TreeWAS – Variant ID: rs11259474

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N13.5 Kinking and stricture of ureter without hydronephrosis	0.032	0.968	0.000
C15.5 Lower third of oesophagus	0.000	0.979	0.021
C15.9 Oesophagus, unspecified	0.000	0.980	0.020
C15 Malignant neoplasm of oesophagus	0.000	0.980	0.020
C15.4 Middle third of oesophagus	0.000	0.984	0.016
C15.3 Upper third of oesophagus	0.000	0.985	0.015
N13 Obstructive and reflux uropathy	0.014	0.986	0.000
C15.8 Overlapping lesion of oesophagus	0.000	0.986	0.014
C15.2 Abdominal part of oesophagus	0.000	0.986	0.014
C15.1 Thoracic part of oesophagus	0.000	0.986	0.014
C15.0 Cervical part of oesophagus	0.000	0.986	0.014
N13.3 Other and unspecified hydronephrosis	0.012	0.988	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.012	0.988	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.011	0.989	0.000
N13.4 Hydroureter	0.011	0.989	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.011	0.989	0.000
T40.4 Other synthetic narcotics	0.010	0.990	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.010	0.990	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.009	0.991	0.000
N13.6 Pyonephrosis	0.008	0.991	0.000
C67 Malignant neoplasm of bladder	0.009	0.991	0.000
C67.9 Bladder, unspecified	0.009	0.991	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
C67.0 Trigone of bladder	0.008	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.008	0.992	0.000
C67.2 Lateral wall of bladder	0.008	0.992	0.000
C67.8 Overlapping lesion of bladder	0.008	0.992	0.000
C67.6 Ureteric orifice	0.008	0.992	0.000
T40.2 Other opioids	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.007	0.993	0.000
C67.1 Dome of bladder	0.007	0.993	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.007	0.993	0.000
T40.8 Lysergide [LSD]	0.007	0.993	0.000
T40.7 Cannabis (derivatives)	0.007	0.993	0.000
T40.5 Cocaine	0.007	0.993	0.000
T40.3 Methadone	0.007	0.993	0.000
T40.1 Heroin	0.007	0.993	0.000
T40.0 Opium	0.007	0.993	0.000
T40.6 Other and unspecified narcotics	0.007	0.993	0.000
N10-N16 Renal tubulo-interstitial diseases	0.007	0.993	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.007	0.993	0.000
T46.1 Calcium-channel blockers	0.007	0.993	0.000
N13.8 Other obstructive and reflux uropathy	0.006	0.993	0.000
T42.1 Iminostilbenes	0.007	0.993	0.000
T43.6 Psychostimulants with abuse potential	0.006	0.994	0.000
C67.7 Urachus	0.006	0.994	0.000
T43.2 Other and unspecified antidepressants	0.006	0.994	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.006	0.994	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
N11 Chronic tubulo-interstitial nephritis	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
C67.5 Bladder neck	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
T46.7 Peripheral vasodilators	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
N15 Other renal tubulo-interstitial diseases	0.006	0.994	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.006	0.994	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.006	0.994	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.006	0.994	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
T42.0 Hydantoin derivatives	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
C67.3 Anterior wall of bladder	0.006	0.994	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
T36.0 Penicillins	0.006	0.994	0.000
T45.2 Vitamins, not elsewhere classified	0.006	0.994	0.000
N11.1 Chronic obstructive pyelonephritis	0.006	0.994	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.994	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.994	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.994	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.005	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.005	0.994	0.000
T42.3 Barbiturates	0.005	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.005	0.994	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
N15.9 Renal tubulo-interstitial disease, unspecified	0.005	0.995	0.000
X62.9 Unspecified place	0.005	0.995	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.005	0.995	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.005	0.995	0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T36.3 Macrolides	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.005	0.995	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.005	0.995	0.000
T37.5 Antiviral drugs	0.005	0.995	0.000
T37.4 Anthelminthics	0.005	0.995	0.000
T37.3 Other antiprotozoal drugs	0.005	0.995	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.005	0.995	0.000
T37.1 Antimycobacterial drugs	0.005	0.995	0.000
T37.0 Sulphonamides	0.005	0.995	0.000
C67.4 Posterior wall of bladder	0.005	0.995	0.000
N10 Acute tubulo-interstitial nephritis	0.005	0.995	0.000
N15.1 Renal and perinephric abscess	0.005	0.995	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.005	0.995	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.005	0.995	0.000
T38.9 Other and unspecified hormone antagonists	0.005	0.995	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.005	0.995	0.000
T38.7 Androgens and anabolic congeners	0.005	0.995	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.005	0.995	0.000
T38.5 Other oestrogens and progestogens	0.005	0.995	0.000
T38.4 Oral contraceptives	0.005	0.995	0.000
T38.2 Antithyroid drugs	0.005	0.995	0.000
T38.1 Thyroid hormones and substitutes	0.005	0.995	0.000
T38.0 Glucocorticoids and synthetic analogues	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
N11.8 Other chronic tubulo-interstitial nephritis	0.005	0.995	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.005	0.995	0.000
N15.8 Other specified renal tubulo-interstitial diseases	0.004	0.995	0.000
N15.0 Balkan nephropathy	0.004	0.995	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.995	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.995	0.000
T47.7 Emetics	0.004	0.995	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.995	0.000
T47.5 Digestants	0.004	0.995	0.000
T47.4 Other laxatives	0.004	0.995	0.000
T47.3 Saline and osmotic laxatives	0.004	0.995	0.000
T47.2 Stimulant laxatives	0.004	0.995	0.000
T47.0 Histamine H(2)-receptor antagonists	0.004	0.995	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.004	0.995	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.004	0.995	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.995	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.004	0.995	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.004	0.995	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.004	0.995	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.004	0.995	0.000
T44.0 Anticholinesterase agents	0.004	0.995	0.000
T50.8 Diagnostic agents	0.004	0.995	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.995	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.995	0.000
T50.5 Appetite depressants	0.004	0.995	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.995	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.995	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.995	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.995	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.995	0.000
S42.00 Fracture of clavicle (closed)	0.004	0.996	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.004	0.996	0.000
C44.1 Skin of eyelid, including canthus	0.000	0.996	0.004
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
S22.30 Fracture of rib (closed)	0.004	0.996	0.000
O82.0 Delivery by elective Caesarean section	0.004	0.996	0.000
G63.2 Diabetic polyneuropathy	0.000	0.996	0.004
T45.0 Antiallergic and antiemetic drugs	0.004	0.996	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.004	0.996	0.000
N14.3 Nephropathy induced by heavy metals	0.004	0.996	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.004	0.996	0.000
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.004	0.996	0.000
N14.0 Analgesic nephropathy	0.004	0.996	0.000
N16.8 Renal tubulo-interstitial disorders in other diseases classified elsewhere	0.004	0.996	0.000
N16.5 Renal tubulo-interstitial disorders in transplant rejection	0.004	0.996	0.000
N16.4 Renal tubulo-interstitial disorders in systemic connective tissue disorders	0.004	0.996	0.000
N16.3 Renal tubulo-interstitial disorders in metabolic diseases	0.004	0.996	0.000
N16.2 Renal tubulo-interstitial disorders in blood diseases and disorders involving the immune mechanism	0.004	0.996	0.000
N16.1 Renal tubulo-interstitial disorders in neoplastic diseases	0.004	0.996	0.000
N16.0 Renal tubulo-interstitial disorders in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.996	0.000
R49.0 Dysphonia	0.004	0.996	0.000
L60.2 Onychogryphosis	0.003	0.996	0.000
L60.0 Ingrowing nail	0.003	0.997	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.003	0.997	0.000
L60 Nail disorders	0.003	0.997	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.003	0.997	0.000
F05.9 Delirium, unspecified	0.003	0.997	0.000
K85.1 Biliary acute pancreatitis	0.003	0.997	0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters	0.003	0.997	0.000
L60.3 Nail dystrophy	0.003	0.997	0.000
R47.8 Other and unspecified speech disturbances	0.003	0.997	0.000
B37.8 Candidiasis of other sites	0.003	0.997	0.000
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.997	0.003
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
O82 Single delivery by Caesarean section	0.003	0.997	0.000
L60.9 Nail disorder, unspecified	0.003	0.997	0.000
C71.1 Frontal lobe	0.000	0.997	0.003
L60.5 Yellow nail syndrome	0.002	0.997	0.000
L60.4 Beau's lines	0.002	0.997	0.000
L60.1 Onycholysis	0.002	0.997	0.000
S42.0 Fracture of clavicle	0.002	0.998	0.000
S22.3 Fracture of rib	0.002	0.998	0.000
X62.0 Home	0.002	0.998	0.000
X62.8 Other specified place	0.002	0.998	0.000
X62.7 Farm	0.002	0.998	0.000
X62.6 Industrial and construction area	0.002	0.998	0.000
X62.5 Trade and service area	0.002	0.998	0.000
X62.4 Street and highway	0.002	0.998	0.000
X62.3 Sports and athletics area	0.002	0.998	0.000
X62.2 School, other institution and public administrative area	0.002	0.998	0.000
X62.1 Residential institution	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
R19.5 Other fecal abnormalities	0.002	0.998	0.000
Z33 Pregnant state, incidental	0.002	0.998	0.000
T42.4 Benzodiazepines	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.002	0.998	0.000
F05.8 Other delirium	0.002	0.998	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.002	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
L60.8 Other nail disorders	0.002	0.998	0.000
R49 Voice disturbances	0.002	0.998	0.000
B37.3 Candidiasis of vulva and vagina	0.002	0.998	0.000
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
O81.4 Vacuum extractor delivery	0.002	0.998	0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
I74.5 Embolism and thrombosis of iliac artery	0.000	0.998	0.002
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
F52.2 Failure of genital response	0.002	0.998	0.000
O82.8 Other single delivery by Caesarean section	0.002	0.998	0.000
O82.2 Delivery by Caesarean hysterectomy	0.002	0.998	0.000
O80.0 Spontaneous vertex delivery	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
I86.1 Scrotal varices	0.000	0.998	0.002
K85.9 Acute pancreatitis, unspecified	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
C64-C68 Malignant neoplasms of urinary tract	0.002	0.998	0.000
D23.5 Skin of trunk	0.002	0.998	0.000
I25.2 Old myocardial infarction	0.000	0.998	0.002
S51.9 Open wound of forearm, part unspecified	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.000	0.998	0.002
K85 Acute pancreatitis	0.002	0.998	0.000
S42.01 Fracture of clavicle (open)	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.002
F05.0 Delirium not superimposed on dementia, so described	0.002	0.998	0.000
R47 Speech disturbances, not elsewhere classified	0.002	0.998	0.000
S22.31 Fracture of rib (open)	0.002	0.998	0.000
X62.09 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified: Home: During unspecified activity	0.002	0.998	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
O81 Single delivery by forceps and vacuum extractor	0.002	0.998	0.000
F05.1 Delirium superimposed on dementia	0.002	0.998	0.000
I82.9 Embolism and thrombosis of unspecified vein	0.002	0.998	0.000
K85.8 Other acute pancreatitis	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.002	0.998	0.000
O80 Single spontaneous delivery	0.002	0.998	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.002	0.998	0.000
O80-O84 Delivery	0.002	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
R49.2 Hypernasality and hyponasality	0.002	0.998	0.000
R49.1 Aphonia	0.002	0.998	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.002	0.998	0.000
K12.2 Cellulitis and abscess of mouth	0.002	0.998	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
C71.2 Temporal lobe	0.000	0.998	0.002
S91 Open wound of ankle and foot	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
C68.0 Urethra	0.002	0.998	0.000
O82.9 Delivery by Caesarean section, unspecified	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
C71.7 Brain stem	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
K85.3 Drug-induced acute pancreatitis	0.002	0.998	0.000
K85.0 Idiopathic acute pancreatitis	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.002	0.998	0.000
L27 Dermatitis due to substances taken internally	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.000	0.998	0.002
D69.6 Thrombocytopenia, unspecified	0.000	0.998	0.002
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.998	0.002
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.998	0.002
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.998	0.002
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.998	0.002
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.998	0.002
G63.1 Polyneuropathy in neoplastic disease	0.000	0.998	0.002
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
O81.5 Delivery by combination of forceps and vacuum extractor	0.002	0.998	0.000
O81.3 Other and unspecified forceps delivery	0.002	0.998	0.000
O81.2 Mid-cavity forceps with rotation	0.002	0.998	0.000
O81.1 Mid-cavity forceps delivery	0.002	0.998	0.000
B37 Candidiasis	0.002	0.998	0.000
Z34 Supervision of normal pregnancy	0.002	0.998	0.000
K85.2 Alcohol-induced acute pancreatitis	0.002	0.998	0.000
R47.1 Dysarthria and anarthria	0.002	0.998	0.000
B37.2 Candidiasis of skin and nail	0.002	0.998	0.000
O80.1 Spontaneous breech delivery	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
O84 Multiple delivery	0.002	0.998	0.000
O83 Other assisted single delivery	0.002	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.002	0.998	0.000
C68.9 Urinary organ, unspecified	0.001	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.001	0.998	0.000
C68.1 Paraurethral glands	0.001	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.001	0.998	0.001
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters	0.002	0.998	0.000
O81.0 Low forceps delivery	0.001	0.998	0.000
R49.8 Other and unspecified voice disturbances	0.001	0.998	0.000
T39.0 Salicylates	0.001	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.001
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
T88.4 Failed or difficult intubation	0.000	0.998	0.002
M25.75 Osteophyte (Pelvic region and thigh)	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.001
N18.0 End-stage renal disease	0.000	0.998	0.002
O80.9 Single spontaneous delivery, unspecified	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.001	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.001	0.998	0.000
Z90.6 Acquired absence of other parts of urinary tract	0.002	0.998	0.000
O80.8 Other single spontaneous delivery	0.001	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.001	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.001	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.002	0.998	0.000
N03.9 Unspecified	0.000	0.998	0.002
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.998	0.001
L27.9 Dermatitis due to unspecified substance taken internally	0.001	0.998	0.000
L27.8 Dermatitis due to other substances taken internally	0.001	0.998	0.000
L27.2 Dermatitis due to ingested food	0.001	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.001
E23.2 Diabetes insipidus	0.002	0.998	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.001	0.998	0.000
B37.7 Candidal septicaemia	0.001	0.998	0.000
B37.6 Candidal endocarditis	0.001	0.998	0.000
B37.5 Candidal meningitis	0.001	0.998	0.000
B37.4 Candidiasis of other urogenital sites	0.001	0.998	0.000
D10.0 Lip	0.001	0.998	0.000
Y52.1 Calcium-channel blockers	0.001	0.998	0.000
H27.0 Aphakia	0.001	0.998	0.000
N76.8 Other specified inflammation of vagina and vulva	0.001	0.999	0.000
O83.9 Assisted single delivery, unspecified	0.001	0.999	0.000
O83.8 Other specified assisted single delivery	0.001	0.999	0.000
O83.4 Destructive operation for delivery	0.001	0.999	0.000
O83.3 Delivery of viable foetus in abdominal pregnancy	0.001	0.999	0.000
O83.2 Other manipulation-assisted delivery	0.001	0.999	0.000
O83.1 Other assisted breech delivery	0.001	0.999	0.000
O83.0 Breech extraction	0.001	0.999	0.000
O84.9 Multiple delivery, unspecified	0.001	0.999	0.000
O84.8 Other multiple delivery	0.001	0.999	0.000
O84.2 Multiple delivery, all by Caesarean section	0.001	0.999	0.000
O84.1 Multiple delivery, all by forceps and vacuum extractor	0.001	0.999	0.000
O84.0 Multiple delivery, all spontaneous	0.001	0.999	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.001	0.999	0.000
A63.0 Anogenital (venereal) warts	0.000	0.999	0.001
Y52.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
Z39.0 Care and examination immediately after delivery	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.001	0.999	0.000
F09 Unspecified organic or symptomatic mental disorder	0.001	0.999	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
C16.0 Cardia	0.000	0.999	0.001
Y48.4 Anaesthetic, unspecified	0.001	0.999	0.000
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
C16 Malignant neoplasm of stomach	0.000	0.999	0.001
F52.9 Unspecified sexual dysfunction, not caused by organic disorder or disease	0.001	0.999	0.000
F52.8 Other sexual dysfunction, not caused by organic disorder or disease	0.001	0.999	0.000
F52.7 Excessive sexual drive	0.001	0.999	0.000
F52.6 Nonorganic dyspareunia	0.001	0.999	0.000
F52.5 Nonorganic vaginismus	0.001	0.999	0.000
F52.4 Premature ejaculation	0.001	0.999	0.000
F52.3 Orgasmic dysfunction	0.001	0.999	0.000
F52.1 Sexual aversion and lack of sexual enjoyment	0.001	0.999	0.000
F52.0 Lack or loss of sexual desire	0.001	0.999	0.000
R47.0 Dysphasia and aphasia	0.001	0.999	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
Y52.7 Peripheral vasodilators	0.001	0.999	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.999	0.000
Z39 Postpartum care and examination	0.001	0.999	0.000
K12 Stomatitis and related lesions	0.001	0.999	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.001	0.999	0.000
Z49.1 Extracorporeal dialysis	0.000	0.999	0.001
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.001	0.999	0.000
B37.1 Pulmonary candidiasis	0.001	0.999	0.000
C69.3 Choroid	0.000	0.999	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.999	0.001
R48.8 Other and unspecified symbolic dysfunctions	0.001	0.999	0.000
R48.2 Apraxia	0.001	0.999	0.000
R48.1 Agnosia	0.001	0.999	0.000
R48.0 Dyslexia and alexia	0.001	0.999	0.000
F01 Vascular dementia	0.001	0.999	0.000
K12.0 Recurrent oral aphthae	0.001	0.999	0.000
N76.3 Subacute and chronic vulvitis	0.001	0.999	0.000
Y54.7 Agents affecting calcification	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
B25.9 Cytomegaloviral disease, unspecified	0.001	0.999	0.000
C16.3 Pyloric antrum	0.000	0.999	0.001
N02.9 Unspecified	0.000	0.999	0.001
C16.8 Overlapping lesion of stomach	0.000	0.999	0.001
C16.6 Greater curvature of stomach, unspecified	0.000	0.999	0.001
C16.4 Pylorus	0.000	0.999	0.001
C16.2 Body of stomach	0.000	0.999	0.001
C16.1 Fundus of stomach	0.000	0.999	0.001
D10.1 Tongue	0.001	0.999	0.000
D69.5 Secondary thrombocytopenia	0.000	0.999	0.001
F01.9 Vascular dementia, unspecified	0.001	0.999	0.000
N76.6 Ulceration of vulva	0.001	0.999	0.000
R27.0 Ataxia, unspecified	0.001	0.999	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
X60-X84 Intentional self-harm	0.001	0.999	0.000
D68.6 Other Thrombophilia	0.000	0.999	0.001
D72.1 Eosinophilia	0.000	0.999	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.1 Postencephalitic syndrome	0.001	0.999	0.000
F07.0 Organic personality disorder	0.001	0.999	0.000
Y54.4 Loop [high-ceiling] diuretics	0.001	0.999	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.001	0.999	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.001	0.999	0.000
N02.8 Other	0.000	0.999	0.001
N18.5 Chronic kidney disease, stage 5	0.000	0.999	0.001
R25.1 Tremor, unspecified	0.001	0.999	0.000
B91 Sequelae of poliomyelitis	0.000	0.999	0.001
D72 Other disorders of white blood cells	0.000	0.999	0.001
L29.0 Pruritus ani	0.001	0.999	0.000
W07.9 Unspecified place	0.001	0.999	0.000
D69.9 Haemorrhagic condition, unspecified	0.000	0.999	0.001
F01.8 Other vascular dementia	0.001	0.999	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.001	0.999	0.000
F01.2 Subcortical vascular dementia	0.001	0.999	0.000
F01.1 Multi-infarct dementia	0.001	0.999	0.000
F01.0 Vascular dementia of acute onset	0.001	0.999	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.999	0.000
F06.5 Organic dissociative disorder	0.001	0.999	0.000
F06.4 Organic anxiety disorder	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.999	0.000
F06.1 Organic catatonic disorder	0.001	0.999	0.000
F06.0 Organic hallucinosis	0.001	0.999	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.001	0.999	0.000
F50.0 Anorexia nervosa	0.001	0.999	0.000
Y57.9 Drug or medicament, unspecified	0.001	0.999	0.000
Z39.2 Routine postpartum follow-up	0.001	0.999	0.000
D68 Other coagulation defects	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
B37.0 Candidal stomatitis	0.001	0.999	0.000
R52.9 Pain, unspecified	0.000	0.999	0.001
F02 Dementia in other diseases classified elsewhere	0.001	0.999	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.000	0.999	0.001
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.999	0.001
I82.8 Embolism and thrombosis of other specified veins	0.001	0.999	0.000
T88.5 Other complications of anaesthesia	0.000	0.999	0.001
Y54.9 Mineral salts, not elsewhere classified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations