TreeWAS – Variant ID: rs11677911

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86 Sarcoidosis	0.185	0.815	0.000
D86.0 Sarcoidosis of lung	0.184	0.816	0.000
D86.9 Sarcoidosis, unspecified	0.174	0.826	0.000
D86.3 Sarcoidosis of skin	0.160	0.840	0.000
D80-D89 Certain disorders involving the immune mechanism	0.156	0.844	0.000
D86.8 Sarcoidosis of other and combined sites	0.154	0.846	0.000
D80 Immunodeficiency with predominantly antibody defects	0.143	0.857	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.137	0.863	0.000
D84 Other immunodeficiencies	0.137	0.863	0.000
D84.9 Immunodeficiency, unspecified	0.123	0.877	0.000
D86.1 Sarcoidosis of lymph nodes	0.121	0.879	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.120	0.880	0.000
D83 Common variable immunodeficiency	0.120	0.880	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.118	0.882	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.116	0.884	0.000
D82 Immunodeficiency associated with other major defects	0.112	0.888	0.000
D81 Combined immunodeficiencies	0.112	0.888	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.105	0.895	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.104	0.896	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.103	0.897	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.103	0.897	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.103	0.897	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.103	0.897	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.103	0.897	0.000
D84.8 Other specified immunodeficiencies	0.100	0.900	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.098	0.902	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.097	0.903	0.000
D84.1 Defects in the complement system	0.096	0.904	0.000
D83.9 Common variable immunodeficiency, unspecified	0.094	0.905	0.000
D83.8 Other common variable immunodeficiencies	0.086	0.914	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.086	0.914	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.086	0.914	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.086	0.914	0.000
D81.9 Combined immunodeficiency, unspecified	0.080	0.920	0.000
D81.8 Other combined immunodeficiencies	0.080	0.920	0.000
D81.7 Major histocompatibility complex class II deficiency	0.080	0.920	0.000
D81.6 Major histocompatibility complex class I deficiency	0.080	0.920	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.080	0.920	0.000
D81.4 Nezelof's syndrome	0.080	0.920	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.080	0.920	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.080	0.920	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.080	0.920	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.080	0.920	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.080	0.920	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.080	0.920	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.080	0.920	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.080	0.920	0.000
D82.2 Immunodeficiency with short-limbed stature	0.080	0.920	0.000
D82.1 Di George's syndrome	0.080	0.920	0.000
D82.0 Wiskott-Aldrich syndrome	0.080	0.920	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.076	0.924	0.000
D89.1 Cryoglobulinaemia	0.073	0.927	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.071	0.928	0.000
D89.3 Immune reconstitution syndrome	0.070	0.930	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.060	0.939	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.049	0.951	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.022	0.978	0.000
J03.9 Acute tonsillitis, unspecified	0.020	0.980	0.000
O20 Haemorrhage in early pregnancy	0.018	0.982	0.000
O20.0 Threatened abortion	0.015	0.985	0.000
O20.8 Other haemorrhage in early pregnancy	0.015	0.985	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.013	0.987	0.000
N03.9 Unspecified	0.013	0.987	0.000
O24 Diabetes mellitus in pregnancy	0.012	0.988	0.000
O22 Venous complications in pregnancy	0.012	0.988	0.000
O23 Infections of genito-urinary tract in pregnancy	0.012	0.988	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.010	0.990	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.010	0.990	0.000
O29 Complications of anaesthesia during pregnancy	0.010	0.990	0.000
O25 Malnutrition in pregnancy	0.010	0.990	0.000
O21 Excessive vomiting in pregnancy	0.010	0.990	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.010	0.990	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.010	0.990	0.000
M77.12 Lateral epicondylitis (Upper arm)	0.000	0.990	0.010
O24.4 Diabetes mellitus arising in pregnancy	0.009	0.991	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.009	0.991	0.000
J03 Acute tonsillitis	0.009	0.991	0.000
O28 Abnormal findings on antenatal screening of mother	0.009	0.991	0.000
O04.9 Complete or unspecified, without complication	0.000	0.991	0.009
O22.4 Haemorrhoids in pregnancy	0.009	0.991	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.009	0.991	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.008	0.991	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.008	0.991	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.008	0.991	0.000
O22.9 Venous complication in pregnancy, unspecified	0.008	0.991	0.000
O22.8 Other venous complications in pregnancy	0.008	0.991	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.008	0.991	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.008	0.991	0.000
O22.1 Genital varices in pregnancy	0.008	0.991	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.008	0.991	0.000
O23.2 Infections of urethra in pregnancy	0.008	0.991	0.000
O23.1 Infections of bladder in pregnancy	0.008	0.991	0.000
O23.0 Infections of kidney in pregnancy	0.008	0.991	0.000
U80.1 Methicillin resistant agent	0.008	0.992	0.000
O21.8 Other vomiting complicating pregnancy	0.008	0.992	0.000
H93.1 Tinnitus	0.008	0.992	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.007	0.993	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.007	0.993	0.000
O29.6 Failed or difficult intubation during pregnancy	0.007	0.993	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.007	0.993	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.007	0.993	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.007	0.993	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.007	0.993	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.007	0.993	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.007	0.993	0.000
O21.2 Late vomiting of pregnancy	0.007	0.993	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.007	0.993	0.000
O23.5 Infections of the genital tract in pregnancy	0.007	0.993	0.000
O21.9 Vomiting of pregnancy, unspecified	0.007	0.993	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.007	0.993	0.000
H00.1 Chalazion	0.000	0.993	0.007
J03.8 Acute tonsillitis due to other specified organisms	0.007	0.993	0.000
J03.0 Streptococcal tonsillitis	0.007	0.993	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.007	0.993	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.007	0.993	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.007	0.993	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.007	0.993	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.007	0.993	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.007	0.993	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.993	0.007
N03 Chronic nephritic syndrome	0.007	0.993	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.006	0.993	0.000
O21.0 Mild hyperemesis gravidarum	0.007	0.993	0.000
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.006	0.994	0.000
O04 Medical abortion	0.000	0.994	0.006
O26.2 Pregnancy care of habitual aborter	0.006	0.994	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.006	0.994	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.994	0.006
D22.5 Melanocytic naevi of trunk	0.000	0.994	0.006
D17.9 Benign lipomatous neoplasm, unspecified	0.000	0.995	0.005
K83.8 Other specified diseases of biliary tract	0.000	0.995	0.005
H93 Other disorders of ear, not elsewhere classified	0.005	0.995	0.000
O26.5 Maternal hypotension syndrome	0.005	0.995	0.000
O26.4 Herpes gestationis	0.005	0.995	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.005	0.995	0.000
O26.1 Low weight gain in pregnancy	0.005	0.995	0.000
O26.0 Excessive weight gain in pregnancy	0.005	0.995	0.000
S06.00 Concussion (without open intracranial wound)	0.005	0.995	0.000
N03.5 Diffuse mesangiocapillary glomerulonephritis	0.005	0.995	0.000
N03.8 Other	0.005	0.995	0.000
N03.7 Diffuse crescentic glomerulonephritis	0.005	0.995	0.000
N03.6 Dense deposit disease	0.005	0.995	0.000
N03.4 Diffuse endocapillary proliferative glomerulonephritis	0.005	0.995	0.000
N03.3 Diffuse mesangial proliferative glomerulonephritis	0.005	0.995	0.000
N03.2 Diffuse membranous glomerulonephritis	0.005	0.995	0.000
N03.1 Focal and segmental glomerular lesions	0.005	0.995	0.000
N03.0 Minor glomerular abnormality	0.005	0.995	0.000
O04.8 Complete or unspecified, with other and unspecified complications	0.000	0.995	0.005
O04.7 Complete or unspecified, complicated by embolism	0.000	0.995	0.005
O04.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.000	0.995	0.005
O04.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.000	0.995	0.005
O04.3 Incomplete, with other and unspecified complications	0.000	0.995	0.005
O04.2 Incomplete, complicated by embolism	0.000	0.995	0.005
O04.0 Incomplete, complicated by genital tract and pelvic infection	0.000	0.995	0.005
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
H93.8 Other specified disorders of ear	0.004	0.996	0.000
H93.9 Disorder of ear, unspecified	0.004	0.996	0.000
M77.1 Lateral epicondylitis	0.000	0.996	0.004
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.996	0.004
H93.0 Degenerative and vascular disorders of ear	0.004	0.996	0.000
H93.2 Other abnormal auditory perceptions	0.004	0.996	0.000
E89.0 Postprocedural hypothyroidism	0.004	0.996	0.000
H00 Hordeolum and chalazion	0.000	0.996	0.004
H61.2 Impacted cerumen	0.000	0.996	0.004
M22.8 Other disorders of patella	0.004	0.996	0.000
I51.7 Cardiomegaly	0.004	0.996	0.000
O04.4 Incomplete, without complication	0.000	0.996	0.003
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.003
K41 Femoral hernia	0.000	0.997	0.003
D41.0 Kidney	0.000	0.997	0.003
M77.19 Lateral epicondylitis (Site unspecified)	0.000	0.997	0.003
M77.18 Lateral epicondylitis-Other	0.000	0.997	0.003
M77.17 Lateral epicondylitis-Ankle/Foot	0.000	0.997	0.003
M77.16 Lateral epicondylitis (Lower leg)	0.000	0.997	0.003
M77.15 Lateral epicondylitis (Pelvic region and thigh)	0.000	0.997	0.003
M77.14 Lateral epicondylitis-Hand	0.000	0.997	0.003
M77.11 Lateral epicondylitis-Shldr region	0.000	0.997	0.003
M77.10 Lateral epicondylitis (Multiple sites)	0.000	0.997	0.003
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
C50.3 Lower-inner quadrant of breast	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.000	0.997	0.003
H00.0 Hordeolum and other deep inflammation of eyelid	0.000	0.997	0.003
M77.13 Lateral epicondylitis-Forearm	0.000	0.997	0.003
H81.9 Disorder of vestibular function, unspecified	0.003	0.997	0.000
E89.2 Postprocedural hypoparathyroidism	0.003	0.997	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.997	0.003
M22 Disorders of patella	0.003	0.997	0.000
U80 Agent resistant to penicillin and related antibiotics	0.003	0.997	0.000
K80.2 Calculus of gallbladder without cholecystitis	0.003	0.997	0.000
S06.0 Concussion	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.003	0.997	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.003	0.997	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.003	0.997	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.997	0.003
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.997	0.003
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.997	0.003
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
M22.2 Patellofemoral disorders	0.003	0.997	0.000
H81.3 Other peripheral vertigo	0.003	0.997	0.000
H81 Disorders of vestibular function	0.003	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.002	0.997	0.000
R25.3 Fasciculation	0.000	0.997	0.003
M22.0 Recurrent dislocation of patella	0.002	0.997	0.000
M22.9 Disorder of patella, unspecified	0.002	0.998	0.000
Z34.9 Supervision of normal pregnancy, unspecified	0.002	0.998	0.000
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.998	0.002
H81.2 Vestibular neuronitis	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.998	0.002
M22.3 Other derangements of patella	0.002	0.998	0.000
M22.1 Recurrent subluxation of patella	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.002	0.998	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.002	0.998	0.000
R25 Abnormal involuntary movements	0.000	0.998	0.002
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.002	0.998	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.002	0.998	0.000
E89.5 Postprocedural testicular hypofunction	0.002	0.998	0.000
E89.1 Postprocedural hypoinsulinaemia	0.002	0.998	0.000
J95.0 Tracheostomy malfunction	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
C74.9 Adrenal gland, unspecified	0.002	0.998	0.000
E89.4 Postprocedural ovarian failure	0.002	0.998	0.000
R25.1 Tremor, unspecified	0.000	0.998	0.002
H81.4 Vertigo of central origin	0.002	0.998	0.000
H81.8 Other disorders of vestibular function	0.002	0.998	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.998	0.002
Z94.7 Corneal transplant status	0.002	0.998	0.000
L71.9 Rosacea, unspecified	0.002	0.998	0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.998	0.000
J05.1 Acute epiglottitis	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.002	0.998	0.000
C74 Malignant neoplasm of adrenal gland	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.002	0.998	0.000
D12.3 Transverse colon	0.000	0.998	0.002
R25.0 Abnormal head movements	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
C74.0 Cortex of adrenal gland	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
G82 Paraplegia and tetraplegia	0.000	0.998	0.002
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
H01.0 Blepharitis	0.000	0.998	0.002
L84 Corns and callosities	0.002	0.998	0.000
C74.1 Medulla of adrenal gland	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
W21.9 Unspecified place	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
I11 Hypertensive heart disease	0.000	0.998	0.002
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.002	0.998	0.000
I84.0 Internal thrombosed haemorrhoids	0.000	0.998	0.002
O71.4 Obstetric high vaginal laceration alone	0.002	0.998	0.000
Y43.3 Other antineoplastic drugs	0.002	0.998	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.998	0.002
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.000	0.998	0.002
N00-N08 Glomerular diseases	0.002	0.998	0.000
D57 Sickle-cell disorders	0.002	0.998	0.000
D56 Thalassaemia	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
Y43 Primarily systemic agents	0.002	0.998	0.000
C49.4 Connective and soft tissue of abdomen	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
D55 Anaemia due to enzyme disorders	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.002	0.998	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.002	0.998	0.000
G45.4 Transient global amnesia	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.000	0.998	0.001
G82.0 Flaccid paraplegia	0.000	0.998	0.001
K83.0 Cholangitis	0.000	0.998	0.002
N08.5 Glomerular disorders in systemic connective tissue disorders	0.002	0.998	0.000
D56.1 Beta thalassaemia	0.001	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
C45.7 Mesothelioma of other sites	0.000	0.998	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.001	0.998	0.000
E89.3 Postprocedural hypopituitarism	0.001	0.998	0.000
Z82.3 Family history of stroke	0.000	0.998	0.002
C49.6 Connective and soft tissue of trunk, unspecified	0.001	0.998	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.002	0.998	0.000
Z74.1 Need for assistance with personal care	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.000	0.998	0.002
D41.9 Urinary organ, unspecified	0.000	0.998	0.001
D41.7 Other urinary organs	0.000	0.998	0.001
D41.3 Urethra	0.000	0.998	0.001
D41.1 Renal pelvis	0.000	0.998	0.001
S00.0 Superficial injury of scalp	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.001	0.998	0.000
D59 Acquired haemolytic anaemia	0.001	0.998	0.000
D57.1 Sickle-cell anaemia without crisis	0.001	0.998	0.000
C73 Malignant neoplasm of thyroid gland	0.002	0.998	0.000
N00 Acute nephritic syndrome	0.001	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.002	0.998	0.000
D56.9 Thalassaemia, unspecified	0.001	0.998	0.000
D56.8 Other thalassaemias	0.001	0.998	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.001	0.998	0.000
D56.2 Delta-beta thalassaemia	0.001	0.998	0.000
D56.0 Alpha thalassaemia	0.001	0.998	0.000
D57.8 Other sickle-cell disorders	0.001	0.998	0.000
D57.3 Sickle-cell trait	0.001	0.998	0.000
D57.2 Double heterozygous sickling disorders	0.001	0.998	0.000
D57.0 Sickle-cell anaemia with crisis	0.001	0.998	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.001	0.998	0.000
N06 Isolated proteinuria with specified morphological lesion	0.001	0.998	0.000
N01 Rapidly progressive nephritic syndrome	0.001	0.998	0.000
D58.2 Other haemoglobinopathies	0.001	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.001
Y43.9 Primarily systemic agent, unspecified	0.001	0.998	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.001	0.998	0.000
Y43.6 Enzymes, not elsewhere classified	0.001	0.998	0.000
Y43.5 Acidifying and alkalising agents	0.001	0.998	0.000
Y43.2 Antineoplastic natural products	0.001	0.998	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.001	0.998	0.000
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.001	0.999	0.000
D55.8 Other anaemias due to enzyme disorders	0.001	0.999	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.001	0.999	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.001	0.999	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.001	0.999	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.001	0.999	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.001	0.999	0.000
D58.1 Hereditary elliptocytosis	0.001	0.999	0.000
C45.0 Mesothelioma of pleura	0.000	0.999	0.001
D58.9 Hereditary haemolytic anaemia, unspecified	0.001	0.999	0.000
W01.1 Residential institution	0.001	0.999	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.001	0.999	0.000
D56.3 Thalassaemia trait	0.001	0.999	0.000
C45 Mesothelioma	0.000	0.999	0.001
I51.0 Cardiac septal defect, acquired	0.001	0.999	0.000
M54.6 Pain in thoracic spine	0.000	0.999	0.001
N00.9 Unspecified	0.001	0.999	0.000
N04.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N95.9 Menopausal and perimenopausal disorder, unspecified	0.001	0.999	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.001	0.999	0.000
I51.6 Cardiovascular disease, unspecified	0.001	0.999	0.000
K06.1 Gingival enlargement	0.001	0.999	0.000
K83.5 Biliary cyst	0.000	0.999	0.001
K83.4 Spasm of sphincter of Oddi	0.000	0.999	0.001
K83.2 Perforation of bile duct	0.000	0.999	0.001
Y43.4 Immunosuppressive agents	0.001	0.999	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.001	0.999	0.000
D41.2 Ureter	0.000	0.999	0.001
D59.8 Other acquired haemolytic anaemias	0.001	0.999	0.000
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.001	0.999	0.000
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.001	0.999	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.001	0.999	0.000
D59.3 Haemolytic-uraemic syndrome	0.001	0.999	0.000
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.001	0.999	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.001	0.999	0.000
D76.3 Other histiocytosis syndromes	0.000	0.999	0.001
N00.8 Other	0.001	0.999	0.000
N00.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N00.6 Dense deposit disease	0.001	0.999	0.000
N00.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N00.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N00.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N00.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N00.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N00.0 Minor glomerular abnormality	0.001	0.999	0.000
Y83.9 Surgical procedure, unspecified	0.000	0.999	0.001
Z74.8 Other problems related to care-provider dependency	0.001	0.999	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.001	0.999	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.999	0.001
D58.0 Hereditary spherocytosis	0.001	0.999	0.000
K63.1 Perforation of intestine (nontraumatic)	0.001	0.999	0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.999	0.001
N04 Nephrotic syndrome	0.001	0.999	0.000
I51.3 Intracardiac thrombosis, not elsewhere classified	0.001	0.999	0.000
J05.0 Acute obstructive laryngitis [croup]	0.001	0.999	0.000
K26.3 Acute without haemorrhage or perforation	0.001	0.999	0.000
N01.9 Unspecified	0.001	0.999	0.000
N01.8 Other	0.001	0.999	0.000
N01.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N01.6 Dense deposit disease	0.001	0.999	0.000
N01.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N01.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N01.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N01.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N01.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N01.0 Minor glomerular abnormality	0.001	0.999	0.000
N06.9 Unspecified	0.001	0.999	0.000
N06.8 Other	0.001	0.999	0.000
N06.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N06.6 Dense deposit disease	0.001	0.999	0.000
N06.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N06.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N06.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N06.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N06.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N06.0 Minor glomerular abnormality	0.001	0.999	0.000
N07.9 Unspecified	0.001	0.999	0.000
N07.8 Other	0.001	0.999	0.000
N07.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N07.6 Dense deposit disease	0.001	0.999	0.000
N07.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N07.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N07.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N07.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
N07.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
N07.0 Minor glomerular abnormality	0.001	0.999	0.000
Z22.5 Carrier of viral hepatitis	0.001	0.999	0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.001	0.999	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.001	0.999	0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.001	0.999	0.000
I51 Complications and ill-defined descriptions of heart disease	0.001	0.999	0.000
K83.3 Fistula of bile duct	0.000	0.999	0.001
S62.40 Multiple fractures of metacarpal bones (closed)	0.001	0.999	0.000
C45.2 Mesothelioma of pericardium	0.000	0.999	0.001
C45.1 Mesothelioma of peritoneum	0.000	0.999	0.001
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.001	0.999	0.000
N02.1 Focal and segmental glomerular lesions	0.001	0.999	0.000
R82.9 Other and unspecified abnormal finding in urine	0.000	0.999	0.001
M54.69 Pain in thoracic spine-Site unspe	0.000	0.999	0.001
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.000	0.999	0.001
M54.67 Pain in thoracic spine-Lumbosacral	0.000	0.999	0.001
M54.66 Pain in thoracic spine-Lumbar	0.000	0.999	0.001
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.000	0.999	0.001
M54.62 Pain in thoracic spine-Cervical	0.000	0.999	0.001
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.000	0.999	0.001
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.000	0.999	0.001
G82.4 Spastic tetraplegia	0.000	0.999	0.001
J95.8 Other postprocedural respiratory disorders	0.000	0.999	0.001
N08.8 Glomerular disorders in other diseases classified elsewhere	0.001	0.999	0.000
N08.4 Glomerular disorders in other endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
N08.2 Glomerular disorders in blood diseases and disorders involving the immune mechanism	0.001	0.999	0.000
N08.1 Glomerular disorders in neoplastic diseases	0.001	0.999	0.000
N08.0 Glomerular disorders in infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
W29.9 Unspecified place	0.001	0.999	0.000
K06.0 Gingival recession	0.001	0.999	0.000
Y84.2 Radiological procedure and radiotherapy	0.001	0.999	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.999	0.000
C91.0 Acute lymphoblastic leukaemia	0.001	0.999	0.000
D59.1 Other autoimmune haemolytic anaemias	0.001	0.999	0.000
G30.1 Alzheimer's disease with late onset	0.001	0.999	0.000
J95 Postprocedural respiratory disorders, not elsewhere classified	0.000	0.999	0.001
U81 Agent resistant to vancomycin and related antibiotics	0.001	0.999	0.000
H50.9 Strabismus, unspecified	0.000	0.999	0.001
H65.4 Other chronic nonsuppurative otitis media	0.001	0.999	0.000
K83.9 Disease of biliary tract, unspecified	0.000	0.999	0.001
M21.2 Flexion deformity	0.001	0.999	0.000
N04.8 Other	0.001	0.999	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.001	0.999	0.000
N04.6 Dense deposit disease	0.001	0.999	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.001	0.999	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.001	0.999	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.001	0.999	0.000
N04.0 Minor glomerular abnormality	0.001	0.999	0.000
N05.8 Other	0.001	0.999	0.000
R16.1 Splenomegaly, not elsewhere classified	0.000	0.999	0.001
Z74.2 Need for assistance at home and no other household member able to render care	0.001	0.999	0.000
U50 Level of care administered to neonates	0.001	0.999	0.000
U07 Emergency use of U07	0.001	0.999	0.000
U06 Emergency use of U06	0.001	0.999	0.000
U04 Severe acute respiratory syndrome [SARS]	0.001	0.999	0.000
U52 First in a series of a regular day/night admissions	0.001	0.999	0.000
H80-H83 Diseases of inner ear	0.001	0.999	0.000
C91.9 Lymphoid leukaemia, unspecified	0.001	0.999	0.000
D61.9 Aplastic anaemia, unspecified	0.001	0.999	0.000
I51.5 Myocardial degeneration	0.001	0.999	0.000
I51.2 Rupture of papillary muscle, not elsewhere classified	0.001	0.999	0.000
O71.5 Other obstetric injury to pelvic organs	0.001	0.999	0.000
M21.26 Flexion deformity (Lower leg)	0.001	0.999	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.001	0.999	0.000
G30.8 Other Alzheimer's disease	0.001	0.999	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.001	0.999	0.000
T18.1 Foreign body in oesophagus	0.001	0.999	0.000
C91.5 Adult T-cell leukaemia	0.001	0.999	0.000
N04.2 Diffuse membranous glomerulonephritis	0.001	0.999	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.001	0.999	0.000
F05.1 Delirium superimposed on dementia	0.001	0.999	0.000
J95.5 Postprocedural subglottic stenosis	0.000	0.999	0.001
J95.4 Mendelson's syndrome	0.000	0.999	0.001
J95.3 Chronic pulmonary insufficiency following surgery	0.000	0.999	0.001
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.000	0.999	0.001
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.000	0.999	0.001
U81.8 Agent resistant to other vancomycin-related antibiotic	0.001	0.999	0.000
U81.0 Vancomycin resistant agent	0.001	0.999	0.000
Y41.1 Antimycobacterial drugs	0.001	0.999	0.000
N05 Unspecified nephritic syndrome	0.001	0.999	0.000
N02 Recurrent and persistent haematuria	0.001	0.999	0.000
M21.29 Flexion deformity (Site unspecified)	0.001	0.999	0.000
M21.28 Flexion deformity (Other)	0.001	0.999	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.999	0.000
M21.23 Flexion deformity (Forearm)	0.001	0.999	0.000
M21.22 Flexion deformity (Upper arm)	0.001	0.999	0.000
M21.21 Flexion deformity (Shoulder region)	0.001	0.999	0.000
M21.20 Flexion deformity (Multiple sites)	0.001	0.999	0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.000	0.999	0.001
G30.0 Alzheimer's disease with early onset	0.001	0.999	0.000
R09.1 Pleurisy	0.000	0.999	0.001
U04.9 Severe acute respiratory syndrome [SARS], unspecified	0.001	0.999	0.000
U06.9 Emergency use of U06.9	0.001	0.999	0.000
U06.8 Emergency use of U06.8	0.001	0.999	0.000
U06.7 Emergency use of U06.7	0.001	0.999	0.000
U06.6 Emergency use of U06.6	0.001	0.999	0.000
U06.5 Emergency use of U06.5	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations