TreeWAS – Variant ID: rs10821944

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.000	0.000	1.000
E03 Other hypothyroidism	0.000	0.778	0.222
E03.5 Myxoedema coma	0.000	0.840	0.159
E03.4 Atrophy of thyroid (acquired)	0.000	0.840	0.159
E03.3 Postinfectious hypothyroidism	0.000	0.840	0.159
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.849	0.150
E03.1 Congenital hypothyroidism without goitre	0.001	0.870	0.129
E00-E07 Disorders of thyroid gland	0.000	0.879	0.121
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.881	0.119
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.001	0.888	0.111
E05.9 Thyrotoxicosis, unspecified	0.000	0.891	0.109
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.892	0.108
E03.8 Other specified hypothyroidism	0.001	0.895	0.104
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.910	0.090
E05.8 Other thyrotoxicosis	0.000	0.910	0.090
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.913	0.087
E00 Congenital iodine-deficiency syndrome	0.000	0.913	0.087
E05.5 Thyroid crisis or storm	0.000	0.915	0.085
E05.4 Thyrotoxicosis factitia	0.000	0.915	0.085
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.915	0.085
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.916	0.083
M48.06 Spinal stenosis (Lumbar region)	0.079	0.921	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.924	0.076
E06 Thyroiditis	0.000	0.929	0.071
E07 Other disorders of thyroid	0.000	0.930	0.070
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.937	0.062
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.937	0.062
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.937	0.062
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.937	0.062
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.937	0.062
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.937	0.062
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.937	0.062
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.937	0.062
E04 Other non-toxic goitre	0.000	0.948	0.052
E06.1 Subacute thyroiditis	0.000	0.948	0.051
E06.4 Drug-induced thyroiditis	0.000	0.949	0.051
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.949	0.051
E06.0 Acute thyroiditis	0.000	0.949	0.051
E07.1 Dyshormogenetic goitre	0.000	0.949	0.051
E07.0 Hypersecretion of calcitonin	0.000	0.949	0.051
E06.5 Other chronic thyroiditis	0.000	0.951	0.049
E06.3 Autoimmune thyroiditis	0.000	0.955	0.045
E06.9 Thyroiditis, unspecified	0.000	0.955	0.044
E07.8 Other specified disorders of thyroid	0.000	0.956	0.044
E07.9 Disorder of thyroid, unspecified	0.000	0.957	0.043
E04.2 Non-toxic multinodular goitre	0.000	0.961	0.039
E04.8 Other specified non-toxic goitre	0.000	0.963	0.037
E04.1 Non-toxic single thyroid nodule	0.000	0.965	0.035
M48.0 Spinal stenosis	0.032	0.968	0.000
M48.02 Spinal stenosis (Cervical region)	0.030	0.970	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.972	0.028
M48.04 Spinal stenosis (Thoracic region)	0.024	0.976	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.023	0.977	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.023	0.977	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.023	0.977	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.023	0.977	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.977	0.022
T43.2 Other and unspecified antidepressants	0.020	0.980	0.000
M48 Other spondylopathies	0.020	0.980	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.020	0.980	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.018	0.982	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.016	0.983	0.000
M48.9 Spondylopathy, unspecified	0.016	0.984	0.000
M48.8 Other specified spondylopathies	0.016	0.984	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.016	0.984	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.015	0.985	0.000
G35 Multiple sclerosis	0.000	0.985	0.015
M48.4 Fatigue fracture of vertebra	0.014	0.985	0.000
M48.3 Traumatic spondylopathy	0.014	0.985	0.000
M48.2 Kissing spine	0.014	0.985	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.014	0.985	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.014	0.986	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.014	0.986	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.013	0.987	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.013	0.987	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.013	0.987	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.013	0.987	0.000
C02.9 Tongue, unspecified	0.013	0.987	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.013	0.987	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.012	0.987	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.012	0.987	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.012	0.988	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.012	0.988	0.000
T43.6 Psychostimulants with abuse potential	0.012	0.988	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.012	0.988	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.012	0.988	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.012	0.988	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.012	0.988	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.012	0.988	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.012	0.988	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.012	0.988	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.012	0.988	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.012	0.988	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.012	0.988	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.012	0.988	0.000
C02.1 Border of tongue	0.012	0.988	0.000
T43.9 Psychotropic drug, unspecified	0.012	0.988	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.012	0.988	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.012	0.988	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.012	0.988	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.012	0.988	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.012	0.988	0.000
C01 Malignant neoplasm of base of tongue	0.012	0.988	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.012	0.988	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.011	0.988	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.011	0.988	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.011	0.989	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.011	0.989	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.011	0.989	0.000
H52.3 Anisometropia and aniseikonia	0.011	0.989	0.000
C13 Malignant neoplasm of hypopharynx	0.011	0.989	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.010	0.989	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.010	0.989	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.010	0.989	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.010	0.989	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.010	0.989	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.010	0.989	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.010	0.989	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.010	0.989	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.010	0.989	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.010	0.989	0.000
M48.29 Kissing spine (Site unspecified)	0.010	0.989	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.010	0.989	0.000
M48.27 Kissing spine (Lumbosacral region)	0.010	0.989	0.000
M48.26 Kissing spine (Lumbar region)	0.010	0.989	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.010	0.989	0.000
M48.24 Kissing spine (Thoracic region)	0.010	0.989	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.010	0.989	0.000
M48.22 Kissing spine (Cervical region)	0.010	0.989	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.010	0.989	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.010	0.989	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.010	0.989	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.010	0.989	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.010	0.989	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.010	0.989	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.010	0.989	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.010	0.989	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.010	0.989	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.010	0.989	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.010	0.989	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.010	0.989	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.010	0.989	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.010	0.989	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.010	0.989	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.010	0.989	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.010	0.989	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.010	0.989	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.010	0.989	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.010	0.989	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.010	0.989	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.010	0.989	0.000
C03 Malignant neoplasm of gum	0.011	0.989	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.010	0.989	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.010	0.989	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.010	0.989	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.010	0.989	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.010	0.989	0.000
C00 Malignant neoplasm of lip	0.010	0.989	0.000
C14.0 Pharynx, unspecified	0.010	0.989	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.010	0.990	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.010	0.990	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.010	0.990	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.010	0.990	0.000
C05 Malignant neoplasm of palate	0.010	0.990	0.000
C02.4 Lingual tonsil	0.010	0.990	0.000
C10 Malignant neoplasm of oropharynx	0.010	0.990	0.000
C04 Malignant neoplasm of floor of mouth	0.010	0.990	0.000
H52.1 Myopia	0.010	0.990	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.010	0.990	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.010	0.990	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.010	0.990	0.000
C08.9 Major salivary gland, unspecified	0.010	0.990	0.000
C02.8 Overlapping lesion of tongue	0.010	0.990	0.000
C02.0 Dorsal surface of tongue	0.010	0.990	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.009	0.990	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.009	0.991	0.000
H52 Disorders of refraction and accommodation	0.009	0.991	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.009	0.991	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.009	0.991	0.000
C12 Malignant neoplasm of pyriform sinus	0.009	0.991	0.000
C02.2 Ventral surface of tongue	0.009	0.991	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.009	0.991	0.000
C08.0 Submandibular gland	0.009	0.991	0.000
C13.0 Postcricoid region	0.009	0.991	0.000
T50.8 Diagnostic agents	0.009	0.991	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.009	0.991	0.000
C13.9 Hypopharynx, unspecified	0.009	0.991	0.000
C11 Malignant neoplasm of nasopharynx	0.009	0.991	0.000
M35.3 Polymyalgia rheumatica	0.000	0.991	0.009
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.009	0.991	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.009	0.991	0.000
C03.0 Upper gum	0.009	0.991	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.009	0.991	0.000
C09 Malignant neoplasm of tonsil	0.009	0.991	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.009	0.991	0.000
T50.7 Analeptics and opioid receptor antagonists	0.008	0.991	0.000
T50.5 Appetite depressants	0.008	0.991	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.008	0.991	0.000
T50.0 Mineralocorticoids and their antagonists	0.008	0.991	0.000
C14.2 Waldeyer's ring	0.008	0.991	0.000
T50.4 Drugs affecting uric acid metabolism	0.008	0.991	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.008	0.991	0.000
J69.0 Pneumonitis due to food and vomit	0.008	0.992	0.000
C00.9 Lip, unspecified	0.008	0.992	0.000
C03.9 Gum, unspecified	0.008	0.992	0.000
T50.1 Loop [high-ceiling] diuretics	0.008	0.992	0.000
C08.8 Overlapping lesion of major salivary glands	0.008	0.992	0.000
C08.1 Sublingual gland	0.008	0.992	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
C00.1 External lower lip	0.008	0.992	0.000
C03.1 Lower gum	0.008	0.992	0.000
C05.1 Soft palate	0.008	0.992	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.008	0.992	0.000
C10.9 Oropharynx, unspecified	0.008	0.992	0.000
C00.0 External upper lip	0.008	0.992	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.008	0.992	0.000
T42.1 Iminostilbenes	0.008	0.992	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.008	0.992	0.000
C13.8 Overlapping lesion of hypopharynx	0.008	0.992	0.000
C13.2 Posterior wall of hypopharynx	0.008	0.992	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.008	0.992	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.008	0.992	0.000
C05.9 Palate, unspecified	0.008	0.992	0.000
M35 Other systemic involvement of connective tissue	0.000	0.992	0.008
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.008	0.992	0.000
C04.9 Floor of mouth, unspecified	0.008	0.992	0.000
T46.1 Calcium-channel blockers	0.008	0.992	0.000
H52.0 Hypermetropia	0.008	0.992	0.000
C00.8 Overlapping lesion of lip	0.008	0.992	0.000
C00.6 Commissure of lip	0.008	0.992	0.000
C00.5 Lip, unspecified, inner aspect	0.008	0.992	0.000
C00.4 Lower lip, inner aspect	0.008	0.992	0.000
C00.3 Upper lip, inner aspect	0.008	0.992	0.000
C00.2 External lip, unspecified	0.008	0.992	0.000
M35.0 Sicca syndrome [Sjogren]	0.000	0.992	0.008
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.008	0.992	0.000
T42.3 Barbiturates	0.008	0.992	0.000
C04.0 Anterior floor of mouth	0.008	0.992	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.008	0.992	0.000
T46.7 Peripheral vasodilators	0.008	0.992	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.008	0.992	0.000
L72.1 Trichilemmal cyst	0.000	0.992	0.008
T36 Poisoning by systemic antibiotics	0.008	0.992	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.007	0.992	0.000
T42.2 Succinimides and oxazolidinediones	0.007	0.992	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.007	0.992	0.000
C05.8 Overlapping lesion of palate	0.007	0.992	0.000
C05.2 Uvula	0.007	0.992	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.007	0.992	0.000
C10.8 Overlapping lesion of oropharynx	0.007	0.992	0.000
C10.4 Branchial cleft	0.007	0.992	0.000
C10.3 Posterior wall of oropharynx	0.007	0.992	0.000
C10.2 Lateral wall of oropharynx	0.007	0.992	0.000
C10.1 Anterior surface of epiglottis	0.007	0.992	0.000
C10.0 Vallecula	0.007	0.992	0.000
C04.8 Overlapping lesion of floor of mouth	0.007	0.993	0.000
C04.1 Lateral floor of mouth	0.007	0.993	0.000
T38.0 Glucocorticoids and synthetic analogues	0.007	0.993	0.000
T41.2 Other and unspecified general anaesthetics	0.007	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.007	0.993	0.000
H52.4 Presbyopia	0.007	0.993	0.000
M35.7 Hypermobility syndrome	0.000	0.993	0.007
C05.0 Hard palate	0.007	0.993	0.000
T38.9 Other and unspecified hormone antagonists	0.007	0.993	0.000
T38.7 Androgens and anabolic congeners	0.007	0.993	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.007	0.993	0.000
T38.5 Other oestrogens and progestogens	0.007	0.993	0.000
T38.4 Oral contraceptives	0.007	0.993	0.000
T38.2 Antithyroid drugs	0.007	0.993	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.007	0.993	0.000
H52.6 Other disorders of refraction	0.007	0.993	0.000
H52.5 Disorders of accommodation	0.007	0.993	0.000
T47.6 Antidiarrhoeal drugs	0.007	0.993	0.000
T41.5 Therapeutic gases	0.007	0.993	0.000
T41.4 Anaesthetic, unspecified	0.007	0.993	0.000
T41.3 Local anaesthetics	0.007	0.993	0.000
T41.1 Intravenous anaesthetics	0.007	0.993	0.000
T41.0 Inhaled anaesthetics	0.007	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
C09.0 Tonsillar fossa	0.007	0.993	0.000
T39.0 Salicylates	0.007	0.993	0.000
T42.0 Hydantoin derivatives	0.007	0.993	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.007	0.993	0.000
T38.1 Thyroid hormones and substitutes	0.007	0.993	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.007	0.993	0.000
M48.09 Spinal stenosis (Site unspecified)	0.006	0.993	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.007	0.993	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.993	0.000
C11.8 Overlapping lesion of nasopharynx	0.006	0.993	0.000
C11.3 Anterior wall of nasopharynx	0.006	0.993	0.000
C11.2 Lateral wall of nasopharynx	0.006	0.993	0.000
C11.0 Superior wall of nasopharynx	0.006	0.993	0.000
M35.8 Other specified systemic involvement of connective tissue	0.000	0.993	0.006
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.006	0.993	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.006	0.993	0.000
T37.5 Antiviral drugs	0.006	0.993	0.000
T37.4 Anthelminthics	0.006	0.993	0.000
T37.3 Other antiprotozoal drugs	0.006	0.993	0.000
T37.1 Antimycobacterial drugs	0.006	0.993	0.000
T37.0 Sulphonamides	0.006	0.993	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.993	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.993	0.000
T47.7 Emetics	0.006	0.993	0.000
T47.5 Digestants	0.006	0.993	0.000
T47.3 Saline and osmotic laxatives	0.006	0.993	0.000
T45.0 Antiallergic and antiemetic drugs	0.006	0.993	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.006	0.994	0.000
T45.8 Other primarily systemic and haematological agents	0.006	0.994	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.006	0.994	0.000
T45.6 Fibrinolysis-affecting drugs	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
T45.4 Iron and its compounds	0.006	0.994	0.000
T45.3 Enzymes, not elsewhere classified	0.006	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
C09.8 Overlapping lesion of tonsil	0.006	0.994	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.006	0.994	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.994	0.006
H52.2 Astigmatism	0.006	0.994	0.000
C11.1 Posterior wall of nasopharynx	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
T42.4 Benzodiazepines	0.006	0.994	0.000
N23 Unspecified renal colic	0.006	0.994	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.006	0.994	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.006	0.994	0.000
T48.5 Anti-common-cold drugs	0.006	0.994	0.000
I63.8 Other cerebral infarction	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
M35.1 Other overlap syndromes	0.000	0.994	0.006
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.006	0.994	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.994	0.006
T36.8 Other systemic antibiotics	0.006	0.994	0.000
T49.9 Topical agent, unspecified	0.006	0.994	0.000
T49.8 Other topical agents	0.006	0.994	0.000
T49.7 Dental drugs, topically applied	0.006	0.994	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.006	0.994	0.000
T49.5 Ophthalmological drugs and preparations	0.006	0.994	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.006	0.994	0.000
T49.3 Emollients, demulcents and protectants	0.006	0.994	0.000
T49.2 Local astringents and local detergents	0.006	0.994	0.000
T49.1 Antipruritics	0.006	0.994	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.994	0.006
C11.9 Nasopharynx, unspecified	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.000	0.994	0.006
M35.6 Relapsing panniculitis [Weber-Christian]	0.000	0.994	0.006
M35.5 Multifocal fibrosclerosis	0.000	0.994	0.006
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.006	0.994	0.000
T48.4 Expectorants	0.006	0.994	0.000
T48.3 Antitussives	0.006	0.994	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.006	0.994	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.006	0.994	0.000
T48.0 Oxytocic drugs	0.006	0.994	0.000
K74.0 Hepatic fibrosis	0.000	0.994	0.006
C07 Malignant neoplasm of parotid gland	0.006	0.994	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.000	0.994	0.006
M35.2 Behcet's disease	0.000	0.994	0.006
T36.9 Systemic antibiotic, unspecified	0.006	0.994	0.000
T36.7 Antifungal antibiotics, systemically used	0.006	0.994	0.000
T36.6 Rifamycins	0.006	0.994	0.000
T36.5 Aminoglycosides	0.006	0.994	0.000
T36.2 Chloramphenicol group	0.006	0.994	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.006	0.994	0.000
C06.2 Retromolar area	0.006	0.994	0.000
T47.4 Other laxatives	0.005	0.994	0.000
T47.2 Stimulant laxatives	0.005	0.994	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.005	0.994	0.000
C06.1 Vestibule of mouth	0.005	0.994	0.000
T36.4 Tetracyclines	0.005	0.994	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.994	0.006
K74.5 Biliary cirrhosis, unspecified	0.000	0.995	0.005
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
K74.3 Primary biliary cirrhosis	0.000	0.995	0.005
T36.0 Penicillins	0.005	0.995	0.000
H52.7 Disorder of refraction, unspecified	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
J69 Pneumonitis due to solids and liquids	0.005	0.995	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.995	0.005
K74.1 Hepatic sclerosis	0.000	0.995	0.005
C09.9 Tonsil, unspecified	0.005	0.995	0.000
C06.9 Mouth, unspecified	0.004	0.995	0.000
C06.0 Cheek mucosa	0.004	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.995	0.005
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.995	0.005
K74.4 Secondary biliary cirrhosis	0.000	0.995	0.004
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.995	0.004
D41.4 Bladder	0.005	0.995	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.995	0.005
T48.6 Antiasthmatics, not elsewhere classified	0.004	0.995	0.001
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.000	0.995	0.004
O26.8 Other specified pregnancy-related conditions	0.000	0.996	0.004
C83.0 Small cell (diffuse)	0.000	0.996	0.004
J69.8 Pneumonitis due to other solids and liquids	0.004	0.996	0.000
G36 Other acute disseminated demyelination	0.000	0.996	0.004
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.996	0.004
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.996	0.004
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.996	0.004
I65.2 Occlusion and stenosis of carotid artery	0.004	0.996	0.000
J69.1 Pneumonitis due to oils and essences	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.996	0.004
S52.1 Fracture of upper end of radius	0.000	0.996	0.004
B02.9 Zoster without complication	0.000	0.996	0.004
E55.9 Vitamin D deficiency, unspecified	0.000	0.996	0.004
E50-E64 Other nutritional deficiencies	0.000	0.996	0.004
C83.3 Large cell (diffuse)	0.000	0.996	0.004
E65-E68 Obesity and other hyperalimentation	0.000	0.996	0.004
C83.1 Small cleaved cell (diffuse)	0.000	0.996	0.004
E55 Vitamin D deficiency	0.000	0.996	0.004
D10.3 Other and unspecified parts of mouth	0.004	0.996	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.996	0.004
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.996	0.004
O21.0 Mild hyperemesis gravidarum	0.000	0.996	0.004
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.996	0.003
E83.3 Disorders of phosphorus metabolism	0.000	0.996	0.003
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.003
C85.0 Lymphosarcoma	0.000	0.997	0.003
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
C93 Monocytic leukaemia	0.000	0.997	0.003
R63.8 Other symptoms and signs concerning food and fluid intake	0.000	0.997	0.003
G36.9 Acute disseminated demyelination, unspecified	0.000	0.997	0.003
G36.8 Other specified acute disseminated demyelination	0.000	0.997	0.003
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.997	0.003
E61 Deficiency of other nutrient elements	0.000	0.997	0.003
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.003
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.003
C83.2 Mixed small and large cell (diffuse)	0.000	0.997	0.003
C91 Lymphoid leukaemia	0.000	0.997	0.003
C93.1 Chronic monocytic leukaemia	0.000	0.997	0.003
G36.0 Neuromyelitis optica [Devic]	0.000	0.997	0.003
G37.5 Concentric sclerosis [Balo]	0.000	0.997	0.003
G37.4 Subacute necrotising myelitis	0.000	0.997	0.003
G37.2 Central pontine myelinolysis	0.000	0.997	0.003
G37.1 Central demyelination of corpus callosum	0.000	0.997	0.003
G37.0 Diffuse sclerosis	0.000	0.997	0.003
M86.9 Osteomyelitis, unspecified	0.000	0.997	0.003
C92 Myeloid leukaemia	0.000	0.997	0.003
O21 Excessive vomiting in pregnancy	0.000	0.997	0.003
L03.0 Cellulitis of finger and toe	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.003
E54 Ascorbic acid deficiency	0.000	0.997	0.003
C94 Other leukaemias of specified cell type	0.000	0.997	0.003
S52.11 Fracture of upper end of radius (open)	0.000	0.997	0.003
C91.0 Acute lymphoblastic leukaemia	0.000	0.997	0.003
T40.3 Methadone	0.003	0.997	0.000
E56 Other vitamin deficiencies	0.000	0.997	0.003
E40-E46 Malnutrition	0.000	0.997	0.003
M86.96 Osteomyelitis, unspecified (Lower leg)	0.000	0.997	0.003
Z93.2 Ileostomy status	0.000	0.997	0.003
E65 Localised adiposity	0.000	0.997	0.003
N85.2 Hypertrophy of uterus	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.997	0.003
E50 Vitamin A deficiency	0.000	0.997	0.003
E60 Dietary zinc deficiency	0.000	0.997	0.003
E59 Dietary selenium deficiency	0.000	0.997	0.003
E52 Niacin deficiency [pellagra]	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.000	0.997	0.003
E61.1 Iron deficiency	0.000	0.997	0.003
E67 Other hyperalimentation	0.000	0.997	0.003
E68 Sequelae of hyperalimentation	0.000	0.997	0.003
E55.0 Rickets, active	0.000	0.997	0.003
Z03.9 Observation for suspected disease or condition, unspecified	0.003	0.997	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
E15 Nondiabetic hypoglycaemic coma	0.000	0.997	0.003
C92.9 Myeloid leukaemia, unspecified	0.000	0.997	0.003
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
O21.9 Vomiting of pregnancy, unspecified	0.000	0.997	0.003
C95 Leukaemia of unspecified cell type	0.000	0.997	0.003
E27 Other disorders of adrenal gland	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.000	0.997	0.003
C32.0 Glottis	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.000	0.997	0.003
C92.1 Chronic myeloid leukaemia	0.000	0.997	0.003
C32 Malignant neoplasm of larynx	0.003	0.997	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.997	0.003
E51 Thiamine deficiency	0.000	0.997	0.003
O26 Maternal care for other conditions predominantly related to pregnancy	0.000	0.997	0.003
O23 Infections of genito-urinary tract in pregnancy	0.000	0.997	0.003
N92.4 Excessive bleeding in the premenopausal period	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.997	0.000
T40.8 Lysergide [LSD]	0.002	0.997	0.000
T40.7 Cannabis (derivatives)	0.002	0.997	0.000
T40.0 Opium	0.002	0.997	0.000
C88 Malignant immunoproliferative diseases	0.000	0.997	0.003
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.003	0.997	0.000
C32.1 Supraglottis	0.003	0.997	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.003	0.997	0.000
T40.5 Cocaine	0.002	0.997	0.000
E58 Dietary calcium deficiency	0.000	0.997	0.003
E63 Other nutritional deficiencies	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations