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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs10956252
log Bayes Factor = <0.0001
Chromosome 8   position 126,536,137  (GRCh37) Explore rs10956252 on Ensembl!
Variant rs10956252 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
C78.2 Secondary malignant neoplasm of pleura
0.044 0.956 0.000
M54.57 Low back pain (Lumbosacral region)
0.033 0.967 0.000
D35.1 Parathyroid gland
0.000 0.983 0.017
M54.5 Low back pain
0.016 0.984 0.000
M50.2 Other cervical disk displacement
0.015 0.985 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.014 0.986 0.000
M50 Cervical disk disorders
0.014 0.986 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.014 0.986 0.000
M65.34 Trigger finger-Hand
0.000 0.986 0.014
Z93.2 Ileostomy status
0.014 0.986 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.013 0.987 0.000
M50.1 Cervical disk disorder with radiculopathy
0.013 0.987 0.000
M54.50 Low back pain (Multiple sites in spine)
0.013 0.987 0.000
M54 Dorsalgia
0.012 0.988 0.000
M53 Other dorsopathies, not elsewhere classified
0.012 0.988 0.000
M50-M54 Other dorsopathies
0.012 0.988 0.000
M50.0 Cervical disk disorder with myelopathy
0.012 0.988 0.000
M54.52 Low back pain-Cervical
0.012 0.988 0.000
M54.53 Low back pain-Cervicothoracic
0.011 0.988 0.000
M54.51 Low back pain-Occipit-atl-axl
0.011 0.988 0.000
M54.55 Low back pain (Thoracolumbar region)
0.011 0.989 0.000
M54.3 Sciatica
0.011 0.989 0.000
M54.54 Low back pain-Thoracic
0.011 0.989 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.989 0.011
M54.37 Sciatica (Lumbosacral region)
0.011 0.989 0.000
M50.8 Other cervical disk disorders
0.011 0.989 0.000
E27.1 Primary adrenocortical insufficiency
0.000 0.989 0.011
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.010 0.990 0.000
D35.2 Pituitary gland
0.000 0.990 0.010
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.010 0.990 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.010 0.990 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.010 0.990 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.010 0.990 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.010 0.990 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.010 0.990 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.010 0.990 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.010 0.990 0.000
M54.39 Sciatica (Site unspecified)
0.010 0.990 0.000
E27 Other disorders of adrenal gland
0.000 0.990 0.010
D35 Benign neoplasm of other and unspecified endocrine glands
0.000 0.990 0.010
M53.2 Spinal instabilities
0.009 0.991 0.000
E21.0 Primary hyperparathyroidism
0.000 0.991 0.009
M53.9 Dorsopathy, unspecified
0.009 0.991 0.000
M54.0 Panniculitis affecting regions of neck and back
0.009 0.991 0.000
M54.6 Pain in thoracic spine
0.009 0.991 0.000
M53.1 Cervicobrachial syndrome
0.009 0.991 0.000
M53.0 Cervicocranial syndrome
0.009 0.991 0.000
M54.4 Lumbago with sciatica
0.009 0.991 0.000
M54.30 Sciatica (Multiple sites in spine)
0.009 0.991 0.000
M54.9 Dorsalgia, unspecified
0.009 0.991 0.000
M50.9 Cervical disk disorder, unspecified
0.009 0.991 0.000
T40.2 Other opioids
0.009 0.991 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.008 0.991 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.008 0.992 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.008 0.992 0.000
M54.35 Sciatica (Thoracolumbar region)
0.008 0.992 0.000
M54.34 Sciatica-Thoracic
0.008 0.992 0.000
M54.33 Sciatica-Cervicothoracic
0.008 0.992 0.000
M54.32 Sciatica-Cervical
0.008 0.992 0.000
M54.31 Sciatica-Occipit-atl-axl
0.008 0.992 0.000
M65.3 Trigger finger
0.000 0.992 0.008
M53.8 Other specified dorsopathies
0.007 0.992 0.000
M53.26 Spinal instabilities (Lumbar region)
0.007 0.992 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.000 0.992 0.008
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.992 0.008
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.007 0.992 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.007 0.992 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.007 0.992 0.000
M54.1 Radiculopathy
0.007 0.993 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.993 0.007
E27.5 Adrenomedullary hyperfunction
0.000 0.993 0.007
E27.0 Other adrenocortical overactivity
0.000 0.993 0.007
M53.96 Dorsopathy, unspecified (Lumbar region)
0.007 0.993 0.000
D35.9 Endocrine gland, unspecified
0.000 0.993 0.007
D35.8 Pluriglandular involvement
0.000 0.993 0.007
D35.7 Other specified endocrine glands
0.000 0.993 0.007
D35.6 Aortic body and other paraganglia
0.000 0.993 0.007
D35.5 Carotid body
0.000 0.993 0.007
D35.4 Pineal gland
0.000 0.993 0.007
D35.3 Craniopharyngeal duct
0.000 0.993 0.007
D86.8 Sarcoidosis of other and combined sites
0.007 0.993 0.000
N64.1 Fat necrosis of breast
0.007 0.993 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.993 0.007
D86 Sarcoidosis
0.007 0.993 0.000
M53.29 Spinal instabilities (Site unspecified)
0.007 0.993 0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M53.25 Spinal instabilities (Thoracolumbar region)
0.007 0.993 0.000
M53.24 Spinal instabilities (Thoracic region)
0.007 0.993 0.000
M53.23 Spinal instabilities (Cervicothoracic region)
0.007 0.993 0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.007 0.993 0.000
M53.20 Spinal instabilities (Multiple sites in spine)
0.007 0.993 0.000
D86.0 Sarcoidosis of lung
0.007 0.993 0.000
M53.22 Spinal instabilities (Cervical region)
0.007 0.993 0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.007 0.993 0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.007 0.993 0.000
M53.94 Dorsopathy, unspecified (Thoracic region)
0.007 0.993 0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.007 0.993 0.000
M53.92 Dorsopathy, unspecified (Cervical region)
0.007 0.993 0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.007 0.993 0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.007 0.993 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.007 0.993 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.007 0.993 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.007 0.993 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.007 0.993 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.007 0.993 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.007 0.993 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.007 0.993 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.007 0.993 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.007 0.993 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.007 0.993 0.000
M54.69 Pain in thoracic spine-Site unspe
0.007 0.993 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.007 0.993 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.007 0.993 0.000
M54.66 Pain in thoracic spine-Lumbar
0.007 0.993 0.000
M54.62 Pain in thoracic spine-Cervical
0.007 0.993 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.007 0.993 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.007 0.993 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.007 0.993 0.000
M53.09 Cervicocranial syndrome-Site unspe
0.007 0.993 0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.007 0.993 0.000
M53.07 Cervicocranial syndrome-Lumbosacral
0.007 0.993 0.000
M53.06 Cervicocranial syndrome-Lumbar
0.007 0.993 0.000
M53.05 Cervicocranial syndrome-Thoracolumbar
0.007 0.993 0.000
M53.04 Cervicocranial syndrome-Thoracic
0.007 0.993 0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.007 0.993 0.000
M53.02 Cervicocranial syndrome (Cervical region)
0.007 0.993 0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.007 0.993 0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.007 0.993 0.000
M53.19 Cervicobrachial syndrome-Site unspe
0.007 0.993 0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.007 0.993 0.000
M53.17 Cervicobrachial syndrome-Lumbosacral
0.007 0.993 0.000
M53.16 Cervicobrachial syndrome-Lumbar
0.007 0.993 0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.007 0.993 0.000
M53.14 Cervicobrachial syndrome-Thoracic
0.007 0.993 0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.007 0.993 0.000
M53.12 Cervicobrachial syndrome (Cervical region)
0.007 0.993 0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.007 0.993 0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.007 0.993 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.007 0.993 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.007 0.993 0.000
M54.44 Lumbago with sciatica-Thoracic
0.007 0.993 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.007 0.993 0.000
M54.42 Lumbago with sciatica-Cervical
0.007 0.993 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.007 0.993 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.007 0.993 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.007 0.993 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.007 0.993 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.000 0.993 0.007
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.006 0.993 0.000
M53.99 Dorsopathy, unspecified (Site unspecified)
0.006 0.994 0.000
D86.9 Sarcoidosis, unspecified
0.006 0.994 0.000
M53.27 Spinal instabilities (Lumbosacral region)
0.006 0.994 0.000
M65.39 Trigger finger-Site unspec
0.000 0.994 0.006
M96.8 Other postprocedural musculoskeletal disorders
0.000 0.994 0.006
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.000 0.994 0.006
E27.2 Addisonian crisis
0.000 0.994 0.006
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.006 0.994 0.000
E22 Hyperfunction of pituitary gland
0.000 0.994 0.006
E31 Polyglandular dysfunction
0.000 0.994 0.006
E27.9 Disorder of adrenal gland, unspecified
0.000 0.994 0.006
M65.38 Trigger finger-Other
0.000 0.994 0.006
M65.37 Trigger finger-Ankle/foot
0.000 0.994 0.006
M65.36 Trigger finger-Lower leg
0.000 0.994 0.006
M65.35 Trigger finger-Pelvic/thigh
0.000 0.994 0.006
M65.33 Trigger finger-Forearm
0.000 0.994 0.006
M65.32 Trigger finger-Upper arm
0.000 0.994 0.006
M65.31 Trigger finger-Shldr region
0.000 0.994 0.006
M65.30 Trigger finger-Mult sites
0.000 0.994 0.006
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.994 0.006
M53.89 Other specified dorsopathies (Site unspecified)
0.006 0.994 0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M53.87 Other specified dorsopathies (Lumbosacral region)
0.006 0.994 0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.006 0.994 0.000
M53.84 Other specified dorsopathies (Thoracic region)
0.006 0.994 0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.006 0.994 0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.006 0.994 0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.006 0.994 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.006 0.994 0.000
M50.3 Other cervical disk degeneration
0.006 0.994 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.006 0.994 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.994 0.006
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.006 0.994 0.000
E29 Testicular dysfunction
0.000 0.994 0.006
M54.14 Radiculopathy (Thoracic region)
0.005 0.994 0.000
M54.2 Cervicalgia
0.006 0.994 0.000
T43.2 Other and unspecified antidepressants
0.006 0.994 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.005 0.994 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.005 0.994 0.000
E26 Hyperaldosteronism
0.000 0.995 0.005
I61.4 Intracerebral haemorrhage in cerebellum
0.005 0.995 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.995 0.005
E32 Diseases of thymus
0.000 0.995 0.005
E30 Disorders of puberty, not elsewhere classified
0.000 0.995 0.005
M54.13 Radiculopathy (Cervicothoracic region)
0.005 0.995 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.005 0.995 0.000
D86.1 Sarcoidosis of lymph nodes
0.005 0.995 0.000
E25 Adrenogenital disorders
0.000 0.995 0.005
D33.2 Brain, unspecified
0.005 0.995 0.000
M54.19 Radiculopathy (Site unspecified)
0.005 0.995 0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified
0.000 0.995 0.005
E20 Hypoparathyroidism
0.000 0.995 0.005
M53.82 Other specified dorsopathies (Cervical region)
0.005 0.995 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.995 0.005
M53.86 Other specified dorsopathies (Lumbar region)
0.005 0.995 0.000
M54.12 Radiculopathy (Cervical region)
0.005 0.995 0.000
D86.3 Sarcoidosis of skin
0.005 0.995 0.000
E34 Other endocrine disorders
0.000 0.995 0.005
E28 Ovarian dysfunction
0.000 0.995 0.005
L40.9 Psoriasis, unspecified
0.005 0.995 0.000
M54.8 Other dorsalgia
0.005 0.995 0.000
E24 Cushing's syndrome
0.000 0.995 0.005
M54.17 Radiculopathy (Lumbosacral region)
0.005 0.995 0.000
E21.2 Other hyperparathyroidism
0.000 0.995 0.005
E31.0 Autoimmune polyglandular failure
0.000 0.995 0.005
E27.8 Other specified disorders of adrenal gland
0.000 0.995 0.005
D33.0 Brain, supratentorial
0.005 0.995 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.005 0.995 0.000
E21.4 Other specified disorders of parathyroid gland
0.000 0.995 0.005
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate
0.000 0.995 0.005
M96.4 Postsurgical lordosis
0.000 0.995 0.005
M96.3 Postlaminectomy kyphosis
0.000 0.995 0.005
M96.2 Postradiation kyphosis
0.000 0.995 0.005
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.995 0.005
M54.47 Lumbago with sciatica (Lumbosacral region)
0.004 0.995 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.995 0.004
D33 Benign neoplasm of brain and other parts of central nervous system
0.005 0.995 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.995 0.004
K52.0 Gastro-enteritis and colitis due to radiation
0.005 0.995 0.000
T40.3 Methadone
0.004 0.995 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.004 0.995 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.005 0.995 0.000
E31.9 Polyglandular dysfunction, unspecified
0.000 0.995 0.004
E31.8 Other polyglandular dysfunction
0.000 0.995 0.004
E31.1 Polyglandular hyperfunction
0.000 0.995 0.004
E29.1 Testicular hypofunction
0.000 0.995 0.004
E23.6 Other disorders of pituitary gland
0.000 0.996 0.004
E24.2 Drug-induced Cushing's syndrome
0.000 0.996 0.004
E34.8 Other specified endocrine disorders
0.000 0.996 0.004
E29.8 Other testicular dysfunction
0.000 0.996 0.004
E29.0 Testicular hyperfunction
0.000 0.996 0.004
T39.0 Salicylates
0.004 0.996 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.996 0.004
M54.27 Cervicalgia-Lumbosacral
0.004 0.996 0.000
M54.26 Cervicalgia-Lumbar
0.004 0.996 0.000
M54.25 Cervicalgia-Thoracolumbar
0.004 0.996 0.000
M54.24 Cervicalgia-Thoracic
0.004 0.996 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.004 0.996 0.000
M54.20 Cervicalgia-Mult site
0.004 0.996 0.000
E20.9 Hypoparathyroidism, unspecified
0.000 0.996 0.004
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.996 0.004
E29.9 Testicular dysfunction, unspecified
0.000 0.996 0.004
E26.8 Other hyperaldosteronism
0.000 0.996 0.004
E26.1 Secondary hyperaldosteronism
0.000 0.996 0.004
E30.9 Disorder of puberty, unspecified
0.000 0.996 0.004
E30.8 Other disorders of puberty
0.000 0.996 0.004
E30.1 Precocious puberty
0.000 0.996 0.004
E30.0 Delayed puberty
0.000 0.996 0.004
E32.9 Disease of thymus, unspecified
0.000 0.996 0.004
E32.8 Other diseases of thymus
0.000 0.996 0.004
E32.1 Abscess of thymus
0.000 0.996 0.004
E32.0 Persistent hyperplasia of thymus
0.000 0.996 0.004
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.996 0.004
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.996 0.004
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.996 0.004
T40.4 Other synthetic narcotics
0.004 0.996 0.000
I61 Intracerebral haemorrhage
0.004 0.996 0.000
E22.1 Hyperprolactinaemia
0.000 0.996 0.004
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.000 0.996 0.004
N70.1 Chronic salpingitis and oophoritis
0.004 0.996 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.996 0.004
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.004 0.996 0.000
T40.8 Lysergide [LSD]
0.004 0.996 0.000
T40.7 Cannabis (derivatives)
0.004 0.996 0.000
T40.0 Opium
0.004 0.996 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.996 0.004
E25.8 Other adrenogenital disorders
0.000 0.996 0.004
K85.9 Acute pancreatitis, unspecified
0.000 0.996 0.004
E20.1 Pseudohypoparathyroidism
0.000 0.996 0.004
E20.0 Idiopathic hypoparathyroidism
0.000 0.996 0.004
E34.9 Endocrine disorder, unspecified
0.000 0.996 0.004
E23.1 Drug-induced hypopituitarism
0.000 0.996 0.004
M54.29 Cervicalgia-Site unspe
0.004 0.996 0.000
D33.4 Spinal cord
0.004 0.996 0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.004 0.996 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.004 0.996 0.000
M96.5 Postradiation scoliosis
0.000 0.996 0.004
E28.9 Ovarian dysfunction, unspecified
0.000 0.996 0.004
E28.8 Other ovarian dysfunction
0.000 0.996 0.004
E28.1 Androgen excess
0.000 0.996 0.004
E28.0 Oestrogen excess
0.000 0.996 0.004
E34.5 Androgen resistance syndrome
0.000 0.996 0.004
E34.4 Constitutional tall stature
0.000 0.996 0.004
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.996 0.004
E34.1 Other hypersecretion of intestinal hormones
0.000 0.996 0.004
D80-D89 Certain disorders involving the immune mechanism
0.004 0.996 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.004 0.996 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.004 0.996 0.000
M54.82 Other dorsalgia (Cervical region)
0.004 0.996 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.004 0.996 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.996 0.004
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.996 0.004
E21.3 Hyperparathyroidism, unspecified
0.000 0.996 0.004
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.996 0.004
E24.3 Ectopic ACTH syndrome
0.000 0.996 0.004
E24.1 Nelson's syndrome
0.000 0.996 0.004
M54.28 Cervicalgia-Sacral/sacrococ
0.004 0.996 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.996 0.004
E24.8 Other Cushing's syndrome
0.000 0.996 0.004
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.004 0.996 0.000
T40.1 Heroin
0.004 0.996 0.000
L81.4 Other melanin hyperpigmentation
0.004 0.996 0.000
E28.2 Polycystic ovarian syndrome
0.000 0.996 0.004
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.004 0.996 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.003 0.996 0.000
D33.3 Cranial nerves
0.004 0.996 0.000
E26.0 Primary hyperaldosteronism
0.000 0.996 0.004
T40.5 Cocaine
0.004 0.996 0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)
0.000 0.996 0.003
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate
0.000 0.996 0.003
E20.8 Other hypoparathyroidism
0.000 0.996 0.003
E28.3 Primary ovarian failure
0.000 0.996 0.003
I61.9 Intracerebral haemorrhage, unspecified
0.004 0.996 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.000 0.996 0.004
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.004 0.996 0.000
M54.84 Other dorsalgia (Thoracic region)
0.003 0.996 0.000
D33.9 Central nervous system, unspecified
0.003 0.996 0.000
D33.7 Other specified parts of central nervous system
0.003 0.996 0.000
D33.1 Brain, infratentorial
0.003 0.996 0.000
D80 Immunodeficiency with predominantly antibody defects
0.004 0.996 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.996 0.003
K92.0 Haematemesis
0.004 0.996 0.000
T40.6 Other and unspecified narcotics
0.003 0.996 0.000
E23.0 Hypopituitarism
0.000 0.997 0.003
I61.8 Other intracerebral haemorrhage
0.003 0.997 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.003 0.997 0.001
E34.3 Short stature, not elsewhere classified
0.000 0.997 0.003
D84 Other immunodeficiencies
0.003 0.997 0.000
M54.16 Radiculopathy (Lumbar region)
0.003 0.997 0.000
M54.86 Other dorsalgia (Lumbar region)
0.003 0.997 0.001
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.003 0.997 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.003 0.997 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.000 0.997 0.003
D84.1 Defects in the complement system
0.003 0.997 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.003 0.997 0.000
M54.36 Sciatica (Lumbar region)
0.003 0.997 0.000
I61.3 Intracerebral haemorrhage in brain stem
0.003 0.997 0.000
U89.8 Agent resistant to other single specified antibiotic
0.000 0.997 0.003
D36.7 Other specified sites
0.000 0.997 0.003
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.003 0.997 0.000
E23.2 Diabetes insipidus
0.000 0.997 0.003
E34.0 Carcinoid syndrome
0.000 0.997 0.003
I61.6 Intracerebral haemorrhage, multiple localised
0.003 0.997 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.997 0.003
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.003 0.997 0.000
M54.89 Other dorsalgia (Site unspecified)
0.003 0.997 0.001
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.003 0.997 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.003 0.997 0.000
D35.0 Adrenal gland
0.000 0.997 0.003
D81 Combined immunodeficiencies
0.003 0.997 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.997 0.003
T43.8 Other psychotropic drugs, not elsewhere classified
0.003 0.997 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.003 0.997 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.003 0.997 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.003 0.997 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.003 0.997 0.000
M51 Other intervertebral disk disorders
0.003 0.997 0.000
M54.56 Low back pain (Lumbar region)
0.003 0.997 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.003 0.997 0.000
T43.6 Psychostimulants with abuse potential
0.003 0.997 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.003 0.997 0.000
M93.9 Osteochondropathy, unspecified
0.003 0.997 0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.003 0.997 0.000
T43.9 Psychotropic drug, unspecified
0.003 0.997 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.000 0.997 0.003
I61.5 Intracerebral haemorrhage, intraventricular
0.003 0.997 0.000
M65.8 Other synovitis and tenosynovitis
0.000 0.997 0.003
M99 Biomechanical lesions, not elsewhere classified
0.000 0.997 0.003
D80.1 Nonfamilial hypogammaglobulinaemia
0.003 0.997 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.003 0.997 0.000
D89.1 Cryoglobulinaemia
0.003 0.997 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.003 0.997 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.003 0.997 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.003 0.997 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.003 0.997 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.003 0.997 0.000
J95.8 Other postprocedural respiratory disorders
0.000 0.997 0.003
K85 Acute pancreatitis
0.000 0.997 0.003
T41 Poisoning by anaesthetics and therapeutic gases
0.003 0.997 0.000
D46.2 Refractory anaemia with excess of blasts
0.000 0.997 0.003
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.003 0.997 0.000
T50.8 Diagnostic agents
0.003 0.997 0.000
D82 Immunodeficiency associated with other major defects
0.003 0.997 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.003 0.997 0.000
K85.1 Biliary acute pancreatitis
0.000 0.997 0.003
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.003 0.997 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.003 0.997 0.000
K92.9 Disease of digestive system, unspecified
0.003 0.997 0.000
T39.4 Antirheumatics, not elsewhere classified
0.003 0.997 0.000
T39.2 Pyrazolone derivatives
0.003 0.997 0.000
D83 Common variable immunodeficiency
0.003 0.997 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.003 0.997 0.000
M99.53 Intervertebral disc stenosis of neural canal (Lumbar region)
0.000 0.997 0.003
D89.3 Immune reconstitution syndrome
0.003 0.997 0.000
K85.8 Other acute pancreatitis
0.000 0.997 0.003
M95.0 Acquired deformity of nose
0.000 0.997 0.003
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.003 0.997 0.000
M99.5 Intervertebral disk stenosis of neural canal
0.000 0.997 0.002
D46 Myelodysplastic syndromes
0.000 0.997 0.003
D84.8 Other specified immunodeficiencies
0.002 0.997 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.002 0.997 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.002 0.997 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.002 0.997 0.000
T45.5 Anticoagulants
0.002 0.997 0.000
T50.7 Analeptics and opioid receptor antagonists
0.002 0.997 0.000
T50.5 Appetite depressants
0.002 0.997 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.002 0.997 0.000
T50.0 Mineralocorticoids and their antagonists
0.002 0.997 0.000
T51.0 Ethanol
0.003 0.997 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.003 0.997 0.000
D84.9 Immunodeficiency, unspecified
0.002 0.997 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.002 0.997 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.002 0.997 0.000
D81.9 Combined immunodeficiency, unspecified
0.002 0.997 0.000
D81.8 Other combined immunodeficiencies
0.002 0.997 0.000
D81.7 Major histocompatibility complex class II deficiency
0.002 0.997 0.000
D81.6 Major histocompatibility complex class I deficiency
0.002 0.997 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.002 0.997 0.000
D81.4 Nezelof's syndrome
0.002 0.997 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.002 0.997 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.002 0.997 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.002 0.997 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.002 0.997 0.000
Z04.3 Examination and observation following other accident
0.003 0.997 0.000
M95.4 Acquired deformity of chest and rib
0.000 0.998 0.002
M65 Synovitis and tenosynovitis
0.000 0.998 0.002
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.002 0.998 0.000
T50.1 Loop [high-ceiling] diuretics
0.002 0.998 0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)
0.002 0.998 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.002 0.998 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.002 0.998 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.002 0.998 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.998 0.002
K85.0 Idiopathic acute pancreatitis
0.000 0.998 0.002
T47.2 Stimulant laxatives
0.002 0.998 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.998 0.002
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.002 0.998 0.000
T37.5 Antiviral drugs
0.002 0.998 0.000
T37.4 Anthelminthics
0.002 0.998 0.000
T37.3 Other antiprotozoal drugs
0.002 0.998 0.000
T37.1 Antimycobacterial drugs
0.002 0.998 0.000
T37.0 Sulphonamides
0.002 0.998 0.000
N70 Salpingitis and oophoritis
0.002 0.998 0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)
0.000 0.998 0.002
M06.0 Seronegative rheumatoid arthritis
0.000 0.998 0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.002 0.998 0.000
T50.4 Drugs affecting uric acid metabolism
0.002 0.998 0.000
M51.9 Intervertebral disk disorder, unspecified
0.002 0.998 0.000
M65.83 Other synovitis and tenosynovitis (Forearm)
0.000 0.998 0.002
M51.4 Schmorl's nodes
0.002 0.998 0.000
M99.8 Other biomechanical lesions
0.000 0.998 0.002
T41.2 Other and unspecified general anaesthetics
0.002 0.998 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.002 0.998 0.000
E55.9 Vitamin D deficiency, unspecified
0.002 0.998 0.000
M51.3 Other specified intervertebral disk degeneration
0.002 0.998 0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified
0.000 0.998 0.002
M95.8 Other specified acquired deformities of musculoskeletal system
0.000 0.998 0.002
M95.5 Acquired deformity of pelvis
0.000 0.998 0.002
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.000 0.998 0.002
M65.88 Other synovitis and tenosynovitis (Other)
0.000 0.998 0.002
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.000 0.998 0.002
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.000 0.998 0.002
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.000 0.998 0.002
M99.9 Biomechanical lesion, unspecified
0.000 0.998 0.002
M99.6 Osseous and subluxation stenosis of intervertebral foramina
0.000 0.998 0.002
M99.4 Connective tissue stenosis of neural canal
0.000 0.998 0.002
M99.3 Osseous stenosis of neural canal
0.000 0.998 0.002
M99.2 Subluxation stenosis of neural canal
0.000 0.998 0.002
M99.1 Subluxation complex (vertebral)
0.000 0.998 0.002
M99.0 Segmental and somatic dysfunction
0.000 0.998 0.002
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.002 0.998 0.000
M95.3 Acquired deformity of neck
0.000 0.998 0.002
T47.6 Antidiarrhoeal drugs
0.002 0.998 0.000
T49.9 Topical agent, unspecified
0.002 0.998 0.000
T49.8 Other topical agents
0.002 0.998 0.000
T49.7 Dental drugs, topically applied
0.002 0.998 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.002 0.998 0.000
T49.5 Ophthalmological drugs and preparations
0.002 0.998 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.002 0.998 0.000
T49.3 Emollients, demulcents and protectants
0.002 0.998 0.000
T49.2 Local astringents and local detergents
0.002 0.998 0.000
T49.1 Antipruritics
0.002 0.998 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.998 0.002
D82.9 Immunodeficiency associated with major defect, unspecified
0.002 0.998 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.002 0.998 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.002 0.998 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.002 0.998 0.000
D82.2 Immunodeficiency with short-limbed stature
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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