TreeWAS – Variant ID: rs11698080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K63.5 Polyp of colon	0.000	0.000	1.000
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.000	0.000	1.000
D12.5 Sigmoid colon	0.000	0.000	1.000
K62.1 Rectal polyp	0.000	0.001	0.999
D12.4 Descending colon	0.000	0.017	0.983
D12.3 Transverse colon	0.000	0.027	0.973
D12.8 Rectum	0.000	0.030	0.970
D12.6 Colon, unspecified	0.000	0.031	0.969
D12.0 Caecum	0.000	0.034	0.966
D12.7 Rectosigmoid junction	0.000	0.160	0.840
D12.9 Anus and anal canal	0.000	0.162	0.838
K63 Other diseases of intestine	0.000	0.214	0.786
D12.2 Ascending colon	0.000	0.225	0.775
K62 Other diseases of anus and rectum	0.000	0.312	0.688
K55-K64 Other diseases of intestines	0.000	0.323	0.677
K63.9 Disease of intestine, unspecified	0.000	0.326	0.674
K62.9 Disease of anus and rectum, unspecified	0.000	0.370	0.630
K63.3 Ulcer of intestine	0.000	0.379	0.621
K63.8 Other specified diseases of intestine	0.000	0.384	0.616
K62.7 Radiation proctitis	0.000	0.408	0.592
K60 Fissure and fistula of anal and rectal regions	0.000	0.415	0.585
K55 Vascular disorders of intestine	0.000	0.443	0.557
K60.1 Chronic anal fissure	0.000	0.447	0.553
K60.0 Acute anal fissure	0.000	0.463	0.537
K63.1 Perforation of intestine (nontraumatic)	0.000	0.480	0.520
D12.1 Appendix	0.000	0.481	0.519
K63.0 Abscess of intestine	0.000	0.481	0.519
K62.6 Ulcer of anus and rectum	0.000	0.511	0.489
K64 Haemorrhoids and perianal venous thrombosis	0.000	0.514	0.486
K55.9 Vascular disorder of intestine, unspecified	0.000	0.521	0.479
K55.1 Chronic vascular disorders of intestine	0.000	0.521	0.479
K63.4 Enteroptosis	0.000	0.526	0.474
K60.5 Anorectal fistula	0.000	0.551	0.449
K59 Other functional intestinal disorders	0.000	0.555	0.445
K55.0 Acute vascular disorders of intestine	0.000	0.568	0.432
K60.4 Rectal fistula	0.000	0.610	0.390
K59.3 Megacolon, not elsewhere classified	0.000	0.616	0.384
K59.4 Anal spasm	0.000	0.628	0.372
K58 Irritable bowel syndrome	0.000	0.630	0.370
K62.2 Anal prolapse	0.000	0.636	0.364
K64.9 Haemorrhoids, unspecified	0.000	0.651	0.348
K64.8 Other specified haemorrhoids	0.000	0.651	0.348
K64.5 Perianal venous thrombosis	0.000	0.651	0.348
K64.4 Residual haemorrhoidal skin tags	0.000	0.651	0.348
K64.3 Fourth degree haemorrhoids	0.000	0.651	0.348
K64.2 Third degree haemorrhoids	0.000	0.651	0.348
K64.1 Second degree haemorrhoids	0.000	0.651	0.348
K64.0 First degree haemorrhoids	0.000	0.651	0.348
K55.8 Other vascular disorders of intestine	0.000	0.653	0.347
K59.8 Other specified functional intestinal disorders	0.000	0.662	0.338
K59.1 Functional diarrhoea	0.000	0.679	0.321
K62.0 Anal polyp	0.000	0.683	0.317
K59.9 Functional intestinal disorder, unspecified	0.000	0.687	0.313
K58.0 Irritable bowel syndrome with diarrhoea	0.000	0.696	0.304
K62.8 Other specified diseases of anus and rectum	0.000	0.699	0.301
K59.2 Neurogenic bowel, not elsewhere classified	0.000	0.747	0.253
K63.2 Fistula of intestine	0.001	0.769	0.231
K62.4 Stenosis of anus and rectum	0.000	0.770	0.230
K55.2 Angiodysplasia of colon	0.000	0.778	0.222
K62.3 Rectal prolapse	0.000	0.816	0.184
K60.3 Anal fistula	0.000	0.825	0.175
C67.9 Bladder, unspecified	0.154	0.846	0.000
C67 Malignant neoplasm of bladder	0.143	0.857	0.000
C67.6 Ureteric orifice	0.140	0.860	0.000
C67.2 Lateral wall of bladder	0.116	0.884	0.000
C67.3 Anterior wall of bladder	0.115	0.885	0.000
K61 Abscess of anal and rectal regions	0.001	0.888	0.111
C67.1 Dome of bladder	0.109	0.891	0.000
C67.4 Posterior wall of bladder	0.108	0.892	0.000
C67.7 Urachus	0.103	0.897	0.000
C67.0 Trigone of bladder	0.102	0.898	0.000
K60.2 Anal fissure, unspecified	0.000	0.902	0.098
C67.5 Bladder neck	0.095	0.905	0.000
K61.4 Intrasphincteric abscess	0.001	0.918	0.081
J98.0 Diseases of bronchus, not elsewhere classified	0.081	0.919	0.000
K61.1 Rectal abscess	0.001	0.923	0.077
C67.8 Overlapping lesion of bladder	0.076	0.924	0.000
K61.2 Anorectal abscess	0.001	0.930	0.069
C64-C68 Malignant neoplasms of urinary tract	0.058	0.942	0.000
C65 Malignant neoplasm of renal pelvis	0.050	0.950	0.000
C66 Malignant neoplasm of ureter	0.046	0.954	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.041	0.959	0.000
K62.5 Haemorrhage of anus and rectum	0.000	0.968	0.032
C68.9 Urinary organ, unspecified	0.032	0.968	0.000
C68.8 Overlapping lesion of urinary organs	0.030	0.970	0.000
C68.1 Paraurethral glands	0.030	0.970	0.000
K57 Diverticular disease of intestine	0.000	0.972	0.028
C68.0 Urethra	0.027	0.973	0.000
K61.3 Ischiorectal abscess	0.001	0.975	0.024
K58.9 Irritable bowel syndrome without diarrhoea	0.000	0.977	0.023
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.000	0.980	0.020
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.000	0.980	0.020
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.983	0.017
K57.0 Diverticular disease of small intestine with perforation and abscess	0.000	0.984	0.016
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.015	0.985	0.000
J98 Other respiratory disorders	0.014	0.986	0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.000	0.986	0.014
C18.0 Caecum	0.000	0.986	0.014
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.000	0.986	0.014
K57.2 Diverticular disease of large intestine with perforation and abscess	0.000	0.987	0.013
M89.9 Disorder of bone, unspecified	0.013	0.987	0.000
J98.6 Disorders of diaphragm	0.012	0.988	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.012	0.988	0.000
C18 Malignant neoplasm of colon	0.000	0.988	0.012
J98.5 Diseases of mediastinum, not elsewhere classified	0.011	0.988	0.000
C18.2 Ascending colon	0.000	0.989	0.011
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.011	0.989	0.000
C18.9 Colon, unspecified	0.000	0.989	0.011
J98.3 Compensatory emphysema	0.010	0.989	0.000
J98.2 Interstitial emphysema	0.010	0.990	0.000
M89 Other disorders of bone	0.010	0.990	0.000
J98.4 Other disorders of lung	0.010	0.990	0.000
K61.0 Anal abscess	0.001	0.990	0.010
C18.1 Appendix	0.000	0.990	0.010
M89.94 Disorder of bone, unspecified (Hand)	0.010	0.990	0.000
M89.8 Other specified disorders of bone	0.010	0.990	0.000
C18.8 Overlapping lesion of colon	0.000	0.990	0.009
L40.9 Psoriasis, unspecified	0.000	0.991	0.009
M89.99 Disorder of bone, unspecified (Site unspecified)	0.009	0.991	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.009	0.991	0.000
M89.92 Disorder of bone, unspecified (Upper arm)	0.009	0.991	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.009	0.991	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.009	0.991	0.000
J98.8 Other specified respiratory disorders	0.009	0.991	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.009	0.991	0.000
C18.5 Splenic flexure	0.000	0.991	0.009
M89.5 Osteolysis	0.009	0.991	0.000
K57.1 Diverticular disease of small intestine without perforation or abscess	0.000	0.991	0.009
M89.3 Hypertrophy of bone	0.009	0.991	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.009	0.991	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.009	0.991	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.008	0.992	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.008	0.992	0.000
M89.55 Osteolysis (Pelvic region and thigh)	0.008	0.992	0.000
N13 Obstructive and reflux uropathy	0.008	0.992	0.000
M89.6 Osteopathy after poliomyelitis	0.008	0.992	0.000
M89.2 Other disorders of bone development and growth	0.008	0.992	0.000
M89.1 Epiphyseal arrest	0.008	0.992	0.000
N13.8 Other obstructive and reflux uropathy	0.008	0.992	0.000
M89.88 Other specified disorders of bone (Other)	0.008	0.992	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.007	0.992	0.000
M89.98 Disorder of bone, unspecified (Other)	0.007	0.992	0.000
C18.3 Hepatic flexure	0.000	0.992	0.007
M89.37 Hypertrophy of bone (Ankle and foot)	0.007	0.993	0.000
C18.7 Sigmoid colon	0.000	0.993	0.007
M89.89 Other specified disorders of bone (Site unspecified)	0.007	0.993	0.000
M89.83 Other specified disorders of bone (Forearm)	0.007	0.993	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.007	0.993	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.007	0.993	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.000	0.993	0.007
N13.4 Hydroureter	0.007	0.993	0.000
N13.3 Other and unspecified hydronephrosis	0.007	0.993	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.007	0.993	0.000
M89.59 Osteolysis (Site unspecified)	0.006	0.993	0.000
M89.58 Osteolysis (Other)	0.006	0.993	0.000
M89.57 Osteolysis (Ankle and foot)	0.006	0.993	0.000
M89.56 Osteolysis (Lower leg)	0.006	0.993	0.000
M89.54 Osteolysis (Hand)	0.006	0.993	0.000
M89.53 Osteolysis (Forearm)	0.006	0.993	0.000
M89.52 Osteolysis (Upper arm)	0.006	0.993	0.000
M89.51 Osteolysis (Shoulder region)	0.006	0.993	0.000
M89.50 Osteolysis (Multiple sites)	0.006	0.993	0.000
C18.6 Descending colon	0.000	0.994	0.006
M89.39 Hypertrophy of bone (Site unspecified)	0.006	0.994	0.000
M89.38 Hypertrophy of bone (Other)	0.006	0.994	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.006	0.994	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.006	0.994	0.000
M89.34 Hypertrophy of bone (Hand)	0.006	0.994	0.000
M89.33 Hypertrophy of bone (Forearm)	0.006	0.994	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.006	0.994	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.006	0.994	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.006	0.994	0.000
M89.84 Other specified disorders of bone (Hand)	0.006	0.994	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.006	0.994	0.000
J98.9 Respiratory disorder, unspecified	0.006	0.994	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.994	0.006
M89.81 Other specified disorders of bone (Shoulder region)	0.006	0.994	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.000	0.994	0.006
C20 Malignant neoplasm of rectum	0.000	0.994	0.006
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.006	0.994	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.006	0.994	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.006	0.994	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.006	0.994	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.006	0.994	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.006	0.994	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.006	0.994	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.006	0.994	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.006	0.994	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.000	0.994	0.006
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.994	0.006
M89.0 Algoneurodystrophy	0.006	0.994	0.000
T85.2 Mechanical complication of intraocular lens	0.000	0.994	0.006
C15-C26 Malignant neoplasms of digestive organs	0.000	0.994	0.006
M89.19 Epiphyseal arrest (Site unspecified)	0.006	0.994	0.000
M89.18 Epiphyseal arrest (Other)	0.006	0.994	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.006	0.994	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.006	0.994	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.006	0.994	0.000
M89.14 Epiphyseal arrest (Hand)	0.006	0.994	0.000
M89.13 Epiphyseal arrest (Forearm)	0.006	0.994	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.006	0.994	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.006	0.994	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.006	0.994	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.006	0.994	0.000
M89.28 Other disorders of bone development and growth (Other)	0.006	0.994	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.006	0.994	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.006	0.994	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.006	0.994	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.006	0.994	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.006	0.994	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.006	0.994	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.006	0.994	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.006	0.994	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.006	0.994	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.006	0.994	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.006	0.994	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.006	0.994	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.006	0.994	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.006	0.994	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.006	0.994	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.006	0.994	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.006	0.994	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.006	0.994	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.006	0.994	0.000
C17 Malignant neoplasm of small intestine	0.000	0.994	0.006
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.000	0.994	0.005
C23 Malignant neoplasm of gallbladder	0.000	0.994	0.005
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.005	0.995	0.000
K56 Paralytic ileus and intestinal obstruction without hernia	0.001	0.995	0.005
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.000	0.995	0.005
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.000	0.995	0.005
K56.4 Other impaction of intestine	0.005	0.995	0.000
C17.9 Small intestine, unspecified	0.000	0.995	0.005
N13.7 Vesicoureteral-reflux-associated uropathy	0.005	0.995	0.000
S43.0 Dislocation of shoulder joint	0.005	0.995	0.000
C17.2 Ileum	0.000	0.995	0.005
N13.6 Pyonephrosis	0.005	0.995	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.005	0.995	0.000
C17.1 Jejunum	0.000	0.995	0.005
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.005	0.995	0.000
M89.04 Algoneurodystrophy (Hand)	0.004	0.995	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.000	0.995	0.005
T85.4 Mechanical complication of breast prosthesis and implant	0.000	0.995	0.004
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.995	0.004
M89.08 Algoneurodystrophy (Other)	0.004	0.996	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.004	0.996	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.004	0.996	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.004	0.996	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.004	0.996	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.004	0.996	0.000
C17.8 Overlapping lesion of small intestine	0.000	0.996	0.004
C17.3 Meckel's diverticulum	0.000	0.996	0.004
J95-J99 Other diseases of the respiratory system	0.004	0.996	0.000
C17.0 Duodenum	0.000	0.996	0.004
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
M89.09 Algoneurodystrophy (Site unspecified)	0.004	0.996	0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.996	0.004
S43.4 Sprain and strain of shoulder joint	0.004	0.996	0.000
G31.8 Other specified degenerative diseases of nervous system	0.004	0.996	0.000
R27.0 Ataxia, unspecified	0.000	0.996	0.004
M89.07 Algoneurodystrophy (Ankle and foot)	0.004	0.996	0.000
S43.1 Dislocation of acromioclavicular joint	0.004	0.996	0.000
S01.9 Open wound of head, part unspecified	0.000	0.996	0.004
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.996	0.004
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.004	0.996	0.000
S43.5 Sprain and strain of acromioclavicular joint	0.004	0.996	0.000
C18.4 Transverse colon	0.000	0.996	0.004
Z02.8 Other examinations for administrative purposes	0.000	0.996	0.004
M89.03 Algoneurodystrophy (Forearm)	0.003	0.996	0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.996	0.004
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.996	0.004
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.004	0.996	0.000
A08.4 Viral intestinal infection, unspecified	0.004	0.996	0.000
S62.60 Fracture of other finger (closed)	0.000	0.996	0.004
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.003	0.996	0.000
S43.6 Sprain and strain of sternoclavicular joint	0.003	0.996	0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.003	0.996	0.000
S43.2 Dislocation of sternoclavicular joint	0.003	0.996	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.000	0.996	0.004
S42.30 Fracture of shaft of humerus (closed)	0.004	0.996	0.000
K56.1 Intussusception	0.001	0.996	0.003
I12.0 Hypertensive renal disease with renal failure	0.000	0.996	0.004
S62.2 Fracture of first metacarpal bone	0.000	0.996	0.004
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.996	0.004
K56.3 Gallstone ileus	0.001	0.996	0.003
D05.0 Lobular carcinoma in situ	0.000	0.997	0.003
J95 Postprocedural respiratory disorders, not elsewhere classified	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
Z97.4 Presence of external hearing-aid	0.003	0.997	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.997	0.003
C26 Malignant neoplasm of other and ill-defined digestive organs	0.000	0.997	0.003
S62 Fracture at wrist and hand level	0.000	0.997	0.003
K70.1 Alcoholic hepatitis	0.003	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997	0.000
J96 Respiratory failure, not elsewhere classified	0.003	0.997	0.000
K56.7 Ileus, unspecified	0.000	0.997	0.003
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.000	0.997	0.003
J95.0 Tracheostomy malfunction	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.997	0.003
S49 Other and unspecified injuries of shoulder and upper arm	0.003	0.997	0.000
S62.6 Fracture of other finger	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
S63.6 Sprain and strain of finger(s)	0.000	0.997	0.003
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.997	0.003
D05 Carcinoma in situ of breast	0.000	0.997	0.003
J95.9 Postprocedural respiratory disorder, unspecified	0.003	0.997	0.000
K70 Alcoholic liver disease	0.003	0.997	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.997	0.003
S62.4 Multiple fractures of metacarpal bones	0.000	0.997	0.003
S62.1 Fracture of other carpal bone(s)	0.000	0.997	0.003
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.997	0.003
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.997	0.003
S62.5 Fracture of thumb	0.000	0.997	0.003
S42.3 Fracture of shaft of humerus	0.003	0.997	0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.997	0.003
S62.21 Fracture of first metacarpal bone (open)	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.000	0.997	0.003
S49.8 Other specified injuries of shoulder and upper arm	0.003	0.997	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
N10-N16 Renal tubulo-interstitial diseases	0.003	0.997	0.000
K56.0 Paralytic ileus	0.001	0.997	0.002
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.997	0.003
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.003
K70.0 Alcoholic fatty liver	0.003	0.997	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.003	0.997	0.000
J95.5 Postprocedural subglottic stenosis	0.003	0.997	0.000
J95.4 Mendelson's syndrome	0.003	0.997	0.000
J95.3 Chronic pulmonary insufficiency following surgery	0.003	0.997	0.000
J95.2 Acute pulmonary insufficiency following nonthoracic surgery	0.003	0.997	0.000
J95.1 Acute pulmonary insufficiency following thoracic surgery	0.003	0.997	0.000
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.997	0.003
C21 Malignant neoplasm of anus and anal canal	0.000	0.997	0.003
C15 Malignant neoplasm of oesophagus	0.000	0.997	0.003
S60-S69 Injuries to the wrist and hand	0.000	0.997	0.003
S49.9 Unspecified injury of shoulder and upper arm	0.003	0.997	0.000
C26.8 Overlapping lesion of digestive system	0.000	0.997	0.002
C26.1 Spleen	0.000	0.997	0.002
S40.8 Other superficial injuries of shoulder and upper arm	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.003	0.997	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S44 Injury of nerves at shoulder and upper arm level	0.003	0.997	0.000
S47 Crushing injury of shoulder and upper arm	0.003	0.997	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.003	0.997	0.000
J96.9 Respiratory failure, unspecified	0.002	0.997	0.000
J96.1 Chronic respiratory failure	0.002	0.997	0.000
J96.0 Acute respiratory failure	0.002	0.997	0.000
N11.9 Chronic tubulo-interstitial nephritis, unspecified	0.003	0.997	0.000
C25 Malignant neoplasm of pancreas	0.000	0.997	0.003
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.997	0.003
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.997	0.003
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.997	0.003
C24.8 Overlapping lesion of biliary tract	0.000	0.997	0.002
S61.1 Open wound of finger(s) with damage to nail	0.000	0.997	0.003
S63.5 Sprain and strain of wrist	0.000	0.997	0.003
N15 Other renal tubulo-interstitial diseases	0.003	0.997	0.000
I49.5 Sick sinus syndrome	0.003	0.997	0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.000	0.997	0.002
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.997	0.002
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.997	0.002
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.997	0.002
S68.4 Traumatic amputation of hand at wrist level	0.000	0.997	0.002
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.997	0.002
N11 Chronic tubulo-interstitial nephritis	0.003	0.997	0.000
S63.0 Dislocation of wrist	0.000	0.997	0.003
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.997	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.997	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.997	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.997	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.997	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.997	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.997	0.002
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.997	0.002
M86-M90 Other osteopathies	0.003	0.997	0.000
S49.7 Multiple injuries of shoulder and upper arm	0.002	0.997	0.000
C26.9 Ill-defined sites within the digestive system	0.000	0.997	0.002
N15.9 Renal tubulo-interstitial disease, unspecified	0.002	0.997	0.000
S46.1 Injury of muscle and tendon of long head of biceps	0.002	0.997	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.997	0.002
F99 Mental disorder, not otherwise specified	0.000	0.997	0.003
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.997	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.997	0.002
C24.9 Biliary tract, unspecified	0.000	0.998	0.002
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions	0.002	0.998	0.000
K70.9 Alcoholic liver disease, unspecified	0.002	0.998	0.000
S41 Open wound of shoulder and upper arm	0.002	0.998	0.000
D63.0 Anaemia in neoplastic disease	0.000	0.998	0.002
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.998	0.002
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.998	0.002
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.998	0.002
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.998	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
S46.3 Injury of muscle and tendon of triceps	0.002	0.998	0.000
S42 Fracture of shoulder and upper arm	0.002	0.998	0.000
S42.31 Fracture of shaft of humerus (open)	0.002	0.998	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.000	0.998	0.002
S63.1 Dislocation finger	0.000	0.998	0.002
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.998	0.002
S63.2 Multiple dislocations of fingers	0.000	0.998	0.002
C24.1 Ampulla of Vater	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere	0.002	0.998	0.000
S46.9 Injury of unspecified muscle and tendon at shoulder and upper arm level	0.002	0.998	0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
S46.7 Injury of multiple muscles and tendons at shoulder and upper arm level	0.002	0.998	0.000
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.998	0.002
C15.8 Overlapping lesion of oesophagus	0.000	0.998	0.002
C15.2 Abdominal part of oesophagus	0.000	0.998	0.002
C15.1 Thoracic part of oesophagus	0.000	0.998	0.002
C21.8 Overlapping lesion of rectum, anus and anal canal	0.000	0.998	0.002
C21.2 Cloacogenic zone	0.000	0.998	0.002
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.000	0.998	0.002
C25.1 Body of pancreas	0.000	0.998	0.002
N36.8 Other specified disorders of urethra	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.002	0.998	0.000
S44.9 Injury of unspecified nerve at shoulder and upper arm level	0.002	0.998	0.000
S44.8 Injury of other nerves at shoulder and upper arm level	0.002	0.998	0.000
S44.7 Injury of multiple nerves at shoulder and upper arm level	0.002	0.998	0.000
S44.5 Injury of cutaneous sensory nerve at shoulder and upper arm level	0.002	0.998	0.000
S44.4 Injury of musculocutaneous nerve	0.002	0.998	0.000
S44.3 Injury of axillary nerve	0.002	0.998	0.000
S44.2 Injury of radial nerve at upper arm level	0.002	0.998	0.000
S44.1 Injury of median nerve at upper arm level	0.002	0.998	0.000
S44.0 Injury of ulnar nerve at upper arm level	0.002	0.998	0.000
S45.9 Injury of unspecified blood vessel at shoulder and upper arm level	0.002	0.998	0.000
S45.8 Injury of other blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S45.7 Injury of multiple blood vessels at shoulder and upper arm level	0.002	0.998	0.000
S45.3 Injury of superficial vein at shoulder and upper arm level	0.002	0.998	0.000
S45.2 Injury of axillary or brachial vein	0.002	0.998	0.000
S45.1 Injury of brachial artery	0.002	0.998	0.000
S45.0 Injury of axillary artery	0.002	0.998	0.000
S48.9 Traumatic amputation of shoulder and upper arm, level unspecified	0.002	0.998	0.000
S48.1 Traumatic amputation at level between shoulder and elbow	0.002	0.998	0.000
S48.0 Traumatic amputation at shoulder joint	0.002	0.998	0.000
C24.0 Extrahepatic bile duct	0.000	0.998	0.002
C25.8 Overlapping lesion of pancreas	0.000	0.998	0.002
C25.7 Other parts of pancreas	0.000	0.998	0.002
C25.4 Endocrine pancreas	0.000	0.998	0.002
N14.1 Nephropathy induced by other drugs, medicaments and biological substances	0.002	0.998	0.000
S46.0 Injury of tendon of the rotator cuff of shoulder	0.002	0.998	0.000
J96.09 Acute respiratory failure; Type unspecified	0.002	0.998	0.000
J96.01 Acute respiratory failure; Type II [hypercapnic]	0.002	0.998	0.000
J96.00 Acute respiratory failure; Type I [hypoxic]	0.002	0.998	0.000
J96.19 Chronic respiratory failure; Type unspecified	0.002	0.998	0.000
J96.11 Chronic respiratory failure; Type II [hypercapnic]	0.002	0.998	0.000
J96.10 Chronic respiratory failure; Type I [hypoxic]	0.002	0.998	0.000
J96.99 Respiratory failure, unspecified; Type unspecified	0.002	0.998	0.000
J96.91 Respiratory failure unspecified; Type II [hypercapnic]	0.002	0.998	0.000
J96.90 Respiratory failure, unspecified; Type I [hypoxic]	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
E22 Hyperfunction of pituitary gland	0.000	0.998	0.002
S67 Crushing injury of wrist and hand	0.000	0.998	0.002
C25.2 Tail of pancreas	0.000	0.998	0.002
N15.8 Other specified renal tubulo-interstitial diseases	0.002	0.998	0.000
N15.1 Renal and perinephric abscess	0.002	0.998	0.000
N15.0 Balkan nephropathy	0.002	0.998	0.000
E34.9 Endocrine disorder, unspecified	0.000	0.998	0.002
N11.8 Other chronic tubulo-interstitial nephritis	0.002	0.998	0.000
S62.7 Multiple fractures of fingers	0.000	0.998	0.002
C15.3 Upper third of oesophagus	0.000	0.998	0.002
D05.7 Other carcinoma in situ of breast	0.000	0.998	0.002
G54.9 Nerve root and plexus disorder, unspecified	0.000	0.998	0.002
C25.3 Pancreatic duct	0.000	0.998	0.002
M88 Paget's disease of bone [osteitis deformans]	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.002	0.998	0.000
C16 Malignant neoplasm of stomach	0.000	0.998	0.002
J99 Respiratory disorders in diseases classified elsewhere	0.002	0.998	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.998	0.002
C15.0 Cervical part of oesophagus	0.000	0.998	0.002
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.002	0.998	0.000
N11.0 Nonobstructive reflux-associated chronic pyelonephritis	0.002	0.998	0.000
N14.4 Toxic nephropathy, not elsewhere classified	0.002	0.998	0.000
N14.3 Nephropathy induced by heavy metals	0.002	0.998	0.000
N14.2 Nephropathy induced by unspecified drug, medicament or biological substance	0.002	0.998	0.000
N14.0 Analgesic nephropathy	0.002	0.998	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
S42.8 Fracture of other parts of shoulder and upper arm	0.002	0.998	0.000
N11.1 Chronic obstructive pyelonephritis	0.002	0.998	0.000
E10.4 With neurological complications	0.000	0.998	0.002
S46.2 Injury of muscle and tendon of other parts of biceps	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations