TreeWAS – Variant ID: rs10958476

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G81.9 Hemiplegia, unspecified	0.072	0.928	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.059	0.941	0.000
G81 Hemiplegia	0.045	0.955	0.000
I69 Sequelae of cerebrovascular disease	0.044	0.956	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.039	0.961	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.038	0.962	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.038	0.962	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.037	0.963	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.037	0.963	0.000
Y45.1 Salicylates	0.037	0.963	0.000
Y57 Other and unspecified drugs and medicaments	0.037	0.963	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.036	0.964	0.000
Y44 Agents primarily affecting blood constituents	0.035	0.965	0.000
Y57.9 Drug or medicament, unspecified	0.034	0.966	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.034	0.966	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.033	0.967	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.033	0.967	0.000
Y52 Agents primarily affecting the cardiovascular system	0.033	0.967	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.033	0.967	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.033	0.967	0.000
Y57.5 X-ray contrast media	0.033	0.967	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.033	0.967	0.000
G81.0 Flaccid hemiplegia	0.032	0.968	0.000
Y45.5 4-Aminophenol derivatives	0.032	0.968	0.000
Y44.5 Thrombolytic drugs	0.032	0.968	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.031	0.969	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.031	0.969	0.000
Y46.4 Iminostilbenes	0.031	0.969	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.030	0.970	0.000
G81.1 Spastic hemiplegia	0.030	0.970	0.000
I64 Stroke, not specified as haemorrhage or infarction	0.030	0.970	0.000
Y45.8 Other analgesics and antipyretics	0.030	0.970	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.030	0.970	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.029	0.971	0.000
Y59 Other and unspecified vaccines and biological substances	0.028	0.971	0.000
Y58 Bacterial vaccines	0.028	0.972	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.028	0.972	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.028	0.972	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.028	0.972	0.000
Y45.4 Antirheumatics	0.027	0.972	0.000
I60-I69 Cerebrovascular diseases	0.028	0.972	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.027	0.973	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.027	0.973	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.027	0.973	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.027	0.973	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.027	0.973	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.027	0.973	0.000
Y51.0 Anticholinesterase agents	0.027	0.973	0.000
Y45.2 Propionic acid derivatives	0.027	0.973	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.027	0.973	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.027	0.973	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.027	0.973	0.000
Y54.4 Loop [high-ceiling] diuretics	0.026	0.973	0.000
Y57.7 Vitamins, not elsewhere classified	0.026	0.973	0.000
Y57.4 Pharmaceutical excipients	0.026	0.973	0.000
Y57.3 Alcohol deterrents	0.026	0.973	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.026	0.973	0.000
Y57.1 Lipotropic drugs	0.026	0.973	0.000
Y57.0 Appetite depressants [anorectics]	0.026	0.973	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.027	0.973	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.026	0.973	0.000
Y45.0 Opioids and related analgesics	0.027	0.973	0.000
Y54.3 Benzothiadiazine derivatives	0.026	0.974	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.026	0.974	0.000
Y56.9 Topical agent, unspecified	0.026	0.974	0.000
Y56.8 Other topical agents	0.026	0.974	0.000
Y56.7 Dental drugs, topically applied	0.026	0.974	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.026	0.974	0.000
Y56.5 Ophthalmological drugs and preparations	0.026	0.974	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.026	0.974	0.000
Y56.3 Emollients, demulcents and protectants	0.026	0.974	0.000
Y56.2 Local astringents and local detergents	0.026	0.974	0.000
Y56.1 Antipruritics	0.026	0.974	0.000
Y52.1 Calcium-channel blockers	0.025	0.975	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.025	0.975	0.000
Y44.7 Plasma substitutes	0.025	0.975	0.000
Y44.6 Natural blood and blood products	0.025	0.975	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.025	0.975	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.025	0.975	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.025	0.975	0.000
Y54.8 Agents affecting uric acid metabolism	0.025	0.975	0.000
Y44.2 Anticoagulants	0.025	0.975	0.000
Y53.4 Other laxatives	0.025	0.975	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.025	0.975	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.024	0.975	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.024	0.976	0.000
Y46.8 Antispasticity drugs	0.024	0.976	0.000
Y46.7 Anti-Parkinsonism drugs	0.024	0.976	0.000
Y46.5 Valproic acid	0.024	0.976	0.000
Y46.3 Deoxybarbiturates	0.024	0.976	0.000
Y46.1 Oxazolidinediones	0.024	0.976	0.000
Y46.0 Succinimides	0.024	0.976	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.024	0.976	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.024	0.976	0.000
Y52.7 Peripheral vasodilators	0.024	0.976	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.024	0.976	0.000
Y54.9 Mineral salts, not elsewhere classified	0.024	0.976	0.000
Y54.7 Agents affecting calcification	0.024	0.976	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.024	0.976	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.024	0.976	0.000
Y54.0 Mineralocorticoids	0.024	0.976	0.000
G80 Infantile cerebral palsy	0.024	0.976	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.024	0.976	0.000
Y57.8 Other drugs and medicaments	0.023	0.976	0.000
G82 Paraplegia and tetraplegia	0.023	0.977	0.000
Y48 Anaesthetics and therapeutic gases	0.023	0.977	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.023	0.977	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.023	0.977	0.000
Y46.2 Hydantoin derivatives	0.023	0.977	0.000
Y57.6 Other diagnostic agents	0.023	0.977	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.022	0.977	0.000
Y53.7 Emetics	0.022	0.977	0.000
Y53.6 Antidiarrhoeal drugs	0.022	0.977	0.000
Y53.5 Digestants	0.022	0.977	0.000
Y53.3 Saline and osmotic laxatives	0.022	0.977	0.000
Y53.2 Stimulant laxatives	0.022	0.977	0.000
Y53.0 Histamine H2-receptor antagonists	0.022	0.977	0.000
Y46.6 Other and unspecified antiepileptics	0.022	0.978	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.022	0.978	0.000
G82.5 Tetraplegia, unspecified	0.022	0.978	0.000
Y41.0 Sulphonamides	0.021	0.978	0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.022	0.978	0.000
Y59.3 Immunoglobulin	0.021	0.979	0.000
Y59.9 Vaccine or biological substance, unspecified	0.021	0.979	0.000
Y59.8 Other specified vaccines and biological substances	0.021	0.979	0.000
Y59.2 Protozoal vaccines	0.021	0.979	0.000
Y59.1 Rickettsial vaccines	0.021	0.979	0.000
Y59.0 Viral vaccines	0.021	0.979	0.000
Y42.1 Thyroid hormones and substitutes	0.021	0.979	0.000
Y50.9 Central nervous system stimulant, unspecified	0.020	0.979	0.000
Y50.8 Other central nervous system stimulants	0.020	0.979	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.020	0.979	0.000
Y50.1 Opioid receptor antagonists	0.020	0.979	0.000
Y50.0 Analeptics	0.020	0.979	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.020	0.979	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.020	0.979	0.000
Y55.5 Anticommon cold drugs	0.020	0.979	0.000
Y55.4 Expectorants	0.020	0.979	0.000
Y55.3 Antitussives	0.020	0.979	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.020	0.979	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.020	0.979	0.000
Y55.0 Oxytocic drugs	0.020	0.979	0.000
Y58.9 Other and unspecified bacterial vaccines	0.020	0.979	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.020	0.979	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.020	0.979	0.000
Y58.5 Diphtheria vaccine	0.020	0.979	0.000
Y58.4 Tetanus vaccine	0.020	0.979	0.000
Y58.3 Plague vaccine	0.020	0.979	0.000
Y58.2 Cholera vaccine	0.020	0.979	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.020	0.979	0.000
Y58.0 BCG vaccine	0.020	0.979	0.000
Y41.1 Antimycobacterial drugs	0.020	0.979	0.000
G80.9 Infantile cerebral palsy, unspecified	0.020	0.980	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.020	0.980	0.000
Y42.2 Antithyroid drugs	0.020	0.980	0.000
G82.2 Paraplegia, unspecified	0.020	0.980	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.020	0.980	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.019	0.981	0.000
Y41.4 Anthelminthics	0.019	0.981	0.000
Y41.3 Other antiprotozoal drugs	0.019	0.981	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.019	0.981	0.000
Y42.9 Other and unspecified hormone antagonists	0.019	0.981	0.000
Y42.4 Oral contraceptives	0.019	0.981	0.000
I65.2 Occlusion and stenosis of carotid artery	0.019	0.981	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.019	0.981	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.019	0.981	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.019	0.981	0.000
Y47.4 Bromine compounds	0.019	0.981	0.000
Y47.3 Paraldehyde	0.019	0.981	0.000
Y47.2 Chloral derivatives	0.019	0.981	0.000
Y47.0 Barbiturates, not elsewhere classified	0.019	0.981	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.019	0.981	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.018	0.981	0.000
I61 Intracerebral haemorrhage	0.019	0.981	0.000
G61 Inflammatory polyneuropathy	0.019	0.981	0.000
G80.0 Spastic cerebral palsy	0.018	0.982	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.018	0.982	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.018	0.982	0.000
G80.1 Spastic diplegia	0.018	0.982	0.000
G61.0 Guillain-Barre syndrome	0.018	0.982	0.000
S42.40 Fracture of lower end of humerus (closed)	0.018	0.982	0.000
G80.8 Other infantile cerebral palsy	0.017	0.983	0.000
G80.4 Ataxic cerebral palsy	0.017	0.983	0.000
G80.3 Dyskinetic cerebral palsy	0.017	0.983	0.000
G80.2 Infantile hemiplegia	0.017	0.983	0.000
G60 Hereditary and idiopathic neuropathy	0.017	0.983	0.000
Y47.1 Benzodiazepines	0.017	0.983	0.000
G82.3 Flaccid tetraplegia	0.017	0.983	0.000
G82.0 Flaccid paraplegia	0.017	0.983	0.000
Y48.5 Therapeutic gases	0.017	0.983	0.000
Y48.1 Parenteral anaesthetics	0.017	0.983	0.000
Y48.0 Inhaled anaesthetics	0.017	0.983	0.000
Y48.2 Other and unspecified general anaesthetics	0.017	0.983	0.000
Y41.5 Antiviral drugs	0.017	0.983	0.000
I62 Other nontraumatic intracranial haemorrhage	0.017	0.983	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.016	0.983	0.000
I61.9 Intracerebral haemorrhage, unspecified	0.017	0.983	0.000
Y42.5 Other oestrogens and progestogens	0.016	0.984	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.016	0.984	0.000
G61.8 Other inflammatory polyneuropathies	0.016	0.984	0.000
G50.0 Trigeminal neuralgia	0.016	0.984	0.000
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.016	0.984	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.016	0.984	0.000
I65.1 Occlusion and stenosis of basilar artery	0.016	0.984	0.000
Y48.3 Local anaesthetics	0.015	0.985	0.000
G62.8 Other specified polyneuropathies	0.015	0.985	0.000
Y54.5 Other diuretics	0.015	0.985	0.000
S80.9 Superficial injury of lower leg, unspecified	0.015	0.985	0.000
I68.0 Cerebral amyloid angiopathy	0.015	0.985	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.015	0.985	0.000
G62 Other polyneuropathies	0.015	0.985	0.000
Y43 Primarily systemic agents	0.015	0.985	0.000
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.015	0.985	0.000
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.015	0.985	0.000
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.015	0.985	0.000
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.015	0.985	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.015	0.985	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.015	0.985	0.000
I63 Cerebral infarction	0.015	0.985	0.000
I61.3 Intracerebral haemorrhage in brain stem	0.014	0.985	0.000
Y48.4 Anaesthetic, unspecified	0.014	0.985	0.000
I67 Other cerebrovascular diseases	0.015	0.985	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.014	0.985	0.000
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.014	0.986	0.000
I66.8 Occlusion and stenosis of other cerebral artery	0.014	0.986	0.000
I66.3 Occlusion and stenosis of cerebellar arteries	0.014	0.986	0.000
I66.2 Occlusion and stenosis of posterior cerebral artery	0.014	0.986	0.000
I66.1 Occlusion and stenosis of anterior cerebral artery	0.014	0.986	0.000
I66.0 Occlusion and stenosis of middle cerebral artery	0.014	0.986	0.000
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.014	0.986	0.000
G82.1 Spastic paraplegia	0.014	0.986	0.000
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.014	0.986	0.000
Y49.9 Psychotropic drug, unspecified	0.013	0.986	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.013	0.986	0.000
Y49.7 Psychostimulants with abuse potential	0.013	0.986	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.013	0.986	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.013	0.986	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.013	0.986	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.013	0.986	0.000
G61.1 Serum neuropathy	0.013	0.986	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.013	0.987	0.000
I65.0 Occlusion and stenosis of vertebral artery	0.013	0.987	0.000
G64 Other disorders of peripheral nervous system	0.013	0.987	0.000
S42.4 Fracture of lower end of humerus	0.013	0.987	0.000
G60.0 Hereditary motor and sensory neuropathy	0.013	0.987	0.000
G50 Disorders of trigeminal nerve	0.013	0.987	0.000
I61.8 Other intracerebral haemorrhage	0.013	0.987	0.000
I60 Subarachnoid haemorrhage	0.013	0.987	0.000
S43.0 Dislocation of shoulder joint	0.013	0.987	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.012	0.987	0.000
G60.3 Idiopathic progressive neuropathy	0.012	0.987	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.012	0.987	0.000
G60.1 Refsum's disease	0.012	0.987	0.000
I67.1 Cerebral aneurysm, nonruptured	0.012	0.988	0.000
G63.2 Diabetic polyneuropathy	0.012	0.988	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.012	0.988	0.000
I62.1 Nontraumatic extradural haemorrhage	0.012	0.988	0.000
S80 Superficial injury of lower leg	0.012	0.988	0.000
G62.0 Drug-induced polyneuropathy	0.012	0.988	0.000
G82.4 Spastic tetraplegia	0.012	0.988	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.012	0.988	0.000
Chapter VI Diseases of the nervous system	0.012	0.988	0.000
Y42.7 Androgens and anabolic congeners	0.012	0.988	0.000
Z29.1 Prophylactic immunotherapy	0.012	0.988	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.012	0.988	0.000
Z29 Need for other prophylactic measures	0.012	0.988	0.000
Y49.2 Other and unspecified antidepressants	0.011	0.989	0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.011	0.989	0.000
S80.8 Other superficial injuries of lower leg	0.011	0.989	0.000
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.011	0.989	0.000
I67.0 Dissection of cerebral arteries, nonruptured	0.011	0.989	0.000
Z29.2 Other prophylactic chemotherapy	0.011	0.989	0.000
Y43.1 Antineoplastic antimetabolites	0.011	0.989	0.000
S42 Fracture of shoulder and upper arm	0.011	0.989	0.000
G62.2 Polyneuropathy due to other toxic agents	0.011	0.989	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.011	0.989	0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.011	0.989	0.000
Y43.9 Primarily systemic agent, unspecified	0.011	0.989	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.011	0.989	0.000
Y43.6 Enzymes, not elsewhere classified	0.011	0.989	0.000
Y43.5 Acidifying and alkalising agents	0.011	0.989	0.000
Y43.2 Antineoplastic natural products	0.011	0.989	0.000
I61.4 Intracerebral haemorrhage in cerebellum	0.011	0.989	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.011	0.989	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.011	0.989	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.011	0.989	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.011	0.989	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.011	0.989	0.000
G63.1 Polyneuropathy in neoplastic disease	0.011	0.989	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
I63.8 Other cerebral infarction	0.011	0.989	0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.011	0.989	0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.011	0.989	0.000
I67.7 Cerebral arteritis, not elsewhere classified	0.011	0.989	0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.011	0.989	0.000
I67.5 Moyamoya disease	0.011	0.989	0.000
I67.4 Hypertensive encephalopathy	0.011	0.989	0.000
I67.3 Progressive vascular leukoencephalopathy	0.011	0.989	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.010	0.989	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.011	0.989	0.000
S40-S49 Injuries to the shoulder and upper arm	0.011	0.989	0.000
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.010	0.989	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.010	0.990	0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.010	0.990	0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.010	0.990	0.000
Y43.0 Antiallergic and antiemetic drugs	0.010	0.990	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.010	0.990	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.010	0.990	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.010	0.990	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.010	0.990	0.000
G50.8 Other disorders of trigeminal nerve	0.010	0.990	0.000
W17 Other fall from one level to another	0.010	0.990	0.000
G57 Mononeuropathies of lower limb	0.010	0.990	0.000
Z29.8 Other specified prophylactic measures	0.010	0.990	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.010	0.990	0.000
S80.7 Multiple superficial injuries of lower leg	0.010	0.990	0.000
G57.8 Other mononeuropathies of lower limb	0.010	0.990	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.010	0.990	0.000
S42.2 Fracture of upper end of humerus	0.010	0.990	0.000
W17.4 Street and highway	0.010	0.990	0.000
M80 Osteoporosis with pathological fracture	0.009	0.991	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.009	0.991	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.009	0.991	0.000
I67.2 Cerebral atherosclerosis	0.009	0.991	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.009	0.991	0.000
G62.1 Alcoholic polyneuropathy	0.009	0.991	0.000
S41 Open wound of shoulder and upper arm	0.009	0.991	0.000
Y49.5 Other antipsychotics and neuroleptics	0.009	0.991	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.009	0.991	0.000
G83 Other paralytic syndromes	0.009	0.991	0.001
G20-G26 Extrapyramidal and movement disorders	0.009	0.991	0.000
W17.3 Sports and athletics area	0.009	0.991	0.000
W00-W19 Falls	0.009	0.991	0.000
S80.0 Contusion of knee	0.009	0.991	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.009	0.991	0.000
S43.1 Dislocation of acromioclavicular joint	0.009	0.991	0.000
Z29.0 Isolation	0.009	0.991	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.009	0.991	0.000
G57.6 Lesion of plantar nerve	0.009	0.991	0.000
S41.1 Open wound of upper arm	0.009	0.991	0.000
S42.20 Fracture of upper end of humerus (closed)	0.009	0.991	0.000
M80.8 Other osteoporosis with pathological fracture	0.009	0.991	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.009	0.991	0.000
G50.1 Atypical facial pain	0.008	0.991	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.008	0.991	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.008	0.991	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.008	0.991	0.000
S43.2 Dislocation of sternoclavicular joint	0.008	0.991	0.000
Z29.9 Prophylactic measure, unspecified	0.008	0.991	0.000
S42.1 Fracture of scapula	0.008	0.992	0.000
W17.5 Trade and service area	0.008	0.992	0.000
G24 Dystonia	0.008	0.992	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.008	0.992	0.000
S40 Superficial injury of shoulder and upper arm	0.008	0.992	0.000
S43.4 Sprain and strain of shoulder joint	0.008	0.992	0.000
G53 Cranial nerve disorders in diseases classified elsewhere	0.008	0.992	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.008	0.992	0.000
I67.8 Other specified cerebrovascular diseases	0.008	0.992	0.000
S42.41 Fracture of lower end of humerus (open)	0.008	0.992	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.008	0.992	0.000
G54 Nerve root and plexus disorders	0.008	0.992	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.008	0.992	0.000
G57.5 Tarsal tunnel syndrome	0.008	0.992	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.008	0.992	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.008	0.992	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.008	0.992	0.000
Chapter XX External causes of morbidity and mortality	0.008	0.992	0.000
G24.9 Dystonia, unspecified	0.008	0.992	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.008	0.992	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.008	0.992	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.008	0.992	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.008	0.992	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.008	0.992	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.008	0.992	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.008	0.992	0.000
S48 Traumatic amputation of shoulder and upper arm	0.008	0.992	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.008	0.992	0.000
S44 Injury of nerves at shoulder and upper arm level	0.008	0.992	0.000
S47 Crushing injury of shoulder and upper arm	0.008	0.992	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.008	0.992	0.000
Y00-Y09 Assault	0.008	0.992	0.000
G57.1 Meralgia paraesthetica	0.008	0.992	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.008	0.992	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.008	0.992	0.000
W05 Fall involving wheelchair	0.008	0.992	0.000
W14 Fall from tree	0.008	0.992	0.000
I69.3 Sequelae of cerebral infarction	0.007	0.992	0.001
S40.0 Contusion of shoulder and upper arm	0.008	0.992	0.000
W17.6 Industrial and construction area	0.008	0.992	0.000
W17.2 School, other institution and public administrative area	0.007	0.992	0.000
W07 Fall involving chair	0.008	0.992	0.000
W17.9 Unspecified place	0.007	0.992	0.000
W17.8 Other specified place	0.007	0.992	0.000
W17.0 Home	0.007	0.992	0.000
W17.7 Farm	0.007	0.992	0.000
W17.1 Residential institution	0.007	0.992	0.000
A87.9 Viral meningitis, unspecified	0.007	0.993	0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.007	0.993	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.007	0.993	0.000
G57.4 Lesion of medial popliteal nerve	0.007	0.993	0.000
G57.2 Lesion of femoral nerve	0.007	0.993	0.000
G70-G73 Diseases of myoneural junction and muscle	0.007	0.993	0.000
W19.9 Unspecified place	0.007	0.993	0.000
M80-M85 Disorders of bone density and structure	0.007	0.993	0.000
Y04 Assault by bodily force	0.007	0.993	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.007	0.993	0.000
W00 Fall on same level involving ice and snow	0.007	0.993	0.000
S46.3 Injury of muscle and tendon of triceps	0.007	0.993	0.000
G54.1 Lumbosacral plexus disorders	0.007	0.993	0.000
I60.8 Other subarachnoid haemorrhage	0.007	0.993	0.000
G23 Other degenerative diseases of basal ganglia	0.007	0.993	0.000
S42.21 Fracture of upper end of humerus (open)	0.007	0.993	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.007	0.993	0.000
Y43.3 Other antineoplastic drugs	0.007	0.993	0.000
W08 Fall involving other furniture	0.007	0.993	0.000
G54.8 Other nerve root and plexus disorders	0.007	0.993	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.007	0.993	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.007	0.993	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.007	0.993	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.007	0.993	0.000
G51 Facial nerve disorders	0.007	0.993	0.000
G53.0 Postzoster neuralgia	0.007	0.993	0.000
M85 Other disorders of bone density and structure	0.007	0.993	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.007	0.993	0.000
W19 Unspecified fall	0.007	0.993	0.000
V20-V29 Motorcycle rider injured in transport accident	0.007	0.993	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.007	0.993	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.007	0.993	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.007	0.993	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.007	0.993	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.007	0.993	0.000
G83.5 Locked-in syndrome	0.006	0.993	0.001
G83.3 Monoplegia, unspecified	0.006	0.993	0.001
G83.0 Diplegia of upper limbs	0.006	0.993	0.001
S42.9 Fracture of shoulder girdle, part unspecified	0.007	0.993	0.000
G21 Secondary Parkinsonism	0.007	0.993	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.007	0.993	0.000
G22 Parkinsonism in diseases classified elsewhere	0.007	0.993	0.000
G10 Huntington's disease	0.007	0.993	0.000
G57.0 Lesion of sciatic nerve	0.007	0.993	0.000
G83.2 Monoplegia of upper limb	0.006	0.993	0.000
Y04.8 Other specified place	0.007	0.993	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.007	0.993	0.000
W12 Fall on and from scaffolding	0.007	0.993	0.000
W09 Fall involving playground equipment	0.007	0.993	0.000
W04 Fall while being carried or supported by other persons	0.007	0.993	0.000
G24.3 Spasmodic torticollis	0.007	0.993	0.000
W07.9 Unspecified place	0.007	0.993	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.007	0.993	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.007	0.993	0.000
W15 Fall from cliff	0.007	0.993	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.007	0.993	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.006	0.993	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.007	0.993	0.000
X00-X09 Exposure to smoke, fire and flames	0.007	0.993	0.000
S42.10 Fracture of scapula (closed)	0.007	0.993	0.000
M81 Osteoporosis without pathological fracture	0.007	0.993	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.006	0.993	0.000
M87.9 Osteonecrosis, unspecified	0.007	0.993	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.006	0.993	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.006	0.993	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.006	0.993	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.006	0.993	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.006	0.993	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.006	0.993	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.006	0.993	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.006	0.993	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.006	0.993	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.006	0.993	0.000
G83.1 Monoplegia of lower limb	0.006	0.993	0.001
G59 Mononeuropathy in diseases classified elsewhere	0.006	0.993	0.000
G24.8 Other dystonia	0.006	0.994	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.006	0.994	0.000
W14.9 Unspecified place	0.006	0.994	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.006	0.994	0.000
G06.0 Intracranial abscess and granuloma	0.006	0.994	0.000
W44.0 Home	0.006	0.994	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.006	0.994	0.000
W05.9 Unspecified place	0.006	0.994	0.000
M85.8 Other specified disorders of bone density and structure	0.006	0.994	0.000
Y00 Assault by blunt object	0.006	0.994	0.000
S42.11 Fracture of scapula (open)	0.006	0.994	0.000
S42.3 Fracture of shaft of humerus	0.006	0.994	0.000
W06 Fall involving bed	0.006	0.994	0.000
G51.9 Disorder of facial nerve, unspecified	0.006	0.994	0.000
W02.9 Unspecified place	0.006	0.994	0.000
W11 Fall on and from ladder	0.006	0.994	0.000
G24.4 Idiopathic orofacial dystonia	0.006	0.994	0.000
G24.2 Idiopathic nonfamilial dystonia	0.006	0.994	0.000
G24.1 Idiopathic familial dystonia	0.006	0.994	0.000
G24.0 Drug-induced dystonia	0.006	0.994	0.000
S42.71 Multiple fractures of clavicle, scapula and humerus (open)	0.006	0.994	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.006	0.994	0.000
G53.8 Other cranial nerve disorders in other diseases classified elsewhere	0.006	0.994	0.000
G53.3 Multiple cranial nerve palsies in neoplastic disease	0.006	0.994	0.000
G53.2 Multiple cranial nerve palsies in sarcoidosis	0.006	0.994	0.000
G53.1 Multiple cranial nerve palsies in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.006	0.994	0.000
W05.0 Home	0.006	0.994	0.000
V01-V09 Pedestrian injured in transport accident	0.006	0.994	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations