TreeWAS – Variant ID: rs10864728

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M47.89 Other spondylosis (Site unspecified)	0.000	0.972	0.028
M81.99 Osteoporosis, unspecified (Site unspecified)	0.028	0.972	0.000
M47.8 Other spondylosis	0.000	0.973	0.027
M47.82 Other spondylosis (Cervical region)	0.000	0.974	0.026
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.976	0.024
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.977	0.023
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.979	0.021
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.981	0.019
E16.2 Hypoglycaemia, unspecified	0.000	0.981	0.019
M47.84 Other spondylosis (Thoracic region)	0.000	0.981	0.019
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.019	0.981	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.981	0.019
R23.3 Spontaneous ecchymoses	0.018	0.982	0.000
M81.9 Osteoporosis, unspecified	0.017	0.983	0.000
H53.2 Diplopia	0.016	0.984	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.015	0.985	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.014	0.985	0.000
R23.4 Changes in skin texture	0.014	0.986	0.000
R23 Other skin changes	0.014	0.986	0.000
M47.86 Other spondylosis (Lumbar region)	0.000	0.986	0.014
M81.94 Osteoporosis, unspecified (Hand)	0.014	0.986	0.000
E16 Other disorders of pancreatic internal secretion	0.000	0.986	0.014
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.986	0.013
E87.5 Hyperkalaemia	0.000	0.987	0.013
M81.93 Osteoporosis, unspecified (Forearm)	0.013	0.987	0.000
R61.9 Hyperhidrosis, unspecified	0.013	0.987	0.000
E88 Other metabolic disorders	0.013	0.987	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.013	0.987	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.012	0.987	0.000
R23.8 Other and unspecified skin changes	0.012	0.988	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.012	0.988	0.000
E16.1 Other hypoglycaemia	0.000	0.988	0.012
I69.3 Sequelae of cerebral infarction	0.000	0.988	0.012
I69 Sequelae of cerebrovascular disease	0.000	0.989	0.011
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.989	0.011
E88.1 Lipodystrophy, not elsewhere classified	0.011	0.989	0.000
E88.2 Lipomatosis, not elsewhere classified	0.011	0.989	0.000
E88.8 Other specified metabolic disorders	0.010	0.990	0.000
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.990	0.010
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.990	0.010
E16.4 Abnormal secretion of gastrin	0.000	0.990	0.010
E16.3 Increased secretion of glucagon	0.000	0.990	0.010
R23.2 Flushing	0.010	0.990	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.990	0.010
E88.3 Tumour lysis syndrome	0.010	0.990	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.991	0.009
I44.2 Atrioventricular block, complete	0.000	0.991	0.009
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.991	0.009
N20.1 Calculus of ureter	0.009	0.991	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.991	0.009
E88.9 Metabolic disorder, unspecified	0.009	0.991	0.000
M81.98 Osteoporosis, unspecified (Other)	0.009	0.991	0.000
R23.0 Cyanosis	0.008	0.991	0.000
N20.0 Calculus of kidney	0.008	0.992	0.000
N20 Calculus of kidney and ureter	0.008	0.992	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.008	0.992	0.000
Q61.2 Polycystic kidney, adult type	0.000	0.992	0.008
J04.0 Acute laryngitis	0.000	0.992	0.008
M81.90 Osteoporosis, unspecified (Multiple sites)	0.008	0.992	0.000
J04.1 Acute tracheitis	0.000	0.992	0.008
M47 Spondylosis	0.000	0.992	0.008
N20.2 Calculus of kidney with calculus of ureter	0.007	0.993	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.993	0.007
F31 Bipolar affective disorder	0.007	0.993	0.000
R23.1 Pallor	0.007	0.993	0.000
M81 Osteoporosis without pathological fracture	0.007	0.993	0.000
Q61 Cystic kidney disease	0.000	0.993	0.007
V18.0 Driver injured in nontraffic accident	0.000	0.993	0.007
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.007	0.993	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.993	0.007
J04 Acute laryngitis and tracheitis	0.000	0.993	0.007
H73.8 Other specified disorders of tympanic membrane	0.006	0.994	0.000
M47.1 Other spondylosis with myelopathy	0.000	0.994	0.006
Q61.9 Cystic kidney disease, unspecified	0.000	0.994	0.006
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.006	0.994	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.006	0.994	0.000
Q61.5 Medullary cystic kidney	0.000	0.994	0.006
M47.12 Other spondylosis with myelopathy (Cervical region)	0.000	0.994	0.006
R61 Hyperhidrosis	0.006	0.994	0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.994	0.006
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.006	0.994	0.000
M47.0 Anterior spinal and vertebral artery compression syndromes	0.000	0.994	0.006
F31.7 Bipolar affective disorder, currently in remission	0.006	0.994	0.000
M47.2 Other spondylosis with radiculopathy	0.000	0.994	0.006
F31.8 Other bipolar affective disorders	0.005	0.994	0.000
Q61.0 Congenital single renal cyst	0.000	0.994	0.005
F31.6 Bipolar affective disorder, current episode mixed	0.005	0.994	0.000
M81.8 Other osteoporosis	0.005	0.995	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.005	0.995	0.000
M81.6 Localised osteoporosis [Lequesne]	0.005	0.995	0.000
M81.5 Idiopathic osteoporosis	0.005	0.995	0.000
M81.1 Postoophorectomy osteoporosis	0.005	0.995	0.000
Q61.4 Renal dysplasia	0.000	0.995	0.005
Q61.8 Other cystic kidney diseases	0.000	0.995	0.005
Q61.1 Polycystic kidney, infantile type	0.000	0.995	0.005
N20.9 Urinary calculus, unspecified	0.005	0.995	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.005	0.995	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.000	0.995	0.005
J04.2 Acute laryngotracheitis	0.000	0.995	0.005
M81.4 Drug-induced osteoporosis	0.005	0.995	0.000
M81.0 Postmenopausal osteoporosis	0.005	0.995	0.000
M47.19 Other spondylosis with myelopathy (Site unspecified)	0.000	0.995	0.005
M47.18 Other spondylosis with myelopathy (Sacral and sacrococcygeal region)	0.000	0.995	0.005
M47.17 Other spondylosis with myelopathy (Lumbosacral region)	0.000	0.995	0.005
M47.15 Other spondylosis with myelopathy (Thoracolumbar region)	0.000	0.995	0.005
M47.14 Other spondylosis with myelopathy (Thoracic region)	0.000	0.995	0.005
M47.13 Other spondylosis with myelopathy (Cervicothoracic region)	0.000	0.995	0.005
M47.11 Other spondylosis with myelopathy (Occipito-atlanto-axial region)	0.000	0.995	0.005
M47.10 Other spondylosis with myelopathy (Multiple sites in spine)	0.000	0.995	0.005
C32.0 Glottis	0.000	0.995	0.005
M81.2 Osteoporosis of disuse	0.005	0.995	0.000
R61.0 Localised hyperhidrosis	0.005	0.995	0.000
H73 Other disorders of tympanic membrane	0.005	0.995	0.000
E15 Nondiabetic hypoglycaemic coma	0.000	0.996	0.004
M47.09 Anterior spinal and vertebral artery compression syndromes (Site unspecified)	0.000	0.996	0.004
M47.08 Anterior spinal and vertebral artery compression syndromes (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M47.07 Anterior spinal and vertebral artery compression syndromes (Lumbosacral region)	0.000	0.996	0.004
M47.06 Anterior spinal and vertebral artery compression syndromes (Lumbar region)	0.000	0.996	0.004
M47.05 Anterior spinal and vertebral artery compression syndromes (Thoracolumbar region)	0.000	0.996	0.004
M47.04 Anterior spinal and vertebral artery compression syndromes (Thoracic region)	0.000	0.996	0.004
M47.03 Anterior spinal and vertebral artery compression syndromes (Cervicothoracic region)	0.000	0.996	0.004
M47.02 Anterior spinal and vertebral artery compression syndromes (Cervical region)	0.000	0.996	0.004
M47.01 Anterior spinal and vertebral artery compression syndromes (Occipito-atlanto-axial region)	0.000	0.996	0.004
M47.00 Anterior spinal and vertebral artery compression syndromes (Multiple sites in spine)	0.000	0.996	0.004
M47.16 Other spondylosis with myelopathy (Lumbar region)	0.000	0.996	0.004
M81.80 Other osteoporosis (Multiple sites)	0.004	0.996	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.000	0.996	0.004
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.000	0.996	0.004
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.000	0.996	0.004
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.000	0.996	0.004
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.000	0.996	0.004
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.000	0.996	0.004
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.000	0.996	0.004
M81.49 Drug-induced osteoporosis (Site unspecified)	0.004	0.996	0.000
D75.1 Secondary polycythaemia	0.000	0.996	0.004
N39.8 Other specified disorders of urinary system	0.000	0.996	0.004
M81.89 Other osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.88 Other osteoporosis (Other)	0.004	0.996	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.86 Other osteoporosis (Lower leg)	0.004	0.996	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.84 Other osteoporosis (Hand)	0.004	0.996	0.000
M81.83 Other osteoporosis (Forearm)	0.004	0.996	0.000
M81.82 Other osteoporosis (Upper arm)	0.004	0.996	0.000
M81.81 Other osteoporosis (Shoulder region)	0.004	0.996	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.000	0.996	0.004
F31.9 Bipolar affective disorder, unspecified	0.004	0.996	0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.004	0.996	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.004	0.996	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.004	0.996	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.004	0.996	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.004	0.996	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.004	0.996	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.004	0.996	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.58 Idiopathic osteoporosis (Other)	0.004	0.996	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.004	0.996	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.004	0.996	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.004	0.996	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.004	0.996	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.004	0.996	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.004	0.996	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.004	0.996	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.004	0.996	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.004	0.996	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.004	0.996	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.004	0.996	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.004	0.996	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.004	0.996	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.004	0.996	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.004	0.996	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.004	0.996	0.000
R61.1 Generalised hyperhidrosis	0.004	0.996	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.004	0.996	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.004	0.996	0.000
G35 Multiple sclerosis	0.004	0.996	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.004	0.996	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.004	0.996	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.004	0.996	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.004	0.996	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.004	0.996	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.004	0.996	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.004	0.996	0.000
M81.48 Drug-induced osteoporosis (Other)	0.004	0.996	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.004	0.996	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.004	0.996	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.004	0.996	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.004	0.996	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.004	0.996	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.004	0.996	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.004	0.996	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.004	0.996	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.004	0.996	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.004	0.996	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.004	0.996	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.004	0.996	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.004	0.996	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.004	0.996	0.000
S52.50 Fracture of lower end of radius (closed)	0.000	0.996	0.004
M81.29 Osteoporosis of disuse (Site unspecified)	0.003	0.996	0.000
M81.28 Osteoporosis of disuse (Other)	0.003	0.996	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.003	0.996	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.003	0.996	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.003	0.996	0.000
M81.24 Osteoporosis of disuse (Hand)	0.003	0.996	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.003	0.996	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.003	0.996	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.003	0.996	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.996	0.000
R44.1 Visual hallucinations	0.000	0.996	0.004
O36.6 Maternal care for excessive foetal growth	0.004	0.996	0.000
N20-N23 Urolithiasis	0.004	0.996	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.003	0.997	0.000
H72.8 Other perforations of tympanic membrane	0.003	0.997	0.000
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.997	0.003
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
L92.3 Foreign body granuloma of skin and subcutaneous tissue	0.000	0.997	0.003
Z35.5 Supervision of elderly primigravida	0.000	0.997	0.003
V18 Pedal cyclist injured in noncollision transport accident	0.000	0.997	0.003
M81.20 Osteoporosis of disuse (Multiple sites)	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
M85 Other disorders of bone density and structure	0.003	0.997	0.000
H72 Perforation of tympanic membrane	0.003	0.997	0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.000	0.997	0.003
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.997	0.003
H74.8 Other specified disorders of middle ear and mastoid	0.003	0.997	0.000
M85.20 Hyperostosis of skull-Mult sites	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.003	0.997	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.000	0.997	0.003
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.003	0.997	0.000
H74.4 Polyp of middle ear	0.003	0.997	0.000
J45.0 Predominantly allergic asthma	0.000	0.997	0.003
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
M80 Osteoporosis with pathological fracture	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
N22 Calculus of urinary tract in diseases classified elsewhere	0.003	0.997	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.997	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.997	0.003
R44.3 Hallucinations, unspecified	0.000	0.997	0.003
V18.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
M85.22 Hyperostosis of skull-Upper arm	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
J15.1 Pneumonia due to Pseudomonas	0.003	0.997	0.000
H72.1 Attic perforation of tympanic membrane	0.003	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
N21.8 Other lower urinary tract calculus	0.003	0.997	0.000
N21 Calculus of lower urinary tract	0.003	0.997	0.000
S70.0 Contusion of hip	0.000	0.997	0.003
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
S52.51 Fracture of lower end of radius (open)	0.000	0.997	0.003
R20.2 Paraesthesia of skin	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.003	0.997	0.000
H71 Cholesteatoma of middle ear	0.003	0.997	0.000
C32.9 Larynx, unspecified	0.000	0.997	0.003
N23 Unspecified renal colic	0.003	0.997	0.000
S52.5 Fracture of lower end of radius	0.000	0.997	0.003
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.997	0.000
H65.2 Chronic serous otitis media	0.003	0.997	0.000
C32 Malignant neoplasm of larynx	0.000	0.997	0.003
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.997	0.000
M80.8 Other osteoporosis with pathological fracture	0.002	0.997	0.000
H70 Mastoiditis and related conditions	0.002	0.997	0.000
R44 Other symptoms and signs involving general sensations and perceptions	0.000	0.997	0.003
V18.9 Unspecified pedal cyclist injured in traffic accident	0.000	0.997	0.002
V18.4 Driver injured in traffic accident	0.000	0.997	0.002
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
V18.5 Passenger injured in traffic accident	0.000	0.997	0.002
M85.29 Hyperostosis of skull-Site unspec	0.002	0.998	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.998	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.998	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.998	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.998	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.998	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.998	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.998	0.000
H66 Suppurative and unspecified otitis media	0.002	0.998	0.000
M85.47 Solitary bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.46 Solitary bone cyst (Lower leg)	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
N94.3 Premenstrual tension syndrome	0.000	0.998	0.002
H68 Eustachian salpingitis and obstruction	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.002	0.998	0.000
M85.3 Osteitis condensans	0.002	0.998	0.000
M85.1 Skeletal fluorosis	0.002	0.998	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998	0.000
N21.1 Calculus in urethra	0.002	0.998	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
V18.3 Person injured while boarding or alighting	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.998	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.002	0.998	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.002	0.998	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.002	0.998	0.000
Z86.4 Personal history of psychoactive substance abuse	0.000	0.998	0.002
G36 Other acute disseminated demyelination	0.002	0.998	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.000	0.998	0.002
N22.8 Calculus of urinary tract in other diseases classified elsewhere	0.002	0.998	0.000
N22.0 Calculus of urinary tract in schistosomiasis [bilharziasis]	0.002	0.998	0.000
H65 Nonsuppurative otitis media	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
R44.8 Other and unspecified symptoms and signs involving general sensations and perceptions	0.000	0.998	0.002
M85.49 Solitary bone cyst (Site unspecified)	0.002	0.998	0.000
M85.48 Solitary bone cyst (Other)	0.002	0.998	0.000
M85.44 Solitary bone cyst (Hand)	0.002	0.998	0.000
M85.43 Solitary bone cyst (Forearm)	0.002	0.998	0.000
M85.42 Solitary bone cyst (Upper arm)	0.002	0.998	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.002	0.998	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.002	0.998	0.000
M83 Adult osteomalacia	0.002	0.998	0.000
H70.8 Other mastoiditis and related conditions	0.002	0.998	0.000
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
N21.9 Calculus of lower urinary tract, unspecified	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.002	0.998	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.998	0.002
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
H70.9 Mastoiditis, unspecified	0.002	0.998	0.000
H72.2 Other marginal perforations of tympanic membrane	0.002	0.998	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.002	0.998	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.002	0.998	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.002	0.998	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.998	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
L71.1 Rhinophyma	0.002	0.998	0.000
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
C32.8 Overlapping lesion of larynx	0.000	0.998	0.002
C32.3 Laryngeal cartilage	0.000	0.998	0.002
C32.2 Subglottis	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
H70.2 Petrositis	0.002	0.998	0.000
M79.28 Neuralgia and neuritis, unspecified (Other)	0.002	0.998	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.998	0.000
S70.1 Contusion of thigh	0.000	0.998	0.002
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.000	0.998	0.002
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.000	0.998	0.002
H27.0 Aphakia	0.002	0.998	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.998	0.000
H70.0 Acute mastoiditis	0.002	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
M85.19 Skeletal fluorosis (Site unspecified)	0.002	0.998	0.000
M85.18 Skeletal fluorosis (Other)	0.002	0.998	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.002	0.998	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.002	0.998	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.002	0.998	0.000
M85.14 Skeletal fluorosis (Hand)	0.002	0.998	0.000
M85.13 Skeletal fluorosis (Forearm)	0.002	0.998	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.002	0.998	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.002	0.998	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.002	0.998	0.000
M85.39 Osteitis condensans (Site unspecified)	0.002	0.998	0.000
M85.38 Osteitis condensans (Other)	0.002	0.998	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.002	0.998	0.000
M85.36 Osteitis condensans (Lower leg)	0.002	0.998	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.002	0.998	0.000
M85.34 Osteitis condensans (Hand)	0.002	0.998	0.000
M85.33 Osteitis condensans (Forearm)	0.002	0.998	0.000
M85.32 Osteitis condensans (Upper arm)	0.002	0.998	0.000
M85.31 Osteitis condensans (Shoulder region)	0.002	0.998	0.000
M85.30 Osteitis condensans (Multiple sites)	0.002	0.998	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.002	0.998	0.000
M85.58 Aneurysmal bone cyst (Other)	0.002	0.998	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.002	0.998	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.002	0.998	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.002	0.998	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.002	0.998	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.002	0.998	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.002	0.998	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.002	0.998	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.002	0.998	0.000
H68.0 Eustachian salpingitis	0.002	0.998	0.000
M85.0 Fibrous dysplasia (monostotic)	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.002	0.998	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.002	0.998	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.002	0.998	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.002	0.998	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.002	0.998	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.002	0.998	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.002	0.998	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.002	0.998	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E11.6 With other specified complications	0.000	0.998	0.002
M83.1 Senile osteomalacia	0.002	0.998	0.000
R20 Disturbances of skin sensation	0.000	0.998	0.002
A87.9 Viral meningitis, unspecified	0.002	0.998	0.000
H66.0 Acute suppurative otitis media	0.002	0.998	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
H65.0 Acute serous otitis media	0.002	0.998	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
R44.2 Other hallucinations	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.002	0.998	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.002	0.998	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.002	0.998	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.002	0.998	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.002	0.998	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.002	0.998	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.002	0.998	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.002	0.998	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.002	0.998	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.002	0.998	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.002	0.998	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Y45.0 Opioids and related analgesics	0.002	0.998	0.000
S70 Superficial injury of hip and thigh	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.002	0.998	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.998	0.000
M83.4 Aluminum bone disease	0.002	0.998	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.998	0.000
M83.0 Puerperal osteomalacia	0.002	0.998	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.998	0.000
G37.5 Concentric sclerosis [Balo]	0.002	0.998	0.000
G37.4 Subacute necrotising myelitis	0.002	0.998	0.000
G37.2 Central pontine myelinolysis	0.002	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.002	0.998	0.000
G37.0 Diffuse sclerosis	0.002	0.998	0.000
H65.1 Other acute nonsuppurative otitis media	0.002	0.998	0.000
R44.0 Auditory hallucinations	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.000	0.998	0.002
F30.0 Hypomania	0.002	0.998	0.000
Z13.1 Special screening examination for diabetes mellitus	0.002	0.998	0.000
H70.1 Chronic mastoiditis	0.002	0.998	0.000
M83.9 Adult osteomalacia, unspecified	0.002	0.998	0.000
M83.12 Senile osteomalacia (Upper arm)	0.002	0.998	0.000
S52.20 Fracture of shaft of ulna (closed)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations