TreeWAS – Variant ID: rs11615274

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E21.3 Hyperparathyroidism, unspecified	0.024	0.976	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.023	0.977	0.000
E21.0 Primary hyperparathyroidism	0.021	0.979	0.000
E20-E35 Disorders of other endocrine glands	0.020	0.980	0.000
E27 Other disorders of adrenal gland	0.020	0.980	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.020	0.980	0.000
E28 Ovarian dysfunction	0.019	0.981	0.000
E28.2 Polycystic ovarian syndrome	0.019	0.981	0.000
S00.8 Superficial injury of other parts of head	0.019	0.981	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.018	0.982	0.000
E22 Hyperfunction of pituitary gland	0.018	0.982	0.000
E27.8 Other specified disorders of adrenal gland	0.018	0.982	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.017	0.983	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.017	0.983	0.000
E21.2 Other hyperparathyroidism	0.017	0.983	0.000
E21.4 Other specified disorders of parathyroid gland	0.017	0.983	0.000
E24 Cushing's syndrome	0.016	0.984	0.000
E35 Disorders of endocrine glands in diseases classified elsewhere	0.015	0.985	0.000
E32 Diseases of thymus	0.015	0.985	0.000
E31 Polyglandular dysfunction	0.015	0.985	0.000
E30 Disorders of puberty, not elsewhere classified	0.015	0.985	0.000
E25 Adrenogenital disorders	0.015	0.985	0.000
E27.5 Adrenomedullary hyperfunction	0.015	0.985	0.000
E27.0 Other adrenocortical overactivity	0.015	0.985	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.015	0.985	0.000
E26 Hyperaldosteronism	0.015	0.985	0.000
E22.0 Acromegaly and pituitary gigantism	0.014	0.985	0.000
E20 Hypoparathyroidism	0.014	0.985	0.000
E27.2 Addisonian crisis	0.014	0.985	0.000
E28.9 Ovarian dysfunction, unspecified	0.014	0.986	0.000
E28.8 Other ovarian dysfunction	0.014	0.986	0.000
E28.1 Androgen excess	0.014	0.986	0.000
E28.0 Oestrogen excess	0.014	0.986	0.000
E27.1 Primary adrenocortical insufficiency	0.013	0.987	0.000
E22.1 Hyperprolactinaemia	0.013	0.987	0.000
E28.3 Primary ovarian failure	0.013	0.987	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.013	0.987	0.000
E22.8 Other hyperfunction of pituitary gland	0.013	0.987	0.000
E27.9 Disorder of adrenal gland, unspecified	0.012	0.987	0.000
E24.0 Pituitary-dependent Cushing's disease	0.012	0.988	0.000
E34 Other endocrine disorders	0.012	0.988	0.000
E24.9 Cushing's syndrome, unspecified	0.012	0.988	0.000
E24.8 Other Cushing's syndrome	0.011	0.989	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.011	0.989	0.000
E24.3 Ectopic ACTH syndrome	0.011	0.989	0.000
E24.1 Nelson's syndrome	0.011	0.989	0.000
E29 Testicular dysfunction	0.011	0.989	0.000
N39.9 Disorder of urinary system, unspecified	0.011	0.989	0.000
E24.2 Drug-induced Cushing's syndrome	0.011	0.989	0.000
E25.9 Adrenogenital disorder, unspecified	0.011	0.989	0.000
E25.8 Other adrenogenital disorders	0.011	0.989	0.000
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.011	0.989	0.000
E30.9 Disorder of puberty, unspecified	0.011	0.989	0.000
E30.8 Other disorders of puberty	0.011	0.989	0.000
E30.1 Precocious puberty	0.011	0.989	0.000
E30.0 Delayed puberty	0.011	0.989	0.000
E31.9 Polyglandular dysfunction, unspecified	0.011	0.989	0.000
E31.8 Other polyglandular dysfunction	0.011	0.989	0.000
E31.1 Polyglandular hyperfunction	0.011	0.989	0.000
E31.0 Autoimmune polyglandular failure	0.011	0.989	0.000
E32.9 Disease of thymus, unspecified	0.011	0.989	0.000
E32.8 Other diseases of thymus	0.011	0.989	0.000
E32.1 Abscess of thymus	0.011	0.989	0.000
E32.0 Persistent hyperplasia of thymus	0.011	0.989	0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.011	0.989	0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.011	0.989	0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.011	0.989	0.000
E26.0 Primary hyperaldosteronism	0.011	0.989	0.000
E26.8 Other hyperaldosteronism	0.011	0.989	0.000
E26.1 Secondary hyperaldosteronism	0.011	0.989	0.000
E20.8 Other hypoparathyroidism	0.010	0.989	0.000
E20.1 Pseudohypoparathyroidism	0.010	0.989	0.000
E20.0 Idiopathic hypoparathyroidism	0.010	0.989	0.000
E26.9 Hyperaldosteronism, unspecified	0.010	0.990	0.000
E20.9 Hypoparathyroidism, unspecified	0.010	0.990	0.000
E34.8 Other specified endocrine disorders	0.009	0.990	0.000
E23 Hypofunction and other disorders of pituitary gland	0.009	0.991	0.000
E34.5 Androgen resistance syndrome	0.009	0.991	0.000
E34.4 Constitutional tall stature	0.009	0.991	0.000
E34.3 Short stature, not elsewhere classified	0.009	0.991	0.000
E34.2 Ectopic hormone secretion, not elsewhere classified	0.009	0.991	0.000
E34.1 Other hypersecretion of intestinal hormones	0.009	0.991	0.000
E29.9 Testicular dysfunction, unspecified	0.008	0.992	0.000
E29.8 Other testicular dysfunction	0.008	0.992	0.000
E29.0 Testicular hyperfunction	0.008	0.992	0.000
Z88.5 Personal history of allergy to narcotic agent	0.008	0.992	0.000
D37.5 Rectum	0.000	0.992	0.008
H92.0 Otalgia	0.000	0.992	0.008
E34.0 Carcinoid syndrome	0.007	0.993	0.000
E23.6 Other disorders of pituitary gland	0.007	0.993	0.000
N32.1 Vesicointestinal fistula	0.000	0.993	0.007
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.007	0.993	0.000
E23.1 Drug-induced hypopituitarism	0.007	0.993	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.993	0.007
D37.0 Lip, oral cavity and pharynx	0.000	0.993	0.007
E23.7 Disorder of pituitary gland, unspecified	0.007	0.993	0.000
M19.93 Arthrosis, unspecified (Forearm)	0.007	0.993	0.000
D37.1 Stomach	0.000	0.994	0.006
E34.9 Endocrine disorder, unspecified	0.006	0.994	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.994	0.006
E23.2 Diabetes insipidus	0.006	0.994	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.006	0.994	0.000
D37.3 Appendix	0.000	0.994	0.006
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.994	0.006
D37.9 Digestive organ, unspecified	0.000	0.995	0.005
H33.3 Retinal breaks without detachment	0.000	0.995	0.005
D37.7 Other digestive organs	0.000	0.995	0.005
D37.2 Small intestine	0.000	0.995	0.005
E29.1 Testicular hypofunction	0.004	0.995	0.000
Z83.4 Family history of other endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.004	0.996	0.000
H92 Otalgia and effusion of ear	0.000	0.996	0.004
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.004	0.996	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.996	0.004
H92.1 Otorrhoea	0.000	0.996	0.004
K29.4 Chronic atrophic gastritis	0.000	0.996	0.004
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.996	0.004
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.996	0.004
C18.0 Caecum	0.000	0.996	0.004
Z04.1 Examination and observation following transport accident	0.004	0.996	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.004	0.996	0.000
E23.0 Hypopituitarism	0.004	0.996	0.000
I72.0 Aneurysm of carotid artery	0.004	0.996	0.000
Q51.3 Bicornate uterus	0.000	0.996	0.004
G61.0 Guillain-Barre syndrome	0.000	0.996	0.004
S83.7 Injury to multiple structures of knee	0.004	0.996	0.000
Z04.3 Examination and observation following other accident	0.003	0.997	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.003	0.997	0.000
Z04 Examination and observation for other reasons	0.003	0.997	0.000
S83.1 Dislocation of knee	0.003	0.997	0.000
S83.0 Dislocation of patella	0.003	0.997	0.000
Y44.2 Anticoagulants	0.003	0.997	0.000
N36.0 Urethral fistula	0.000	0.997	0.003
S83.3 Tear of articular cartilage of knee, current	0.003	0.997	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.997	0.003
Z04.9 Examination and observation for unspecified reason	0.003	0.997	0.000
Z04.6 General psychiatric examination, requested by authority	0.003	0.997	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.000	0.997	0.003
H74.4 Polyp of middle ear	0.000	0.997	0.003
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.997	0.003
H92.2 Otorrhagia	0.000	0.997	0.003
K91.3 Postoperative intestinal obstruction	0.000	0.997	0.003
Z04.4 Examination and observation following alleged rape and seduction	0.003	0.997	0.000
Z04.2 Examination and observation following work accident	0.003	0.997	0.000
Z04.0 Blood-alcohol and blood-drug test	0.003	0.997	0.000
N48.9 Disorder of penis, unspecified	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.997	0.003
Q51.2 Other doubling of uterus	0.000	0.997	0.003
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.003	0.997	0.000
N36.1 Urethral diverticulum	0.000	0.997	0.003
Z04.5 Examination and observation following other inflicted injury	0.002	0.997	0.000
Y44 Agents primarily affecting blood constituents	0.003	0.997	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.002	0.997	0.000
E83.1 Disorders of iron metabolism	0.003	0.997	0.000
D32.0 Cerebral meninges	0.002	0.998	0.000
N36 Other disorders of urethra	0.000	0.998	0.002
N36.2 Urethral caruncle	0.000	0.998	0.002
K91.4 Colostomy and enterostomy malfunction	0.000	0.998	0.002
Y44.5 Thrombolytic drugs	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.000	0.998	0.002
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.002
R30.9 Painful micturition, unspecified	0.000	0.998	0.002
R40.0 Somnolence	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
Q51.9 Congenital malformation of uterus and cervix, unspecified	0.000	0.998	0.002
Q51.7 Congenital fistulae between uterus and digestive and urinary tracts	0.000	0.998	0.002
Q51.6 Embryonic cyst of cervix	0.000	0.998	0.002
Q51.5 Agenesis and aplasia of cervix	0.000	0.998	0.002
Q51.1 Doubling of uterus with doubling of cervix and vagina	0.000	0.998	0.002
Q51.0 Agenesis and aplasia of uterus	0.000	0.998	0.002
Y54.4 Loop [high-ceiling] diuretics	0.002	0.998	0.000
S62.50 Fracture of thumb (closed)	0.002	0.998	0.000
Q51.4 Unicornate uterus	0.000	0.998	0.002
Y54.3 Benzothiadiazine derivatives	0.002	0.998	0.000
Z04.8 Examination and observation for other specified reasons	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.000	0.998	0.002
N64.4 Mastodynia	0.002	0.998	0.000
H47.2 Optic atrophy	0.000	0.998	0.002
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.002	0.998	0.000
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
W44.0 Home	0.002	0.998	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.002	0.998	0.000
Y44.7 Plasma substitutes	0.002	0.998	0.000
Y44.6 Natural blood and blood products	0.002	0.998	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.002	0.998	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.002	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.002	0.998	0.000
G56.0 Carpal tunnel syndrome	0.002	0.998	0.000
H74.1 Adhesive middle ear disease	0.000	0.998	0.002
E11.2 With renal complications	0.000	0.998	0.002
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.998	0.002
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
N36.3 Prolapsed urethral mucosa	0.000	0.998	0.002
R82.9 Other and unspecified abnormal finding in urine	0.002	0.998	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
N36.9 Urethral disorder, unspecified	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.998	0.002
G61.1 Serum neuropathy	0.000	0.998	0.002
Z82.3 Family history of stroke	0.002	0.998	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.000	0.998	0.002
K55.9 Vascular disorder of intestine, unspecified	0.000	0.998	0.002
R07.1 Chest pain on breathing	0.000	0.998	0.002
W44.8 Other specified place	0.002	0.998	0.000
Y54.8 Agents affecting uric acid metabolism	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.000	0.998	0.002
Q05.9 Spina bifida, unspecified	0.002	0.998	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
W44 Foreign body entering into or through eye or natural orifice	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
J39.2 Other diseases of pharynx	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
H40.2 Primary angle-closure glaucoma	0.002	0.998	0.000
H74.0 Tympanosclerosis	0.000	0.998	0.002
S83.2 Tear of meniscus, current	0.002	0.998	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.002	0.998	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.002	0.998	0.000
Z41.2 Routine and ritual circumcision	0.002	0.998	0.000
W22.2 School, other institution and public administrative area	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.000	0.998	0.002
Y54.7 Agents affecting calcification	0.002	0.998	0.000
D07.5 Prostate	0.002	0.998	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.002	0.998	0.000
I72.2 Aneurysm of renal artery	0.002	0.998	0.000
Y54.9 Mineral salts, not elsewhere classified	0.002	0.998	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.002	0.998	0.000
Y54.0 Mineralocorticoids	0.002	0.998	0.000
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.5 Disorders of other visual pathways	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
W44.9 Unspecified place	0.002	0.998	0.000
Z41 Procedures for purposes other than remedying health state	0.002	0.998	0.000
M62.55 Muscle wasting and atrophy, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
D37.4 Colon	0.000	0.998	0.002
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.998	0.002
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.998	0.002
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.000	0.998	0.002
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.000	0.998	0.002
F12.1 Harmful use	0.002	0.998	0.000
G24.5 Blepharospasm	0.000	0.998	0.002
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.998	0.002
K91.5 Postcholecystectomy syndrome	0.000	0.998	0.002
M62.50 Muscle wasting and atrophy, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.001
M62.5 Muscle wasting and atrophy, not elsewhere classified	0.002	0.998	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.998	0.001
Q50.3 Other congenital malformations of ovary	0.000	0.998	0.001
Q50.2 Congenital torsion of ovary	0.000	0.998	0.001
Q50.1 Developmental ovarian cyst	0.000	0.998	0.001
Q50.0 Congenital absence of ovary	0.000	0.998	0.001
W23.4 Street and highway	0.002	0.998	0.000
W44.5 Trade and service area	0.001	0.998	0.000
W44.7 Farm	0.001	0.998	0.000
W44.6 Industrial and construction area	0.001	0.998	0.000
W44.4 Street and highway	0.001	0.998	0.000
W44.3 Sports and athletics area	0.001	0.998	0.000
W44.2 School, other institution and public administrative area	0.001	0.998	0.000
W44.1 Residential institution	0.001	0.998	0.000
G56.8 Other mononeuropathies of upper limb	0.002	0.998	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.000	0.998	0.002
M48.02 Spinal stenosis (Cervical region)	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.002	0.998	0.000
G93.0 Cerebral cysts	0.000	0.998	0.002
W23.3 Sports and athletics area	0.001	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.998	0.002
W44.99 Foreign body entering into or through eye or natural orifice, Unspecified place , During unspecified activity	0.001	0.998	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.000	0.998	0.002
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.001
G25.3 Myoclonus	0.000	0.998	0.002
K50.9 Crohn's disease, unspecified	0.000	0.998	0.002
Q89.2 Congenital malformations of other endocrine glands	0.000	0.998	0.001
K50 Crohn's disease [regional enteritis]	0.000	0.998	0.002
Q50-Q56 Congenital malformations of genital organs	0.000	0.998	0.001
K91.1 Postgastric surgery syndromes	0.000	0.998	0.001
Q05.7 Lumbar spina bifida without hydrocephalus	0.001	0.998	0.000
W23 Caught, crushed, jammed or pinched in or between objects	0.001	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.001
I72 Other aneurysm	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
M48.07 Spinal stenosis (Lumbosacral region)	0.001	0.998	0.000
M62.59 Muscle wasting and atrophy, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.000	0.998	0.001
K50.1 Crohn's disease of large intestine	0.000	0.998	0.002
V19.8 Pedal cyclist [any] injured in other specified transport accidents	0.001	0.998	0.000
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.001	0.998	0.000
Z41.3 Ear piercing	0.001	0.998	0.000
Z41.0 Hair transplant	0.001	0.998	0.000
Q05 Spina bifida	0.001	0.998	0.000
N36.8 Other specified disorders of urethra	0.000	0.999	0.001
Q64.7 Other congenital malformations of bladder and urethra	0.001	0.999	0.000
I72.9 Aneurysm of unspecified site	0.001	0.999	0.000
W24.9 Unspecified place	0.001	0.999	0.000
M62.58 Muscle wasting and atrophy, not elsewhere classified (Other)	0.001	0.999	0.000
M62.57 Muscle wasting and atrophy, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M62.54 Muscle wasting and atrophy, not elsewhere classified (Hand)	0.001	0.999	0.000
M62.53 Muscle wasting and atrophy, not elsewhere classified (Forearm)	0.001	0.999	0.000
M62.52 Muscle wasting and atrophy, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M62.51 Muscle wasting and atrophy, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
W44.59 Foreign body entering into or through eye or natural orifice; Trade and service area;During unspecified activity	0.001	0.999	0.000
Y54.5 Other diuretics	0.001	0.999	0.000
A16.9 Respiratory tuberculosis unspecified, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.8 Other respiratory tuberculosis, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.7 Primary respiratory tuberculosis without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.5 Tuberculous pleurisy, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.4 Tuberculosis of larynx, trachea and bronchus, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.3 Tuberculosis of intrathoracic lymph nodes, without mention of bacteriological or histological confirmation	0.001	0.999	0.000
A16.1 Tuberculosis of lung, bacteriological and histological examination not done	0.001	0.999	0.000
A16.0 Tuberculosis of lung, bacteriologically and histologically negative	0.001	0.999	0.000
M21.3 Wrist or foot drop (acquired)	0.001	0.999	0.000
M25.41 Effusion of joint (Shoulder region)	0.001	0.999	0.000
M62.56 Muscle wasting and atrophy, not elsewhere classified (Lower leg)	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.999	0.001
G25.5 Other chorea	0.000	0.999	0.001
G25.4 Drug-induced chorea	0.000	0.999	0.001
G25.1 Drug-induced tremor	0.000	0.999	0.001
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.001	0.999	0.000
J98.9 Respiratory disorder, unspecified	0.001	0.999	0.000
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
Q53 Undescended testicle	0.000	0.999	0.001
R05 Cough	0.000	0.999	0.001
W22 Striking against or struck by other objects	0.001	0.999	0.000
W23.9 Unspecified place	0.001	0.999	0.000
W23.8 Other specified place	0.001	0.999	0.000
W23.6 Industrial and construction area	0.001	0.999	0.000
W23.5 Trade and service area	0.001	0.999	0.000
W23.0 Home	0.001	0.999	0.000
W23.7 Farm	0.001	0.999	0.000
W23.1 Residential institution	0.001	0.999	0.000
Z09.8 Follow-up examination after other treatment for other conditions	0.001	0.999	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.000	0.999	0.001
Q52 Other congenital malformations of female genitalia	0.000	0.999	0.001
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.000	0.999	0.001
C90.0 Multiple myeloma	0.000	0.999	0.001
I72.6 Aneurysm and dissection of vertebral artery	0.001	0.999	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.001	0.999	0.000
I72.1 Aneurysm of artery of upper extremity	0.001	0.999	0.000
K50.8 Other Crohn's disease	0.000	0.999	0.001
Q61.2 Polycystic kidney, adult type	0.001	0.999	0.000
W27.2 School, other institution and public administrative area	0.001	0.999	0.000
M62 Other disorders of muscle	0.001	0.999	0.000
H47.1 Papilloedema, unspecified	0.000	0.999	0.001
J98.8 Other specified respiratory disorders	0.001	0.999	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.000	0.999	0.001
M62.6 Muscle strain	0.001	0.999	0.000
O02.1 Missed abortion	0.000	0.999	0.001
S00 Superficial injury of head	0.001	0.999	0.000
W24 Contact with lifting and transmission devices, not elsewhere classified	0.001	0.999	0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.001	0.999	0.000
M62.0 Diastasis of muscle	0.001	0.999	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.001	0.999	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.001	0.999	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.001	0.999	0.000
W23.2 School, other institution and public administrative area	0.001	0.999	0.000
M25.40 Effusion of joint (Multiple sites)	0.001	0.999	0.000
M62.08 Diastasis of muscle (Other)	0.001	0.999	0.000
M62.68 Muscle strain (Other)	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
M79.67 Pain in limb (Ankle and foot)	0.001	0.999	0.000
G25.2 Other specified forms of tremor	0.000	0.999	0.001
G58.8 Other specified mononeuropathies	0.001	0.999	0.000
Q62.2 Congenital megaloureter	0.001	0.999	0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck	0.001	0.999	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.000	0.999	0.001
M21.39 Wrist or foot drop (acquired)-Site unspec	0.001	0.999	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.001	0.999	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.001	0.999	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.001	0.999	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.001	0.999	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.001	0.999	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.001	0.999	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.001	0.999	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
F31.6 Bipolar affective disorder, current episode mixed	0.001	0.999	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.999	0.001
H04.2 Epiphora	0.000	0.999	0.001
J98.5 Diseases of mediastinum, not elsewhere classified	0.001	0.999	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.000	0.999	0.001
W21.9 Unspecified place	0.000	0.999	0.001
W22.3 Sports and athletics area	0.001	0.999	0.000
Q64 Other congenital malformations of urinary system	0.001	0.999	0.000
M25.44 Effusion of joint (Hand)	0.001	0.999	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
G24 Dystonia	0.000	0.999	0.001
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
G24.3 Spasmodic torticollis	0.000	0.999	0.001
Q53.9 Undescended testicle, unspecified	0.000	0.999	0.001
Q53.2 Undescended testicle, bilateral	0.000	0.999	0.001
Q53.0 Ectopic testis	0.000	0.999	0.001
Q56.4 Indeterminate sex, unspecified	0.000	0.999	0.001
Q56.3 Pseudohermaphroditism, unspecified	0.000	0.999	0.001
Q56.2 Female pseudohermaphroditism, not elsewhere classified	0.000	0.999	0.001
Q56.1 Male pseudohermaphroditism, not elsewhere classified	0.000	0.999	0.001
Q56.0 Hermaphroditism, not elsewhere classified	0.000	0.999	0.001
W22.8 Other specified place	0.001	0.999	0.000
W22.6 Industrial and construction area	0.001	0.999	0.000
W22.4 Street and highway	0.001	0.999	0.000
W22.0 Home	0.001	0.999	0.000
W22.7 Farm	0.001	0.999	0.000
W22.1 Residential institution	0.001	0.999	0.000
W27 Contact with nonpowered hand tool	0.001	0.999	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.001	0.999	0.000
W23.09 Caught, crushed, jammed or pinched in or between objects; Home; During unspecified activity	0.001	0.999	0.000
W23.08 Caught, crushed, jammed or pinched in or between objects; Home; While engaged in other specified activities	0.001	0.999	0.000
W23.03 Caught, crushed, jammed or pinched in or between objects; Home; While engaged in other types of work	0.001	0.999	0.000
W23.52 Caught, crushed, jammed or pinched in or between objects; Trade and service area;While working for income	0.001	0.999	0.000
W23.69 Caught, crushed, jammed or pinched in or between objects; Industrial and construction area ;During unspecified activity	0.001	0.999	0.000
W23.82 Caught, crushed, jammed or pinched in or between objects; Other specified places ;While working for income	0.001	0.999	0.000
W23.99 Caught, crushed, jammed or pinched in or between objects; Unspecified place ;During unspecified activity	0.001	0.999	0.000
W23.92 Caught, crushed, jammed or pinched in or between objects; Unspecified place ;While working for income	0.001	0.999	0.000
M62.4 Contracture of muscle	0.001	0.999	0.000
M62.3 Immobility syndrome (paraplegic)	0.001	0.999	0.000
M62.2 Ischaemic infarction of muscle	0.001	0.999	0.000
M62.1 Other rupture of muscle (nontraumatic)	0.001	0.999	0.000
Q52.9 Congenital malformation of female genitalia, unspecified	0.000	0.999	0.001
Q52.8 Other specified congenital malformations of female genitalia	0.000	0.999	0.001
Q52.7 Other congenital malformations of vulva	0.000	0.999	0.001
Q52.6 Congenital malformation of clitoris	0.000	0.999	0.001
Q52.4 Other congenital malformations of vagina	0.000	0.999	0.001
Q52.3 Imperforate hymen	0.000	0.999	0.001
Q52.2 Congenital rectovaginal fistula	0.000	0.999	0.001
Q52.1 Doubling of vagina	0.000	0.999	0.001
Q52.0 Congenital absence of vagina	0.000	0.999	0.001
Q53.1 Undescended testicle, unilateral	0.000	0.999	0.001
S00.4 Superficial injury of ear	0.001	0.999	0.000
W02.9 Unspecified place	0.001	0.999	0.000
W40.9 Unspecified place	0.001	0.999	0.000
Y04.8 Other specified place	0.001	0.999	0.000
W20-W49 Exposure to inanimate mechanical forces	0.001	0.999	0.000
M62.69 Muscle strain (Site unspecified)	0.001	0.999	0.000
M62.67 Muscle strain (Ankle and foot)	0.001	0.999	0.000
M62.66 Muscle strain (Lower leg)	0.001	0.999	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.001	0.999	0.000
M62.64 Muscle strain (Hand)	0.001	0.999	0.000
M62.63 Muscle strain (Forearm)	0.001	0.999	0.000
M62.62 Muscle strain (Upper arm)	0.001	0.999	0.000
M62.61 Muscle strain (Shoulder region)	0.001	0.999	0.000
M62.60 Muscle strain (Multiple sites)	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.001	0.999	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.000	0.999	0.001
M62.9 Disorder of muscle, unspecified	0.001	0.999	0.000
Q52.5 Fusion of labia	0.000	0.999	0.001
W24.8 Other specified place	0.001	0.999	0.000
W24.7 Farm	0.001	0.999	0.000
W24.6 Industrial and construction area	0.001	0.999	0.000
W24.5 Trade and service area	0.001	0.999	0.000
W24.4 Street and highway	0.001	0.999	0.000
W24.3 Sports and athletics area	0.001	0.999	0.000
W24.2 School, other institution and public administrative area	0.001	0.999	0.000
W24.1 Residential institution	0.001	0.999	0.000
W24.0 Home	0.001	0.999	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999	0.000
Q55 Other congenital malformations of male genital organs	0.000	0.999	0.001
W40 Explosion of other materials	0.001	0.999	0.000
M62.09 Diastasis of muscle (Site unspecified)	0.001	0.999	0.000
M62.07 Diastasis of muscle (Ankle and foot)	0.001	0.999	0.000
M62.06 Diastasis of muscle (Lower leg)	0.001	0.999	0.000
M62.05 Diastasis of muscle (Pelvic region and thigh)	0.001	0.999	0.000
M62.04 Diastasis of muscle (Hand)	0.001	0.999	0.000
M62.03 Diastasis of muscle (Forearm)	0.001	0.999	0.000
M62.02 Diastasis of muscle (Upper arm)	0.001	0.999	0.000
M62.01 Diastasis of muscle (Shoulder region)	0.001	0.999	0.000
M62.00 Diastasis of muscle (Multiple sites)	0.001	0.999	0.000
I72.3 Aneurysm of iliac artery	0.001	0.999	0.000
S00.0 Superficial injury of scalp	0.001	0.999	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
W28 Contact with powered lawn mower	0.001	0.999	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.001	0.999	0.000
D32.1 Spinal meninges	0.001	0.999	0.000
I86.4 Gastric varices	0.001	0.999	0.000
M25.4 Effusion of joint	0.001	0.999	0.000
Q64.9 Congenital malformation of urinary system, unspecified	0.001	0.999	0.000
Q64.8 Other specified congenital malformations of urinary system	0.001	0.999	0.000
Q64.6 Congenital diverticulum of bladder	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations