TreeWAS – Variant ID: rs116740811

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter XV Pregnancy, childbirth and the puerperium	1.000	0.000	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	1.000	0.000	0.000
# Top node	0.999	0.001	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001	0.000
O60-O75 Complications of labour and delivery	0.999	0.001	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.998	0.002	0.000
M65-M68 Disorders of synovium and tendon	0.996	0.004	0.000
M65 Synovitis and tenosynovitis	0.979	0.021	0.000
M45-M49 Spondylopathies	0.976	0.024	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.976	0.024	0.000
M67 Other disorders of synovium and tendon	0.965	0.035	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.963	0.037	0.000
O70 Perineal laceration during delivery	0.959	0.041	0.000
O46.9 Antepartum haemorrhage, unspecified	0.956	0.044	0.000
Chapter VI Diseases of the nervous system	0.954	0.046	0.000
M40-M43 Deforming dorsopathies	0.951	0.049	0.000
O70.1 Second degree perineal laceration during delivery	0.949	0.051	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.948	0.052	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.947	0.053	0.000
O63 Long labour	0.946	0.054	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.937	0.063	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.936	0.064	0.000
M46 Other inflammatory spondylopathies	0.936	0.064	0.000
O42 Premature rupture of membranes	0.931	0.069	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.929	0.071	0.000
O63.1 Prolonged second stage (of labour)	0.929	0.071	0.000
O40 Polyhydramnios	0.922	0.078	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.922	0.078	0.000
M41 Scoliosis	0.914	0.086	0.000
G30-G32 Other degenerative diseases of the nervous system	0.914	0.086	0.000
M46.9 Inflammatory spondylopathy, unspecified	0.907	0.093	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.905	0.095	0.000
S90-S99 Injuries to the ankle and foot	0.903	0.097	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.900	0.100	0.000
M65.3 Trigger finger	0.899	0.101	0.000
T18 Foreign body in alimentary tract	0.889	0.111	0.000
M41.9 Scoliosis, unspecified	0.888	0.112	0.000
S20-S29 Injuries to the thorax	0.886	0.114	0.000
M67.8 Other specified disorders of synovium and tendon	0.885	0.115	0.000
O30 Multiple gestation	0.884	0.116	0.000
O72 Postpartum haemorrhage	0.882	0.118	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.871	0.129	0.000
M67.1 Other contracture of tendon (sheath)	0.868	0.132	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.864	0.136	0.000
T42.4 Benzodiazepines	0.860	0.140	0.000
M00-M03 Infectious arthropathies	0.859	0.141	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.858	0.142	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.857	0.143	0.000
O32.1 Maternal care for breech presentation	0.856	0.144	0.000
Chapter XXI Factors influencing health status and contact with health services	0.856	0.144	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.856	0.144	0.000
S32 Fracture of lumbar spine and pelvis	0.855	0.145	0.000
O34.7 Maternal care for abnormality of vulva and perineum	0.853	0.147	0.000
S10-S19 Injuries to the neck	0.846	0.154	0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.844	0.156	0.000
M65.34 Trigger finger-Hand	0.842	0.158	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.840	0.160	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.839	0.161	0.000
O42.9 Premature rupture of membranes, unspecified	0.832	0.168	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.831	0.169	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.826	0.174	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.823	0.177	0.000
G57 Mononeuropathies of lower limb	0.823	0.177	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.821	0.179	0.000
Z75 Problems related to medical facilities and other health care	0.820	0.180	0.000
T66-T78 Other and unspecified effects of external causes	0.817	0.183	0.000
Chapter XX External causes of morbidity and mortality	0.815	0.185	0.000
O85-O92 Complications predominantly related to the puerperium	0.814	0.186	0.000
T18.1 Foreign body in oesophagus	0.814	0.186	0.000
G30 Alzheimer's disease	0.814	0.186	0.000
S91 Open wound of ankle and foot	0.813	0.187	0.000
M45 Ankylosing spondylitis	0.808	0.192	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.807	0.193	0.000
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.807	0.193	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.806	0.193	0.000
Q60-Q64 Congenital malformations of the urinary system	0.803	0.197	0.000
T00-T07 Injuries involving multiple body regions	0.802	0.198	0.000
S50-S59 Injuries to the elbow and forearm	0.802	0.198	0.000
O30.0 Twin pregnancy	0.801	0.199	0.000
M70-M79 Other soft tissue disorders	0.796	0.204	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.795	0.205	0.000
Z72 Problems related to lifestyle	0.793	0.207	0.000
O44 Placenta praevia	0.793	0.207	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.790	0.210	0.000
O66 Other obstructed labour	0.789	0.211	0.000
S20 Superficial injury of thorax	0.787	0.213	0.000
M60-M63 Disorders of muscles	0.786	0.214	0.000
O16 Unspecified maternal hypertension	0.782	0.218	0.000
T18.0 Foreign body in mouth	0.778	0.222	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.777	0.223	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.776	0.224	0.000
O34.1 Maternal care for tumour of corpus uteri	0.776	0.224	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.775	0.225	0.000
S92 Fracture of foot, except ankle	0.775	0.225	0.000
M41.99 Scoliosis, unspecified (Site unspecified)	0.773	0.227	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.773	0.227	0.000
O34.3 Maternal care for cervical incompetence	0.772	0.228	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.768	0.232	0.000
G70-G73 Diseases of myoneural junction and muscle	0.766	0.233	0.000
G31.8 Other specified degenerative diseases of nervous system	0.764	0.236	0.000
G57.6 Lesion of plantar nerve	0.763	0.237	0.000
M48 Other spondylopathies	0.762	0.238	0.000
O72.1 Other immediate postpartum haemorrhage	0.761	0.239	0.000
M00 Pyogenic arthritis	0.759	0.240	0.000
D80-D89 Certain disorders involving the immune mechanism	0.758	0.242	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.758	0.242	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.757	0.242	0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.757	0.243	0.000
M86-M90 Other osteopathies	0.757	0.243	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.755	0.245	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.755	0.245	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.753	0.247	0.000
S31 Open wound of abdomen, lower back and pelvis	0.753	0.247	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.752	0.248	0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.751	0.249	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.751	0.249	0.000
S32.4 Fracture of acetabulum	0.750	0.250	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.749	0.251	0.000
O61 Failed induction of labour	0.748	0.252	0.000
T79-T79 Certain early complications of trauma	0.747	0.253	0.000
G30.9 Alzheimer's disease, unspecified	0.742	0.258	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.742	0.258	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.740	0.260	0.000
Z37 Outcome of delivery	0.738	0.262	0.000
M47 Spondylosis	0.738	0.262	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.737	0.263	0.000
S91.3 Open wound of other parts of foot	0.736	0.264	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.734	0.266	0.000
O46.8 Other antepartum haemorrhage	0.734	0.266	0.000
Q43 Other congenital malformations of intestine	0.734	0.266	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.733	0.267	0.000
G56 Mononeuropathies of upper limb	0.732	0.268	0.000
Z73 Problems related to life-management difficulty	0.731	0.269	0.000
O32.2 Maternal care for transverse and oblique lie	0.729	0.271	0.000
M40 Kyphosis and lordosis	0.728	0.272	0.000
O62 Abnormalities of forces of labour	0.727	0.273	0.000
T43.2 Other and unspecified antidepressants	0.725	0.275	0.000
T45.0 Antiallergic and antiemetic drugs	0.725	0.275	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.722	0.278	0.000
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)	0.721	0.279	0.000
X60-X84 Intentional self-harm	0.721	0.279	0.000
Q00-Q07 Congenital malformations of the nervous system	0.720	0.280	0.000
O32.8 Maternal care for other malpresentation of foetus	0.719	0.281	0.000
Z37.0 Single live birth	0.717	0.283	0.000
O45 Premature separation of placenta [abruptio placentae]	0.717	0.283	0.000
O33 Maternal care for known or suspected disproportion	0.717	0.283	0.000
O31 Complications specific to multiple gestation	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.283	0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.716	0.284	0.000
O74 Complications of anaesthesia during labour and delivery	0.716	0.284	0.000
O71 Other obstetric trauma	0.716	0.284	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.716	0.284	0.000
O60 Preterm delivery	0.716	0.284	0.000
S51 Open wound of forearm	0.716	0.284	0.000
T33-T35 Frostbite	0.715	0.284	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.715	0.284	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.715	0.284	0.000
O73 Retained placenta and membranes, without haemorrhage	0.715	0.285	0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.714	0.286	0.000
M66 Spontaneous rupture of synovium and tendon	0.711	0.288	0.000
G31.0 Circumscribed brain atrophy	0.711	0.289	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.708	0.292	0.000
Chapter VII Diseases of the eye and adnexa	0.707	0.293	0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.705	0.295	0.000
M65.2 Calcific tendinitis	0.702	0.298	0.000
M65.1 Other infective (teno)synovitis	0.702	0.298	0.000
M65.0 Abscess of tendon sheath	0.702	0.298	0.000
S32.3 Fracture of ilium	0.701	0.299	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.700	0.299	0.000
M80-M85 Disorders of bone density and structure	0.700	0.300	0.000
M49 Spondylopathies in diseases classified elsewhere	0.700	0.300	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.699	0.300	0.000
Q80-Q89 Other congenital malformations	0.699	0.301	0.000
D55-D59 Haemolytic anaemias	0.698	0.302	0.000
W20-W49 Exposure to inanimate mechanical forces	0.697	0.303	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.696	0.303	0.000
O47 False labour	0.696	0.304	0.000
Y00-Y09 Assault	0.695	0.305	0.000
S30.1 Contusion of abdominal wall	0.695	0.305	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.694	0.305	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.694	0.306	0.000
M91-M94 Chondropathies	0.693	0.307	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.693	0.307	0.000
O32.4 Maternal care for high head at term	0.692	0.308	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.692	0.308	0.000
M67.4 Ganglion	0.692	0.308	0.000
M67.3 Transient synovitis	0.692	0.308	0.000
M67.0 Short Achilles tendon (acquired)	0.692	0.308	0.000
T78 Adverse effects, not elsewhere classified	0.691	0.309	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.691	0.309	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.691	0.309	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.691	0.309	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.691	0.309	0.000
T36 Poisoning by systemic antibiotics	0.691	0.309	0.000
Z76 Persons encountering health services in other circumstances	0.691	0.309	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.690	0.309	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.689	0.311	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.688	0.312	0.000
D86 Sarcoidosis	0.688	0.312	0.000
M00.9 Pyogenic arthritis, unspecified	0.688	0.312	0.000
M47.8 Other spondylosis	0.688	0.312	0.000
O70.3 Fourth degree perineal laceration during delivery	0.687	0.313	0.000
S19 Other and unspecified injuries of neck	0.687	0.313	0.000
M77 Other enthesopathies	0.687	0.313	0.000
G12 Spinal muscular atrophy and related syndromes	0.685	0.314	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.685	0.315	0.000
T17 Foreign body in respiratory tract	0.684	0.316	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.683	0.317	0.000
M42 Spinal osteochondrosis	0.682	0.318	0.000
O86 Other puerperal infections	0.682	0.318	0.000
G57.1 Meralgia paraesthetica	0.681	0.319	0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.679	0.320	0.000
S37 Injury of urinary and pelvic organs	0.679	0.320	0.000
S36 Injury of intra-abdominal organs	0.679	0.320	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.679	0.320	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.679	0.320	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.679	0.320	0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.679	0.321	0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.679	0.321	0.000
G59 Mononeuropathy in diseases classified elsewhere	0.679	0.321	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.678	0.321	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.677	0.323	0.000
S32.40 Fracture of acetabulum (closed)	0.675	0.325	0.000
Z72.0 Tobacco use	0.674	0.326	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.672	0.328	0.000
Q35-Q37 Cleft lip and cleft palate	0.672	0.328	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.672	0.328	0.000
D80 Immunodeficiency with predominantly antibody defects	0.672	0.328	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.672	0.328	0.000
M65.8 Other synovitis and tenosynovitis	0.671	0.329	0.000
T19 Foreign body in genito-urinary tract	0.671	0.329	0.000
T15 Foreign body on external eye	0.671	0.329	0.000
T16 Foreign body in ear	0.671	0.329	0.000
M46.8 Other specified inflammatory spondylopathies	0.671	0.329	0.000
M46.5 Other infective spondylopathies	0.671	0.329	0.000
M46.4 Discitis, unspecified	0.671	0.329	0.000
M46.3 Infection of intervertebral disk (pyogenic)	0.671	0.329	0.000
M46.2 Osteomyelitis of vertebra	0.671	0.329	0.000
M46.1 Sacro-iliitis, not elsewhere classified	0.671	0.329	0.000
M46.0 Spinal enthesopathy	0.671	0.329	0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.670	0.330	0.000
Z72.2 Drug use	0.670	0.330	0.000
G54 Nerve root and plexus disorders	0.669	0.331	0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.668	0.332	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.668	0.332	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.668	0.332	0.000
S32.0 Fracture of lumbar vertebra	0.667	0.333	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.666	0.334	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.666	0.334	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.666	0.334	0.000
O34.6 Maternal care for abnormality of vagina	0.666	0.334	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.666	0.334	0.000
O34.4 Maternal care for other abnormalities of cervix	0.666	0.334	0.000
O34.0 Maternal care for congenital malformation of uterus	0.666	0.334	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.665	0.334	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.665	0.335	0.000
G11 Hereditary ataxia	0.664	0.336	0.000
Q43.8 Other specified congenital malformations of intestine	0.664	0.336	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.661	0.339	0.000
O32.6 Maternal care for compound presentation	0.661	0.339	0.000
O32.3 Maternal care for face, brow and chin presentation	0.661	0.339	0.000
G20-G26 Extrapyramidal and movement disorders	0.659	0.340	0.001
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.660	0.340	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.659	0.341	0.000
T45.5 Anticoagulants	0.658	0.342	0.000
O66.0 Obstructed labour due to shoulder dystocia	0.657	0.343	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.657	0.343	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.657	0.343	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.657	0.343	0.000
G56.3 Lesion of radial nerve	0.656	0.344	0.000
S14 Injury of nerves and spinal cord at neck level	0.656	0.344	0.000
Z72.8 Other problems related to lifestyle	0.656	0.344	0.000
Z74 Problems related to care-provider dependency	0.656	0.344	0.000
S40-S49 Injuries to the shoulder and upper arm	0.656	0.344	0.000
M41.8 Other forms of scoliosis	0.655	0.344	0.000
M41.5 Other secondary scoliosis	0.655	0.344	0.000
M41.4 Neuromuscular scoliosis	0.655	0.344	0.000
M41.3 Thoracogenic scoliosis	0.655	0.344	0.000
M41.2 Other idiopathic scoliosis	0.655	0.344	0.000
M41.1 Juvenile idiopathic scoliosis	0.655	0.344	0.000
M41.0 Infantile idiopathic scoliosis	0.655	0.344	0.000
O48 Prolonged pregnancy	0.655	0.345	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.655	0.345	0.000
M43 Other deforming dorsopathies	0.654	0.346	0.000
O72.0 Third-stage haemorrhage	0.652	0.348	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.652	0.348	0.000
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)	0.650	0.349	0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)	0.650	0.349	0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)	0.650	0.349	0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)	0.650	0.349	0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)	0.650	0.349	0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)	0.650	0.349	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.650	0.350	0.000
O70.9 Perineal laceration during delivery, unspecified	0.649	0.351	0.000
T58 Toxic effect of carbon monoxide	0.649	0.351	0.000
Q61 Cystic kidney disease	0.649	0.351	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.648	0.351	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.648	0.351	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.648	0.351	0.000
T42.3 Barbiturates	0.648	0.351	0.000
T42.2 Succinimides and oxazolidinediones	0.648	0.351	0.000
T42.1 Iminostilbenes	0.648	0.351	0.000
T42.0 Hydantoin derivatives	0.648	0.351	0.000
Z75.8 Other problems related to medical facilities and other health care	0.648	0.351	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.648	0.352	0.000
S98 Traumatic amputation of ankle and foot	0.648	0.352	0.000
S97 Crushing injury of ankle and foot	0.648	0.352	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.648	0.352	0.000
S95 Injury of blood vessels at ankle and foot level	0.648	0.352	0.000
S94 Injury of nerves at ankle and foot level	0.648	0.352	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.646	0.354	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.645	0.354	0.000
O15 Eclampsia	0.645	0.355	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.645	0.355	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.645	0.355	0.000
M65.39 Trigger finger-Site unspec	0.645	0.355	0.000
M65.38 Trigger finger-Other	0.645	0.355	0.000
M65.37 Trigger finger-Ankle/foot	0.645	0.355	0.000
M65.36 Trigger finger-Lower leg	0.645	0.355	0.000
M65.35 Trigger finger-Pelvic/thigh	0.645	0.355	0.000
M65.33 Trigger finger-Forearm	0.645	0.355	0.000
M65.32 Trigger finger-Upper arm	0.645	0.355	0.000
M65.31 Trigger finger-Shldr region	0.645	0.355	0.000
M65.30 Trigger finger-Mult sites	0.645	0.355	0.000
O44.1 Placenta praevia with haemorrhage	0.644	0.355	0.000
T01 Open wounds involving multiple body regions	0.644	0.356	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.642	0.358	0.000
E20-E35 Disorders of other endocrine glands	0.641	0.359	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.639	0.361	0.000
T23 Burn and corrosion of wrist and hand	0.638	0.362	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.638	0.362	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.638	0.362	0.000
T18.5 Foreign body in anus and rectum	0.638	0.362	0.000
T18.4 Foreign body in colon	0.638	0.362	0.000
T18.3 Foreign body in small intestine	0.638	0.362	0.000
T18.2 Foreign body in stomach	0.638	0.362	0.000
S92.2 Fracture of other tarsal bone(s)	0.638	0.362	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.637	0.363	0.000
M76 Enthesopathies of lower limb, excluding foot	0.637	0.363	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.636	0.363	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.636	0.363	0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)	0.636	0.363	0.000
M41.92 Scoliosis, unspecified (Cervical region)	0.636	0.363	0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)	0.636	0.363	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.635	0.365	0.000
S26 Injury of heart	0.635	0.365	0.000
S25 Injury of blood vessels of thorax	0.635	0.365	0.000
S24 Injury of nerves and spinal cord at thorax level	0.635	0.365	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.635	0.365	0.000
S21 Open wound of thorax	0.635	0.365	0.000
O30.9 Multiple gestation, unspecified	0.634	0.366	0.000
O30.8 Other multiple gestation	0.634	0.366	0.000
O30.2 Quadruplet pregnancy	0.634	0.366	0.000
O30.1 Triplet pregnancy	0.634	0.366	0.000
M62 Other disorders of muscle	0.634	0.366	0.000
O72.3 Postpartum coagulation defects	0.632	0.367	0.000
T93 Sequelae of injuries of lower limb	0.630	0.370	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.630	0.370	0.000
S12 Fracture of neck	0.630	0.370	0.000
H55-H59 Other disorders of eye and adnexa	0.630	0.370	0.000
S59 Other and unspecified injuries of forearm	0.630	0.370	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.630	0.370	0.000
T51 Toxic effect of alcohol	0.630	0.370	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.629	0.371	0.000
Z75.3 Unavailability and inaccessibility of health-care facilities	0.628	0.372	0.000
M89 Other disorders of bone	0.628	0.372	0.000
X10-X19 Contact with heat and hot substances	0.627	0.373	0.000
Z35 Supervision of high-risk pregnancy	0.626	0.374	0.000
Q63 Other congenital malformations of kidney	0.625	0.375	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.624	0.375	0.000
G52 Disorders of other cranial nerves	0.624	0.376	0.000
S27 Injury of other and unspecified intrathoracic organs	0.623	0.376	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.623	0.377	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.623	0.377	0.000
G72 Other myopathies	0.623	0.377	0.000
O70.2 Third degree perineal laceration during delivery	0.623	0.377	0.000
Z75.4 Unavailability and inaccessibility of other helping agencies	0.623	0.377	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.622	0.378	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.622	0.378	0.000
O12.0 Gestational oedema	0.621	0.379	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.620	0.380	0.000
S30.0 Contusion of lower back and pelvis	0.619	0.380	0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.619	0.381	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.619	0.381	0.000
V80-V89 Other land transport accidents	0.617	0.383	0.000
S91.1 Open wound of toe(s) without damage to nail	0.617	0.383	0.000
S10 Superficial injury of neck	0.617	0.383	0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere	0.616	0.384	0.000
M02 Reactive arthropathies	0.616	0.384	0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere	0.616	0.384	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.616	0.384	0.000
L40-L45 Papulosquamous disorders	0.616	0.384	0.000
O75.9 Complication of labour and delivery, unspecified	0.615	0.385	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.615	0.385	0.000
O75.4 Other complications of obstetric surgery and procedures	0.615	0.385	0.000
O75.3 Other infection during labour	0.615	0.385	0.000
O75.1 Shock during or following labour and delivery	0.615	0.385	0.000
O75.0 Maternal distress during labour and delivery	0.615	0.385	0.000
X50-X57 Overexertion, travel and privation	0.615	0.385	0.000
D59 Acquired haemolytic anaemia	0.615	0.385	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.614	0.385	0.000
O97 Death from sequelae of direct obstetric causes	0.614	0.385	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.614	0.385	0.000
O95 Obstetric death of unspecified cause	0.614	0.385	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.614	0.385	0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.614	0.386	0.000
Z70 Counselling related to sexual attitude, behaviour and orientation	0.614	0.386	0.000
Z73.3 Stress, not elsewhere classified	0.613	0.387	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.613	0.387	0.000
S32.2 Fracture of coccyx	0.613	0.387	0.000
O87 Venous complications in the puerperium	0.611	0.389	0.000
T75 Effects of other external causes	0.611	0.389	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.611	0.389	0.000
H53-H54 Visual disturbances and blindness	0.610	0.390	0.000
M47.86 Other spondylosis (Lumbar region)	0.610	0.390	0.000
S22.4 Multiple fractures of ribs	0.608	0.392	0.000
O41 Other disorders of amniotic fluid and membranes	0.607	0.392	0.000
T40.2 Other opioids	0.607	0.393	0.000
S17 Crushing injury of neck	0.606	0.393	0.000
S15 Injury of blood vessels at neck level	0.606	0.393	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.606	0.393	0.000
S11 Open wound of neck	0.606	0.393	0.000
S18 Traumatic amputation at neck level	0.606	0.393	0.000
S16 Injury of muscle and tendon at neck level	0.606	0.393	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.606	0.394	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.606	0.394	0.000
W50-W64 Exposure to animate mechanical forces	0.605	0.394	0.000
V10-V19 Pedal cyclist injured in transport accident	0.605	0.395	0.000
Q50-Q56 Congenital malformations of genital organs	0.604	0.395	0.000
X20-X29 Contact with venomous animals and plants	0.604	0.396	0.000
O67.9 Intrapartum haemorrhage, unspecified	0.603	0.397	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.602	0.398	0.000
T45.8 Other primarily systemic and haematological agents	0.602	0.398	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.602	0.398	0.000
T45.6 Fibrinolysis-affecting drugs	0.602	0.398	0.000
T45.4 Iron and its compounds	0.602	0.398	0.000
T45.3 Enzymes, not elsewhere classified	0.602	0.398	0.000
T45.2 Vitamins, not elsewhere classified	0.602	0.398	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.602	0.398	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.602	0.398	0.000
M72 Fibroblastic disorders	0.602	0.398	0.000
G57.8 Other mononeuropathies of lower limb	0.602	0.398	0.000
O80-O84 Delivery	0.602	0.398	0.000
G81 Hemiplegia	0.602	0.398	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.602	0.398	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.601	0.399	0.000
T02 Fractures involving multiple body regions	0.601	0.399	0.000
V20-V29 Motorcycle rider injured in transport accident	0.601	0.399	0.000
Chapter I Certain infectious and parasitic diseases	0.600	0.400	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.600	0.400	0.000
D84 Other immunodeficiencies	0.599	0.401	0.000
T78.2 Anaphylactic shock, unspecified	0.599	0.401	0.000
Z37.2 Twins, both liveborn	0.598	0.402	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.597	0.403	0.000
O43 Placental disorders	0.597	0.403	0.000
Z71.8 Other specified counselling	0.596	0.404	0.000
S90 Superficial injury of ankle and foot	0.596	0.404	0.000
Q45 Other congenital malformations of digestive system	0.596	0.404	0.000
Q42 Congenital absence, atresia and stenosis of large intestine	0.596	0.404	0.000
Q41 Congenital absence, atresia and stenosis of small intestine	0.596	0.404	0.000
Q40 Other congenital malformations of upper alimentary tract	0.596	0.404	0.000
Q39 Congenital malformations of oesophagus	0.596	0.404	0.000
V40-V49 Car occupant injured in transport accident	0.595	0.405	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.595	0.405	0.000
M77.1 Lateral epicondylitis	0.595	0.405	0.000
Chapter XXII Codes for special purposes	0.593	0.407	0.000
T43.9 Psychotropic drug, unspecified	0.592	0.408	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.592	0.408	0.000
T43.6 Psychostimulants with abuse potential	0.592	0.408	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.592	0.408	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.592	0.408	0.000
S32.1 Fracture of sacrum	0.591	0.409	0.000
L40 Psoriasis	0.591	0.409	0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.591	0.409	0.000
O22 Venous complications in pregnancy	0.591	0.409	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.590	0.410	0.000
G14 Postpolio syndrome	0.590	0.410	0.000
G10 Huntington's disease	0.590	0.410	0.000
S32.30 Fracture of ilium (closed)	0.590	0.410	0.000
S29 Other and unspecified injuries of thorax	0.590	0.410	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.590	0.410	0.000
G57.5 Tarsal tunnel syndrome	0.590	0.410	0.000
G57.4 Lesion of medial popliteal nerve	0.590	0.410	0.000
G57.3 Lesion of lateral popliteal nerve	0.590	0.410	0.000
G57.2 Lesion of femoral nerve	0.590	0.410	0.000
G57.0 Lesion of sciatic nerve	0.590	0.410	0.000
S51.9 Open wound of forearm, part unspecified	0.590	0.410	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.589	0.411	0.000
S30.2 Contusion of external genital organs	0.589	0.411	0.000
S92.5 Fracture of other toe	0.588	0.411	0.000
Z75.9 Unspecified problem related to medical facilities and other health care	0.588	0.412	0.000
Z75.2 Other waiting period for investigation and treatment	0.588	0.412	0.000
Z75.0 Medical services not available in home	0.588	0.412	0.000
S56 Injury of muscle and tendon at forearm level	0.587	0.413	0.000
S20.2 Contusion of thorax	0.587	0.413	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.587	0.413	0.000
G12.2 Motor neuron disease	0.587	0.413	0.000
T74 Maltreatment syndromes	0.586	0.414	0.000
T73 Effects of other deprivation	0.586	0.414	0.000
T70 Effects of air pressure and water pressure	0.586	0.414	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations