0.269 0.731 0.000
M60.8 Other myositis
0.269 0.731 0.000
M60.2 Foreign body granuloma of soft tissue, not elsewhere classified
0.269 0.731 0.000
M60.1 Interstitial myositis
0.269 0.731 0.000
M84.2 Delayed union of fracture
0.268 0.732 0.000
M62.82 Other specified disorders of muscle (Upper arm)
0.267 0.733 0.000
M00 Pyogenic arthritis
0.267 0.733 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.267 0.733 0.000
M40.1 Other secondary kyphosis
0.266 0.733 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.265 0.735 0.000
M81.2 Osteoporosis of disuse
0.265 0.735 0.000
M84.9 Disorder of continuity of bone, unspecified
0.264 0.735 0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)
0.264 0.736 0.000
M11.98 Crystal arthropathy, unspecified (Other)
0.264 0.736 0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)
0.264 0.736 0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)
0.264 0.736 0.000
M11.94 Crystal arthropathy, unspecified (Hand)
0.264 0.736 0.000
M11.93 Crystal arthropathy, unspecified (Forearm)
0.264 0.736 0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)
0.264 0.736 0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)
0.264 0.736 0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)
0.264 0.736 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.264 0.736 0.000
M90.6 Osteitis deformans in neoplastic disease
0.262 0.737 0.000
M81.8 Other osteoporosis
0.262 0.738 0.000
M81.6 Localised osteoporosis [Lequesne]
0.262 0.738 0.000
M81.5 Idiopathic osteoporosis
0.262 0.738 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.262 0.738 0.000
M81.1 Postoophorectomy osteoporosis
0.262 0.738 0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)
0.262 0.738 0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)
0.262 0.738 0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)
0.262 0.738 0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)
0.262 0.738 0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)
0.262 0.738 0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)
0.262 0.738 0.000
M14.6 Neuropathic arthropathy
0.261 0.739 0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)
0.261 0.739 0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)
0.261 0.739 0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)
0.261 0.739 0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)
0.261 0.739 0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)
0.261 0.739 0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)
0.261 0.739 0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)
0.261 0.739 0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)
0.261 0.739 0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)
0.261 0.739 0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)
0.261 0.739 0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)
0.260 0.740 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.260 0.740 0.000
M84.4 Pathological fracture, not elsewhere classified
0.260 0.740 0.000
M66.06 Rupture of popliteal cyst-Lower leg
0.258 0.742 0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)
0.258 0.742 0.000
M87.86 Other osteonecrosis (Lower leg)
0.256 0.743 0.000
M95.2 Other acquired deformity of head
0.254 0.745 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.254 0.746 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.254 0.746 0.000
M02 Reactive arthropathies
0.254 0.746 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.254 0.746 0.000
M84.8 Other disorders of continuity of bone
0.253 0.747 0.000
M07.6 Other enteropathic arthropathies
0.253 0.747 0.000
M07.5 Arthropathy in ulcerative colitis
0.253 0.747 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.253 0.747 0.000
M07.2 Psoriatic spondylitis
0.253 0.747 0.000
M07.1 Arthritis mutilans
0.253 0.747 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.253 0.747 0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)
0.252 0.748 0.000
M81.0 Postmenopausal osteoporosis
0.251 0.749 0.000
M87.39 Other secondary osteonecrosis (Site unspecified)
0.251 0.749 0.000
M87.38 Other secondary osteonecrosis (Other)
0.251 0.749 0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)
0.251 0.749 0.000
M87.36 Other secondary osteonecrosis (Lower leg)
0.251 0.749 0.000
M87.34 Other secondary osteonecrosis (Hand)
0.251 0.749 0.000
M87.33 Other secondary osteonecrosis (Forearm)
0.251 0.749 0.000
M87.32 Other secondary osteonecrosis (Upper arm)
0.251 0.749 0.000
M87.31 Other secondary osteonecrosis (Shoulder region)
0.251 0.749 0.000
M87.30 Other secondary osteonecrosis (Multiple sites)
0.251 0.749 0.000
M88.9 Paget's disease of bone, unspecified
0.250 0.750 0.000
M90.7 Fracture of bone in neoplastic disease
0.250 0.750 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.249 0.750 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.249 0.750 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.249 0.750 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.249 0.750 0.000
M41.5 Other secondary scoliosis
0.249 0.751 0.000
M41.4 Neuromuscular scoliosis
0.249 0.751 0.000
M41.3 Thoracogenic scoliosis
0.249 0.751 0.000
M41.2 Other idiopathic scoliosis
0.249 0.751 0.000
M41.1 Juvenile idiopathic scoliosis
0.249 0.751 0.000
M41.0 Infantile idiopathic scoliosis
0.249 0.751 0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)
0.249 0.751 0.000
M82.18 Osteoporosis in endocrine disorders (Other)
0.249 0.751 0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)
0.249 0.751 0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)
0.249 0.751 0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)
0.249 0.751 0.000
M82.14 Osteoporosis in endocrine disorders (Hand)
0.249 0.751 0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)
0.249 0.751 0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)
0.249 0.751 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.249 0.751 0.000
M43.2 Other fusion of spine
0.249 0.751 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.248 0.751 0.000
M05.28 Rheumatoid vasculitis (Other)
0.248 0.751 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.248 0.751 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.248 0.751 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.248 0.751 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.248 0.751 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.248 0.751 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.248 0.751 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.248 0.751 0.000
M86.6 Other chronic osteomyelitis
0.248 0.752 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.248 0.752 0.000
M66.5 Spontaneous rupture of unspecified tendon
0.246 0.754 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.245 0.755 0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)
0.245 0.755 0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)
0.245 0.755 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.245 0.755 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.245 0.755 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.245 0.755 0.000
M90.3 Osteonecrosis in caisson disease
0.245 0.755 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.245 0.755 0.000
M90.0 Tuberculosis of bone
0.245 0.755 0.000
M12.3 Palindromic rheumatism
0.244 0.755 0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)
0.244 0.755 0.000
M88.0 Paget's disease of skull
0.242 0.757 0.000
M88.8 Paget's disease of other bones
0.242 0.758 0.000
M13.0 Polyarthritis, unspecified
0.242 0.758 0.000
M60.95 Myositis, unspecified (Pelvic region and thigh)
0.242 0.758 0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina
0.242 0.758 0.000
M66.3 Spontaneous rupture of flexor tendons
0.239 0.761 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.238 0.761 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.238 0.761 0.000
M86.3 Chronic multifocal osteomyelitis
0.238 0.761 0.000
M86.2 Subacute osteomyelitis
0.238 0.761 0.000
M86.1 Other acute osteomyelitis
0.238 0.761 0.000
M86.0 Acute haematogenous osteomyelitis
0.238 0.761 0.000
M86.8 Other osteomyelitis
0.238 0.762 0.000
M87.89 Other osteonecrosis (Site unspecified)
0.238 0.762 0.000
M87.88 Other osteonecrosis (Other)
0.238 0.762 0.000
M87.87 Other osteonecrosis (Ankle and foot)
0.238 0.762 0.000
M87.84 Other osteonecrosis (Hand)
0.238 0.762 0.000
M87.83 Other osteonecrosis (Forearm)
0.238 0.762 0.000
M87.82 Other osteonecrosis (Upper arm)
0.238 0.762 0.000
M87.81 Other osteonecrosis (Shoulder region)
0.238 0.762 0.000
M87.80 Other osteonecrosis (Multiple sites)
0.238 0.762 0.000
M60.05 Infective myositis (Pelvic region and thigh)
0.237 0.762 0.000
M61.9 Calcification and ossification of muscle, unspecified
0.237 0.763 0.000
M61.5 Other ossification of muscle
0.237 0.763 0.000
M61.4 Other calcification of muscle
0.237 0.763 0.000
M61.3 Calcification and ossification of muscles associated with burns
0.237 0.763 0.000
M61.2 Paralytic calcification and ossification of muscle
0.237 0.763 0.000
M61.1 Myositis ossificans progressiva
0.237 0.763 0.000
M61.0 Myositis ossificans traumatica
0.237 0.763 0.000
M63.8 Other disorders of muscle in diseases classified elsewhere
0.237 0.763 0.000
M63.3 Myositis in sarcoidosis
0.237 0.763 0.000
M63.2 Myositis in other infectious diseases classified elsewhere
0.237 0.763 0.000
M63.1 Myositis in protozoal and parasitic infections classified elsewhere
0.237 0.763 0.000
M63.0 Myositis in bacterial diseases classified elsewhere
0.237 0.763 0.000
M40.4 Other lordosis
0.236 0.764 0.000
M40.3 Flatback syndrome
0.236 0.764 0.000
M40.0 Postural kyphosis
0.236 0.764 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.235 0.764 0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)
0.234 0.766 0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)
0.234 0.766 0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)
0.234 0.766 0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)
0.234 0.766 0.000
M87.05 Idiopathic aseptic necrosis of bone (Pelvic region and thigh)
0.234 0.766 0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)
0.234 0.766 0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)
0.234 0.766 0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)
0.234 0.766 0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)
0.234 0.766 0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)
0.234 0.766 0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)
0.234 0.766 0.000
M87.18 Osteonecrosis due to drugs (Other)
0.234 0.766 0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)
0.234 0.766 0.000
M87.16 Osteonecrosis due to drugs (Lower leg)
0.234 0.766 0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)
0.234 0.766 0.000
M87.14 Osteonecrosis due to drugs (Hand)
0.234 0.766 0.000
M87.13 Osteonecrosis due to drugs (Forearm)
0.234 0.766 0.000
M87.12 Osteonecrosis due to drugs (Upper arm)
0.234 0.766 0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)
0.234 0.766 0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)
0.234 0.766 0.000
M13.1 Monoarthritis, not elsewhere classified
0.233 0.767 0.000
M05.09 Felty's syndrome (Site unspecified)
0.232 0.768 0.000
M05.08 Felty's syndrome (Other)
0.232 0.768 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.232 0.768 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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