TreeWAS – Variant ID: rs11125529

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
J32.0 Chronic maxillary sinusitis	0.000	0.731	0.269
J32 Chronic sinusitis	0.000	0.773	0.227
J32.4 Chronic pansinusitis	0.000	0.789	0.211
J32.8 Other chronic sinusitis	0.000	0.792	0.208
J32.2 Chronic ethmoidal sinusitis	0.000	0.812	0.188
J32.1 Chronic frontal sinusitis	0.000	0.828	0.172
J32.3 Chronic sphenoidal sinusitis	0.000	0.837	0.163
M48.06 Spinal stenosis (Lumbar region)	0.041	0.959	0.000
M48.0 Spinal stenosis	0.037	0.963	0.000
M48.07 Spinal stenosis (Lumbosacral region)	0.034	0.966	0.000
M48.02 Spinal stenosis (Cervical region)	0.029	0.971	0.000
M48.00 Spinal stenosis (Multiple sites in spine)	0.028	0.972	0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)	0.028	0.972	0.000
M48.04 Spinal stenosis (Thoracic region)	0.028	0.972	0.000
M48.05 Spinal stenosis (Thoracolumbar region)	0.026	0.973	0.000
M48.03 Spinal stenosis (Cervicothoracic region)	0.026	0.973	0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)	0.026	0.973	0.000
M48.09 Spinal stenosis (Site unspecified)	0.022	0.978	0.000
M48 Other spondylopathies	0.021	0.979	0.000
J32.9 Chronic sinusitis, unspecified	0.000	0.981	0.019
M48.5 Collapsed vertebra, not elsewhere classified	0.016	0.984	0.000
M48.9 Spondylopathy, unspecified	0.016	0.984	0.000
M48.8 Other specified spondylopathies	0.015	0.985	0.000
M48.4 Fatigue fracture of vertebra	0.015	0.985	0.000
M48.3 Traumatic spondylopathy	0.015	0.985	0.000
M48.2 Kissing spine	0.015	0.985	0.000
M48.1 Ankylosing hyperostosis [Forestier]	0.015	0.985	0.000
Q21 Congenital malformations of cardiac septa	0.014	0.986	0.000
Q21.0 Ventricular septal defect	0.014	0.986	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.014	0.986	0.000
Q24 Other congenital malformations of heart	0.013	0.987	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.013	0.987	0.000
Q25 Congenital malformations of great arteries	0.013	0.987	0.000
M48.99 Spondylopathy, unspecified (Site unspecified)	0.013	0.987	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.012	0.988	0.000
Q24.8 Other specified congenital malformations of heart	0.012	0.988	0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.012	0.988	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.012	0.988	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.012	0.988	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.012	0.988	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.012	0.988	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.012	0.988	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.012	0.988	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.012	0.988	0.000
Q28 Other congenital malformations of circulatory system	0.012	0.988	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.012	0.988	0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.012	0.988	0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)	0.012	0.988	0.000
M48.96 Spondylopathy, unspecified (Lumbar region)	0.012	0.988	0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)	0.012	0.988	0.000
M48.94 Spondylopathy, unspecified (Thoracic region)	0.012	0.988	0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)	0.012	0.988	0.000
M48.92 Spondylopathy, unspecified (Cervical region)	0.012	0.988	0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)	0.012	0.988	0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)	0.012	0.988	0.000
Q25.1 Coarctation of aorta	0.011	0.989	0.000
Q21.1 Atrial septal defect	0.011	0.989	0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)	0.011	0.989	0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)	0.011	0.989	0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)	0.011	0.989	0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)	0.011	0.989	0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)	0.011	0.989	0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)	0.011	0.989	0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)	0.011	0.989	0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)	0.011	0.989	0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)	0.011	0.989	0.000
M48.29 Kissing spine (Site unspecified)	0.011	0.989	0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M48.27 Kissing spine (Lumbosacral region)	0.011	0.989	0.000
M48.26 Kissing spine (Lumbar region)	0.011	0.989	0.000
M48.25 Kissing spine (Thoracolumbar region)	0.011	0.989	0.000
M48.24 Kissing spine (Thoracic region)	0.011	0.989	0.000
M48.23 Kissing spine (Cervicothoracic region)	0.011	0.989	0.000
M48.22 Kissing spine (Cervical region)	0.011	0.989	0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)	0.011	0.989	0.000
M48.20 Kissing spine (Multiple sites in spine)	0.011	0.989	0.000
M48.39 Traumatic spondylopathy (Site unspecified)	0.011	0.989	0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)	0.011	0.989	0.000
M48.36 Traumatic spondylopathy (Lumbar region)	0.011	0.989	0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)	0.011	0.989	0.000
M48.34 Traumatic spondylopathy (Thoracic region)	0.011	0.989	0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)	0.011	0.989	0.000
M48.32 Traumatic spondylopathy (Cervical region)	0.011	0.989	0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)	0.011	0.989	0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)	0.011	0.989	0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)	0.011	0.989	0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)	0.011	0.989	0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)	0.011	0.989	0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)	0.011	0.989	0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)	0.011	0.989	0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)	0.011	0.989	0.000
M48.42 Fatigue fracture of vertebra (Cervical region)	0.011	0.989	0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)	0.011	0.989	0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)	0.011	0.989	0.000
M48.89 Other specified spondylopathies (Site unspecified)	0.011	0.989	0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)	0.011	0.989	0.000
M48.87 Other specified spondylopathies (Lumbosacral region)	0.011	0.989	0.000
M48.86 Other specified spondylopathies (Lumbar region)	0.011	0.989	0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)	0.011	0.989	0.000
M48.84 Other specified spondylopathies (Thoracic region)	0.011	0.989	0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)	0.011	0.989	0.000
M48.82 Other specified spondylopathies (Cervical region)	0.011	0.989	0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)	0.011	0.989	0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)	0.011	0.989	0.000
Q25.3 Stenosis of aorta	0.011	0.989	0.000
Q21.8 Other congenital malformations of cardiac septa	0.010	0.989	0.000
Q21.4 Aortopulmonary septal defect	0.010	0.989	0.000
Q21.3 Tetralogy of Fallot	0.010	0.989	0.000
Q21.2 Atrioventricular septal defect	0.010	0.989	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.010	0.989	0.000
D86.9 Sarcoidosis, unspecified	0.011	0.989	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.010	0.990	0.000
D86 Sarcoidosis	0.010	0.990	0.000
Q26 Congenital malformations of great veins	0.010	0.990	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.010	0.990	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.010	0.990	0.000
Q25.0 Patent ductus arteriosus	0.010	0.990	0.000
Q27 Other congenital malformations of peripheral vascular system	0.010	0.990	0.000
Q24.6 Congenital heart block	0.010	0.990	0.000
Q24.5 Malformation of coronary vessels	0.010	0.990	0.000
Q24.4 Congenital subaortic stenosis	0.010	0.990	0.000
Q24.3 Pulmonary infundibular stenosis	0.010	0.990	0.000
Q24.2 Cor triatriatum	0.010	0.990	0.000
Q24.1 Levocardia	0.010	0.990	0.000
Q24.0 Dextrocardia	0.010	0.990	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.009	0.990	0.000
Q25.8 Other congenital malformations of great arteries	0.009	0.990	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.009	0.990	0.000
Q25.6 Stenosis of pulmonary artery	0.009	0.990	0.000
Q25.5 Atresia of pulmonary artery	0.009	0.990	0.000
Q25.4 Other congenital malformations of aorta	0.009	0.990	0.000
Q25.2 Atresia of aorta	0.009	0.990	0.000
D86.1 Sarcoidosis of lymph nodes	0.010	0.990	0.000
Q28.2 Arteriovenous malformation of cerebral vessels	0.009	0.991	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.009	0.991	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.009	0.991	0.000
Q28.3 Other malformations of cerebral vessels	0.009	0.991	0.000
Q28.1 Other malformations of precerebral vessels	0.009	0.991	0.000
Q23 Congenital malformations of aortic and mitral valves	0.009	0.991	0.000
D86.0 Sarcoidosis of lung	0.009	0.991	0.000
R25.1 Tremor, unspecified	0.000	0.991	0.009
D86.3 Sarcoidosis of skin	0.008	0.992	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.008	0.992	0.000
H54.7 Unspecified visual loss	0.008	0.992	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.008	0.992	0.000
M95.0 Acquired deformity of nose	0.000	0.992	0.008
D86.8 Sarcoidosis of other and combined sites	0.008	0.992	0.000
Q61 Cystic kidney disease	0.008	0.992	0.000
C78.2 Secondary malignant neoplasm of pleura	0.008	0.992	0.000
H54.0 Blindness, both eyes	0.008	0.992	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.007	0.992	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.007	0.992	0.000
Q20.6 Isomerism of atrial appendages	0.007	0.992	0.000
Q20.5 Discordant atrioventricular connexion	0.007	0.992	0.000
Q20.4 Double inlet ventricle	0.007	0.992	0.000
Q20.3 Discordant ventriculoarterial connexion	0.007	0.992	0.000
Q20.2 Double outlet left ventricle	0.007	0.992	0.000
Q20.1 Double outlet right ventricle	0.007	0.992	0.000
Q20.0 Common arterial trunk	0.007	0.992	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.007	0.992	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.007	0.992	0.000
Q22.6 Hypoplastic right heart syndrome	0.007	0.992	0.000
Q22.5 Ebstein's anomaly	0.007	0.992	0.000
Q22.4 Congenital tricuspid stenosis	0.007	0.992	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.007	0.992	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.007	0.992	0.000
Q22.1 Congenital pulmonary valve stenosis	0.007	0.992	0.000
Q22.0 Pulmonary valve atresia	0.007	0.992	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.007	0.992	0.000
Q26.8 Other congenital malformations of great veins	0.007	0.992	0.000
Q26.6 Portal vein-hepatic artery fistula	0.007	0.992	0.000
Q26.5 Anomalous portal venous connexion	0.007	0.992	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.007	0.992	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.007	0.992	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.007	0.992	0.000
Q26.1 Persistent left superior vena cava	0.007	0.992	0.000
Q26.0 Congenital stenosis of vena cava	0.007	0.992	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.007	0.992	0.000
H54 Blindness and low vision	0.008	0.992	0.000
Q61.3 Polycystic kidney, unspecified	0.007	0.993	0.000
H54.4 Blindness, one eye	0.007	0.993	0.000
Q27.4 Congenital phlebectasia	0.007	0.993	0.000
Q27.2 Other congenital malformations of renal artery	0.007	0.993	0.000
Q27.1 Congenital renal artery stenosis	0.007	0.993	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.007	0.993	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.007	0.993	0.000
Q61.2 Polycystic kidney, adult type	0.007	0.993	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.007	0.993	0.000
Q60-Q64 Congenital malformations of the urinary system	0.007	0.993	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.007	0.993	0.000
Z47.8 Other specified orthopaedic follow-up care	0.007	0.993	0.000
K85.9 Acute pancreatitis, unspecified	0.000	0.993	0.007
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.006	0.993	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.006	0.993	0.000
Q23.4 Hypoplastic left heart syndrome	0.006	0.993	0.000
Q23.3 Congenital mitral insufficiency	0.006	0.993	0.000
Q23.2 Congenital mitral stenosis	0.006	0.993	0.000
Q61.9 Cystic kidney disease, unspecified	0.006	0.993	0.000
Q80-Q89 Other congenital malformations	0.006	0.994	0.000
Q27.3 Peripheral arteriovenous malformation	0.006	0.994	0.000
Q61.5 Medullary cystic kidney	0.006	0.994	0.000
Q23.0 Congenital stenosis of aortic valve	0.006	0.994	0.000
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.994	0.006
Q82 Other congenital malformations of skin	0.006	0.994	0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.006	0.994	0.000
H54.1 Blindness, one eye, low vision, other eye	0.006	0.994	0.000
Q64 Other congenital malformations of urinary system	0.006	0.994	0.000
Q82.5 Congenital nonneoplastic naevus	0.006	0.994	0.000
H54.5 Low vision, one eye	0.006	0.994	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.006	0.994	0.000
Q61.8 Other cystic kidney diseases	0.006	0.994	0.000
Q61.4 Renal dysplasia	0.006	0.994	0.000
Q61.1 Polycystic kidney, infantile type	0.006	0.994	0.000
H54.6 Unqualified visual loss, one eye	0.006	0.994	0.000
H54.3 Unqualified visual loss, both eyes	0.006	0.994	0.000
H54.2 Low vision, both eyes	0.006	0.994	0.000
Q61.0 Congenital single renal cyst	0.006	0.994	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.005	0.994	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.994	0.000
C78.7 Secondary malignant neoplasm of liver	0.006	0.994	0.000
D80 Immunodeficiency with predominantly antibody defects	0.005	0.995	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.005	0.995	0.000
C78.1 Secondary malignant neoplasm of mediastinum	0.005	0.995	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.005	0.995	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.005	0.995	0.000
Q35-Q37 Cleft lip and cleft palate	0.005	0.995	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.005	0.995	0.000
Q89 Other congenital malformations, not elsewhere classified	0.005	0.995	0.000
Q82.0 Hereditary lymphoedema	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.005	0.995	0.000
Q82.2 Mastocytosis	0.005	0.995	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.005	0.995	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.005	0.995	0.000
Q84 Other congenital malformations of integument	0.005	0.995	0.000
Q83 Congenital malformations of breast	0.005	0.995	0.000
Q81 Epidermolysis bullosa	0.005	0.995	0.000
Q80 Congenital ichthyosis	0.005	0.995	0.000
D83 Common variable immunodeficiency	0.005	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
D82 Immunodeficiency associated with other major defects	0.005	0.995	0.000
D81 Combined immunodeficiencies	0.005	0.995	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.995	0.005
Q99 Other chromosome abnormalities, not elsewhere classified	0.004	0.995	0.000
Q82.9 Congenital malformation of skin, unspecified	0.004	0.995	0.000
Q82.4 Ectodermal dysplasia (anhidrotic)	0.004	0.995	0.000
Q82.3 Incontinentia pigmenti	0.004	0.995	0.000
Q82.1 Xeroderma pigmentosum	0.004	0.995	0.000
C78.4 Secondary malignant neoplasm of small intestine	0.004	0.995	0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.004	0.995	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.004	0.995	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.004	0.995	0.000
Q64.8 Other specified congenital malformations of urinary system	0.004	0.995	0.000
Q64.7 Other congenital malformations of bladder and urethra	0.004	0.995	0.000
Q64.6 Congenital diverticulum of bladder	0.004	0.995	0.000
Q64.5 Congenital absence of bladder and urethra	0.004	0.995	0.000
Q64.4 Malformation of urachus	0.004	0.995	0.000
Q64.2 Congenital posterior urethral valves	0.004	0.995	0.000
Q64.1 Exstrophy of urinary bladder	0.004	0.995	0.000
Q64.0 Epispadias	0.004	0.995	0.000
D84 Other immunodeficiencies	0.004	0.996	0.000
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.004	0.996	0.000
C73 Malignant neoplasm of thyroid gland	0.004	0.996	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.004	0.996	0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.004	0.996	0.000
Z47 Other orthopaedic follow-up care	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.004	0.996	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.004	0.996	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.004	0.996	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.004	0.996	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.004	0.996	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.004	0.996	0.000
Q90 Down's syndrome	0.004	0.996	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.004	0.996	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.004	0.996	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.004	0.996	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.004	0.996	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.004	0.996	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.004	0.996	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.004	0.996	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.004	0.996	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.004	0.996	0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.004	0.996	0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.000	0.996	0.004
Q89.2 Congenital malformations of other endocrine glands	0.004	0.996	0.000
Q96 Turner's syndrome	0.004	0.996	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.004	0.996	0.000
Q87.4 Marfan's syndrome	0.004	0.996	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.004	0.996	0.000
Q99.8 Other specified chromosome abnormalities	0.004	0.996	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.004	0.996	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.004	0.996	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.004	0.996	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.004	0.996	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.004	0.996	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.996	0.000
Q33 Congenital malformations of lung	0.004	0.996	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.996	0.000
Q31 Congenital malformations of larynx	0.004	0.996	0.000
Q30 Congenital malformations of nose	0.004	0.996	0.000
Q37 Cleft palate with cleft lip	0.004	0.996	0.000
Q36 Cleft lip	0.004	0.996	0.000
Q35 Cleft palate	0.004	0.996	0.000
Q89.9 Congenital malformation, unspecified	0.004	0.996	0.000
Q89.8 Other specified congenital malformations	0.004	0.996	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.996	0.000
Q89.4 Conjoined twins	0.004	0.996	0.000
Q89.3 Situs inversus	0.004	0.996	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.996	0.000
Q89.0 Congenital malformations of spleen	0.004	0.996	0.000
Q62.8 Other congenital malformations of ureter	0.004	0.996	0.000
Q62.7 Congenital vesico-uretero-renal reflux	0.004	0.996	0.000
Q62.6 Malposition of ureter	0.004	0.996	0.000
Q62.4 Agenesis of ureter	0.004	0.996	0.000
Q62.3 Other obstructive defects of renal pelvis and ureter	0.004	0.996	0.000
Q62.2 Congenital megaloureter	0.004	0.996	0.000
Q62.1 Atresia and stenosis of ureter	0.004	0.996	0.000
Q62.0 Congenital hydronephrosis	0.004	0.996	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.004	0.996	0.000
D89.3 Immune reconstitution syndrome	0.004	0.996	0.000
D89.1 Cryoglobulinaemia	0.004	0.996	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.004	0.996	0.000
Q50-Q56 Congenital malformations of genital organs	0.004	0.996	0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.004	0.996	0.000
D83.9 Common variable immunodeficiency, unspecified	0.004	0.996	0.000
R25 Abnormal involuntary movements	0.000	0.996	0.004
Q60.6 Potter's syndrome	0.004	0.996	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.996	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.996	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.996	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.996	0.000
Q60.2 Renal agenesis, unspecified	0.004	0.996	0.000
Q80.9 Congenital ichthyosis, unspecified	0.004	0.996	0.000
Q80.8 Other congenital ichthyosis	0.004	0.996	0.000
Q80.4 Harlequin foetus	0.004	0.996	0.000
Q80.3 Congenital bullous ichthyosiform erythroderma	0.004	0.996	0.000
Q80.2 Lamellar ichthyosis	0.004	0.996	0.000
Q80.1 X-linked ichthyosis	0.004	0.996	0.000
Q80.0 Ichthyosis vulgaris	0.004	0.996	0.000
Q81.9 Epidermolysis bullosa, unspecified	0.004	0.996	0.000
Q81.8 Other epidermolysis bullosa	0.004	0.996	0.000
Q81.2 Epidermolysis bullosa dystrophica	0.004	0.996	0.000
Q81.1 Epidermolysis bullosa letalis	0.004	0.996	0.000
Q81.0 Epidermolysis bullosa simplex	0.004	0.996	0.000
Q83.9 Congenital malformation of breast, unspecified	0.004	0.996	0.000
Q83.8 Other congenital malformations of breast	0.004	0.996	0.000
Q83.3 Accessory nipple	0.004	0.996	0.000
Q83.2 Absent nipple	0.004	0.996	0.000
Q83.1 Accessory breast	0.004	0.996	0.000
Q83.0 Congenital absence of breast with absent nipple	0.004	0.996	0.000
Q84.9 Congenital malformation of integument, unspecified	0.004	0.996	0.000
Q84.8 Other specified congenital malformations of integument	0.004	0.996	0.000
Q84.6 Other congenital malformations of nails	0.004	0.996	0.000
Q84.5 Enlarged and hypertrophic nails	0.004	0.996	0.000
Q84.4 Congenital leukonychia	0.004	0.996	0.000
Q84.3 Anonychia	0.004	0.996	0.000
Q84.2 Other congenital malformations of hair	0.004	0.996	0.000
Q84.1 Congenital morphological disturbances of hair, not elsewhere classified	0.004	0.996	0.000
Q84.0 Congenital alopecia	0.004	0.996	0.000
Q86.8 Other congenital malformation syndromes due to known exogenous causes	0.004	0.996	0.000
Q86.2 Dysmorphism due to warfarin	0.004	0.996	0.000
Q86.1 Foetal hydantoin syndrome	0.004	0.996	0.000
Q86.0 Foetal alcohol syndrome (dysmorphic)	0.004	0.996	0.000
G40 Epilepsy	0.004	0.996	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.004	0.996	0.000
D83.8 Other common variable immunodeficiencies	0.004	0.996	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.004	0.996	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.004	0.996	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.004	0.996	0.000
Q62.5 Duplication of ureter	0.003	0.996	0.000
Q85.9 Phakomatosis, unspecified	0.004	0.996	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
Q85.8 Other phakomatoses, not elsewhere classified	0.003	0.996	0.000
Q85.1 Tuberous sclerosis	0.003	0.996	0.000
D81.9 Combined immunodeficiency, unspecified	0.003	0.996	0.000
D81.8 Other combined immunodeficiencies	0.003	0.996	0.000
D81.7 Major histocompatibility complex class II deficiency	0.003	0.996	0.000
D81.6 Major histocompatibility complex class I deficiency	0.003	0.996	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.003	0.996	0.000
D81.4 Nezelof's syndrome	0.003	0.996	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.003	0.996	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.003	0.996	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.003	0.996	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.003	0.996	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.003	0.996	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.003	0.996	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.003	0.996	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.003	0.996	0.000
D82.2 Immunodeficiency with short-limbed stature	0.003	0.996	0.000
D82.1 Di George's syndrome	0.003	0.996	0.000
D82.0 Wiskott-Aldrich syndrome	0.003	0.996	0.000
G40.9 Epilepsy, unspecified	0.004	0.996	0.000
Q99.9 Chromosomal abnormality, unspecified	0.003	0.996	0.000
Q99.2 Fragile X chromosome	0.003	0.996	0.000
Q99.1 46,XX true hermaphrodite	0.003	0.996	0.000
Q99.0 Chimera 46,XX/46,XY	0.003	0.996	0.000
Q82.8 Other specified congenital malformations of skin	0.003	0.996	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.996	0.004
Q98.4 Klinefelter's syndrome, unspecified	0.003	0.996	0.000
Q65 Congenital deformities of hip	0.003	0.996	0.000
E55.9 Vitamin D deficiency, unspecified	0.004	0.996	0.000
C50.2 Upper-inner quadrant of breast	0.004	0.996	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.003	0.996	0.000
Q75 Other congenital malformations of skull and face bones	0.003	0.996	0.000
Q74 Other congenital malformations of limb(s)	0.003	0.996	0.000
Q73 Reduction defects of unspecified limb	0.003	0.996	0.000
Q72 Reduction defects of lower limb	0.003	0.996	0.000
Q71 Reduction defects of upper limb	0.003	0.996	0.000
Q70 Syndactyly	0.003	0.996	0.000
Q69 Polydactyly	0.003	0.996	0.000
Q68 Other congenital musculoskeletal deformities	0.003	0.996	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.003	0.996	0.000
Q60.0 Renal agenesis, unilateral	0.003	0.997	0.000
N99.2 Postprocedural adhesions of vagina	0.000	0.997	0.003
Q78 Other osteochondrodysplasias	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
D84.1 Defects in the complement system	0.003	0.997	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.003	0.997	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
Q98.9 Sex chromosome abnormality, male phenotype, unspecified	0.003	0.997	0.000
Q98.8 Other specified sex chromosome abnormalities, male phenotype	0.003	0.997	0.000
Q98.7 Male with sex chromosome mosaicism	0.003	0.997	0.000
Q98.6 Male with structurally abnormal sex chromosome	0.003	0.997	0.000
Q98.5 Karyotype 47,XYY	0.003	0.997	0.000
Q98.3 Other male with 46,XX karyotype	0.003	0.997	0.000
Q98.2 Klinefelter's syndrome, male with 46,XX karyotype	0.003	0.997	0.000
Q98.1 Klinefelter's syndrome, male with more than two X chromosomes	0.003	0.997	0.000
Q98.0 Klinefelter's syndrome karyotype 47,XXY	0.003	0.997	0.000
Q66 Congenital deformities of feet	0.003	0.997	0.000
M95.2 Other acquired deformity of head	0.000	0.997	0.003
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.003	0.997	0.000
Q39 Congenital malformations of oesophagus	0.003	0.997	0.000
Q45 Other congenital malformations of digestive system	0.003	0.997	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.003	0.997	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.003	0.997	0.000
Q40 Other congenital malformations of upper alimentary tract	0.003	0.997	0.000
Q63 Other congenital malformations of kidney	0.003	0.997	0.001
Q90.9 Down's syndrome, unspecified	0.003	0.997	0.000
Q90.2 Trisomy 21, translocation	0.003	0.997	0.000
Q90.1 Trisomy 21, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q90.0 Trisomy 21, meiotic nondisjunction	0.003	0.997	0.000
Q91.7 Patau's syndrome, unspecified	0.003	0.997	0.000
Q91.6 Trisomy 13, translocation	0.003	0.997	0.000
Q91.5 Trisomy 13, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q91.4 Trisomy 13, meiotic nondisjunction	0.003	0.997	0.000
Q91.3 Edwards' syndrome, unspecified	0.003	0.997	0.000
Q91.2 Trisomy 18, translocation	0.003	0.997	0.000
Q91.1 Trisomy 18, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q91.0 Trisomy 18, meiotic nondisjunction	0.003	0.997	0.000
Q92.9 Trisomy and partial trisomy of autosomes, unspecified	0.003	0.997	0.000
Q92.8 Other specified trisomies and partial trisomies of autosomes	0.003	0.997	0.000
Q92.7 Triploidy and polyploidy	0.003	0.997	0.000
Q92.6 Extra marker chromosomes	0.003	0.997	0.000
Q92.5 Duplications with other complex rearrangements	0.003	0.997	0.000
Q92.4 Duplications seen only at prometaphase	0.003	0.997	0.000
Q92.3 Minor partial trisomy	0.003	0.997	0.000
Q92.2 Major partial trisomy	0.003	0.997	0.000
Q92.1 Whole chromosome trisomy, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q92.0 Whole chromosome trisomy, meiotic nondisjunction	0.003	0.997	0.000
Q93.9 Deletion from autosomes, unspecified	0.003	0.997	0.000
Q93.8 Other deletions from the autosomes	0.003	0.997	0.000
Q93.7 Deletions with other complex rearrangements	0.003	0.997	0.000
Q93.6 Deletions seen only at prometaphase	0.003	0.997	0.000
Q93.5 Other deletions of part of a chromosome	0.003	0.997	0.000
Q93.4 Deletion of short arm of chromosome 5	0.003	0.997	0.000
Q93.3 Deletion of short arm of chromosome 4	0.003	0.997	0.000
Q93.2 Chromosome replaced with ring or dicentric	0.003	0.997	0.000
Q93.1 Whole chromosome monosomy, mosaicism (mitotic nondisjunction)	0.003	0.997	0.000
Q93.0 Whole chromosome monosomy, meiotic nondisjunction	0.003	0.997	0.000
Q95.9 Balanced rearrangement and structural marker, unspecified	0.003	0.997	0.000
Q95.8 Other balanced rearrangements and structural markers	0.003	0.997	0.000
Q95.5 Individuals with autosomal fragile site	0.003	0.997	0.000
Q95.4 Individuals with marker heterochromatin	0.003	0.997	0.000
Q95.3 Balanced sex/autosomal rearrangement in abnormal individual	0.003	0.997	0.000
Q95.2 Balanced autosomal rearrangement in abnormal individual	0.003	0.997	0.000
Q95.1 Chromosome inversion in normal individual	0.003	0.997	0.000
Q95.0 Balanced translocation and insertion in normal individual	0.003	0.997	0.000
Q97.9 Sex chromosome abnormality, female phenotype, unspecified	0.003	0.997	0.000
Q97.8 Other specified sex chromosome abnormalities, female phenotype	0.003	0.997	0.000
Q97.3 Female with 46,XY karyotype	0.003	0.997	0.000
Q97.2 Mosaicism, lines with various numbers of X chromosomes	0.003	0.997	0.000
Q97.1 Female with more than three X chromosomes	0.003	0.997	0.000
Q97.0 Karyotype 47,XXX	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.003	0.997	0.000
Q04 Other congenital malformations of brain	0.003	0.997	0.000
Q03 Congenital hydrocephalus	0.003	0.997	0.000
Q01 Encephalocele	0.003	0.997	0.000
Q00 Anencephaly and similar malformations	0.003	0.997	0.000
Q02 Microcephaly	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.003	0.997	0.000
H54.9 Unspecified visual impairment (binocular)	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations