TreeWAS – Variant ID: rs10995439

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z80.3 Family history of malignant neoplasm of breast	0.000	0.954	0.046
Z80 Family history of malignant neoplasm	0.000	0.957	0.043
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.000	0.959	0.041
Z80.4 Family history of malignant neoplasm of genital organs	0.000	0.960	0.040
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.000	0.960	0.040
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.962	0.038
Z80.6 Family history of leukaemia	0.000	0.967	0.032
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.000	0.968	0.032
O32.1 Maternal care for breech presentation	0.027	0.973	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.973	0.027
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.981	0.018
O32 Maternal care for known or suspected malpresentation of foetus	0.017	0.983	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.016	0.984	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.016	0.984	0.000
O32.2 Maternal care for transverse and oblique lie	0.014	0.986	0.000
S92.00 Fracture of calcaneus (closed)	0.014	0.986	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.987	0.013
O32.3 Maternal care for face, brow and chin presentation	0.012	0.988	0.000
O32.6 Maternal care for compound presentation	0.012	0.988	0.000
V23.4 Driver injured in traffic accident	0.000	0.988	0.012
O32.4 Maternal care for high head at term	0.011	0.989	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.009	0.991	0.000
Z89.5 Acquired absence of leg at or below knee	0.000	0.991	0.009
S92.0 Fracture of calcaneus	0.008	0.991	0.000
M17.0 Primary gonarthrosis, bilateral	0.008	0.992	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.008	0.992	0.000
H02.3 Blepharochalasis	0.008	0.992	0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.000	0.992	0.008
O34.8 Maternal care for other abnormalities of pelvic organs	0.007	0.993	0.000
E27 Other disorders of adrenal gland	0.000	0.993	0.007
O32.0 Maternal care for unstable lie	0.007	0.993	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.993	0.007
O34.7 Maternal care for abnormality of vulva and perineum	0.007	0.993	0.000
O34.1 Maternal care for tumour of corpus uteri	0.007	0.993	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.007	0.993	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.993	0.007
E27.2 Addisonian crisis	0.000	0.993	0.007
O34.3 Maternal care for cervical incompetence	0.007	0.993	0.000
O34.4 Maternal care for other abnormalities of cervix	0.007	0.993	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.993	0.007
F31 Bipolar affective disorder	0.007	0.993	0.000
O34.0 Maternal care for congenital malformation of uterus	0.006	0.994	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.006	0.994	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.994	0.006
Z89 Acquired absence of limb	0.000	0.994	0.006
E87.6 Hypokalaemia	0.000	0.994	0.006
O34.6 Maternal care for abnormality of vagina	0.006	0.994	0.000
M23.49 Loose body in knee-Unspec lig/men	0.006	0.994	0.000
F31.7 Bipolar affective disorder, currently in remission	0.006	0.994	0.000
V23.5 Passenger injured in traffic accident	0.000	0.994	0.006
O34.5 Maternal care for other abnormalities of gravid uterus	0.006	0.994	0.000
S92.01 Fracture of calcaneus (open)	0.006	0.994	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.994	0.006
V23.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.994	0.006
V23.3 Person injured while boarding or alighting	0.000	0.994	0.006
V23.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.994	0.006
V23.1 Passenger injured in nontraffic accident	0.000	0.994	0.006
Z89.0 Acquired absence of finger(s) [including thumb], unilateral	0.000	0.994	0.006
O32.8 Maternal care for other malpresentation of foetus	0.005	0.994	0.001
E27.5 Adrenomedullary hyperfunction	0.000	0.994	0.005
E27.0 Other adrenocortical overactivity	0.000	0.994	0.005
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.006	0.994	0.000
V23.0 Driver injured in nontraffic accident	0.000	0.994	0.005
F31.6 Bipolar affective disorder, current episode mixed	0.005	0.995	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.995	0.005
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.005	0.995	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.995	0.005
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.005	0.995	0.000
I51.9 Heart disease, unspecified	0.000	0.995	0.005
Z89.9 Acquired absence of limb, unspecified	0.000	0.995	0.005
F31.8 Other bipolar affective disorders	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.995	0.005
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.995	0.005
Z89.3 Acquired absence of both upper limbs [any level]	0.000	0.995	0.005
Z89.1 Acquired absence of hand and wrist	0.000	0.995	0.005
S92 Fracture of foot, except ankle	0.005	0.995	0.000
Z89.7 Acquired absence of both lower limbs [any level, except toes alone]	0.000	0.995	0.005
Z89.6 Acquired absence of leg above knee	0.000	0.995	0.005
F31.9 Bipolar affective disorder, unspecified	0.005	0.995	0.000
V20-V29 Motorcycle rider injured in transport accident	0.000	0.995	0.005
H57.9 Disorder of eye and adnexa, unspecified	0.005	0.995	0.000
D22.6 Melanocytic naevi of upper limb, including shoulder	0.005	0.995	0.000
V23.99 Motorcycle rider injured in collision with car, pick-up truck or van, Unspecified motorcycle rider injured in traffic accident, Unspecified place	0.000	0.996	0.004
Z89.8 Acquired absence of upper and lower limbs [any level]	0.000	0.996	0.004
E06.3 Autoimmune thyroiditis	0.000	0.996	0.004
N76.8 Other specified inflammation of vagina and vulva	0.000	0.996	0.004
S92.4 Fracture of great toe	0.004	0.996	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.004	0.996	0.000
Z89.2 Acquired absence of upper limb above wrist	0.000	0.996	0.004
T80.6 Other serum reactions	0.000	0.996	0.004
T80.5 Anaphylactic shock due to serum	0.000	0.996	0.004
T80.4 Rh incompatibility reaction	0.000	0.996	0.004
T80.3 ABO incompatibility reaction	0.000	0.996	0.004
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.996	0.004
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.004	0.996	0.000
V28 Motorcycle rider injured in noncollision transport accident	0.000	0.996	0.004
C44.9 Malignant neoplasm of skin, unspecified	0.004	0.996	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.000	0.996	0.004
S92.40 Fracture of great toe (closed)	0.004	0.996	0.000
S92.9 Fracture of foot, unspecified	0.004	0.996	0.000
U80.0 Penicillin resistant agent	0.000	0.996	0.004
S92.5 Fracture of other toe	0.004	0.996	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.996	0.004
V29 Motorcycle rider injured in other and unspecified transport accidents	0.000	0.996	0.004
V27 Motorcycle rider injured in collision with fixed or stationary object	0.000	0.996	0.004
F31.0 Bipolar affective disorder, current episode hypomanic	0.004	0.996	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.996	0.004
V28.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.996	0.004
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle	0.000	0.996	0.003
N72 Inflammatory disease of cervix uteri	0.000	0.996	0.004
V26 Motorcycle rider injured in collision with other nonmotor vehicle	0.000	0.996	0.003
V25 Motorcycle rider injured in collision with railway train or railway vehicle	0.000	0.996	0.003
V21 Motorcycle rider injured in collision with pedal cycle	0.000	0.996	0.003
S92.1 Fracture of talus	0.003	0.996	0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus	0.000	0.996	0.003
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.997	0.003
E34.0 Carcinoid syndrome	0.000	0.997	0.003
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.000	0.997	0.003
M23.4 Loose body in knee	0.003	0.997	0.000
U80.1 Methicillin resistant agent	0.000	0.997	0.003
V20 Motorcycle rider injured in collision with pedestrian or animal	0.000	0.997	0.003
S92.41 Fracture of great toe (open)	0.003	0.997	0.000
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
I73.0 Raynaud's syndrome	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.000	0.997	0.003
M23.44 Loose body in knee-Lat lig/ant men	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
V28.5 Passenger injured in traffic accident	0.000	0.997	0.003
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.997	0.003
V29.3 Motorcycle rider [any] injured in unspecified nontraffic accident	0.000	0.997	0.003
V28.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
S92.90 Fracture of foot, unspecified (closed)	0.003	0.997	0.000
V28.4 Driver injured in traffic accident	0.000	0.997	0.003
V28.0 Driver injured in nontraffic accident	0.000	0.997	0.003
V28.3 Person injured while boarding or alighting	0.000	0.997	0.003
V28.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
V27.4 Driver injured in traffic accident	0.000	0.997	0.003
Y79.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
E34 Other endocrine disorders	0.000	0.997	0.003
S92.91 Fracture of foot, unspecified (open)	0.003	0.997	0.000
S92.11 Fracture of talus (open)	0.003	0.997	0.000
V29.9 Motorcycle rider [any] injured in unspecified traffic accident	0.000	0.997	0.003
V29.8 Motorcycle rider [any] injured in other specified transport accidents	0.000	0.997	0.003
V29.6 Unspecified motorcycle rider injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.997	0.003
V29.5 Passenger injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.997	0.003
V29.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.000	0.997	0.003
V29.2 Unspecified motorcycle rider injured in collision with other and unspecified motor vehicles in nontraffic accident	0.000	0.997	0.003
V29.1 Passenger injured in collision with other and unspecified motor vehicles in nontraffic accident	0.000	0.997	0.003
V29.0 Driver injured in collision with other and unspecified motor vehicles in nontraffic accident	0.000	0.997	0.003
V27.0 Driver injured in nontraffic accident	0.000	0.997	0.003
V27.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
V27.5 Passenger injured in traffic accident	0.000	0.997	0.003
V27.3 Person injured while boarding or alighting	0.000	0.997	0.003
V27.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.003
V27.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
S90 Superficial injury of ankle and foot	0.003	0.997	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.003	0.997	0.000
S13.4 Sprain and strain of cervical spine	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
M23.40 Loose body in knee-Mult sites	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.000	0.997	0.003
E34.9 Endocrine disorder, unspecified	0.000	0.997	0.003
M62.8 Other specified disorders of muscle	0.000	0.997	0.003
S90.8 Other superficial injuries of ankle and foot	0.003	0.997	0.000
V22.4 Driver injured in traffic accident	0.000	0.997	0.003
V22.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
V22.5 Passenger injured in traffic accident	0.000	0.997	0.003
V22.3 Person injured while boarding or alighting	0.000	0.997	0.003
V22.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.003
V22.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
V22.0 Driver injured in nontraffic accident	0.000	0.997	0.003
E20-E35 Disorders of other endocrine glands	0.000	0.997	0.003
U51.1 Previously admitted to a psychiatric hospital of the provider	0.003	0.997	0.000
V21.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
V21.5 Passenger injured in traffic accident	0.000	0.997	0.003
V21.4 Driver injured in traffic accident	0.000	0.997	0.003
V21.3 Person injured while boarding or alighting	0.000	0.997	0.003
V21.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.003
V21.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
V21.0 Driver injured in nontraffic accident	0.000	0.997	0.003
V24.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
V24.5 Passenger injured in traffic accident	0.000	0.997	0.003
V24.3 Person injured while boarding or alighting	0.000	0.997	0.003
V24.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.003
V24.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
V24.0 Driver injured in nontraffic accident	0.000	0.997	0.003
V25.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
V25.5 Passenger injured in traffic accident	0.000	0.997	0.003
V25.4 Driver injured in traffic accident	0.000	0.997	0.003
V25.3 Person injured while boarding or alighting	0.000	0.997	0.003
V25.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.003
V25.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
V25.0 Driver injured in nontraffic accident	0.000	0.997	0.003
V26.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.003
V26.5 Passenger injured in traffic accident	0.000	0.997	0.003
V26.4 Driver injured in traffic accident	0.000	0.997	0.003
V26.3 Person injured while boarding or alighting	0.000	0.997	0.003
V26.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.003
V26.1 Passenger injured in nontraffic accident	0.000	0.997	0.003
V26.0 Driver injured in nontraffic accident	0.000	0.997	0.003
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.003	0.997	0.000
S63.6 Sprain and strain of finger(s)	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
V24.4 Driver injured in traffic accident	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
I51.4 Myocarditis, unspecified	0.000	0.997	0.003
S92.50 Fracture of other toe (closed)	0.003	0.997	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.000	0.997	0.003
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
M23.47 Loose body in knee-Capsular lig	0.003	0.997	0.000
M23.45 Loose body in knee-Pst hrn lat men	0.003	0.997	0.000
M23.42 Loose body in knee-Pst lig/hrn men	0.003	0.997	0.000
I51.7 Cardiomegaly	0.000	0.997	0.003
S12.2 Fracture of other specified cervical vertebra	0.003	0.997	0.000
V20.9 Unspecified motorcycle rider injured in traffic accident	0.000	0.997	0.002
V20.5 Passenger injured in traffic accident	0.000	0.997	0.002
V20.3 Person injured while boarding or alighting	0.000	0.997	0.002
V20.2 Unspecified motorcycle rider injured in nontraffic accident	0.000	0.997	0.002
V20.1 Passenger injured in nontraffic accident	0.000	0.997	0.002
V20.0 Driver injured in nontraffic accident	0.000	0.997	0.002
E26 Hyperaldosteronism	0.000	0.997	0.003
S12 Fracture of neck	0.003	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.997	0.000
E26.0 Primary hyperaldosteronism	0.000	0.997	0.003
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.997	0.003
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.997	0.003
I51.0 Cardiac septal defect, acquired	0.000	0.997	0.003
M62.81 Other specified disorders of muscle (Shoulder region)	0.000	0.997	0.003
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.997	0.003
I51 Complications and ill-defined descriptions of heart disease	0.000	0.997	0.003
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.997	0.003
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.997	0.000
S13.1 Dislocation of cervical vertebra	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.002	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.000	0.997	0.003
R07.1 Chest pain on breathing	0.000	0.997	0.003
M23.41 Loose body in knee-Ant lig/hrn men	0.002	0.997	0.000
S19.9 Unspecified injury of neck	0.003	0.997	0.000
V28.09 Motorcycle rider injured in noncollision transport accident; driver injured in nontraffic accident; during unspecified activity	0.000	0.997	0.002
V28.49 Motorcycle rider injured in noncollision transport accident; driver injured in traffic accident; during unspecified activity	0.000	0.997	0.002
S12.0 Fracture of first cervical vertebra	0.002	0.997	0.000
T87.6 Other and unspecified complications of amputation stump	0.000	0.997	0.003
E29 Testicular dysfunction	0.000	0.997	0.003
Y79 Orthopaedic devices associated with adverse incidents	0.003	0.997	0.000
G82.5 Tetraplegia, unspecified	0.003	0.997	0.000
M11.2 Other chondrocalcinosis	0.002	0.997	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.002	0.997	0.000
E34.5 Androgen resistance syndrome	0.000	0.997	0.002
E34.4 Constitutional tall stature	0.000	0.997	0.002
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.997	0.002
E34.1 Other hypersecretion of intestinal hormones	0.000	0.997	0.002
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.002	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.002	0.997	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.997	0.003
E31 Polyglandular dysfunction	0.000	0.997	0.002
V20.4 Driver injured in traffic accident	0.000	0.997	0.002
S96 Injury of muscle and tendon at ankle and foot level	0.002	0.997	0.000
D89.1 Cryoglobulinaemia	0.000	0.997	0.002
E34.3 Short stature, not elsewhere classified	0.000	0.997	0.002
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.997	0.002
S99 Other and unspecified injuries of ankle and foot	0.002	0.997	0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
M23.43 Loose body in knee-Med lig/oth men	0.002	0.998	0.000
M62.84 Other specified disorders of muscle (Hand)	0.000	0.998	0.002
V29.69 Unspecified motorcycle rider injured in collision with other and unspecified motor vehicles in traffic accident; during unspecified activity	0.000	0.998	0.002
V29.80 Motorcycle rider [any] injured in other specified transport accidents; while engaged in sports activity	0.000	0.998	0.002
V29.99 Motorcycle rider [any] injured in unspecified traffic accident; during unspecified activity	0.000	0.998	0.002
Y79.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
E24 Cushing's syndrome	0.000	0.998	0.002
V27.09 Motorcycle rider injured in collision with fixed or stationary object; driver injured in nontraffic accident; during unspecified activity	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S19 Other and unspecified injuries of neck	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.998	0.002
S98 Traumatic amputation of ankle and foot	0.002	0.998	0.000
S95 Injury of blood vessels at ankle and foot level	0.002	0.998	0.000
S94 Injury of nerves at ankle and foot level	0.002	0.998	0.000
S10-S19 Injuries to the neck	0.002	0.998	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.002	0.998	0.000
S13.5 Sprain and strain of thyroid region	0.002	0.998	0.000
S13.3 Multiple dislocations of neck	0.002	0.998	0.000
S13.2 Dislocation of other and unspecified parts of neck	0.002	0.998	0.000
S13.0 Traumatic rupture of cervical intervertebral disk	0.002	0.998	0.000
S63.0 Dislocation of wrist	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E32 Diseases of thymus	0.000	0.998	0.002
E30 Disorders of puberty, not elsewhere classified	0.000	0.998	0.002
M62.65 Muscle strain (Pelvic region and thigh)	0.000	0.998	0.002
E29.9 Testicular dysfunction, unspecified	0.000	0.998	0.002
E31.0 Autoimmune polyglandular failure	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
E20 Hypoparathyroidism	0.000	0.998	0.002
M23.46 Loose body in knee-O/unsp lat men	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.998	0.002
S92.70 Multiple fractures of foot (closed)	0.002	0.998	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.000	0.998	0.002
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
M62.83 Other specified disorders of muscle (Forearm)	0.000	0.998	0.002
E26.8 Other hyperaldosteronism	0.000	0.998	0.002
E26.1 Secondary hyperaldosteronism	0.000	0.998	0.002
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.998	0.002
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.002
D83 Common variable immunodeficiency	0.000	0.998	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.998	0.002
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
E25 Adrenogenital disorders	0.000	0.998	0.002
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.998	0.002
U51 Admission status on psychiatric patients	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.998	0.002
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.998	0.002
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.998	0.002
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.998	0.002
E34.8 Other specified endocrine disorders	0.000	0.998	0.002
H52.2 Astigmatism	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
S12.01 Fracture of first cervical vertebra (open)	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.998	0.002
E26.9 Hyperaldosteronism, unspecified	0.000	0.998	0.002
E29.8 Other testicular dysfunction	0.000	0.998	0.002
E29.1 Testicular hypofunction	0.000	0.998	0.002
E29.0 Testicular hyperfunction	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y79.0 Diagnostic and monitoring devices	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.002	0.998	0.000
M11.28 Other chondrocalcinosis (Other)	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.002	0.998	0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.002	0.998	0.000
M11.24 Other chondrocalcinosis (Hand)	0.002	0.998	0.000
M11.23 Other chondrocalcinosis (Forearm)	0.002	0.998	0.000
M11.22 Other chondrocalcinosis (Upper arm)	0.002	0.998	0.000
M11.20 Other chondrocalcinosis (Multiple sites)	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.000	0.998	0.002
E31.9 Polyglandular dysfunction, unspecified	0.000	0.998	0.002
E31.8 Other polyglandular dysfunction	0.000	0.998	0.002
E31.1 Polyglandular hyperfunction	0.000	0.998	0.002
S63.5 Sprain and strain of wrist	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.000	0.998	0.002
E24.8 Other Cushing's syndrome	0.000	0.998	0.002
H52.1 Myopia	0.002	0.998	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.998	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.998	0.002
E24.3 Ectopic ACTH syndrome	0.000	0.998	0.002
E24.1 Nelson's syndrome	0.000	0.998	0.002
S97 Crushing injury of ankle and foot	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.002	0.998	0.000
E24.2 Drug-induced Cushing's syndrome	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.000	0.998	0.002
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.002	0.998	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
D07.1 Vulva	0.000	0.998	0.002
S19.8 Other specified injuries of neck	0.002	0.998	0.000
S63.1 Dislocation finger	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
E30.9 Disorder of puberty, unspecified	0.000	0.998	0.002
E30.8 Other disorders of puberty	0.000	0.998	0.002
E30.1 Precocious puberty	0.000	0.998	0.002
E30.0 Delayed puberty	0.000	0.998	0.002
E32.9 Disease of thymus, unspecified	0.000	0.998	0.002
E32.8 Other diseases of thymus	0.000	0.998	0.002
E32.1 Abscess of thymus	0.000	0.998	0.002
E32.0 Persistent hyperplasia of thymus	0.000	0.998	0.002
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.998	0.002
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.998	0.002
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.998	0.002
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
E20.8 Other hypoparathyroidism	0.000	0.998	0.002
E20.1 Pseudohypoparathyroidism	0.000	0.998	0.002
E20.0 Idiopathic hypoparathyroidism	0.000	0.998	0.002
J06.9 Acute upper respiratory infection, unspecified	0.000	0.998	0.002
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
M62.6 Muscle strain	0.000	0.998	0.002
S14.6 Injury of other and unspecified nerves of neck	0.002	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.002	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.002	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.002	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
D81 Combined immunodeficiencies	0.000	0.998	0.002
E20.9 Hypoparathyroidism, unspecified	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
U51.2 Previously admitted to a psychiatric hospital of another provider	0.002	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
S12.81 Fracture of other parts of neck (open)	0.002	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.002
E24.0 Pituitary-dependent Cushing's disease	0.000	0.998	0.002
G95.9 Disease of spinal cord, unspecified	0.002	0.998	0.000
S63.2 Multiple dislocations of fingers	0.002	0.998	0.000
U51.0 Not Previously admitted to a psyciatric hospital	0.002	0.998	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.998	0.002
S10 Superficial injury of neck	0.002	0.998	0.000
E25.9 Adrenogenital disorder, unspecified	0.000	0.998	0.002
E25.8 Other adrenogenital disorders	0.000	0.998	0.002
N05.8 Other	0.002	0.998	0.000
M62 Other disorders of muscle	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.998	0.002
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
D86 Sarcoidosis	0.000	0.998	0.002
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.000	0.998	0.001
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.000	0.998	0.002
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.000	0.998	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.000	0.998	0.002
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
E28 Ovarian dysfunction	0.000	0.998	0.002
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified	0.002	0.998	0.000
T87.3 Neuroma of amputation stump	0.000	0.998	0.002
Z50.1 Other physical therapy	0.000	0.998	0.002
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
N64.1 Fat necrosis of breast	0.002	0.998	0.000
Q63.0 Accessory kidney	0.002	0.998	0.000
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.001	0.998	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.002	0.998	0.000
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.998	0.002
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.998	0.002
S63.11 Subluxation and dislocation of metacarpophalangeal joint of thumb	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations