TreeWAS – Variant ID: rs11049300

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
O60-O75 Complications of labour and delivery	0.103	0.897
O70 Perineal laceration during delivery	0.099	0.901
O68 Labour and delivery complicated by foetal stress [distress]	0.099	0.901
O70.1 Second degree perineal laceration during delivery	0.098	0.902
Chapter XV Pregnancy, childbirth and the puerperium	0.098	0.902
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.095	0.905
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.094	0.906
O69 Labour and delivery complicated by umbilical cord complications	0.094	0.906
O20-O29 Other maternal disorders predominantly related to pregnancy	0.092	0.908
O36 Maternal care for other known or suspected foetal problems	0.090	0.910
O36.8 Maternal care for other specified foetal problems	0.089	0.911
O66 Other obstructed labour	0.085	0.915
O62 Abnormalities of forces of labour	0.084	0.916
O48 Prolonged pregnancy	0.084	0.916
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.083	0.917
O32 Maternal care for known or suspected malpresentation of foetus	0.082	0.918
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.082	0.918
O20 Haemorrhage in early pregnancy	0.080	0.920
O23 Infections of genito-urinary tract in pregnancy	0.078	0.922
O69.8 Labour and delivery complicated by other cord complications	0.078	0.922
O26 Maternal care for other conditions predominantly related to pregnancy	0.077	0.923
O69.1 Labour and delivery complicated by cord around neck, with compression	0.077	0.923
O36.0 Maternal care for rhesus isoimmunisation	0.077	0.923
O69.9 Labour and delivery complicated by cord complication, unspecified	0.076	0.924
O63 Long labour	0.076	0.924
O32.0 Maternal care for unstable lie	0.075	0.925
O20.0 Threatened abortion	0.074	0.926
O80-O84 Delivery	0.074	0.926
O61 Failed induction of labour	0.074	0.926
O74 Complications of anaesthesia during labour and delivery	0.074	0.926
O65 Obstructed labour due to maternal pelvic abnormality	0.074	0.926
O60 Preterm delivery	0.074	0.926
O70.0 First degree perineal laceration during delivery	0.073	0.927
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.073	0.927
O71 Other obstetric trauma	0.072	0.928
O85-O92 Complications predominantly related to the puerperium	0.072	0.928
O62.0 Primary inadequate contractions	0.072	0.928
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.072	0.928
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.072	0.928
O00-O08 Pregnancy with abortive outcome	0.072	0.928
O70.9 Perineal laceration during delivery, unspecified	0.071	0.928
O70.3 Fourth degree perineal laceration during delivery	0.071	0.928
O35 Maternal care for known or suspected foetal abnormality and damage	0.071	0.929
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.071	0.929
O44 Placenta praevia	0.069	0.931
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.069	0.931
O69.2 Labour and delivery complicated by other cord entanglement	0.068	0.932
O42 Premature rupture of membranes	0.068	0.932
O45 Premature separation of placenta [abruptio placentae]	0.068	0.932
O33 Maternal care for known or suspected disproportion	0.068	0.932
O31 Complications specific to multiple gestation	0.068	0.932
O69.5 Labour and delivery complicated by vascular lesion of cord	0.067	0.933
O69.4 Labour and delivery complicated by vasa praevia	0.067	0.933
O69.3 Labour and delivery complicated by short cord	0.067	0.933
O69.0 Labour and delivery complicated by prolapse of cord	0.067	0.933
O64 Obstructed labour due to malposition and malpresentation of foetus	0.067	0.933
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.066	0.934
O29 Complications of anaesthesia during pregnancy	0.066	0.934
O28 Abnormal findings on antenatal screening of mother	0.066	0.934
O22 Venous complications in pregnancy	0.066	0.934
O25 Malnutrition in pregnancy	0.066	0.934
O32.3 Maternal care for face, brow and chin presentation	0.066	0.934
O73 Retained placenta and membranes, without haemorrhage	0.065	0.934
O43 Placental disorders	0.065	0.935
O70.2 Third degree perineal laceration during delivery	0.065	0.935
O62.3 Precipitate labour	0.065	0.935
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.064	0.935
O36.4 Maternal care for intra-uterine death	0.064	0.935
O36.3 Maternal care for signs of foetal hypoxia	0.064	0.935
O36.2 Maternal care for hydrops foetalis	0.064	0.935
O36.1 Maternal care for other isoimmunisation	0.064	0.935
O63.0 Prolonged first stage (of labour)	0.064	0.936
O30 Multiple gestation	0.064	0.936
O21 Excessive vomiting in pregnancy	0.064	0.936
O41 Other disorders of amniotic fluid and membranes	0.064	0.936
O24 Diabetes mellitus in pregnancy	0.064	0.936
O26.2 Pregnancy care of habitual aborter	0.063	0.937
O66.0 Obstructed labour due to shoulder dystocia	0.063	0.937
O40 Polyhydramnios	0.063	0.937
O47 False labour	0.062	0.938
O32.2 Maternal care for transverse and oblique lie	0.062	0.938
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.062	0.938
O23.5 Infections of the genital tract in pregnancy	0.061	0.938
O66.9 Obstructed labour, unspecified	0.061	0.939
O66.8 Other specified obstructed labour	0.061	0.939
O66.4 Failed trial of labour, unspecified	0.061	0.939
O66.3 Obstructed labour due to other abnormalities of foetus	0.061	0.939
O66.2 Obstructed labour due to unusually large foetus	0.061	0.939
O66.1 Obstructed labour due to locked twins	0.061	0.939
O36.9 Maternal care for foetal problem, unspecified	0.061	0.939
O02 Other abnormal products of conception	0.061	0.939
O62.9 Abnormality of forces of labour, unspecified	0.060	0.939
O62.8 Other abnormalities of forces of labour	0.060	0.939
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.060	0.939
O62.1 Secondary uterine inertia	0.060	0.939
O46 Antepartum haemorrhage, not elsewhere classified	0.060	0.940
O94-O99 Other obstetric conditions, not elsewhere classified	0.060	0.940
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.059	0.941
O32.9 Maternal care for malpresentation of foetus, unspecified	0.059	0.941
O32.6 Maternal care for compound presentation	0.059	0.941
O32.4 Maternal care for high head at term	0.059	0.941
O80 Single spontaneous delivery	0.058	0.942
O26.9 Pregnancy-related condition, unspecified	0.058	0.942
O20.8 Other haemorrhage in early pregnancy	0.058	0.942
O02.0 Blighted ovum and nonhydatidiform mole	0.057	0.943
O36.6 Maternal care for excessive foetal growth	0.056	0.944
O23.3 Infections of other parts of urinary tract in pregnancy	0.056	0.944
O23.2 Infections of urethra in pregnancy	0.056	0.944
O23.1 Infections of bladder in pregnancy	0.056	0.944
O23.0 Infections of kidney in pregnancy	0.056	0.944
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.056	0.944
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.056	0.944
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.055	0.944
O26.5 Maternal hypotension syndrome	0.055	0.944
O26.4 Herpes gestationis	0.055	0.944
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.055	0.944
O26.1 Low weight gain in pregnancy	0.055	0.944
O26.0 Excessive weight gain in pregnancy	0.055	0.944
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.055	0.945
O03 Spontaneous abortion	0.055	0.945
O63.2 Delayed delivery of second twin, triplet, etc.	0.055	0.945
O32.8 Maternal care for other malpresentation of foetus	0.054	0.945
O87 Venous complications in the puerperium	0.054	0.945
O42.9 Premature rupture of membranes, unspecified	0.054	0.946
O61.0 Failed medical induction of labour	0.053	0.946
O84 Multiple delivery	0.053	0.947
O83 Other assisted single delivery	0.053	0.947
O81 Single delivery by forceps and vacuum extractor	0.053	0.947
O61.9 Failed induction of labour, unspecified	0.053	0.947
O61.8 Other failed induction of labour	0.053	0.947
O61.1 Failed instrumental induction of labour	0.053	0.947
O60.3 Preterm delivery without spontaneous labour	0.053	0.947
O60.2 Preterm spontaneous labour with term delivery	0.053	0.947
O60.1 Preterm spontaneous labour with preterm delivery	0.053	0.947
O60.0 Preterm labour without delivery	0.053	0.947
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.053	0.947
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.053	0.947
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.053	0.947
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.053	0.947
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.053	0.947
O65.2 Obstructed labour due to pelvic inlet contraction	0.053	0.947
O65.1 Obstructed labour due to generally contracted pelvis	0.053	0.947
O65.0 Obstructed labour due to deformed pelvis	0.053	0.947
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.053	0.947
O74.8 Other complications of anaesthesia during labour and delivery	0.053	0.947
O74.7 Failed or difficult intubation during labour and delivery	0.053	0.947
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.053	0.947
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.053	0.947
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.053	0.947
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.053	0.947
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.053	0.947
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.053	0.947
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.053	0.947
O62.2 Other uterine inertia	0.053	0.947
O67.8 Other intrapartum haemorrhage	0.052	0.947
O67.0 Intrapartum haemorrhage with coagulation defect	0.052	0.947
O90 Complications of the puerperium, not elsewhere classified	0.052	0.948
O71.9 Obstetric trauma, unspecified	0.052	0.948
O71.8 Other specified obstetric trauma	0.052	0.948
O71.7 Obstetric haematoma of pelvis	0.052	0.948
O71.6 Obstetric damage to pelvic joints and ligaments	0.052	0.948
O71.5 Other obstetric injury to pelvic organs	0.052	0.948
O71.3 Obstetric laceration of cervix	0.052	0.948
O71.2 Postpartum inversion of uterus	0.052	0.948
O71.1 Rupture of uterus during labour	0.052	0.948
O71.0 Rupture of uterus before onset of labour	0.052	0.948
O63.9 Long labour, unspecified	0.052	0.948
O92 Other disorders of breast and lactation associated with childbirth	0.052	0.948
O91 Infections of breast associated with childbirth	0.052	0.948
O89 Complications of anaesthesia during the puerperium	0.052	0.948
O88 Obstetric embolism	0.052	0.948
O85 Puerperal sepsis	0.052	0.948
O15 Eclampsia	0.052	0.948
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.052	0.948
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.052	0.948
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.052	0.948
O23.4 Unspecified infection of urinary tract in pregnancy	0.052	0.948
O44.1 Placenta praevia with haemorrhage	0.052	0.948
O67.9 Intrapartum haemorrhage, unspecified	0.051	0.948
O08 Complications following abortion and ectopic and molar pregnancy	0.051	0.948
O07 Failed attempted abortion	0.051	0.948
O06 Unspecified abortion	0.051	0.948
O05 Other abortion	0.051	0.948
O01 Hydatidiform mole	0.051	0.948
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.051	0.948
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.051	0.948
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.051	0.948
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.051	0.948
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.051	0.948
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.051	0.948
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.051	0.948
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.051	0.948
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.051	0.948
O82 Single delivery by Caesarean section	0.051	0.949
O80.9 Single spontaneous delivery, unspecified	0.051	0.949
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.051	0.949
O71.4 Obstetric high vaginal laceration alone	0.051	0.949
O86 Other puerperal infections	0.050	0.949
O34 Maternal care for known or suspected abnormality of pelvic organs	0.050	0.950
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.050	0.950
O44.0 Placenta praevia specified as without haemorrhage	0.050	0.950
O14.0 Moderate preeclampsia	0.050	0.950
O20.9 Haemorrhage in early pregnancy, unspecified	0.049	0.951
O42.2 Premature rupture of membranes, labour delayed by therapy	0.049	0.951
O31.8 Other complications specific to multiple gestation	0.049	0.951
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.049	0.951
O31.1 Continuing pregnancy after abortion of one foetus or more	0.049	0.951
O31.0 Papyraceous foetus	0.049	0.951
O33.9 Maternal care for disproportion, unspecified	0.049	0.951
O33.8 Maternal care for disproportion of other origin	0.049	0.951
O33.7 Maternal care for disproportion due to other foetal deformities	0.049	0.951
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.049	0.951
O33.5 Maternal care for disproportion due to unusually large foetus	0.049	0.951
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.049	0.951
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.049	0.951
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.049	0.951
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.049	0.951
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.049	0.951
O45.9 Premature separation of placenta, unspecified	0.049	0.951
O45.8 Other premature separation of placenta	0.049	0.951
O45.0 Premature separation of placenta with coagulation defect	0.049	0.951
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.048	0.952
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.048	0.952
O64.8 Obstructed labour due to other malposition and malpresentation	0.048	0.952
O64.5 Obstructed labour due to compound presentation	0.048	0.952
O64.4 Obstructed labour due to shoulder presentation	0.048	0.952
O64.3 Obstructed labour due to brow presentation	0.048	0.952
O64.2 Obstructed labour due to face presentation	0.048	0.952
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.048	0.952
O47.1 False labour at or after 37 completed weeks of gestation	0.048	0.952
O22.9 Venous complication in pregnancy, unspecified	0.048	0.952
O22.8 Other venous complications in pregnancy	0.048	0.952
O22.5 Cerebral venous thrombosis in pregnancy	0.048	0.952
O22.4 Haemorrhoids in pregnancy	0.048	0.952
O22.3 Deep phlebothrombosis in pregnancy	0.048	0.952
O22.2 Superficial thrombophlebitis in pregnancy	0.048	0.952
O22.1 Genital varices in pregnancy	0.048	0.952
O22.0 Varicose veins of lower extremity in pregnancy	0.048	0.952
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.048	0.952
O28.8 Other abnormal findings on antenatal screening of mother	0.048	0.952
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.048	0.952
O28.4 Abnormal radiological finding on antenatal screening of mother	0.048	0.952
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.048	0.952
O28.2 Abnormal cytological finding on antenatal screening of mother	0.048	0.952
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.048	0.952
O28.0 Abnormal haematological finding on antenatal screening of mother	0.048	0.952
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.048	0.952
O29.8 Other complications of anaesthesia during pregnancy	0.048	0.952
O29.6 Failed or difficult intubation during pregnancy	0.048	0.952
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.048	0.952
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.048	0.952
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.048	0.952
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.048	0.952
O29.1 Cardiac complications of anaesthesia during pregnancy	0.048	0.952
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.048	0.952
O00 Ectopic pregnancy	0.047	0.952
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.047	0.953
O43.9 Placental disorder, unspecified	0.047	0.953
O43.2 Morbidly adherent placenta	0.047	0.953
O43.1 Malformation of placenta	0.047	0.953
O43.0 Placental transfusion syndromes	0.047	0.953
O30.9 Multiple gestation, unspecified	0.046	0.954
O30.8 Other multiple gestation	0.046	0.954
O30.2 Quadruplet pregnancy	0.046	0.954
O30.1 Triplet pregnancy	0.046	0.954
O21.9 Vomiting of pregnancy, unspecified	0.046	0.954
O21.8 Other vomiting complicating pregnancy	0.046	0.954
O21.2 Late vomiting of pregnancy	0.046	0.954
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.046	0.954
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.046	0.954
O41.1 Infection of amniotic sac and membranes	0.046	0.954
O24.9 Diabetes mellitus in pregnancy, unspecified	0.046	0.954
O24.3 Pre-existing diabetes mellitus, unspecified	0.046	0.954
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.046	0.954
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.046	0.954
O63.1 Prolonged second stage (of labour)	0.045	0.954
O16 Unspecified maternal hypertension	0.045	0.955
O41.8 Other specified disorders of amniotic fluid and membranes	0.045	0.955
O43.8 Other placental disorders	0.044	0.956
O80.8 Other single spontaneous delivery	0.044	0.956
O21.0 Mild hyperemesis gravidarum	0.044	0.956
O75 Other complications of labour and delivery, not elsewhere classified	0.044	0.956
O02.9 Abnormal product of conception, unspecified	0.044	0.956
O02.8 Other specified abnormal products of conception	0.044	0.956
O41.0 Oligohydramnios	0.043	0.956
O46.8 Other antepartum haemorrhage	0.043	0.957
O46.0 Antepartum haemorrhage with coagulation defect	0.043	0.957
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.043	0.957
O97 Death from sequelae of direct obstetric causes	0.043	0.957
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.043	0.957
O95 Obstetric death of unspecified cause	0.043	0.957
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.043	0.957
O82.1 Delivery by emergency Caesarean section	0.043	0.957
O30.0 Twin pregnancy	0.043	0.957
O47.0 False labour before 37 completed weeks of gestation	0.042	0.957
O14.2 HELLP syndrome	0.042	0.958
O14.1 Severe preeclampsia	0.042	0.958
O03.9 Complete or unspecified, without complication	0.042	0.958
O80.1 Spontaneous breech delivery	0.042	0.958
O14.9 Preeclampsia, unspecified	0.042	0.958
O87.2 Haemorrhoids in the puerperium	0.042	0.958
O64.1 Obstructed labour due to breech presentation	0.041	0.958
O03.4 Incomplete, without complication	0.041	0.959
O24.4 Diabetes mellitus arising in pregnancy	0.040	0.959
O03.8 Complete or unspecified, with other and unspecified complications	0.040	0.960
O03.7 Complete or unspecified, complicated by embolism	0.040	0.960
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.040	0.960
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.040	0.960
O03.3 Incomplete, with other and unspecified complications	0.040	0.960
O03.2 Incomplete, complicated by embolism	0.040	0.960
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.040	0.960
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.040	0.960
O87.9 Venous complication in the puerperium, unspecified	0.039	0.961
O87.8 Other venous complications in the puerperium	0.039	0.961
O87.3 Cerebral venous thrombosis in the puerperium	0.039	0.961
O87.1 Deep phlebothrombosis in the puerperium	0.039	0.961
O87.0 Superficial thrombophlebitis in the puerperium	0.039	0.961
O34.4 Maternal care for other abnormalities of cervix	0.039	0.961
O72 Postpartum haemorrhage	0.039	0.961
O73.0 Retained placenta, without haemorrhage	0.039	0.961
O81.5 Delivery by combination of forceps and vacuum extractor	0.038	0.961
O81.4 Vacuum extractor delivery	0.038	0.961
O81.3 Other and unspecified forceps delivery	0.038	0.961
O81.2 Mid-cavity forceps with rotation	0.038	0.961
O81.1 Mid-cavity forceps delivery	0.038	0.961
O81.0 Low forceps delivery	0.038	0.961
O83.9 Assisted single delivery, unspecified	0.038	0.961
O83.8 Other specified assisted single delivery	0.038	0.961
O83.4 Destructive operation for delivery	0.038	0.961
O83.3 Delivery of viable foetus in abdominal pregnancy	0.038	0.961
O83.2 Other manipulation-assisted delivery	0.038	0.961
O83.1 Other assisted breech delivery	0.038	0.961
O83.0 Breech extraction	0.038	0.961
O84.9 Multiple delivery, unspecified	0.038	0.961
O84.8 Other multiple delivery	0.038	0.961
O84.2 Multiple delivery, all by Caesarean section	0.038	0.961
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.038	0.961
O84.0 Multiple delivery, all spontaneous	0.038	0.961
O47.9 False labour, unspecified	0.038	0.962
O36.5 Maternal care for poor foetal growth	0.038	0.962
O90.8 Other complications of the puerperium, not elsewhere classified	0.038	0.962
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.037	0.962
O90.9 Complication of the puerperium, unspecified	0.037	0.962
O90.5 Postpartum thyroiditis	0.037	0.962
O90.4 Postpartum acute renal failure	0.037	0.962
O90.3 Cardiomyopathy in the puerperium	0.037	0.962
O90.2 Haematoma of obstetric wound	0.037	0.962
O90.1 Disruption of perineal obstetric wound	0.037	0.962
O90.0 Disruption of Caesarean section wound	0.037	0.962
O88.8 Other obstetric embolism	0.037	0.962
O88.3 Obstetric pyaemic and septic embolism	0.037	0.962
O88.2 Obstetric blood-clot embolism	0.037	0.962
O88.1 Amniotic fluid embolism	0.037	0.962
O88.0 Obstetric air embolism	0.037	0.962
O89.9 Complication of anaesthesia during the puerperium, unspecified	0.037	0.962
O89.8 Other complications of anaesthesia during the puerperium	0.037	0.962
O89.6 Failed or difficult intubation during the puerperium	0.037	0.962
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium	0.037	0.962
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium	0.037	0.962
O89.3 Toxic reaction to local anaesthesia during the puerperium	0.037	0.962
O89.2 Central nervous system complications of anaesthesia during the puerperium	0.037	0.962
O89.1 Cardiac complications of anaesthesia during the puerperium	0.037	0.962
O89.0 Pulmonary complications of anaesthesia during the puerperium	0.037	0.962
O91.2 Nonpurulent mastitis associated with childbirth	0.037	0.962
O91.1 Abscess of breast associated with childbirth	0.037	0.962
O91.0 Infection of nipple associated with childbirth	0.037	0.962
O92.7 Other and unspecified disorders of lactation	0.037	0.962
O92.6 Galactorrhoea	0.037	0.962
O92.5 Suppressed lactation	0.037	0.962
O92.4 Hypogalactia	0.037	0.962
O92.3 Agalactia	0.037	0.962
O92.2 Other and unspecified disorders of breast associated with childbirth	0.037	0.962
O92.1 Cracked nipple associated with childbirth	0.037	0.962
O92.0 Retracted nipple associated with childbirth	0.037	0.962
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.037	0.963
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.037	0.963
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.037	0.963
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.037	0.963
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.037	0.963
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.037	0.963
O12.2 Gestational oedema with proteinuria	0.037	0.963
O12.1 Gestational proteinuria	0.037	0.963
O12.0 Gestational oedema	0.037	0.963
O15.9 Eclampsia, unspecified as to time period	0.037	0.963
O15.2 Eclampsia in the puerperium	0.037	0.963
O15.1 Eclampsia in labour	0.037	0.963
O15.0 Eclampsia in pregnancy	0.037	0.963
O01.9 Hydatidiform mole, unspecified	0.037	0.963
O01.1 Incomplete and partial hydatidiform mole	0.037	0.963
O01.0 Classical hydatidiform mole	0.037	0.963
O05.9 Complete or unspecified, without complication	0.037	0.963
O05.8 Complete or unspecified, with other and unspecified complications	0.037	0.963
O05.7 Complete or unspecified, complicated by embolism	0.037	0.963
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.037	0.963
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.037	0.963
O05.4 Incomplete, without complication	0.037	0.963
O05.3 Incomplete, with other and unspecified complications	0.037	0.963
O05.2 Incomplete, complicated by embolism	0.037	0.963
O05.1 Incomplete, complicated by delayed or excessive haemorrhage	0.037	0.963
O05.0 Incomplete, complicated by genital tract and pelvic infection	0.037	0.963
O06.9 Complete or unspecified, without complication	0.037	0.963
O06.8 Complete or unspecified, with other and unspecified complications	0.037	0.963
O06.7 Complete or unspecified, complicated by embolism	0.037	0.963
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.037	0.963
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.037	0.963
O06.4 Incomplete, without complication	0.037	0.963
O06.3 Incomplete, with other and unspecified complications	0.037	0.963
O06.2 Incomplete, complicated by embolism	0.037	0.963
O06.1 Incomplete, complicated by delayed or excessive haemorrhage	0.037	0.963
O06.0 Incomplete, complicated by genital tract and pelvic infection	0.037	0.963
O07.9 Other and unspecified failed attempted abortion, without complication	0.037	0.963
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications	0.037	0.963
O07.7 Other and unspecified failed attempted abortion, complicated by embolism	0.037	0.963
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage	0.037	0.963
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection	0.037	0.963
O07.4 Failed medical abortion, without complication	0.037	0.963
O07.3 Failed medical abortion, with other and unspecified complications	0.037	0.963
O07.2 Failed medical abortion, complicated by embolism	0.037	0.963
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage	0.037	0.963
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection	0.037	0.963
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified	0.037	0.963
O08.8 Other complications following abortion and ectopic and molar pregnancy	0.037	0.963
O08.7 Other venous complications following abortion and ectopic and molar pregnancy	0.037	0.963
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy	0.037	0.963
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy	0.037	0.963
O08.4 Renal failure following abortion and ectopic and molar pregnancy	0.037	0.963
O08.3 Shock following abortion and ectopic and molar pregnancy	0.037	0.963
O08.2 Embolism following abortion and ectopic and molar pregnancy	0.037	0.963
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy	0.037	0.963
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy	0.037	0.963
O82.9 Delivery by Caesarean section, unspecified	0.037	0.963
O82.8 Other single delivery by Caesarean section	0.037	0.963
O82.2 Delivery by Caesarean hysterectomy	0.037	0.963
O86.8 Other specified puerperal infections	0.036	0.963
O86.4 Pyrexia of unknown origin following delivery	0.036	0.963
O86.3 Other genito-urinary tract infections following delivery	0.036	0.963
O86.2 Urinary tract infection following delivery	0.036	0.963
O86.1 Other infection of genital tract following delivery	0.036	0.963
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.036	0.964
O34.8 Maternal care for other abnormalities of pelvic organs	0.036	0.964
O34.7 Maternal care for abnormality of vulva and perineum	0.036	0.964
O34.6 Maternal care for abnormality of vagina	0.036	0.964
O34.5 Maternal care for other abnormalities of gravid uterus	0.036	0.964
O34.3 Maternal care for cervical incompetence	0.036	0.964
O34.1 Maternal care for tumour of corpus uteri	0.036	0.964
O34.0 Maternal care for congenital malformation of uterus	0.036	0.964
O46.9 Antepartum haemorrhage, unspecified	0.036	0.964
O04 Medical abortion	0.035	0.964
O86.0 Infection of obstetric surgical wound	0.035	0.965
O32.1 Maternal care for breech presentation	0.035	0.965
O00.9 Ectopic pregnancy, unspecified	0.034	0.966
O00.8 Other ectopic pregnancy	0.034	0.966
O00.2 Ovarian pregnancy	0.034	0.966
O00.0 Abdominal pregnancy	0.034	0.966
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.032	0.967
Z37.0 Single live birth	0.032	0.968
O75.9 Complication of labour and delivery, unspecified	0.031	0.968
O75.5 Delayed delivery after artificial rupture of membranes	0.031	0.968
O75.4 Other complications of obstetric surgery and procedures	0.031	0.968
O75.3 Other infection during labour	0.031	0.968
O75.1 Shock during or following labour and delivery	0.031	0.968
O96.9 Death from unspecified obstetric cause	0.031	0.969
O96.1 Death from indirect obstetric cause	0.031	0.969
O96.0 Death from direct obstetric cause	0.031	0.969
O97.9 Death from sequelae of obstetric cause, unspecified	0.031	0.969
O97.1 Death from sequelae of indirect obstetric cause	0.031	0.969
O97.0 Death from sequelae of direct obstetric cause	0.031	0.969
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.031	0.969
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.031	0.969
O75.0 Maternal distress during labour and delivery	0.031	0.969
O75.2 Pyrexia during labour, not elsewhere classified	0.031	0.969
O00.1 Tubal pregnancy	0.030	0.970
O02.1 Missed abortion	0.030	0.970
O80.0 Spontaneous vertex delivery	0.030	0.970
Z37 Outcome of delivery	0.030	0.970
Z35 Supervision of high-risk pregnancy	0.029	0.971
Z35.5 Supervision of elderly primigravida	0.029	0.971
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.029	0.971
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.028	0.971
Z36 Antenatal screening	0.029	0.971
O72.3 Postpartum coagulation defects	0.028	0.972
O26.8 Other specified pregnancy-related conditions	0.028	0.972
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.027	0.972
Z36.0 Antenatal screening for chromosomal anomalies	0.026	0.974
O04.4 Incomplete, without complication	0.026	0.974
O72.0 Third-stage haemorrhage	0.026	0.974
O04.8 Complete or unspecified, with other and unspecified complications	0.025	0.974
O04.7 Complete or unspecified, complicated by embolism	0.025	0.974
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.025	0.974
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.025	0.974
O04.3 Incomplete, with other and unspecified complications	0.025	0.974
O04.2 Incomplete, complicated by embolism	0.025	0.974

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations