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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10849931
log Bayes Factor = 7.46303
Chromosome 12   position 111,753,808  (GRCh37) Explore rs10849931 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I10 Essential (primary) hypertension
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E03.9 Hypothyroidism, unspecified
0.000 0.001 0.999
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.003 0.997
E05.9 Thyrotoxicosis, unspecified
0.000 0.004 0.996
E06 Thyroiditis
0.000 0.040 0.960
E07 Other disorders of thyroid
0.000 0.041 0.959
E07.9 Disorder of thyroid, unspecified
0.000 0.065 0.935
E06.3 Autoimmune thyroiditis
0.000 0.094 0.906
E04 Other non-toxic goitre
0.000 0.117 0.883
E06.9 Thyroiditis, unspecified
0.000 0.180 0.820
I10-I15 Hypertensive diseases
0.000 0.189 0.811
E04.1 Non-toxic single thyroid nodule
0.000 0.202 0.798
E04.9 Non-toxic goitre, unspecified
0.000 0.222 0.778
I12 Hypertensive renal disease
0.000 0.237 0.763
E03.8 Other specified hypothyroidism
0.000 0.247 0.753
I12.9 Hypertensive renal disease without renal failure
0.000 0.260 0.740
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.262 0.738
E05.8 Other thyrotoxicosis
0.000 0.279 0.721
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E06.5 Other chronic thyroiditis
0.000 0.312 0.688
E06.4 Drug-induced thyroiditis
0.000 0.312 0.688
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.312 0.688
E06.1 Subacute thyroiditis
0.000 0.312 0.688
E06.0 Acute thyroiditis
0.000 0.312 0.688
E07.1 Dyshormogenetic goitre
0.000 0.312 0.688
E07.0 Hypersecretion of calcitonin
0.000 0.312 0.688
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.321 0.679
E04.0 Non-toxic diffuse goitre
0.000 0.329 0.671
E07.8 Other specified disorders of thyroid
0.000 0.355 0.645
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.362 0.638
I15 Secondary hypertension
0.000 0.364 0.636
E04.8 Other specified non-toxic goitre
0.000 0.367 0.633
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.385 0.614
I13 Hypertensive heart and renal disease
0.000 0.418 0.582
I11 Hypertensive heart disease
0.000 0.436 0.564
I15.1 Hypertension secondary to other renal disorders
0.000 0.473 0.527
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
I15.8 Other secondary hypertension
0.000 0.544 0.456
I15.2 Hypertension secondary to endocrine disorders
0.000 0.544 0.456
I15.0 Renovascular hypertension
0.000 0.544 0.456
I12.0 Hypertensive renal disease with renal failure
0.000 0.555 0.445
I15.9 Seconday hypertension, unspecified
0.000 0.571 0.429
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.583 0.417
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.583 0.417
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.583 0.417
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.583 0.417
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.584 0.416
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.628 0.372
E04.2 Non-toxic multinodular goitre
0.000 0.802 0.197
J34.2 Deviated nasal septum
0.084 0.916 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.954 0.046
I35.0 Aortic (valve) stenosis
0.000 0.954 0.046
I35 Nonrheumatic aortic valve disorders
0.000 0.954 0.046
I49.3 Ventricular premature depolarisation
0.000 0.963 0.037
I35.9 Aortic valve disorder, unspecified
0.000 0.964 0.036
I35.1 Aortic (valve) insufficiency
0.000 0.965 0.035
Chapter IX Diseases of the circulatory system
0.000 0.966 0.034
I49 Other cardiac arrhythmias
0.000 0.966 0.034
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.967 0.033
I49.0 Ventricular fibrillation and flutter
0.000 0.968 0.032
I30-I52 Other forms of heart disease
0.000 0.968 0.032
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.969 0.031
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.969 0.031
I42.9 Cardiomyopathy, unspecified
0.000 0.969 0.031
I42 Cardiomyopathy
0.000 0.969 0.031
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.970 0.030
I71 Aortic aneurysm and dissection
0.000 0.970 0.030
E16 Other disorders of pancreatic internal secretion
0.000 0.970 0.030
E16.2 Hypoglycaemia, unspecified
0.000 0.971 0.029
I35.8 Other aortic valve disorders
0.000 0.971 0.029
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.971 0.029
I49.9 Cardiac arrhythmia, unspecified
0.000 0.971 0.029
I70 Atherosclerosis
0.000 0.972 0.028
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.972 0.028
I77 Other disorders of arteries and arterioles
0.000 0.974 0.026
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.974 0.026
I78 Diseases of capillaries
0.000 0.974 0.026
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.974 0.026
Z95.1 Presence of aortocoronary bypass graft
0.000 0.974 0.026
E50-E64 Other nutritional deficiencies
0.000 0.974 0.025
I77.6 Arteritis, unspecified
0.000 0.975 0.025
I49.4 Other and unspecified premature depolarisation
0.000 0.975 0.025
Z95.4 Presence of other heart-valve replacement
0.000 0.975 0.025
I00-I02 Acute rheumatic fever
0.000 0.975 0.025
I49.2 Junctional premature depolarisation
0.000 0.975 0.025
E16.1 Other hypoglycaemia
0.000 0.976 0.024
I71.0 Dissection of aorta [any part]
0.000 0.976 0.024
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.976 0.024
I42.8 Other cardiomyopathies
0.000 0.977 0.023
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.977 0.023
I52 Other heart disorders in diseases classified elsewhere
0.000 0.977 0.023
I48 Atrial fibrillation and flutter
0.000 0.977 0.023
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.977 0.023
I41 Myocarditis in diseases classified elsewhere
0.000 0.977 0.023
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.977 0.023
I32 Pericarditis in diseases classified elsewhere
0.000 0.977 0.023
I78.1 Naevus, nonneoplastic
0.000 0.977 0.023
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.977 0.023
I33 Acute and subacute endocarditis
0.000 0.977 0.023
E15 Nondiabetic hypoglycaemic coma
0.000 0.977 0.022
I40 Acute myocarditis
0.000 0.978 0.022
I42.5 Other restrictive cardiomyopathy
0.000 0.978 0.022
I42.4 Endocardial fibroelastosis
0.000 0.978 0.022
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.978 0.022
I36 Nonrheumatic tricuspid valve disorders
0.000 0.978 0.022
I42.0 Dilated cardiomyopathy
0.000 0.978 0.022
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.978 0.022
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.978 0.022
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.978 0.022
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.978 0.021
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.978 0.021
E16.4 Abnormal secretion of gastrin
0.000 0.978 0.021
E16.3 Increased secretion of glucagon
0.000 0.978 0.021
I37 Pulmonary valve disorders
0.000 0.978 0.022
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.979 0.021
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.979 0.021
I99 Other and unspecified disorders of circulatory system
0.000 0.979 0.021
E53 Deficiency of other B group vitamins
0.000 0.979 0.021
I70.9 Generalised and unspecified atherosclerosis
0.000 0.979 0.021
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.979 0.021
Z95.2 Presence of prosthetic heart valve
0.000 0.979 0.021
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.980 0.020
I70.1 Atherosclerosis of renal artery
0.000 0.980 0.020
I49.1 Atrial premature depolarisation
0.000 0.980 0.020
I77.1 Stricture of artery
0.000 0.980 0.020
I70.8 Atherosclerosis of other arteries
0.000 0.980 0.020
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.980 0.020
E61 Deficiency of other nutrient elements
0.000 0.981 0.019
I77.2 Rupture of artery
0.000 0.981 0.019
I50 Heart failure
0.000 0.981 0.019
I42.6 Alcoholic cardiomyopathy
0.000 0.981 0.019
I77.5 Necrosis of artery
0.000 0.981 0.019
I77.4 Coeliac artery compression syndrome
0.000 0.981 0.019
I77.3 Arterial fibromuscular dysplasia
0.000 0.981 0.019
I50.9 Heart failure, unspecified
0.000 0.981 0.019
I47 Paroxysmal tachycardia
0.000 0.981 0.019
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.981 0.019
I77.8 Other specified disorders of arteries and arterioles
0.000 0.981 0.019
I51 Complications and ill-defined descriptions of heart disease
0.000 0.981 0.019
I78.9 Disease of capillaries, unspecified
0.000 0.981 0.019
I70.0 Atherosclerosis of aorta
0.000 0.981 0.019
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.981 0.019
E40-E46 Malnutrition
0.000 0.981 0.018
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.981 0.018
E63 Other nutritional deficiencies
0.000 0.981 0.018
E51 Thiamine deficiency
0.000 0.981 0.018
E50 Vitamin A deficiency
0.000 0.981 0.018
E60 Dietary zinc deficiency
0.000 0.981 0.018
E59 Dietary selenium deficiency
0.000 0.981 0.018
E58 Dietary calcium deficiency
0.000 0.981 0.018
E54 Ascorbic acid deficiency
0.000 0.981 0.018
E52 Niacin deficiency [pellagra]
0.000 0.981 0.018
I51.7 Cardiomegaly
0.000 0.982 0.018
I49.5 Sick sinus syndrome
0.000 0.982 0.018
I02 Rheumatic chorea
0.000 0.982 0.018
I01 Rheumatic fever with heart involvement
0.000 0.982 0.018
I00 Rheumatic fever without mention of heart involvement
0.000 0.982 0.018
I38 Endocarditis, valve unspecified
0.000 0.982 0.018
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.982 0.018
E53.8 Deficiency of other specified B group vitamins
0.000 0.982 0.018
I45 Other conduction disorders
0.000 0.982 0.018
E55 Vitamin D deficiency
0.000 0.982 0.018
E56 Other vitamin deficiencies
0.000 0.983 0.017
I77.0 Arteriovenous fistula, acquired
0.000 0.983 0.017
I42.2 Other hypertrophic cardiomyopathy
0.000 0.983 0.017
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.983 0.017
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.983 0.017
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.983 0.017
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.983 0.017
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.983 0.017
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.983 0.017
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.983 0.017
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.983 0.017
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.983 0.017
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.983 0.017
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.983 0.017
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.983 0.017
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.983 0.017
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.983 0.017
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.983 0.017
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.983 0.017
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.983 0.017
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.983 0.017
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.983 0.017
I48.4 Atypical atrial flutter
0.000 0.983 0.017
I48.3 Typical atrial flutter
0.000 0.983 0.017
I48.2 Chronic atrial fibrillation
0.000 0.983 0.017
I48.1 Persistent atrial fibrillation
0.000 0.983 0.017
I48.0 Paroxysmal atrial fibrillation
0.000 0.983 0.017
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.983 0.017
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.983 0.017
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.983 0.017
I97.1 Other functional disturbances following cardiac surgery
0.000 0.983 0.016
I33.9 Acute endocarditis, unspecified
0.000 0.984 0.016
I40.9 Acute myocarditis, unspecified
0.000 0.984 0.016
I40.8 Other acute myocarditis
0.000 0.984 0.016
I40.1 Isolated myocarditis
0.000 0.984 0.016
H40.0 Glaucoma suspect
0.016 0.984 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.984 0.016
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.984 0.016
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.984 0.016
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.984 0.016
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.984 0.016
I33.0 Acute and subacute infective endocarditis
0.000 0.984 0.016
I40.0 Infective myocarditis
0.000 0.984 0.016
I37.9 Pulmonary valve disorder, unspecified
0.000 0.984 0.016
I37.8 Other pulmonary valve disorders
0.000 0.984 0.016
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.984 0.016
I37.0 Pulmonary valve stenosis
0.000 0.984 0.016
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.984 0.015
I79.1 Aortitis in diseases classified elsewhere
0.000 0.984 0.015
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.984 0.015
Z95.3 Presence of xenogenic heart valve
0.000 0.984 0.016
I78.8 Other diseases of capillaries
0.000 0.985 0.015
E61.1 Iron deficiency
0.000 0.985 0.015
E53.1 Pyridoxine deficiency
0.000 0.985 0.015
E53.0 Riboflavin deficiency
0.000 0.985 0.015
I47.0 Reentry ventricular arrhythmia
0.000 0.985 0.015
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.985 0.015
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.985 0.015
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.985 0.015
I51.4 Myocarditis, unspecified
0.000 0.985 0.015
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.985 0.015
I26 Pulmonary embolism
0.000 0.985 0.015
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.985 0.015
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.985 0.015
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.985 0.014
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.985 0.015
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.985 0.014
E53.9 Vitamin B deficiency, unspecified
0.000 0.985 0.014
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.985 0.014
I97.0 Postcardiotomy syndrome
0.000 0.985 0.014
I74 Arterial embolism and thrombosis
0.000 0.986 0.014
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.986 0.014
I37.1 Pulmonary valve insufficiency
0.000 0.986 0.014
E61.9 Deficiency of nutrient element, unspecified
0.000 0.986 0.014
E61.8 Deficiency of other specified nutrient elements
0.000 0.986 0.014
E61.7 Deficiency of multiple nutrient elements
0.000 0.986 0.014
E61.6 Vanadium deficiency
0.000 0.986 0.014
E61.5 Molybdenum deficiency
0.000 0.986 0.014
E61.4 Chromium deficiency
0.000 0.986 0.014
E61.3 Manganese deficiency
0.000 0.986 0.014
E61.0 Copper deficiency
0.000 0.986 0.014
I45.2 Bifascicular block
0.000 0.986 0.014
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.986 0.014
I28 Other diseases of pulmonary vessels
0.000 0.986 0.014
E61.2 Magnesium deficiency
0.000 0.986 0.014
I51.5 Myocardial degeneration
0.000 0.986 0.014
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.986 0.014
I51.6 Cardiovascular disease, unspecified
0.000 0.986 0.014
I45.4 Nonspecific intraventricular block
0.000 0.986 0.014
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.986 0.014
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.986 0.013
E45 Retarded development following protein-energy malnutrition
0.000 0.986 0.013
E43 Unspecified severe protein-energy malnutrition
0.000 0.986 0.013
E42 Marasmic kwashiorkor
0.000 0.986 0.013
E41 Nutritional marasmus
0.000 0.986 0.013
E40 Kwashiorkor
0.000 0.986 0.013
E50.9 Vitamin A deficiency, unspecified
0.000 0.986 0.013
E50.8 Other manifestations of vitamin A deficiency
0.000 0.986 0.013
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.986 0.013
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.986 0.013
E50.5 Vitamin A deficiency with night blindness
0.000 0.986 0.013
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.986 0.013
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.986 0.013
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.986 0.013
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.986 0.013
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.986 0.013
E51.9 Thiamine deficiency, unspecified
0.000 0.986 0.013
E51.8 Other manifestations of thiamine deficiency
0.000 0.986 0.013
E51.2 Wernicke's encephalopathy
0.000 0.986 0.013
E51.1 Beriberi
0.000 0.986 0.013
E63.9 Nutritional deficiency, unspecified
0.000 0.986 0.013
E63.8 Other specified nutritional deficiencies
0.000 0.986 0.013
E63.1 Imbalance of constituents of food intake
0.000 0.986 0.013
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.986 0.013
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.986 0.013
E64.8 Sequelae of other nutritional deficiencies
0.000 0.986 0.013
E64.3 Sequelae of rickets
0.000 0.986 0.013
E64.2 Sequelae of vitamin C deficiency
0.000 0.986 0.013
E64.1 Sequelae of vitamin A deficiency
0.000 0.986 0.013
E64.0 Sequelae of protein-energy malnutrition
0.000 0.986 0.013
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.986 0.013
I72 Other aneurysm
0.000 0.987 0.013
I45.5 Other specified heart block
0.000 0.987 0.013
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.987 0.013
I01.8 Other acute rheumatic heart disease
0.000 0.987 0.013
I01.2 Acute rheumatic myocarditis
0.000 0.987 0.013
I01.1 Acute rheumatic endocarditis
0.000 0.987 0.013
I01.0 Acute rheumatic pericarditis
0.000 0.987 0.013
I02.9 Rheumatic chorea without heart involvement
0.000 0.987 0.013
I02.0 Rheumatic chorea with heart involvement
0.000 0.987 0.013
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.987 0.013
I45.0 Right fascicular block
0.000 0.987 0.013
I45.1 Other and unspecified right bundle-branch block
0.000 0.987 0.013
E55.0 Rickets, active
0.000 0.987 0.013
E56.9 Vitamin deficiency, unspecified
0.000 0.987 0.013
E56.8 Deficiency of other vitamins
0.000 0.987 0.013
E56.0 Deficiency of vitamin E
0.000 0.987 0.013
I74.5 Embolism and thrombosis of iliac artery
0.000 0.988 0.012
I45.6 Preexcitation syndrome
0.000 0.988 0.012
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.988 0.012
I45.8 Other specified conduction disorders
0.000 0.988 0.012
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.988 0.012
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.988 0.012
I46 Cardiac arrest
0.000 0.988 0.012
E55.9 Vitamin D deficiency, unspecified
0.000 0.988 0.012
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.988 0.012
E56.1 Deficiency of vitamin K
0.000 0.988 0.011
I47.2 Ventricular tachycardia
0.000 0.988 0.012
I30 Acute pericarditis
0.001 0.988 0.011
K57.2 Diverticular disease of large intestine with perforation and abscess
0.000 0.989 0.011
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.000 0.989 0.011
Z90.1 Acquired absence of breast(s)
0.011 0.989 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.989 0.011
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.989 0.011
I72.3 Aneurysm of iliac artery
0.000 0.989 0.011
I45.9 Conduction disorder, unspecified
0.000 0.989 0.011
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.989 0.011
D72.8 Other specified disorders of white blood cells
0.000 0.989 0.011
I28.8 Other specified diseases of pulmonary vessels
0.000 0.989 0.011
E22 Hyperfunction of pituitary gland
0.000 0.989 0.011
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.989 0.011
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.989 0.011
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.000 0.990 0.010
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.990 0.010
I28.1 Aneurysm of pulmonary artery
0.000 0.990 0.010
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.990 0.010
I31 Other diseases of pericardium
0.000 0.990 0.010
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.990 0.010
I73 Other peripheral vascular diseases
0.000 0.990 0.010
E44.1 Mild protein-energy malnutrition
0.000 0.990 0.010
E44.0 Moderate protein-energy malnutrition
0.000 0.990 0.010
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.990 0.010
I74.8 Embolism and thrombosis of other arteries
0.000 0.990 0.010
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.990 0.010
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.990 0.010
I72.2 Aneurysm of renal artery
0.000 0.990 0.010
K90.0 Coeliac disease
0.000 0.990 0.010
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.990 0.009
E28 Ovarian dysfunction
0.000 0.991 0.009
I72.0 Aneurysm of carotid artery
0.000 0.991 0.009
E65-E68 Obesity and other hyperalimentation
0.000 0.991 0.009
I72.9 Aneurysm of unspecified site
0.000 0.991 0.009
E22.1 Hyperprolactinaemia
0.000 0.991 0.009
I51.0 Cardiac septal defect, acquired
0.000 0.991 0.009
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.991 0.009
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.991 0.009
I98.0 Cardiovascular syphilis
0.000 0.991 0.009
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.991 0.009
D86.0 Sarcoidosis of lung
0.000 0.991 0.009
I46.1 Sudden cardiac death, so described
0.000 0.991 0.009
D89.2 Hypergammaglobulinaemia, unspecified
0.000 0.991 0.009
I47.1 Supraventricular tachycardia
0.000 0.991 0.009
I30.8 Other forms of acute pericarditis
0.001 0.991 0.008
I30.0 Acute nonspecific idiopathic pericarditis
0.001 0.991 0.008
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.992 0.008
E20 Hypoparathyroidism
0.000 0.992 0.008
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.992 0.008
E32 Diseases of thymus
0.000 0.992 0.008
E31 Polyglandular dysfunction
0.000 0.992 0.008
E30 Disorders of puberty, not elsewhere classified
0.000 0.992 0.008
E46 Unspecified protein-energy malnutrition
0.000 0.992 0.008
I51.9 Heart disease, unspecified
0.000 0.992 0.008
I72.1 Aneurysm of artery of upper extremity
0.000 0.992 0.008
M35.0 Sicca syndrome [Sjogren]
0.000 0.992 0.008
I72.8 Aneurysm of other specified arteries
0.000 0.992 0.008
S82.20 Fracture of shaft of tibia (closed)
0.008 0.992 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.992 0.008
E22.8 Other hyperfunction of pituitary gland
0.000 0.992 0.008
D72 Other disorders of white blood cells
0.000 0.992 0.008
E23 Hypofunction and other disorders of pituitary gland
0.000 0.992 0.008
I05-I09 Chronic rheumatic heart diseases
0.000 0.992 0.008
E25 Adrenogenital disorders
0.000 0.992 0.008
E34 Other endocrine disorders
0.000 0.992 0.008
I31.8 Other specified diseases of pericardium
0.000 0.992 0.008
I31.2 Haemopericardium, not elsewhere classified
0.000 0.992 0.008
I31.0 Chronic adhesive pericarditis
0.000 0.992 0.008
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.000 0.992 0.008
D86 Sarcoidosis
0.000 0.992 0.008
N92.0 Excessive and frequent menstruation with regular cycle
0.000 0.992 0.008
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.992 0.007
E26 Hyperaldosteronism
0.000 0.992 0.007
I31.1 Chronic constrictive pericarditis
0.000 0.992 0.007
E28.2 Polycystic ovarian syndrome
0.000 0.993 0.007
E28.3 Primary ovarian failure
0.000 0.993 0.007
I49.8 Other specified cardiac arrhythmias
0.000 0.993 0.007
Z90.7 Acquired absence of genital organ(s)
0.000 0.993 0.007
I63.8 Other cerebral infarction
0.000 0.993 0.007
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.993 0.007
I45.3 Trifascicular block
0.001 0.993 0.007
D80-D89 Certain disorders involving the immune mechanism
0.000 0.993 0.007
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.993 0.007
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.993 0.007
I63 Cerebral infarction
0.000 0.993 0.007
E28.9 Ovarian dysfunction, unspecified
0.000 0.993 0.007
E28.8 Other ovarian dysfunction
0.000 0.993 0.007
E28.1 Androgen excess
0.000 0.993 0.007
E28.0 Oestrogen excess
0.000 0.993 0.007
E67 Other hyperalimentation
0.000 0.993 0.007
E68 Sequelae of hyperalimentation
0.000 0.993 0.007
D86.9 Sarcoidosis, unspecified
0.000 0.993 0.007
D59.1 Other autoimmune haemolytic anaemias
0.000 0.993 0.007
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.993 0.007
I46.0 Cardiac arrest with successful resuscitation
0.000 0.993 0.007
I73.8 Other specified peripheral vascular diseases
0.000 0.993 0.006
E23.7 Disorder of pituitary gland, unspecified
0.000 0.993 0.007
I20-I25 Ischaemic heart diseases
0.000 0.993 0.007
I72.4 Aneurysm of artery of lower extremity
0.000 0.994 0.006
I73.0 Raynaud's syndrome
0.000 0.994 0.006
E20.9 Hypoparathyroidism, unspecified
0.000 0.994 0.006
E34.0 Carcinoid syndrome
0.000 0.994 0.006
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.994 0.006
E20.8 Other hypoparathyroidism
0.000 0.994 0.006
E20.1 Pseudohypoparathyroidism
0.000 0.994 0.006
E20.0 Idiopathic hypoparathyroidism
0.000 0.994 0.006
Z42.1 Follow-up care involving plastic surgery of breast
0.006 0.994 0.000
E30.9 Disorder of puberty, unspecified
0.000 0.994 0.006
E30.8 Other disorders of puberty
0.000 0.994 0.006
E30.1 Precocious puberty
0.000 0.994 0.006
E30.0 Delayed puberty
0.000 0.994 0.006
E31.9 Polyglandular dysfunction, unspecified
0.000 0.994 0.006
E31.8 Other polyglandular dysfunction
0.000 0.994 0.006
E31.1 Polyglandular hyperfunction
0.000 0.994 0.006
E31.0 Autoimmune polyglandular failure
0.000 0.994 0.006
E32.9 Disease of thymus, unspecified
0.000 0.994 0.006
E32.8 Other diseases of thymus
0.000 0.994 0.006
E32.1 Abscess of thymus
0.000 0.994 0.006
E32.0 Persistent hyperplasia of thymus
0.000 0.994 0.006
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.994 0.006
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.994 0.006
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.994 0.006
J34 Other disorders of nose and nasal sinuses
0.006 0.994 0.000
E23.2 Diabetes insipidus
0.000 0.994 0.006
D89.9 Disorder involving the immune mechanism, unspecified
0.000 0.994 0.006
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.994 0.006
D59 Acquired haemolytic anaemia
0.000 0.994 0.006
E27 Other disorders of adrenal gland
0.000 0.994 0.006
E27.1 Primary adrenocortical insufficiency
0.000 0.994 0.006
I30.1 Infective pericarditis
0.001 0.994 0.005
D72.9 Disorder of white blood cells, unspecified
0.000 0.994 0.006
D72.0 Genetic anomalies of leukocytes
0.000 0.994 0.006
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.994 0.006
E23.1 Drug-induced hypopituitarism
0.000 0.994 0.006
D72.1 Eosinophilia
0.000 0.994 0.006
I23 Certain current complications following acute myocardial infarction
0.000 0.994 0.006
E25.9 Adrenogenital disorder, unspecified
0.000 0.994 0.006
E25.8 Other adrenogenital disorders
0.000 0.994 0.006
E23.6 Other disorders of pituitary gland
0.000 0.994 0.006
E10-E14 Diabetes mellitus
0.000 0.994 0.006
E34.5 Androgen resistance syndrome
0.000 0.994 0.006
E34.4 Constitutional tall stature
0.000 0.994 0.006
E34.3 Short stature, not elsewhere classified
0.000 0.994 0.006
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.994 0.006
E34.1 Other hypersecretion of intestinal hormones
0.000 0.994 0.006
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.000 0.994 0.006
D89.3 Immune reconstitution syndrome
0.000 0.994 0.006
D89.0 Polyclonal hypergammaglobulinaemia
0.000 0.994 0.006
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.994 0.006
D70-D77 Other diseases of blood and blood-forming organs
0.000 0.994 0.006
D75.2 Essential thrombocytosis
0.000 0.994 0.006
E22.0 Acromegaly and pituitary gigantism
0.000 0.994 0.005
E26.9 Hyperaldosteronism, unspecified
0.000 0.994 0.005
E26.8 Other hyperaldosteronism
0.000 0.994 0.005
E26.1 Secondary hyperaldosteronism
0.000 0.994 0.005
D86.1 Sarcoidosis of lymph nodes
0.000 0.994 0.006
I23.8 Other current complications following acute myocardial infarction
0.000 0.994 0.005
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.994 0.005
D86.3 Sarcoidosis of skin
0.000 0.995 0.005
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.000 0.995 0.005
D84 Other immunodeficiencies
0.000 0.995 0.005
I06 Rheumatic aortic valve diseases
0.000 0.995 0.005
D81 Combined immunodeficiencies
0.000 0.995 0.005
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.995 0.005
E34.9 Endocrine disorder, unspecified
0.000 0.995 0.005
D55-D59 Haemolytic anaemias
0.000 0.995 0.005
E29 Testicular dysfunction
0.001 0.995 0.005
D76.3 Other histiocytosis syndromes
0.000 0.995 0.005
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.995 0.005
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.995 0.005
D83 Common variable immunodeficiency
0.000 0.995 0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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