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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11216185
log Bayes Factor = 0.968028
Chromosome 11   position 116,782,974  (GRCh37) Explore rs11216185 on Ensembl!
Variant rs11216185 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XV Pregnancy, childbirth and the puerperium
0.000 0.418 0.582
O00-O08 Pregnancy with abortive outcome
0.000 0.429 0.571
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.000 0.441 0.559
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.000 0.445 0.555
O20-O29 Other maternal disorders predominantly related to pregnancy
0.000 0.446 0.554
O36 Maternal care for other known or suspected foetal problems
0.000 0.456 0.544
O03 Spontaneous abortion
0.000 0.458 0.542
O94-O99 Other obstetric conditions, not elsewhere classified
0.000 0.469 0.531
O47 False labour
0.000 0.474 0.526
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.000 0.475 0.525
O04 Medical abortion
0.000 0.475 0.525
O03.4 Incomplete, without complication
0.000 0.482 0.518
O80-O84 Delivery
0.000 0.482 0.518
O36.8 Maternal care for other specified foetal problems
0.000 0.490 0.510
O47.1 False labour at or after 37 completed weeks of gestation
0.000 0.495 0.505
O16 Unspecified maternal hypertension
0.000 0.501 0.499
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.000 0.506 0.494
O04.9 Complete or unspecified, without complication
0.000 0.509 0.491
O20 Haemorrhage in early pregnancy
0.000 0.516 0.484
O82 Single delivery by Caesarean section
0.000 0.522 0.478
O23 Infections of genito-urinary tract in pregnancy
0.000 0.524 0.476
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.000 0.528 0.472
I30-I52 Other forms of heart disease
0.470 0.530 0.000
I42 Cardiomyopathy
0.469 0.531 0.000
I50 Heart failure
0.464 0.536 0.000
O36.5 Maternal care for poor foetal growth
0.000 0.536 0.464
I51 Complications and ill-defined descriptions of heart disease
0.462 0.538 0.000
I42.9 Cardiomyopathy, unspecified
0.460 0.540 0.000
O36.9 Maternal care for foetal problem, unspecified
0.000 0.540 0.460
O41 Other disorders of amniotic fluid and membranes
0.000 0.545 0.455
O36.6 Maternal care for excessive foetal growth
0.000 0.552 0.448
O02 Other abnormal products of conception
0.000 0.554 0.446
I42.0 Dilated cardiomyopathy
0.438 0.562 0.000
I51.8 Other ill-defined heart diseases
0.432 0.568 0.000
Z72.0 Tobacco use
0.431 0.569 0.000
O24 Diabetes mellitus in pregnancy
0.000 0.569 0.431
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.000 0.571 0.429
O82.0 Delivery by elective Caesarean section
0.000 0.571 0.429
O47.9 False labour, unspecified
0.000 0.571 0.429
I49 Other cardiac arrhythmias
0.427 0.573 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.000 0.573 0.427
I50.1 Left ventricular failure
0.425 0.575 0.000
I50.9 Heart failure, unspecified
0.423 0.577 0.000
O20.9 Haemorrhage in early pregnancy, unspecified
0.000 0.580 0.420
O40 Polyhydramnios
0.000 0.580 0.420
O85-O92 Complications predominantly related to the puerperium
0.000 0.582 0.418
I44 Atrioventricular and left bundle-branch block
0.416 0.584 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.000 0.584 0.416
O21 Excessive vomiting in pregnancy
0.000 0.585 0.415
O08 Complications following abortion and ectopic and molar pregnancy
0.000 0.591 0.409
O07 Failed attempted abortion
0.000 0.591 0.409
O06 Unspecified abortion
0.000 0.591 0.409
O05 Other abortion
0.000 0.591 0.409
O01 Hydatidiform mole
0.000 0.591 0.409
O23.4 Unspecified infection of urinary tract in pregnancy
0.000 0.593 0.407
O03.9 Complete or unspecified, without complication
0.000 0.594 0.406
I50.0 Congestive heart failure
0.405 0.595 0.000
I51.9 Heart disease, unspecified
0.402 0.598 0.000
O15 Eclampsia
0.000 0.599 0.401
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.000 0.599 0.401
O82.1 Delivery by emergency Caesarean section
0.000 0.601 0.399
O45 Premature separation of placenta [abruptio placentae]
0.000 0.602 0.398
O33 Maternal care for known or suspected disproportion
0.000 0.602 0.398
O31 Complications specific to multiple gestation
0.000 0.602 0.398
O29 Complications of anaesthesia during pregnancy
0.000 0.602 0.397
O28 Abnormal findings on antenatal screening of mother
0.000 0.602 0.397
O22 Venous complications in pregnancy
0.000 0.602 0.397
O25 Malnutrition in pregnancy
0.000 0.602 0.397
I49.9 Cardiac arrhythmia, unspecified
0.395 0.605 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.000 0.610 0.390
O36.3 Maternal care for signs of foetal hypoxia
0.000 0.610 0.390
O36.2 Maternal care for hydrops foetalis
0.000 0.610 0.390
O36.1 Maternal care for other isoimmunisation
0.000 0.610 0.390
O03.8 Complete or unspecified, with other and unspecified complications
0.000 0.612 0.388
O03.7 Complete or unspecified, complicated by embolism
0.000 0.612 0.388
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.612 0.388
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.612 0.388
O03.3 Incomplete, with other and unspecified complications
0.000 0.612 0.388
O03.2 Incomplete, complicated by embolism
0.000 0.612 0.388
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.612 0.388
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.612 0.388
I49.4 Other and unspecified premature depolarisation
0.388 0.612 0.000
I51.6 Cardiovascular disease, unspecified
0.387 0.613 0.000
O04.4 Incomplete, without complication
0.000 0.619 0.381
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.000 0.619 0.380
O97 Death from sequelae of direct obstetric causes
0.000 0.619 0.380
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.000 0.619 0.380
O95 Obstetric death of unspecified cause
0.000 0.619 0.380
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.000 0.619 0.380
I38 Endocarditis, valve unspecified
0.380 0.620 0.000
O30 Multiple gestation
0.000 0.620 0.380
O41.0 Oligohydramnios
0.000 0.623 0.377
O04.8 Complete or unspecified, with other and unspecified complications
0.000 0.624 0.376
O04.7 Complete or unspecified, complicated by embolism
0.000 0.624 0.376
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.624 0.376
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.624 0.376
O04.3 Incomplete, with other and unspecified complications
0.000 0.624 0.376
O04.2 Incomplete, complicated by embolism
0.000 0.624 0.376
O04.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.624 0.376
O04.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.624 0.376
I42.8 Other cardiomyopathies
0.375 0.625 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.000 0.628 0.372
O84 Multiple delivery
0.000 0.628 0.371
O83 Other assisted single delivery
0.000 0.628 0.371
O81 Single delivery by forceps and vacuum extractor
0.000 0.628 0.371
O20.8 Other haemorrhage in early pregnancy
0.000 0.631 0.369
O42 Premature rupture of membranes
0.000 0.632 0.368
O23.5 Infections of the genital tract in pregnancy
0.000 0.632 0.368
I36 Nonrheumatic tricuspid valve disorders
0.367 0.633 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.000 0.633 0.367
I51.7 Cardiomegaly
0.365 0.635 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.635 0.365
O26.8 Other specified pregnancy-related conditions
0.000 0.640 0.360
O35 Maternal care for known or suspected foetal abnormality and damage
0.000 0.640 0.360
O20.0 Threatened abortion
0.000 0.644 0.356
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium
0.000 0.646 0.354
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
0.000 0.646 0.354
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.000 0.646 0.354
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.000 0.646 0.354
O00 Ectopic pregnancy
0.000 0.648 0.352
I44.0 Atrioventricular block, first degree
0.352 0.648 0.000
O80 Single spontaneous delivery
0.000 0.649 0.351
O36.4 Maternal care for intra-uterine death
0.000 0.650 0.349
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
0.000 0.651 0.349
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.000 0.653 0.347
O34 Maternal care for known or suspected abnormality of pelvic organs
0.000 0.654 0.346
O02.1 Missed abortion
0.000 0.655 0.345
I42.6 Alcoholic cardiomyopathy
0.344 0.656 0.000
O82.9 Delivery by Caesarean section, unspecified
0.000 0.657 0.343
O82.8 Other single delivery by Caesarean section
0.000 0.657 0.343
O82.2 Delivery by Caesarean hysterectomy
0.000 0.657 0.343
O44 Placenta praevia
0.000 0.657 0.343
O24.4 Diabetes mellitus arising in pregnancy
0.000 0.658 0.342
O12.0 Gestational oedema
0.000 0.658 0.342
O23.9 Other and unspecified genito-urinary tract infection in pregnancy
0.000 0.658 0.341
O23.3 Infections of other parts of urinary tract in pregnancy
0.000 0.658 0.341
O23.2 Infections of urethra in pregnancy
0.000 0.658 0.341
O23.1 Infections of bladder in pregnancy
0.000 0.658 0.341
O23.0 Infections of kidney in pregnancy
0.000 0.658 0.341
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
0.000 0.661 0.339
I52 Other heart disorders in diseases classified elsewhere
0.337 0.663 0.000
I48 Atrial fibrillation and flutter
0.337 0.663 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.337 0.663 0.000
I41 Myocarditis in diseases classified elsewhere
0.337 0.663 0.000
I40 Acute myocarditis
0.337 0.663 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.337 0.663 0.000
I32 Pericarditis in diseases classified elsewhere
0.337 0.663 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.336 0.663 0.000
I42.5 Other restrictive cardiomyopathy
0.336 0.663 0.000
I42.4 Endocardial fibroelastosis
0.336 0.663 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.336 0.663 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.000 0.664 0.335
O02.0 Blighted ovum and nonhydatidiform mole
0.000 0.665 0.335
I44.3 Other and unspecified atrioventricular block
0.332 0.668 0.000
I51.5 Myocardial degeneration
0.331 0.669 0.000
I51.4 Myocarditis, unspecified
0.331 0.669 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.331 0.669 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.331 0.669 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.331 0.669 0.000
O21.0 Mild hyperemesis gravidarum
0.000 0.670 0.329
I30 Acute pericarditis
0.328 0.672 0.000
O43 Placental disorders
0.000 0.672 0.327
O90 Complications of the puerperium, not elsewhere classified
0.000 0.673 0.326
O41.9 Disorder of amniotic fluid and membranes, unspecified
0.000 0.674 0.326
O41.1 Infection of amniotic sac and membranes
0.000 0.674 0.326
I49.5 Sick sinus syndrome
0.325 0.674 0.000
I44.1 Atrioventricular block, second degree
0.323 0.677 0.000
O02.9 Abnormal product of conception, unspecified
0.000 0.680 0.320
O02.8 Other specified abnormal products of conception
0.000 0.680 0.320
I51.0 Cardiac septal defect, acquired
0.314 0.685 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.312 0.688 0.000
O24.9 Diabetes mellitus in pregnancy, unspecified
0.000 0.691 0.309
O24.3 Pre-existing diabetes mellitus, unspecified
0.000 0.691 0.309
O24.2 Pre-existing malnutrition-related diabetes mellitus
0.000 0.691 0.309
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent
0.000 0.691 0.309
O24.0 Pre-existing diabetes mellitus, insulin-dependent
0.000 0.691 0.309
I44.2 Atrioventricular block, complete
0.309 0.691 0.000
O47.0 False labour before 37 completed weeks of gestation
0.000 0.692 0.308
O12.2 Gestational oedema with proteinuria
0.000 0.692 0.308
I44.7 Left bundle-branch block, unspecified
0.308 0.692 0.000
I49.2 Junctional premature depolarisation
0.306 0.694 0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
0.000 0.694 0.306
O26.6 Liver disorders in pregnancy, childbirth and the puerperium
0.000 0.694 0.306
O26.5 Maternal hypotension syndrome
0.000 0.694 0.306
O26.4 Herpes gestationis
0.000 0.694 0.306
O26.3 Retained intra-uterine contraceptive device in pregnancy
0.000 0.694 0.306
O26.2 Pregnancy care of habitual aborter
0.000 0.694 0.306
O26.1 Low weight gain in pregnancy
0.000 0.694 0.306
O26.0 Excessive weight gain in pregnancy
0.000 0.694 0.306
I47 Paroxysmal tachycardia
0.305 0.695 0.000
O12.1 Gestational proteinuria
0.000 0.699 0.301
O92 Other disorders of breast and lactation associated with childbirth
0.000 0.700 0.300
O91 Infections of breast associated with childbirth
0.000 0.700 0.300
O89 Complications of anaesthesia during the puerperium
0.000 0.700 0.300
O88 Obstetric embolism
0.000 0.700 0.300
O87 Venous complications in the puerperium
0.000 0.700 0.300
O85 Puerperal sepsis
0.000 0.700 0.300
I44.5 Left posterior fascicular block
0.298 0.702 0.000
I44.4 Left anterior fascicular block
0.298 0.702 0.000
O21.8 Other vomiting complicating pregnancy
0.000 0.702 0.297
O21.2 Late vomiting of pregnancy
0.000 0.702 0.297
O21.1 Hyperemesis gravidarum with metabolic disturbance
0.000 0.702 0.297
I37 Pulmonary valve disorders
0.297 0.703 0.000
I49.1 Atrial premature depolarisation
0.295 0.705 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.294 0.706 0.000
O01.9 Hydatidiform mole, unspecified
0.000 0.706 0.293
O01.1 Incomplete and partial hydatidiform mole
0.000 0.706 0.293
O01.0 Classical hydatidiform mole
0.000 0.706 0.293
O05.9 Complete or unspecified, without complication
0.000 0.706 0.293
O05.8 Complete or unspecified, with other and unspecified complications
0.000 0.706 0.293
O05.7 Complete or unspecified, complicated by embolism
0.000 0.706 0.293
O05.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.706 0.293
O05.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.706 0.293
O05.4 Incomplete, without complication
0.000 0.706 0.293
O05.3 Incomplete, with other and unspecified complications
0.000 0.706 0.293
O05.2 Incomplete, complicated by embolism
0.000 0.706 0.293
O05.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.706 0.293
O05.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.706 0.293
O06.9 Complete or unspecified, without complication
0.000 0.706 0.293
O06.8 Complete or unspecified, with other and unspecified complications
0.000 0.706 0.293
O06.7 Complete or unspecified, complicated by embolism
0.000 0.706 0.293
O06.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.000 0.706 0.293
O06.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.000 0.706 0.293
O06.4 Incomplete, without complication
0.000 0.706 0.293
O06.3 Incomplete, with other and unspecified complications
0.000 0.706 0.293
O06.2 Incomplete, complicated by embolism
0.000 0.706 0.293
O06.1 Incomplete, complicated by delayed or excessive haemorrhage
0.000 0.706 0.293
O06.0 Incomplete, complicated by genital tract and pelvic infection
0.000 0.706 0.293
O07.9 Other and unspecified failed attempted abortion, without complication
0.000 0.706 0.293
O07.8 Other and unspecified failed attempted abortion, with other and unspecified complications
0.000 0.706 0.293
O07.7 Other and unspecified failed attempted abortion, complicated by embolism
0.000 0.706 0.293
O07.6 Other and unspecified failed attempted abortion, complicated by delayed or excessive haemorrhage
0.000 0.706 0.293
O07.5 Other and unspecified failed attempted abortion, complicated by genital tract and pelvic infection
0.000 0.706 0.293
O07.4 Failed medical abortion, without complication
0.000 0.706 0.293
O07.3 Failed medical abortion, with other and unspecified complications
0.000 0.706 0.293
O07.2 Failed medical abortion, complicated by embolism
0.000 0.706 0.293
O07.1 Failed medical abortion, complicated by delayed or excessive haemorrhage
0.000 0.706 0.293
O07.0 Failed medical abortion, complicated by genital tract and pelvic infection
0.000 0.706 0.293
O08.9 Complication following abortion and ectopic and molar pregnancy, unspecified
0.000 0.706 0.293
O08.8 Other complications following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.7 Other venous complications following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.6 Damage to pelvic organs and tissues following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.5 Metabolic disorders following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.4 Renal failure following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.3 Shock following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.2 Embolism following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.1 Delayed or excessive haemorrhage following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O08.0 Genital tract and pelvic infection following abortion and ectopic and molar pregnancy
0.000 0.706 0.293
O32 Maternal care for known or suspected malpresentation of foetus
0.000 0.710 0.290
O15.9 Eclampsia, unspecified as to time period
0.000 0.712 0.287
O15.2 Eclampsia in the puerperium
0.000 0.712 0.287
O15.1 Eclampsia in labour
0.000 0.712 0.287
O15.0 Eclampsia in pregnancy
0.000 0.712 0.287
O31.8 Other complications specific to multiple gestation
0.000 0.714 0.285
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more
0.000 0.714 0.285
O31.1 Continuing pregnancy after abortion of one foetus or more
0.000 0.714 0.285
O31.0 Papyraceous foetus
0.000 0.714 0.285
O33.9 Maternal care for disproportion, unspecified
0.000 0.714 0.285
O33.8 Maternal care for disproportion of other origin
0.000 0.714 0.285
O33.7 Maternal care for disproportion due to other foetal deformities
0.000 0.714 0.285
O33.6 Maternal care for disproportion due to hydrocephalic foetus
0.000 0.714 0.285
O33.5 Maternal care for disproportion due to unusually large foetus
0.000 0.714 0.285
O33.4 Maternal care for disproportion of mixed maternal and foetal origin
0.000 0.714 0.285
O33.3 Maternal care for disproportion due to outlet contraction of pelvis
0.000 0.714 0.285
O33.2 Maternal care for disproportion due to inlet contraction of pelvis
0.000 0.714 0.285
O33.1 Maternal care for disproportion due to generally contracted pelvis
0.000 0.714 0.285
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones
0.000 0.714 0.285
O45.9 Premature separation of placenta, unspecified
0.000 0.714 0.285
O45.8 Other premature separation of placenta
0.000 0.714 0.285
O45.0 Premature separation of placenta with coagulation defect
0.000 0.714 0.285
O22.9 Venous complication in pregnancy, unspecified
0.000 0.715 0.285
O22.8 Other venous complications in pregnancy
0.000 0.715 0.285
O22.5 Cerebral venous thrombosis in pregnancy
0.000 0.715 0.285
O22.4 Haemorrhoids in pregnancy
0.000 0.715 0.285
O22.3 Deep phlebothrombosis in pregnancy
0.000 0.715 0.285
O22.2 Superficial thrombophlebitis in pregnancy
0.000 0.715 0.285
O22.1 Genital varices in pregnancy
0.000 0.715 0.285
O22.0 Varicose veins of lower extremity in pregnancy
0.000 0.715 0.285
O28.9 Abnormal finding on antenatal screening of mother, unspecified
0.000 0.715 0.285
O28.8 Other abnormal findings on antenatal screening of mother
0.000 0.715 0.285
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother
0.000 0.715 0.285
O28.4 Abnormal radiological finding on antenatal screening of mother
0.000 0.715 0.285
O28.3 Abnormal ultrasonic finding on antenatal screening of mother
0.000 0.715 0.285
O28.2 Abnormal cytological finding on antenatal screening of mother
0.000 0.715 0.285
O28.1 Abnormal biochemical finding on antenatal screening of mother
0.000 0.715 0.285
O28.0 Abnormal haematological finding on antenatal screening of mother
0.000 0.715 0.285
O29.9 Complication of anaesthesia during pregnancy, unspecified
0.000 0.715 0.285
O29.8 Other complications of anaesthesia during pregnancy
0.000 0.715 0.285
O29.6 Failed or difficult intubation during pregnancy
0.000 0.715 0.285
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy
0.000 0.715 0.285
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy
0.000 0.715 0.285
O29.3 Toxic reaction to local anaesthesia during pregnancy
0.000 0.715 0.285
O29.2 Central nervous system complications of anaesthesia during pregnancy
0.000 0.715 0.285
O29.1 Cardiac complications of anaesthesia during pregnancy
0.000 0.715 0.285
O29.0 Pulmonary complications of anaesthesia during pregnancy
0.000 0.715 0.285
O80.0 Spontaneous vertex delivery
0.000 0.715 0.285
I33 Acute and subacute endocarditis
0.282 0.718 0.000
I46 Cardiac arrest
0.279 0.721 0.000
O21.9 Vomiting of pregnancy, unspecified
0.000 0.722 0.277
I49.0 Ventricular fibrillation and flutter
0.276 0.724 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.000 0.724 0.276
O96.9 Death from unspecified obstetric cause
0.000 0.727 0.273
O96.1 Death from indirect obstetric cause
0.000 0.727 0.273
O96.0 Death from direct obstetric cause
0.000 0.727 0.273
O97.9 Death from sequelae of obstetric cause, unspecified
0.000 0.727 0.273
O97.1 Death from sequelae of indirect obstetric cause
0.000 0.727 0.273
O97.0 Death from sequelae of direct obstetric cause
0.000 0.727 0.273
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium
0.000 0.727 0.273
O30.9 Multiple gestation, unspecified
0.000 0.728 0.272
O30.8 Other multiple gestation
0.000 0.728 0.272
O30.2 Quadruplet pregnancy
0.000 0.728 0.272
O30.1 Triplet pregnancy
0.000 0.728 0.272
O48 Prolonged pregnancy
0.000 0.728 0.272
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.000 0.729 0.271
O34.1 Maternal care for tumour of corpus uteri
0.000 0.730 0.269
I34 Nonrheumatic mitral valve disorders
0.269 0.731 0.000
I42.2 Other hypertrophic cardiomyopathy
0.268 0.732 0.000
I49.3 Ventricular premature depolarisation
0.267 0.733 0.000
O81.5 Delivery by combination of forceps and vacuum extractor
0.000 0.733 0.266
O81.4 Vacuum extractor delivery
0.000 0.733 0.266
O81.3 Other and unspecified forceps delivery
0.000 0.733 0.266
O81.2 Mid-cavity forceps with rotation
0.000 0.733 0.266
O81.1 Mid-cavity forceps delivery
0.000 0.733 0.266
O81.0 Low forceps delivery
0.000 0.733 0.266
O83.9 Assisted single delivery, unspecified
0.000 0.733 0.266
O83.8 Other specified assisted single delivery
0.000 0.733 0.266
O83.4 Destructive operation for delivery
0.000 0.733 0.266
O83.3 Delivery of viable foetus in abdominal pregnancy
0.000 0.733 0.266
O83.2 Other manipulation-assisted delivery
0.000 0.733 0.266
O83.1 Other assisted breech delivery
0.000 0.733 0.266
O83.0 Breech extraction
0.000 0.733 0.266
O84.9 Multiple delivery, unspecified
0.000 0.733 0.266
O84.8 Other multiple delivery
0.000 0.733 0.266
O84.2 Multiple delivery, all by Caesarean section
0.000 0.733 0.266
O84.1 Multiple delivery, all by forceps and vacuum extractor
0.000 0.733 0.266
O84.0 Multiple delivery, all spontaneous
0.000 0.733 0.266
O86 Other puerperal infections
0.000 0.734 0.266
O42.2 Premature rupture of membranes, labour delayed by therapy
0.000 0.736 0.264
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.263 0.736 0.000
I36.8 Other nonrheumatic tricuspid valve disorders
0.263 0.736 0.000
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.263 0.736 0.000
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.263 0.736 0.000
O46.8 Other antepartum haemorrhage
0.000 0.736 0.263
O46.0 Antepartum haemorrhage with coagulation defect
0.000 0.736 0.263
O26.9 Pregnancy-related condition, unspecified
0.000 0.737 0.263
I44.6 Other and unspecified fascicular block
0.263 0.737 0.000
O80.8 Other single spontaneous delivery
0.000 0.737 0.262
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.738 0.261
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.738 0.261
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium
0.000 0.738 0.261
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium
0.000 0.738 0.261
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium
0.000 0.738 0.261
O90.8 Other complications of the puerperium, not elsewhere classified
0.000 0.739 0.261
I45 Other conduction disorders
0.260 0.739 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.000 0.742 0.258
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.000 0.742 0.258
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.000 0.742 0.258
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.000 0.742 0.258
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.000 0.742 0.258
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.000 0.742 0.258
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.000 0.742 0.258
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.000 0.742 0.258
O14.2 HELLP syndrome
0.000 0.746 0.254
O14.1 Severe preeclampsia
0.000 0.746 0.254
O14.0 Moderate preeclampsia
0.000 0.746 0.254
O30.0 Twin pregnancy
0.000 0.746 0.254
O00.9 Ectopic pregnancy, unspecified
0.000 0.748 0.252
O00.8 Other ectopic pregnancy
0.000 0.748 0.252
O00.2 Ovarian pregnancy
0.000 0.748 0.252
O00.0 Abdominal pregnancy
0.000 0.748 0.252
O80.1 Spontaneous breech delivery
0.000 0.748 0.252
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.000 0.748 0.252
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.000 0.751 0.249
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.000 0.752 0.248
O34.6 Maternal care for abnormality of vagina
0.000 0.752 0.248
O34.5 Maternal care for other abnormalities of gravid uterus
0.000 0.752 0.248
O34.4 Maternal care for other abnormalities of cervix
0.000 0.752 0.248
O34.3 Maternal care for cervical incompetence
0.000 0.752 0.248
O34.0 Maternal care for congenital malformation of uterus
0.000 0.752 0.248
I08.1 Disorders of both mitral and tricuspid valves
0.246 0.754 0.000
I08 Multiple valve diseases
0.246 0.754 0.000
I32.8 Pericarditis in other diseases classified elsewhere
0.242 0.758 0.000
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.242 0.758 0.000
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.242 0.758 0.000
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.242 0.758 0.000
I39.4 Multiple valve disorders in diseases classified elsewhere
0.242 0.758 0.000
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.242 0.758 0.000
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.242 0.758 0.000
I39.1 Aortic valve disorders in diseases classified elsewhere
0.242 0.758 0.000
I39.0 Mitral valve disorders in diseases classified elsewhere
0.242 0.758 0.000
I40.9 Acute myocarditis, unspecified
0.242 0.758 0.000
I40.8 Other acute myocarditis
0.242 0.758 0.000
I40.1 Isolated myocarditis
0.242 0.758 0.000
I40.0 Infective myocarditis
0.242 0.758 0.000
I41.8 Myocarditis in other diseases classified elsewhere
0.242 0.758 0.000
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.242 0.758 0.000
I41.1 Myocarditis in viral diseases classified elsewhere
0.242 0.758 0.000
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.242 0.758 0.000
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.242 0.758 0.000
I43.2 Cardiomyopathy in nutritional diseases
0.242 0.758 0.000
I43.1 Cardiomyopathy in metabolic diseases
0.242 0.758 0.000
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.242 0.758 0.000
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.242 0.758 0.000
I48.4 Atypical atrial flutter
0.242 0.758 0.000
I48.3 Typical atrial flutter
0.242 0.758 0.000
I48.2 Chronic atrial fibrillation
0.242 0.758 0.000
I48.1 Persistent atrial fibrillation
0.242 0.758 0.000
I48.0 Paroxysmal atrial fibrillation
0.242 0.758 0.000
I52.8 Other heart disorders in other diseases classified elsewhere
0.242 0.758 0.000
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.242 0.758 0.000
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.242 0.758 0.000
I05-I09 Chronic rheumatic heart diseases
0.241 0.759 0.000
I30.1 Infective pericarditis
0.241 0.759 0.000
Chapter IX Diseases of the circulatory system
0.238 0.762 0.000
I30.8 Other forms of acute pericarditis
0.235 0.764 0.000
I30.0 Acute nonspecific idiopathic pericarditis
0.235 0.764 0.000
I47.0 Reentry ventricular arrhythmia
0.235 0.765 0.000
O43.9 Placental disorder, unspecified
0.000 0.765 0.235
O43.2 Morbidly adherent placenta
0.000 0.765 0.235
O43.0 Placental transfusion syndromes
0.000 0.765 0.235
O43.1 Malformation of placenta
0.000 0.765 0.234
O90.9 Complication of the puerperium, unspecified
0.000 0.766 0.234
O90.5 Postpartum thyroiditis
0.000 0.766 0.234
O90.4 Postpartum acute renal failure
0.000 0.766 0.234
O90.3 Cardiomyopathy in the puerperium
0.000 0.766 0.234
O90.2 Haematoma of obstetric wound
0.000 0.766 0.234
O90.1 Disruption of perineal obstetric wound
0.000 0.766 0.234
O90.0 Disruption of Caesarean section wound
0.000 0.766 0.234
O34.8 Maternal care for other abnormalities of pelvic organs
0.000 0.766 0.233
O34.7 Maternal care for abnormality of vulva and perineum
0.000 0.767 0.233
O46.9 Antepartum haemorrhage, unspecified
0.000 0.767 0.233
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.000 0.769 0.231
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
0.000 0.774 0.225
I45.6 Preexcitation syndrome
0.226 0.774 0.000
I08.0 Disorders of both mitral and aortic valves
0.225 0.775 0.000
O44.0 Placenta praevia specified as without haemorrhage
0.000 0.777 0.223
I30.9 Acute pericarditis, unspecified
0.220 0.780 0.000
O44.1 Placenta praevia with haemorrhage
0.000 0.780 0.219
O32.0 Maternal care for unstable lie
0.000 0.781 0.218
I45.3 Trifascicular block
0.216 0.784 0.000
O87.9 Venous complication in the puerperium, unspecified
0.000 0.785 0.215
O87.8 Other venous complications in the puerperium
0.000 0.785 0.215
O87.3 Cerebral venous thrombosis in the puerperium
0.000 0.785 0.215
O87.2 Haemorrhoids in the puerperium
0.000 0.785 0.215
O87.1 Deep phlebothrombosis in the puerperium
0.000 0.785 0.215
O87.0 Superficial thrombophlebitis in the puerperium
0.000 0.785 0.215
O88.8 Other obstetric embolism
0.000 0.785 0.215
O88.3 Obstetric pyaemic and septic embolism
0.000 0.785 0.215
O88.2 Obstetric blood-clot embolism
0.000 0.785 0.215
O88.1 Amniotic fluid embolism
0.000 0.785 0.215
O88.0 Obstetric air embolism
0.000 0.785 0.215
O89.9 Complication of anaesthesia during the puerperium, unspecified
0.000 0.785 0.215
O89.8 Other complications of anaesthesia during the puerperium
0.000 0.785 0.215
O89.6 Failed or difficult intubation during the puerperium
0.000 0.785 0.215
O89.5 Other complications of spinal and epidural anaesthesia during the puerperium
0.000 0.785 0.215
O89.4 Spinal and epidural anaesthesia-induced headache during the puerperium
0.000 0.785 0.215
O89.3 Toxic reaction to local anaesthesia during the puerperium
0.000 0.785 0.215
O89.2 Central nervous system complications of anaesthesia during the puerperium
0.000 0.785 0.215
O89.1 Cardiac complications of anaesthesia during the puerperium
0.000 0.785 0.215
O89.0 Pulmonary complications of anaesthesia during the puerperium
0.000 0.785 0.215
O91.2 Nonpurulent mastitis associated with childbirth
0.000 0.785 0.215
O91.1 Abscess of breast associated with childbirth
0.000 0.785 0.215
O91.0 Infection of nipple associated with childbirth
0.000 0.785 0.215
O92.7 Other and unspecified disorders of lactation
0.000 0.785 0.215
O92.6 Galactorrhoea
0.000 0.785 0.215
O92.5 Suppressed lactation
0.000 0.785 0.215
O92.4 Hypogalactia
0.000 0.785 0.215
O92.3 Agalactia
0.000 0.785 0.215
O92.2 Other and unspecified disorders of breast associated with childbirth
0.000 0.785 0.215
O92.1 Cracked nipple associated with childbirth
0.000 0.785 0.215
O92.0 Retracted nipple associated with childbirth
0.000 0.785 0.215
I37.9 Pulmonary valve disorder, unspecified
0.213 0.787 0.000
I37.8 Other pulmonary valve disorders
0.213 0.787 0.000
I37.2 Pulmonary valve stenosis with insufficiency
0.213 0.787 0.000
I37.0 Pulmonary valve stenosis
0.213 0.787 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.212 0.788 0.000
I46.0 Cardiac arrest with successful resuscitation
0.210 0.790 0.000
O32.2 Maternal care for transverse and oblique lie
0.000 0.791 0.209
O32.9 Maternal care for malpresentation of foetus, unspecified
0.000 0.792 0.208
O32.6 Maternal care for compound presentation
0.000 0.792 0.208
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.000 0.792 0.208
O32.3 Maternal care for face, brow and chin presentation
0.000 0.792 0.208
O14.9 Preeclampsia, unspecified
0.000 0.793 0.207
O42.9 Premature rupture of membranes, unspecified
0.000 0.796 0.204
O34.2 Maternal care due to uterine scar from previous surgery
0.000 0.797 0.203
I47.2 Ventricular tachycardia
0.203 0.797 0.000
I33.9 Acute endocarditis, unspecified
0.202 0.797 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.200 0.800 0.000
I46.1 Sudden cardiac death, so described
0.200 0.800 0.000
I31 Other diseases of pericardium
0.199 0.800 0.000
O32.4 Maternal care for high head at term
0.000 0.802 0.198

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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