TreeWAS – Variant ID: rs11109142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I50.1 Left ventricular failure	0.014	0.986	0.000
I45.1 Other and unspecified right bundle-branch block	0.014	0.986	0.000
I45 Other conduction disorders	0.013	0.987	0.000
I50 Heart failure	0.013	0.987	0.000
I44 Atrioventricular and left bundle-branch block	0.013	0.987	0.000
I50.0 Congestive heart failure	0.012	0.988	0.000
I44.2 Atrioventricular block, complete	0.012	0.988	0.000
I44.0 Atrioventricular block, first degree	0.012	0.988	0.000
I45.2 Bifascicular block	0.012	0.988	0.000
I45.3 Trifascicular block	0.011	0.989	0.000
I30-I52 Other forms of heart disease	0.011	0.989	0.000
I44.1 Atrioventricular block, second degree	0.011	0.989	0.000
I45.9 Conduction disorder, unspecified	0.011	0.989	0.000
I44.6 Other and unspecified fascicular block	0.010	0.990	0.000
I45.8 Other specified conduction disorders	0.010	0.990	0.000
I45.5 Other specified heart block	0.010	0.990	0.000
I45.4 Nonspecific intraventricular block	0.010	0.990	0.000
I45.0 Right fascicular block	0.010	0.990	0.000
I44.5 Left posterior fascicular block	0.009	0.990	0.000
I44.4 Left anterior fascicular block	0.009	0.990	0.000
I33 Acute and subacute endocarditis	0.009	0.991	0.000
I44.3 Other and unspecified atrioventricular block	0.009	0.991	0.000
I44.7 Left bundle-branch block, unspecified	0.009	0.991	0.000
I47 Paroxysmal tachycardia	0.009	0.991	0.000
I30 Acute pericarditis	0.009	0.991	0.000
I37 Pulmonary valve disorders	0.008	0.991	0.000
I45.6 Preexcitation syndrome	0.008	0.992	0.000
I34 Nonrheumatic mitral valve disorders	0.008	0.992	0.000
I42 Cardiomyopathy	0.008	0.992	0.000
I52 Other heart disorders in diseases classified elsewhere	0.008	0.992	0.000
I48 Atrial fibrillation and flutter	0.008	0.992	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.008	0.992	0.000
I41 Myocarditis in diseases classified elsewhere	0.008	0.992	0.000
I40 Acute myocarditis	0.008	0.992	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.008	0.992	0.000
I36 Nonrheumatic tricuspid valve disorders	0.008	0.992	0.000
I32 Pericarditis in diseases classified elsewhere	0.008	0.992	0.000
I31 Other diseases of pericardium	0.008	0.992	0.000
I47.0 Reentry ventricular arrhythmia	0.008	0.992	0.000
K59.0 Constipation	0.000	0.992	0.008
I33.0 Acute and subacute infective endocarditis	0.008	0.992	0.000
I42.0 Dilated cardiomyopathy	0.007	0.993	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.007	0.993	0.000
I30.9 Acute pericarditis, unspecified	0.007	0.993	0.000
I33.9 Acute endocarditis, unspecified	0.007	0.993	0.000
I37.1 Pulmonary valve insufficiency	0.007	0.993	0.000
I34.1 Mitral (valve) prolapse	0.007	0.993	0.000
I47.9 Paroxysmal tachycardia, unspecified	0.006	0.993	0.000
I35 Nonrheumatic aortic valve disorders	0.006	0.993	0.000
I30.8 Other forms of acute pericarditis	0.006	0.993	0.000
I30.1 Infective pericarditis	0.006	0.993	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.006	0.993	0.000
I42.2 Other hypertrophic cardiomyopathy	0.006	0.993	0.000
Y43.3 Other antineoplastic drugs	0.000	0.993	0.007
I37.9 Pulmonary valve disorder, unspecified	0.006	0.994	0.000
I37.8 Other pulmonary valve disorders	0.006	0.994	0.000
I37.2 Pulmonary valve stenosis with insufficiency	0.006	0.994	0.000
I37.0 Pulmonary valve stenosis	0.006	0.994	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.006	0.994	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.006	0.994	0.000
I42.8 Other cardiomyopathies	0.006	0.994	0.000
I42.7 Cardiomyopathy due to drugs and other external agents	0.006	0.994	0.000
I42.6 Alcoholic cardiomyopathy	0.006	0.994	0.000
I42.5 Other restrictive cardiomyopathy	0.006	0.994	0.000
I42.4 Endocardial fibroelastosis	0.006	0.994	0.000
I42.3 Endomyocardial (eosinophilic) disease	0.006	0.994	0.000
I32.8 Pericarditis in other diseases classified elsewhere	0.006	0.994	0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified	0.006	0.994	0.000
I36.8 Other nonrheumatic tricuspid valve disorders	0.006	0.994	0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency	0.006	0.994	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.006	0.994	0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis	0.006	0.994	0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere	0.006	0.994	0.000
I39.4 Multiple valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.1 Aortic valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I39.0 Mitral valve disorders in diseases classified elsewhere	0.006	0.994	0.000
I40.9 Acute myocarditis, unspecified	0.006	0.994	0.000
I40.8 Other acute myocarditis	0.006	0.994	0.000
I40.1 Isolated myocarditis	0.006	0.994	0.000
I40.0 Infective myocarditis	0.006	0.994	0.000
I41.8 Myocarditis in other diseases classified elsewhere	0.006	0.994	0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I41.1 Myocarditis in viral diseases classified elsewhere	0.006	0.994	0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere	0.006	0.994	0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere	0.006	0.994	0.000
I43.2 Cardiomyopathy in nutritional diseases	0.006	0.994	0.000
I43.1 Cardiomyopathy in metabolic diseases	0.006	0.994	0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified	0.006	0.994	0.000
I48.4 Atypical atrial flutter	0.006	0.994	0.000
I48.3 Typical atrial flutter	0.006	0.994	0.000
I48.2 Chronic atrial fibrillation	0.006	0.994	0.000
I48.1 Persistent atrial fibrillation	0.006	0.994	0.000
I48.0 Paroxysmal atrial fibrillation	0.006	0.994	0.000
I52.8 Other heart disorders in other diseases classified elsewhere	0.006	0.994	0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere	0.006	0.994	0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere	0.006	0.994	0.000
I31.9 Disease of pericardium, unspecified	0.006	0.994	0.000
I31.8 Other specified diseases of pericardium	0.006	0.994	0.000
I31.2 Haemopericardium, not elsewhere classified	0.006	0.994	0.000
I31.1 Chronic constrictive pericarditis	0.006	0.994	0.000
I31.0 Chronic adhesive pericarditis	0.006	0.994	0.000
I42.1 Obstructive hypertrophic cardiomyopathy	0.006	0.994	0.000
I47.2 Ventricular tachycardia	0.006	0.994	0.000
I38 Endocarditis, valve unspecified	0.006	0.994	0.000
I50.9 Heart failure, unspecified	0.006	0.994	0.000
I47.1 Supraventricular tachycardia	0.006	0.994	0.000
I31.3 Pericardial effusion (noninflammatory)	0.005	0.994	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.005	0.995	0.000
I35.9 Aortic valve disorder, unspecified	0.005	0.995	0.000
Z13.9 Special screening examination, unspecified	0.000	0.995	0.005
I46 Cardiac arrest	0.005	0.995	0.000
I35.8 Other aortic valve disorders	0.005	0.995	0.000
N50.8 Other specified disorders of male genital organs	0.000	0.995	0.005
I35.1 Aortic (valve) insufficiency	0.005	0.995	0.000
I34.0 Mitral (valve) insufficiency	0.005	0.995	0.000
Z80.3 Family history of malignant neoplasm of breast	0.004	0.996	0.000
I42.9 Cardiomyopathy, unspecified	0.004	0.996	0.000
F41.9 Anxiety disorder, unspecified	0.000	0.996	0.004
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.996	0.004
I46.1 Sudden cardiac death, so described	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
Y43 Primarily systemic agents	0.000	0.996	0.004
J98.1 Pulmonary collapse	0.000	0.997	0.003
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C43.5 Malignant melanoma of trunk	0.000	0.997	0.003
K52.9 Non-infective gastro-enteritis and colitis, unspecified	0.000	0.997	0.003
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
Y43.9 Primarily systemic agent, unspecified	0.000	0.997	0.003
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.997	0.003
Y43.6 Enzymes, not elsewhere classified	0.000	0.997	0.003
Y43.5 Acidifying and alkalising agents	0.000	0.997	0.003
Y43.4 Immunosuppressive agents	0.000	0.997	0.003
Y43.2 Antineoplastic natural products	0.000	0.997	0.003
Y43.1 Antineoplastic antimetabolites	0.000	0.997	0.003
Y43.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
I46.9 Cardiac arrest, unspecified	0.002	0.997	0.001
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
C43 Malignant melanoma of skin	0.000	0.997	0.003
J98.4 Other disorders of lung	0.000	0.997	0.003
J98 Other respiratory disorders	0.000	0.997	0.003
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I51 Complications and ill-defined descriptions of heart disease	0.003	0.997	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
I46.0 Cardiac arrest with successful resuscitation	0.002	0.997	0.001
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.997	0.003
K70.9 Alcoholic liver disease, unspecified	0.000	0.997	0.003
Z80.4 Family history of malignant neoplasm of genital organs	0.002	0.997	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.997	0.002
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.998	0.002
N85.0 Endometrial glandular hyperplasia	0.000	0.998	0.002
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.002
C43.8 Overlapping malignant melanoma of skin	0.000	0.998	0.002
C43.4 Malignant melanoma of scalp and neck	0.000	0.998	0.002
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.998	0.002
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.998	0.002
C43.0 Malignant melanoma of lip	0.000	0.998	0.002
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.998	0.002
J98.9 Respiratory disorder, unspecified	0.000	0.998	0.002
J98.6 Disorders of diaphragm	0.000	0.998	0.002
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.998	0.002
J98.3 Compensatory emphysema	0.000	0.998	0.002
J98.2 Interstitial emphysema	0.000	0.998	0.002
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
I49.1 Atrial premature depolarisation	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
J98.8 Other specified respiratory disorders	0.000	0.998	0.002
F41 Other anxiety disorders	0.000	0.998	0.002
Z80 Family history of malignant neoplasm	0.002	0.998	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.002	0.998	0.000
I51.6 Cardiovascular disease, unspecified	0.002	0.998	0.000
I51.5 Myocardial degeneration	0.002	0.998	0.000
I51.4 Myocarditis, unspecified	0.002	0.998	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.002	0.998	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.002	0.998	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.002	0.998	0.000
I51.0 Cardiac septal defect, acquired	0.002	0.998	0.000
K59 Other functional intestinal disorders	0.000	0.998	0.002
N93.0 Postcoital and contact bleeding	0.002	0.998	0.000
Z80.6 Family history of leukaemia	0.002	0.998	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.998	0.002
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.002	0.998	0.000
I71 Aortic aneurysm and dissection	0.000	0.998	0.002
N50 Other disorders of male genital organs	0.000	0.998	0.002
M79.66 Pain in limb (Lower leg)	0.000	0.998	0.002
I49.3 Ventricular premature depolarisation	0.002	0.998	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.998	0.002
J34.2 Deviated nasal septum	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
Z80.8 Family history of malignant neoplasm of other organs or systems	0.002	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.998	0.002
T42.4 Benzodiazepines	0.002	0.998	0.000
F41.8 Other specified anxiety disorders	0.000	0.998	0.002
F41.3 Other mixed anxiety disorders	0.000	0.998	0.002
F41.1 Generalised anxiety disorder	0.000	0.998	0.002
I49.5 Sick sinus syndrome	0.002	0.998	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.000	0.998	0.002
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.002	0.998	0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.002	0.998	0.000
K70 Alcoholic liver disease	0.000	0.998	0.002
I35.0 Aortic (valve) stenosis	0.001	0.998	0.001
K59.4 Anal spasm	0.000	0.998	0.002
K59.2 Neurogenic bowel, not elsewhere classified	0.000	0.998	0.002
K59.1 Functional diarrhoea	0.000	0.998	0.002
J34.3 Hypertrophy of nasal turbinates	0.002	0.998	0.000
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.002	0.998	0.000
Y45.0 Opioids and related analgesics	0.000	0.998	0.002
J32.0 Chronic maxillary sinusitis	0.002	0.998	0.000
Z92.3 Personal history of irradiation	0.000	0.998	0.002
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.000	0.998	0.002
D12.6 Colon, unspecified	0.002	0.998	0.000
N50.9 Disorder of male genital organs, unspecified	0.000	0.998	0.002
N50.0 Atrophy of testis	0.000	0.998	0.002
E04.2 Non-toxic multinodular goitre	0.000	0.998	0.002
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.998	0.002
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.998	0.002
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.998	0.002
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.998	0.002
I71.0 Dissection of aorta [any part]	0.000	0.998	0.002
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.998	0.002
O94-O99 Other obstetric conditions, not elsewhere classified	0.002	0.998	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.000	0.998	0.002
K70.4 Alcoholic hepatic failure	0.000	0.998	0.001
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.998	0.001
K70.0 Alcoholic fatty liver	0.000	0.998	0.001
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
Y95 Nosocomial condition	0.000	0.998	0.002
K59.8 Other specified functional intestinal disorders	0.000	0.998	0.001
R29.6 Tendency to fall, not elsewhere classified	0.000	0.998	0.002
K59.9 Functional intestinal disorder, unspecified	0.000	0.998	0.001
N87.1 Moderate cervical dysplasia	0.002	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.001	0.998	0.000
H11.3 Conjunctival haemorrhage	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
I49.9 Cardiac arrhythmia, unspecified	0.001	0.998	0.000
I51.9 Heart disease, unspecified	0.001	0.998	0.001
N39.3 Stress incontinence	0.000	0.998	0.002
Y83.8 Other surgical procedures	0.000	0.998	0.002
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
I51.8 Other ill-defined heart diseases	0.001	0.998	0.000
K70.1 Alcoholic hepatitis	0.000	0.998	0.001
J34 Other disorders of nose and nasal sinuses	0.002	0.998	0.000
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.001
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.000	0.998	0.001
Y45.8 Other analgesics and antipyretics	0.000	0.998	0.001
Y45.5 4-Aminophenol derivatives	0.000	0.998	0.001
Y45.4 Antirheumatics	0.000	0.998	0.001
Y45.2 Propionic acid derivatives	0.000	0.998	0.001
Y45.1 Salicylates	0.000	0.998	0.001
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.998	0.000
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.001
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.998	0.001
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O97 Death from sequelae of direct obstetric causes	0.001	0.999	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.001	0.999	0.000
O95 Obstetric death of unspecified cause	0.001	0.999	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Y59 Other and unspecified vaccines and biological substances	0.000	0.999	0.001
Y58 Bacterial vaccines	0.000	0.999	0.001
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.999	0.001
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.999	0.001
Y53 Agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
Y50 Central nervous system stimulants, not elsewhere classified	0.000	0.999	0.001
Y49 Psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
Y48 Anaesthetics and therapeutic gases	0.000	0.999	0.001
Y47 Sedatives, hypnotics and antianxiety drugs	0.000	0.999	0.001
Y46 Antiepileptics and anti-Parkinsonism drugs	0.000	0.999	0.001
S72.00 Fracture of neck of femur (closed)	0.001	0.999	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.001	0.999	0.000
N93.8 Other specified abnormal uterine and vaginal bleeding	0.001	0.999	0.000
Y40 Systemic antibiotics	0.000	0.999	0.001
N50.1 Vascular disorders of male genital organs	0.000	0.999	0.001
D70 Agranulocytosis	0.000	0.999	0.001
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.001	0.999	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.000	0.999	0.001
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
O30.0 Twin pregnancy	0.001	0.999	0.000
S43.1 Dislocation of acromioclavicular joint	0.001	0.999	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.999	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.999	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.999	0.000
T42.3 Barbiturates	0.001	0.999	0.000
T42.2 Succinimides and oxazolidinediones	0.001	0.999	0.000
T42.1 Iminostilbenes	0.001	0.999	0.000
T42.0 Hydantoin derivatives	0.001	0.999	0.000
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
Y40.0 Penicillins	0.000	0.999	0.001
Y57.9 Drug or medicament, unspecified	0.000	0.999	0.001
F41.2 Mixed anxiety and depressive disorder	0.000	0.999	0.001
H11.1 Conjunctival degenerations and deposits	0.001	0.999	0.000
Y42.9 Other and unspecified hormone antagonists	0.000	0.999	0.001
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.999	0.001
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
Y42.4 Oral contraceptives	0.000	0.999	0.001
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
Y42.2 Antithyroid drugs	0.000	0.999	0.001
Y42.1 Thyroid hormones and substitutes	0.000	0.999	0.001
Y42.0 Glucocorticoids and synthetic analogs	0.000	0.999	0.001
S62.20 Fracture of first metacarpal bone (closed)	0.001	0.999	0.000
J34.0 Abscess, furuncle and carbuncle of nose	0.001	0.999	0.000
O96.9 Death from unspecified obstetric cause	0.001	0.999	0.000
O96.1 Death from indirect obstetric cause	0.001	0.999	0.000
O96.0 Death from direct obstetric cause	0.001	0.999	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.001	0.999	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.001	0.999	0.000
O97.0 Death from sequelae of direct obstetric cause	0.001	0.999	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
Y57.8 Other drugs and medicaments	0.000	0.999	0.001
Y57.7 Vitamins, not elsewhere classified	0.000	0.999	0.001
Y57.6 Other diagnostic agents	0.000	0.999	0.001
Y57.5 X-ray contrast media	0.000	0.999	0.001
Y57.4 Pharmaceutical excipients	0.000	0.999	0.001
Y57.3 Alcohol deterrents	0.000	0.999	0.001
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
Y57.1 Lipotropic drugs	0.000	0.999	0.001
Y57.0 Appetite depressants [anorectics]	0.000	0.999	0.001
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
D13.1 Stomach	0.001	0.999	0.000
Y46.8 Antispasticity drugs	0.000	0.999	0.001
Y46.7 Anti-Parkinsonism drugs	0.000	0.999	0.001
Y46.6 Other and unspecified antiepileptics	0.000	0.999	0.001
Y46.5 Valproic acid	0.000	0.999	0.001
Y46.4 Iminostilbenes	0.000	0.999	0.001
Y46.3 Deoxybarbiturates	0.000	0.999	0.001
Y46.2 Hydantoin derivatives	0.000	0.999	0.001
Y46.1 Oxazolidinediones	0.000	0.999	0.001
Y46.0 Succinimides	0.000	0.999	0.001
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.000	0.999	0.001
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.000	0.999	0.001
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.000	0.999	0.001
Y47.4 Bromine compounds	0.000	0.999	0.001
Y47.3 Paraldehyde	0.000	0.999	0.001
Y47.2 Chloral derivatives	0.000	0.999	0.001
Y47.1 Benzodiazepines	0.000	0.999	0.001
Y47.0 Barbiturates, not elsewhere classified	0.000	0.999	0.001
Y48.5 Therapeutic gases	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.000	0.999	0.001
Y48.3 Local anaesthetics	0.000	0.999	0.001
Y48.2 Other and unspecified general anaesthetics	0.000	0.999	0.001
Y48.1 Parenteral anaesthetics	0.000	0.999	0.001
Y48.0 Inhaled anaesthetics	0.000	0.999	0.001
Y49.9 Psychotropic drug, unspecified	0.000	0.999	0.001
Y49.8 Other psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
Y49.7 Psychostimulants with abuse potential	0.000	0.999	0.001
Y49.6 Psychodysleptics [hallucinogens]	0.000	0.999	0.001
Y49.5 Other antipsychotics and neuroleptics	0.000	0.999	0.001
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
Y49.2 Other and unspecified antidepressants	0.000	0.999	0.001
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.999	0.001
Y49.0 Tricyclic and tetracyclic antidepressants	0.000	0.999	0.001
Y50.9 Central nervous system stimulant, unspecified	0.000	0.999	0.001
Y50.8 Other central nervous system stimulants	0.000	0.999	0.001
Y50.2 Methylxanthines, not elsewhere classified	0.000	0.999	0.001
Y50.1 Opioid receptor antagonists	0.000	0.999	0.001
Y50.0 Analeptics	0.000	0.999	0.001
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.999	0.001
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
Y53.7 Emetics	0.000	0.999	0.001
Y53.6 Antidiarrhoeal drugs	0.000	0.999	0.001
Y53.5 Digestants	0.000	0.999	0.001
Y53.4 Other laxatives	0.000	0.999	0.001
Y53.3 Saline and osmotic laxatives	0.000	0.999	0.001
Y53.2 Stimulant laxatives	0.000	0.999	0.001
Y53.1 Other antacids and anti-gastric-secretion drugs	0.000	0.999	0.001
Y53.0 Histamine H2-receptor antagonists	0.000	0.999	0.001
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
Y55.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
Y55.5 Anticommon cold drugs	0.000	0.999	0.001
Y55.4 Expectorants	0.000	0.999	0.001
Y55.3 Antitussives	0.000	0.999	0.001
Y55.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.999	0.001
Y55.0 Oxytocic drugs	0.000	0.999	0.001
Y56.9 Topical agent, unspecified	0.000	0.999	0.001
Y56.8 Other topical agents	0.000	0.999	0.001
Y56.7 Dental drugs, topically applied	0.000	0.999	0.001
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.999	0.001
Y56.5 Ophthalmological drugs and preparations	0.000	0.999	0.001
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.999	0.001
Y56.3 Emollients, demulcents and protectants	0.000	0.999	0.001
Y56.2 Local astringents and local detergents	0.000	0.999	0.001
Y56.1 Antipruritics	0.000	0.999	0.001
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
Y58.9 Other and unspecified bacterial vaccines	0.000	0.999	0.001
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.000	0.999	0.001
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.000	0.999	0.001
Y58.5 Diphtheria vaccine	0.000	0.999	0.001
Y58.4 Tetanus vaccine	0.000	0.999	0.001
Y58.3 Plague vaccine	0.000	0.999	0.001
Y58.2 Cholera vaccine	0.000	0.999	0.001
Y58.1 Typhoid and paratyphoid vaccine	0.000	0.999	0.001
Y58.0 BCG vaccine	0.000	0.999	0.001
Y59.9 Vaccine or biological substance, unspecified	0.000	0.999	0.001
Y59.8 Other specified vaccines and biological substances	0.000	0.999	0.001
Y59.3 Immunoglobulin	0.000	0.999	0.001
Y59.2 Protozoal vaccines	0.000	0.999	0.001
Y59.1 Rickettsial vaccines	0.000	0.999	0.001
Y59.0 Viral vaccines	0.000	0.999	0.001
Z37.2 Twins, both liveborn	0.001	0.999	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.001	0.999	0.000
Y44 Agents primarily affecting blood constituents	0.000	0.999	0.001
L40.9 Psoriasis, unspecified	0.001	0.999	0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
D25.0 Submucous leiomyoma of uterus	0.000	0.999	0.001
H11.0 Pterygium	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.001	0.999	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.001	0.999	0.000
S43.4 Sprain and strain of shoulder joint	0.001	0.999	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.001	0.999	0.000
S43.2 Dislocation of sternoclavicular joint	0.001	0.999	0.000
S66.8 Injury of other muscles and tendons at wrist and hand level	0.001	0.999	0.000
Y40.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
Y40.8 Other systemic antibiotics	0.000	0.999	0.001
Y40.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
Y40.6 Rifamycins	0.000	0.999	0.001
Y40.5 Aminoglycosides	0.000	0.999	0.001
Y40.4 Tetracyclines	0.000	0.999	0.001
Y40.2 Chloramphenicol group	0.000	0.999	0.001
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.999	0.001
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.999	0.001
Y41.5 Antiviral drugs	0.000	0.999	0.001
Y41.4 Anthelminthics	0.000	0.999	0.001
Y41.3 Other antiprotozoal drugs	0.000	0.999	0.001
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.999	0.001
Y41.1 Antimycobacterial drugs	0.000	0.999	0.001
Y41.0 Sulphonamides	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.000	0.999	0.001
Y54.8 Agents affecting uric acid metabolism	0.000	0.999	0.001
Y54.7 Agents affecting calcification	0.000	0.999	0.001
Y54.6 Electrolytic, caloric and water-balance agents	0.000	0.999	0.001
Y54.5 Other diuretics	0.000	0.999	0.001
Y54.4 Loop [high-ceiling] diuretics	0.000	0.999	0.001
Y54.2 Carbonic-anhydrase inhibitors	0.000	0.999	0.001
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.000	0.999	0.001
Y54.0 Mineralocorticoids	0.000	0.999	0.001
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.999	0.001
S61.0 Open wound of finger(s) without damage to nail	0.001	0.999	0.000
H11 Other disorders of conjunctiva	0.001	0.999	0.000
S65.5 Injury of blood vessel(s) of other finger	0.001	0.999	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.999	0.001
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.999	0.001
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.999	0.001
S62.7 Multiple fractures of fingers	0.001	0.999	0.000
S72.0 Fracture of neck of femur	0.001	0.999	0.000
S61.7 Multiple open wounds of wrist and hand	0.001	0.999	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.001	0.999	0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.001	0.999	0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.001	0.999	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.001	0.999	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.001	0.999	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.999	0.001
Y44.9 Other and unspecified agents affecting blood constituents	0.000	0.999	0.001
Y44.7 Plasma substitutes	0.000	0.999	0.001
Y44.6 Natural blood and blood products	0.000	0.999	0.001
Y44.5 Thrombolytic drugs	0.000	0.999	0.001
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.000	0.999	0.001
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.999	0.001
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.000	0.999	0.001
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.000	0.999	0.001
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.999	0.001
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.999	0.001
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.999	0.001
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.999	0.001
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.999	0.001
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.999	0.001
Y51.0 Anticholinesterase agents	0.000	0.999	0.001
Y54.3 Benzothiadiazine derivatives	0.000	0.999	0.001
S65 Injury of blood vessels at wrist and hand level	0.001	0.999	0.000
S62.2 Fracture of first metacarpal bone	0.001	0.999	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.999	0.001
K76.6 Portal hypertension	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations