TreeWAS – Variant ID: rs11695685

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70 Alcoholic liver disease	0.242	0.758	0.000
K70-K77 Diseases of liver	0.240	0.760	0.000
K76.8 Other specified diseases of liver	0.231	0.769	0.000
K76 Other diseases of liver	0.230	0.770	0.000
K70.0 Alcoholic fatty liver	0.228	0.772	0.000
K73 Chronic hepatitis, not elsewhere classified	0.226	0.774	0.000
K70.9 Alcoholic liver disease, unspecified	0.226	0.774	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.212	0.788	0.000
K70.4 Alcoholic hepatic failure	0.207	0.793	0.000
K70.3 Alcoholic cirrhosis of liver	0.206	0.794	0.000
K74 Fibrosis and cirrhosis of liver	0.202	0.798	0.000
K72 Hepatic failure, not elsewhere classified	0.192	0.808	0.000
K73.9 Chronic hepatitis, unspecified	0.192	0.808	0.000
K76.7 Hepatorenal syndrome	0.181	0.819	0.000
K76.6 Portal hypertension	0.180	0.820	0.000
K77 Liver disorders in diseases classified elsewhere	0.172	0.828	0.000
K71 Toxic liver disease	0.171	0.829	0.000
K74.6 Other and unspecified cirrhosis of liver	0.169	0.831	0.000
K74.1 Hepatic sclerosis	0.168	0.832	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.165	0.834	0.000
K76.5 Hepatic veno-occlusive disease	0.165	0.835	0.000
K76.4 Peliosis hepatis	0.165	0.835	0.000
K76.3 Infarction of liver	0.165	0.835	0.000
K76.2 Central haemorrhagic necrosis of liver	0.165	0.835	0.000
K75 Other inflammatory liver diseases	0.165	0.835	0.000
K74.0 Hepatic fibrosis	0.164	0.836	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.162	0.838	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.162	0.838	0.000
K72.0 Acute and subacute hepatic failure	0.162	0.838	0.000
K76.1 Chronic passive congestion of liver	0.160	0.840	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.150	0.850	0.000
K74.4 Secondary biliary cirrhosis	0.145	0.855	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.145	0.855	0.000
K72.1 Chronic hepatic failure	0.144	0.856	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.142	0.858	0.000
K74.5 Biliary cirrhosis, unspecified	0.142	0.858	0.000
K70.1 Alcoholic hepatitis	0.139	0.861	0.000
K75.8 Other specified inflammatory liver diseases	0.136	0.864	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.129	0.870	0.000
K75.9 Inflammatory liver disease, unspecified	0.129	0.871	0.000
K72.9 Hepatic failure, unspecified	0.124	0.876	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.123	0.876	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.123	0.876	0.000
K71.9 Toxic liver disease, unspecified	0.122	0.877	0.000
K71.8 Toxic liver disease with other disorders of liver	0.122	0.877	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.122	0.877	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.122	0.877	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.122	0.877	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.122	0.877	0.000
K71.2 Toxic liver disease with acute hepatitis	0.122	0.877	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.121	0.879	0.000
K75.2 Nonspecific reactive hepatitis	0.119	0.881	0.000
K75.1 Phlebitis of portal vein	0.119	0.881	0.000
K71.0 Toxic liver disease with cholestasis	0.115	0.885	0.000
K75.4 Autoimmune hepatitis	0.114	0.886	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.113	0.887	0.000
K74.3 Primary biliary cirrhosis	0.092	0.908	0.000
K75.0 Abscess of liver	0.079	0.921	0.000
K11.2 Sialoadenitis	0.000	0.945	0.055
K11.9 Disease of salivary gland, unspecified	0.000	0.957	0.043
K11 Diseases of salivary glands	0.000	0.958	0.042
K11.8 Other diseases of salivary glands	0.000	0.964	0.036
K11.4 Fistula of salivary gland	0.000	0.970	0.030
K11.0 Atrophy of salivary gland	0.000	0.970	0.030
N28.8 Other specified disorders of kidney and ureter	0.000	0.970	0.030
K11.1 Hypertrophy of salivary gland	0.000	0.971	0.029
K76.9 Liver disease, unspecified	0.028	0.972	0.000
K11.6 Mucocele of salivary gland	0.000	0.974	0.026
K11.7 Disturbances of salivary secretion	0.000	0.975	0.025
K11.3 Abscess of salivary gland	0.000	0.977	0.023
K11.5 Sialolithiasis	0.000	0.979	0.021
W22.9 Unspecified place	0.020	0.980	0.000
Z86.6 Personal history of diseases of the nervous system and sense organs	0.000	0.985	0.015
Z99.3 Dependence on wheelchair	0.007	0.993	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.007	0.993	0.000
W22 Striking against or struck by other objects	0.007	0.993	0.000
N42.1 Congestion and haemorrhage of prostate	0.000	0.993	0.007
W22.5 Trade and service area	0.006	0.994	0.000
I12.0 Hypertensive renal disease with renal failure	0.006	0.994	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.005	0.995	0.000
W22.8 Other specified place	0.005	0.995	0.000
W22.6 Industrial and construction area	0.005	0.995	0.000
W22.4 Street and highway	0.005	0.995	0.000
W22.0 Home	0.005	0.995	0.000
W22.7 Farm	0.005	0.995	0.000
W22.1 Residential institution	0.005	0.995	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.005	0.995	0.000
G37 Other demyelinating diseases of central nervous system	0.005	0.995	0.000
N60.4 Mammary duct ectasia	0.004	0.996	0.000
K86.9 Disease of pancreas, unspecified	0.004	0.996	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.004	0.996	0.000
W22.3 Sports and athletics area	0.004	0.996	0.000
I45.6 Preexcitation syndrome	0.004	0.996	0.000
C34.3 Lower lobe, bronchus or lung	0.004	0.996	0.000
D68.0 Von Willebrand's disease	0.004	0.996	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.996	0.004
W22.2 School, other institution and public administrative area	0.004	0.996	0.000
K25.4 Chronic or unspecified with haemorrhage	0.000	0.996	0.004
G37.8 Other specified demyelinating diseases of central nervous system	0.004	0.996	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.996	0.004
N42.8 Other specified disorders of prostate	0.000	0.996	0.004
W22.09 Striking against or struck by other objects; Home; During unspecified activity	0.004	0.996	0.000
W22.03 Striking against or struck by other objects; Home; While engaged in other types of work	0.004	0.996	0.000
W22.41 Striking against or struck by other objects; Street and highway;While engaged in leisure activity	0.004	0.996	0.000
W22.62 Striking against or struck by other objects; Industrial and construction area ;While working for income	0.004	0.996	0.000
W22.88 Striking against or struck by other objects; Other specified places ;While engaged in other specified activities	0.004	0.996	0.000
D12.0 Caecum	0.004	0.996	0.000
N42 Other disorders of prostate	0.000	0.996	0.004
D22.1 Melanocytic naevi of eyelid, including canthus	0.000	0.996	0.004
H54.9 Unspecified visual impairment (binocular)	0.004	0.996	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.996	0.000
G37.4 Subacute necrotising myelitis	0.003	0.996	0.000
G37.2 Central pontine myelinolysis	0.003	0.996	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.996	0.000
G37.0 Diffuse sclerosis	0.003	0.996	0.000
N42.9 Disorder of prostate, unspecified	0.000	0.996	0.004
G35 Multiple sclerosis	0.003	0.997	0.000
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
I77.9 Disorder of arteries and arterioles, unspecified	0.003	0.997	0.000
D68.2 Hereditary deficiency of other clotting factors	0.003	0.997	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.003	0.997	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
Q07.0 Arnold-Chiari syndrome	0.003	0.997	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
C34.1 Upper lobe, bronchus or lung	0.003	0.997	0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
N42.3 Dysplasia of prostate	0.000	0.997	0.003
N42.2 Atrophy of prostate	0.000	0.997	0.003
T47.1 Other antacids and anti-gastric-secretion drugs	0.003	0.997	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.003	0.997	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.003	0.997	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.003	0.997	0.000
T51.0 Ethanol	0.003	0.997	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.003	0.997	0.000
Z99.2 Dependence on renal dialysis	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.997	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
G36 Other acute disseminated demyelination	0.002	0.998	0.000
Z89.4 Acquired absence of foot and ankle	0.000	0.998	0.002
Z64.0 Problems related to unwanted pregnancy	0.000	0.998	0.002
C18.9 Colon, unspecified	0.002	0.998	0.000
S82.3 Fracture of lower end of tibia	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
D68 Other coagulation defects	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.998	0.002
F22.0 Delusional disorder	0.002	0.998	0.000
C34 Malignant neoplasm of bronchus and lung	0.002	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.002	0.998	0.000
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
F32.1 Moderate depressive episode	0.000	0.998	0.002
Q07 Other congenital malformations of nervous system	0.002	0.998	0.000
J36 Peritonsillar abscess	0.000	0.998	0.002
C80.9 Malignant neoplasm, unspecified	0.000	0.998	0.002
H33.0 Retinal detachment with retinal break	0.000	0.998	0.002
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
Z12.8 Special screening examination for neoplasm of other sites	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
G36.9 Acute disseminated demyelination, unspecified	0.002	0.998	0.000
G36.8 Other specified acute disseminated demyelination	0.002	0.998	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.002	0.998	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.002	0.998	0.000
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.002	0.998	0.000
F32.0 Mild depressive episode	0.000	0.998	0.002
J98.4 Other disorders of lung	0.000	0.998	0.002
Q07.8 Other specified congenital malformations of nervous system	0.002	0.998	0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.002	0.998	0.000
G36.0 Neuromyelitis optica [Devic]	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.002	0.998	0.000
H54.2 Low vision, both eyes	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.002	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.002	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.002	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.002	0.998	0.000
O23.0 Infections of kidney in pregnancy	0.002	0.998	0.000
H54 Blindness and low vision	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.002
H33.5 Other retinal detachments	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.000	0.998	0.002
Q07.9 Congenital malformation of nervous system, unspecified	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.000	0.998	0.002
N42.0 Calculus of prostate	0.000	0.998	0.001
I85.0 Oesophageal varices with bleeding	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
C34.8 Overlapping lesion of bronchus and lung	0.002	0.998	0.000
C57.0 Fallopian tube	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.998	0.002
Q60.3 Renal hypoplasia, unilateral	0.002	0.998	0.000
C34.0 Main bronchus	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
Q60.6 Potter's syndrome	0.002	0.998	0.000
Q60.5 Renal hypoplasia, unspecified	0.002	0.998	0.000
Q60.4 Renal hypoplasia, bilateral	0.002	0.998	0.000
Q60.1 Renal agenesis, bilateral	0.002	0.998	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.002	0.998	0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.000	0.998	0.002
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.000	0.998	0.002
H54.1 Blindness, one eye, low vision, other eye	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
Z99.9 Dependence on unspecified enabling machine and device	0.002	0.998	0.000
Z99.4 Dependence on artificial heart	0.002	0.998	0.000
Z99.0 Dependence on aspirator	0.002	0.998	0.000
C34.2 Middle lobe, bronchus or lung	0.002	0.998	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.002	0.998	0.000
R06.2 Wheezing	0.002	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.002	0.998	0.000
H54.3 Unqualified visual loss, both eyes	0.002	0.998	0.000
M21.3 Wrist or foot drop (acquired)	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.998	0.000
H27.0 Aphakia	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.002	0.998	0.000
K83.0 Cholangitis	0.002	0.998	0.000
L93.0 Discoid lupus erythematosus	0.000	0.998	0.002
N73.9 Female pelvic inflammatory disease, unspecified	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.998	0.000
V18.0 Driver injured in nontraffic accident	0.002	0.998	0.000
V19.3 Pedal cyclist [any] injured in an unspecified nontraffic accident	0.002	0.998	0.000
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
F20.0 Paranoid schizophrenia	0.000	0.998	0.002
H54.5 Low vision, one eye	0.001	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.998	0.001
T45.5 Anticoagulants	0.001	0.998	0.000
Y57.8 Other drugs and medicaments	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
Y57.5 X-ray contrast media	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.001	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.001	0.998	0.000
T78.3 Angioneurotic oedema	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
D17.7 Benign lipomatous neoplasm of other sites	0.001	0.999	0.000
K25.0 Acute with haemorrhage	0.000	0.999	0.001
T36.0 Penicillins	0.001	0.999	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.001	0.999	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.001	0.999	0.000
G54.9 Nerve root and plexus disorder, unspecified	0.001	0.999	0.000
H33.3 Retinal breaks without detachment	0.000	0.999	0.001
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.999	0.001
M21.39 Wrist or foot drop (acquired)-Site unspec	0.001	0.999	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.001	0.999	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.001	0.999	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.001	0.999	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.001	0.999	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.001	0.999	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.001	0.999	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.001	0.999	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.001	0.999	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.001	0.999	0.000
Y45.0 Opioids and related analgesics	0.001	0.999	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.001	0.999	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.999	0.001
H54.6 Unqualified visual loss, one eye	0.001	0.999	0.000
K14.0 Glossitis	0.001	0.999	0.000
M47.2 Other spondylosis with radiculopathy	0.001	0.999	0.000
T50.8 Diagnostic agents	0.001	0.999	0.000
T50.4 Drugs affecting uric acid metabolism	0.001	0.999	0.000
N25.8 Other disorders resulting from impaired renal tubular function	0.001	0.999	0.000
W50.9 Unspecified place	0.000	0.999	0.001
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.999	0.001
E83.1 Disorders of iron metabolism	0.001	0.999	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.999	0.001
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.999	0.001
T43.5 Other and unspecified antipsychotics and neuroleptics	0.001	0.999	0.000
M79.83 Other specified soft tissue disorders (Forearm)	0.000	0.999	0.001
H54.0 Blindness, both eyes	0.001	0.999	0.000
K43.0 Ventral hernia with obstruction, without gangrene	0.000	0.999	0.001
T36.3 Macrolides	0.001	0.999	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.001	0.999	0.000
T45.8 Other primarily systemic and haematological agents	0.001	0.999	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.001	0.999	0.000
T45.6 Fibrinolysis-affecting drugs	0.001	0.999	0.000
T45.4 Iron and its compounds	0.001	0.999	0.000
T45.3 Enzymes, not elsewhere classified	0.001	0.999	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.001	0.999	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.001	0.999	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.001	0.999	0.000
N84.2 Polyp of vagina	0.001	0.999	0.000
T36.9 Systemic antibiotic, unspecified	0.001	0.999	0.000
T36.8 Other systemic antibiotics	0.001	0.999	0.000
T36.7 Antifungal antibiotics, systemically used	0.001	0.999	0.000
T36.6 Rifamycins	0.001	0.999	0.000
T36.5 Aminoglycosides	0.001	0.999	0.000
T36.4 Tetracyclines	0.001	0.999	0.000
T36.2 Chloramphenicol group	0.001	0.999	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.001	0.999	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.999	0.001
C57.8 Overlapping lesion of female genital organs	0.001	0.999	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.999	0.001
F32.8 Other depressive episodes	0.000	0.999	0.001
H54.4 Blindness, one eye	0.001	0.999	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
M96.8 Other postprocedural musculoskeletal disorders	0.001	0.999	0.000
T49.9 Topical agent, unspecified	0.001	0.999	0.000
T49.8 Other topical agents	0.001	0.999	0.000
T49.7 Dental drugs, topically applied	0.001	0.999	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.001	0.999	0.000
T49.5 Ophthalmological drugs and preparations	0.001	0.999	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.001	0.999	0.000
T49.3 Emollients, demulcents and protectants	0.001	0.999	0.000
T49.2 Local astringents and local detergents	0.001	0.999	0.000
T49.1 Antipruritics	0.001	0.999	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.001	0.999	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.001	0.999	0.000
V18 Pedal cyclist injured in noncollision transport accident	0.001	0.999	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.999	0.001
N18.2 Chronic kidney disease, stage 2	0.001	0.999	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.001	0.999	0.000
T50.7 Analeptics and opioid receptor antagonists	0.001	0.999	0.000
T50.5 Appetite depressants	0.001	0.999	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.001	0.999	0.000
T50.1 Loop [high-ceiling] diuretics	0.001	0.999	0.000
T50.0 Mineralocorticoids and their antagonists	0.001	0.999	0.000
V18.3 Person injured while boarding or alighting	0.001	0.999	0.000
I38 Endocarditis, valve unspecified	0.001	0.999	0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)	0.001	0.999	0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)	0.001	0.999	0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)	0.001	0.999	0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)	0.001	0.999	0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)	0.001	0.999	0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)	0.001	0.999	0.000
G44.0 Cluster headache syndrome	0.001	0.999	0.000
G54.2 Cervical root disorders, not elsewhere classified	0.001	0.999	0.000
F32 Depressive episode	0.000	0.999	0.001
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.999	0.001
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.999	0.001
T50.6 Antidotes and chelating agents, not elsewhere classified	0.001	0.999	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.001	0.999	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.001	0.999	0.000
U88 Agent resistant to multiple antibiotics	0.001	0.999	0.000
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.001	0.999	0.000
G54.1 Lumbosacral plexus disorders	0.001	0.999	0.000
H10.9 Conjunctivitis, unspecified	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
M21.0 Valgus deformity, not elsewhere classified	0.001	0.999	0.000
T43.9 Psychotropic drug, unspecified	0.001	0.999	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.001	0.999	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.001	0.999	0.000
T45.2 Vitamins, not elsewhere classified	0.001	0.999	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.001	0.999	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.001	0.999	0.000
X09.0 Home	0.001	0.999	0.000
H74 Other disorders of middle ear and mastoid	0.000	0.999	0.001
K86 Other diseases of pancreas	0.001	0.999	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.999	0.001
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.000	0.999	0.001
N64.4 Mastodynia	0.001	0.999	0.000
S46.2 Injury of muscle and tendon of other parts of biceps	0.000	0.999	0.001
T41.5 Therapeutic gases	0.001	0.999	0.000
T41.4 Anaesthetic, unspecified	0.001	0.999	0.000
T41.3 Local anaesthetics	0.001	0.999	0.000
T41.2 Other and unspecified general anaesthetics	0.001	0.999	0.000
T41.1 Intravenous anaesthetics	0.001	0.999	0.000
T41.0 Inhaled anaesthetics	0.001	0.999	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.001	0.999	0.000
C52 Malignant neoplasm of vagina	0.001	0.999	0.000
C80 Malignant neoplasm without specification of site	0.000	0.999	0.001
M47.26 Other spondylosis with radiculopathy (Lumbar region)	0.001	0.999	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.999	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.999	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.999	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.999	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.999	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.999	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.999	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.999	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
C57.7 Other specified female genital organs	0.001	0.999	0.000
C57.4 Uterine adnexa, unspecified	0.001	0.999	0.000
C57.3 Parametrium	0.001	0.999	0.000
C57.2 Round ligament	0.001	0.999	0.000
C57.1 Broad ligament	0.001	0.999	0.000
H69.8 Other specified disorders of Eustachian tube	0.001	0.999	0.000
K65.0 Acute peritonitis	0.001	0.999	0.000
V18.5 Passenger injured in traffic accident	0.001	0.999	0.000
K25 Gastric ulcer	0.000	0.999	0.001
K85.9 Acute pancreatitis, unspecified	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.001	0.999	0.000
T43.6 Psychostimulants with abuse potential	0.001	0.999	0.000
V18.9 Unspecified pedal cyclist injured in traffic accident	0.001	0.999	0.000
V18.4 Driver injured in traffic accident	0.001	0.999	0.000
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
C54.9 Corpus uteri, unspecified	0.001	0.999	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.001	0.999	0.000
J46 Status asthmaticus	0.000	0.999	0.001
M48.00 Spinal stenosis (Multiple sites in spine)	0.000	0.999	0.001
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.999	0.001
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.999	0.001
R45.8 Other symptoms and signs involving emotional state	0.001	0.999	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.999	0.000
T37.5 Antiviral drugs	0.001	0.999	0.000
T37.4 Anthelminthics	0.001	0.999	0.000
T37.3 Other antiprotozoal drugs	0.001	0.999	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.001	0.999	0.000
T37.1 Antimycobacterial drugs	0.001	0.999	0.000
T37.0 Sulphonamides	0.001	0.999	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.999	0.000
T48.5 Anti-common-cold drugs	0.001	0.999	0.000
T48.4 Expectorants	0.001	0.999	0.000
T48.3 Antitussives	0.001	0.999	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.999	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.999	0.000
T48.0 Oxytocic drugs	0.001	0.999	0.000
Y43.3 Other antineoplastic drugs	0.001	0.999	0.000
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.001	0.999	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.999	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.001	0.999	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.001	0.999	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
E87.7 Fluid overload	0.001	0.999	0.000
K92.8 Other specified diseases of digestive system	0.001	0.999	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.001	0.999	0.000
T46.7 Peripheral vasodilators	0.001	0.999	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.001	0.999	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.999	0.000
M13.89 Other specified arthritis (Site unspecified)	0.001	0.999	0.000
C54.1 Endometrium	0.001	0.999	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.999	0.001
K25.2 Acute with both haemorrhage and perforation	0.000	0.999	0.001
K25.1 Acute with perforation	0.000	0.999	0.001
Q64.4 Malformation of urachus	0.001	0.999	0.000
S81.8 Open wound of other parts of lower leg	0.001	0.999	0.000
V18.1 Passenger injured in nontraffic accident	0.001	0.999	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.999	0.001
S62.70 Multiple fractures of fingers (closed)	0.001	0.999	0.000
V18.49 Pedal cyclist injured in noncollision transport accident; driver injured in traffic accident ; during unspecified activity	0.001	0.999	0.000
V18.99 Pedal cyclist injured in noncollision transport accident; unspecified pedal cyclist injured in traffic accident; during unspecified activity	0.001	0.999	0.000
C57.9 Female genital organ, unspecified	0.001	0.999	0.000
H74.0 Tympanosclerosis	0.000	0.999	0.001
N81.3 Complete uterovaginal prolapse	0.001	0.999	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999	0.000
M25.06 Haemarthrosis (Lower leg)	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.001	0.999	0.000
D68.8 Other specified coagulation defects	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.999	0.001
Q24.8 Other specified congenital malformations of heart	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.000	0.999	0.001
C54 Malignant neoplasm of corpus uteri	0.001	0.999	0.000
Q06 Other congenital malformations of spinal cord	0.001	0.999	0.000
Q01 Encephalocele	0.001	0.999	0.000
Q00 Anencephaly and similar malformations	0.001	0.999	0.000
Q02 Microcephaly	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations