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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11643654
log Bayes Factor = 1.92054
Chromosome 16   position 51,183,728  (GRCh37) Explore rs11643654 on Ensembl!
Variant rs11643654 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E04.2 Non-toxic multinodular goitre
0.000 0.017 0.983
E04 Other non-toxic goitre
0.000 0.089 0.911
E04.9 Non-toxic goitre, unspecified
0.000 0.108 0.892
E04.1 Non-toxic single thyroid nodule
0.000 0.288 0.712
E04.8 Other specified non-toxic goitre
0.000 0.347 0.653
E00-E07 Disorders of thyroid gland
0.000 0.561 0.439
E04.0 Non-toxic diffuse goitre
0.000 0.575 0.425
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.630 0.370
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.667 0.333
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.676 0.324
E05.8 Other thyrotoxicosis
0.000 0.679 0.321
E07 Other disorders of thyroid
0.000 0.679 0.321
E06 Thyroiditis
0.000 0.684 0.316
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.685 0.315
E00 Congenital iodine-deficiency syndrome
0.000 0.685 0.315
E07.8 Other specified disorders of thyroid
0.000 0.710 0.290
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.730 0.270
E05.5 Thyroid crisis or storm
0.000 0.734 0.265
E05.4 Thyrotoxicosis factitia
0.000 0.734 0.265
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.734 0.265
E06.3 Autoimmune thyroiditis
0.000 0.762 0.238
E06.9 Thyroiditis, unspecified
0.000 0.766 0.233
E07.1 Dyshormogenetic goitre
0.000 0.770 0.230
E07.0 Hypersecretion of calcitonin
0.000 0.770 0.230
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.770 0.230
E06.5 Other chronic thyroiditis
0.000 0.772 0.228
E06.4 Drug-induced thyroiditis
0.000 0.773 0.227
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.773 0.227
E06.0 Acute thyroiditis
0.000 0.773 0.227
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.774 0.226
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.774 0.226
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.774 0.226
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.774 0.226
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.774 0.226
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.774 0.226
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.774 0.226
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.774 0.226
E03 Other hypothyroidism
0.000 0.787 0.213
E06.1 Subacute thyroiditis
0.000 0.793 0.207
Z96.1 Presence of intraocular lens
0.187 0.813 0.000
E03.8 Other specified hypothyroidism
0.000 0.817 0.183
E03.5 Myxoedema coma
0.000 0.847 0.153
E03.4 Atrophy of thyroid (acquired)
0.000 0.847 0.153
E03.3 Postinfectious hypothyroidism
0.000 0.847 0.153
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.852 0.148
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.853 0.146
E05.9 Thyrotoxicosis, unspecified
0.000 0.858 0.142
E03.1 Congenital hypothyroidism without goitre
0.000 0.865 0.135
E89.0 Postprocedural hypothyroidism
0.000 0.873 0.127
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.908 0.092
H43.3 Other vitreous opacities
0.084 0.916 0.000
H43 Disorders of vitreous body
0.081 0.919 0.000
E89.2 Postprocedural hypoparathyroidism
0.000 0.921 0.079
H43.8 Other disorders of vitreous body
0.076 0.924 0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.925 0.075
E89.4 Postprocedural ovarian failure
0.000 0.926 0.074
H43.1 Vitreous haemorrhage
0.072 0.928 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.929 0.070
H43.9 Disorder of vitreous body, unspecified
0.070 0.930 0.000
F31.9 Bipolar affective disorder, unspecified
0.000 0.932 0.068
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.934 0.066
E89.1 Postprocedural hypoinsulinaemia
0.000 0.934 0.065
F31 Bipolar affective disorder
0.000 0.936 0.064
E89.5 Postprocedural testicular hypofunction
0.000 0.936 0.064
H20.9 Iridocyclitis, unspecified
0.062 0.938 0.000
H43.2 Crystalline deposits in vitreous body
0.059 0.941 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.942 0.058
H43.0 Vitreous prolapse
0.058 0.942 0.000
E70-E90 Metabolic disorders
0.000 0.942 0.058
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.000 0.943 0.057
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.000 0.943 0.057
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.944 0.056
E88 Other metabolic disorders
0.000 0.950 0.050
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.000 0.950 0.050
F31.0 Bipolar affective disorder, current episode hypomanic
0.000 0.950 0.050
F31.7 Bipolar affective disorder, currently in remission
0.000 0.950 0.049
Z35.1 Supervision of pregnancy with history of abortive outcome
0.048 0.952 0.000
E79 Disorders of purine and pyrimidine metabolism
0.000 0.953 0.047
H20 Iridocyclitis
0.046 0.954 0.000
F30-F39 Mood [affective] disorders
0.000 0.954 0.046
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.000 0.954 0.046
E73 Lactose intolerance
0.000 0.955 0.045
E84 Cystic fibrosis
0.000 0.955 0.045
F31.6 Bipolar affective disorder, current episode mixed
0.000 0.955 0.045
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.956 0.044
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.000 0.956 0.044
E70 Disorders of aromatic amino-acid metabolism
0.000 0.957 0.043
E50-E64 Other nutritional deficiencies
0.001 0.958 0.042
E88.9 Metabolic disorder, unspecified
0.000 0.958 0.042
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.958 0.042
E77 Disorders of glycoprotein metabolism
0.000 0.958 0.041
E76 Disorders of glycosaminoglycan metabolism
0.000 0.958 0.041
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.958 0.041
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.958 0.041
E88.8 Other specified metabolic disorders
0.000 0.959 0.041
F33 Recurrent depressive disorder
0.000 0.959 0.041
F31.8 Other bipolar affective disorders
0.000 0.960 0.040
H20.0 Acute and subacute iridocyclitis
0.040 0.960 0.000
E72 Other disorders of amino-acid metabolism
0.000 0.961 0.039
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.961 0.039
F30 Manic episode
0.000 0.962 0.038
E61 Deficiency of other nutrient elements
0.000 0.962 0.038
F34 Persistent mood [affective] disorders
0.000 0.962 0.038
E88.2 Lipomatosis, not elsewhere classified
0.000 0.962 0.037
E61.1 Iron deficiency
0.000 0.963 0.037
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.963 0.037
E73.9 Lactose intolerance, unspecified
0.000 0.963 0.037
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.000 0.963 0.037
H35.8 Other specified retinal disorders
0.036 0.964 0.000
E84.9 Cystic fibrosis, unspecified
0.000 0.964 0.036
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.000 0.964 0.036
H43-H45 Disorders of vitreous body and globe
0.036 0.964 0.000
E89.3 Postprocedural hypopituitarism
0.000 0.964 0.036
E86 Volume depletion
0.000 0.964 0.036
E74 Other disorders of carbohydrate metabolism
0.000 0.965 0.035
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.000 0.965 0.035
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.965 0.035
H20.1 Chronic iridocyclitis
0.034 0.966 0.000
E75.5 Other lipid storage disorders
0.000 0.966 0.034
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.966 0.034
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.966 0.034
E79.1 Lesch-Nyhan syndrome
0.000 0.966 0.034
E40-E46 Malnutrition
0.000 0.966 0.034
H20.2 Lens-induced iridocyclitis
0.033 0.966 0.000
F39 Unspecified mood [affective] disorder
0.000 0.967 0.033
H20.8 Other iridocyclitis
0.033 0.967 0.000
E73.8 Other lactose intolerance
0.000 0.967 0.033
E73.1 Secondary lactase deficiency
0.000 0.967 0.033
E73.0 Congenital lactase deficiency
0.000 0.967 0.033
E56 Other vitamin deficiencies
0.001 0.967 0.032
F33.1 Recurrent depressive disorder, current episode moderate
0.000 0.967 0.033
E75.2 Other sphingolipidosis
0.000 0.967 0.032
E58 Dietary calcium deficiency
0.001 0.967 0.032
E84.8 Cystic fibrosis with other manifestations
0.000 0.967 0.032
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.967 0.032
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.967 0.032
E70.3 Albinism
0.000 0.968 0.032
E75.6 Lipid storage disorder, unspecified
0.000 0.968 0.032
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.968 0.032
E75.3 Sphingolipidosis, unspecified
0.000 0.968 0.032
E75.1 Other gangliosidosis
0.000 0.968 0.032
E75.0 GM2 gangliosidosis
0.000 0.968 0.032
F30.2 Mania with psychotic symptoms
0.000 0.968 0.032
E51 Thiamine deficiency
0.001 0.969 0.031
H35.5 Hereditary retinal dystrophy
0.031 0.969 0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.969 0.031
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.969 0.031
E70.2 Disorders of tyrosine metabolism
0.000 0.969 0.031
E70.1 Other hyperphenylalaninaemias
0.000 0.969 0.031
E70.0 Classical phenylketonuria
0.000 0.969 0.031
F34.1 Dysthymia
0.000 0.969 0.031
H35 Other retinal disorders
0.031 0.969 0.000
F30.0 Hypomania
0.000 0.969 0.031
E64 Sequelae of malnutrition and other nutritional deficiencies
0.001 0.969 0.030
E63 Other nutritional deficiencies
0.001 0.969 0.030
E50 Vitamin A deficiency
0.001 0.969 0.030
E60 Dietary zinc deficiency
0.001 0.969 0.030
E59 Dietary selenium deficiency
0.001 0.969 0.030
E52 Niacin deficiency [pellagra]
0.001 0.969 0.030
F34.0 Cyclothymia
0.000 0.970 0.030
F30.1 Mania without psychotic symptoms
0.000 0.970 0.030
E54 Ascorbic acid deficiency
0.001 0.970 0.030
E71.3 Disorders of fatty-acid metabolism
0.000 0.970 0.030
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.970 0.030
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.970 0.030
E71.0 Maple-syrup-urine disease
0.000 0.970 0.030
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.970 0.030
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.970 0.030
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.970 0.030
E76.2 Other mucopolysaccharidoses
0.000 0.970 0.030
E76.1 Mucopolysaccharidosis, type II
0.000 0.970 0.030
E76.0 Mucopolysaccharidosis, type I
0.000 0.970 0.030
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.970 0.030
E77.8 Other disorders of glycoprotein metabolism
0.000 0.970 0.030
E77.1 Defects in glycoprotein degradation
0.000 0.970 0.030
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.970 0.030
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.970 0.030
E65-E68 Obesity and other hyperalimentation
0.000 0.971 0.029
E80.4 Gilbert's syndrome
0.000 0.971 0.029
F33.0 Recurrent depressive disorder, current episode mild
0.000 0.971 0.029
F38 Other mood [affective] disorders
0.000 0.971 0.029
F33.9 Recurrent depressive disorder, unspecified
0.000 0.971 0.029
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.972 0.028
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.972 0.028
E72.5 Disorders of glycine metabolism
0.000 0.972 0.028
E72.4 Disorders of ornithine metabolism
0.000 0.972 0.028
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.972 0.028
E72.2 Disorders of urea cycle metabolism
0.000 0.972 0.028
F33.4 Recurrent depressive disorder, currently in remission
0.000 0.972 0.028
E61.9 Deficiency of nutrient element, unspecified
0.000 0.972 0.027
E61.8 Deficiency of other specified nutrient elements
0.000 0.972 0.027
E61.7 Deficiency of multiple nutrient elements
0.000 0.972 0.027
E61.6 Vanadium deficiency
0.000 0.972 0.027
E61.5 Molybdenum deficiency
0.000 0.972 0.027
E61.4 Chromium deficiency
0.000 0.972 0.027
E61.3 Manganese deficiency
0.000 0.972 0.027
E61.0 Copper deficiency
0.000 0.972 0.027
F30.8 Other manic episodes
0.000 0.972 0.028
F34.9 Persistent mood [affective] disorder, unspecified
0.000 0.972 0.028
F34.8 Other persistent mood [affective] disorders
0.000 0.972 0.028
E80.1 Porphyria cutanea tarda
0.000 0.972 0.027
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.973 0.027
E80.5 Crigler-Najjar syndrome
0.000 0.973 0.027
E80.3 Defects of catalase and peroxydase
0.000 0.973 0.027
E80.0 Hereditary erythropoietic porphyria
0.000 0.973 0.027
H35.2 Other proliferative retinopathy
0.026 0.974 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.974 0.026
E56.1 Deficiency of vitamin K
0.000 0.974 0.025
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.974 0.025
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.974 0.025
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.974 0.025
E74.2 Disorders of galactose metabolism
0.000 0.974 0.025
E74.1 Disorders of fructose metabolism
0.000 0.974 0.025
E74.0 Glycogen storage disease
0.000 0.974 0.025
F33.8 Other recurrent depressive disorders
0.000 0.974 0.025
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.025 0.975 0.000
E88.3 Tumour lysis syndrome
0.000 0.975 0.025
H35.6 Retinal haemorrhage
0.025 0.975 0.000
E15 Nondiabetic hypoglycaemic coma
0.000 0.975 0.025
H35.7 Separation of retinal layers
0.025 0.975 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.975 0.025
E72.0 Disorders of amino-acid transport
0.000 0.976 0.024
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.976 0.024
E45 Retarded development following protein-energy malnutrition
0.000 0.976 0.024
E43 Unspecified severe protein-energy malnutrition
0.000 0.976 0.024
E42 Marasmic kwashiorkor
0.000 0.976 0.024
E41 Nutritional marasmus
0.000 0.976 0.024
E40 Kwashiorkor
0.000 0.976 0.024
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.024 0.976 0.000
E56.9 Vitamin deficiency, unspecified
0.001 0.976 0.023
E56.8 Deficiency of other vitamins
0.001 0.976 0.023
E56.0 Deficiency of vitamin E
0.001 0.976 0.023
E87.5 Hyperkalaemia
0.000 0.976 0.024
H25.0 Senile incipient cataract
0.024 0.976 0.000
E51.2 Wernicke's encephalopathy
0.000 0.976 0.023
E80.6 Other disorders of bilirubin metabolism
0.000 0.976 0.023
E85 Amyloidosis
0.000 0.976 0.023
F30.9 Manic episode, unspecified
0.000 0.976 0.023
E87.7 Fluid overload
0.000 0.977 0.023
Z35 Supervision of high-risk pregnancy
0.023 0.977 0.000
E51.9 Thiamine deficiency, unspecified
0.001 0.977 0.022
E51.8 Other manifestations of thiamine deficiency
0.001 0.977 0.022
E51.1 Beriberi
0.001 0.977 0.022
H35.1 Retinopathy of prematurity
0.022 0.978 0.000
E50.9 Vitamin A deficiency, unspecified
0.001 0.978 0.022
E50.8 Other manifestations of vitamin A deficiency
0.001 0.978 0.022
E50.7 Other ocular manifestations of vitamin A deficiency
0.001 0.978 0.022
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.001 0.978 0.022
E50.5 Vitamin A deficiency with night blindness
0.001 0.978 0.022
E50.4 Vitamin A deficiency with keratomalacia
0.001 0.978 0.022
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.001 0.978 0.022
E50.2 Vitamin A deficiency with corneal xerosis
0.001 0.978 0.022
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.001 0.978 0.022
E50.0 Vitamin A deficiency with conjunctival xerosis
0.001 0.978 0.022
E63.9 Nutritional deficiency, unspecified
0.001 0.978 0.022
E63.8 Other specified nutritional deficiencies
0.001 0.978 0.022
E63.1 Imbalance of constituents of food intake
0.001 0.978 0.022
E63.0 Essential fatty acid [EFA] deficiency
0.001 0.978 0.022
E64.9 Sequelae of unspecified nutritional deficiency
0.001 0.978 0.022
E64.8 Sequelae of other nutritional deficiencies
0.001 0.978 0.022
E64.3 Sequelae of rickets
0.001 0.978 0.022
E64.2 Sequelae of vitamin C deficiency
0.001 0.978 0.022
E64.1 Sequelae of vitamin A deficiency
0.001 0.978 0.022
E64.0 Sequelae of protein-energy malnutrition
0.001 0.978 0.022
E80.2 Other porphyria
0.000 0.978 0.021
E67 Other hyperalimentation
0.000 0.979 0.021
E68 Sequelae of hyperalimentation
0.000 0.979 0.021
E61.2 Magnesium deficiency
0.001 0.979 0.021
Z35.0 Supervision of pregnancy with history of infertility
0.021 0.979 0.000
F38.1 Other recurrent mood [affective] disorders
0.000 0.979 0.021
E55 Vitamin D deficiency
0.001 0.979 0.020
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.020 0.980 0.000
E65 Localised adiposity
0.000 0.980 0.020
H15 Disorders of sclera
0.020 0.980 0.000
Z35.8 Supervision of other high-risk pregnancies
0.020 0.980 0.000
H35.9 Retinal disorder, unspecified
0.020 0.980 0.000
H35.0 Background retinopathy and retinal vascular changes
0.020 0.980 0.000
F38.0 Other single mood [affective] disorders
0.000 0.980 0.019
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.980 0.019
H17 Corneal scars and opacities
0.019 0.981 0.000
Chapter VII Diseases of the eye and adnexa
0.019 0.981 0.000
E87.4 Mixed disorder of acid-base balance
0.000 0.981 0.019
H30-H36 Disorders of choroid and retina
0.019 0.981 0.000
F38.8 Other specified mood [affective] disorders
0.000 0.981 0.018
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere
0.018 0.981 0.000
H45.1 Endophthalmitis in diseases classified elsewhere
0.018 0.981 0.000
Z35.4 Supervision of pregnancy with grand multiparity
0.018 0.982 0.000
E16 Other disorders of pancreatic internal secretion
0.000 0.982 0.018
H45.0 Vitreous haemorrhage in diseases classified elsewhere
0.018 0.982 0.000
E44.1 Mild protein-energy malnutrition
0.000 0.982 0.018
E44.0 Moderate protein-energy malnutrition
0.000 0.982 0.018
H44 Disorders of globe
0.018 0.982 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.017 0.982 0.000
Chapter V Mental and behavioural disorders
0.000 0.982 0.018
F60-F69 Disorders of adult personality and behaviour
0.000 0.983 0.017
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.983 0.017
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.983 0.017
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.983 0.017
H19.1 Herpesviral keratitis and keratoconjunctivitis
0.017 0.983 0.000
H15.8 Other disorders of sclera
0.017 0.983 0.000
E53 Deficiency of other B group vitamins
0.004 0.983 0.013
Z35.7 Supervision of high-risk pregnancy due to social problems
0.017 0.983 0.000
Z35.6 Supervision of very young primigravida
0.017 0.983 0.000
Z35.3 Supervision of pregnancy with history of insufficient antenatal care
0.017 0.983 0.000
F60 Specific personality disorders
0.000 0.983 0.017
Z35.9 Supervision of high-risk pregnancy, unspecified
0.017 0.983 0.000
E85.8 Other amyloidosis
0.000 0.984 0.016
E46 Unspecified protein-energy malnutrition
0.000 0.984 0.016
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.000 0.984 0.016
H46-H48 Disorders of optic nerve and visual pathways
0.016 0.984 0.000
H34 Retinal vascular occlusions
0.016 0.984 0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere
0.016 0.984 0.000
E67.8 Other specified hyperalimentation
0.000 0.984 0.015
E67.3 Hypervitaminosis D
0.000 0.984 0.015
E67.2 Megavitamin-B6 syndrome
0.000 0.984 0.015
E67.1 Hypercarotenaemia
0.000 0.984 0.015
E67.0 Hypervitaminosis A
0.000 0.984 0.015
H15.1 Episcleritis
0.015 0.985 0.000
F60.9 Personality disorder, unspecified
0.000 0.985 0.015
H17.9 Corneal scar and opacity, unspecified
0.015 0.985 0.000
E55.0 Rickets, active
0.001 0.985 0.015
H17.8 Other corneal scars and opacities
0.015 0.985 0.000
F69 Unspecified disorder of adult personality and behaviour
0.000 0.985 0.015
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere
0.015 0.985 0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere
0.015 0.985 0.000
F23 Acute and transient psychotic disorders
0.000 0.985 0.015
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere
0.015 0.985 0.000
E87.3 Alkalosis
0.000 0.985 0.015
H15.9 Disorder of sclera, unspecified
0.014 0.985 0.000
H15.0 Scleritis
0.014 0.986 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.014 0.986 0.000
E85.9 Amyloidosis, unspecified
0.000 0.986 0.014
H46 Optic neuritis
0.014 0.986 0.000
F29 Unspecified nonorganic psychosis
0.000 0.986 0.014
H17.1 Other central corneal opacity
0.014 0.986 0.000
H17.0 Adherent leukoma
0.014 0.986 0.000
F22 Persistent delusional disorders
0.000 0.986 0.014
F23.9 Acute and transient psychotic disorder, unspecified
0.000 0.986 0.014
H32 Chorioretinal disorders in diseases classified elsewhere
0.014 0.986 0.000
F60.7 Dependent personality disorder
0.000 0.986 0.014
H34.8 Other retinal vascular occlusions
0.014 0.986 0.000
E16.1 Other hypoglycaemia
0.000 0.986 0.014
E85.3 Secondary systemic amyloidosis
0.000 0.986 0.013
F60.3 Emotionally unstable personality disorder
0.000 0.986 0.014
H44.1 Other endophthalmitis
0.014 0.986 0.000
E85.4 Organ-limited amyloidosis
0.000 0.986 0.013
H44.7 Retained (old) intraocular foreign body, nonmagnetic
0.013 0.987 0.000
F60.5 Anankastic personality disorder
0.000 0.987 0.013
H25-H28 Disorders of lens
0.013 0.987 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.987 0.013
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.987 0.013
E16.4 Abnormal secretion of gastrin
0.000 0.987 0.013
E16.3 Increased secretion of glucagon
0.000 0.987 0.013
H25 Senile cataract
0.013 0.987 0.000
H44.5 Degenerated conditions of globe
0.013 0.987 0.000
F60.2 Dissocial personality disorder
0.000 0.987 0.013
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.987 0.013
F23.0 Acute polymorphic psychotic disorder without symptoms of schizophrenia
0.000 0.987 0.013
F60.8 Other specific personality disorders
0.000 0.987 0.013
H44.8 Other disorders of globe
0.013 0.987 0.000
H44.6 Retained (old) intraocular foreign body, magnetic
0.013 0.987 0.000
H44.3 Other degenerative disorders of globe
0.013 0.987 0.000
F68 Other disorders of adult personality and behaviour
0.000 0.987 0.013
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere
0.013 0.987 0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere
0.013 0.987 0.000
F61 Mixed and other personality disorders
0.000 0.987 0.013
H22.1 Iridocyclitis in other diseases classified elsewhere
0.013 0.987 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.000 0.987 0.013
F65 Disorders of sexual preference
0.000 0.987 0.013
F63 Habit and impulse disorders
0.000 0.987 0.013
F70-F79 Mental retardation
0.000 0.987 0.012
E53.1 Pyridoxine deficiency
0.003 0.988 0.009
E53.0 Riboflavin deficiency
0.003 0.988 0.009
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.012 0.988 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.000 0.988 0.012
F62 Enduring personality changes, not attributable to brain damage and disease
0.000 0.988 0.012
F60.4 Histrionic personality disorder
0.000 0.988 0.012
F60.1 Schizoid personality disorder
0.000 0.988 0.012
F43.1 Posttraumatic stress disorder
0.000 0.988 0.012
H34.1 Central retinal artery occlusion
0.012 0.988 0.000
H44.0 Purulent endophthalmitis
0.012 0.988 0.000
F64 Gender identity disorders
0.000 0.988 0.012
F22.0 Delusional disorder
0.000 0.988 0.012
F01 Vascular dementia
0.000 0.988 0.012
F28 Other nonorganic psychotic disorders
0.000 0.988 0.012
F24 Induced delusional disorder
0.000 0.988 0.012
F21 Schizotypal disorder
0.000 0.988 0.012
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.988 0.012
F22.9 Persistent delusional disorder, unspecified
0.000 0.988 0.012
F32 Depressive episode
0.000 0.988 0.012
H35.4 Peripheral retinal degeneration
0.012 0.988 0.000
H34.0 Transient retinal artery occlusion
0.011 0.988 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.011 0.988 0.000
H34.9 Retinal vascular occlusion, unspecified
0.011 0.988 0.000
E87.0 Hyperosmolality and hypernatraemia
0.000 0.989 0.011
F05 Delirium, not induced by alcohol and other psychoactive substances
0.000 0.989 0.011
H44.2 Degenerative myopia
0.011 0.989 0.000
E66 Obesity
0.000 0.989 0.011
N71.9 Inflammatory disease of uterus, unspecified
0.011 0.989 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.989 0.011
F23.8 Other acute and transient psychotic disorders
0.000 0.989 0.011
F23.2 Acute schizophrenia-like psychotic disorder
0.000 0.989 0.011
F43 Reaction to severe stress, and adjustment disorders
0.000 0.989 0.011
H40-H42 Glaucoma
0.011 0.989 0.000
E27 Other disorders of adrenal gland
0.000 0.989 0.011
F40-F48 Neurotic, stress-related and somatoform disorders
0.000 0.989 0.011
F01.9 Vascular dementia, unspecified
0.000 0.989 0.011
F60.6 Anxious [avoidant] personality disorder
0.000 0.989 0.010
E53.9 Vitamin B deficiency, unspecified
0.004 0.989 0.007
F22.8 Other persistent delusional disorders
0.000 0.990 0.010
R44.3 Hallucinations, unspecified
0.010 0.990 0.000
H25.8 Other senile cataract
0.010 0.990 0.000
H34.2 Other retinal artery occlusions
0.010 0.990 0.000
F23.1 Acute polymorphic psychotic disorder with symptoms of schizophrenia
0.000 0.990 0.010
H32.8 Other chorioretinal disorders in diseases classified elsewhere
0.010 0.990 0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
0.010 0.990 0.000
F80-F89 Disorders of psychological development
0.000 0.990 0.010
F95 Tic disorders
0.000 0.990 0.010
F01.1 Multi-infarct dementia
0.000 0.990 0.010
F99-F99 Unspecified mental disorder
0.000 0.990 0.010
E27.9 Disorder of adrenal gland, unspecified
0.000 0.990 0.010
H44.9 Disorder of globe, unspecified
0.010 0.990 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.010 0.990 0.000
E27.8 Other specified disorders of adrenal gland
0.000 0.990 0.010
H21 Other disorders of iris and ciliary body
0.010 0.990 0.000
H36 Retinal disorders in diseases classified elsewhere
0.010 0.990 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.010 0.990 0.000
H44.4 Hypotony of eye
0.010 0.990 0.000
H31 Other disorders of choroid
0.010 0.990 0.000
H30 Chorioretinal inflammation
0.009 0.990 0.000
F48 Other neurotic disorders
0.000 0.990 0.010
H49 Paralytic strabismus
0.010 0.990 0.000
F05.8 Other delirium
0.000 0.990 0.010
F44 Dissociative [conversion] disorders
0.000 0.990 0.010
F60.0 Paranoid personality disorder
0.000 0.990 0.009
F68.1 Intentional production or feigning of symptoms or disabilities, either physical or psychological [factitious disorder]
0.000 0.990 0.009
E20-E35 Disorders of other endocrine glands
0.000 0.990 0.010
F94 Disorders of social functioning with onset specific to childhood and adolescence
0.000 0.990 0.009
F93 Emotional disorders with onset specific to childhood
0.000 0.990 0.009
F92 Mixed disorders of conduct and emotions
0.000 0.990 0.009
F91 Conduct disorders
0.000 0.990 0.009
F90 Hyperkinetic disorders
0.000 0.990 0.009
H47.2 Optic atrophy
0.010 0.990 0.000
H49.1 Fourth [trochlear] nerve palsy
0.010 0.990 0.000
F05.0 Delirium not superimposed on dementia, so described
0.000 0.990 0.010
F79 Unspecified mental retardation
0.000 0.990 0.009
F68.8 Other specified disorders of adult personality and behaviour
0.000 0.990 0.009
F68.0 Elaboration of physical symptoms for psychological reasons
0.000 0.990 0.009
H18 Other disorders of cornea
0.009 0.990 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.991 0.009
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.000 0.991 0.009
E27.1 Primary adrenocortical insufficiency
0.000 0.991 0.009
F09 Unspecified organic or symptomatic mental disorder
0.000 0.991 0.009
F63.9 Habit and impulse disorder, unspecified
0.000 0.991 0.009
F63.8 Other habit and impulse disorders
0.000 0.991 0.009
F63.3 Trichotillomania
0.000 0.991 0.009
F63.2 Pathological stealing [kleptomania]
0.000 0.991 0.009
F63.1 Pathological fire-setting [pyromania]
0.000 0.991 0.009
F63.0 Pathological gambling
0.000 0.991 0.009
F65.9 Disorder of sexual preference, unspecified
0.000 0.991 0.009
F65.8 Other disorders of sexual preference
0.000 0.991 0.009
F65.6 Multiple disorders of sexual preference
0.000 0.991 0.009
F65.5 Sadomasochism
0.000 0.991 0.009
F65.4 Paedophilia
0.000 0.991 0.009
F65.3 Voyeurism
0.000 0.991 0.009
F65.2 Exhibitionism
0.000 0.991 0.009
F65.1 Fetishistic transvestism
0.000 0.991 0.009
F65.0 Fetishism
0.000 0.991 0.009
F66.9 Psychosexual development disorder, unspecified
0.000 0.991 0.009
F66.8 Other psychosexual development disorders
0.000 0.991 0.009
F66.2 Sexual relationship disorder
0.000 0.991 0.009
F66.1 Egodystonic sexual orientation
0.000 0.991 0.009
F66.0 Sexual maturation disorder
0.000 0.991 0.009
F23.3 Other acute predominantly delusional psychotic disorders
0.000 0.991 0.009
F32.3 Severe depressive episode with psychotic symptoms
0.000 0.991 0.009
F43.2 Adjustment disorders
0.000 0.991 0.009
F78 Other mental retardation
0.000 0.991 0.009
F73 Profound mental retardation
0.000 0.991 0.009
F72 Severe mental retardation
0.000 0.991 0.009
F71 Moderate mental retardation
0.000 0.991 0.009
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.991 0.009
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.000 0.991 0.009
F62.8 Other enduring personality changes
0.000 0.991 0.009
F62.1 Enduring personality change after psychiatric illness
0.000 0.991 0.009
F62.0 Enduring personality change after catastrophic experience
0.000 0.991 0.009
H21.5 Other adhesions and disruptions of iris and ciliary body
0.009 0.991 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.009 0.991 0.000
F02 Dementia in other diseases classified elsewhere
0.000 0.991 0.009
E27.2 Addisonian crisis
0.000 0.991 0.009
F64.9 Gender identity disorder, unspecified
0.000 0.991 0.009
F64.8 Other gender identity disorders
0.000 0.991 0.009
F64.2 Gender identity disorder of childhood
0.000 0.991 0.009
F64.1 Dual-role transvestism
0.000 0.991 0.009
F62.9 Enduring personality change, unspecified
0.000 0.991 0.009
H49.0 Third [oculomotor] nerve palsy
0.009 0.991 0.000
H53-H54 Visual disturbances and blindness
0.009 0.991 0.000
F01.8 Other vascular dementia
0.000 0.991 0.009
F01.3 Mixed cortical and subcortical vascular dementia
0.000 0.991 0.009
F01.2 Subcortical vascular dementia
0.000 0.991 0.009
F01.0 Vascular dementia of acute onset
0.000 0.991 0.009

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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