TreeWAS – Variant ID: rs10859563

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M22 Disorders of patella	0.992	0.008	0.000
M22.4 Chondromalacia patellae	0.990	0.010	0.000
M22.8 Other disorders of patella	0.989	0.011	0.000
M20-M25 Other joint disorders	0.980	0.020	0.000
M23 Internal derangement of knee	0.977	0.023	0.000
M23.3 Other meniscus derangements	0.947	0.053	0.000
M24 Other specific joint derangements	0.941	0.059	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.940	0.060	0.000
M23.8 Other internal derangements of knee	0.916	0.084	0.000
M24.2 Disorder of ligament	0.883	0.117	0.000
M23.4 Loose body in knee	0.878	0.122	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.848	0.152	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.842	0.158	0.000
M23.5 Chronic instability of knee	0.842	0.158	0.000
M34 Systemic sclerosis	0.838	0.162	0.000
M33 Dermatopolymyositis	0.837	0.163	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.813	0.187	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.807	0.193	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.796	0.204	0.000
M22.9 Disorder of patella, unspecified	0.790	0.210	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.786	0.214	0.000
M23.0 Cystic meniscus	0.774	0.226	0.000
M24.9 Joint derangement, unspecified	0.761	0.239	0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.752	0.248	0.000
M24.5 Contracture of joint	0.750	0.250	0.000
M24.26 Disorder of ligament (Lower leg)	0.750	0.250	0.000
M23.49 Loose body in knee-Unspec lig/men	0.746	0.254	0.000
M23.87 Other internal derangements of knee (Capsular ligament)	0.742	0.258	0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.741	0.259	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.727	0.273	0.000
M33.2 Polymyositis	0.724	0.276	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.719	0.281	0.000
M22.0 Recurrent dislocation of patella	0.718	0.282	0.000
M24.23 Disorder of ligament (Forearm)	0.718	0.282	0.000
M22.1 Recurrent subluxation of patella	0.711	0.289	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.704	0.296	0.000
M23.80 Other internal derangements of knee (Multiple sites)	0.703	0.297	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.702	0.298	0.000
M24.6 Ankylosis of joint	0.700	0.300	0.000
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.700	0.300	0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.699	0.301	0.000
M23.43 Loose body in knee-Med lig/oth men	0.694	0.306	0.000
M23.41 Loose body in knee-Ant lig/hrn men	0.692	0.308	0.000
M32 Systemic lupus erythematosus	0.689	0.311	0.000
M30 Polyarteritis nodosa and related conditions	0.688	0.312	0.000
M24.28 Disorder of ligament (Other)	0.683	0.317	0.000
M23.50 Chronic instability of knee (Multiple sites)	0.680	0.320	0.000
M23.37 Other meniscus derangements-Capsular lig	0.679	0.321	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.679	0.321	0.000
M34.9 Systemic sclerosis, unspecified	0.672	0.328	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.669	0.331	0.000
M22.3 Other derangements of patella	0.669	0.331	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.666	0.333	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.663	0.337	0.000
M23.1 Discoid meniscus (congenital)	0.660	0.340	0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.657	0.343	0.000
M24.56 Contracture of joint (Lower leg)	0.652	0.348	0.000
M34.8 Other forms of systemic sclerosis	0.644	0.356	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.644	0.356	0.000
M23.40 Loose body in knee-Mult sites	0.643	0.357	0.000
M23.44 Loose body in knee-Lat lig/ant men	0.641	0.359	0.000
M35 Other systemic involvement of connective tissue	0.641	0.359	0.000
M23.9 Internal derangement of knee, unspecified	0.640	0.360	0.000
M34.0 Progressive systemic sclerosis	0.638	0.362	0.000
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.636	0.364	0.000
M24.29 Disorder of ligament (Site unspecified)	0.633	0.367	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.633	0.367	0.000
M24.22 Disorder of ligament (Upper arm)	0.633	0.367	0.000
M24.20 Disorder of ligament (Multiple sites)	0.633	0.367	0.000
M23.47 Loose body in knee-Capsular lig	0.629	0.370	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.629	0.370	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.629	0.370	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.629	0.371	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.628	0.372	0.000
M34.1 CR(E)ST syndrome	0.626	0.373	0.000
M33.1 Other dermatomyositis	0.625	0.375	0.000
M24.7 Protrusio acetabuli	0.622	0.378	0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.620	0.380	0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.620	0.380	0.000
M24.21 Disorder of ligament (Shoulder region)	0.617	0.383	0.000
M22.2 Patellofemoral disorders	0.616	0.384	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.613	0.387	0.000
M24.94 Joint derangement, unspecified (Hand)	0.613	0.387	0.000
M23.46 Loose body in knee-O/unsp lat men	0.610	0.390	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.608	0.392	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.608	0.392	0.000
M23.57 Chronic instability of knee (Capsular ligament)	0.604	0.396	0.000
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.604	0.396	0.000
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.604	0.396	0.000
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.604	0.396	0.000
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.604	0.396	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.601	0.399	0.000
M15-M19 Arthrosis	0.601	0.399	0.000
M33.9 Dermatopolymyositis, unspecified	0.600	0.399	0.000
M33.0 Juvenile dermatomyositis	0.600	0.399	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.600	0.400	0.000
M19 Other arthrosis	0.598	0.402	0.000
M19.9 Arthrosis, unspecified	0.596	0.404	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.592	0.408	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.585	0.415	0.000
M24.64 Ankylosis of joint (Hand)	0.583	0.417	0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.581	0.419	0.000
M24.1 Other articular cartilage disorders	0.579	0.421	0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.578	0.422	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.573	0.427	0.000
M16 Coxarthrosis [arthrosis of hip]	0.572	0.428	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.571	0.429	0.000
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.571	0.429	0.000
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.571	0.429	0.000
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.571	0.429	0.000
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.571	0.429	0.000
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.571	0.429	0.000
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.571	0.429	0.000
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.571	0.429	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.567	0.433	0.000
M16.9 Coxarthrosis, unspecified	0.567	0.433	0.000
M24.57 Contracture of joint (Ankle and foot)	0.561	0.439	0.000
M15 Polyarthrosis	0.559	0.441	0.000
M23.07 Cystic meniscus-Capsular lig	0.555	0.445	0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.555	0.445	0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.555	0.445	0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.555	0.445	0.000
M23.00 Cystic meniscus (Multiple sites)	0.555	0.445	0.000
M19.97 Arthrosis, unspecified (Ankle and foot)	0.554	0.446	0.000
M24.51 Contracture of joint (Shoulder region)	0.553	0.446	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.546	0.454	0.000
M24.98 Joint derangement, unspecified (Other)	0.546	0.454	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.546	0.454	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.546	0.454	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.546	0.454	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.546	0.454	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.546	0.454	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.546	0.454	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.544	0.456	0.000
M35.8 Other specified systemic involvement of connective tissue	0.540	0.460	0.000
M35.7 Hypermobility syndrome	0.540	0.460	0.000
M24.59 Contracture of joint (Site unspecified)	0.538	0.462	0.000
M24.58 Contracture of joint (Other)	0.538	0.462	0.000
M24.53 Contracture of joint (Forearm)	0.538	0.462	0.000
M24.50 Contracture of joint (Multiple sites)	0.538	0.462	0.000
M30.0 Polyarteritis nodosa	0.538	0.462	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.537	0.463	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.537	0.463	0.000
M05-M14 Inflammatory polyarthropathies	0.533	0.467	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.532	0.468	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.530	0.470	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.529	0.471	0.000
M24.52 Contracture of joint (Upper arm)	0.527	0.472	0.000
M19.99 Arthrosis, unspecified (Site unspecified)	0.525	0.475	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.516	0.484	0.000
M36.3 Arthropathy in other blood disorders	0.516	0.484	0.000
M36.2 Haemophilic arthropathy	0.516	0.484	0.000
M36.1 Arthropathy in neoplastic disease	0.516	0.484	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.516	0.484	0.000
M60-M63 Disorders of muscles	0.515	0.485	0.000
M15.1 Heberden's nodes (with arthropathy)	0.511	0.489	0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.511	0.489	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.510	0.490	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.510	0.490	0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.510	0.490	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.504	0.495	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.504	0.495	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.504	0.495	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.504	0.495	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.504	0.495	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.504	0.495	0.000
M32.8 Other forms of systemic lupus erythematosus	0.504	0.496	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.502	0.498	0.000
M24.68 Ankylosis of joint (Other)	0.502	0.498	0.000
M24.63 Ankylosis of joint (Forearm)	0.502	0.498	0.000
M24.62 Ankylosis of joint (Upper arm)	0.502	0.498	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.502	0.498	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.502	0.498	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.502	0.498	0.000
M16.3 Other dysplastic coxarthrosis	0.496	0.504	0.000
M05 Seropositive rheumatoid arthritis	0.495	0.505	0.000
M19.8 Other specified arthrosis	0.495	0.505	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.494	0.506	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.494	0.506	0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.494	0.506	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.493	0.506	0.000
M30.2 Juvenile polyarteritis	0.493	0.506	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.491	0.509	0.000
M15.2 Bouchard's nodes (with arthropathy)	0.490	0.510	0.000
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.489	0.511	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.488	0.512	0.000
M31 Other necrotising vasculopathies	0.483	0.517	0.000
M16.5 Other posttraumatic coxarthrosis	0.479	0.521	0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.473	0.527	0.000
M23.17 Discoid meniscus (congenital)-Capsular lig	0.473	0.527	0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.473	0.527	0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.473	0.527	0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.473	0.527	0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.473	0.527	0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.473	0.527	0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.473	0.527	0.000
M62 Other disorders of muscle	0.471	0.529	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.470	0.530	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.470	0.530	0.000
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.467	0.533	0.000
M24.66 Ankylosis of joint (Lower leg)	0.462	0.538	0.000
M21 Other acquired deformities of limbs	0.462	0.538	0.000
M35.3 Polymyalgia rheumatica	0.460	0.540	0.000
M35.9 Systemic involvement of connective tissue, unspecified	0.460	0.540	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.460	0.540	0.000
M35.5 Multifocal fibrosclerosis	0.460	0.540	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.460	0.540	0.000
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.459	0.541	0.000
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.459	0.541	0.000
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.459	0.541	0.000
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.459	0.541	0.000
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.459	0.541	0.000
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.459	0.541	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.456	0.544	0.000
M24.0 Loose body in joint	0.454	0.545	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.451	0.549	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.451	0.549	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.451	0.549	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.451	0.549	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.451	0.549	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.451	0.549	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.451	0.549	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.451	0.549	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.451	0.549	0.000
M19.2 Other secondary arthrosis	0.451	0.549	0.000
M80-M85 Disorders of bone density and structure	0.448	0.552	0.000
M08 Juvenile arthritis	0.448	0.552	0.000
M15.9 Polyarthrosis, unspecified	0.447	0.553	0.000
M24.79 Protrusio acetabuli-Site unspec	0.446	0.554	0.000
M24.78 Protrusio acetabuli-Other	0.446	0.554	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.446	0.554	0.000
M24.76 Protrusio acetabuli-Lower leg	0.446	0.554	0.000
M24.74 Protrusio acetabuli-Hand	0.446	0.554	0.000
M24.73 Protrusio acetabuli-Forearm	0.446	0.554	0.000
M24.72 Protrusio acetabuli-Upper arm	0.446	0.554	0.000
M24.71 Protrusio acetabuli-Shldr region	0.446	0.554	0.000
M24.70 Protrusio acetabuli-Mult sites	0.446	0.554	0.000
M06 Other rheumatoid arthritis	0.438	0.562	0.000
M84 Disorders of continuity of bone	0.435	0.565	0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.432	0.567	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.429	0.571	0.000
M15.4 Erosive (osteo)arthrosis	0.428	0.572	0.000
M35.2 Behcet's disease	0.423	0.576	0.000
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.423	0.577	0.000
M05.2 Rheumatoid vasculitis	0.421	0.579	0.000
M13 Other arthritis	0.419	0.581	0.000
M11 Other crystal arthropathies	0.417	0.583	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.415	0.585	0.000
M24.18 Other articular cartilage disorders (Other)	0.415	0.585	0.000
M24.14 Other articular cartilage disorders (Hand)	0.415	0.585	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.415	0.585	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.415	0.585	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.414	0.586	0.000
M31.6 Other giant cell arteritis	0.412	0.588	0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.411	0.589	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.411	0.589	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.410	0.590	0.000
M24.54 Contracture of joint (Hand)	0.409	0.590	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.407	0.593	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.405	0.594	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.405	0.595	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.405	0.595	0.000
M06.4 Inflammatory polyarthropathy	0.403	0.597	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.400	0.600	0.000
M19.84 Other specified arthrosis (Hand)	0.399	0.601	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.397	0.603	0.000
M15.0 Primary generalised (osteo)arthrosis	0.395	0.604	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.394	0.606	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.390	0.610	0.000
M19.81 Other specified arthrosis (Shoulder region)	0.387	0.613	0.000
M08.0 Juvenile rheumatoid arthritis	0.387	0.613	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.386	0.614	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.386	0.614	0.000
M23.30 Other meniscus derangements (Multiple sites)	0.385	0.615	0.000
M19.0 Primary arthrosis of other joints	0.385	0.615	0.000
M24.24 Disorder of ligament (Hand)	0.384	0.615	0.001
M09 Juvenile arthritis in diseases classified elsewhere	0.382	0.618	0.000
M19.1 Posttraumatic arthrosis of other joints	0.380	0.620	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.379	0.621	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.378	0.621	0.000
M24.02 Loose body in joint (Upper arm)	0.376	0.624	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.374	0.626	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.372	0.628	0.000
M40-M43 Deforming dorsopathies	0.371	0.629	0.000
M31.1 Thrombotic microangiopathy	0.370	0.630	0.000
M63 Disorders of muscle in diseases classified elsewhere	0.369	0.631	0.000
M61 Calcification and ossification of muscle	0.369	0.631	0.000
M21.4 Flat foot [pes planus] (acquired)	0.368	0.632	0.000
M15.99 Polyosteoarthritis, unspecified	0.367	0.633	0.000
M13.9 Arthritis, unspecified	0.366	0.634	0.000
M21.9 Acquired deformity of limb, unspecified	0.364	0.635	0.000
M62.0 Diastasis of muscle	0.364	0.636	0.000
M13.96 Arthritis, unspecified (Lower leg)	0.362	0.638	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.362	0.638	0.000
M19.89 Other specified arthrosis (Site unspecified)	0.362	0.638	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.362	0.638	0.000
M05.1 Rheumatoid lung disease	0.360	0.640	0.000
M83 Adult osteomalacia	0.359	0.641	0.000
M19.21 Other secondary arthrosis (Shoulder region)	0.357	0.643	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.355	0.645	0.000
M05.0 Felty's syndrome	0.355	0.645	0.000
M19.88 Other specified arthrosis (Other)	0.355	0.645	0.000
M19.86 Other specified arthrosis (Lower leg)	0.355	0.645	0.000
M19.85 Other specified arthrosis (Pelvic region and thigh)	0.355	0.645	0.000
M19.83 Other specified arthrosis (Forearm)	0.355	0.645	0.000
M19.82 Other specified arthrosis (Upper arm)	0.355	0.645	0.000
M19.80 Other specified arthrosis (Multiple sites)	0.355	0.645	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.354	0.645	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.354	0.646	0.000
M62.9 Disorder of muscle, unspecified	0.354	0.646	0.000
M35.1 Other overlap syndromes	0.350	0.650	0.000
M19.87 Other specified arthrosis (Ankle and foot)	0.349	0.651	0.000
M19.94 Arthrosis, unspecified (Hand)	0.349	0.651	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.348	0.652	0.000
M00-M03 Infectious arthropathies	0.347	0.653	0.000
M31.2 Lethal midline granuloma	0.346	0.654	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.345	0.655	0.000
M14 Arthropathies in other diseases classified elsewhere	0.342	0.658	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.342	0.658	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.341	0.658	0.000
M19.23 Other secondary arthrosis (Forearm)	0.341	0.659	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.341	0.659	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.339	0.661	0.000
M06.0 Seronegative rheumatoid arthritis	0.339	0.661	0.000
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.338	0.662	0.001
M62.4 Contracture of muscle	0.338	0.662	0.000
M62.3 Immobility syndrome (paraplegic)	0.338	0.662	0.000
M62.2 Ischaemic infarction of muscle	0.338	0.662	0.000
M62.6 Muscle strain	0.337	0.663	0.000
M24.03 Loose body in joint (Forearm)	0.337	0.663	0.000
M06.1 Adult-onset Still's disease	0.336	0.664	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.335	0.665	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.334	0.665	0.000
M16.7 Other secondary coxarthrosis	0.334	0.666	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.334	0.666	0.000
M19.90 Arthrosis, unspecified (Multiple sites)	0.333	0.667	0.000
M60 Myositis	0.332	0.668	0.000
M84.2 Delayed union of fracture	0.332	0.668	0.000
M12 Other specific arthropathies	0.330	0.670	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.330	0.670	0.000
M06.3 Rheumatoid nodule	0.328	0.672	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.327	0.673	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.327	0.673	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.327	0.673	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.326	0.673	0.000
M31.8 Other specified necrotising vasculopathies	0.326	0.674	0.000
M31.7 Microscopic polyangiitis	0.326	0.674	0.000
M24.09 Loose body in joint (Site unspecified)	0.326	0.674	0.000
M24.08 Loose body in joint (Other)	0.326	0.674	0.000
M24.06 Loose body in joint-Lower leg	0.326	0.674	0.000
M24.00 Loose body in joint (Multiple sites)	0.326	0.674	0.000
M62.11 Other rupture of muscle (nontraumatic) (Shoulder region)	0.325	0.675	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.325	0.675	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.324	0.675	0.000
M19.29 Other secondary arthrosis (Site unspecified)	0.323	0.677	0.000
M19.28 Other secondary arthrosis (Other)	0.323	0.677	0.000
M19.26 Other secondary arthrosis of other joints-Lower leg	0.323	0.677	0.000
M19.25 Other secondary arthrosis (Pelvic region and thigh)	0.323	0.677	0.000
M19.24 Other secondary arthrosis (Hand)	0.323	0.677	0.000
M19.22 Other secondary arthrosis (Upper arm)	0.323	0.677	0.000
M19.20 Other secondary arthrosis (Multiple sites)	0.323	0.677	0.000
M11.8 Other specified crystal arthropathies	0.323	0.677	0.000
M08.00 Juvenile rheumatoid arthritis (Multiple sites)	0.322	0.678	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.322	0.678	0.000
M15.8 Other polyarthrosis	0.321	0.678	0.000
M08.9 Juvenile arthritis, unspecified	0.321	0.679	0.000
M08.8 Other juvenile arthritis	0.321	0.679	0.000
M08.4 Pauciarticular juvenile arthritis	0.321	0.679	0.000
M08.3 Juvenile polyarthritis (seronegative)	0.321	0.679	0.000
M08.2 Juvenile arthritis with systemic onset	0.321	0.679	0.000
M08.1 Juvenile ankylosing spondylitis	0.321	0.679	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.320	0.680	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.319	0.680	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.317	0.682	0.000
M84.3 Stress fracture, not elsewhere classified	0.317	0.683	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.316	0.684	0.000
M31.9 Necrotising vasculopathy, unspecified	0.315	0.685	0.000
M06.2 Rheumatoid bursitis	0.314	0.686	0.000
M13.0 Polyarthritis, unspecified	0.314	0.686	0.000
M18 Arthrosis of first carpometacarpal joint	0.314	0.686	0.000
M13.98 Arthritis, unspecified (Other)	0.314	0.686	0.000
M08.09 Juvenile rheumatoid arthritis (Site unspecified)	0.313	0.687	0.000
M84.0 Malunion of fracture	0.312	0.688	0.000
M84.9 Disorder of continuity of bone, unspecified	0.312	0.688	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.312	0.688	0.000
M21.1 Varus deformity, not elsewhere classified	0.311	0.689	0.000
M15.3 Secondary multiple arthrosis	0.310	0.690	0.000
M21.7 Unequal limb length (acquired)	0.309	0.690	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.307	0.693	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.307	0.693	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.307	0.693	0.000
M05.8 Other seropositive rheumatoid arthritis	0.306	0.693	0.000
M11.2 Other chondrocalcinosis	0.306	0.693	0.000
M24.04 Loose body in joint (Hand)	0.306	0.694	0.000
M11.9 Crystal arthropathy, unspecified	0.306	0.694	0.000
M13.92 Arthritis, unspecified (Upper arm)	0.306	0.694	0.000
M84.8 Other disorders of continuity of bone	0.305	0.694	0.000
M91-M94 Chondropathies	0.305	0.695	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.305	0.695	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.303	0.697	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.303	0.697	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.303	0.697	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.303	0.697	0.000
M65-M68 Disorders of synovium and tendon	0.303	0.697	0.000
M05.28 Rheumatoid vasculitis (Other)	0.302	0.698	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.302	0.698	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.302	0.698	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.302	0.698	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.302	0.698	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.302	0.698	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.302	0.698	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.302	0.698	0.000
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.301	0.698	0.000
M06.8 Other specified rheumatoid arthritis	0.301	0.699	0.000
M11.1 Familial chondrocalcinosis	0.299	0.701	0.000
M11.0 Hydroxyapatite deposition disease	0.299	0.701	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.298	0.702	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.298	0.702	0.000
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.297	0.702	0.000
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.297	0.703	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.297	0.703	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.297	0.703	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.297	0.703	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.297	0.703	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.297	0.703	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.297	0.703	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.297	0.703	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.296	0.704	0.000
M85 Other disorders of bone density and structure	0.295	0.705	0.000
M70-M79 Other soft tissue disorders	0.293	0.707	0.000
M83.1 Senile osteomalacia	0.293	0.707	0.000
M21.0 Valgus deformity, not elsewhere classified	0.292	0.708	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.289	0.711	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.289	0.711	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.289	0.711	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.289	0.711	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.289	0.711	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.289	0.711	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.289	0.711	0.000
M07 Psoriatic and enteropathic arthropathies	0.288	0.712	0.000
M62.08 Diastasis of muscle (Other)	0.288	0.712	0.000
M19.27 Other secondary arthrosis (Ankle and foot)	0.285	0.715	0.000
M13.91 Arthritis, unspecified (Shoulder region)	0.284	0.716	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.282	0.718	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.280	0.720	0.000
M13.1 Monoarthritis, not elsewhere classified	0.278	0.721	0.000
M62.8 Other specified disorders of muscle	0.278	0.722	0.000
M15.00 Primary generalized (osteo)arthrosis, Multiple sites	0.278	0.722	0.000
M08.08 Juvenile rheumatoid arthritis (Other)	0.277	0.723	0.000
M08.07 Juvenile rheumatoid arthritis (Ankle and foot)	0.277	0.723	0.000
M08.06 Juvenile rheumatoid arthritis (Lower leg)	0.277	0.723	0.000
M08.05 Juvenile rheumatoid arthritis (Pelvic region and thigh)	0.277	0.723	0.000
M08.04 Juvenile rheumatoid arthritis (Hand)	0.277	0.723	0.000
M08.03 Juvenile rheumatoid arthritis (Forearm)	0.277	0.723	0.000
M08.02 Juvenile rheumatoid arthritis (Upper arm)	0.277	0.723	0.000
M08.01 Juvenile rheumatoid arthritis (Shoulder region)	0.277	0.723	0.000
M62.19 Other rupture of muscle (nontraumatic) (Site unspecified)	0.277	0.723	0.000
M62.18 Other rupture of muscle (nontraumatic) (Other)	0.277	0.723	0.000
M62.17 Other rupture of muscle (nontraumatic) (Ankle and foot)	0.277	0.723	0.000
M62.16 Other rupture of muscle (nontraumatic) (Lower leg)	0.277	0.723	0.000
M62.15 Other rupture of muscle (nontraumatic) (Pelvic region and thigh)	0.277	0.723	0.000
M62.14 Other rupture of muscle (nontraumatic) (Hand)	0.277	0.723	0.000
M62.13 Other rupture of muscle (nontraumatic) (Forearm)	0.277	0.723	0.000
M62.12 Other rupture of muscle (nontraumatic) (Upper arm)	0.277	0.723	0.000
M62.10 Other rupture of muscle (nontraumatic) (Multiple sites)	0.277	0.723	0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.276	0.724	0.000
M19.06 Primary arthrosis of other joints-Lower leg	0.275	0.725	0.000
M76 Enthesopathies of lower limb, excluding foot	0.275	0.725	0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere	0.274	0.726	0.000
M09.2 Juvenile arthritis in ulcerative colitis	0.274	0.726	0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]	0.274	0.726	0.000
M09.0 Juvenile arthritis in psoriasis	0.274	0.726	0.000
M84.07 Malunion of fracture (Ankle and foot)	0.274	0.726	0.000
M82 Osteoporosis in diseases classified elsewhere	0.273	0.727	0.000
M19.19 Post-traumatic arthrosis of other joints (Site unspecified)	0.272	0.727	0.000
M19.18 Post-traumatic arthrosis of other joints (Other)	0.272	0.727	0.000
M19.16 Post-traumatic arthrosis of other joints-Lower leg	0.272	0.727	0.000
M19.15 Post-traumatic arthrosis of other joints (Pelvic region and thigh)	0.272	0.727	0.000
M19.10 Post-traumatic arthrosis of other joints (Multiple sites)	0.272	0.727	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.271	0.729	0.000
M62.99 Disorder of muscle, unspecified (Site unspecified)	0.270	0.730	0.000
M19.12 Post-traumatic arthrosis of other joints (Upper arm)	0.270	0.730	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.270	0.730	0.000
M14.8 Arthropathies in other specified diseases classified elsewhere	0.269	0.731	0.000
M13.93 Arthritis, unspecified (Forearm)	0.269	0.731	0.000
M31.0 Hypersensitivity angiitis	0.268	0.732	0.000
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.266	0.733	0.000
M42 Spinal osteochondrosis	0.266	0.734	0.000
M61.9 Calcification and ossification of muscle, unspecified	0.265	0.735	0.000
M61.5 Other ossification of muscle	0.265	0.735	0.000
M61.4 Other calcification of muscle	0.265	0.735	0.000
M61.3 Calcification and ossification of muscles associated with burns	0.265	0.735	0.000
M61.2 Paralytic calcification and ossification of muscle	0.265	0.735	0.000
M61.1 Myositis ossificans progressiva	0.265	0.735	0.000
M61.0 Myositis ossificans traumatica	0.265	0.735	0.000
M63.8 Other disorders of muscle in diseases classified elsewhere	0.265	0.735	0.000
M63.3 Myositis in sarcoidosis	0.265	0.735	0.000
M63.2 Myositis in other infectious diseases classified elsewhere	0.265	0.735	0.000
M63.1 Myositis in protozoal and parasitic infections classified elsewhere	0.265	0.735	0.000
M63.0 Myositis in bacterial diseases classified elsewhere	0.265	0.735	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations