TreeWAS – Variant ID: rs11006253

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H66 Suppurative and unspecified otitis media	0.506	0.494	0.000
H66.9 Otitis media, unspecified	0.505	0.495	0.000
H65-H75 Diseases of middle ear and mastoid	0.500	0.500	0.000
H72 Perforation of tympanic membrane	0.486	0.514	0.000
Chapter VIII Diseases of the ear and mastoid process	0.479	0.521	0.000
H90-H95 Other disorders of ear	0.465	0.535	0.000
H60-H62 Diseases of external ear	0.461	0.539	0.000
H66.3 Other chronic suppurative otitis media	0.451	0.548	0.000
H90 Conductive and sensorineural hearing loss	0.451	0.549	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.448	0.552	0.000
H61 Other disorders of external ear	0.444	0.556	0.000
H61.2 Impacted cerumen	0.439	0.561	0.000
H66.4 Suppurative otitis media, unspecified	0.423	0.577	0.000
H72.8 Other perforations of tympanic membrane	0.414	0.585	0.000
H72.2 Other marginal perforations of tympanic membrane	0.412	0.588	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.399	0.601	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.397	0.603	0.000
H93 Other disorders of ear, not elsewhere classified	0.396	0.604	0.000
H92 Otalgia and effusion of ear	0.393	0.607	0.000
H71 Cholesteatoma of middle ear	0.387	0.613	0.000
H61.8 Other specified disorders of external ear	0.384	0.616	0.000
H74 Other disorders of middle ear and mastoid	0.383	0.617	0.000
H90.2 Conductive hearing loss, unspecified	0.380	0.620	0.000
H90.0 Conductive hearing loss, bilateral	0.376	0.624	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.376	0.624	0.000
H73 Other disorders of tympanic membrane	0.374	0.626	0.000
H93.1 Tinnitus	0.369	0.631	0.000
H92.0 Otalgia	0.366	0.634	0.000
H60 Otitis externa	0.363	0.637	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.362	0.638	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.358	0.642	0.000
H68 Eustachian salpingitis and obstruction	0.358	0.642	0.000
H67 Otitis media in diseases classified elsewhere	0.358	0.642	0.000
H69 Other disorders of Eustachian tube	0.358	0.642	0.000
H72.1 Attic perforation of tympanic membrane	0.353	0.646	0.000
H66.0 Acute suppurative otitis media	0.350	0.649	0.000
H72.0 Central perforation of tympanic membrane	0.349	0.651	0.000
H61.1 Non-infective disorders of pinna	0.344	0.656	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.335	0.665	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.333	0.667	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.331	0.669	0.000
H90.3 Sensorineural hearing loss, bilateral	0.331	0.669	0.000
H60.9 Otitis externa, unspecified	0.325	0.675	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.314	0.686	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.312	0.688	0.000
H69.8 Other specified disorders of Eustachian tube	0.302	0.698	0.000
H93.2 Other abnormal auditory perceptions	0.294	0.706	0.000
H73.1 Chronic myringitis	0.289	0.711	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.289	0.711	0.000
H74.4 Polyp of middle ear	0.288	0.712	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.284	0.715	0.000
H74.0 Tympanosclerosis	0.285	0.715	0.000
H93.0 Degenerative and vascular disorders of ear	0.284	0.716	0.000
H60.8 Other otitis externa	0.280	0.720	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.280	0.720	0.000
H70 Mastoiditis and related conditions	0.276	0.724	0.000
H61.3 Acquired stenosis of external ear canal	0.273	0.727	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.272	0.728	0.000
H93.3 Disorders of acoustic nerve	0.269	0.731	0.000
H73.0 Acute myringitis	0.268	0.732	0.000
H60.5 Acute otitis externa, non-infective	0.267	0.733	0.000
H61.9 Disorder of external ear, unspecified	0.264	0.736	0.000
H60.3 Other infective otitis externa	0.262	0.738	0.000
H60.2 Malignant otitis externa	0.260	0.740	0.000
H74.1 Adhesive middle ear disease	0.260	0.740	0.000
H93.8 Other specified disorders of ear	0.257	0.743	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.257	0.743	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.257	0.743	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.257	0.743	0.000
H68.1 Obstruction of Eustachian tube	0.257	0.743	0.000
H68.0 Eustachian salpingitis	0.257	0.743	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.257	0.743	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.257	0.743	0.000
H69.0 Patulous Eustachian tube	0.257	0.743	0.000
H60.0 Abscess of external ear	0.256	0.744	0.000
H91 Other hearing loss	0.254	0.746	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.252	0.748	0.000
H92.2 Otorrhagia	0.243	0.757	0.000
H92.1 Otorrhoea	0.242	0.758	0.000
H73.8 Other specified disorders of tympanic membrane	0.241	0.759	0.000
H93.9 Disorder of ear, unspecified	0.241	0.759	0.000
H90.5 Sensorineural hearing loss, unspecified	0.240	0.760	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.239	0.761	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.239	0.761	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.237	0.763	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.237	0.763	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.237	0.763	0.000
H62.2 Otitis externa in mycoses	0.237	0.763	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.237	0.763	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.237	0.763	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.237	0.763	0.000
H60.4 Cholesteatoma of external ear	0.236	0.764	0.000
H91.8 Other specified hearing loss	0.212	0.788	0.000
H70.2 Petrositis	0.198	0.802	0.000
H70.0 Acute mastoiditis	0.198	0.802	0.000
H80-H83 Diseases of inner ear	0.197	0.803	0.000
H70.8 Other mastoiditis and related conditions	0.197	0.803	0.000
H70.1 Chronic mastoiditis	0.187	0.813	0.000
H91.2 Sudden idiopathic hearing loss	0.187	0.813	0.000
H91.0 Ototoxic hearing loss	0.183	0.817	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.181	0.819	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.181	0.819	0.000
H91.3 Deaf mutism, not elsewhere classified	0.180	0.820	0.000
H69.9 Eustachian tube disorder, unspecified	0.175	0.825	0.000
H91.1 Presbycusis	0.172	0.828	0.000
H60.1 Cellulitis of external ear	0.166	0.834	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.164	0.835	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.142	0.858	0.000
H83 Other diseases of inner ear	0.140	0.860	0.000
H70.9 Mastoiditis, unspecified	0.138	0.862	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.000	0.864	0.136
H61.0 Perichondritis of external ear	0.136	0.864	0.000
H95.1 Other disorders following mastoidectomy	0.128	0.871	0.000
H83.0 Labyrinthitis	0.101	0.899	0.000
H83.8 Other specified diseases of inner ear	0.101	0.899	0.000
H83.3 Noise effects on inner ear	0.101	0.899	0.000
H83.2 Labyrinthine dysfunction	0.101	0.899	0.000
H83.1 Labyrinthine fistula	0.101	0.899	0.000
H80 Otosclerosis	0.099	0.901	0.000
H83.9 Disease of inner ear, unspecified	0.099	0.901	0.000
H81 Disorders of vestibular function	0.086	0.914	0.000
H65 Nonsuppurative otitis media	0.076	0.924	0.000
H80.8 Other otosclerosis	0.071	0.929	0.000
H80.2 Cochlear otosclerosis	0.071	0.929	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.071	0.929	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.071	0.929	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.068	0.932	0.000
H81.8 Other disorders of vestibular function	0.062	0.938	0.000
H81.4 Vertigo of central origin	0.061	0.938	0.000
H81.2 Vestibular neuronitis	0.061	0.939	0.000
H81.1 Benign paroxysmal vertigo	0.058	0.942	0.000
H81.9 Disorder of vestibular function, unspecified	0.057	0.943	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.055	0.945	0.000
H81.3 Other peripheral vertigo	0.055	0.945	0.000
H65.1 Other acute nonsuppurative otitis media	0.052	0.948	0.000
S27.0 Traumatic pneumothorax	0.051	0.949	0.000
H65.0 Acute serous otitis media	0.049	0.950	0.000
H81.0 Meniere's disease	0.040	0.960	0.000
S27 Injury of other and unspecified intrathoracic organs	0.039	0.961	0.000
H65.4 Other chronic nonsuppurative otitis media	0.037	0.963	0.000
H65.2 Chronic serous otitis media	0.036	0.963	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.037	0.963	0.000
S27.3 Other injuries of lung	0.034	0.966	0.000
O16 Unspecified maternal hypertension	0.032	0.968	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.030	0.970	0.000
S20-S29 Injuries to the thorax	0.029	0.971	0.000
H80.9 Otosclerosis, unspecified	0.028	0.971	0.000
S22.20 Fracture of sternum (closed)	0.029	0.971	0.000
S27.9 Injury of unspecified intrathoracic organ	0.028	0.972	0.000
S27.8 Injury of other specified intrathoracic organs	0.028	0.972	0.000
S27.7 Multiple injuries of intrathoracic organs	0.028	0.972	0.000
S27.6 Injury of pleura	0.028	0.972	0.000
S27.5 Injury of thoracic trachea	0.028	0.972	0.000
S27.4 Injury of bronchus	0.028	0.972	0.000
H91.9 Hearing loss, unspecified	0.028	0.972	0.000
S22.2 Fracture of sternum	0.027	0.973	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.027	0.973	0.000
S27.2 Traumatic heamopneumothorax	0.026	0.974	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.026	0.974	0.000
S20 Superficial injury of thorax	0.025	0.974	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.024	0.976	0.000
S22.0 Fracture of thoracic vertebra	0.024	0.976	0.000
S27.1 Traumatic haemothorax	0.023	0.977	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.022	0.978	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.022	0.978	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.021	0.979	0.000
S26 Injury of heart	0.021	0.979	0.000
S25 Injury of blood vessels of thorax	0.021	0.979	0.000
S24 Injury of nerves and spinal cord at thorax level	0.021	0.979	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.020	0.979	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.020	0.979	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.020	0.979	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.020	0.979	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.020	0.979	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.020	0.979	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.020	0.979	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.020	0.979	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.020	0.979	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.020	0.979	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.020	0.979	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.020	0.979	0.000
S22.21 Fracture of sternum (open)	0.020	0.980	0.000
S20.3 Other superficial injuries of front wall of thorax	0.019	0.980	0.000
S22.9 Fracture of bony thorax, part unspecified	0.019	0.981	0.000
S22.8 Fracture of other parts of bony thorax	0.019	0.981	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.019	0.981	0.000
S29 Other and unspecified injuries of thorax	0.019	0.981	0.000
S20.4 Other superficial injuries of back wall of thorax	0.018	0.981	0.000
S20.7 Multiple superficial injuries of thorax	0.018	0.981	0.000
S22.1 Multiple fractures of thoracic spine	0.018	0.982	0.000
S22.5 Flail chest	0.018	0.982	0.000
S21 Open wound of thorax	0.017	0.982	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.017	0.982	0.000
K50.1 Crohn's disease of large intestine	0.000	0.983	0.017
S20.0 Contusion of breast	0.017	0.983	0.000
S22.01 Fracture of thoracic vertebra (open)	0.017	0.983	0.000
S23.4 Sprain and strain of ribs and sternum	0.017	0.983	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.016	0.983	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.016	0.984	0.000
S23.3 Sprain and strain of thoracic spine	0.016	0.984	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.016	0.984	0.000
S23.1 Dislocation of thoracic vertebra	0.016	0.984	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.016	0.984	0.000
S20.1 Other and unspecified superficial injuries of breast	0.015	0.984	0.000
S24.6 Injury of unspecified nerve of thorax	0.015	0.985	0.000
S24.5 Injury of other nerves of thorax	0.015	0.985	0.000
S24.4 Injury of thoracic sympathetic nerves	0.015	0.985	0.000
S24.3 Injury of peripheral nerves of thorax	0.015	0.985	0.000
S24.2 Injury of nerve root of thoracic spine	0.015	0.985	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.015	0.985	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.015	0.985	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.015	0.985	0.000
S25.8 Injury of other blood vessels of thorax	0.015	0.985	0.000
S25.7 Injury of multiple blood vessels of thorax	0.015	0.985	0.000
S25.5 Injury of intercostal blood vessels	0.015	0.985	0.000
S25.4 Injury of pulmonary blood vessels	0.015	0.985	0.000
S25.3 Injury of innominate or subclavian vein	0.015	0.985	0.000
S25.2 Injury of superior vena cava	0.015	0.985	0.000
S25.1 Injury of innominate or subclavian artery	0.015	0.985	0.000
S25.0 Injury of thoracic aorta	0.015	0.985	0.000
S26.9 Injury of heart, unspecified	0.015	0.985	0.000
S26.8 Other injuries of heart	0.015	0.985	0.000
S26.0 Injury of heart with haemopericardium	0.015	0.985	0.000
S28.1 Traumatic amputation of part of thorax	0.015	0.985	0.000
S28.0 Crushed chest	0.015	0.985	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.014	0.986	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.014	0.986	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.014	0.986	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.014	0.986	0.000
S29.8 Other specified injuries of thorax	0.014	0.986	0.000
S29.7 Multiple injuries of thorax	0.014	0.986	0.000
S29.0 Injury of muscle and tendon at thorax level	0.014	0.986	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.013	0.987	0.000
S22.3 Fracture of rib	0.013	0.987	0.000
S22.4 Multiple fractures of ribs	0.013	0.987	0.000
S22.51 Flail chest (open)	0.013	0.987	0.000
K50 Crohn's disease [regional enteritis]	0.000	0.987	0.013
S21.8 Open wound of other parts of thorax	0.013	0.987	0.000
S21.7 Multiple open wounds of thoracic wall	0.013	0.987	0.000
S21.0 Open wound of breast	0.013	0.987	0.000
K50.9 Crohn's disease, unspecified	0.000	0.987	0.013
S21.2 Open wound of back wall of thorax	0.012	0.988	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.012	0.988	0.000
S21.1 Open wound of front wall of thorax	0.012	0.988	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.011	0.988	0.000
S21.9 Open wound of thorax, part unspecified	0.011	0.988	0.000
S29.9 Unspecified injury of thorax	0.011	0.988	0.000
S22.50 Flail chest (closed)	0.011	0.988	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.011	0.989	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.011	0.989	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.011	0.989	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.011	0.989	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.011	0.989	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.011	0.989	0.000
K50.0 Crohn's disease of small intestine	0.000	0.990	0.010
J18.1 Lobar pneumonia, unspecified	0.010	0.990	0.000
S22.31 Fracture of rib (open)	0.010	0.990	0.000
S22.41 Multiple fractures of ribs (open)	0.010	0.990	0.000
K50.8 Other Crohn's disease	0.000	0.991	0.009
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.008	0.992	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.008	0.992	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.008	0.992	0.000
C50.1 Central portion of breast	0.007	0.993	0.000
H65.3 Chronic mucoid otitis media	0.007	0.993	0.001
S86.8 Injury of other muscles and tendons at lower leg level	0.007	0.993	0.000
T78.4 Allergy, unspecified	0.000	0.993	0.007
S20.2 Contusion of thorax	0.005	0.993	0.002
K80.8 Other cholelithiasis	0.007	0.993	0.000
S86 Injury of muscle and tendon at lower leg level	0.006	0.994	0.000
M88.9 Paget's disease of bone, unspecified	0.006	0.994	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O15 Eclampsia	0.006	0.994	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.006	0.994	0.000
N41.9 Inflammatory disease of prostate, unspecified	0.006	0.994	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.994	0.006
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.005	0.995	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.995	0.005
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.005	0.995	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.005	0.995	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.005	0.995	0.000
S86.0 Injury of Achilles tendon	0.005	0.995	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.005	0.995	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.005	0.995	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.005	0.995	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.005	0.995	0.000
M88.98 Paget's disease of bone, unspecified (Other)	0.005	0.995	0.000
M88.97 Paget's disease of bone, unspecified (Ankle and foot)	0.005	0.995	0.000
M88.96 Paget's disease of bone, unspecified (Lower leg)	0.005	0.995	0.000
M88.94 Paget's disease of bone, unspecified (Hand)	0.005	0.995	0.000
M88.93 Paget's disease of bone, unspecified (Forearm)	0.005	0.995	0.000
M88.92 Paget's disease of bone, unspecified (Upper arm)	0.005	0.995	0.000
M88.91 Paget's disease of bone, unspecified (Shoulder region)	0.005	0.995	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.995	0.000
N41.0 Acute prostatitis	0.004	0.995	0.000
N41 Inflammatory diseases of prostate	0.005	0.995	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O15.9 Eclampsia, unspecified as to time period	0.004	0.996	0.000
O15.2 Eclampsia in the puerperium	0.004	0.996	0.000
O15.1 Eclampsia in labour	0.004	0.996	0.000
O15.0 Eclampsia in pregnancy	0.004	0.996	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.996	0.004
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.996	0.004
O12.1 Gestational proteinuria	0.004	0.996	0.000
M88 Paget's disease of bone [osteitis deformans]	0.004	0.996	0.000
T78.8 Other adverse effects, not elsewhere classified	0.000	0.996	0.004
O12.2 Gestational oedema with proteinuria	0.004	0.996	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.996	0.004
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.996	0.004
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.996	0.000
N41.2 Abscess of prostate	0.004	0.996	0.000
O14.0 Moderate preeclampsia	0.004	0.996	0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.000	0.996	0.004
N41.8 Other inflammatory diseases of prostate	0.004	0.996	0.000
O14.2 HELLP syndrome	0.004	0.996	0.000
S86.00 Unspecified injury of Achilles tendon	0.004	0.996	0.000
T78.9 Adverse effect, unspecified	0.000	0.996	0.004
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.996	0.004
M88.8 Paget's disease of other bones	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
N04.9 Unspecified	0.004	0.996	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.996	0.004
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.996	0.004
O12.0 Gestational oedema	0.003	0.996	0.000
S22.30 Fracture of rib (closed)	0.003	0.996	0.000
N41.3 Prostatocystitis	0.003	0.996	0.000
S22.40 Multiple fractures of ribs (closed)	0.003	0.997	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.997	0.003
M88.85 Paget's disease of other bones (Pelvic region and thigh)	0.003	0.997	0.000
M88.0 Paget's disease of skull	0.003	0.997	0.000
N41.1 Chronic prostatitis	0.003	0.997	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.003	0.997	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.003	0.997	0.000
N04 Nephrotic syndrome	0.003	0.997	0.000
N04.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
O14.1 Severe preeclampsia	0.003	0.997	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
Z74.0 Reduced mobility	0.000	0.997	0.003
R22.3 Localised swelling, mass and lump, upper limb	0.003	0.997	0.000
H01.0 Blepharitis	0.000	0.997	0.003
N87.9 Dysplasia of cervix uteri, unspecified	0.003	0.997	0.000
M88.89 Paget's disease of other bones (Site unspecified)	0.003	0.997	0.000
M88.88 Paget's disease of other bones (Other)	0.003	0.997	0.000
M88.87 Paget's disease of other bones (Ankle and foot)	0.003	0.997	0.000
M88.86 Paget's disease of other bones (Lower leg)	0.003	0.997	0.000
M88.84 Paget's disease of other bones (Hand)	0.003	0.997	0.000
M88.83 Paget's disease of other bones (Forearm)	0.003	0.997	0.000
M88.82 Paget's disease of other bones (Upper arm)	0.003	0.997	0.000
M88.81 Paget's disease of other bones (Shoulder region)	0.003	0.997	0.000
M88.80 Paget's disease of other bones (Multiple sites)	0.003	0.997	0.000
D04.6 Skin of upper limb, including shoulder	0.003	0.997	0.000
E23.0 Hypopituitarism	0.003	0.997	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.000	0.997	0.003
N04.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
M88.09 Paget's disease of skull-Site unspec	0.002	0.997	0.000
M88.08 Paget's disease of skull-Other	0.002	0.997	0.000
M88.07 Paget's disease of skull-Ankle/Foot	0.002	0.997	0.000
M88.06 Paget's disease of skull-Lower Leg	0.002	0.997	0.000
M88.05 Paget's disease of skull-Pelvic/Thigh	0.002	0.997	0.000
M88.04 Paget's disease of skull-Hand	0.002	0.997	0.000
M88.03 Paget's disease of skull-Forearm	0.002	0.997	0.000
M88.02 Paget's disease of skull-Upper arm	0.002	0.997	0.000
M88.01 Paget's disease of skull-Shldr region	0.002	0.997	0.000
M88.00 Paget's disease of skull-Mult sites	0.002	0.997	0.000
N04.0 Minor glomerular abnormality	0.002	0.997	0.000
N04.8 Other	0.002	0.997	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.002	0.997	0.000
N04.6 Dense deposit disease	0.002	0.997	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.002	0.997	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.997	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.997	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.000	0.998	0.002
Y60.0 During surgical operation	0.000	0.998	0.002
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
H43.1 Vitreous haemorrhage	0.000	0.998	0.002
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
Z36.8 Other antenatal screening	0.002	0.998	0.000
J38.1 Polyp of vocal cord and larynx	0.002	0.998	0.000
T78.3 Angioneurotic oedema	0.000	0.998	0.002
K35.8 Acute appendicitis, other and unspecified	0.002	0.998	0.000
Z74.8 Other problems related to care-provider dependency	0.000	0.998	0.002
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.002	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.002	0.998	0.000
R52.9 Pain, unspecified	0.000	0.998	0.002
T66-T78 Other and unspecified effects of external causes	0.000	0.998	0.002
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.002	0.998	0.000
R22.7 Localised swelling, mass and lump, multiple sites	0.000	0.998	0.002
S52.10 Fracture of upper end of radius (closed)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
N05.9 Unspecified	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.002
R22.0 Localised swelling, mass and lump, head	0.000	0.998	0.002
Q21.0 Ventricular septal defect	0.002	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M86-M90 Other osteopathies	0.002	0.998	0.000
N05.8 Other	0.002	0.998	0.000
M89.37 Hypertrophy of bone (Ankle and foot)	0.002	0.998	0.000
T66 Unspecified effects of radiation	0.000	0.998	0.002
N00-N08 Glomerular diseases	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.998	0.002
J18.8 Other pneumonia, organism unspecified	0.002	0.998	0.000
R23.4 Changes in skin texture	0.000	0.998	0.002
J18 Pneumonia, organism unspecified	0.002	0.998	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
E14.1 With ketoacidosis	0.002	0.998	0.000
N05.6 Dense deposit disease	0.002	0.998	0.000
N05.4 Diffuse endocapillary proliferative glomerulonephritis	0.002	0.998	0.000
N05.0 Minor glomerular abnormality	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.000	0.998	0.002
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
E23 Hypofunction and other disorders of pituitary gland	0.002	0.998	0.000
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.998	0.000
T74 Maltreatment syndromes	0.000	0.998	0.002
T73 Effects of other deprivation	0.000	0.998	0.002
T70 Effects of air pressure and water pressure	0.000	0.998	0.002
T69 Other effects of reduced temperature	0.000	0.998	0.002
T67 Effects of heat and light	0.000	0.998	0.002
E23.7 Disorder of pituitary gland, unspecified	0.002	0.998	0.000
N05.7 Diffuse crescentic glomerulonephritis	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
Y42.1 Thyroid hormones and substitutes	0.002	0.998	0.000
Y54.5 Other diuretics	0.002	0.998	0.000
T71 Asphyxiation	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.002	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.002	0.998	0.000
M86 Osteomyelitis	0.002	0.998	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
Z74 Problems related to care-provider dependency	0.000	0.998	0.002
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
G51.0 Bell's palsy	0.002	0.998	0.000
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.002	0.998	0.000
T68 Hypothermia	0.000	0.998	0.002
J15.4 Pneumonia due to other streptococci	0.002	0.998	0.000
S41.1 Open wound of upper arm	0.000	0.998	0.002
E23.6 Other disorders of pituitary gland	0.002	0.998	0.000
F05.9 Delirium, unspecified	0.002	0.998	0.000
N05.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.001	0.998	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.002	0.998	0.000
N03.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
Z94.8 Other transplanted organ and tissue status	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.001	0.998	0.000
N06 Isolated proteinuria with specified morphological lesion	0.001	0.998	0.000
N01 Rapidly progressive nephritic syndrome	0.001	0.998	0.000
N00 Acute nephritic syndrome	0.001	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
J18.2 Hypostatic pneumonia, unspecified	0.001	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.002	0.998	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.001	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.001	0.998	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.001	0.998	0.000
E23.1 Drug-induced hypopituitarism	0.001	0.998	0.000
F60 Specific personality disorders	0.000	0.998	0.002
T67.9 Effects of heat and light, unspecified	0.000	0.998	0.001
T67.8 Other effects of heat and light	0.000	0.998	0.001
T67.7 Heat oedema	0.000	0.998	0.001
T67.6 Heat fatigue, transient	0.000	0.998	0.001
T67.5 Heat exhaustion, unspecified	0.000	0.998	0.001
T67.4 Heat exhaustion due to salt depletion	0.000	0.998	0.001
T67.3 Heat exhaustion, anhydrotic	0.000	0.998	0.001
T67.2 Heat cramp	0.000	0.998	0.001
T67.1 Heat syncope	0.000	0.998	0.001
T67.0 Heatstroke and sunstroke	0.000	0.998	0.001
T69.9 Effect of reduced temperature, unspecified	0.000	0.998	0.001
T69.8 Other specified effects of reduced temperature	0.000	0.998	0.001
T69.1 Chilblains	0.000	0.998	0.001
T69.0 Immersion hand and foot	0.000	0.998	0.001
T70.9 Effect of air pressure and water pressure, unspecified	0.000	0.998	0.001
T70.8 Other effects of air pressure and water pressure	0.000	0.998	0.001
T70.4 Effects of high-pressure fluids	0.000	0.998	0.001
T70.2 Other and unspecified effects of high altitude	0.000	0.998	0.001
T70.1 Sinus barotrauma	0.000	0.998	0.001
T70.0 Otitic barotrauma	0.000	0.998	0.001
T73.9 Effect of deprivation, unspecified	0.000	0.998	0.001
T73.8 Other effects of deprivation	0.000	0.998	0.001
T73.3 Exhaustion due to excessive exertion	0.000	0.998	0.001
T73.2 Exhaustion due to exposure	0.000	0.998	0.001
T73.1 Effects of thirst	0.000	0.998	0.001
T73.0 Effects of hunger	0.000	0.998	0.001
T74.9 Maltreatment syndrome, unspecified	0.000	0.998	0.001
T74.8 Other maltreatment syndromes	0.000	0.998	0.001
T74.3 Psychological abuse	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations