TreeWAS – Variant ID: rs10966811

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D23.7 Skin of lower limb, including hip	0.000	0.892	0.108
S22.30 Fracture of rib (closed)	0.017	0.983	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.014	0.986	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.987	0.013
R59.0 Localised enlarged lymph nodes	0.000	0.987	0.013
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.988	0.012
Y52 Agents primarily affecting the cardiovascular system	0.000	0.989	0.011
M54.22 Cervicalgia (Cervical region)	0.000	0.989	0.011
E27.8 Other specified disorders of adrenal gland	0.011	0.989	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.990	0.010
L05.0 Pilonidal cyst with abscess	0.000	0.990	0.010
E27 Other disorders of adrenal gland	0.010	0.990	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.991	0.009
E27.2 Addisonian crisis	0.009	0.991	0.000
Y52.1 Calcium-channel blockers	0.000	0.991	0.009
Z48.0 Attention to surgical dressings and sutures	0.000	0.991	0.009
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.991	0.009
M81.9 Osteoporosis, unspecified	0.009	0.991	0.000
E27.1 Primary adrenocortical insufficiency	0.008	0.992	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.992	0.008
M81.98 Osteoporosis, unspecified (Other)	0.008	0.992	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.992	0.008
Y52.7 Peripheral vasodilators	0.000	0.992	0.008
N28.0 Ischaemia and infarction of kidney	0.000	0.992	0.008
M81.96 Osteoporosis, unspecified (Lower leg)	0.008	0.992	0.000
K11.2 Sialoadenitis	0.000	0.992	0.008
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.992	0.008
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.993	0.007
S22.3 Fracture of rib	0.007	0.993	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.993	0.007
E27.3 Drug-induced adrenocortical insufficiency	0.007	0.993	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.007	0.993	0.000
E27.5 Adrenomedullary hyperfunction	0.007	0.993	0.000
E27.0 Other adrenocortical overactivity	0.007	0.993	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.006	0.993	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.006	0.993	0.000
K11.1 Hypertrophy of salivary gland	0.000	0.993	0.007
E27.4 Other and unspecified adrenocortical insufficiency	0.006	0.994	0.000
E27.9 Disorder of adrenal gland, unspecified	0.006	0.994	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.006	0.994	0.000
K11 Diseases of salivary glands	0.000	0.994	0.006
M81.93 Osteoporosis, unspecified (Forearm)	0.006	0.994	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.006	0.994	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.994	0.006
M10.96 Gout, unspecified (Lower leg)	0.000	0.994	0.006
S22.31 Fracture of rib (open)	0.005	0.994	0.000
K11.6 Mucocele of salivary gland	0.000	0.994	0.005
J69.0 Pneumonitis due to food and vomit	0.005	0.995	0.000
K11.9 Disease of salivary gland, unspecified	0.000	0.995	0.005
Z48.9 Surgical follow-up care, unspecified	0.000	0.995	0.005
E11.5 With peripheral circulatory complications	0.005	0.995	0.000
L05 Pilonidal cyst	0.000	0.995	0.005
Z48 Other surgical follow-up care	0.000	0.995	0.005
E34 Other endocrine disorders	0.005	0.995	0.000
K11.3 Abscess of salivary gland	0.000	0.995	0.005
E20-E35 Disorders of other endocrine glands	0.005	0.995	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.005	0.995	0.000
Z60.2 Living alone	0.005	0.995	0.000
E34.9 Endocrine disorder, unspecified	0.005	0.995	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.995	0.005
K11.4 Fistula of salivary gland	0.000	0.995	0.004
K11.0 Atrophy of salivary gland	0.000	0.995	0.004
E34.8 Other specified endocrine disorders	0.004	0.996	0.000
K11.8 Other diseases of salivary glands	0.000	0.996	0.004
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.996	0.004
E34.3 Short stature, not elsewhere classified	0.004	0.996	0.000
L05.9 Pilonidal cyst without abscess	0.000	0.996	0.004
E28 Ovarian dysfunction	0.004	0.996	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
E28.2 Polycystic ovarian syndrome	0.004	0.996	0.000
R59 Enlarged lymph nodes	0.000	0.996	0.004
M10.90 Gout, unspecified (Multiple sites)	0.000	0.996	0.004
E23 Hypofunction and other disorders of pituitary gland	0.004	0.996	0.000
E32 Diseases of thymus	0.004	0.996	0.000
M10.94 Gout, unspecified (Hand)	0.000	0.996	0.004
E25 Adrenogenital disorders	0.004	0.996	0.000
E34.5 Androgen resistance syndrome	0.004	0.996	0.000
E34.4 Constitutional tall stature	0.004	0.996	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.004	0.996	0.000
E34.1 Other hypersecretion of intestinal hormones	0.004	0.996	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.004	0.996	0.000
E31 Polyglandular dysfunction	0.004	0.996	0.000
E30 Disorders of puberty, not elsewhere classified	0.004	0.996	0.000
K11.7 Disturbances of salivary secretion	0.000	0.996	0.004
M10.9 Gout, unspecified	0.000	0.996	0.004
D23 Other benign neoplasms of skin	0.000	0.996	0.004
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.004	0.996	0.000
O61.0 Failed medical induction of labour	0.004	0.996	0.000
E22 Hyperfunction of pituitary gland	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
E26 Hyperaldosteronism	0.003	0.997	0.000
R22.2 Localised swelling, mass and lump, trunk	0.003	0.997	0.000
E21.2 Other hyperparathyroidism	0.003	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.003	0.997	0.000
A04.5 Campylobacter enteritis	0.000	0.997	0.003
E23.2 Diabetes insipidus	0.003	0.997	0.000
E20 Hypoparathyroidism	0.003	0.997	0.000
E34.0 Carcinoid syndrome	0.003	0.997	0.000
R59.9 Enlarged lymph nodes, unspecified	0.000	0.997	0.003
E32.8 Other diseases of thymus	0.003	0.997	0.000
E03.8 Other specified hypothyroidism	0.003	0.997	0.000
E28.9 Ovarian dysfunction, unspecified	0.003	0.997	0.000
E28.8 Other ovarian dysfunction	0.003	0.997	0.000
E28.1 Androgen excess	0.003	0.997	0.000
E28.0 Oestrogen excess	0.003	0.997	0.000
O03.9 Complete or unspecified, without complication	0.000	0.997	0.003
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.997	0.003
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.003
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.003	0.997	0.000
E23.1 Drug-induced hypopituitarism	0.003	0.997	0.000
E21.4 Other specified disorders of parathyroid gland	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.003	0.997	0.000
D23.6 Skin of upper limb, including shoulder	0.000	0.997	0.003
B18.2 Chronic viral hepatitis C	0.000	0.997	0.003
E32.9 Disease of thymus, unspecified	0.003	0.997	0.000
E32.1 Abscess of thymus	0.003	0.997	0.000
E32.0 Persistent hyperplasia of thymus	0.003	0.997	0.000
S51.7 Multiple open wounds of forearm	0.003	0.997	0.000
S05.8 Other injuries of eye and orbit	0.003	0.997	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.003	0.997	0.000
V89.2 Person injured in unspecified motor-vehicle accident, traffic	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
E22.0 Acromegaly and pituitary gigantism	0.003	0.997	0.000
E25.9 Adrenogenital disorder, unspecified	0.003	0.997	0.000
E25.8 Other adrenogenital disorders	0.003	0.997	0.000
E30.9 Disorder of puberty, unspecified	0.003	0.997	0.000
E30.8 Other disorders of puberty	0.003	0.997	0.000
E30.1 Precocious puberty	0.003	0.997	0.000
E30.0 Delayed puberty	0.003	0.997	0.000
E31.9 Polyglandular dysfunction, unspecified	0.003	0.997	0.000
E31.8 Other polyglandular dysfunction	0.003	0.997	0.000
E31.1 Polyglandular hyperfunction	0.003	0.997	0.000
E31.0 Autoimmune polyglandular failure	0.003	0.997	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.003	0.997	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.003	0.997	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.003	0.997	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.003	0.997	0.000
M10.98 Gout, unspecified (Other)	0.000	0.997	0.003
M10.95 Gout, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
M10.91 Gout, unspecified (Shoulder region)	0.000	0.997	0.003
E24 Cushing's syndrome	0.003	0.997	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.003	0.997	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.000	0.997	0.003
D23.4 Skin of scalp and neck	0.000	0.997	0.003
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.997	0.000
E23.7 Disorder of pituitary gland, unspecified	0.003	0.997	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.003	0.997	0.000
S51 Open wound of forearm	0.003	0.997	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.997	0.003
E22.9 Hyperfunction of pituitary gland, unspecified	0.003	0.997	0.000
E22.8 Other hyperfunction of pituitary gland	0.003	0.997	0.000
E23.6 Other disorders of pituitary gland	0.003	0.997	0.000
M89.8 Other specified disorders of bone	0.000	0.997	0.003
E26.8 Other hyperaldosteronism	0.003	0.997	0.000
E26.1 Secondary hyperaldosteronism	0.003	0.997	0.000
E29 Testicular dysfunction	0.002	0.997	0.000
M81 Osteoporosis without pathological fracture	0.003	0.997	0.000
E21.0 Primary hyperparathyroidism	0.003	0.997	0.000
K76.6 Portal hypertension	0.000	0.997	0.003
D23.5 Skin of trunk	0.000	0.997	0.003
E20.8 Other hypoparathyroidism	0.002	0.997	0.000
E20.1 Pseudohypoparathyroidism	0.002	0.997	0.000
E20.0 Idiopathic hypoparathyroidism	0.002	0.997	0.000
J69 Pneumonitis due to solids and liquids	0.003	0.997	0.000
E26.0 Primary hyperaldosteronism	0.003	0.997	0.000
H53.9 Visual disturbance, unspecified	0.000	0.997	0.003
E26.9 Hyperaldosteronism, unspecified	0.002	0.997	0.000
S51.8 Open wound of other parts of forearm	0.003	0.997	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.003	0.997	0.000
M10.93 Gout, unspecified (Forearm)	0.000	0.997	0.002
M19.93 Arthrosis, unspecified (Forearm)	0.003	0.997	0.000
D23.9 Skin, unspecified	0.000	0.997	0.003
H02.4 Ptosis of eyelid	0.000	0.997	0.003
M48.06 Spinal stenosis (Lumbar region)	0.000	0.997	0.003
R40.2 Coma, unspecified	0.000	0.997	0.003
D37.1 Stomach	0.000	0.997	0.003
E28.3 Primary ovarian failure	0.002	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.998	0.002
M89.83 Other specified disorders of bone (Forearm)	0.000	0.998	0.002
M10.92 Gout, unspecified (Upper arm)	0.000	0.998	0.002
I49.1 Atrial premature depolarisation	0.000	0.998	0.002
K91.0 Vomiting following gastro-intestinal surgery	0.002	0.998	0.000
D23.0 Skin of lip	0.000	0.998	0.002
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.002	0.998	0.000
E24.3 Ectopic ACTH syndrome	0.002	0.998	0.000
E24.1 Nelson's syndrome	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.998	0.002
H11.1 Conjunctival degenerations and deposits	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.000	0.998	0.002
K91.3 Postoperative intestinal obstruction	0.002	0.998	0.000
M48.09 Spinal stenosis (Site unspecified)	0.000	0.998	0.002
K56.2 Volvulus	0.002	0.998	0.000
E24.0 Pituitary-dependent Cushing's disease	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.998	0.002
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
E29.9 Testicular dysfunction, unspecified	0.002	0.998	0.000
E29.8 Other testicular dysfunction	0.002	0.998	0.000
E29.0 Testicular hyperfunction	0.002	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.998	0.002
M81.8 Other osteoporosis	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
Z60 Problems related to social environment	0.002	0.998	0.000
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.002	0.998	0.000
L03.0 Cellulitis of finger and toe	0.002	0.998	0.000
E24.8 Other Cushing's syndrome	0.002	0.998	0.000
I86.1 Scrotal varices	0.002	0.998	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.002	0.998	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
G04.0 Acute disseminated encephalitis	0.002	0.998	0.000
J69.1 Pneumonitis due to oils and essences	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.002	0.998	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.998	0.002
D23.2 Skin of ear and external auricular canal	0.000	0.998	0.002
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.002	0.998	0.000
G04.1 Tropical spastic paraplegia	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.002	0.998	0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.998	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.002
Z60.8 Other problems related to social environment	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
M89.3 Hypertrophy of bone	0.000	0.998	0.002
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.998	0.002
M48.0 Spinal stenosis	0.000	0.998	0.002
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.000	0.998	0.002
E24.9 Cushing's syndrome, unspecified	0.002	0.998	0.000
O00.1 Tubal pregnancy	0.000	0.998	0.002
B25.9 Cytomegaloviral disease, unspecified	0.000	0.998	0.002
S50.1 Contusion of other and unspecified parts of forearm	0.002	0.998	0.000
J69.8 Pneumonitis due to other solids and liquids	0.002	0.998	0.000
M49.5 Collapsed vertebra in diseases classified elsewhere	0.000	0.998	0.002
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.998	0.000
M89.5 Osteolysis	0.000	0.998	0.002
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)	0.000	0.998	0.002
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.998	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.998	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.998	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.998	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.998	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.998	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.998	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.998	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.998	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.998	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.998	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.998	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.998	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.998	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.998	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.998	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.998	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.998	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.998	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.998	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.998	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.88 Other osteoporosis (Other)	0.002	0.998	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.998	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.998	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.998	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.998	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.998	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.998	0.000
Z60.5 Target of perceived adverse discrimination and persecution	0.002	0.998	0.000
Z60.4 Social exclusion and rejection	0.002	0.998	0.000
Z60.3 Acculturation difficulty	0.002	0.998	0.000
Z60.1 Atypical parenting situation	0.002	0.998	0.000
Z60.0 Problems of adjustment to life-cycle transitions	0.002	0.998	0.000
S51.0 Open wound of elbow	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.002	0.998	0.000
M81.29 Osteoporosis of disuse (Site unspecified)	0.002	0.998	0.000
M81.28 Osteoporosis of disuse (Other)	0.002	0.998	0.000
M81.27 Osteoporosis of disuse (Ankle and foot)	0.002	0.998	0.000
M81.26 Osteoporosis of disuse (Lower leg)	0.002	0.998	0.000
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.002	0.998	0.000
M81.24 Osteoporosis of disuse (Hand)	0.002	0.998	0.000
M81.23 Osteoporosis of disuse (Forearm)	0.002	0.998	0.000
M81.22 Osteoporosis of disuse (Upper arm)	0.002	0.998	0.000
M81.21 Osteoporosis of disuse (Shoulder region)	0.002	0.998	0.000
R59.1 Generalised enlarged lymph nodes	0.000	0.998	0.002
M89 Other disorders of bone	0.000	0.998	0.002
O61 Failed induction of labour	0.002	0.998	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.002	0.998	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.002	0.998	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.002	0.998	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.002	0.998	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.002	0.998	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.002	0.998	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.002	0.998	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.002	0.998	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.998	0.002
M22.4 Chondromalacia patellae	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
N94.6 Dysmenorrhoea, unspecified	0.002	0.998	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)	0.000	0.998	0.002
M81.08 Postmenopausal osteoporosis (Other)	0.001	0.998	0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.06 Postmenopausal osteoporosis (Lower leg)	0.001	0.998	0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.04 Postmenopausal osteoporosis (Hand)	0.001	0.998	0.000
M81.03 Postmenopausal osteoporosis (Forearm)	0.001	0.998	0.000
M81.02 Postmenopausal osteoporosis (Upper arm)	0.001	0.998	0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.001	0.998	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.001	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.002
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.002
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.002
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.002
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.002
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.002
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.002
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.002
N39.8 Other specified disorders of urinary system	0.000	0.998	0.002
M48.03 Spinal stenosis (Cervicothoracic region)	0.000	0.998	0.002
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
W11.6 Industrial and construction area	0.000	0.998	0.002
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.998	0.001
M54.2 Cervicalgia	0.000	0.998	0.002
O61.1 Failed instrumental induction of labour	0.002	0.998	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.002	0.998	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.000	0.998	0.002
W00.3 Sports and athletics area	0.002	0.998	0.000
Z44.3 Fitting and adjustment of external breast prosthesis	0.002	0.998	0.000
Z60.9 Problem related to social environment, unspecified	0.002	0.998	0.000
M48.04 Spinal stenosis (Thoracic region)	0.000	0.998	0.002
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)	0.000	0.998	0.002
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)	0.000	0.998	0.002
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)	0.000	0.998	0.002
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)	0.000	0.998	0.002
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)	0.000	0.998	0.002
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)	0.000	0.998	0.002
C26.0 Intestinal tract, part unspecified	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.000	0.998	0.001
M89.58 Osteolysis (Other)	0.000	0.998	0.001
M89.57 Osteolysis (Ankle and foot)	0.000	0.998	0.001
M89.56 Osteolysis (Lower leg)	0.000	0.998	0.001
M89.54 Osteolysis (Hand)	0.000	0.998	0.001
M89.53 Osteolysis (Forearm)	0.000	0.998	0.001
M89.52 Osteolysis (Upper arm)	0.000	0.998	0.001
M89.51 Osteolysis (Shoulder region)	0.000	0.998	0.001
M89.50 Osteolysis (Multiple sites)	0.000	0.998	0.001
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.998	0.002
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.001	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.002	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.002	0.998	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.998	0.002
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.002	0.998	0.000
Z48.8 Other specified surgical follow-up care	0.000	0.998	0.002
F42.9 Obsessive-compulsive disorder, unspecified	0.000	0.998	0.002
W14.9 Unspecified place	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
M81.48 Drug-induced osteoporosis (Other)	0.001	0.998	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.998	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.998	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.998	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.998	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.998	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.001	0.998	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.001	0.998	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.002	0.998	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.998	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.001	0.998	0.000
H00.1 Chalazion	0.002	0.998	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.002	0.998	0.000
M89.6 Osteopathy after poliomyelitis	0.000	0.998	0.001
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.001
M89.2 Other disorders of bone development and growth	0.000	0.998	0.001
M89.1 Epiphyseal arrest	0.000	0.998	0.001
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.002	0.998	0.000
S50 Superficial injury of forearm	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.001	0.998	0.000
O61.8 Other failed induction of labour	0.001	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.001	0.998	0.000
K70.0 Alcoholic fatty liver	0.000	0.998	0.002
M45 Ankylosing spondylitis	0.000	0.998	0.002
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified	0.000	0.998	0.002
K91.1 Postgastric surgery syndromes	0.001	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.000	0.998	0.002
B18 Chronic viral hepatitis	0.000	0.998	0.002
M48 Other spondylopathies	0.000	0.998	0.002
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.998	0.001
O61.9 Failed induction of labour, unspecified	0.001	0.998	0.000
M49 Spondylopathies in diseases classified elsewhere	0.000	0.998	0.001
M54.27 Cervicalgia-Lumbosacral	0.000	0.998	0.001
M54.26 Cervicalgia-Lumbar	0.000	0.998	0.001
M54.25 Cervicalgia-Thoracolumbar	0.000	0.998	0.001
M54.24 Cervicalgia-Thoracic	0.000	0.998	0.001
M54.20 Cervicalgia-Mult site	0.000	0.998	0.001
N63 Unspecified lump in breast	0.000	0.998	0.002
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.998	0.001
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.998	0.001
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.998	0.001
I27 Other pulmonary heart diseases	0.000	0.999	0.001
K76.7 Hepatorenal syndrome	0.000	0.999	0.001
M48.07 Spinal stenosis (Lumbosacral region)	0.000	0.999	0.001
I27.8 Other specified pulmonary heart diseases	0.000	0.999	0.001
K91.5 Postcholecystectomy syndrome	0.001	0.999	0.000
K91.4 Colostomy and enterostomy malfunction	0.001	0.999	0.000
M10 Gout	0.000	0.999	0.001
M40.24 Other and unspecified kyphosis (Thoracic region)	0.001	0.999	0.000
E29.1 Testicular hypofunction	0.001	0.999	0.001
G25.0 Essential tremor	0.001	0.999	0.000
I79.1 Aortitis in diseases classified elsewhere	0.001	0.999	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.001	0.999	0.000
K76.9 Liver disease, unspecified	0.000	0.999	0.001
S50.0 Contusion of elbow	0.001	0.999	0.000
M46.46 Discitis, unspecified (Lumbar region)	0.000	0.999	0.001
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.999	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.000	0.999	0.001
M89.18 Epiphyseal arrest (Other)	0.000	0.999	0.001
M89.17 Epiphyseal arrest (Ankle and foot)	0.000	0.999	0.001
M89.16 Epiphyseal arrest (Lower leg)	0.000	0.999	0.001
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.000	0.999	0.001
M89.14 Epiphyseal arrest (Hand)	0.000	0.999	0.001
M89.13 Epiphyseal arrest (Forearm)	0.000	0.999	0.001
M89.12 Epiphyseal arrest (Upper arm)	0.000	0.999	0.001
M89.11 Epiphyseal arrest (Shoulder region)	0.000	0.999	0.001
M89.10 Epiphyseal arrest (Multiple sites)	0.000	0.999	0.001
M89.29 Other disorders of bone development and growth (Site unspecified)	0.000	0.999	0.001
M89.28 Other disorders of bone development and growth (Other)	0.000	0.999	0.001
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.000	0.999	0.001
M89.26 Other disorders of bone development and growth (Lower leg)	0.000	0.999	0.001
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.000	0.999	0.001
M89.24 Other disorders of bone development and growth (Hand)	0.000	0.999	0.001
M89.23 Other disorders of bone development and growth (Forearm)	0.000	0.999	0.001
M89.22 Other disorders of bone development and growth (Upper arm)	0.000	0.999	0.001
M89.21 Other disorders of bone development and growth (Shoulder region)	0.000	0.999	0.001
M89.20 Other disorders of bone development and growth (Multiple sites)	0.000	0.999	0.001
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.000	0.999	0.001
M89.48 Other hypertrophic osteoarthropathy (Other)	0.000	0.999	0.001
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.000	0.999	0.001
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.000	0.999	0.001
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.000	0.999	0.001
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.000	0.999	0.001
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.000	0.999	0.001
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.000	0.999	0.001
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.000	0.999	0.001
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.000	0.999	0.001
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.000	0.999	0.001
M89.68 Osteopathy after poliomyelitis (Other)	0.000	0.999	0.001
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.000	0.999	0.001
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.000	0.999	0.001
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.000	0.999	0.001
M89.64 Osteopathy after poliomyelitis (Hand)	0.000	0.999	0.001
M89.63 Osteopathy after poliomyelitis (Forearm)	0.000	0.999	0.001
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.000	0.999	0.001
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.000	0.999	0.001
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.000	0.999	0.001
I89.1 Lymphangitis	0.000	0.999	0.001
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.999	0.001
S50.7 Multiple superficial injuries of forearm	0.001	0.999	0.000
M23.49 Loose body in knee-Unspec lig/men	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
B18.9 Chronic viral hepatitis, unspecified	0.000	0.999	0.001
B18.8 Other chronic viral hepatitis	0.000	0.999	0.001
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.999	0.001
I27.0 Primary pulmonary hypertension	0.000	0.999	0.001
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.999	0.001
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.999	0.001
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.999	0.001
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.999	0.001
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.999	0.001
V89.3 Person injured in unspecified nonmotor-vehicle accident, traffic	0.000	0.999	0.001
V89.1 Person injured in unspecified nonmotor-vehicle accident, nontraffic	0.000	0.999	0.001
V89.0 Person injured in unspecified motor-vehicle accident, nontraffic	0.000	0.999	0.001
M46.44 Discitis, unspecified (Thoracic region)	0.000	0.999	0.001
D03.3 Melanoma in situ of other and unspecified parts of face	0.000	0.999	0.001
M48.4 Fatigue fracture of vertebra	0.000	0.999	0.001
M48.3 Traumatic spondylopathy	0.000	0.999	0.001
M48.2 Kissing spine	0.000	0.999	0.001
M48.1 Ankylosing hyperostosis [Forestier]	0.000	0.999	0.001
M49.8 Spondylopathy in other diseases classified elsewhere	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations