TreeWAS – Variant ID: rs11217843

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.9 Glaucoma, unspecified	0.576	0.424	0.000
H40 Glaucoma	0.568	0.432	0.000
H40.2 Primary angle-closure glaucoma	0.563	0.437	0.000
H40.1 Primary open-angle glaucoma	0.529	0.471	0.000
H40.4 Glaucoma secondary to eye inflammation	0.418	0.582	0.000
H40.6 Glaucoma secondary to drugs	0.407	0.592	0.000
H40.3 Glaucoma secondary to eye trauma	0.407	0.592	0.000
H40.8 Other glaucoma	0.397	0.603	0.000
H40.0 Glaucoma suspect	0.358	0.642	0.000
H40.5 Glaucoma secondary to other eye disorders	0.339	0.661	0.000
H40-H42 Glaucoma	0.237	0.763	0.000
H42 Glaucoma in diseases classified elsewhere	0.170	0.830	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.867	0.133
H42.8 Glaucoma in other diseases classified elsewhere	0.122	0.878	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.122	0.878	0.000
S72.0 Fracture of neck of femur	0.000	0.936	0.064
S72.01 Fracture of neck of femur (open)	0.000	0.954	0.046
C79.6 Secondary malignant neoplasm of ovary	0.000	0.959	0.041
C79 Secondary malignant neoplasm of other sites	0.000	0.960	0.040
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.960	0.040
C79.2 Secondary malignant neoplasm of skin	0.000	0.963	0.037
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.966	0.034
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.967	0.033
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.968	0.032
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.972	0.027
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.975	0.025
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.975	0.025
S72 Fracture of femur	0.000	0.986	0.014
N95.2 Postmenopausal atrophic vaginitis	0.000	0.988	0.012
S72.2 Subtrochanteric fracture	0.000	0.990	0.010
S72.7 Multiple fractures of femur	0.000	0.990	0.010
M25.8 Other specified joint disorders	0.010	0.990	0.000
S72.9 Fracture of femur, part unspecified	0.000	0.990	0.010
H52.1 Myopia	0.000	0.990	0.010
M25.86 Other specified joint disorders (Lower leg)	0.010	0.990	0.000
S72.8 Fractures of other parts of femur	0.000	0.990	0.010
S72.3 Fracture of shaft of femur	0.000	0.990	0.010
M25.83 Other specified joint disorders (Forearm)	0.010	0.990	0.000
M25.88 Other specified joint disorders (Other)	0.009	0.991	0.000
S72.4 Fracture of lower end of femur	0.000	0.991	0.009
M25.87 Other specified joint disorders (Ankle and foot)	0.009	0.991	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.008	0.992	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.992	0.008
S72.21 Subtrochanteric fracture (open)	0.000	0.992	0.008
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.992	0.008
S72.71 Multiple fractures of femur (open)	0.000	0.992	0.007
S72.70 Multiple fractures of femur (closed)	0.000	0.992	0.007
M25.89 Other specified joint disorders (Site unspecified)	0.008	0.992	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.008	0.992	0.000
M25.82 Other specified joint disorders (Upper arm)	0.008	0.992	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.008	0.992	0.000
S72.91 Fracture of femur, part unspecified (open)	0.000	0.992	0.007
H72.9 Perforation of tympanic membrane, unspecified	0.008	0.992	0.000
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.993	0.007
S72.1 Pertrochanteric fracture	0.000	0.993	0.007
S72.81 Fractures of other parts of femur (open)	0.000	0.993	0.007
S72.31 Fracture of shaft of femur (open)	0.000	0.993	0.007
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
S72.80 Fractures of other parts of femur (closed)	0.000	0.993	0.007
T46 Poisoning by agents primarily affecting the cardiovascular system	0.007	0.993	0.000
S72.41 Fracture of lower end of femur (open)	0.000	0.993	0.006
S72.30 Fracture of shaft of femur (closed)	0.000	0.993	0.006
M25.84 Other specified joint disorders (Hand)	0.007	0.993	0.000
M25 Other joint disorders, not elsewhere classified	0.007	0.993	0.000
D05.1 Intraductal carcinoma in situ	0.007	0.993	0.000
M25.50 Pain in joint (Multiple sites)	0.006	0.994	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.006	0.994	0.000
M25.51 Pain in joint (Shoulder region)	0.006	0.994	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.006	0.994	0.000
M25.9 Joint disorder, unspecified	0.006	0.994	0.000
M25.5 Pain in joint	0.006	0.994	0.000
M25.3 Other instability of joint	0.006	0.994	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
H72 Perforation of tympanic membrane	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.006	0.994	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.006	0.994	0.000
S72.11 Pertrochanteric fracture (open)	0.000	0.994	0.005
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.000	0.994	0.006
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.005	0.994	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.005	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.005	0.995	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.005	0.995	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.005	0.995	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.995	0.005
M25.0 Haemarthrosis	0.005	0.995	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.005	0.995	0.000
T46.7 Peripheral vasodilators	0.005	0.995	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.005	0.995	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.005	0.995	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.005	0.995	0.000
J32.9 Chronic sinusitis, unspecified	0.005	0.995	0.000
M25.31 Other instability of joint (Shoulder region)	0.005	0.995	0.000
M25.2 Flail joint	0.005	0.995	0.000
M25.1 Fistula of joint	0.005	0.995	0.000
H72.0 Central perforation of tympanic membrane	0.005	0.995	0.000
M25.37 Other instability of joint (Ankle and foot)	0.005	0.995	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.005	0.995	0.000
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
M25.58 Pain in joint (Other)	0.005	0.995	0.000
H72.1 Attic perforation of tympanic membrane	0.005	0.995	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.005	0.995	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.005	0.995	0.000
M25.53 Pain in joint (Forearm)	0.005	0.995	0.000
M25.34 Other instability of joint (Hand)	0.004	0.995	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.004	0.995	0.000
M25.98 Joint disorder, unspecified (Other)	0.004	0.995	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.004	0.995	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.004	0.995	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.004	0.995	0.000
M25.33 Other instability of joint (Forearm)	0.004	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.004	0.995	0.000
M25.39 Other instability of joint (Site unspecified)	0.004	0.996	0.000
M25.38 Other instability of joint (Other)	0.004	0.996	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.004	0.996	0.000
M25.32 Other instability of joint (Upper arm)	0.004	0.996	0.000
M25.30 Other instability of joint (Multiple sites)	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.004	0.996	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
M25.94 Joint disorder, unspecified (Hand)	0.004	0.996	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
T38.1 Thyroid hormones and substitutes	0.004	0.996	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.004	0.996	0.000
T39.0 Salicylates	0.004	0.996	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.004	0.996	0.000
M25.36 Other instability of joint (Lower leg)	0.004	0.996	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.996	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.996	0.000
T44.0 Anticholinesterase agents	0.004	0.996	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.004	0.996	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.996	0.004
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.004	0.996	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.004	0.996	0.000
M25.06 Haemarthrosis (Lower leg)	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
M25.52 Pain in joint (Upper arm)	0.004	0.996	0.000
M25.09 Haemarthrosis (Site unspecified)	0.004	0.996	0.000
M25.08 Haemarthrosis (Other)	0.004	0.996	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.004	0.996	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.004	0.996	0.000
M25.04 Haemarthrosis (Hand)	0.004	0.996	0.000
M25.03 Haemarthrosis (Forearm)	0.004	0.996	0.000
M25.02 Haemarthrosis (Upper arm)	0.004	0.996	0.000
M25.01 Haemarthrosis (Shoulder region)	0.004	0.996	0.000
M25.00 Haemarthrosis (Multiple sites)	0.004	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.000	0.996	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.996	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.004	0.996	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.996	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.004	0.996	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M25.19 Fistula of joint (Site unspecified)	0.004	0.996	0.000
M25.18 Fistula of joint (Other)	0.004	0.996	0.000
M25.17 Fistula of joint (Ankle and foot)	0.004	0.996	0.000
M25.16 Fistula of joint (Lower leg)	0.004	0.996	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.004	0.996	0.000
M25.14 Fistula of joint (Hand)	0.004	0.996	0.000
M25.13 Fistula of joint (Forearm)	0.004	0.996	0.000
M25.12 Fistula of joint (Upper arm)	0.004	0.996	0.000
M25.11 Fistula of joint (Shoulder region)	0.004	0.996	0.000
M25.10 Fistula of joint (Multiple sites)	0.004	0.996	0.000
M25.29 Flail joint (Site unspecified)	0.004	0.996	0.000
M25.28 Flail joint (Other)	0.004	0.996	0.000
M25.27 Flail joint (Ankle and foot)	0.004	0.996	0.000
M25.26 Flail joint (Lower leg)	0.004	0.996	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.004	0.996	0.000
M25.24 Flail joint (Hand)	0.004	0.996	0.000
M25.23 Flail joint (Forearm)	0.004	0.996	0.000
M25.22 Flail joint (Upper arm)	0.004	0.996	0.000
M25.21 Flail joint (Shoulder region)	0.004	0.996	0.000
M25.20 Flail joint (Multiple sites)	0.004	0.996	0.000
T36 Poisoning by systemic antibiotics	0.004	0.996	0.000
R17 Unspecified jaundice	0.004	0.996	0.000
X23.9 Unspecified place	0.004	0.996	0.000
M25.54 Pain in joint (Hand)	0.004	0.996	0.000
T43.6 Psychostimulants with abuse potential	0.004	0.996	0.000
T43.9 Psychotropic drug, unspecified	0.003	0.996	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.003	0.996	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.003	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters	0.000	0.996	0.004
T43.5 Other and unspecified antipsychotics and neuroleptics	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
Z50.4 Psychotherapy, not elsewhere classified	0.000	0.997	0.003
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.997	0.000
T50.8 Diagnostic agents	0.003	0.997	0.000
T50.7 Analeptics and opioid receptor antagonists	0.003	0.997	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.003	0.997	0.000
T50.5 Appetite depressants	0.003	0.997	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.003	0.997	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.003	0.997	0.000
T50.1 Loop [high-ceiling] diuretics	0.003	0.997	0.000
T50.0 Mineralocorticoids and their antagonists	0.003	0.997	0.000
H35.8 Other specified retinal disorders	0.000	0.997	0.003
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.003	0.997	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.003	0.997	0.000
T47.7 Emetics	0.003	0.997	0.000
T47.6 Antidiarrhoeal drugs	0.003	0.997	0.000
T47.5 Digestants	0.003	0.997	0.000
T47.4 Other laxatives	0.003	0.997	0.000
T47.3 Saline and osmotic laxatives	0.003	0.997	0.000
T47.2 Stimulant laxatives	0.003	0.997	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.997	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.003	0.997	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.997	0.000
T37.5 Antiviral drugs	0.003	0.997	0.000
T37.4 Anthelminthics	0.003	0.997	0.000
T37.3 Other antiprotozoal drugs	0.003	0.997	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.997	0.000
T37.1 Antimycobacterial drugs	0.003	0.997	0.000
T37.0 Sulphonamides	0.003	0.997	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.997	0.003
T39.4 Antirheumatics, not elsewhere classified	0.003	0.997	0.000
T39.2 Pyrazolone derivatives	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.997	0.003
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.000	0.997	0.003
T41.5 Therapeutic gases	0.003	0.997	0.000
T41.4 Anaesthetic, unspecified	0.003	0.997	0.000
T41.3 Local anaesthetics	0.003	0.997	0.000
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T41.1 Intravenous anaesthetics	0.003	0.997	0.000
T41.0 Inhaled anaesthetics	0.003	0.997	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.003	0.997	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.997	0.000
T48.5 Anti-common-cold drugs	0.003	0.997	0.000
T48.4 Expectorants	0.003	0.997	0.000
T48.3 Antitussives	0.003	0.997	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.003	0.997	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.003	0.997	0.000
T48.0 Oxytocic drugs	0.003	0.997	0.000
T49.9 Topical agent, unspecified	0.003	0.997	0.000
T49.8 Other topical agents	0.003	0.997	0.000
T49.7 Dental drugs, topically applied	0.003	0.997	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.997	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.997	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.997	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.997	0.000
T49.2 Local astringents and local detergents	0.003	0.997	0.000
T49.1 Antipruritics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
M25.59 Pain in joint (Site unspecified)	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
S02.8 Fractures of other skull and facial bones	0.000	0.997	0.003
S02.2 Fracture of nasal bones	0.000	0.997	0.003
T36.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
T36.8 Other systemic antibiotics	0.003	0.997	0.000
T36.7 Antifungal antibiotics, systemically used	0.003	0.997	0.000
T36.6 Rifamycins	0.003	0.997	0.000
T36.5 Aminoglycosides	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
T36.3 Macrolides	0.003	0.997	0.000
T36.2 Chloramphenicol group	0.003	0.997	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.003	0.997	0.000
R10.3 Pain localised to other parts of lower abdomen	0.000	0.997	0.003
H52 Disorders of refraction and accommodation	0.000	0.997	0.003
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.000	0.997	0.003
T36.0 Penicillins	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
S06 Intracranial injury	0.000	0.997	0.003
M25.4 Effusion of joint	0.003	0.997	0.000
H52.2 Astigmatism	0.000	0.997	0.003
Z71.1 Person with feared complaint in whom no diagnosis is made	0.003	0.997	0.000
S72.10 Pertrochanteric fracture (closed)	0.000	0.997	0.002
I35.1 Aortic (valve) insufficiency	0.003	0.997	0.000
S02.3 Fracture of orbital floor	0.000	0.997	0.003
B97.7 Papillomavirus as the cause of diseases classified to other chapters	0.003	0.997	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.997	0.003
D05 Carcinoma in situ of breast	0.003	0.997	0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.000	0.997	0.003
M47.96 Spondylosis, unspecified (Lumbar region)	0.000	0.997	0.003
Z39.1 Care and examination of lactating mother	0.003	0.997	0.000
S02.0 Fracture of vault of skull	0.000	0.997	0.002
S06.3 Focal brain injury	0.000	0.997	0.002
H52.7 Disorder of refraction, unspecified	0.000	0.998	0.002
S02.5 Fracture of tooth	0.000	0.998	0.002
S02.21 Fracture of nasal bones (open)	0.000	0.998	0.002
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.002
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.002	0.998	0.000
H52.6 Other disorders of refraction	0.000	0.998	0.002
H52.5 Disorders of accommodation	0.000	0.998	0.002
H52.4 Presbyopia	0.000	0.998	0.002
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T45.5 Anticoagulants	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.002	0.998	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.002	0.998	0.000
T45.8 Other primarily systemic and haematological agents	0.002	0.998	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
T45.6 Fibrinolysis-affecting drugs	0.002	0.998	0.000
T45.4 Iron and its compounds	0.002	0.998	0.000
T45.3 Enzymes, not elsewhere classified	0.002	0.998	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
L90.5 Scar conditions and fibrosis of skin	0.000	0.998	0.002
S06.2 Diffuse brain injury	0.000	0.998	0.002
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.000	0.998	0.002
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.998	0.002
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
K76.0 Fatty (change of) liver, not elsewhere classified	0.002	0.998	0.000
X23 Contact with hornets, wasps and bees	0.002	0.998	0.000
T40.2 Other opioids	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
S06.7 Intracranial injury with prolonged coma	0.000	0.998	0.002
S06.4 Epidural haemorrhage	0.000	0.998	0.002
S06.1 Traumatic cerebral oedema	0.000	0.998	0.002
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
T45.2 Vitamins, not elsewhere classified	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
D05.0 Lobular carcinoma in situ	0.002	0.998	0.000
I35.0 Aortic (valve) stenosis	0.002	0.998	0.000
S02.6 Fracture of mandible	0.000	0.998	0.002
Q23.0 Congenital stenosis of aortic valve	0.002	0.998	0.000
S06.9 Intracranial injury, unspecified	0.000	0.998	0.002
S06.0 Concussion	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
Q44.6 Cystic disease of liver	0.002	0.998	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.000	0.998	0.002
B96 Other bacterial agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
S02.31 Fracture of orbital floor (open)	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.002	0.998	0.000
S02.50 Fracture of tooth (closed)	0.000	0.998	0.002
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.000	0.998	0.002
S09.8 Other specified injuries of head	0.000	0.998	0.002
I35 Nonrheumatic aortic valve disorders	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
J32.3 Chronic sphenoidal sinusitis	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.002
J32.2 Chronic ethmoidal sinusitis	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
S02.51 Fracture of tooth (open)	0.000	0.998	0.002
S06.31 Focal brain injury (with open intracranial wound)	0.000	0.998	0.002
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
I35.9 Aortic valve disorder, unspecified	0.002	0.998	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.998	0.002
S70-S79 Injuries to the hip and thigh	0.000	0.998	0.002
I35.8 Other aortic valve disorders	0.002	0.998	0.000
S09 Other and unspecified injuries of head	0.000	0.998	0.002
D05.7 Other carcinoma in situ of breast	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.998	0.002
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.002	0.998	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.002	0.998	0.000
Q23.4 Hypoplastic left heart syndrome	0.002	0.998	0.000
Q23.3 Congenital mitral insufficiency	0.002	0.998	0.000
Q23.2 Congenital mitral stenosis	0.002	0.998	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
C50.0 Nipple and areola	0.002	0.998	0.000
S09.9 Unspecified injury of head	0.000	0.998	0.002
X23.0 Home	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.000	0.998	0.002
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.998	0.002
C76.0 Head, face and neck	0.000	0.998	0.002
H34.1 Central retinal artery occlusion	0.000	0.998	0.002
X23.8 Other specified place	0.002	0.998	0.000
X23.7 Farm	0.002	0.998	0.000
X23.6 Industrial and construction area	0.002	0.998	0.000
X23.5 Trade and service area	0.002	0.998	0.000
X23.4 Street and highway	0.002	0.998	0.000
X23.3 Sports and athletics area	0.002	0.998	0.000
X23.2 School, other institution and public administrative area	0.002	0.998	0.000
X23.1 Residential institution	0.002	0.998	0.000
S06.8 Other intracranial injuries	0.000	0.998	0.002
J32 Chronic sinusitis	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.002
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.000	0.998	0.002
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.000	0.998	0.002
S06.41 Epidural haemorrhage (with open intracranial wound)	0.000	0.998	0.002
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.000	0.998	0.002
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
S02.61 Fracture of mandible (open)	0.000	0.998	0.002
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.998	0.002
S06.01 Concussion (with open intracranial wound)	0.000	0.998	0.002
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.000	0.998	0.002
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.000	0.998	0.002
H34 Retinal vascular occlusions	0.000	0.998	0.002
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.998	0.002
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.000	0.998	0.002
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters	0.000	0.998	0.002
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
C32.1 Supraglottis	0.000	0.998	0.002
H52.3 Anisometropia and aniseikonia	0.000	0.998	0.002
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
Q66.2 Metatarsus varus	0.002	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.998	0.002
Q65 Congenital deformities of hip	0.002	0.998	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.000	0.998	0.002
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters	0.000	0.998	0.002
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.998	0.002
C76.7 Other ill-defined sites	0.000	0.998	0.002
C76.5 Lower limb	0.000	0.998	0.002
C76.4 Upper limb	0.000	0.998	0.002
C76.3 Pelvis	0.000	0.998	0.002
C76.2 Abdomen	0.000	0.998	0.002
C80 Malignant neoplasm without specification of site	0.000	0.998	0.002
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.000	0.998	0.002
S77 Crushing injury of hip and thigh	0.000	0.998	0.002
S75 Injury of blood vessels at hip and thigh level	0.000	0.998	0.002
S74 Injury of nerves at hip and thigh level	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.001	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.002	0.998	0.000
M85.68 Other cyst of bone (Other)	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
S09.7 Multiple injuries of head	0.000	0.998	0.002
S09.2 Traumatic rupture of ear drum	0.000	0.998	0.002
S09.1 Injury of muscle and tendon of head	0.000	0.998	0.002
S09.0 Injury of blood vessels of head, not elsewhere classified	0.000	0.998	0.002
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
F31 Bipolar affective disorder	0.000	0.998	0.002
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
D05.9 Carcinoma in situ of breast, unspecified	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
Q74 Other congenital malformations of limb(s)	0.002	0.998	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.000	0.998	0.001
Q07.0 Arnold-Chiari syndrome	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.998	0.002
J32.1 Chronic frontal sinusitis	0.002	0.998	0.000
K60.5 Anorectal fistula	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
Q77.4 Achondroplasia	0.001	0.998	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
Q76 Congenital malformations of spine and bony thorax	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.000	0.998	0.001
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.001	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.001	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.001	0.998	0.000
T42.3 Barbiturates	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations