TreeWAS – Variant ID: rs11107616

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z09.8 Follow-up examination after other treatment for other conditions	0.000	0.707	0.293
H66.9 Otitis media, unspecified	0.212	0.788	0.000
H66 Suppurative and unspecified otitis media	0.210	0.789	0.000
H65-H75 Diseases of middle ear and mastoid	0.207	0.793	0.000
H65 Nonsuppurative otitis media	0.205	0.795	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.201	0.799	0.000
H74 Other disorders of middle ear and mastoid	0.192	0.808	0.000
H66.3 Other chronic suppurative otitis media	0.174	0.826	0.000
H65.3 Chronic mucoid otitis media	0.170	0.830	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.169	0.830	0.000
H68 Eustachian salpingitis and obstruction	0.169	0.831	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.169	0.831	0.000
H65.0 Acute serous otitis media	0.164	0.836	0.000
H74.0 Tympanosclerosis	0.162	0.838	0.000
H73 Other disorders of tympanic membrane	0.161	0.839	0.000
H65.2 Chronic serous otitis media	0.160	0.840	0.000
H70 Mastoiditis and related conditions	0.158	0.841	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.156	0.844	0.000
H65.1 Other acute nonsuppurative otitis media	0.156	0.844	0.000
H66.0 Acute suppurative otitis media	0.154	0.846	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.150	0.850	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.149	0.851	0.000
H67 Otitis media in diseases classified elsewhere	0.149	0.851	0.000
H74.4 Polyp of middle ear	0.146	0.853	0.000
H72 Perforation of tympanic membrane	0.145	0.855	0.000
H68.1 Obstruction of Eustachian tube	0.142	0.858	0.000
H74.1 Adhesive middle ear disease	0.141	0.859	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.137	0.863	0.000
H66.4 Suppurative otitis media, unspecified	0.135	0.865	0.000
H71 Cholesteatoma of middle ear	0.132	0.868	0.000
H73.8 Other specified disorders of tympanic membrane	0.129	0.871	0.000
H70.9 Mastoiditis, unspecified	0.123	0.876	0.000
H68.0 Eustachian salpingitis	0.121	0.878	0.000
H73.1 Chronic myringitis	0.116	0.884	0.000
H73.0 Acute myringitis	0.116	0.884	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.114	0.885	0.000
H70.8 Other mastoiditis and related conditions	0.114	0.886	0.000
H70.2 Petrositis	0.114	0.886	0.000
H70.1 Chronic mastoiditis	0.114	0.886	0.000
H70.0 Acute mastoiditis	0.114	0.886	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.112	0.888	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.110	0.889	0.000
H72.1 Attic perforation of tympanic membrane	0.110	0.890	0.000
H69 Other disorders of Eustachian tube	0.109	0.891	0.000
H72.0 Central perforation of tympanic membrane	0.109	0.891	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.107	0.893	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.107	0.893	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.107	0.893	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.107	0.893	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.107	0.893	0.000
H72.2 Other marginal perforations of tympanic membrane	0.096	0.904	0.000
H65.4 Other chronic nonsuppurative otitis media	0.089	0.910	0.000
H72.8 Other perforations of tympanic membrane	0.088	0.912	0.000
H69.0 Patulous Eustachian tube	0.078	0.921	0.000
H69.8 Other specified disorders of Eustachian tube	0.077	0.923	0.000
H69.9 Eustachian tube disorder, unspecified	0.043	0.957	0.001
D61.9 Aplastic anaemia, unspecified	0.000	0.972	0.028
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.000	0.975	0.025
E78.5 Hyperlipidaemia, unspecified	0.000	0.976	0.024
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.977	0.023
Z09.4 Follow-up examination after treatment of fracture	0.000	0.982	0.018
Z09.3 Follow-up examination after psychotherapy	0.000	0.982	0.018
Z09.7 Follow-up examination after combined treatment for other conditions	0.000	0.983	0.017
Chapter VIII Diseases of the ear and mastoid process	0.017	0.983	0.000
Z09.1 Follow-up examination after radiotherapy for other conditions	0.000	0.983	0.016
M16.1 Other primary coxarthrosis	0.016	0.984	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.015	0.985	0.000
D61 Other aplastic anaemias	0.000	0.986	0.014
M18.1 Other primary arthrosis of first carpometacarpal joint	0.014	0.986	0.000
O42 Premature rupture of membranes	0.013	0.987	0.000
E21.0 Primary hyperparathyroidism	0.013	0.987	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.013	0.987	0.000
C45.0 Mesothelioma of pleura	0.013	0.987	0.000
E20-E35 Disorders of other endocrine glands	0.012	0.988	0.000
J31.0 Chronic rhinitis	0.000	0.988	0.012
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.012	0.988	0.000
E28 Ovarian dysfunction	0.011	0.989	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.011	0.989	0.000
O43 Placental disorders	0.011	0.989	0.000
E24 Cushing's syndrome	0.011	0.989	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.011	0.989	0.000
E23 Hypofunction and other disorders of pituitary gland	0.011	0.989	0.000
O43.8 Other placental disorders	0.011	0.989	0.000
E22 Hyperfunction of pituitary gland	0.011	0.989	0.000
C45.9 Mesothelioma, unspecified	0.011	0.989	0.000
M18 Arthrosis of first carpometacarpal joint	0.011	0.989	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.010	0.989	0.000
D61.8 Other specified aplastic anaemias	0.000	0.990	0.010
D61.3 Idiopathic aplastic anaemia	0.000	0.990	0.010
D61.2 Aplastic anaemia due to other external agents	0.000	0.990	0.010
D61.1 Drug-induced aplastic anaemia	0.000	0.990	0.010
D61.0 Constitutional aplastic anaemia	0.000	0.990	0.010
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.010	0.990	0.000
E21.3 Hyperparathyroidism, unspecified	0.010	0.990	0.000
E29 Testicular dysfunction	0.010	0.990	0.000
C45 Mesothelioma	0.010	0.990	0.000
E28.3 Primary ovarian failure	0.010	0.990	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.010	0.990	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.010	0.990	0.000
H80-H83 Diseases of inner ear	0.010	0.990	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.010	0.990	0.000
E26 Hyperaldosteronism	0.010	0.990	0.000
O31 Complications specific to multiple gestation	0.010	0.990	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.010	0.990	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.010	0.990	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.010	0.990	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.010	0.990	0.000
O60-O75 Complications of labour and delivery	0.010	0.990	0.000
O34.1 Maternal care for tumour of corpus uteri	0.010	0.990	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.009	0.991	0.000
E21.4 Other specified disorders of parathyroid gland	0.009	0.991	0.000
E21.2 Other hyperparathyroidism	0.009	0.991	0.000
E23.0 Hypopituitarism	0.009	0.991	0.000
E28.2 Polycystic ovarian syndrome	0.009	0.991	0.000
O30 Multiple gestation	0.009	0.991	0.000
E24.9 Cushing's syndrome, unspecified	0.009	0.991	0.000
E24.8 Other Cushing's syndrome	0.009	0.991	0.000
O46.9 Antepartum haemorrhage, unspecified	0.009	0.991	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.009	0.991	0.000
E32 Diseases of thymus	0.009	0.991	0.000
E31 Polyglandular dysfunction	0.009	0.991	0.000
E30 Disorders of puberty, not elsewhere classified	0.009	0.991	0.000
E25 Adrenogenital disorders	0.009	0.991	0.000
O33 Maternal care for known or suspected disproportion	0.009	0.991	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.009	0.991	0.000
O43.0 Placental transfusion syndromes	0.009	0.991	0.000
O66 Other obstructed labour	0.009	0.991	0.000
O34.3 Maternal care for cervical incompetence	0.009	0.991	0.000
O41 Other disorders of amniotic fluid and membranes	0.009	0.991	0.000
E23.7 Disorder of pituitary gland, unspecified	0.009	0.991	0.000
E29.1 Testicular hypofunction	0.009	0.991	0.000
O46.8 Other antepartum haemorrhage	0.009	0.991	0.000
E22.1 Hyperprolactinaemia	0.009	0.991	0.000
E24.0 Pituitary-dependent Cushing's disease	0.009	0.991	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.009	0.991	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.008	0.991	0.000
O45 Premature separation of placenta [abruptio placentae]	0.008	0.991	0.000
E23.2 Diabetes insipidus	0.008	0.992	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.008	0.992	0.000
O34.0 Maternal care for congenital malformation of uterus	0.008	0.992	0.000
E34 Other endocrine disorders	0.008	0.992	0.000
E28.9 Ovarian dysfunction, unspecified	0.008	0.992	0.000
E28.8 Other ovarian dysfunction	0.008	0.992	0.000
E28.1 Androgen excess	0.008	0.992	0.000
E28.0 Oestrogen excess	0.008	0.992	0.000
E20 Hypoparathyroidism	0.008	0.992	0.000
E22.0 Acromegaly and pituitary gigantism	0.008	0.992	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.008	0.992	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.008	0.992	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O44 Placenta praevia	0.008	0.992	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.008	0.992	0.000
O42.9 Premature rupture of membranes, unspecified	0.008	0.992	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.008	0.992	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.008	0.992	0.000
E24.3 Ectopic ACTH syndrome	0.008	0.992	0.000
E24.1 Nelson's syndrome	0.008	0.992	0.000
O43.9 Placental disorder, unspecified	0.008	0.992	0.000
O43.2 Morbidly adherent placenta	0.008	0.992	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.008	0.992	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.008	0.992	0.000
O34.6 Maternal care for abnormality of vagina	0.008	0.992	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.008	0.992	0.000
E26.0 Primary hyperaldosteronism	0.008	0.992	0.000
E24.2 Drug-induced Cushing's syndrome	0.008	0.992	0.000
O24.4 Diabetes mellitus arising in pregnancy	0.008	0.992	0.000
O34.4 Maternal care for other abnormalities of cervix	0.008	0.992	0.000
O31.8 Other complications specific to multiple gestation	0.008	0.992	0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.008	0.992	0.000
E23.1 Drug-induced hypopituitarism	0.008	0.992	0.000
O75.3 Other infection during labour	0.008	0.992	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.008	0.992	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.008	0.992	0.000
E22.8 Other hyperfunction of pituitary gland	0.008	0.992	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.008	0.992	0.000
H60-H62 Diseases of external ear	0.008	0.992	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.008	0.992	0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.008	0.992	0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.008	0.992	0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.008	0.992	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.008	0.992	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.008	0.992	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.008	0.992	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.008	0.992	0.000
E29.9 Testicular dysfunction, unspecified	0.007	0.992	0.000
E29.8 Other testicular dysfunction	0.007	0.992	0.000
E29.0 Testicular hyperfunction	0.007	0.992	0.000
C45.2 Mesothelioma of pericardium	0.007	0.992	0.000
C45.1 Mesothelioma of peritoneum	0.007	0.992	0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.008	0.992	0.000
O24 Diabetes mellitus in pregnancy	0.008	0.992	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.007	0.993	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.007	0.993	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.007	0.993	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.007	0.993	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.007	0.993	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.007	0.993	0.000
O64.1 Obstructed labour due to breech presentation	0.007	0.993	0.000
O69 Labour and delivery complicated by umbilical cord complications	0.007	0.993	0.000
O85-O92 Complications predominantly related to the puerperium	0.007	0.993	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.007	0.993	0.000
O30.0 Twin pregnancy	0.007	0.993	0.000
O66.4 Failed trial of labour, unspecified	0.007	0.993	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.007	0.993	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.007	0.993	0.000
O73 Retained placenta and membranes, without haemorrhage	0.007	0.993	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.007	0.993	0.000
O31.0 Papyraceous foetus	0.007	0.993	0.000
E26.9 Hyperaldosteronism, unspecified	0.007	0.993	0.000
E26.8 Other hyperaldosteronism	0.007	0.993	0.000
E26.1 Secondary hyperaldosteronism	0.007	0.993	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.007	0.993	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.007	0.993	0.000
H80 Otosclerosis	0.007	0.993	0.000
O62 Abnormalities of forces of labour	0.007	0.993	0.000
O97 Death from sequelae of direct obstetric causes	0.007	0.993	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.007	0.993	0.000
O95 Obstetric death of unspecified cause	0.007	0.993	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.007	0.993	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.007	0.993	0.000
O33.9 Maternal care for disproportion, unspecified	0.007	0.993	0.000
M16 Coxarthrosis [arthrosis of hip]	0.007	0.993	0.000
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O74 Complications of anaesthesia during labour and delivery	0.007	0.993	0.000
O60 Preterm delivery	0.007	0.993	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
O70.1 Second degree perineal laceration during delivery	0.007	0.993	0.000
O14.1 Severe preeclampsia	0.007	0.993	0.000
O43.1 Malformation of placenta	0.007	0.993	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.007	0.993	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
O30.9 Multiple gestation, unspecified	0.007	0.993	0.000
O30.8 Other multiple gestation	0.007	0.993	0.000
O30.2 Quadruplet pregnancy	0.007	0.993	0.000
O30.1 Triplet pregnancy	0.007	0.993	0.000
O61 Failed induction of labour	0.007	0.993	0.000
O70 Perineal laceration during delivery	0.007	0.993	0.000
O32.2 Maternal care for transverse and oblique lie	0.007	0.993	0.000
O62.0 Primary inadequate contractions	0.007	0.993	0.000
O33.8 Maternal care for disproportion of other origin	0.007	0.993	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.007	0.993	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.007	0.993	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.007	0.993	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.007	0.993	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.007	0.993	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.007	0.993	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.007	0.993	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.007	0.993	0.000
O16 Unspecified maternal hypertension	0.007	0.993	0.000
E25.9 Adrenogenital disorder, unspecified	0.007	0.993	0.000
E25.8 Other adrenogenital disorders	0.007	0.993	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.007	0.993	0.000
E30.9 Disorder of puberty, unspecified	0.007	0.993	0.000
E30.8 Other disorders of puberty	0.007	0.993	0.000
E30.1 Precocious puberty	0.007	0.993	0.000
E30.0 Delayed puberty	0.007	0.993	0.000
E31.9 Polyglandular dysfunction, unspecified	0.007	0.993	0.000
E31.8 Other polyglandular dysfunction	0.007	0.993	0.000
E31.1 Polyglandular hyperfunction	0.007	0.993	0.000
E31.0 Autoimmune polyglandular failure	0.007	0.993	0.000
E32.9 Disease of thymus, unspecified	0.007	0.993	0.000
E32.8 Other diseases of thymus	0.007	0.993	0.000
E32.1 Abscess of thymus	0.007	0.993	0.000
E32.0 Persistent hyperplasia of thymus	0.007	0.993	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.007	0.993	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.007	0.993	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.007	0.993	0.000
O75.9 Complication of labour and delivery, unspecified	0.007	0.993	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.007	0.993	0.000
O75.4 Other complications of obstetric surgery and procedures	0.007	0.993	0.000
O75.1 Shock during or following labour and delivery	0.007	0.993	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.007	0.993	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.007	0.993	0.000
O66.9 Obstructed labour, unspecified	0.007	0.993	0.000
O66.8 Other specified obstructed labour	0.007	0.993	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.007	0.993	0.000
O66.2 Obstructed labour due to unusually large foetus	0.007	0.993	0.000
O66.1 Obstructed labour due to locked twins	0.007	0.993	0.000
H81 Disorders of vestibular function	0.007	0.993	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.007	0.993	0.000
O41.1 Infection of amniotic sac and membranes	0.007	0.993	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.993	0.007
C45.7 Mesothelioma of other sites	0.006	0.993	0.000
O71 Other obstetric trauma	0.007	0.993	0.000
O41.0 Oligohydramnios	0.006	0.993	0.000
O44.0 Placenta praevia specified as without haemorrhage	0.006	0.993	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.006	0.993	0.000
H81.0 Meniere's disease	0.007	0.993	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.006	0.993	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.006	0.994	0.000
O12.1 Gestational proteinuria	0.006	0.994	0.000
O15 Eclampsia	0.006	0.994	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.006	0.994	0.000
O14.9 Preeclampsia, unspecified	0.006	0.994	0.000
O45.8 Other premature separation of placenta	0.006	0.994	0.000
O45.0 Premature separation of placenta with coagulation defect	0.006	0.994	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.994	0.006
O69.9 Labour and delivery complicated by cord complication, unspecified	0.006	0.994	0.000
E34.5 Androgen resistance syndrome	0.006	0.994	0.000
E34.4 Constitutional tall stature	0.006	0.994	0.000
E34.3 Short stature, not elsewhere classified	0.006	0.994	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.006	0.994	0.000
E34.1 Other hypersecretion of intestinal hormones	0.006	0.994	0.000
E34.0 Carcinoid syndrome	0.006	0.994	0.000
E20.8 Other hypoparathyroidism	0.006	0.994	0.000
E20.1 Pseudohypoparathyroidism	0.006	0.994	0.000
E20.0 Idiopathic hypoparathyroidism	0.006	0.994	0.000
E27 Other disorders of adrenal gland	0.006	0.994	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.006	0.994	0.000
O64.5 Obstructed labour due to compound presentation	0.006	0.994	0.000
O64.4 Obstructed labour due to shoulder presentation	0.006	0.994	0.000
O64.3 Obstructed labour due to brow presentation	0.006	0.994	0.000
O64.2 Obstructed labour due to face presentation	0.006	0.994	0.000
O92 Other disorders of breast and lactation associated with childbirth	0.006	0.994	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.006	0.994	0.000
O12.2 Gestational oedema with proteinuria	0.006	0.994	0.000
O45.9 Premature separation of placenta, unspecified	0.006	0.994	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.006	0.994	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.006	0.994	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.006	0.994	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.006	0.994	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.006	0.994	0.000
O65.0 Obstructed labour due to deformed pelvis	0.006	0.994	0.000
E34.8 Other specified endocrine disorders	0.006	0.994	0.000
O75.8 Other specified complications of labour and delivery	0.006	0.994	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.006	0.994	0.000
O73.0 Retained placenta, without haemorrhage	0.006	0.994	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O64.8 Obstructed labour due to other malposition and malpresentation	0.006	0.994	0.000
O32.8 Maternal care for other malpresentation of foetus	0.006	0.994	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.006	0.994	0.000
O69.8 Labour and delivery complicated by other cord complications	0.006	0.994	0.000
O40 Polyhydramnios	0.006	0.994	0.000
O14.0 Moderate preeclampsia	0.006	0.994	0.000
O67.8 Other intrapartum haemorrhage	0.006	0.994	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.006	0.994	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.006	0.994	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O14.2 HELLP syndrome	0.006	0.994	0.000
H83 Other diseases of inner ear	0.006	0.994	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.006	0.994	0.000
T84.0 Mechanical complication of internal joint prosthesis	0.000	0.994	0.006
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.006	0.994	0.000
E34.9 Endocrine disorder, unspecified	0.006	0.994	0.000
O91 Infections of breast associated with childbirth	0.006	0.994	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.994	0.006
O69.1 Labour and delivery complicated by cord around neck, with compression	0.006	0.994	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.994	0.006
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.006	0.994	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.006	0.994	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.006	0.994	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.006	0.994	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.006	0.994	0.000
O22 Venous complications in pregnancy	0.006	0.994	0.000
O69.5 Labour and delivery complicated by vascular lesion of cord	0.005	0.994	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.005	0.994	0.000
O69.3 Labour and delivery complicated by short cord	0.005	0.994	0.000
E20.9 Hypoparathyroidism, unspecified	0.005	0.994	0.000
O92.2 Other and unspecified disorders of breast associated with childbirth	0.005	0.994	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.006	0.994	0.000
O89 Complications of anaesthesia during the puerperium	0.005	0.994	0.000
O88 Obstetric embolism	0.005	0.994	0.000
O85 Puerperal sepsis	0.005	0.994	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.006	0.994	0.000
O90 Complications of the puerperium, not elsewhere classified	0.005	0.994	0.000
H35.4 Peripheral retinal degeneration	0.006	0.994	0.000
O23 Infections of genito-urinary tract in pregnancy	0.005	0.994	0.000
M15-M19 Arthrosis	0.006	0.994	0.000
H80.8 Other otosclerosis	0.005	0.995	0.000
H80.2 Cochlear otosclerosis	0.005	0.995	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.005	0.995	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.005	0.995	0.000
O62.9 Abnormality of forces of labour, unspecified	0.005	0.995	0.000
O62.8 Other abnormalities of forces of labour	0.005	0.995	0.000
O62.1 Secondary uterine inertia	0.005	0.995	0.000
O96.9 Death from unspecified obstetric cause	0.005	0.995	0.000
O96.1 Death from indirect obstetric cause	0.005	0.995	0.000
O96.0 Death from direct obstetric cause	0.005	0.995	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.005	0.995	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.005	0.995	0.000
O97.0 Death from sequelae of direct obstetric cause	0.005	0.995	0.000
O29 Complications of anaesthesia during pregnancy	0.005	0.995	0.000
O25 Malnutrition in pregnancy	0.005	0.995	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.995	0.005
O32.6 Maternal care for compound presentation	0.005	0.995	0.000
O70.2 Third degree perineal laceration during delivery	0.005	0.995	0.000
M16.4 Posttraumatic coxarthrosis, bilateral	0.005	0.995	0.000
O44.1 Placenta praevia with haemorrhage	0.005	0.995	0.000
O60.3 Preterm delivery without spontaneous labour	0.005	0.995	0.000
O60.2 Preterm spontaneous labour with term delivery	0.005	0.995	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.005	0.995	0.000
O60.0 Preterm labour without delivery	0.005	0.995	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.005	0.995	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.005	0.995	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.005	0.995	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.005	0.995	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.005	0.995	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.005	0.995	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.005	0.995	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.005	0.995	0.000
K35.9 Acute appendicitis, unspecified	0.005	0.995	0.000
H80.9 Otosclerosis, unspecified	0.005	0.995	0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.000	0.995	0.005
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O87 Venous complications in the puerperium	0.005	0.995	0.000
H81.8 Other disorders of vestibular function	0.005	0.995	0.000
O28 Abnormal findings on antenatal screening of mother	0.005	0.995	0.000
J06.9 Acute upper respiratory infection, unspecified	0.000	0.995	0.005
O61.9 Failed induction of labour, unspecified	0.005	0.995	0.000
O61.8 Other failed induction of labour	0.005	0.995	0.000
O61.1 Failed instrumental induction of labour	0.005	0.995	0.000
O70.3 Fourth degree perineal laceration during delivery	0.005	0.995	0.000
M16.3 Other dysplastic coxarthrosis	0.005	0.995	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.005	0.995	0.000
O71.7 Obstetric haematoma of pelvis	0.005	0.995	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.005	0.995	0.000
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.005	0.995	0.000
E78.6 Lipoprotein deficiency	0.000	0.995	0.005
E78.3 Hyperchylomicronaemia	0.000	0.995	0.005
E78.2 Mixed hyperlipidaemia	0.000	0.995	0.005
H81.4 Vertigo of central origin	0.005	0.995	0.000
H81.3 Other peripheral vertigo	0.005	0.995	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.005	0.995	0.000
O32.4 Maternal care for high head at term	0.005	0.995	0.000
O86 Other puerperal infections	0.005	0.995	0.000
M16.7 Other secondary coxarthrosis	0.005	0.995	0.000
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O71.9 Obstetric trauma, unspecified	0.005	0.995	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.005	0.995	0.000
O71.5 Other obstetric injury to pelvic organs	0.005	0.995	0.000
O71.3 Obstetric laceration of cervix	0.005	0.995	0.000
O71.2 Postpartum inversion of uterus	0.005	0.995	0.000
O71.1 Rupture of uterus during labour	0.005	0.995	0.000
O71.0 Rupture of uterus before onset of labour	0.005	0.995	0.000
O80-O84 Delivery	0.005	0.995	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.005	0.995	0.000
M16.5 Other posttraumatic coxarthrosis	0.005	0.995	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
O21 Excessive vomiting in pregnancy	0.005	0.995	0.000
O71.8 Other specified obstetric trauma	0.005	0.995	0.000
O61.0 Failed medical induction of labour	0.005	0.995	0.000
O15.9 Eclampsia, unspecified as to time period	0.005	0.995	0.000
O15.2 Eclampsia in the puerperium	0.005	0.995	0.000
O15.1 Eclampsia in labour	0.005	0.995	0.000
O15.0 Eclampsia in pregnancy	0.005	0.995	0.000
S32.50 Fracture of pubis (closed)	0.000	0.995	0.005
N83.0 Follicular cyst of ovary	0.000	0.995	0.005
E27.5 Adrenomedullary hyperfunction	0.005	0.995	0.000
E27.0 Other adrenocortical overactivity	0.005	0.995	0.000
E78.4 Other hyperlipidaemia	0.000	0.995	0.005
E27.2 Addisonian crisis	0.005	0.995	0.000
O92.7 Other and unspecified disorders of lactation	0.005	0.995	0.000
O92.6 Galactorrhoea	0.005	0.995	0.000
O92.5 Suppressed lactation	0.005	0.995	0.000
O92.4 Hypogalactia	0.005	0.995	0.000
O92.3 Agalactia	0.005	0.995	0.000
O92.0 Retracted nipple associated with childbirth	0.005	0.995	0.000
O75.0 Maternal distress during labour and delivery	0.004	0.995	0.000
O00-O08 Pregnancy with abortive outcome	0.005	0.995	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.005	0.995	0.000
K63.9 Disease of intestine, unspecified	0.000	0.995	0.005
M16.0 Primary coxarthrosis, bilateral	0.005	0.995	0.000
L93.0 Discoid lupus erythematosus	0.005	0.995	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.995	0.005
O69.2 Labour and delivery complicated by other cord entanglement	0.005	0.995	0.000
E27.8 Other specified disorders of adrenal gland	0.005	0.995	0.000
O23.5 Infections of the genital tract in pregnancy	0.005	0.995	0.000
O91.1 Abscess of breast associated with childbirth	0.004	0.995	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.005	0.995	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.004	0.995	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.004	0.995	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
H62.2 Otitis externa in mycoses	0.004	0.995	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.004	0.995	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.004	0.995	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.004	0.995	0.000
O92.1 Cracked nipple associated with childbirth	0.004	0.995	0.000
O20 Haemorrhage in early pregnancy	0.005	0.995	0.000
O90.2 Haematoma of obstetric wound	0.004	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations