TreeWAS – Variant ID: rs11230201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H54.7 Unspecified visual loss	0.000	0.940	0.060
H54.0 Blindness, both eyes	0.000	0.959	0.041
H54 Blindness and low vision	0.000	0.961	0.039
H54.1 Blindness, one eye, low vision, other eye	0.000	0.967	0.033
H54.2 Low vision, both eyes	0.000	0.970	0.030
H54.3 Unqualified visual loss, both eyes	0.000	0.972	0.028
H54.5 Low vision, one eye	0.000	0.978	0.022
H54.6 Unqualified visual loss, one eye	0.000	0.981	0.019
H54.9 Unspecified visual impairment (binocular)	0.000	0.981	0.019
G30 Alzheimer's disease	0.000	0.981	0.019
G30.9 Alzheimer's disease, unspecified	0.000	0.982	0.018
G30.0 Alzheimer's disease with early onset	0.000	0.983	0.017
G30.8 Other Alzheimer's disease	0.000	0.983	0.017
E53.8 Deficiency of other specified B group vitamins	0.016	0.984	0.000
G30.1 Alzheimer's disease with late onset	0.000	0.985	0.015
N28.1 Cyst of kidney, acquired	0.000	0.986	0.014
G30-G32 Other degenerative diseases of the nervous system	0.000	0.987	0.013
N13.4 Hydroureter	0.000	0.988	0.012
N13.3 Other and unspecified hydronephrosis	0.000	0.988	0.012
N13 Obstructive and reflux uropathy	0.000	0.988	0.012
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.988	0.012
G31.0 Circumscribed brain atrophy	0.000	0.989	0.011
N13.8 Other obstructive and reflux uropathy	0.000	0.989	0.011
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.989	0.011
N13.7 Vesicoureteral-reflux-associated uropathy	0.000	0.990	0.010
K60.1 Chronic anal fissure	0.010	0.990	0.000
G31.2 Degeneration of nervous system due to alcohol	0.000	0.990	0.010
G31.8 Other specified degenerative diseases of nervous system	0.000	0.990	0.010
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.990	0.010
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.990	0.010
E53 Deficiency of other B group vitamins	0.010	0.990	0.000
G24.9 Dystonia, unspecified	0.009	0.990	0.000
G24 Dystonia	0.009	0.991	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.991	0.008
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.000	0.992	0.008
H54.4 Blindness, one eye	0.000	0.992	0.008
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.000	0.992	0.008
N99.0 Postprocedural renal failure	0.000	0.992	0.008
N99.5 Malfunction of external stoma of urinary tract	0.000	0.992	0.008
G24.8 Other dystonia	0.008	0.992	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.000	0.992	0.008
N99.1 Postprocedural urethral stricture	0.000	0.992	0.008
G24.3 Spasmodic torticollis	0.008	0.992	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.000	0.992	0.007
E53.9 Vitamin B deficiency, unspecified	0.007	0.992	0.000
R09.0 Asphyxia	0.000	0.993	0.007
M95.0 Acquired deformity of nose	0.007	0.993	0.000
G24.5 Blepharospasm	0.007	0.993	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.000	0.993	0.007
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.000	0.993	0.007
E53.1 Pyridoxine deficiency	0.007	0.993	0.000
E53.0 Riboflavin deficiency	0.007	0.993	0.000
I84.5 External haemorrhoids without complication	0.000	0.993	0.007
G24.1 Idiopathic familial dystonia	0.007	0.993	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.993	0.007
N13.6 Pyonephrosis	0.000	0.993	0.007
H53-H54 Visual disturbances and blindness	0.000	0.993	0.007
G24.0 Drug-induced dystonia	0.006	0.993	0.000
G24.4 Idiopathic orofacial dystonia	0.006	0.993	0.000
G24.2 Idiopathic nonfamilial dystonia	0.006	0.993	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.000	0.994	0.006
N99.8 Other postprocedural disorders of genito-urinary system	0.000	0.994	0.006
N99.2 Postprocedural adhesions of vagina	0.000	0.994	0.006
M95 Other acquired deformities of musculoskeletal system and connective tissue	0.005	0.995	0.000
R09.1 Pleurisy	0.000	0.995	0.005
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.000	0.995	0.005
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
C25.0 Head of pancreas	0.005	0.995	0.000
M96.0 Pseudarthrosis after fusion or arthrodesis	0.005	0.995	0.000
M95.3 Acquired deformity of neck	0.004	0.995	0.000
M95.2 Other acquired deformity of head	0.004	0.996	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.004	0.996	0.000
M95.9 Acquired deformity of musculoskeletal system, unspecified	0.004	0.996	0.000
M95.8 Other specified acquired deformities of musculoskeletal system	0.004	0.996	0.000
M95.5 Acquired deformity of pelvis	0.004	0.996	0.000
M95.1 Cauliflower ear	0.004	0.996	0.000
R53 Malaise and fatigue	0.000	0.996	0.004
Q18.0 Sinus, fistula and cyst of branchial cleft	0.000	0.996	0.004
S22.20 Fracture of sternum (closed)	0.004	0.996	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.996	0.004
M95.4 Acquired deformity of chest and rib	0.004	0.996	0.000
E14.3 With ophthalmic complications	0.000	0.996	0.004
C25.9 Pancreas, unspecified	0.004	0.996	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.004	0.996	0.000
N99.3 Prolapse of vaginal vault after hysterectomy	0.000	0.996	0.004
M96.1 Postlaminectomy syndrome, not elsewhere classified	0.004	0.996	0.000
E50-E64 Other nutritional deficiencies	0.004	0.996	0.000
R09.3 Abnormal sputum	0.000	0.996	0.004
D11.0 Parotid gland	0.000	0.996	0.004
T88 Other complications of surgical and medical care, not elsewhere classified	0.004	0.996	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.004	0.996	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.004	0.996	0.000
M96.5 Postradiation scoliosis	0.003	0.996	0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.000	0.996	0.004
T88.4 Failed or difficult intubation	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
N99-N99 Other disorders of the genitourinary system	0.000	0.996	0.004
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.003	0.997	0.000
M96.6 Fracture of bone following insertion of orthopaedic implant, joint prosthesis or bone plate	0.003	0.997	0.000
M96.4 Postsurgical lordosis	0.003	0.997	0.000
M96.3 Postlaminectomy kyphosis	0.003	0.997	0.000
M96.2 Postradiation kyphosis	0.003	0.997	0.000
N64.8 Other specified disorders of breast	0.003	0.997	0.000
R09.2 Respiratory arrest	0.000	0.997	0.003
M95.96 Acquired deformity of musculoskeletal system, unspecified	0.003	0.997	0.000
T88.2 Shock due to anaesthesia	0.003	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.003	0.997	0.000
S82.00 Fracture of patella (closed)	0.003	0.997	0.000
E55 Vitamin D deficiency	0.003	0.997	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.003	0.997	0.000
N88.2 Stricture and stenosis of cervix uteri	0.003	0.997	0.000
T88.5 Other complications of anaesthesia	0.003	0.997	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.003	0.997	0.000
E61 Deficiency of other nutrient elements	0.003	0.997	0.000
M96.9 Postprocedural musculoskeletal disorder, unspecified	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.997	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.003	0.997	0.000
E64 Sequelae of malnutrition and other nutritional deficiencies	0.003	0.997	0.000
E50 Vitamin A deficiency	0.003	0.997	0.000
E60 Dietary zinc deficiency	0.003	0.997	0.000
E59 Dietary selenium deficiency	0.003	0.997	0.000
E52 Niacin deficiency [pellagra]	0.003	0.997	0.000
E63 Other nutritional deficiencies	0.003	0.997	0.000
J18.0 Bronchopneumonia, unspecified	0.003	0.997	0.000
T88.9 Complication of surgical and medical care, unspecified	0.003	0.997	0.000
N39.9 Disorder of urinary system, unspecified	0.000	0.997	0.003
T88.3 Malignant hyperthermia due to anaesthesis	0.003	0.997	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.003	0.997	0.000
T88.0 Infection following immunisation	0.003	0.997	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.997	0.003
C25.7 Other parts of pancreas	0.003	0.997	0.000
E61.2 Magnesium deficiency	0.003	0.997	0.000
E58 Dietary calcium deficiency	0.003	0.997	0.000
S12.2 Fracture of other specified cervical vertebra	0.000	0.997	0.003
E51 Thiamine deficiency	0.003	0.997	0.000
C67.9 Bladder, unspecified	0.000	0.997	0.003
S82.8 Fractures of other parts of lower leg	0.003	0.997	0.000
E54 Ascorbic acid deficiency	0.003	0.997	0.000
M99 Biomechanical lesions, not elsewhere classified	0.003	0.997	0.000
C25.2 Tail of pancreas	0.003	0.997	0.000
E56 Other vitamin deficiencies	0.003	0.997	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.997	0.003
E55.9 Vitamin D deficiency, unspecified	0.003	0.997	0.000
M96.65 Fracture of pelvis following insertion of orthopedic implant, joint prosthesis, or bone plate (Fx pelvis following insrt ortho implnt/prosth/bone plt)	0.002	0.997	0.000
M96.63 Fracture of radius or ulna following insertion of orthopedic implant, joint prosthesis, or bone plate	0.002	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.000	0.997	0.003
G12.2 Motor neuron disease	0.000	0.997	0.003
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified	0.000	0.997	0.003
C25.3 Pancreatic duct	0.003	0.997	0.000
C25.1 Body of pancreas	0.003	0.997	0.000
R23.1 Pallor	0.000	0.997	0.003
M25.54 Pain in joint (Hand)	0.003	0.997	0.000
E55.0 Rickets, active	0.002	0.997	0.000
S82.0 Fracture of patella	0.003	0.997	0.000
M31.3 Wegener's granulomatosis	0.003	0.997	0.000
H02.4 Ptosis of eyelid	0.003	0.997	0.000
S82.81 Fractures of other parts of lower leg (open)	0.002	0.998	0.000
E61.9 Deficiency of nutrient element, unspecified	0.002	0.998	0.000
E61.8 Deficiency of other specified nutrient elements	0.002	0.998	0.000
E61.7 Deficiency of multiple nutrient elements	0.002	0.998	0.000
E61.6 Vanadium deficiency	0.002	0.998	0.000
E61.5 Molybdenum deficiency	0.002	0.998	0.000
E61.4 Chromium deficiency	0.002	0.998	0.000
E61.3 Manganese deficiency	0.002	0.998	0.000
E61.0 Copper deficiency	0.002	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.002	0.998	0.000
G71.1 Myotonic disorders	0.000	0.998	0.002
E50.9 Vitamin A deficiency, unspecified	0.002	0.998	0.000
E50.8 Other manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.7 Other ocular manifestations of vitamin A deficiency	0.002	0.998	0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.002	0.998	0.000
E50.5 Vitamin A deficiency with night blindness	0.002	0.998	0.000
E50.4 Vitamin A deficiency with keratomalacia	0.002	0.998	0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.002	0.998	0.000
E50.2 Vitamin A deficiency with corneal xerosis	0.002	0.998	0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.002	0.998	0.000
E50.0 Vitamin A deficiency with conjunctival xerosis	0.002	0.998	0.000
E63.8 Other specified nutritional deficiencies	0.002	0.998	0.000
E63.1 Imbalance of constituents of food intake	0.002	0.998	0.000
E63.0 Essential fatty acid [EFA] deficiency	0.002	0.998	0.000
E64.9 Sequelae of unspecified nutritional deficiency	0.002	0.998	0.000
E64.8 Sequelae of other nutritional deficiencies	0.002	0.998	0.000
E64.3 Sequelae of rickets	0.002	0.998	0.000
E64.2 Sequelae of vitamin C deficiency	0.002	0.998	0.000
E64.1 Sequelae of vitamin A deficiency	0.002	0.998	0.000
E64.0 Sequelae of protein-energy malnutrition	0.002	0.998	0.000
Q18 Other congenital malformations of face and neck	0.000	0.998	0.002
E63.9 Nutritional deficiency, unspecified	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
N10 Acute tubulo-interstitial nephritis	0.000	0.998	0.002
N10-N16 Renal tubulo-interstitial diseases	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.002	0.998	0.000
N05.9 Unspecified	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.998	0.002
E51.9 Thiamine deficiency, unspecified	0.002	0.998	0.000
E51.8 Other manifestations of thiamine deficiency	0.002	0.998	0.000
E51.1 Beriberi	0.002	0.998	0.000
S82.86 Maisonneuve's fracture	0.002	0.998	0.000
B02.2 Zoster with other nervous system involvement	0.002	0.998	0.000
H11.3 Conjunctival haemorrhage	0.002	0.998	0.000
M99.9 Biomechanical lesion, unspecified	0.002	0.998	0.000
M99.7 Connective tissue and disk stenosis of intervertebral foramina	0.002	0.998	0.000
M99.6 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.4 Connective tissue stenosis of neural canal	0.002	0.998	0.000
M99.3 Osseous stenosis of neural canal	0.002	0.998	0.000
M99.2 Subluxation stenosis of neural canal	0.002	0.998	0.000
M99.1 Subluxation complex (vertebral)	0.002	0.998	0.000
M99.0 Segmental and somatic dysfunction	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
H11 Other disorders of conjunctiva	0.002	0.998	0.000
E56.9 Vitamin deficiency, unspecified	0.002	0.998	0.000
E56.8 Deficiency of other vitamins	0.002	0.998	0.000
E56.0 Deficiency of vitamin E	0.002	0.998	0.000
H11.1 Conjunctival degenerations and deposits	0.002	0.998	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.002	0.998	0.000
M50.1 Cervical disk disorder with radiculopathy	0.002	0.998	0.000
G25.0 Essential tremor	0.002	0.998	0.000
M99.8 Other biomechanical lesions	0.002	0.998	0.000
Q66 Congenital deformities of feet	0.002	0.998	0.000
Q65 Congenital deformities of hip	0.002	0.998	0.000
G20-G26 Extrapyramidal and movement disorders	0.002	0.998	0.000
S82.01 Fracture of patella (open)	0.002	0.998	0.000
E51.2 Wernicke's encephalopathy	0.002	0.998	0.000
S82.5 Fracture of medial malleolus	0.002	0.998	0.000
Z32.1 Pregnancy confirmed	0.000	0.998	0.002
Z43.6 Attention to other artificial openings of urinary tract	0.000	0.998	0.002
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
Q65.8 Other congenital deformities of hip	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
N75.1 Abscess of Bartholin's gland	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
D47.3 Essential (haemorrhagic) thrombocythaemia	0.000	0.998	0.002
Z40.8 Other prophylactic surgery	0.000	0.998	0.002
Q65.2 Congenital dislocation of hip, unspecified	0.002	0.998	0.000
G23 Other degenerative diseases of basal ganglia	0.002	0.998	0.000
M31 Other necrotising vasculopathies	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.000	0.998	0.002
E61.1 Iron deficiency	0.002	0.998	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.002	0.998	0.000
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
Q66.0 Talipes equinovarus	0.002	0.998	0.000
U88 Agent resistant to multiple antibiotics	0.000	0.998	0.002
D35.0 Adrenal gland	0.000	0.998	0.002
Q18.9 Congenital malformation of face and neck, unspecified	0.000	0.998	0.002
Q18.8 Other specified congenital malformations of face and neck	0.000	0.998	0.002
Q18.7 Microcheilia	0.000	0.998	0.002
Q18.6 Macrocheilia	0.000	0.998	0.002
Q18.5 Microstomia	0.000	0.998	0.002
Q18.4 Macrostomia	0.000	0.998	0.002
Q18.3 Webbing of neck	0.000	0.998	0.002
Q18.2 Other branchial cleft malformations	0.000	0.998	0.002
Q66.7 Pes cavus	0.002	0.998	0.000
Q66.2 Metatarsus varus	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.998	0.002
M99.5 Intervertebral disk stenosis of neural canal	0.002	0.998	0.000
Q67.5 Congenital deformity of spine	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.000	0.998	0.002
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.002	0.998	0.000
Q65.1 Congenital dislocation of hip, bilateral	0.002	0.998	0.000
D11 Benign neoplasm of major salivary glands	0.000	0.998	0.002
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.000	0.998	0.002
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.002	0.998	0.000
S82 Fracture of lower leg, including ankle	0.002	0.998	0.000
M99.09 Segmental and somatic dysfunction (Abdomen and other)	0.002	0.998	0.000
M99.08 Segmental and somatic dysfunction (Rib cage)	0.002	0.998	0.000
M99.07 Segmental and somatic dysfunction (Upper extremity)	0.002	0.998	0.000
M99.06 Segmental and somatic dysfunction (Lower extremity)	0.002	0.998	0.000
M99.05 Segmental and somatic dysfunction (Pelvic region)	0.002	0.998	0.000
M99.04 Segmental and somatic dysfunction (Sacral region)	0.002	0.998	0.000
M99.03 Segmental and somatic dysfunction (Lumbar region)	0.002	0.998	0.000
M99.02 Segmental and somatic dysfunction (Thoracic region)	0.002	0.998	0.000
M99.01 Segmental and somatic dysfunction (Cervical region)	0.002	0.998	0.000
M99.00 Segmental and somatic dysfunction (Head region)	0.002	0.998	0.000
M99.19 Subluxation complex (vertebral) (Abdomen and other)	0.002	0.998	0.000
M99.18 Subluxation complex (vertebral) (Rib cage)	0.002	0.998	0.000
M99.17 Subluxation complex (vertebral) (Upper extremity)	0.002	0.998	0.000
M99.16 Subluxation complex (vertebral) (Lower extremity)	0.002	0.998	0.000
M99.15 Subluxation complex (vertebral) (Pelvic region)	0.002	0.998	0.000
M99.14 Subluxation complex (vertebral) (Sacral region)	0.002	0.998	0.000
M99.13 Subluxation complex (vertebral) (Lumbar region)	0.002	0.998	0.000
M99.12 Subluxation complex (vertebral) (Thoracic region)	0.002	0.998	0.000
M99.11 Subluxation complex (vertebral) (Cervical region)	0.002	0.998	0.000
M99.10 Subluxation complex (vertebral) (Head region)	0.002	0.998	0.000
M99.29 Subluxation stenosis of neural canal-Abdomen/other	0.002	0.998	0.000
M99.28 Subluxation stenosis of neural canal-Rib cage	0.002	0.998	0.000
M99.27 Subluxation stenosis of neural canal-Upper extremity	0.002	0.998	0.000
M99.26 Subluxation stenosis of neural canal-Lower extremity	0.002	0.998	0.000
M99.25 Subluxation stenosis of neural canal (Pelvic region)	0.002	0.998	0.000
M99.24 Subluxation stenosis of neural canal (Sacral region)	0.002	0.998	0.000
M99.23 Subluxation stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
M99.22 Subluxation stenosis of neural canal (Thoracic region)	0.002	0.998	0.000
M99.21 Subluxation stenosis of neural canal (Cervical region)	0.002	0.998	0.000
M99.20 Subluxation stenosis of neural canal (Head region)	0.002	0.998	0.000
M99.39 Osseous stenosis of neural canal-Abdomen/other	0.002	0.998	0.000
M99.38 Osseous stenosis of neural canal-Rib cage	0.002	0.998	0.000
M99.37 Osseous stenosis of neural canal-Upper extremity	0.002	0.998	0.000
M99.36 Osseous stenosis of neural canal-Lower extremity	0.002	0.998	0.000
M99.35 Osseous stenosis of neural canal (Pelvic region)	0.002	0.998	0.000
M99.34 Osseous stenosis of neural canal (Sacral region)	0.002	0.998	0.000
M99.33 Osseous stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
M99.32 Osseous stenosis of neural canal (Thoracic region)	0.002	0.998	0.000
M99.31 Osseous stenosis of neural canal (Cervical region)	0.002	0.998	0.000
M99.30 Osseous stenosis of neural canal (Head region)	0.002	0.998	0.000
M99.49 Connective tissue stenosis of neural canal-Abdomen/other	0.002	0.998	0.000
M99.48 Connective tissue stenosis of neural canal-Rib cage	0.002	0.998	0.000
M99.47 Connective tissue stenosis of neural canal-Upper extremity	0.002	0.998	0.000
M99.46 Connective tissue stenosis of neural canal-Lower extremity	0.002	0.998	0.000
M99.45 Connective tissue stenosis of neural canal (Pelvic region)	0.002	0.998	0.000
M99.44 Connective tissue stenosis of neural canal (Sacral region)	0.002	0.998	0.000
M99.43 Connective tissue stenosis of neural canal (Lumbar region)	0.002	0.998	0.000
M99.42 Connective tissue stenosis of neural canal (Thoracic region)	0.002	0.998	0.000
M99.41 Connective tissue stenosis of neural canal (Cervical region)	0.002	0.998	0.000
M99.40 Connective tissue stenosis of neural canal (Head region)	0.002	0.998	0.000
M99.69 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.68 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.67 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.66 Osseous and subluxation stenosis of intervertebral foramina	0.002	0.998	0.000
M99.65 Osseous and subluxation stenosis of intervertebral foramina (Pelvic region)	0.002	0.998	0.000
M99.64 Osseous and subluxation stenosis of intervertebral foramina (Sacral region)	0.002	0.998	0.000
M99.63 Osseous and subluxation stenosis of intervertebral foramina (Lumbar region)	0.002	0.998	0.000
M99.62 Osseous and subluxation stenosis of intervertebral foramina (Thoracic region)	0.002	0.998	0.000
M99.61 Osseous and subluxation stenosis of intervertebral foramina (Cervical region)	0.002	0.998	0.000
M99.60 Osseous and subluxation stenosis of intervertebral foramina (Head region)	0.002	0.998	0.000
M99.79 Connective tis and disc stenosis of intervertebral foramina	0.002	0.998	0.000
M99.78 Connective tis and disc stenosis of intervertebral foramina	0.002	0.998	0.000
M99.77 Connective tis and disc stenosis of intervertebral foramina	0.002	0.998	0.000
M99.76 Connective tis and disc stenosis of intervertebral foramina	0.002	0.998	0.000
M99.75 Connective tissue and disc stenosis of intervertebral foramina (Pelvic region)	0.002	0.998	0.000
M99.74 Connective tissue and disc stenosis of intervertebral foramina (Sacral region)	0.002	0.998	0.000
M99.73 Connective tissue and disc stenosis of intervertebral foramina (Lumbar region)	0.002	0.998	0.000
M99.72 Connective tissue and disc stenosis of intervertebral foramina (Thoracic region)	0.002	0.998	0.000
M99.71 Connective tissue and disc stenosis of intervertebral foramina (Cervical region)	0.002	0.998	0.000
M99.70 Connective tissue and disc stenosis of intervertebral foramina (Head region)	0.002	0.998	0.000
M99.99 Biomechanical lesion, unspecified (Abdomen and other)	0.002	0.998	0.000
M99.98 Biomechanical lesion, unspecified (Rib cage)	0.002	0.998	0.000
M99.97 Biomechanical lesion, unspecified (Upper extremity)	0.002	0.998	0.000
M99.96 Biomechanical lesion, unspecified (Lower extremity)	0.002	0.998	0.000
M99.95 Biomechanical lesion, unspecified (Pelvic region)	0.002	0.998	0.000
M99.94 Biomechanical lesion, unspecified (Sacral region)	0.002	0.998	0.000
M99.93 Biomechanical lesion, unspecified (Lumbar region)	0.002	0.998	0.000
M99.92 Biomechanical lesion, unspecified (Thoracic region)	0.002	0.998	0.000
M99.91 Biomechanical lesion, unspecified (Cervical region)	0.002	0.998	0.000
M99.90 Biomechanical lesion, unspecified (Head region)	0.002	0.998	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
N92.6 Irregular menstruation, unspecified	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.000	0.998	0.002
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.002	0.998	0.000
S22.2 Fracture of sternum	0.002	0.998	0.000
N15 Other renal tubulo-interstitial diseases	0.000	0.998	0.002
M99.89 Other biomechanical lesions (Abdomen and other)	0.002	0.998	0.000
M99.88 Other biomechanical lesions (Rib cage)	0.002	0.998	0.000
M99.87 Other biomechanical lesions (Upper extremity)	0.002	0.998	0.000
M99.86 Other biomechanical lesions (Lower extremity)	0.002	0.998	0.000
M99.85 Other biomechanical lesions (Pelvic region)	0.002	0.998	0.000
M99.84 Other biomechanical lesions (Sacral region)	0.002	0.998	0.000
M99.82 Other biomechanical lesions (Thoracic region)	0.002	0.998	0.000
M99.80 Other biomechanical lesions (Head region)	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.000	0.998	0.002
Q66.9 Congenital deformity of feet, unspecified	0.002	0.998	0.000
Q66.3 Other congenital varus deformities of feet	0.002	0.998	0.000
M99.81 Other biomechanical lesions (Cervical region)	0.002	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.002
Q18.1 Preauricular sinus and cyst	0.000	0.998	0.002
G71 Primary disorders of muscles	0.000	0.998	0.002
M31.7 Microscopic polyangiitis	0.002	0.998	0.000
N05.2 Diffuse membranous glomerulonephritis	0.002	0.998	0.000
Q65.9 Congenital deformity of hip, unspecified	0.002	0.998	0.000
Q65.6 Unstable hip	0.002	0.998	0.000
Q65.5 Congenital subluxation of hip, unspecified	0.002	0.998	0.000
Q65.4 Congenital subluxation of hip, bilateral	0.002	0.998	0.000
Q65.3 Congenital subluxation of hip, unilateral	0.002	0.998	0.000
Q65.0 Congenital dislocation of hip, unilateral	0.002	0.998	0.000
Q66.5 Congenital pes planus	0.002	0.998	0.000
Q66.4 Talipes calcaneovalgus	0.002	0.998	0.000
Q66.1 Talipes calcaneovarus	0.002	0.998	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.002	0.998	0.000
G22 Parkinsonism in diseases classified elsewhere	0.002	0.998	0.000
M99.83 Other biomechanical lesions (Lumbar region)	0.002	0.998	0.000
R23 Other skin changes	0.000	0.998	0.002
S82.9 Fracture of lower leg, part unspecified	0.002	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.000	0.998	0.002
D11.7 Other major salivary glands	0.000	0.998	0.002
Q66.8 Other congenital deformities of feet	0.002	0.998	0.000
Q66.6 Other congenital valgus deformities of feet	0.002	0.998	0.000
Q67.6 Pectus excavatum	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
H11.2 Conjunctival scars	0.002	0.998	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.000	0.998	0.002
G21 Secondary Parkinsonism	0.002	0.998	0.000
N11 Chronic tubulo-interstitial nephritis	0.000	0.998	0.002
Q68 Other congenital musculoskeletal deformities	0.002	0.998	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.002	0.998	0.000
G23.3 Multiple system atrophy, cerebellar type	0.002	0.998	0.000
G23.2 Striatonigral degeneration	0.002	0.998	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.002	0.998	0.000
G23.0 Hallervorden-Spatz disease	0.002	0.998	0.000
M31.2 Lethal midline granuloma	0.002	0.998	0.000
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
Q67.8 Other congenital deformities of chest	0.002	0.998	0.000
Q67.7 Pectus carinatum	0.002	0.998	0.000
Q67.3 Plagiocephaly	0.002	0.998	0.000
Q67.2 Dolichocephaly	0.002	0.998	0.000
Q67.1 Compression facies	0.002	0.998	0.000
Q67.0 Facial asymmetry	0.002	0.998	0.000
Q79.1 Other congenital malformations of diaphragm	0.002	0.998	0.000
N05 Unspecified nephritic syndrome	0.002	0.998	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.998	0.000
G25.5 Other chorea	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.000	0.998	0.002
D11.9 Major salivary gland, unspecified	0.000	0.998	0.002
G93.8 Other specified disorders of brain	0.000	0.998	0.002
K70.4 Alcoholic hepatic failure	0.002	0.998	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.998	0.002
H10 Conjunctivitis	0.002	0.998	0.000
Q78 Other osteochondrodysplasias	0.002	0.998	0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other	0.001	0.998	0.000
M99.58 Intervertebral disc stenosis of neural canal-Rib cage	0.001	0.998	0.000
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit	0.001	0.998	0.000
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit	0.001	0.998	0.000
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)	0.001	0.998	0.000
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)	0.001	0.998	0.000
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)	0.001	0.998	0.000
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)	0.001	0.998	0.000
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.998	0.002
U84 Resistance to other antimicrobial drugs	0.000	0.998	0.002
U83 Resistance to other antibiotics	0.000	0.998	0.002
U82 Resistance to betalactam antibiotics	0.000	0.998	0.002
U85 Resistance to antineoplastic drugs	0.000	0.998	0.002
C67.2 Lateral wall of bladder	0.000	0.998	0.002
H11.8 Other specified disorders of conjunctiva	0.002	0.998	0.000
N05.1 Focal and segmental glomerular lesions	0.002	0.998	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.002	0.998	0.000
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
Z40 Prophylactic surgery	0.000	0.998	0.002
M21.76 Unequal limb length (acquired) (Lower leg)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
N14.4 Toxic nephropathy, not elsewhere classified	0.000	0.998	0.001
N14.3 Nephropathy induced by heavy metals	0.000	0.998	0.001
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.000	0.998	0.001
N14.0 Analgesic nephropathy	0.000	0.998	0.001
R23.2 Flushing	0.000	0.998	0.002
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.000	0.998	0.002
E22.1 Hyperprolactinaemia	0.000	0.998	0.002
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.000	0.998	0.002
G12 Spinal muscular atrophy and related syndromes	0.000	0.998	0.002
Q75 Other congenital malformations of skull and face bones	0.002	0.998	0.000
Q73 Reduction defects of unspecified limb	0.002	0.998	0.000
Q72 Reduction defects of lower limb	0.002	0.998	0.000
Q71 Reduction defects of upper limb	0.002	0.998	0.000
Q70 Syndactyly	0.002	0.998	0.000
Q69 Polydactyly	0.002	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.998	0.002
S22.21 Fracture of sternum (open)	0.001	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
M31.6 Other giant cell arteritis	0.002	0.998	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.000	0.998	0.001
N15.0 Balkan nephropathy	0.000	0.998	0.001
R57.0 Cardiogenic shock	0.000	0.998	0.002
Z35.1 Supervision of pregnancy with history of abortive outcome	0.002	0.998	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.998	0.001
G71.8 Other primary disorders of muscles	0.000	0.998	0.001
G71.2 Congenital myopathies	0.000	0.998	0.001
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.002	0.998	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.001	0.998	0.000
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.001	0.998	0.000
H11.9 Disorder of conjunctiva, unspecified	0.002	0.998	0.000
N48.4 Impotence of organic origin	0.002	0.998	0.000
R23.4 Changes in skin texture	0.000	0.998	0.002
S82.91 Fracture of lower leg, part unspecified (open)	0.001	0.998	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.001	0.998	0.000
G25.4 Drug-induced chorea	0.001	0.998	0.000
G25.1 Drug-induced tremor	0.001	0.998	0.000
N05.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.998	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.000	0.998	0.001
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.000	0.998	0.001
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.000	0.998	0.001
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.000	0.998	0.001
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.000	0.998	0.001
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.000	0.998	0.001
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.000	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations