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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11208446
log Bayes Factor = <0.0001
Chromosome 1   position 64,868,352  (GRCh37) Explore rs11208446 on Ensembl!
Variant rs11208446 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.9 Rheumatoid arthritis, unspecified
0.022 0.978 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.021 0.979 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.021 0.979 0.000
I49.3 Ventricular premature depolarisation
0.020 0.980 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.020 0.980 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.019 0.981 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.019 0.981 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.018 0.982 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.017 0.983 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.017 0.983 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.017 0.983 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.016 0.984 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.016 0.984 0.000
M41.9 Scoliosis, unspecified
0.016 0.984 0.000
I45.1 Other and unspecified right bundle-branch block
0.015 0.985 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.013 0.987 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.012 0.988 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.012 0.988 0.000
I34.0 Mitral (valve) insufficiency
0.012 0.988 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.012 0.988 0.000
I74 Arterial embolism and thrombosis
0.012 0.988 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.011 0.988 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.011 0.988 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.011 0.988 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.011 0.988 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.011 0.988 0.000
M06 Other rheumatoid arthritis
0.011 0.989 0.000
I34 Nonrheumatic mitral valve disorders
0.011 0.989 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.011 0.989 0.000
I34.1 Mitral (valve) prolapse
0.011 0.989 0.000
M20.4 Other hammer toe(s) (acquired)
0.011 0.989 0.000
I45 Other conduction disorders
0.010 0.990 0.000
I49 Other cardiac arrhythmias
0.010 0.990 0.000
M41 Scoliosis
0.010 0.990 0.000
I77 Other disorders of arteries and arterioles
0.010 0.990 0.000
I70 Atherosclerosis
0.010 0.990 0.000
I35.9 Aortic valve disorder, unspecified
0.010 0.990 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.010 0.990 0.000
I35 Nonrheumatic aortic valve disorders
0.010 0.990 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.010 0.990 0.000
I35.1 Aortic (valve) insufficiency
0.010 0.990 0.000
I30-I52 Other forms of heart disease
0.010 0.990 0.000
I77.1 Stricture of artery
0.010 0.990 0.000
I74.5 Embolism and thrombosis of iliac artery
0.010 0.990 0.000
D12.0 Caecum
0.010 0.990 0.000
I78 Diseases of capillaries
0.010 0.990 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.009 0.991 0.000
I70.0 Atherosclerosis of aorta
0.009 0.991 0.000
I77.0 Arteriovenous fistula, acquired
0.009 0.991 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.009 0.991 0.000
C56 Malignant neoplasm of ovary
0.009 0.991 0.000
I78.1 Naevus, nonneoplastic
0.009 0.991 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.009 0.991 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.008 0.991 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.008 0.991 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.008 0.991 0.000
I33 Acute and subacute endocarditis
0.008 0.991 0.000
M06.8 Other specified rheumatoid arthritis
0.008 0.992 0.000
M06.2 Rheumatoid bursitis
0.008 0.992 0.000
M06.1 Adult-onset Still's disease
0.008 0.992 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.008 0.992 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.008 0.992 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.008 0.992 0.000
I49.1 Atrial premature depolarisation
0.008 0.992 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.008 0.992 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.008 0.992 0.000
I45.4 Nonspecific intraventricular block
0.008 0.992 0.000
I72 Other aneurysm
0.008 0.992 0.000
I46 Cardiac arrest
0.008 0.992 0.000
I74.8 Embolism and thrombosis of other arteries
0.008 0.992 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.008 0.992 0.000
M05 Seropositive rheumatoid arthritis
0.008 0.992 0.000
I49.5 Sick sinus syndrome
0.008 0.992 0.000
I45.5 Other specified heart block
0.008 0.992 0.000
I45.3 Trifascicular block
0.008 0.992 0.000
M05-M14 Inflammatory polyarthropathies
0.008 0.992 0.000
I45.0 Right fascicular block
0.008 0.992 0.000
I77.8 Other specified disorders of arteries and arterioles
0.008 0.992 0.000
I33.0 Acute and subacute infective endocarditis
0.008 0.992 0.000
I49.2 Junctional premature depolarisation
0.008 0.992 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.008 0.992 0.000
M41.8 Other forms of scoliosis
0.007 0.992 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.007 0.992 0.000
M41.5 Other secondary scoliosis
0.007 0.992 0.000
M41.4 Neuromuscular scoliosis
0.007 0.992 0.000
M41.3 Thoracogenic scoliosis
0.007 0.992 0.000
M41.2 Other idiopathic scoliosis
0.007 0.992 0.000
M41.1 Juvenile idiopathic scoliosis
0.007 0.992 0.000
M41.0 Infantile idiopathic scoliosis
0.007 0.992 0.000
I77.5 Necrosis of artery
0.007 0.992 0.000
I77.4 Coeliac artery compression syndrome
0.007 0.992 0.000
I77.3 Arterial fibromuscular dysplasia
0.007 0.992 0.000
I77.2 Rupture of artery
0.007 0.992 0.000
M06.3 Rheumatoid nodule
0.007 0.992 0.000
I70.9 Generalised and unspecified atherosclerosis
0.007 0.992 0.000
I70.8 Atherosclerosis of other arteries
0.007 0.992 0.000
I70.1 Atherosclerosis of renal artery
0.007 0.992 0.000
M06.4 Inflammatory polyarthropathy
0.007 0.992 0.000
I45.8 Other specified conduction disorders
0.007 0.992 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.007 0.993 0.000
M06.0 Seronegative rheumatoid arthritis
0.007 0.993 0.000
I72.4 Aneurysm of artery of lower extremity
0.007 0.993 0.000
I35.8 Other aortic valve disorders
0.007 0.993 0.000
I52 Other heart disorders in diseases classified elsewhere
0.007 0.993 0.000
I48 Atrial fibrillation and flutter
0.007 0.993 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.007 0.993 0.000
I41 Myocarditis in diseases classified elsewhere
0.007 0.993 0.000
I40 Acute myocarditis
0.007 0.993 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.007 0.993 0.000
I37 Pulmonary valve disorders
0.007 0.993 0.000
I32 Pericarditis in diseases classified elsewhere
0.007 0.993 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.007 0.993 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.007 0.993 0.000
I71 Aortic aneurysm and dissection
0.007 0.993 0.000
C51-C58 Malignant neoplasms of female genital organs
0.007 0.993 0.000
I78.8 Other diseases of capillaries
0.007 0.993 0.000
I78.9 Disease of capillaries, unspecified
0.007 0.993 0.000
I45.6 Preexcitation syndrome
0.007 0.993 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.007 0.993 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.007 0.993 0.000
I49.4 Other and unspecified premature depolarisation
0.007 0.993 0.000
I70.01 Atherosclerosis of aorta (with gangrene)
0.007 0.993 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.007 0.993 0.000
O70.0 First degree perineal laceration during delivery
0.007 0.993 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.007 0.993 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.007 0.993 0.000
I46.9 Cardiac arrest, unspecified
0.007 0.993 0.000
C53 Malignant neoplasm of cervix uteri
0.006 0.993 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.006 0.993 0.000
I33.9 Acute endocarditis, unspecified
0.006 0.994 0.000
I42 Cardiomyopathy
0.006 0.994 0.000
M06.19 Adult-onset Still's disease (Site unspecified)
0.006 0.994 0.000
M06.18 Adult-onset Still's disease (Other)
0.006 0.994 0.000
M06.17 Adult-onset Still's disease (Ankle and foot)
0.006 0.994 0.000
M06.16 Adult-onset Still's disease (Lower leg)
0.006 0.994 0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.006 0.994 0.000
M06.14 Adult-onset Still's disease (Hand)
0.006 0.994 0.000
M06.13 Adult-onset Still's disease (Forearm)
0.006 0.994 0.000
M06.12 Adult-onset Still's disease (Upper arm)
0.006 0.994 0.000
M06.11 Adult-onset Still's disease (Shoulder region)
0.006 0.994 0.000
M06.10 Adult-onset Still's disease (Multiple sites)
0.006 0.994 0.000
M06.29 Rheumatoid bursitis (Site unspecified)
0.006 0.994 0.000
M06.28 Rheumatoid bursitis (Other)
0.006 0.994 0.000
M06.27 Rheumatoid bursitis (Ankle and foot)
0.006 0.994 0.000
M06.26 Rheumatoid bursitis (Lower leg)
0.006 0.994 0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.006 0.994 0.000
M06.24 Rheumatoid bursitis (Hand)
0.006 0.994 0.000
M06.23 Rheumatoid bursitis (Forearm)
0.006 0.994 0.000
M06.22 Rheumatoid bursitis (Upper arm)
0.006 0.994 0.000
M06.21 Rheumatoid bursitis (Shoulder region)
0.006 0.994 0.000
M06.20 Rheumatoid bursitis (Multiple sites)
0.006 0.994 0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.006 0.994 0.000
M06.88 Other specified rheumatoid arthritis (Other)
0.006 0.994 0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.006 0.994 0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.006 0.994 0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.006 0.994 0.000
M06.84 Other specified rheumatoid arthritis (Hand)
0.006 0.994 0.000
M06.83 Other specified rheumatoid arthritis (Forearm)
0.006 0.994 0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.006 0.994 0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.006 0.994 0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.006 0.994 0.000
I36 Nonrheumatic tricuspid valve disorders
0.006 0.994 0.000
C57.0 Fallopian tube
0.006 0.994 0.000
I46.0 Cardiac arrest with successful resuscitation
0.006 0.994 0.000
I38 Endocarditis, valve unspecified
0.006 0.994 0.000
I77.6 Arteritis, unspecified
0.006 0.994 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.006 0.994 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.006 0.994 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.006 0.994 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.006 0.994 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.006 0.994 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.006 0.994 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.006 0.994 0.000
M54.39 Sciatica (Site unspecified)
0.006 0.994 0.000
M40-M43 Deforming dorsopathies
0.006 0.994 0.000
I42.0 Dilated cardiomyopathy
0.006 0.994 0.000
I45.9 Conduction disorder, unspecified
0.006 0.994 0.000
I51 Complications and ill-defined descriptions of heart disease
0.006 0.994 0.000
I72.9 Aneurysm of unspecified site
0.006 0.994 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.006 0.994 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.006 0.994 0.000
I72.2 Aneurysm of renal artery
0.006 0.994 0.000
I72.1 Aneurysm of artery of upper extremity
0.006 0.994 0.000
I72.0 Aneurysm of carotid artery
0.006 0.994 0.000
C53.9 Cervix uteri, unspecified
0.006 0.994 0.000
I46.1 Sudden cardiac death, so described
0.006 0.994 0.000
I51.9 Heart disease, unspecified
0.006 0.994 0.000
I71.0 Dissection of aorta [any part]
0.006 0.994 0.000
M05.8 Other seropositive rheumatoid arthritis
0.006 0.994 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.006 0.994 0.000
M05.2 Rheumatoid vasculitis
0.006 0.994 0.000
M05.1 Rheumatoid lung disease
0.006 0.994 0.000
M05.0 Felty's syndrome
0.006 0.994 0.000
M14 Arthropathies in other diseases classified elsewhere
0.006 0.994 0.000
I30 Acute pericarditis
0.006 0.994 0.000
M12 Other specific arthropathies
0.006 0.994 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.006 0.994 0.000
M08 Juvenile arthritis
0.006 0.994 0.000
M41.86 Other forms of scoliosis (Lumbar region)
0.006 0.994 0.000
M41.89 Other forms of scoliosis (Site unspecified)
0.006 0.994 0.000
M41.88 Other forms of scoliosis (Sacral and sacrococcygeal region)
0.006 0.994 0.000
M41.87 Other forms of scoliosis (Lumbosacral region)
0.006 0.994 0.000
M41.85 Other forms of scoliosis (Thoracolumbar region)
0.006 0.994 0.000
M41.84 Other forms of scoliosis (Thoracic region)
0.006 0.994 0.000
M41.83 Other forms of scoliosis (Cervicothoracic region)
0.006 0.994 0.000
M41.82 Other forms of scoliosis (Cervical region)
0.006 0.994 0.000
M41.81 Other forms of scoliosis (Occipito-atlanto-axial region)
0.006 0.994 0.000
M41.80 Other forms of scoliosis (Multiple sites in spine)
0.006 0.994 0.000
M41.09 Infantile idiopathic scoliosis (Site unspecified)
0.005 0.994 0.000
M41.08 Infantile idiopathic scoliosis (Sacral and sacrococcygeal region)
0.005 0.994 0.000
M41.07 Infantile idiopathic scoliosis (Lumbosacral region)
0.005 0.994 0.000
M41.06 Infantile idiopathic scoliosis (Lumbar region)
0.005 0.994 0.000
M41.05 Infantile idiopathic scoliosis (Thoracolumbar region)
0.005 0.994 0.000
M41.04 Infantile idiopathic scoliosis (Thoracic region)
0.005 0.994 0.000
M41.03 Infantile idiopathic scoliosis (Cervicothoracic region)
0.005 0.994 0.000
M41.02 Infantile idiopathic scoliosis (Cervical region)
0.005 0.994 0.000
M41.01 Infantile idiopathic scoliosis (Occipito-atlanto-axial region)
0.005 0.994 0.000
M41.00 Infantile idiopathic scoliosis (Multiple sites in spine)
0.005 0.994 0.000
M41.19 Juvenile idiopathic scoliosis (Site unspecified)
0.005 0.994 0.000
M41.18 Juvenile idiopathic scoliosis (Sacral and sacrococcygeal region)
0.005 0.994 0.000
M41.17 Juvenile idiopathic scoliosis (Lumbosacral region)
0.005 0.994 0.000
M41.16 Juvenile idiopathic scoliosis (Lumbar region)
0.005 0.994 0.000
M41.15 Juvenile idiopathic scoliosis (Thoracolumbar region)
0.005 0.994 0.000
M41.14 Juvenile idiopathic scoliosis (Thoracic region)
0.005 0.994 0.000
M41.13 Juvenile idiopathic scoliosis (Cervicothoracic region)
0.005 0.994 0.000
M41.12 Juvenile idiopathic scoliosis (Cervical region)
0.005 0.994 0.000
M41.11 Juvenile idiopathic scoliosis (Occipito-atlanto-axial region)
0.005 0.994 0.000
M41.10 Juvenile idiopathic scoliosis (Multiple sites in spine)
0.005 0.994 0.000
M41.29 Other idiopathic scoliosis (Site unspecified)
0.005 0.994 0.000
M41.28 Other idiopathic scoliosis (Sacral and sacrococcygeal region)
0.005 0.994 0.000
M41.27 Other idiopathic scoliosis (Lumbosacral region)
0.005 0.994 0.000
M41.26 Other idiopathic scoliosis (Lumbar region)
0.005 0.994 0.000
M41.25 Other idiopathic scoliosis (Thoracolumbar region)
0.005 0.994 0.000
M41.24 Other idiopathic scoliosis (Thoracic region)
0.005 0.994 0.000
M41.23 Other idiopathic scoliosis (Cervicothoracic region)
0.005 0.994 0.000
M41.22 Other idiopathic scoliosis (Cervical region)
0.005 0.994 0.000
M41.21 Other idiopathic scoliosis (Occipito-atlanto-axial region)
0.005 0.994 0.000
M41.20 Other idiopathic scoliosis (Multiple sites in spine)
0.005 0.994 0.000
M41.39 Thoracogenic scoliosis-Site unspe
0.005 0.994 0.000
M41.38 Thoracogenic scoliosis-Sacral/sacrococ
0.005 0.994 0.000
M41.37 Thoracogenic scoliosis-Lumbosacral
0.005 0.994 0.000
M41.36 Thoracogenic scoliosis-Lumbar
0.005 0.994 0.000
M41.35 Thoracogenic scoliosis (Thoracolumbar region)
0.005 0.994 0.000
M41.34 Thoracogenic scoliosis (Thoracic region)
0.005 0.994 0.000
M41.33 Thoracogenic scoliosis (Cervicothoracic region)
0.005 0.994 0.000
M41.32 Thoracogenic scoliosis-Cervical
0.005 0.994 0.000
M41.31 Thoracogenic scoliosis-Occipit-atl-axl
0.005 0.994 0.000
M41.30 Thoracogenic scoliosis (Multiple sites in spine)
0.005 0.994 0.000
M41.49 Neuromuscular scoliosis (Site unspecified)
0.005 0.994 0.000
M41.48 Neuromuscular scoliosis (Sacral and sacrococcygeal region)
0.005 0.994 0.000
M41.47 Neuromuscular scoliosis (Lumbosacral region)
0.005 0.994 0.000
M41.46 Neuromuscular scoliosis (Lumbar region)
0.005 0.994 0.000
M41.45 Neuromuscular scoliosis (Thoracolumbar region)
0.005 0.994 0.000
M41.44 Neuromuscular scoliosis (Thoracic region)
0.005 0.994 0.000
M41.43 Neuromuscular scoliosis (Cervicothoracic region)
0.005 0.994 0.000
M41.42 Neuromuscular scoliosis (Cervical region)
0.005 0.994 0.000
M41.41 Neuromuscular scoliosis (Occipito-atlanto-axial region)
0.005 0.994 0.000
M41.40 Neuromuscular scoliosis (Multiple sites in spine)
0.005 0.994 0.000
M41.59 Other secondary scoliosis (Site unspecified)
0.005 0.994 0.000
M41.58 Other secondary scoliosis (Sacral and sacrococcygeal region)
0.005 0.994 0.000
M41.57 Other secondary scoliosis (Lumbosacral region)
0.005 0.994 0.000
M41.56 Other secondary scoliosis (Lumbar region)
0.005 0.994 0.000
M41.55 Other secondary scoliosis (Thoracolumbar region)
0.005 0.994 0.000
M41.54 Other secondary scoliosis (Thoracic region)
0.005 0.994 0.000
M41.53 Other secondary scoliosis (Cervicothoracic region)
0.005 0.994 0.000
M41.52 Other secondary scoliosis (Cervical region)
0.005 0.994 0.000
M41.51 Other secondary scoliosis (Occipito-atlanto-axial region)
0.005 0.994 0.000
M41.50 Other secondary scoliosis (Multiple sites in spine)
0.005 0.994 0.000
M06.39 Rheumatoid nodule (Site unspecified)
0.005 0.994 0.000
M06.38 Rheumatoid nodule (Other)
0.005 0.994 0.000
M06.36 Rheumatoid nodule (Lower leg)
0.005 0.994 0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.005 0.994 0.000
M06.33 Rheumatoid nodule (Forearm)
0.005 0.994 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.005 0.994 0.000
M06.31 Rheumatoid nodule (Shoulder region)
0.005 0.994 0.000
M06.30 Rheumatoid nodule (Multiple sites)
0.005 0.994 0.000
C57.9 Female genital organ, unspecified
0.006 0.994 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.005 0.994 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.005 0.994 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.005 0.994 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.005 0.994 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.005 0.994 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.005 0.994 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.005 0.994 0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.005 0.994 0.000
M06.46 Inflammatory polyarthropathy (Lower leg)
0.005 0.994 0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.005 0.994 0.000
M06.44 Inflammatory polyarthropathy (Hand)
0.005 0.994 0.000
M06.43 Inflammatory polyarthropathy (Forearm)
0.005 0.994 0.000
M06.42 Inflammatory polyarthropathy (Upper arm)
0.005 0.994 0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.005 0.994 0.000
M06.37 Rheumatoid nodule (Ankle and foot)
0.005 0.994 0.000
I72.8 Aneurysm of other specified arteries
0.005 0.994 0.000
M06.08 Seronegative rheumatoid arthritis (Other)
0.005 0.994 0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.005 0.994 0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.005 0.994 0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.005 0.994 0.000
M06.04 Seronegative rheumatoid arthritis (Hand)
0.005 0.994 0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.005 0.994 0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.005 0.994 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.005 0.994 0.000
M13 Other arthritis
0.006 0.994 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.005 0.994 0.000
M11 Other crystal arthropathies
0.005 0.994 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.005 0.995 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.005 0.995 0.000
I37.9 Pulmonary valve disorder, unspecified
0.005 0.995 0.000
I37.8 Other pulmonary valve disorders
0.005 0.995 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.005 0.995 0.000
I37.0 Pulmonary valve stenosis
0.005 0.995 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.005 0.995 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.005 0.995 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.005 0.995 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.005 0.995 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.005 0.995 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.005 0.995 0.000
I40.9 Acute myocarditis, unspecified
0.005 0.995 0.000
I40.8 Other acute myocarditis
0.005 0.995 0.000
I40.1 Isolated myocarditis
0.005 0.995 0.000
I40.0 Infective myocarditis
0.005 0.995 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.005 0.995 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.005 0.995 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.005 0.995 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.005 0.995 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.005 0.995 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.005 0.995 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.005 0.995 0.000
I48.4 Atypical atrial flutter
0.005 0.995 0.000
I48.3 Typical atrial flutter
0.005 0.995 0.000
I48.2 Chronic atrial fibrillation
0.005 0.995 0.000
I48.1 Persistent atrial fibrillation
0.005 0.995 0.000
I48.0 Paroxysmal atrial fibrillation
0.005 0.995 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.005 0.995 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.005 0.995 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.005 0.995 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.005 0.995 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.005 0.995 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.005 0.995 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.005 0.995 0.000
I37.1 Pulmonary valve insufficiency
0.005 0.995 0.000
C58 Malignant neoplasm of placenta
0.005 0.995 0.000
M54.3 Sciatica
0.005 0.995 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.005 0.995 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.005 0.995 0.000
C52 Malignant neoplasm of vagina
0.005 0.995 0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.005 0.995 0.000
M54.4 Lumbago with sciatica
0.005 0.995 0.000
I47 Paroxysmal tachycardia
0.005 0.995 0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.005 0.995 0.000
I79.1 Aortitis in diseases classified elsewhere
0.005 0.995 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.005 0.995 0.000
I49.0 Ventricular fibrillation and flutter
0.005 0.995 0.000
C57.8 Overlapping lesion of female genital organs
0.005 0.995 0.000
C57.7 Other specified female genital organs
0.005 0.995 0.000
C57.4 Uterine adnexa, unspecified
0.005 0.995 0.000
C57.3 Parametrium
0.005 0.995 0.000
C57.2 Round ligament
0.005 0.995 0.000
C57.1 Broad ligament
0.005 0.995 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.005 0.995 0.000
I73 Other peripheral vascular diseases
0.005 0.995 0.000
I51.6 Cardiovascular disease, unspecified
0.005 0.995 0.000
I72.3 Aneurysm of iliac artery
0.005 0.995 0.000
I45.2 Bifascicular block
0.005 0.995 0.000
M06.34 Rheumatoid nodule (Hand)
0.005 0.995 0.000
M07 Psoriatic and enteropathic arthropathies
0.005 0.995 0.000
C53.8 Overlapping lesion of cervix uteri
0.005 0.995 0.000
C53.1 Exocervix
0.005 0.995 0.000
C53.0 Endocervix
0.005 0.995 0.000
M13.0 Polyarthritis, unspecified
0.005 0.995 0.000
I49.8 Other specified cardiac arrhythmias
0.005 0.995 0.000
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.005 0.995 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.005 0.995 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.005 0.995 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.005 0.995 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.005 0.995 0.000
I42.5 Other restrictive cardiomyopathy
0.005 0.995 0.000
I42.4 Endocardial fibroelastosis
0.005 0.995 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.005 0.995 0.000
M40 Kyphosis and lordosis
0.005 0.995 0.000
I42.2 Other hypertrophic cardiomyopathy
0.005 0.995 0.000
M54 Dorsalgia
0.005 0.995 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.005 0.995 0.000
M81.9 Osteoporosis, unspecified
0.005 0.995 0.000
M13.8 Other specified arthritis
0.005 0.995 0.000
M42 Spinal osteochondrosis
0.005 0.995 0.000
I42.9 Cardiomyopathy, unspecified
0.005 0.995 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.005 0.995 0.000
C51 Malignant neoplasm of vulva
0.005 0.995 0.000
I44 Atrioventricular and left bundle-branch block
0.005 0.995 0.000
I31 Other diseases of pericardium
0.005 0.995 0.000
I51.5 Myocardial degeneration
0.005 0.995 0.000
I51.4 Myocarditis, unspecified
0.005 0.995 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.005 0.995 0.000
N36.8 Other specified disorders of urethra
0.000 0.995 0.005
M81.98 Osteoporosis, unspecified (Other)
0.005 0.995 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.005 0.995 0.000
M80-M85 Disorders of bone density and structure
0.005 0.995 0.000
M14.6 Neuropathic arthropathy
0.004 0.995 0.000
M81 Osteoporosis without pathological fracture
0.005 0.995 0.000
M05.09 Felty's syndrome (Site unspecified)
0.004 0.995 0.000
M05.08 Felty's syndrome (Other)
0.004 0.995 0.000
M05.07 Felty's syndrome (Ankle and foot)
0.004 0.995 0.000
M05.06 Felty's syndrome (Lower leg)
0.004 0.995 0.000
M05.05 Felty's syndrome (Pelvic region and thigh)
0.004 0.995 0.000
M05.04 Felty's syndrome (Hand)
0.004 0.995 0.000
M05.03 Felty's syndrome (Forearm)
0.004 0.995 0.000
M05.02 Felty's syndrome (Upper arm)
0.004 0.995 0.000
M05.01 Felty's syndrome (Shoulder region)
0.004 0.995 0.000
M05.00 Felty's syndrome (Multiple sites)
0.004 0.995 0.000
M05.19 Rheumatoid lung disease (Site unspecified)
0.004 0.995 0.000
M05.18 Rheumatoid lung disease (Other)
0.004 0.995 0.000
M05.17 Rheumatoid lung disease (Ankle and foot)
0.004 0.995 0.000
M05.16 Rheumatoid lung disease (Lower leg)
0.004 0.995 0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.004 0.995 0.000
M05.14 Rheumatoid lung disease (Hand)
0.004 0.995 0.000
M05.13 Rheumatoid lung disease (Forearm)
0.004 0.995 0.000
M05.12 Rheumatoid lung disease (Upper arm)
0.004 0.995 0.000
M05.11 Rheumatoid lung disease (Shoulder region)
0.004 0.995 0.000
M05.10 Rheumatoid lung disease (Multiple sites)
0.004 0.995 0.000
M05.29 Rheumatoid vasculitis (Site unspecified)
0.004 0.995 0.000
M05.28 Rheumatoid vasculitis (Other)
0.004 0.995 0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.004 0.995 0.000
M05.26 Rheumatoid vasculitis (Lower leg)
0.004 0.995 0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.004 0.995 0.000
M05.24 Rheumatoid vasculitis (Hand)
0.004 0.995 0.000
M05.23 Rheumatoid vasculitis (Forearm)
0.004 0.995 0.000
M05.22 Rheumatoid vasculitis (Upper arm)
0.004 0.995 0.000
M05.21 Rheumatoid vasculitis (Shoulder region)
0.004 0.995 0.000
M05.20 Rheumatoid vasculitis (Multiple sites)
0.004 0.995 0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.004 0.995 0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.004 0.995 0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.004 0.995 0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.004 0.995 0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.004 0.995 0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.004 0.995 0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.004 0.995 0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.004 0.995 0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.004 0.995 0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.004 0.995 0.000
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.004 0.995 0.000
M05.88 Other seropositive rheumatoid arthritis (Other)
0.004 0.995 0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.004 0.995 0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.004 0.995 0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.004 0.995 0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.004 0.995 0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.004 0.995 0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.004 0.995 0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.004 0.995 0.000
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.004 0.995 0.000
M14.8 Arthropathies in other specified diseases classified elsewhere
0.004 0.995 0.000
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.004 0.995 0.000
M14.4 Arthropathy in amyloidosis
0.004 0.995 0.000
M14.3 Lipoid dermatoarthritis
0.004 0.995 0.000
M14.2 Diabetic arthropathy
0.004 0.995 0.000
M14.1 Crystal arthropathy in other metabolic disorders
0.004 0.995 0.000
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.004 0.995 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.004 0.995 0.000
M54.2 Cervicalgia
0.004 0.995 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.004 0.995 0.000
I30.8 Other forms of acute pericarditis
0.004 0.996 0.000
I30.1 Infective pericarditis
0.004 0.996 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.004 0.996 0.000
M08.9 Juvenile arthritis, unspecified
0.004 0.996 0.000
M08.8 Other juvenile arthritis
0.004 0.996 0.000
M08.4 Pauciarticular juvenile arthritis
0.004 0.996 0.000
M08.3 Juvenile polyarthritis (seronegative)
0.004 0.996 0.000
M08.2 Juvenile arthritis with systemic onset
0.004 0.996 0.000
M08.1 Juvenile ankylosing spondylitis
0.004 0.996 0.000
M08.0 Juvenile rheumatoid arthritis
0.004 0.996 0.000
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.004 0.996 0.000
M09.2 Juvenile arthritis in ulcerative colitis
0.004 0.996 0.000
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.004 0.996 0.000
M09.0 Juvenile arthritis in psoriasis
0.004 0.996 0.000
M12.8 Other specific arthropathies, not elsewhere classified
0.004 0.996 0.000
M12.5 Traumatic arthropathy
0.004 0.996 0.000
M12.4 Intermittent hydrarthrosis
0.004 0.996 0.000
M12.3 Palindromic rheumatism
0.004 0.996 0.000
M12.2 Villonodular synovitis (pigmented)
0.004 0.996 0.000
M12.1 Kaschin-Beck disease
0.004 0.996 0.000
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.004 0.996 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.004 0.996 0.000
I51.8 Other ill-defined heart diseases
0.004 0.996 0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.004 0.996 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.004 0.996 0.000
M47.82 Other spondylosis (Cervical region)
0.004 0.996 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.004 0.996 0.000
M54.37 Sciatica (Lumbosacral region)
0.004 0.996 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.004 0.996 0.000
M13.1 Monoarthritis, not elsewhere classified
0.004 0.996 0.000
M10 Gout
0.004 0.996 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.004 0.996 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.004 0.996 0.000
M11.9 Crystal arthropathy, unspecified
0.004 0.996 0.000
M11.8 Other specified crystal arthropathies
0.004 0.996 0.000
M11.1 Familial chondrocalcinosis
0.004 0.996 0.000
M11.0 Hydroxyapatite deposition disease
0.004 0.996 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.004 0.996 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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