TreeWAS – Variant ID: rs10933436

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T46 Poisoning by agents primarily affecting the cardiovascular system	0.188	0.812	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.185	0.815	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.174	0.826	0.000
T46.1 Calcium-channel blockers	0.172	0.828	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.171	0.829	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.161	0.839	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.161	0.839	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.157	0.843	0.000
T43.2 Other and unspecified antidepressants	0.153	0.847	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.151	0.849	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.151	0.849	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.144	0.856	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.140	0.860	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.135	0.865	0.000
T46.7 Peripheral vasodilators	0.135	0.865	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.135	0.865	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.135	0.865	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.133	0.867	0.000
T47.0 Histamine H(2)-receptor antagonists	0.131	0.869	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.131	0.869	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.131	0.869	0.000
T42.4 Benzodiazepines	0.129	0.871	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.128	0.872	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.127	0.873	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.127	0.873	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.127	0.873	0.000
T47.6 Antidiarrhoeal drugs	0.127	0.873	0.000
T38.0 Glucocorticoids and synthetic analogues	0.126	0.874	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.125	0.875	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.123	0.877	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.123	0.877	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.122	0.877	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.117	0.883	0.000
T38.1 Thyroid hormones and substitutes	0.116	0.883	0.000
T38.9 Other and unspecified hormone antagonists	0.116	0.884	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.116	0.884	0.000
T38.7 Androgens and anabolic congeners	0.116	0.884	0.000
T38.5 Other oestrogens and progestogens	0.116	0.884	0.000
T38.4 Oral contraceptives	0.116	0.884	0.000
T38.2 Antithyroid drugs	0.116	0.884	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.115	0.885	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.115	0.885	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.115	0.885	0.000
T47.2 Stimulant laxatives	0.115	0.885	0.000
T42.1 Iminostilbenes	0.114	0.886	0.000
T43.6 Psychostimulants with abuse potential	0.113	0.887	0.000
T43.9 Psychotropic drug, unspecified	0.113	0.887	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.112	0.887	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.112	0.887	0.000
T47.7 Emetics	0.112	0.887	0.000
T47.5 Digestants	0.112	0.887	0.000
T47.3 Saline and osmotic laxatives	0.112	0.887	0.000
T36 Poisoning by systemic antibiotics	0.112	0.887	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.111	0.889	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.109	0.891	0.000
T42.2 Succinimides and oxazolidinediones	0.109	0.891	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.106	0.894	0.000
T47.4 Other laxatives	0.106	0.894	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.104	0.896	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.102	0.898	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.102	0.898	0.000
T42.3 Barbiturates	0.102	0.898	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.101	0.899	0.000
T37.5 Antiviral drugs	0.101	0.899	0.000
T37.4 Anthelminthics	0.101	0.899	0.000
T37.3 Other antiprotozoal drugs	0.101	0.899	0.000
T37.1 Antimycobacterial drugs	0.101	0.899	0.000
T37.0 Sulphonamides	0.101	0.899	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.100	0.900	0.000
T45.2 Vitamins, not elsewhere classified	0.100	0.900	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.098	0.901	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.094	0.906	0.000
T48.5 Anti-common-cold drugs	0.094	0.906	0.000
T48.4 Expectorants	0.094	0.906	0.000
T48.3 Antitussives	0.094	0.906	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.094	0.906	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.094	0.906	0.000
T48.0 Oxytocic drugs	0.094	0.906	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.093	0.907	0.000
T45.0 Antiallergic and antiemetic drugs	0.092	0.908	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.092	0.908	0.000
T45.8 Other primarily systemic and haematological agents	0.092	0.908	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.092	0.908	0.000
T45.6 Fibrinolysis-affecting drugs	0.092	0.908	0.000
T45.4 Iron and its compounds	0.092	0.908	0.000
T45.3 Enzymes, not elsewhere classified	0.092	0.908	0.000
T49.9 Topical agent, unspecified	0.091	0.909	0.000
T49.8 Other topical agents	0.091	0.909	0.000
T49.7 Dental drugs, topically applied	0.091	0.909	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.091	0.909	0.000
T49.5 Ophthalmological drugs and preparations	0.091	0.909	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.091	0.909	0.000
T49.3 Emollients, demulcents and protectants	0.091	0.909	0.000
T49.2 Local astringents and local detergents	0.091	0.909	0.000
T49.1 Antipruritics	0.091	0.909	0.000
T45.5 Anticoagulants	0.091	0.909	0.000
T41.5 Therapeutic gases	0.090	0.910	0.000
T41.4 Anaesthetic, unspecified	0.090	0.910	0.000
T41.3 Local anaesthetics	0.090	0.910	0.000
T41.2 Other and unspecified general anaesthetics	0.090	0.910	0.000
T41.1 Intravenous anaesthetics	0.090	0.910	0.000
T41.0 Inhaled anaesthetics	0.090	0.910	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.088	0.912	0.000
T42.0 Hydantoin derivatives	0.088	0.912	0.000
T36.4 Tetracyclines	0.085	0.914	0.000
T36.8 Other systemic antibiotics	0.085	0.915	0.000
T50.1 Loop [high-ceiling] diuretics	0.083	0.917	0.000
T39.0 Salicylates	0.082	0.918	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.082	0.918	0.000
T50.4 Drugs affecting uric acid metabolism	0.081	0.919	0.000
T36.9 Systemic antibiotic, unspecified	0.081	0.919	0.000
T36.7 Antifungal antibiotics, systemically used	0.081	0.919	0.000
T36.6 Rifamycins	0.081	0.919	0.000
T36.5 Aminoglycosides	0.081	0.919	0.000
T36.2 Chloramphenicol group	0.081	0.919	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.081	0.919	0.000
T50.7 Analeptics and opioid receptor antagonists	0.076	0.924	0.000
T50.5 Appetite depressants	0.076	0.924	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.076	0.924	0.000
T50.0 Mineralocorticoids and their antagonists	0.076	0.924	0.000
T39.1 4-Aminophenol derivatives	0.076	0.924	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.075	0.925	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.075	0.925	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.074	0.925	0.000
T39.4 Antirheumatics, not elsewhere classified	0.073	0.927	0.000
T39.2 Pyrazolone derivatives	0.073	0.927	0.000
T36.3 Macrolides	0.072	0.927	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.928	0.072
T50.9 Other and unspecified drugs, medicaments and biological substances	0.072	0.928	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.072	0.928	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.071	0.929	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.071	0.929	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.071	0.929	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.071	0.929	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.071	0.929	0.000
T44.0 Anticholinesterase agents	0.071	0.929	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.070	0.930	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.068	0.931	0.000
S64 Injury of nerves at wrist and hand level	0.000	0.932	0.068
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.067	0.933	0.000
S64.3 Injury of digital nerve of thumb	0.000	0.934	0.066
T36.0 Penicillins	0.065	0.935	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.937	0.063
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.061	0.939	0.000
T40.6 Other and unspecified narcotics	0.055	0.945	0.000
T50.8 Diagnostic agents	0.053	0.947	0.000
T40.1 Heroin	0.053	0.947	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.948	0.052
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.052	0.948	0.000
T40.8 Lysergide [LSD]	0.052	0.948	0.000
T40.7 Cannabis (derivatives)	0.052	0.948	0.000
T40.3 Methadone	0.052	0.948	0.000
T40.0 Opium	0.052	0.948	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.948	0.052
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.951	0.049
S64.8 Injury of other nerves at wrist and hand level	0.000	0.951	0.049
T40.5 Cocaine	0.047	0.953	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.045	0.955	0.000
T40.4 Other synthetic narcotics	0.044	0.956	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.044	0.956	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.958	0.042
C45.0 Mesothelioma of pleura	0.037	0.963	0.000
C45 Mesothelioma	0.036	0.964	0.000
C45.9 Mesothelioma, unspecified	0.036	0.964	0.000
C45.7 Mesothelioma of other sites	0.033	0.967	0.000
C45.2 Mesothelioma of pericardium	0.026	0.974	0.000
C45.1 Mesothelioma of peritoneum	0.026	0.974	0.000
J35.0 Chronic tonsillitis	0.019	0.981	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.019	0.981	0.000
T40.2 Other opioids	0.018	0.982	0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.016	0.984	0.000
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.015	0.985	0.000
R02 Gangrene, not elsewhere classified	0.014	0.986	0.000
C46 Kaposi's sarcoma	0.014	0.986	0.000
C48.0 Retroperitoneum	0.014	0.986	0.000
T51.0 Ethanol	0.013	0.987	0.000
Q21.1 Atrial septal defect	0.000	0.987	0.013
C48.2 Peritoneum, unspecified	0.013	0.987	0.000
C47.1 Peripheral nerves of upper limb, including shoulder	0.012	0.987	0.000
C48.8 Overlapping lesion of retroperitoneum and peritoneum	0.011	0.988	0.000
C47.9 Peripheral nerves and autonomic nervous system, unspecified	0.011	0.989	0.000
C47.8 Overlapping lesion of peripheral nerves and autonomic nervous system	0.011	0.989	0.000
C47.6 Peripheral nerves of trunk, unspecified	0.011	0.989	0.000
C47.5 Peripheral nerves of pelvis	0.011	0.989	0.000
C47.4 Peripheral nerves of abdomen	0.011	0.989	0.000
C47.3 Peripheral nerves of thorax	0.011	0.989	0.000
C47.2 Peripheral nerves of lower limb, including hip	0.011	0.989	0.000
C47.0 Peripheral nerves of head, face and neck	0.011	0.989	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.011	0.989	0.000
C48.1 Specified parts of peritoneum	0.010	0.990	0.000
C46.9 Kaposi's sarcoma, unspecified	0.010	0.990	0.000
C46.8 Kaposi's sarcoma of multiple organs	0.010	0.990	0.000
C46.7 Kaposi's sarcoma of other sites	0.010	0.990	0.000
C46.3 Kaposi's sarcoma of lymph nodes	0.010	0.990	0.000
C46.2 Kaposi's sarcoma of palate	0.010	0.990	0.000
C46.1 Kaposi's sarcoma of soft tissue	0.010	0.990	0.000
C46.0 Kaposi's sarcoma of skin	0.010	0.990	0.000
Q21 Congenital malformations of cardiac septa	0.000	0.991	0.009
J35 Chronic diseases of tonsils and adenoids	0.009	0.991	0.000
C49.0 Connective and soft tissue of head, face and neck	0.009	0.991	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.009	0.991	0.000
C49.5 Connective and soft tissue of pelvis	0.009	0.991	0.000
C49.4 Connective and soft tissue of abdomen	0.009	0.991	0.000
Q21.0 Ventricular septal defect	0.000	0.991	0.009
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.008	0.992	0.000
C49.8 Overlapping lesion of connective and soft tissue	0.008	0.992	0.000
R68.8 Other specified general symptoms and signs	0.000	0.992	0.008
J35.2 Hypertrophy of adenoids	0.008	0.992	0.000
C49.9 Connective and soft tissue, unspecified	0.007	0.993	0.000
R52.9 Pain, unspecified	0.007	0.993	0.000
C49.3 Connective and soft tissue of thorax	0.007	0.993	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.993	0.007
S82.10 Fracture of upper end of tibia (closed)	0.000	0.993	0.007
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.007	0.993	0.000
J35.1 Hypertrophy of tonsils	0.007	0.993	0.000
M89.9 Disorder of bone, unspecified	0.007	0.993	0.000
Q21.8 Other congenital malformations of cardiac septa	0.000	0.993	0.007
Q21.4 Aortopulmonary septal defect	0.000	0.993	0.007
Q21.2 Atrioventricular septal defect	0.000	0.993	0.007
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.007	0.993	0.000
Q21.3 Tetralogy of Fallot	0.000	0.993	0.007
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.007	0.993	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.006	0.993	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.006	0.994	0.000
T51 Toxic effect of alcohol	0.006	0.994	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.006	0.994	0.000
M89.8 Other specified disorders of bone	0.006	0.994	0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.006	0.994	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.005	0.994	0.000
M89 Other disorders of bone	0.006	0.994	0.000
R68 Other general symptoms and signs	0.000	0.995	0.005
T58 Toxic effect of carbon monoxide	0.005	0.995	0.000
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.995	0.005
M89.86 Other specified disorders of bone (Lower leg)	0.005	0.995	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.005	0.995	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.005	0.995	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.005	0.995	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.005	0.995	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.005	0.995	0.000
M89.5 Osteolysis	0.005	0.995	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.995	0.005
M89.98 Disorder of bone, unspecified (Other)	0.005	0.995	0.000
T51.8 Other alcohols	0.005	0.995	0.000
T51.3 Fusel oil	0.005	0.995	0.000
T51.2 2-Propanol	0.005	0.995	0.000
T51.1 Methanol	0.005	0.995	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.005	0.995	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.004	0.995	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.004	0.996	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.004	0.996	0.000
C49.2 Connective and soft tissue of lower limb, including hip	0.004	0.996	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.004	0.996	0.000
N32.9 Bladder disorder, unspecified	0.004	0.996	0.000
M89.6 Osteopathy after poliomyelitis	0.004	0.996	0.000
M89.2 Other disorders of bone development and growth	0.004	0.996	0.000
M89.1 Epiphyseal arrest	0.004	0.996	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.004	0.996	0.000
R68.2 Dry mouth, unspecified	0.000	0.996	0.004
R68.1 Nonspecific symptoms peculiar to infancy	0.000	0.996	0.004
M89.89 Other specified disorders of bone (Site unspecified)	0.004	0.996	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.004	0.996	0.000
R68.3 Clubbing of fingers	0.000	0.996	0.004
M89.84 Other specified disorders of bone (Hand)	0.004	0.996	0.000
M89.83 Other specified disorders of bone (Forearm)	0.004	0.996	0.000
M89.56 Osteolysis (Lower leg)	0.004	0.996	0.000
M89.59 Osteolysis (Site unspecified)	0.004	0.996	0.000
M89.58 Osteolysis (Other)	0.004	0.996	0.000
M89.57 Osteolysis (Ankle and foot)	0.004	0.996	0.000
M89.54 Osteolysis (Hand)	0.004	0.996	0.000
M89.53 Osteolysis (Forearm)	0.004	0.996	0.000
M89.52 Osteolysis (Upper arm)	0.004	0.996	0.000
M89.51 Osteolysis (Shoulder region)	0.004	0.996	0.000
M89.50 Osteolysis (Multiple sites)	0.004	0.996	0.000
W19.2 School, other institution and public administrative area	0.000	0.996	0.004
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.996	0.004
M89.0 Algoneurodystrophy	0.004	0.996	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.003	0.996	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.003	0.996	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.003	0.996	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.003	0.996	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.003	0.996	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.003	0.996	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.003	0.996	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.003	0.996	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.003	0.996	0.000
T65 Toxic effect of other and unspecified substances	0.004	0.996	0.000
M89.88 Other specified disorders of bone (Other)	0.003	0.996	0.000
T54 Toxic effect of corrosive substances	0.003	0.997	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.003	0.997	0.000
M89.18 Epiphyseal arrest (Other)	0.003	0.997	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.003	0.997	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.003	0.997	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.003	0.997	0.000
M89.14 Epiphyseal arrest (Hand)	0.003	0.997	0.000
M89.13 Epiphyseal arrest (Forearm)	0.003	0.997	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.003	0.997	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.003	0.997	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.003	0.997	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.003	0.997	0.000
M89.28 Other disorders of bone development and growth (Other)	0.003	0.997	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.003	0.997	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.003	0.997	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.003	0.997	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.003	0.997	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.003	0.997	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.003	0.997	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.003	0.997	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.003	0.997	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.003	0.997	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.003	0.997	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.003	0.997	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.003	0.997	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.003	0.997	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.003	0.997	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.003	0.997	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.003	0.997	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.003	0.997	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.003	0.997	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.003	0.997	0.000
T60 Toxic effect of pesticides	0.003	0.997	0.000
T57 Toxic effect of other inorganic substances	0.003	0.997	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.003	0.997	0.000
T52 Toxic effect of organic solvents	0.003	0.997	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.003	0.997	0.000
T55 Toxic effect of soaps and detergents	0.003	0.997	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.000	0.997	0.003
M89.01 Algoneurodystrophy (Shoulder region)	0.003	0.997	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
T65.9 Toxic effect of unspecified substance	0.003	0.997	0.000
Z88.3 Personal history of allergy to other anti-infective agents	0.000	0.997	0.003
T21.3 Burn of third degree of trunk	0.000	0.997	0.003
M89.3 Hypertrophy of bone	0.003	0.997	0.000
T21 Burn and corrosion of trunk	0.000	0.997	0.003
Q43.8 Other specified congenital malformations of intestine	0.003	0.997	0.000
B35.3 Tinea pedis	0.003	0.997	0.000
M20.4 Other hammer toe(s) (acquired)	0.003	0.997	0.000
T20.0 Burn of unspecified degree of head and neck	0.000	0.997	0.003
T62 Toxic effect of other noxious substances eaten as food	0.003	0.997	0.000
I31.3 Pericardial effusion (noninflammatory)	0.003	0.997	0.000
M89.08 Algoneurodystrophy (Other)	0.003	0.997	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.003	0.997	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.003	0.997	0.000
F60.9 Personality disorder, unspecified	0.003	0.997	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.000	0.997	0.003
M89.00 Algoneurodystrophy (Multiple sites)	0.003	0.997	0.000
T65.8 Toxic effect of other specified substances	0.003	0.997	0.000
T65.6 Paints and dyes, not elsewhere classified	0.003	0.997	0.000
T65.5 Nitroglycerin and other nitric acids and esters	0.003	0.997	0.000
T65.4 Carbon disulphide	0.003	0.997	0.000
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.003	0.997	0.000
T65.2 Tobacco and nicotine	0.003	0.997	0.000
T65.1 Strychnine and its salts	0.003	0.997	0.000
T65.0 Cyanides	0.003	0.997	0.000
T56 Toxic effect of metals	0.003	0.997	0.000
M89.03 Algoneurodystrophy (Forearm)	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.000	0.997	0.003
T59 Toxic effect of other gases, fumes and vapours	0.003	0.997	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.997	0.003
T54.9 Corrosive substance, unspecified	0.003	0.997	0.000
Q43 Other congenital malformations of intestine	0.003	0.997	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.997	0.003
T21.2 Burn of second degree of trunk	0.000	0.997	0.003
M89.07 Algoneurodystrophy (Ankle and foot)	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.003	0.997	0.000
T54.3 Corrosive alkalis and alklali-like substances	0.002	0.997	0.000
T54.2 Corrosive acids and acid-like substances	0.002	0.997	0.000
T54.1 Other corrosive organic compounds	0.002	0.997	0.000
T54.0 Phenol and phenol homologues	0.002	0.997	0.000
K31.9 Disease of stomach and duodenum, unspecified	0.003	0.997	0.000
R94.3 Abnormal results of cardiovascular function studies	0.000	0.997	0.003
T52.9 Organic solvent, unspecified	0.002	0.997	0.000
T52.8 Other organic solvents	0.002	0.997	0.000
T52.4 Ketones	0.002	0.997	0.000
T52.3 Glycols	0.002	0.997	0.000
T52.2 Homologues of benzene	0.002	0.997	0.000
T52.1 Benzene	0.002	0.997	0.000
T52.0 Petroleum products	0.002	0.997	0.000
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.002	0.997	0.000
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.002	0.997	0.000
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.002	0.997	0.000
T53.5 Chlorofluorocarbons	0.002	0.997	0.000
T53.4 Dichloromethane	0.002	0.997	0.000
T53.3 Tetrachloroethylene	0.002	0.997	0.000
T53.2 Trichloroethylene	0.002	0.997	0.000
T53.1 Chloroform	0.002	0.997	0.000
T53.0 Carbon tetrachloride	0.002	0.997	0.000
T57.9 Inorganic substance, unspecified	0.002	0.997	0.000
T57.8 Other specified inorganic substances	0.002	0.997	0.000
T57.3 Hydrogen cyanide	0.002	0.997	0.000
T57.2 Manganese and its compounds	0.002	0.997	0.000
T57.1 Phosphorus and its compounds	0.002	0.997	0.000
T57.0 Arsenic and its compounds	0.002	0.997	0.000
T60.9 Pesticide, unspecified	0.002	0.997	0.000
T60.8 Other pesticides	0.002	0.997	0.000
T60.4 Rodenticides	0.002	0.997	0.000
T60.3 Herbicides and fungicides	0.002	0.997	0.000
T60.2 Other insecticides	0.002	0.997	0.000
T60.1 Halogenated insecticides	0.002	0.997	0.000
T60.0 Organophosphate and carbamate insecticides	0.002	0.997	0.000
T61.9 Toxic effect of unspecified seafood	0.002	0.997	0.000
T61.8 Toxic effect of other seafoods	0.002	0.997	0.000
T61.2 Other fish and shellfish poisoning	0.002	0.997	0.000
T61.1 Scombroid fish poisoning	0.002	0.997	0.000
T61.0 Ciguatera fish poisoning	0.002	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.000	0.997	0.003
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.997	0.003
T63 Toxic effect of contact with venomous animals	0.002	0.997	0.000
Z96.7 Presence of other bone and tendon implants	0.000	0.997	0.003
T21.0 Burn of unspecified degree of trunk	0.000	0.997	0.002
T25 Burn and corrosion of ankle and foot	0.000	0.997	0.003
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.997	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.997	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.997	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.997	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.997	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.997	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.997	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.997	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.997	0.000
S82.1 Fracture of upper end of tibia	0.000	0.997	0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q43.3 Congenital malformations of intestinal fixation	0.002	0.997	0.000
Q44.6 Cystic disease of liver	0.003	0.997	0.000
T21.7 Corrosion of third degree of trunk	0.000	0.997	0.002
T21.6 Corrosion of second degree of trunk	0.000	0.997	0.002
T21.5 Corrosion of first degree of trunk	0.000	0.997	0.002
T21.4 Corrosion of unspecified degree of trunk	0.000	0.997	0.002
T21.1 Burn of first degree of trunk	0.000	0.997	0.002
Q43.1 Hirschsprung's disease	0.002	0.997	0.000
T20.2 Burn of second degree of head and neck	0.000	0.998	0.002
T23.1 Burn of first degree of wrist and hand	0.000	0.998	0.002
T62.8 Other specified noxious substances eaten as food	0.002	0.998	0.000
T62.2 Other ingested (parts of) plant(s)	0.002	0.998	0.000
T62.1 Ingested berries	0.002	0.998	0.000
T62.0 Ingested mushrooms	0.002	0.998	0.000
F60.8 Other specific personality disorders	0.002	0.998	0.000
M79.60 Pain in limb (Multiple sites)	0.000	0.998	0.002
C85.1 B-cell lymphoma, unspecified	0.000	0.998	0.002
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T20.7 Corrosion of third degree of head and neck	0.000	0.998	0.002
T20.6 Corrosion of second degree of head and neck	0.000	0.998	0.002
T20.5 Corrosion of first degree of head and neck	0.000	0.998	0.002
T20.4 Corrosion of unspecified degree of head and neck	0.000	0.998	0.002
T20.3 Burn of third degree of head and neck	0.000	0.998	0.002
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
T56.9 Metal, unspecified	0.002	0.998	0.000
T56.7 Beryllium and its compounds	0.002	0.998	0.000
T56.6 Tin and its compounds	0.002	0.998	0.000
T56.5 Zinc and its compounds	0.002	0.998	0.000
T56.4 Copper and its compounds	0.002	0.998	0.000
T56.3 Cadmium and its compounds	0.002	0.998	0.000
T56.2 Chromium and its compounds	0.002	0.998	0.000
T56.1 Mercury and its compounds	0.002	0.998	0.000
T56.0 Lead and its compounds	0.002	0.998	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
Q38-Q45 Other congenital malformations of the digestive system	0.002	0.998	0.000
T59.7 Carbon dioxide	0.002	0.998	0.000
T59.6 Hydrogen sulphide	0.002	0.998	0.000
T59.5 Fluorine gas and hydrogen fluoride	0.002	0.998	0.000
T59.4 Chlorine gas	0.002	0.998	0.000
T59.3 Lachrymogenic gas	0.002	0.998	0.000
T59.2 Formaldehyde	0.002	0.998	0.000
T59.1 Sulphur dioxide	0.002	0.998	0.000
T59.0 Nitrogen oxides	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
Q43.7 Persistent cloaca	0.002	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.002	0.998	0.000
Q43.5 Ectopic anus	0.002	0.998	0.000
Q43.4 Duplication of intestine	0.002	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.002	0.998	0.000
T23.7 Corrosion of third degree of wrist and hand	0.000	0.998	0.002
T23.6 Corrosion of second degree of wrist and hand	0.000	0.998	0.002
T23.5 Corrosion of first degree of wrist and hand	0.000	0.998	0.002
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.998	0.002
T20.1 Burn of first degree of head and neck	0.000	0.998	0.002
T59.9 Gases, fumes and vapours, unspecified	0.002	0.998	0.000
F60 Specific personality disorders	0.002	0.998	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T51.9 Alcohol, unspecified	0.002	0.998	0.000
T25.3 Burn of third degree of ankle and foot	0.000	0.998	0.002
T25.2 Burn of second degree of ankle and foot	0.000	0.998	0.002
F60.3 Emotionally unstable personality disorder	0.002	0.998	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.998	0.002
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.000	0.998	0.002
T25.0 Burn of unspecified degree of ankle and foot	0.000	0.998	0.002
T63.9 Toxic effect of contact with unspecified venomous animal	0.002	0.998	0.000
T63.8 Toxic effect of contact with other venomous animals	0.002	0.998	0.000
T63.6 Toxic effect of contact with other marine animals	0.002	0.998	0.000
T63.5 Toxic effect of contact with fish	0.002	0.998	0.000
T63.3 Venom of spider	0.002	0.998	0.000
T63.2 Venom of scorpion	0.002	0.998	0.000
T63.1 Venom of other reptiles	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations