TreeWAS – Variant ID: rs11122834

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	No effect posterior probability	Protective posterior probability
M23 Internal derangement of knee	0.789	0.211
M20-M25 Other joint disorders	0.796	0.204
M23.2 Derangement of meniscus due to old tear or injury	0.798	0.202
M23.3 Other meniscus derangements	0.801	0.199
M20 Acquired deformities of fingers and toes	0.807	0.193
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.811	0.189
M20.1 Hallux valgus (acquired)	0.816	0.184
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.817	0.183
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.818	0.182
M23.8 Other internal derangements of knee	0.824	0.176
M35 Other systemic involvement of connective tissue	0.827	0.173
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.834	0.166
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)	0.835	0.165
M23.5 Chronic instability of knee	0.836	0.164
M33 Dermatopolymyositis	0.836	0.164
M25 Other joint disorders, not elsewhere classified	0.838	0.162
M20.3 Other deformity of hallux (acquired)	0.841	0.159
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.842	0.157
M23.30 Other meniscus derangements (Multiple sites)	0.843	0.157
M23.0 Cystic meniscus	0.843	0.157
M34 Systemic sclerosis	0.844	0.156
M35.0 Sicca syndrome [Sjogren]	0.845	0.155
M23.4 Loose body in knee	0.845	0.155
M25.5 Pain in joint	0.846	0.154
M23.1 Discoid meniscus (congenital)	0.848	0.152
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.849	0.151
M20.6 Acquired deformity of toe(s), unspecified	0.850	0.150
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.850	0.150
M22 Disorders of patella	0.850	0.150
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.851	0.149
M23.9 Internal derangement of knee, unspecified	0.852	0.148
M30 Polyarteritis nodosa and related conditions	0.852	0.147
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.854	0.145
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.855	0.145
M21 Other acquired deformities of limbs	0.856	0.144
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.857	0.143
M23.37 Other meniscus derangements-Capsular lig	0.857	0.143
M25.55 Pain in joint (Pelvic region and thigh)	0.857	0.143
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.857	0.143
M23.6 Other spontaneous disruption of ligament(s) of knee	0.858	0.142
M32 Systemic lupus erythematosus	0.858	0.142
M20.2 Hallux rigidus	0.858	0.142
M20.0 Deformity of finger(s)	0.861	0.139
M24 Other specific joint derangements	0.861	0.139
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.865	0.135
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.865	0.135
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.866	0.134
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.867	0.133
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.867	0.133
M31 Other necrotising vasculopathies	0.868	0.132
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.869	0.131
M35.7 Hypermobility syndrome	0.872	0.128
M33.2 Polymyositis	0.873	0.127
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.873	0.127
M23.87 Other internal derangements of knee (Capsular ligament)	0.874	0.125
M23.80 Other internal derangements of knee (Multiple sites)	0.874	0.125
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.875	0.125
M35.1 Other overlap syndromes	0.875	0.125
M35.9 Systemic involvement of connective tissue, unspecified	0.875	0.124
M35.6 Relapsing panniculitis [Weber-Christian]	0.875	0.124
M35.5 Multifocal fibrosclerosis	0.875	0.124
M35.4 Diffuse (eosinophilic) fasciitis	0.876	0.124
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.876	0.123
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)	0.877	0.123
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.877	0.123
M33.1 Other dermatomyositis	0.877	0.123
M35.8 Other specified systemic involvement of connective tissue	0.878	0.122
M35.2 Behcet's disease	0.878	0.122
M23.50 Chronic instability of knee (Multiple sites)	0.878	0.122
M23.52 Chronic instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.878	0.122
M33.9 Dermatopolymyositis, unspecified	0.878	0.121
M25.57 Pain in joint (Ankle and foot)	0.879	0.121
M20.4 Other hammer toe(s) (acquired)	0.879	0.120
M25.53 Pain in joint (Forearm)	0.880	0.120
M23.59 Chronic instability of knee (Unspecified ligament or Unspecified meniscus)	0.880	0.120
M23.42 Loose body in knee-Pst lig/hrn men	0.880	0.119
M25.54 Pain in joint (Hand)	0.880	0.119
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)	0.881	0.119
M34.1 CR(E)ST syndrome	0.881	0.119
M34.9 Systemic sclerosis, unspecified	0.882	0.118
M23.57 Chronic instability of knee (Capsular ligament)	0.882	0.118
M23.55 Chronic instability of knee (Posterior horn of lateral meniscus)	0.882	0.118
M23.54 Chronic instability of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.882	0.118
M23.53 Chronic instability of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.882	0.118
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.882	0.117
M33.0 Juvenile dermatomyositis	0.882	0.117
M23.56 Chronic instability of knee (Other and unspecified lateral meniscus)	0.883	0.117
M25.0 Haemarthrosis	0.883	0.117
M35.3 Polymyalgia rheumatica	0.883	0.117
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.883	0.116
M25.2 Flail joint	0.884	0.116
M25.1 Fistula of joint	0.884	0.116
M20.5 Other deformities of toe(s) (acquired)	0.885	0.115
M40-M43 Deforming dorsopathies	0.885	0.115
M25.56 Pain in joint (Lower leg)	0.885	0.115
M23.40 Loose body in knee-Mult sites	0.885	0.115
M25.58 Pain in joint (Other)	0.885	0.115
M25.8 Other specified joint disorders	0.885	0.114
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)	0.887	0.113
M23.43 Loose body in knee-Med lig/oth men	0.887	0.113
M23.07 Cystic meniscus-Capsular lig	0.887	0.113
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)	0.887	0.113
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.887	0.113
M23.00 Cystic meniscus (Multiple sites)	0.887	0.113
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.888	0.112
M34.2 Systemic sclerosis induced by drugs and chemicals	0.888	0.112
M23.47 Loose body in knee-Capsular lig	0.889	0.111
M23.45 Loose body in knee-Pst hrn lat men	0.889	0.111
M34.0 Progressive systemic sclerosis	0.889	0.111
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.889	0.110
M23.44 Loose body in knee-Lat lig/ant men	0.889	0.110
M23.41 Loose body in knee-Ant lig/hrn men	0.890	0.110
M22.4 Chondromalacia patellae	0.890	0.110
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)	0.890	0.110
M22.3 Other derangements of patella	0.890	0.110
M30.8 Other conditions related to polyarteritis nodosa	0.890	0.109
M22.0 Recurrent dislocation of patella	0.891	0.109
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)	0.891	0.109
M23.17 Discoid meniscus (congenital)-Capsular lig	0.891	0.109
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)	0.891	0.109
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.891	0.109
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)	0.891	0.109
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.891	0.109
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.891	0.109
M23.10 Discoid meniscus (congenital) (Multiple sites)	0.891	0.109
M23.46 Loose body in knee-O/unsp lat men	0.891	0.109
M25.3 Other instability of joint	0.891	0.109
M21.2 Flexion deformity	0.891	0.109
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.891	0.108
M21.4 Flat foot [pes planus] (acquired)	0.891	0.108
M25.59 Pain in joint (Site unspecified)	0.892	0.108
M25.50 Pain in joint (Multiple sites)	0.892	0.108
M65-M68 Disorders of synovium and tendon	0.892	0.108
M34.8 Other forms of systemic sclerosis	0.892	0.108
M86-M90 Other osteopathies	0.892	0.108
M22.1 Recurrent subluxation of patella	0.892	0.107
M24.8 Other specific joint derangements, not elsewhere classified	0.893	0.107
M25.51 Pain in joint (Shoulder region)	0.893	0.107
M22.2 Patellofemoral disorders	0.893	0.107
M24.0 Loose body in joint	0.893	0.106
M23.97 Internal derangement of knee, unspecified (Capsular ligament)	0.894	0.106
M23.96 Internal derangement of knee, unspecified (Other and unspecified lateral meniscus)	0.894	0.106
M23.95 Internal derangement of knee, unspecified (Posterior horn of lateral meniscus)	0.894	0.106
M23.94 Internal derangement of knee, unspecified (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.894	0.106
M23.92 Internal derangement of knee, unspecified (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.894	0.106
M23.90 Internal derangement of knee, unspecified (Multiple sites)	0.894	0.106
M21.8 Other specified acquired deformities of limbs	0.894	0.106
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.894	0.106
M30.2 Juvenile polyarteritis	0.894	0.106
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.894	0.106
M22.8 Other disorders of patella	0.894	0.106
M22.9 Disorder of patella, unspecified	0.894	0.106
M23.91 Internal derangement of knee, unspecified (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.894	0.105
M23.99 Internal derangement of knee, unspecified (Unspecified ligament or Unspecified meniscus)	0.894	0.105
M23.49 Loose body in knee-Unspec lig/men	0.895	0.105
M60-M63 Disorders of muscles	0.895	0.105
M23.93 Internal derangement of knee, unspecified (Medial collateral ligament or Other and unspecified medial meniscus)	0.895	0.105
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.895	0.104
M36.3 Arthropathy in other blood disorders	0.895	0.104
M36.2 Haemophilic arthropathy	0.895	0.104
M36.1 Arthropathy in neoplastic disease	0.895	0.104
M36.0 Dermato(poly)myositis in neoplastic disease	0.895	0.104
M25.9 Joint disorder, unspecified	0.895	0.104
M45-M49 Spondylopathies	0.896	0.104
M21.1 Varus deformity, not elsewhere classified	0.896	0.104
M30.0 Polyarteritis nodosa	0.897	0.103
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.897	0.103
M25.4 Effusion of joint	0.897	0.102
M91-M94 Chondropathies	0.898	0.102
M24.1 Other articular cartilage disorders	0.898	0.102
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.898	0.102
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.898	0.102
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.898	0.102
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.898	0.102
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.898	0.102
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.898	0.102
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.898	0.102
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.898	0.102
M32.9 Systemic lupus erythematosus, unspecified	0.898	0.102
M21.3 Wrist or foot drop (acquired)	0.898	0.101
M21.9 Acquired deformity of limb, unspecified	0.898	0.101
M24.7 Protrusio acetabuli	0.899	0.101
M32.0 Drug-induced systemic lupus erythematosus	0.899	0.101
M25.52 Pain in joint (Upper arm)	0.899	0.101
M21.6 Other acquired deformities of ankle and foot	0.899	0.101
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.899	0.101
M32.8 Other forms of systemic lupus erythematosus	0.899	0.101
M25.7 Osteophyte	0.900	0.100
M00-M03 Infectious arthropathies	0.900	0.100
M21.7 Unequal limb length (acquired)	0.900	0.099
M41 Scoliosis	0.901	0.099
M24.9 Joint derangement, unspecified	0.901	0.099
M25.6 Stiffness of joint, not elsewhere classified	0.902	0.098
M32.1 Systemic lupus erythematosus with organ or system involvement	0.902	0.098
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.902	0.098
M31.4 Aortic arch syndrome [Takayasu]	0.902	0.098
M31.7 Microscopic polyangiitis	0.902	0.097
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.903	0.097
M05-M14 Inflammatory polyarthropathies	0.903	0.097
M24.6 Ankylosis of joint	0.905	0.095
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.905	0.095
M31.2 Lethal midline granuloma	0.905	0.094
M21.0 Valgus deformity, not elsewhere classified	0.906	0.094
M24.4 Recurrent dislocation and subluxation of joint	0.906	0.094
M24.2 Disorder of ligament	0.906	0.094
M31.8 Other specified necrotising vasculopathies	0.906	0.094
M65 Synovitis and tenosynovitis	0.906	0.093
M31.0 Hypersensitivity angiitis	0.906	0.093
M31.1 Thrombotic microangiopathy	0.907	0.093
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.907	0.093
M31.9 Necrotising vasculopathy, unspecified	0.907	0.093
M80-M85 Disorders of bone density and structure	0.907	0.093
M24.5 Contracture of joint	0.908	0.091
M50-M54 Other dorsopathies	0.909	0.091
M45 Ankylosing spondylitis	0.909	0.091
M89 Other disorders of bone	0.910	0.090
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.910	0.089
M43 Other deforming dorsopathies	0.912	0.088
M31.3 Wegener's granulomatosis	0.912	0.088
M65.9 Synovitis and tenosynovitis, unspecified	0.914	0.086
M46 Other inflammatory spondylopathies	0.914	0.086
M31.6 Other giant cell arteritis	0.914	0.085
M25.84 Other specified joint disorders (Hand)	0.914	0.085
M25.06 Haemarthrosis (Lower leg)	0.915	0.085
M25.86 Other specified joint disorders (Lower leg)	0.915	0.085
M25.87 Other specified joint disorders (Ankle and foot)	0.915	0.085
M10 Gout	0.916	0.084
M25.09 Haemarthrosis (Site unspecified)	0.916	0.084
M25.08 Haemarthrosis (Other)	0.916	0.084
M25.07 Haemarthrosis (Ankle and foot)	0.916	0.084
M25.05 Haemarthrosis (Pelvic region and thigh)	0.916	0.084
M25.04 Haemarthrosis (Hand)	0.916	0.084
M25.03 Haemarthrosis (Forearm)	0.916	0.084
M25.02 Haemarthrosis (Upper arm)	0.916	0.084
M25.01 Haemarthrosis (Shoulder region)	0.916	0.084
M25.00 Haemarthrosis (Multiple sites)	0.916	0.084
M21.23 Flexion deformity (Forearm)	0.916	0.084
M62 Other disorders of muscle	0.916	0.084
M25.19 Fistula of joint (Site unspecified)	0.916	0.083
M25.18 Fistula of joint (Other)	0.916	0.083
M25.17 Fistula of joint (Ankle and foot)	0.916	0.083
M25.16 Fistula of joint (Lower leg)	0.916	0.083
M25.15 Fistula of joint (Pelvic region and thigh)	0.916	0.083
M25.14 Fistula of joint (Hand)	0.916	0.083
M25.13 Fistula of joint (Forearm)	0.916	0.083
M25.12 Fistula of joint (Upper arm)	0.916	0.083
M25.11 Fistula of joint (Shoulder region)	0.916	0.083
M25.10 Fistula of joint (Multiple sites)	0.916	0.083
M25.29 Flail joint (Site unspecified)	0.916	0.083
M25.28 Flail joint (Other)	0.916	0.083
M25.27 Flail joint (Ankle and foot)	0.916	0.083
M25.26 Flail joint (Lower leg)	0.916	0.083
M25.25 Flail joint (Pelvic region and thigh)	0.916	0.083
M25.24 Flail joint (Hand)	0.916	0.083
M25.23 Flail joint (Forearm)	0.916	0.083
M25.22 Flail joint (Upper arm)	0.916	0.083
M25.21 Flail joint (Shoulder region)	0.916	0.083
M25.20 Flail joint (Multiple sites)	0.916	0.083
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.917	0.083
M24.02 Loose body in joint (Upper arm)	0.917	0.083
M40 Kyphosis and lordosis	0.917	0.083
M45.X9 Ankylosing spondylitis (Site unspecified)	0.917	0.083
M42 Spinal osteochondrosis	0.917	0.083
M41.9 Scoliosis, unspecified	0.917	0.082
M24.16 Other articular cartilage disorders (Lower leg)	0.917	0.082
M25.89 Other specified joint disorders (Site unspecified)	0.918	0.082
M25.80 Other specified joint disorders (Multiple sites)	0.918	0.082
M87 Osteonecrosis	0.918	0.082
M25.82 Other specified joint disorders (Upper arm)	0.918	0.081
M70-M79 Other soft tissue disorders	0.918	0.082
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.918	0.081
M21.24 Flexion deformity (Hand)	0.919	0.081
M21.25 Flexion deformity (Pelvic region and thigh)	0.919	0.080
M25.88 Other specified joint disorders (Other)	0.919	0.080
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.920	0.080
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.920	0.080
M25.83 Other specified joint disorders (Forearm)	0.920	0.080
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.920	0.080
M92 Other juvenile osteochondrosis	0.920	0.080
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.920	0.079
M25.37 Other instability of joint (Ankle and foot)	0.921	0.079
M25.34 Other instability of joint (Hand)	0.921	0.079
M24.04 Loose body in joint (Hand)	0.921	0.079
M25.81 Other specified joint disorders (Shoulder region)	0.921	0.079
M41.8 Other forms of scoliosis	0.921	0.079
M86 Osteomyelitis	0.921	0.079
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.921	0.079
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.921	0.078
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.921	0.078
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.921	0.078
M25.39 Other instability of joint (Site unspecified)	0.921	0.078
M25.38 Other instability of joint (Other)	0.921	0.078
M25.35 Other instability of joint (Pelvic region and thigh)	0.921	0.078
M25.32 Other instability of joint (Upper arm)	0.921	0.078
M25.30 Other instability of joint (Multiple sites)	0.921	0.078
M21.29 Flexion deformity (Site unspecified)	0.922	0.078
M21.28 Flexion deformity (Other)	0.922	0.078
M21.21 Flexion deformity (Shoulder region)	0.922	0.078
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.922	0.078
M21.48 Flat foot [pes planus] (acquired)-Other	0.922	0.078
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.922	0.078
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.922	0.078
M21.44 Flat foot [pes planus] (acquired)-Hand	0.922	0.078
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.922	0.078
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.922	0.078
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.922	0.078
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.922	0.078
M21.20 Flexion deformity (Multiple sites)	0.922	0.078
M21.22 Flexion deformity (Upper arm)	0.922	0.078
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.922	0.078
M21.27 Flexion deformity (Ankle and foot)	0.922	0.078
M22.10 Recurrent subluxation of patella, unspecified knee	0.923	0.077
M25.78 Osteophyte (Other)	0.923	0.077
M24.01 Loose body in joint (Shoulder region)	0.923	0.077
M25.33 Other instability of joint (Forearm)	0.923	0.077
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.923	0.077
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.923	0.077
M25.45 Effusion of joint (Pelvic region and thigh)	0.923	0.076
M24.09 Loose body in joint (Site unspecified)	0.923	0.076
M24.08 Loose body in joint (Other)	0.923	0.076
M24.00 Loose body in joint (Multiple sites)	0.923	0.076
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.923	0.076
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.923	0.076
M21.88 Other specified acquired deformities of limbs-Other	0.923	0.076
M21.84 Other specified acquired deformities of limbs (Hand)	0.923	0.076
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.923	0.076
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.923	0.076
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.923	0.076
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.924	0.076
M25.36 Other instability of joint (Lower leg)	0.924	0.076
M24.07 Loose body in joint (Ankle and foot)	0.924	0.076
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.924	0.076
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.924	0.076
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.924	0.076
M25.77 Osteophyte (Ankle and foot)	0.924	0.076
M24.05 Loose body in joint (Pelvic region and thigh)	0.924	0.076
M24.06 Loose body in joint-Lower leg	0.924	0.076
M88 Paget's disease of bone [osteitis deformans]	0.924	0.076
M21.83 Other specified acquired deformities of limbs (Forearm)	0.924	0.076
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.924	0.075
M89.9 Disorder of bone, unspecified	0.924	0.076
M60 Myositis	0.924	0.075
M24.03 Loose body in joint (Forearm)	0.924	0.075
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.924	0.075
M63 Disorders of muscle in diseases classified elsewhere	0.924	0.075
M61 Calcification and ossification of muscle	0.924	0.075
M24.17 Other articular cartilage disorders (Ankle and foot)	0.925	0.075
M94 Other disorders of cartilage	0.925	0.075
M00 Pyogenic arthritis	0.925	0.075
M67 Other disorders of synovium and tendon	0.925	0.075
M25.42 Effusion of joint (Upper arm)	0.925	0.075
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.925	0.075
M21.18 Varus deformity, not elsewhere classified (Other)	0.925	0.075
M21.14 Varus deformity, not elsewhere classified (Hand)	0.925	0.075
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.925	0.075
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.925	0.075
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.925	0.075
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.925	0.075
M25.90 Joint disorder, unspecified (Multiple sites)	0.925	0.075
M25.98 Joint disorder, unspecified (Other)	0.925	0.075
M25.92 Joint disorder, unspecified (Upper arm)	0.925	0.074
M10.9 Gout, unspecified	0.925	0.075
M21.26 Flexion deformity (Lower leg)	0.925	0.074
M25.93 Joint disorder, unspecified (Forearm)	0.925	0.074
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.926	0.074
M25.31 Other instability of joint (Shoulder region)	0.926	0.074
M25.99 Joint disorder, unspecified (Site unspecified)	0.926	0.074
M24.75 Protrusio acetabuli-Pelvic/thigh	0.926	0.074
M54 Dorsalgia	0.926	0.074
M49 Spondylopathies in diseases classified elsewhere	0.926	0.074
M25.49 Effusion of joint (Site unspecified)	0.926	0.074
M25.48 Effusion of joint (Other)	0.926	0.074
M24.19 Other articular cartilage disorders (Site unspecified)	0.926	0.073
M24.18 Other articular cartilage disorders (Other)	0.926	0.073
M24.12 Other articular cartilage disorders (Upper arm)	0.926	0.073
M24.10 Other articular cartilage disorders (Multiple sites)	0.926	0.073
M25.94 Joint disorder, unspecified (Hand)	0.926	0.073
M25.91 Joint disorder, unspecified (Shoulder region)	0.927	0.073
M05 Seropositive rheumatoid arthritis	0.927	0.073
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.927	0.073
M84 Disorders of continuity of bone	0.927	0.073
M24.14 Other articular cartilage disorders (Hand)	0.927	0.073
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.927	0.073
M21.39 Wrist or foot drop (acquired)-Site unspec	0.927	0.073
M21.38 Wrist or foot drop (acquired)-Other	0.927	0.073
M21.36 Wrist or foot drop (acquired)-Lower leg	0.927	0.073
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.927	0.073
M21.34 Wrist or foot drop (acquired) (Hand)	0.927	0.073
M21.32 Wrist or foot drop (acquired)-Upper arm	0.927	0.073
M21.31 Wrist or foot drop (acquired)-Shldr region	0.927	0.073
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.927	0.073
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.927	0.073
M21.98 Acquired deformity of limb, unspecified-Other	0.927	0.073
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.927	0.073
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.927	0.073
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.927	0.073
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.927	0.073
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.927	0.073
M12 Other specific arthropathies	0.927	0.073
M24.79 Protrusio acetabuli-Site unspec	0.927	0.073
M24.78 Protrusio acetabuli-Other	0.927	0.073
M24.77 Protrusio acetabuli-Ankle/foot	0.927	0.073
M24.76 Protrusio acetabuli-Lower leg	0.927	0.073
M24.74 Protrusio acetabuli-Hand	0.927	0.073
M24.73 Protrusio acetabuli-Forearm	0.927	0.073
M24.72 Protrusio acetabuli-Upper arm	0.927	0.073
M24.71 Protrusio acetabuli-Shldr region	0.927	0.073
M24.70 Protrusio acetabuli-Mult sites	0.927	0.073
M25.97 Joint disorder, unspecified (Ankle and foot)	0.927	0.073
M25.41 Effusion of joint (Shoulder region)	0.927	0.073
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.927	0.072
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.927	0.072
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.927	0.072
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.927	0.072
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.927	0.072
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.927	0.072
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.927	0.072
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.927	0.072
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.927	0.072
M21.68 Other acquired deformities of ankle and foot-Other	0.927	0.072
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.927	0.072
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.927	0.072
M21.64 Other acquired deformities of ankle and foot-Hand	0.927	0.072
M21.63 Other acquired deformities of ankle and foot-Forearm	0.927	0.072
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.927	0.072
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.927	0.072
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.927	0.072
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.927	0.072
M21.33 Wrist or foot drop (acquired) (Forearm)	0.927	0.072
M93 Other osteochondropathies	0.927	0.072
M41.5 Other secondary scoliosis	0.927	0.072
M66 Spontaneous rupture of synovium and tendon	0.927	0.072
M21.94 Acquired deformity of limb, unspecified (Hand)	0.928	0.072
M24.13 Other articular cartilage disorders (Forearm)	0.928	0.072
M91 Juvenile osteochondrosis of hip and pelvis	0.928	0.072
M25.44 Effusion of joint (Hand)	0.928	0.072
M25.96 Joint disorder, unspecified (Lower leg)	0.928	0.072
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.928	0.072
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.928	0.072
M02 Reactive arthropathies	0.928	0.072
M25.43 Effusion of joint (Forearm)	0.928	0.072
M25.70 Osteophyte (Multiple sites)	0.928	0.072
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.928	0.072
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.928	0.072
M25.40 Effusion of joint (Multiple sites)	0.928	0.072
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.928	0.072
M21.79 Unequal limb length (acquired) (Site unspecified)	0.928	0.071
M21.78 Unequal limb length (acquired)-Other	0.928	0.071
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.928	0.071
M21.74 Unequal limb length (acquired) (Hand)	0.928	0.071
M21.72 Unequal limb length (acquired) (Upper arm)	0.928	0.071
M21.71 Unequal limb length (acquired)-Shldr region	0.928	0.071
M21.70 Unequal limb length (acquired) (Multiple sites)	0.928	0.071
M25.71 Osteophyte (Shoulder region)	0.929	0.071
M41.3 Thoracogenic scoliosis	0.929	0.071
M41.1 Juvenile idiopathic scoliosis	0.929	0.071
M41.0 Infantile idiopathic scoliosis	0.929	0.071
M65.1 Other infective (teno)synovitis	0.929	0.071
M43.1 Spondylolisthesis	0.929	0.071
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.929	0.071
M46.9 Inflammatory spondylopathy, unspecified	0.929	0.071
M24.27 Disorder of ligament (Ankle and foot)	0.929	0.071
M24.99 Joint derangement, unspecified (Site unspecified)	0.929	0.071
M24.98 Joint derangement, unspecified (Other)	0.929	0.071
M24.97 Joint derangement, unspecified (Ankle and foot)	0.929	0.071
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.929	0.071
M24.93 Joint derangement, unspecified (Forearm)	0.929	0.071
M24.92 Joint derangement, unspecified (Upper arm)	0.929	0.071
M24.90 Joint derangement, unspecified (Multiple sites)	0.929	0.071
M99 Biomechanical lesions, not elsewhere classified	0.929	0.071
M41.2 Other idiopathic scoliosis	0.929	0.071
M24.11 Other articular cartilage disorders (Shoulder region)	0.929	0.071
M21.73 Unequal limb length (acquired) (Forearm)	0.929	0.071
M41.4 Neuromuscular scoliosis	0.929	0.071
M25.79 Osteophyte (Site unspecified)	0.929	0.071
M25.73 Osteophyte (Forearm)	0.929	0.071
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.929	0.071
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.929	0.071
M53 Other dorsopathies, not elsewhere classified	0.929	0.071
M24.91 Joint derangement, unspecified (Shoulder region)	0.929	0.070
M24.94 Joint derangement, unspecified (Hand)	0.929	0.070
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.929	0.070
M24.96 Joint derangement, unspecified (Lower leg)	0.929	0.070
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.929	0.070
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.929	0.070
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.929	0.070
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.929	0.070
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.929	0.070
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.929	0.070
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.929	0.070
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.929	0.070
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.929	0.070
M21.76 Unequal limb length (acquired) (Lower leg)	0.929	0.070
M25.74 Osteophyte (Hand)	0.929	0.070
M25.72 Osteophyte (Upper arm)	0.930	0.070
M41.96 Scoliosis, unspecified (Lumbar region)	0.930	0.070
M90 Osteopathies in diseases classified elsewhere	0.930	0.070
M13 Other arthritis	0.930	0.070
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.930	0.070
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.930	0.070

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations