TreeWAS – Variant ID: rs10821136

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.9 Crohn's disease, unspecified	0.000	0.495	0.505
K50 Crohn's disease [regional enteritis]	0.000	0.590	0.410
K50.1 Crohn's disease of large intestine	0.000	0.601	0.399
K50.8 Other Crohn's disease	0.000	0.693	0.307
K81.0 Acute cholecystitis	0.000	0.706	0.294
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.711	0.289
K80 Cholelithiasis	0.000	0.712	0.288
K80.0 Calculus of gallbladder with acute cholecystitis	0.000	0.714	0.286
K81 Cholecystitis	0.000	0.717	0.283
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.000	0.727	0.273
K80.8 Other cholelithiasis	0.000	0.733	0.267
K81.1 Chronic cholecystitis	0.000	0.745	0.255
K86 Other diseases of pancreas	0.000	0.756	0.244
K86.1 Other chronic pancreatitis	0.000	0.759	0.241
K86.2 Cyst of pancreas	0.000	0.777	0.223
K81.8 Other cholecystitis	0.000	0.788	0.212
K80.3 Calculus of bile duct with cholangitis	0.000	0.793	0.207
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.000	0.804	0.196
K85 Acute pancreatitis	0.000	0.836	0.164
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.000	0.852	0.148
K50.0 Crohn's disease of small intestine	0.000	0.853	0.147
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.854	0.146
K87.1 Disorders of pancreas in diseases classified elsewhere	0.000	0.859	0.141
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.000	0.859	0.141
K85.9 Acute pancreatitis, unspecified	0.000	0.866	0.134
K80.4 Calculus of bile duct with cholecystitis	0.000	0.866	0.134
K82 Other diseases of gallbladder	0.000	0.869	0.131
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.000	0.874	0.126
K86.8 Other specified diseases of pancreas	0.000	0.876	0.124
K82.4 Cholesterolosis of gallbladder	0.000	0.878	0.122
K85.8 Other acute pancreatitis	0.000	0.880	0.120
K85.3 Drug-induced acute pancreatitis	0.000	0.882	0.118
K85.0 Idiopathic acute pancreatitis	0.000	0.883	0.116
K82.9 Disease of gallbladder, unspecified	0.000	0.892	0.108
K86.3 Pseudocyst of pancreas	0.000	0.898	0.102
K85.2 Alcohol-induced acute pancreatitis	0.000	0.905	0.095
K82.0 Obstruction of gallbladder	0.000	0.906	0.094
K86.9 Disease of pancreas, unspecified	0.000	0.915	0.084
K82.3 Fistula of gallbladder	0.000	0.917	0.083
K85.1 Biliary acute pancreatitis	0.000	0.921	0.079
K50-K52 Noninfective enteritis and colitis	0.000	0.928	0.072
K81.9 Cholecystitis, unspecified	0.000	0.931	0.069
K82.1 Hydrops of gallbladder	0.000	0.935	0.065
K82.2 Perforation of gallbladder	0.001	0.959	0.040
Chapter XI Diseases of the digestive system	0.000	0.964	0.036
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.964	0.036
M35.3 Polymyalgia rheumatica	0.000	0.964	0.036
K80.2 Calculus of gallbladder without cholecystitis	0.000	0.968	0.032
K65-K67 Diseases of peritoneum	0.000	0.970	0.030
K65 Peritonitis	0.000	0.972	0.028
K65.0 Acute peritonitis	0.000	0.973	0.027
S83.2 Tear of meniscus, current	0.000	0.975	0.025
K65.9 Peritonitis, unspecified	0.000	0.976	0.024
K70-K77 Diseases of liver	0.000	0.977	0.023
K51 Ulcerative colitis	0.000	0.977	0.023
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.979	0.021
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.979	0.021
K76 Other diseases of liver	0.000	0.980	0.020
K76.9 Liver disease, unspecified	0.000	0.981	0.019
K65.8 Other peritonitis	0.000	0.981	0.019
F00.9 Dementia in Alzheimer's disease, unspecified	0.018	0.982	0.000
F00 Dementia in Alzheimer's disease	0.018	0.982	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.983	0.017
K51.4 Pseudopolyposis of colon	0.000	0.983	0.017
K73 Chronic hepatitis, not elsewhere classified	0.000	0.983	0.017
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.983	0.017
K76.6 Portal hypertension	0.000	0.983	0.017
K72 Hepatic failure, not elsewhere classified	0.000	0.983	0.017
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.983	0.017
K77 Liver disorders in diseases classified elsewhere	0.000	0.983	0.016
K74.3 Primary biliary cirrhosis	0.000	0.984	0.016
S61.9 Open wound of wrist and hand, part unspecified	0.016	0.984	0.000
K71 Toxic liver disease	0.000	0.984	0.016
F00-F09 Organic, including symptomatic, mental disorders	0.016	0.984	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.984	0.016
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.000	0.984	0.015
K67.3 Tuberculous peritonitis	0.000	0.984	0.015
K67.2 Syphilitic peritonitis	0.000	0.984	0.015
K67.1 Gonococcal peritonitis	0.000	0.984	0.015
K67.0 Chlamydial peritonitis	0.000	0.984	0.015
K51.5 Mucosal proctocolitis	0.000	0.984	0.016
F03 Unspecified dementia	0.015	0.985	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.015	0.985	0.000
K52 Other non-infective gastro-enteritis and colitis	0.000	0.985	0.015
K76.1 Chronic passive congestion of liver	0.000	0.985	0.015
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.015	0.985	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.015	0.985	0.000
K62.5 Haemorrhage of anus and rectum	0.000	0.985	0.015
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.986	0.014
K76.5 Hepatic veno-occlusive disease	0.000	0.986	0.014
K76.4 Peliosis hepatis	0.000	0.986	0.014
K76.3 Infarction of liver	0.000	0.986	0.014
K76.2 Central haemorrhagic necrosis of liver	0.000	0.986	0.014
K73.9 Chronic hepatitis, unspecified	0.000	0.986	0.014
F07.0 Organic personality disorder	0.014	0.986	0.000
F02 Dementia in other diseases classified elsewhere	0.014	0.986	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.986	0.014
K76.7 Hepatorenal syndrome	0.000	0.986	0.013
S83.7 Injury to multiple structures of knee	0.000	0.987	0.013
K72.1 Chronic hepatic failure	0.000	0.987	0.013
S83.3 Tear of articular cartilage of knee, current	0.000	0.987	0.013
F00.0 Dementia in Alzheimer's disease with early onset	0.013	0.987	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.987	0.013
K74.4 Secondary biliary cirrhosis	0.000	0.987	0.013
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.987	0.013
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.987	0.013
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.987	0.013
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.987	0.012
F09 Unspecified organic or symptomatic mental disorder	0.013	0.987	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.000	0.988	0.012
K72.0 Acute and subacute hepatic failure	0.000	0.988	0.012
S83.1 Dislocation of knee	0.000	0.988	0.012
S83.0 Dislocation of patella	0.000	0.988	0.012
F02.8 Dementia in other specified diseases classified elsewhere	0.012	0.988	0.000
K58 Irritable bowel syndrome	0.000	0.988	0.012
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.988	0.012
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.988	0.012
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.988	0.012
K74.0 Hepatic fibrosis	0.000	0.988	0.012
K71.9 Toxic liver disease, unspecified	0.000	0.988	0.012
K71.8 Toxic liver disease with other disorders of liver	0.000	0.988	0.012
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.988	0.012
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.988	0.012
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.988	0.012
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.988	0.012
K71.2 Toxic liver disease with acute hepatitis	0.000	0.988	0.012
K74.5 Biliary cirrhosis, unspecified	0.000	0.988	0.012
K82.8 Other specified diseases of gallbladder	0.000	0.988	0.012
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.012	0.988	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.988	0.012
K83 Other diseases of biliary tract	0.000	0.988	0.012
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.988	0.012
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.989	0.011
K74.6 Other and unspecified cirrhosis of liver	0.000	0.989	0.011
F07.2 Postconcussional syndrome	0.011	0.989	0.000
M35 Other systemic involvement of connective tissue	0.000	0.989	0.011
F05 Delirium, not induced by alcohol and other psychoactive substances	0.011	0.989	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.011	0.989	0.000
K74.1 Hepatic sclerosis	0.000	0.989	0.011
K71.0 Toxic liver disease with cholestasis	0.000	0.989	0.011
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.011	0.989	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.011	0.989	0.000
F07.1 Postencephalitic syndrome	0.011	0.989	0.000
K70 Alcoholic liver disease	0.000	0.989	0.011
F02.3 Dementia in Parkinson's disease	0.011	0.989	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.989	0.010
D73.0 Hyposplenism	0.010	0.990	0.000
F02.0 Dementia in Pick's disease	0.010	0.990	0.000
K72.9 Hepatic failure, unspecified	0.000	0.990	0.010
K75 Other inflammatory liver diseases	0.000	0.990	0.010
Z03.3 Observation for suspected nervous system disorder	0.000	0.990	0.010
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.010	0.990	0.000
F02.2 Dementia in Huntington's disease	0.010	0.990	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.010	0.990	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.990	0.010
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.000	0.990	0.010
N30.8 Other cystitis	0.000	0.990	0.010
F05.0 Delirium not superimposed on dementia, so described	0.009	0.991	0.000
K52.3 Indeterminate colitis	0.000	0.991	0.009
K52.1 Toxic gastro-enteritis and colitis	0.000	0.991	0.009
M35.1 Other overlap syndromes	0.000	0.991	0.009
F05.1 Delirium superimposed on dementia	0.009	0.991	0.000
F01 Vascular dementia	0.009	0.991	0.000
N30.0 Acute cystitis	0.000	0.991	0.009
K83.2 Perforation of bile duct	0.000	0.991	0.008
K83.5 Biliary cyst	0.000	0.991	0.008
K66 Other disorders of peritoneum	0.000	0.991	0.009
F06.2 Organic delusional [schizophrenia-like] disorder	0.008	0.992	0.000
K70.0 Alcoholic fatty liver	0.000	0.992	0.008
M35.2 Behcet's disease	0.000	0.992	0.008
F06.7 Mild cognitive disorder	0.008	0.992	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.992	0.008
K70.4 Alcoholic hepatic failure	0.000	0.992	0.008
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.992	0.008
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.008	0.992	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.992	0.008
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.992	0.008
M35.5 Multifocal fibrosclerosis	0.000	0.992	0.008
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.992	0.008
F06.6 Organic emotionally labile [asthenic] disorder	0.008	0.992	0.000
F06.5 Organic dissociative disorder	0.008	0.992	0.000
F06.4 Organic anxiety disorder	0.008	0.992	0.000
F06.3 Organic mood [affective] disorders	0.008	0.992	0.000
F06.1 Organic catatonic disorder	0.008	0.992	0.000
F06.0 Organic hallucinosis	0.008	0.992	0.000
M35.7 Hypermobility syndrome	0.000	0.992	0.008
K70.9 Alcoholic liver disease, unspecified	0.000	0.992	0.008
N30.3 Trigonitis	0.000	0.992	0.008
N30 Cystitis	0.000	0.992	0.008
K51.8 Other ulcerative colitis	0.000	0.992	0.008
K83.4 Spasm of sphincter of Oddi	0.000	0.992	0.008
K75.2 Nonspecific reactive hepatitis	0.000	0.992	0.008
K75.1 Phlebitis of portal vein	0.000	0.992	0.008
K83.3 Fistula of bile duct	0.000	0.992	0.007
M47.8 Other spondylosis	0.000	0.992	0.008
K75.9 Inflammatory liver disease, unspecified	0.000	0.992	0.008
C18.9 Colon, unspecified	0.008	0.992	0.000
M47.89 Other spondylosis (Site unspecified)	0.000	0.993	0.007
Z90.3 Acquired absence of part of stomach	0.000	0.993	0.007
M47.86 Other spondylosis (Lumbar region)	0.000	0.993	0.007
F05.8 Other delirium	0.007	0.993	0.000
K40-K46 Hernia	0.000	0.993	0.007
K75.4 Autoimmune hepatitis	0.000	0.993	0.007
N30.4 Irradiation cystitis	0.000	0.993	0.007
Q63.0 Accessory kidney	0.000	0.993	0.007
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.993	0.007
K42 Umbilical hernia	0.000	0.993	0.007
F01.8 Other vascular dementia	0.006	0.993	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.006	0.993	0.000
F01.2 Subcortical vascular dementia	0.006	0.993	0.000
F01.1 Multi-infarct dementia	0.006	0.993	0.000
F01.0 Vascular dementia of acute onset	0.006	0.993	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.993	0.007
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.006	0.993	0.000
K42.9 Umbilical hernia without obstruction or gangrene	0.000	0.993	0.007
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.994	0.006
K45 Other abdominal hernia	0.000	0.994	0.006
K83.9 Disease of biliary tract, unspecified	0.000	0.994	0.006
M47.84 Other spondylosis (Thoracic region)	0.000	0.994	0.006
K75.0 Abscess of liver	0.000	0.994	0.006
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.994	0.006
D73 Diseases of spleen	0.006	0.994	0.000
K66.9 Disorder of peritoneum, unspecified	0.000	0.994	0.006
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.000	0.994	0.006
K66.1 Haemoperitoneum	0.000	0.994	0.006
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.994	0.006
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.994	0.006
K70.3 Alcoholic cirrhosis of liver	0.000	0.994	0.006
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.994	0.006
K70.1 Alcoholic hepatitis	0.000	0.995	0.005
H02.3 Blepharochalasis	0.000	0.995	0.005
H02.6 Xanthelasma of eyelid	0.000	0.995	0.005
K66.8 Other specified disorders of peritoneum	0.000	0.995	0.005
D73.4 Cyst of spleen	0.005	0.995	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.005	0.995	0.000
K42.1 Umbilical hernia with gangrene	0.000	0.995	0.005
K42.0 Umbilical hernia with obstruction, without gangrene	0.000	0.995	0.005
K52.8 Other specified non-infective gastro-enteritis and colitis	0.000	0.995	0.005
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.995	0.005
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.995	0.005
D73.9 Disease of spleen, unspecified	0.005	0.995	0.000
K55-K64 Other diseases of intestines	0.000	0.995	0.005
F05.9 Delirium, unspecified	0.005	0.995	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.995	0.005
K45.1 Other specified abdominal hernia with gangrene	0.000	0.995	0.005
H02.5 Other disorders affecting eyelid function	0.000	0.995	0.005
R30.0 Dysuria	0.000	0.995	0.005
K62 Other diseases of anus and rectum	0.000	0.995	0.005
M50.3 Other cervical disk degeneration	0.000	0.995	0.005
D73.3 Abscess of spleen	0.004	0.995	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.995	0.005
K62.7 Radiation proctitis	0.000	0.995	0.005
D73.2 Chronic congestive splenomegaly	0.004	0.995	0.000
K62.6 Ulcer of anus and rectum	0.000	0.995	0.005
D73.1 Hypersplenism	0.004	0.996	0.000
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.996	0.004
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.000	0.996	0.004
S80-S89 Injuries to the knee and lower leg	0.000	0.996	0.004
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.996	0.004
M47.82 Other spondylosis (Cervical region)	0.000	0.996	0.004
K90-K93 Other diseases of the digestive system	0.000	0.996	0.004
D73.8 Other diseases of spleen	0.004	0.996	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.996	0.004
K35-K38 Diseases of appendix	0.000	0.996	0.004
D73.5 Infarction of spleen	0.004	0.996	0.000
S72.00 Fracture of neck of femur (closed)	0.004	0.996	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.996	0.004
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.004	0.996	0.000
K46 Unspecified abdominal hernia	0.000	0.996	0.004
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
K62.2 Anal prolapse	0.000	0.996	0.004
Q63 Other congenital malformations of kidney	0.000	0.996	0.004
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.996	0.004
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.996	0.004
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.996	0.004
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
S89.8 Other specified injuries of lower leg	0.000	0.996	0.004
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
N30.2 Other chronic cystitis	0.000	0.996	0.004
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.996	0.004
F01.9 Vascular dementia, unspecified	0.004	0.996	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.996	0.004
T39.0 Salicylates	0.000	0.996	0.004
S89 Other and unspecified injuries of lower leg	0.000	0.996	0.004
Z53.0 Procedure not carried out because of contraindication	0.000	0.996	0.004
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.996	0.004
A87.9 Viral meningitis, unspecified	0.000	0.996	0.004
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.996	0.004
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.004	0.996	0.000
M88.9 Paget's disease of bone, unspecified	0.004	0.996	0.000
H02 Other disorders of eyelid	0.000	0.996	0.004
N30.1 Interstitial cystitis (chronic)	0.000	0.996	0.003
Q63.1 Lobulated, fused and horseshoe kidney	0.000	0.996	0.003
K41 Femoral hernia	0.000	0.996	0.003
I89.0 Lymphoedema, not elsewhere classified	0.000	0.997	0.003
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.997	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.997	0.003
K83.1 Obstruction of bile duct	0.000	0.997	0.003
S88 Traumatic amputation of lower leg	0.000	0.997	0.003
S87 Crushing injury of lower leg	0.000	0.997	0.003
S85 Injury of blood vessels at lower leg level	0.000	0.997	0.003
S84 Injury of nerves at lower leg level	0.000	0.997	0.003
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.997	0.003
R63.0 Anorexia	0.000	0.997	0.003
S86 Injury of muscle and tendon at lower leg level	0.000	0.997	0.003
S80.0 Contusion of knee	0.000	0.997	0.003
K43 Ventral hernia	0.000	0.997	0.003
K93 Disorders of other digestive organs in diseases classified elsewhere	0.000	0.997	0.003
S80 Superficial injury of lower leg	0.000	0.997	0.003
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.997	0.003
D18.0 Haemangioma, any site	0.000	0.997	0.003
K46.1 Unspecified abdominal hernia with gangrene	0.000	0.997	0.003
Q63.2 Ectopic kidney	0.000	0.997	0.003
Q63.3 Hyperplastic and giant kidney	0.000	0.997	0.003
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.000	0.997	0.003
S82.10 Fracture of upper end of tibia (closed)	0.000	0.997	0.003
K64.9 Haemorrhoids, unspecified	0.000	0.997	0.003
K64.8 Other specified haemorrhoids	0.000	0.997	0.003
K64.5 Perianal venous thrombosis	0.000	0.997	0.003
K64.4 Residual haemorrhoidal skin tags	0.000	0.997	0.003
K64.3 Fourth degree haemorrhoids	0.000	0.997	0.003
K64.2 Third degree haemorrhoids	0.000	0.997	0.003
K64.1 Second degree haemorrhoids	0.000	0.997	0.003
K64.0 First degree haemorrhoids	0.000	0.997	0.003
Q63.9 Congenital malformation of kidney, unspecified	0.000	0.997	0.003
K83.8 Other specified diseases of biliary tract	0.000	0.997	0.003
S89.7 Multiple injuries of lower leg	0.000	0.997	0.003
S89.1 Other specified injuries of lower leg	0.000	0.997	0.003
S89.0 Multiple injuries of lower leg	0.000	0.997	0.003
M50.2 Other cervical disk displacement	0.000	0.997	0.003
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
Q63.8 Other specified congenital malformations of kidney	0.000	0.997	0.003
H02.0 Entropion and trichiasis of eyelid	0.000	0.997	0.003
H02.2 Lagophthalmos	0.000	0.997	0.003
S81 Open wound of lower leg	0.000	0.997	0.003
K57 Diverticular disease of intestine	0.000	0.997	0.003
I50.1 Left ventricular failure	0.003	0.997	0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.997	0.003
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.997	0.003
M88.98 Paget's disease of bone, unspecified (Other)	0.003	0.997	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.003	0.997	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.003	0.997	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.003	0.997	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.003	0.997	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.003	0.997	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.997	0.003
N36.8 Other specified disorders of urethra	0.000	0.997	0.003
S81.8 Open wound of other parts of lower leg	0.000	0.997	0.003
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.997	0.003
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.997	0.003
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.997	0.003
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.003	0.997	0.000
C48.2 Peritoneum, unspecified	0.003	0.997	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.997	0.003
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.997	0.003
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.997	0.003
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
S51.0 Open wound of elbow	0.003	0.997	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.997	0.003
K37 Unspecified appendicitis	0.000	0.997	0.003
M35.0 Sicca syndrome [Sjogren]	0.000	0.997	0.003
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.997	0.003
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.997	0.003
Y56.3 Emollients, demulcents and protectants	0.003	0.997	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.003	0.997	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.997	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.997	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.997	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.997	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.997	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.997	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.997	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.997	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.997	0.002
S85.5 Injury of popliteal vein	0.000	0.997	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.997	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.997	0.002
S85.2 Injury of peroneal artery	0.000	0.997	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.997	0.002
S85.0 Injury of popliteal artery	0.000	0.997	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.997	0.002
S87.0 Crushing injury of knee	0.000	0.997	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.997	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.997	0.002
S88.0 Traumatic amputation at knee level	0.000	0.997	0.002
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.000	0.997	0.003
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.997	0.003
Z93.1 Gastrostomy status	0.000	0.997	0.003
S86.0 Injury of Achilles tendon	0.000	0.997	0.002
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.997	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.997	0.002
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
C48.0 Retroperitoneum	0.003	0.997	0.000
F50.0 Anorexia nervosa	0.003	0.997	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.997	0.002
J40 Bronchitis, not specified as acute or chronic	0.000	0.997	0.003
K43.7 Other and unspecified ventral hernia with gangrene	0.000	0.997	0.002
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.000	0.997	0.002
K43.5 Parastomal hernia without obstruction or gangrene	0.000	0.997	0.002
K43.4 Parastomal hernia with gangrene	0.000	0.997	0.002
K43.3 Parastomal hernia with obstruction, without gangrene	0.000	0.997	0.002
K43.2 Incisional hernia without obstruction or gangrene	0.000	0.997	0.002
K43.1 Ventral hernia with gangrene	0.000	0.997	0.002
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.000	0.997	0.002
K93.1 Megacolon in Chagas' disease	0.000	0.997	0.002
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.000	0.997	0.002
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.997	0.003
N30-N39 Other diseases of urinary system	0.000	0.997	0.003
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.000	0.997	0.002
T39.2 Pyrazolone derivatives	0.000	0.997	0.002
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.997	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.997	0.002
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.997	0.002
K62.3 Rectal prolapse	0.000	0.998	0.002
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.998	0.002
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.998	0.002
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.998	0.002
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.998	0.002
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.998	0.002
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.998	0.002
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.998	0.002
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.998	0.002
Z83.3 Family history of diabetes mellitus	0.000	0.998	0.002
M50 Cervical disk disorders	0.000	0.998	0.002
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.002
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T46.1 Calcium-channel blockers	0.000	0.998	0.002
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.002	0.998	0.000
R30 Pain associated with micturition	0.000	0.998	0.002
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.998	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
Z93.5 Cystostomy status	0.000	0.998	0.002
C48.1 Specified parts of peritoneum	0.002	0.998	0.000
K44 Diaphragmatic hernia	0.000	0.998	0.002
H04.2 Epiphora	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.998	0.002
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
T46.7 Peripheral vasodilators	0.000	0.998	0.002
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
M75.4 Impingement syndrome of shoulder	0.000	0.998	0.002
Y56.9 Topical agent, unspecified	0.002	0.998	0.000
Y56.8 Other topical agents	0.002	0.998	0.000
Y56.7 Dental drugs, topically applied	0.002	0.998	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
Y56.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
Y56.2 Local astringents and local detergents	0.002	0.998	0.000
Y56.1 Antipruritics	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.000	0.998	0.002
K62.8 Other specified diseases of anus and rectum	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.002
N36 Other disorders of urethra	0.000	0.998	0.002
K31.8 Other specified diseases of stomach and duodenum	0.000	0.998	0.002
T43.2 Other and unspecified antidepressants	0.000	0.998	0.002
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
N37 Urethral disorders in diseases classified elsewhere	0.000	0.998	0.002
N33 Bladder disorders in diseases classified elsewhere	0.000	0.998	0.002
K12.2 Cellulitis and abscess of mouth	0.000	0.998	0.002
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.998	0.002
M67.8 Other specified disorders of synovium and tendon	0.002	0.998	0.000
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.002	0.998	0.000
N34 Urethritis and urethral syndrome	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.998	0.002
F50 Eating disorders	0.002	0.998	0.000
K62.9 Disease of anus and rectum, unspecified	0.000	0.998	0.002
S82.40 Fracture of fibula alone (closed)	0.000	0.998	0.002
C79.9 Secondary malignant neoplasm, unspecified site	0.002	0.998	0.000
M50.8 Other cervical disk disorders	0.000	0.998	0.002
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.002	0.998	0.000
K12.0 Recurrent oral aphthae	0.000	0.998	0.002
A87 Viral meningitis	0.000	0.998	0.002
M05 Seropositive rheumatoid arthritis	0.000	0.998	0.002
S72.0 Fracture of neck of femur	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.998	0.002
R23.1 Pallor	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations