TreeWAS – Variant ID: rs11027293

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.0 Congestive heart failure	0.000	0.988	0.012
I50 Heart failure	0.000	0.989	0.011
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.011	0.989	0.000
I51 Complications and ill-defined descriptions of heart disease	0.000	0.990	0.010
O34 Maternal care for known or suspected abnormality of pelvic organs	0.010	0.990	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.010	0.990	0.000
I50.1 Left ventricular failure	0.000	0.991	0.009
I51.7 Cardiomegaly	0.000	0.991	0.009
I30-I52 Other forms of heart disease	0.000	0.991	0.009
O34.2 Maternal care due to uterine scar from previous surgery	0.009	0.991	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.009	0.991	0.000
I51.8 Other ill-defined heart diseases	0.000	0.991	0.009
O69.1 Labour and delivery complicated by cord around neck, with compression	0.009	0.991	0.000
O60-O75 Complications of labour and delivery	0.009	0.991	0.000
O46.9 Antepartum haemorrhage, unspecified	0.009	0.991	0.000
I50.9 Heart failure, unspecified	0.000	0.991	0.009
O48 Prolonged pregnancy	0.009	0.991	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.009	0.991	0.000
O43 Placental disorders	0.008	0.991	0.000
O47 False labour	0.008	0.991	0.000
O44 Placenta praevia	0.008	0.991	0.000
O80-O84 Delivery	0.008	0.992	0.000
O36 Maternal care for other known or suspected foetal problems	0.008	0.992	0.000
I44 Atrioventricular and left bundle-branch block	0.000	0.992	0.008
O30 Multiple gestation	0.008	0.992	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.008	0.992	0.000
I51.9 Heart disease, unspecified	0.000	0.992	0.008
I49 Other cardiac arrhythmias	0.000	0.992	0.008
O45 Premature separation of placenta [abruptio placentae]	0.008	0.992	0.000
O41 Other disorders of amniotic fluid and membranes	0.008	0.992	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.008	0.992	0.000
O33 Maternal care for known or suspected disproportion	0.008	0.992	0.000
O31 Complications specific to multiple gestation	0.008	0.992	0.000
O40 Polyhydramnios	0.008	0.992	0.000
T39.1 4-Aminophenol derivatives	0.008	0.992	0.000
I49.9 Cardiac arrhythmia, unspecified	0.000	0.992	0.008
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.008	0.992	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.008	0.992	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.008	0.992	0.000
O82 Single delivery by Caesarean section	0.008	0.992	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.008	0.992	0.000
I44.0 Atrioventricular block, first degree	0.000	0.992	0.007
O64 Obstructed labour due to malposition and malpresentation of foetus	0.007	0.992	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.993	0.007
I51.5 Myocardial degeneration	0.000	0.993	0.007
I51.4 Myocarditis, unspecified	0.000	0.993	0.007
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.993	0.007
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.993	0.007
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.993	0.007
I51.0 Cardiac septal defect, acquired	0.000	0.993	0.007
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.007	0.993	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.007	0.993	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.007	0.993	0.000
O34.6 Maternal care for abnormality of vagina	0.007	0.993	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.007	0.993	0.000
O34.4 Maternal care for other abnormalities of cervix	0.007	0.993	0.000
O34.3 Maternal care for cervical incompetence	0.007	0.993	0.000
O34.1 Maternal care for tumour of corpus uteri	0.007	0.993	0.000
O34.0 Maternal care for congenital malformation of uterus	0.007	0.993	0.000
I46 Cardiac arrest	0.000	0.993	0.007
O61 Failed induction of labour	0.007	0.993	0.000
I44.1 Atrioventricular block, second degree	0.000	0.993	0.007
O42 Premature rupture of membranes	0.007	0.993	0.000
O46.8 Other antepartum haemorrhage	0.007	0.993	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.007	0.993	0.000
O70 Perineal laceration during delivery	0.007	0.993	0.000
O43.8 Other placental disorders	0.007	0.993	0.000
I31 Other diseases of pericardium	0.000	0.993	0.007
O80 Single spontaneous delivery	0.007	0.993	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.007	0.993	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.007	0.993	0.000
I52 Other heart disorders in diseases classified elsewhere	0.000	0.993	0.007
I48 Atrial fibrillation and flutter	0.000	0.993	0.007
I43 Cardiomyopathy in diseases classified elsewhere	0.000	0.993	0.007
I41 Myocarditis in diseases classified elsewhere	0.000	0.993	0.007
I40 Acute myocarditis	0.000	0.993	0.007
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.000	0.993	0.007
I36 Nonrheumatic tricuspid valve disorders	0.000	0.993	0.007
I32 Pericarditis in diseases classified elsewhere	0.000	0.993	0.007
O44.1 Placenta praevia with haemorrhage	0.007	0.993	0.000
I47 Paroxysmal tachycardia	0.000	0.993	0.007
O36.0 Maternal care for rhesus isoimmunisation	0.007	0.993	0.000
O00-O08 Pregnancy with abortive outcome	0.007	0.993	0.000
N28.1 Cyst of kidney, acquired	0.000	0.993	0.007
O85-O92 Complications predominantly related to the puerperium	0.007	0.993	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.007	0.993	0.000
I44.2 Atrioventricular block, complete	0.000	0.993	0.007
O66 Other obstructed labour	0.007	0.993	0.000
O73 Retained placenta and membranes, without haemorrhage	0.007	0.993	0.000
O62 Abnormalities of forces of labour	0.007	0.993	0.000
I30 Acute pericarditis	0.000	0.993	0.007
I33 Acute and subacute endocarditis	0.000	0.993	0.007
O74 Complications of anaesthesia during labour and delivery	0.007	0.993	0.000
O71 Other obstetric trauma	0.007	0.993	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.007	0.993	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.007	0.993	0.000
O60 Preterm delivery	0.007	0.993	0.000
O30.0 Twin pregnancy	0.007	0.993	0.000
I45 Other conduction disorders	0.000	0.993	0.007
O36.9 Maternal care for foetal problem, unspecified	0.007	0.993	0.000
I34 Nonrheumatic mitral valve disorders	0.000	0.993	0.007
O82.0 Delivery by elective Caesarean section	0.006	0.993	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.993	0.006
O02 Other abnormal products of conception	0.006	0.993	0.000
O69.9 Labour and delivery complicated by cord complication, unspecified	0.006	0.993	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.993	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.006	0.993	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.006	0.993	0.000
O69.3 Labour and delivery complicated by short cord	0.006	0.993	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.006	0.993	0.000
O64.1 Obstructed labour due to breech presentation	0.006	0.994	0.000
T39.0 Salicylates	0.006	0.994	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
I46.0 Cardiac arrest with successful resuscitation	0.000	0.994	0.006
O43.9 Placental disorder, unspecified	0.006	0.994	0.000
O43.2 Morbidly adherent placenta	0.006	0.994	0.000
O43.1 Malformation of placenta	0.006	0.994	0.000
O43.0 Placental transfusion syndromes	0.006	0.994	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.006	0.994	0.000
O82.1 Delivery by emergency Caesarean section	0.006	0.994	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.006	0.994	0.000
O36.4 Maternal care for intra-uterine death	0.006	0.994	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.006	0.994	0.000
O36.2 Maternal care for hydrops foetalis	0.006	0.994	0.000
O36.1 Maternal care for other isoimmunisation	0.006	0.994	0.000
I37 Pulmonary valve disorders	0.000	0.994	0.006
O84 Multiple delivery	0.006	0.994	0.000
O83 Other assisted single delivery	0.006	0.994	0.000
O81 Single delivery by forceps and vacuum extractor	0.006	0.994	0.000
I44.6 Other and unspecified fascicular block	0.000	0.994	0.006
I44.5 Left posterior fascicular block	0.000	0.994	0.006
I44.4 Left anterior fascicular block	0.000	0.994	0.006
I44.3 Other and unspecified atrioventricular block	0.000	0.994	0.006
O63 Long labour	0.006	0.994	0.000
O30.9 Multiple gestation, unspecified	0.006	0.994	0.000
O30.8 Other multiple gestation	0.006	0.994	0.000
O30.2 Quadruplet pregnancy	0.006	0.994	0.000
O30.1 Triplet pregnancy	0.006	0.994	0.000
I35 Nonrheumatic aortic valve disorders	0.000	0.994	0.006
O36.5 Maternal care for poor foetal growth	0.006	0.994	0.000
O36.6 Maternal care for excessive foetal growth	0.006	0.994	0.000
O36.8 Maternal care for other specified foetal problems	0.006	0.994	0.000
O02.1 Missed abortion	0.006	0.994	0.000
O47.0 False labour before 37 completed weeks of gestation	0.006	0.994	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.006	0.994	0.000
O32.8 Maternal care for other malpresentation of foetus	0.006	0.994	0.000
O32.6 Maternal care for compound presentation	0.006	0.994	0.000
O32.4 Maternal care for high head at term	0.006	0.994	0.000
O32.3 Maternal care for face, brow and chin presentation	0.006	0.994	0.000
O32.2 Maternal care for transverse and oblique lie	0.006	0.994	0.000
O32.0 Maternal care for unstable lie	0.006	0.994	0.000
I49.4 Other and unspecified premature depolarisation	0.000	0.994	0.006
I49.2 Junctional premature depolarisation	0.000	0.994	0.006
I49.1 Atrial premature depolarisation	0.000	0.994	0.006
O70.9 Perineal laceration during delivery, unspecified	0.006	0.994	0.000
O31.8 Other complications specific to multiple gestation	0.006	0.994	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.006	0.994	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.006	0.994	0.000
O31.0 Papyraceous foetus	0.006	0.994	0.000
O33.9 Maternal care for disproportion, unspecified	0.006	0.994	0.000
O33.8 Maternal care for disproportion of other origin	0.006	0.994	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.006	0.994	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.006	0.994	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.006	0.994	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.006	0.994	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.006	0.994	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.006	0.994	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.006	0.994	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.006	0.994	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.006	0.994	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.006	0.994	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.006	0.994	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.006	0.994	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.006	0.994	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.006	0.994	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.006	0.994	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.006	0.994	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.006	0.994	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.006	0.994	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.006	0.994	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.006	0.994	0.000
O41.1 Infection of amniotic sac and membranes	0.006	0.994	0.000
O41.0 Oligohydramnios	0.006	0.994	0.000
O45.9 Premature separation of placenta, unspecified	0.006	0.994	0.000
O45.8 Other premature separation of placenta	0.006	0.994	0.000
O45.0 Premature separation of placenta with coagulation defect	0.006	0.994	0.000
O61.0 Failed medical induction of labour	0.006	0.994	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.006	0.994	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.006	0.994	0.000
I38 Endocarditis, valve unspecified	0.000	0.994	0.006
O42.9 Premature rupture of membranes, unspecified	0.006	0.994	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.006	0.994	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.006	0.994	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.006	0.994	0.000
T39.4 Antirheumatics, not elsewhere classified	0.006	0.994	0.000
T39.2 Pyrazolone derivatives	0.006	0.994	0.000
I49.0 Ventricular fibrillation and flutter	0.000	0.994	0.006
J90 Pleural effusion, not elsewhere classified	0.000	0.994	0.006
O16 Unspecified maternal hypertension	0.006	0.994	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O97 Death from sequelae of direct obstetric causes	0.006	0.994	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.006	0.994	0.000
O95 Obstetric death of unspecified cause	0.006	0.994	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.006	0.994	0.000
O80.9 Single spontaneous delivery, unspecified	0.006	0.994	0.000
O82.9 Delivery by Caesarean section, unspecified	0.006	0.994	0.000
O82.8 Other single delivery by Caesarean section	0.006	0.994	0.000
O82.2 Delivery by Caesarean hysterectomy	0.006	0.994	0.000
O70.1 Second degree perineal laceration during delivery	0.006	0.994	0.000
O47.9 False labour, unspecified	0.005	0.994	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.005	0.994	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.005	0.994	0.000
O64.5 Obstructed labour due to compound presentation	0.005	0.994	0.000
O64.4 Obstructed labour due to shoulder presentation	0.005	0.994	0.000
O64.3 Obstructed labour due to brow presentation	0.005	0.994	0.000
O64.2 Obstructed labour due to face presentation	0.005	0.994	0.000
O80.0 Spontaneous vertex delivery	0.006	0.994	0.000
O72 Postpartum haemorrhage	0.005	0.994	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.005	0.994	0.000
I49.3 Ventricular premature depolarisation	0.000	0.994	0.005
I42 Cardiomyopathy	0.000	0.994	0.005
I31.3 Pericardial effusion (noninflammatory)	0.000	0.995	0.005
I46.1 Sudden cardiac death, so described	0.000	0.995	0.005
O61.9 Failed induction of labour, unspecified	0.005	0.995	0.000
O61.8 Other failed induction of labour	0.005	0.995	0.000
O61.1 Failed instrumental induction of labour	0.005	0.995	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.005	0.995	0.000
H02 Other disorders of eyelid	0.005	0.995	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.995	0.005
O20-O29 Other maternal disorders predominantly related to pregnancy	0.005	0.995	0.000
O63.1 Prolonged second stage (of labour)	0.005	0.995	0.000
O70.3 Fourth degree perineal laceration during delivery	0.005	0.995	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.005	0.995	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.005	0.995	0.000
I47.1 Supraventricular tachycardia	0.000	0.995	0.005
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.005	0.995	0.000
I31.8 Other specified diseases of pericardium	0.000	0.995	0.005
I31.2 Haemopericardium, not elsewhere classified	0.000	0.995	0.005
I31.1 Chronic constrictive pericarditis	0.000	0.995	0.005
I31.0 Chronic adhesive pericarditis	0.000	0.995	0.005
O80.8 Other single spontaneous delivery	0.005	0.995	0.000
O80.1 Spontaneous breech delivery	0.005	0.995	0.000
O02.0 Blighted ovum and nonhydatidiform mole	0.005	0.995	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.005	0.995	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.000	0.995	0.005
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.000	0.995	0.005
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.000	0.995	0.005
I36.8 Other nonrheumatic tricuspid valve disorders	0.000	0.995	0.005
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.000	0.995	0.005
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.000	0.995	0.005
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.000	0.995	0.005
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.000	0.995	0.005
I39.4 Multiple valve disorders in diseases classified elsewhere	0.000	0.995	0.005
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.000	0.995	0.005
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.000	0.995	0.005
I39.1 Aortic valve disorders in diseases classified elsewhere	0.000	0.995	0.005
I39.0 Mitral valve disorders in diseases classified elsewhere	0.000	0.995	0.005
I40.9 Acute myocarditis, unspecified	0.000	0.995	0.005
I40.8 Other acute myocarditis	0.000	0.995	0.005
I40.1 Isolated myocarditis	0.000	0.995	0.005
I40.0 Infective myocarditis	0.000	0.995	0.005
I41.8 Myocarditis in other diseases classified elsewhere	0.000	0.995	0.005
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
I41.1 Myocarditis in viral diseases classified elsewhere	0.000	0.995	0.005
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.000	0.995	0.005
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.000	0.995	0.005
I43.2 Cardiomyopathy in nutritional diseases	0.000	0.995	0.005
I43.1 Cardiomyopathy in metabolic diseases	0.000	0.995	0.005
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.000	0.995	0.005
I48.4 Atypical atrial flutter	0.000	0.995	0.005
I48.3 Typical atrial flutter	0.000	0.995	0.005
I48.2 Chronic atrial fibrillation	0.000	0.995	0.005
I48.1 Persistent atrial fibrillation	0.000	0.995	0.005
I48.0 Paroxysmal atrial fibrillation	0.000	0.995	0.005
I52.8 Other heart disorders in other diseases classified elsewhere	0.000	0.995	0.005
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.995	0.005
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.000	0.995	0.005
O15 Eclampsia	0.005	0.995	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.005	0.995	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.005	0.995	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.000	0.995	0.005
I47.0 Reentry ventricular arrhythmia	0.000	0.995	0.005
O08 Complications following abortion and ectopic and molar pregnancy	0.005	0.995	0.000
O07 Failed attempted abortion	0.005	0.995	0.000
O06 Unspecified abortion	0.005	0.995	0.000
O05 Other abortion	0.005	0.995	0.000
O01 Hydatidiform mole	0.005	0.995	0.000
O00 Ectopic pregnancy	0.005	0.995	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.005	0.995	0.000
O91 Infections of breast associated with childbirth	0.005	0.995	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.995	0.000
O89 Complications of anaesthesia during the puerperium	0.005	0.995	0.000
O88 Obstetric embolism	0.005	0.995	0.000
O87 Venous complications in the puerperium	0.005	0.995	0.000
O86 Other puerperal infections	0.005	0.995	0.000
O85 Puerperal sepsis	0.005	0.995	0.000
O62.2 Other uterine inertia	0.005	0.995	0.000
O73.0 Retained placenta, without haemorrhage	0.005	0.995	0.000
O75.9 Complication of labour and delivery, unspecified	0.005	0.995	0.000
O75.8 Other specified complications of labour and delivery	0.005	0.995	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.005	0.995	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.005	0.995	0.000
O75.4 Other complications of obstetric surgery and procedures	0.005	0.995	0.000
O75.3 Other infection during labour	0.005	0.995	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.005	0.995	0.000
O75.1 Shock during or following labour and delivery	0.005	0.995	0.000
O75.0 Maternal distress during labour and delivery	0.005	0.995	0.000
O66.9 Obstructed labour, unspecified	0.005	0.995	0.000
O66.8 Other specified obstructed labour	0.005	0.995	0.000
O66.4 Failed trial of labour, unspecified	0.005	0.995	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.005	0.995	0.000
O66.2 Obstructed labour due to unusually large foetus	0.005	0.995	0.000
O66.1 Obstructed labour due to locked twins	0.005	0.995	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.005	0.995	0.000
O70.2 Third degree perineal laceration during delivery	0.005	0.995	0.000
I49.5 Sick sinus syndrome	0.000	0.995	0.005
I31.9 Disease of pericardium, unspecified	0.000	0.995	0.005
O62.9 Abnormality of forces of labour, unspecified	0.005	0.995	0.000
O62.8 Other abnormalities of forces of labour	0.005	0.995	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.005	0.995	0.000
O62.3 Precipitate labour	0.005	0.995	0.000
O62.1 Secondary uterine inertia	0.005	0.995	0.000
O62.0 Primary inadequate contractions	0.005	0.995	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.005	0.995	0.000
I30.8 Other forms of acute pericarditis	0.000	0.995	0.005
I30.1 Infective pericarditis	0.000	0.995	0.005
I30.0 Acute nonspecific idiopathic pericarditis	0.000	0.995	0.005
I33.9 Acute endocarditis, unspecified	0.000	0.995	0.005
I45.9 Conduction disorder, unspecified	0.000	0.995	0.005
I45.8 Other specified conduction disorders	0.000	0.995	0.005
I45.5 Other specified heart block	0.000	0.995	0.005
I45.4 Nonspecific intraventricular block	0.000	0.995	0.005
I45.3 Trifascicular block	0.000	0.995	0.005
I45.2 Bifascicular block	0.000	0.995	0.005
I45.0 Right fascicular block	0.000	0.995	0.005
O60.3 Preterm delivery without spontaneous labour	0.005	0.995	0.000
O60.2 Preterm spontaneous labour with term delivery	0.005	0.995	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.005	0.995	0.000
O60.0 Preterm labour without delivery	0.005	0.995	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.005	0.995	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.005	0.995	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.005	0.995	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.005	0.995	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.005	0.995	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.005	0.995	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.005	0.995	0.000
O65.0 Obstructed labour due to deformed pelvis	0.005	0.995	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.005	0.995	0.000
O67.8 Other intrapartum haemorrhage	0.005	0.995	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.005	0.995	0.000
O71.9 Obstetric trauma, unspecified	0.005	0.995	0.000
O71.8 Other specified obstetric trauma	0.005	0.995	0.000
O71.7 Obstetric haematoma of pelvis	0.005	0.995	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.995	0.000
O71.5 Other obstetric injury to pelvic organs	0.005	0.995	0.000
O71.4 Obstetric high vaginal laceration alone	0.005	0.995	0.000
O71.3 Obstetric laceration of cervix	0.005	0.995	0.000
O71.2 Postpartum inversion of uterus	0.005	0.995	0.000
O71.1 Rupture of uterus during labour	0.005	0.995	0.000
O71.0 Rupture of uterus before onset of labour	0.005	0.995	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.005	0.995	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.005	0.995	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.005	0.995	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.005	0.995	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.005	0.995	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.005	0.995	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.000	0.995	0.005
I34.8 Other nonrheumatic mitral valve disorders	0.000	0.995	0.005
I34.2 Nonrheumatic mitral (valve) stenosis	0.000	0.995	0.005
I45.1 Other and unspecified right bundle-branch block	0.000	0.995	0.005
H02.8 Other specified disorders of eyelid	0.005	0.995	0.000
I47.2 Ventricular tachycardia	0.000	0.995	0.005
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I44.7 Left bundle-branch block, unspecified	0.000	0.995	0.005
N28.8 Other specified disorders of kidney and ureter	0.000	0.995	0.005
I34.1 Mitral (valve) prolapse	0.000	0.995	0.005
O02.9 Abnormal product of conception, unspecified	0.005	0.995	0.000
O02.8 Other specified abnormal products of conception	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
I30.9 Acute pericarditis, unspecified	0.000	0.995	0.005
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I35.0 Aortic (valve) stenosis	0.000	0.995	0.005
O32.1 Maternal care for breech presentation	0.005	0.995	0.000
I33.0 Acute and subacute infective endocarditis	0.000	0.995	0.005
I37.9 Pulmonary valve disorder, unspecified	0.000	0.995	0.005
I37.8 Other pulmonary valve disorders	0.000	0.995	0.005
I37.2 Pulmonary valve stenosis with insufficiency	0.000	0.995	0.005
I37.0 Pulmonary valve stenosis	0.000	0.995	0.005
O81.5 Delivery by combination of forceps and vacuum extractor	0.005	0.995	0.000
O81.4 Vacuum extractor delivery	0.005	0.995	0.000
O81.3 Other and unspecified forceps delivery	0.005	0.995	0.000
O81.2 Mid-cavity forceps with rotation	0.005	0.995	0.000
O81.1 Mid-cavity forceps delivery	0.005	0.995	0.000
O81.0 Low forceps delivery	0.005	0.995	0.000
O83.9 Assisted single delivery, unspecified	0.005	0.995	0.000
O83.8 Other specified assisted single delivery	0.005	0.995	0.000
O83.4 Destructive operation for delivery	0.005	0.995	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.005	0.995	0.000
O83.2 Other manipulation-assisted delivery	0.005	0.995	0.000
O83.1 Other assisted breech delivery	0.005	0.995	0.000
O83.0 Breech extraction	0.005	0.995	0.000
O84.9 Multiple delivery, unspecified	0.005	0.995	0.000
O84.8 Other multiple delivery	0.005	0.995	0.000
O84.2 Multiple delivery, all by Caesarean section	0.005	0.995	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.005	0.995	0.000
O84.0 Multiple delivery, all spontaneous	0.005	0.995	0.000
I34.0 Mitral (valve) insufficiency	0.000	0.995	0.005
O63.9 Long labour, unspecified	0.005	0.995	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.005	0.995	0.000
I35.9 Aortic valve disorder, unspecified	0.000	0.995	0.005
I35.8 Other aortic valve disorders	0.000	0.995	0.005
I45.6 Preexcitation syndrome	0.000	0.995	0.005
H02.4 Ptosis of eyelid	0.005	0.995	0.000
O70.0 First degree perineal laceration during delivery	0.005	0.995	0.000
H02.3 Blepharochalasis	0.005	0.995	0.000
H02.1 Ectropion of eyelid	0.005	0.995	0.000
H02.6 Xanthelasma of eyelid	0.005	0.995	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.995	0.000
H02.0 Entropion and trichiasis of eyelid	0.005	0.995	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.995	0.004
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.004	0.995	0.000
O04 Medical abortion	0.004	0.995	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.000	0.996	0.004
H40 Glaucoma	0.004	0.996	0.000
I46.9 Cardiac arrest, unspecified	0.000	0.996	0.004
H02.5 Other disorders affecting eyelid function	0.004	0.996	0.000
O96.9 Death from unspecified obstetric cause	0.004	0.996	0.000
O96.1 Death from indirect obstetric cause	0.004	0.996	0.000
O96.0 Death from direct obstetric cause	0.004	0.996	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.004	0.996	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.004	0.996	0.000
O97.0 Death from sequelae of direct obstetric cause	0.004	0.996	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.004	0.996	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.996	0.004
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
H35.3 Degeneration of macula and posterior pole	0.004	0.996	0.000
H40.0 Glaucoma suspect	0.004	0.996	0.000
H35 Other retinal disorders	0.004	0.996	0.000
O72.3 Postpartum coagulation defects	0.004	0.996	0.000
O72.0 Third-stage haemorrhage	0.004	0.996	0.000
I42.8 Other cardiomyopathies	0.000	0.996	0.004
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.996	0.004
I42.6 Alcoholic cardiomyopathy	0.000	0.996	0.004
I42.5 Other restrictive cardiomyopathy	0.000	0.996	0.004
I42.4 Endocardial fibroelastosis	0.000	0.996	0.004
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.996	0.004
I42.2 Other hypertrophic cardiomyopathy	0.000	0.996	0.004
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.996	0.004
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.004	0.996	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.004	0.996	0.000
H40-H42 Glaucoma	0.004	0.996	0.000
I37.1 Pulmonary valve insufficiency	0.000	0.996	0.004
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.004	0.996	0.000
O14.9 Preeclampsia, unspecified	0.004	0.996	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.004	0.996	0.000
H02.2 Lagophthalmos	0.004	0.996	0.000
O29 Complications of anaesthesia during pregnancy	0.004	0.996	0.000
O28 Abnormal findings on antenatal screening of mother	0.004	0.996	0.000
O24 Diabetes mellitus in pregnancy	0.004	0.996	0.000
O23 Infections of genito-urinary tract in pregnancy	0.004	0.996	0.000
O22 Venous complications in pregnancy	0.004	0.996	0.000
O21 Excessive vomiting in pregnancy	0.004	0.996	0.000
O25 Malnutrition in pregnancy	0.004	0.996	0.000
Chapter VII Diseases of the eye and adnexa	0.004	0.996	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.996	0.004
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.996	0.000
O14.2 HELLP syndrome	0.004	0.996	0.000
O14.1 Severe preeclampsia	0.004	0.996	0.000
O14.0 Moderate preeclampsia	0.004	0.996	0.000
H35.0 Background retinopathy and retinal vascular changes	0.004	0.996	0.000
H40.1 Primary open-angle glaucoma	0.004	0.996	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.996	0.004
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations