TreeWAS – Variant ID: rs11717635

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
I30-I52 Other forms of heart disease	1.000	0.000
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
Chapter IX Diseases of the circulatory system	1.000	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	1.000	0.000
I50 Heart failure	1.000	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.999	0.001
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.998	0.002
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.998	0.002
C34 Malignant neoplasm of bronchus and lung	0.996	0.004
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.993	0.007
I42 Cardiomyopathy	0.989	0.011
I47 Paroxysmal tachycardia	0.988	0.012
I50.0 Congestive heart failure	0.983	0.017
I47.1 Supraventricular tachycardia	0.982	0.018
Chapter X Diseases of the respiratory system	0.982	0.018
I50.1 Left ventricular failure	0.982	0.018
C79 Secondary malignant neoplasm of other sites	0.979	0.021
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.979	0.021
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.979	0.021
O20-O29 Other maternal disorders predominantly related to pregnancy	0.978	0.022
C34.3 Lower lobe, bronchus or lung	0.978	0.022
Chapter VIII Diseases of the ear and mastoid process	0.977	0.023
Chapter I Certain infectious and parasitic diseases	0.976	0.024
R00 Abnormalities of heart beat	0.974	0.026
J40-J47 Chronic lower respiratory diseases	0.971	0.029
I50.9 Heart failure, unspecified	0.959	0.041
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.959	0.041
T36-T50 Poisoning by drugs, medicaments and biological substances	0.957	0.043
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.957	0.043
C34.9 Bronchus or lung, unspecified	0.947	0.053
O20 Haemorrhage in early pregnancy	0.946	0.054
R00.2 Palpitations	0.944	0.056
C51-C58 Malignant neoplasms of female genital organs	0.943	0.057
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.942	0.058
I44 Atrioventricular and left bundle-branch block	0.941	0.059
J44 Other chronic obstructive pulmonary disease	0.936	0.064
J43 Emphysema	0.936	0.064
C78.2 Secondary malignant neoplasm of pleura	0.936	0.064
I05-I09 Chronic rheumatic heart diseases	0.935	0.065
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.931	0.069
R00.0 Tachycardia, unspecified	0.927	0.073
J80-J84 Other respiratory diseases principally affecting the interstitium	0.925	0.075
O60-O75 Complications of labour and delivery	0.912	0.088
R01 Cardiac murmurs and other cardiac sounds	0.911	0.089
H65-H75 Diseases of middle ear and mastoid	0.910	0.090
R03 Abnormal blood-pressure reading, without diagnosis	0.908	0.092
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.907	0.093
T66-T78 Other and unspecified effects of external causes	0.906	0.094
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.904	0.096
O00-O08 Pregnancy with abortive outcome	0.903	0.097
H90-H95 Other disorders of ear	0.902	0.098
J43.9 Emphysema, unspecified	0.901	0.099
C80 Malignant neoplasm without specification of site	0.895	0.105
O36 Maternal care for other known or suspected foetal problems	0.893	0.107
B95-B98 Bacterial, viral and other infectious agents	0.890	0.110
J81 Pulmonary oedema	0.890	0.110
I08 Multiple valve diseases	0.887	0.113
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.887	0.113
Chapter XXII Codes for special purposes	0.884	0.116
O20.0 Threatened abortion	0.880	0.120
C78.0 Secondary malignant neoplasm of lung	0.880	0.120
I70-I79 Diseases of arteries, arterioles and capillaries	0.879	0.121
I42.1 Obstructive hypertrophic cardiomyopathy	0.879	0.121
R03.1 Nonspecific low blood-pressure reading	0.876	0.124
J60-J70 Lung diseases due to external agents	0.870	0.129
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.870	0.130
R73 Elevated blood glucose level	0.867	0.133
C34.1 Upper lobe, bronchus or lung	0.864	0.136
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.863	0.137
I42.0 Dilated cardiomyopathy	0.862	0.138
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.861	0.139
J47 Bronchiectasis	0.859	0.141
R79 Other abnormal findings of blood chemistry	0.859	0.141
R01.1 Cardiac murmur, unspecified	0.858	0.142
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.858	0.142
S60-S69 Injuries to the wrist and hand	0.855	0.145
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.854	0.146
O20.9 Haemorrhage in early pregnancy, unspecified	0.853	0.147
S80-S89 Injuries to the knee and lower leg	0.852	0.148
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters	0.851	0.149
C56 Malignant neoplasm of ovary	0.847	0.153
I46 Cardiac arrest	0.845	0.155
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.845	0.155
T78 Adverse effects, not elsewhere classified	0.844	0.156
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.843	0.157
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.843	0.157
O03 Spontaneous abortion	0.843	0.157
H90 Conductive and sensorineural hearing loss	0.842	0.158
J44.9 Chronic obstructive pulmonary disease, unspecified	0.842	0.158
I42.9 Cardiomyopathy, unspecified	0.838	0.162
I42.2 Other hypertrophic cardiomyopathy	0.836	0.164
I08.0 Disorders of both mitral and aortic valves	0.836	0.164
C78.7 Secondary malignant neoplasm of liver	0.835	0.165
C79.6 Secondary malignant neoplasm of ovary	0.830	0.170
O36.8 Maternal care for other specified foetal problems	0.822	0.178
R09.1 Pleurisy	0.819	0.181
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.817	0.183
J09-J18 Influenza and pneumonia	0.815	0.185
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.814	0.186
O34 Maternal care for known or suspected abnormality of pelvic organs	0.812	0.188
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters	0.809	0.191
B35-B49 Mycoses	0.809	0.191
O03.9 Complete or unspecified, without complication	0.808	0.192
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.807	0.193
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.802	0.198
O26 Maternal care for other conditions predominantly related to pregnancy	0.801	0.199
T39.1 4-Aminophenol derivatives	0.800	0.200
O40 Polyhydramnios	0.800	0.200
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.799	0.201
Chapter XX External causes of morbidity and mortality	0.799	0.201
B07 Viral warts	0.799	0.201
I44.0 Atrioventricular block, first degree	0.799	0.201
C78.4 Secondary malignant neoplasm of small intestine	0.798	0.202
I42.8 Other cardiomyopathies	0.797	0.203
S10-S19 Injuries to the neck	0.795	0.205
O68 Labour and delivery complicated by foetal stress [distress]	0.794	0.206
D60-D64 Aplastic and other anaemias	0.793	0.207
I44.2 Atrioventricular block, complete	0.793	0.207
R74 Abnormal serum enzyme levels	0.793	0.207
R47-R49 Symptoms and signs involving speech and voice	0.791	0.209
T40.2 Other opioids	0.789	0.211
H74 Other disorders of middle ear and mastoid	0.788	0.212
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.788	0.212
H65 Nonsuppurative otitis media	0.786	0.214
C80.9 Malignant neoplasm, unspecified	0.786	0.214
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.785	0.215
R79.8 Other specified abnormal findings of blood chemistry	0.782	0.218
I60-I69 Cerebrovascular diseases	0.780	0.220
T20-T25 Burns and corrosions of external body surface, specified by site	0.778	0.222
I73 Other peripheral vascular diseases	0.776	0.224
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.776	0.224
C53 Malignant neoplasm of cervix uteri	0.776	0.224
Q60-Q64 Congenital malformations of the urinary system	0.775	0.225
R09.0 Asphyxia	0.772	0.228
S40-S49 Injuries to the shoulder and upper arm	0.772	0.228
C79.2 Secondary malignant neoplasm of skin	0.769	0.230
O36.6 Maternal care for excessive foetal growth	0.768	0.232
R73.0 Abnormal glucose tolerance test	0.768	0.232
I42.6 Alcoholic cardiomyopathy	0.767	0.233
D63 Anaemia in chronic diseases classified elsewhere	0.765	0.235
I49 Other cardiac arrhythmias	0.765	0.235
S90-S99 Injuries to the ankle and foot	0.764	0.236
S62 Fracture at wrist and hand level	0.761	0.238
S82 Fracture of lower leg, including ankle	0.761	0.239
R00.8 Other and unspecified abnormalities of heart beat	0.760	0.240
I27 Other pulmonary heart diseases	0.759	0.241
C32 Malignant neoplasm of larynx	0.757	0.243
O21 Excessive vomiting in pregnancy	0.757	0.243
B50-B64 Protozoal diseases	0.754	0.246
O43 Placental disorders	0.754	0.246
A50-A64 Infections with a predominantly sexual mode of transmission	0.754	0.246
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.754	0.246
O75 Other complications of labour and delivery, not elsewhere classified	0.754	0.246
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.750	0.250
D63.0 Anaemia in neoplastic disease	0.750	0.250
I72 Other aneurysm	0.749	0.251
J43.2 Centrilobular emphysema	0.747	0.253
I44.7 Left bundle-branch block, unspecified	0.746	0.254
R72 Abnormality of white blood cells, not elsewhere classified	0.745	0.255
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.743	0.257
I34 Nonrheumatic mitral valve disorders	0.743	0.257
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.743	0.257
O26.9 Pregnancy-related condition, unspecified	0.741	0.258
C54 Malignant neoplasm of corpus uteri	0.740	0.260
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.735	0.264
H72 Perforation of tympanic membrane	0.733	0.267
H60-H62 Diseases of external ear	0.733	0.267
Q20-Q28 Congenital malformations of the circulatory system	0.732	0.268
R71 Abnormality of red blood cells	0.730	0.270
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.730	0.270
R02 Gangrene, not elsewhere classified	0.729	0.271
H93 Other disorders of ear, not elsewhere classified	0.729	0.271
O48 Prolonged pregnancy	0.728	0.272
B90-B94 Sequelae of infectious and parasitic diseases	0.726	0.274
A30-A49 Other bacterial diseases	0.725	0.275
I70 Atherosclerosis	0.724	0.276
I44.6 Other and unspecified fascicular block	0.723	0.277
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.722	0.277
C80.0 Malignant neoplasm, primary site unknown, so stated	0.722	0.278
H65.3 Chronic mucoid otitis media	0.722	0.278
Y95 Nosocomial condition	0.721	0.279
I33 Acute and subacute endocarditis	0.721	0.279
H90.2 Conductive hearing loss, unspecified	0.719	0.281
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.718	0.282
I52 Other heart disorders in diseases classified elsewhere	0.717	0.283
I48 Atrial fibrillation and flutter	0.717	0.283
I43 Cardiomyopathy in diseases classified elsewhere	0.717	0.283
I41 Myocarditis in diseases classified elsewhere	0.717	0.283
I40 Acute myocarditis	0.717	0.283
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.717	0.283
I37 Pulmonary valve disorders	0.717	0.283
I36 Nonrheumatic tricuspid valve disorders	0.717	0.283
I32 Pericarditis in diseases classified elsewhere	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
I00-I02 Acute rheumatic fever	0.717	0.283
C76 Malignant neoplasm of other and ill-defined sites	0.717	0.283
O85-O92 Complications predominantly related to the puerperium	0.717	0.283
O24 Diabetes mellitus in pregnancy	0.717	0.283
O42 Premature rupture of membranes	0.717	0.283
C34.0 Main bronchus	0.716	0.284
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters	0.716	0.284
I38 Endocarditis, valve unspecified	0.716	0.284
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.715	0.284
C78.1 Secondary malignant neoplasm of mediastinum	0.715	0.284
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.715	0.285
C38 Malignant neoplasm of heart, mediastinum and pleura	0.715	0.285
C31 Malignant neoplasm of accessory sinuses	0.715	0.285
C30 Malignant neoplasm of nasal cavity and middle ear	0.715	0.285
C37 Malignant neoplasm of thymus	0.715	0.285
C33 Malignant neoplasm of trachea	0.715	0.285
C34.8 Overlapping lesion of bronchus and lung	0.714	0.286
C34.2 Middle lobe, bronchus or lung	0.714	0.286
S69 Other and unspecified injuries of wrist and hand	0.712	0.288
T33-T35 Frostbite	0.712	0.288
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.288
T00-T07 Injuries involving multiple body regions	0.712	0.288
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.712	0.288
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.712	0.288
I46.0 Cardiac arrest with successful resuscitation	0.711	0.289
S61 Open wound of wrist and hand	0.711	0.289
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.710	0.290
D80-D89 Certain disorders involving the immune mechanism	0.710	0.290
R00.1 Bradycardia, unspecified	0.710	0.290
T78.2 Anaphylactic shock, unspecified	0.709	0.291
I42.7 Cardiomyopathy due to drugs and other external agents	0.709	0.291
I42.5 Other restrictive cardiomyopathy	0.709	0.291
I42.4 Endocardial fibroelastosis	0.709	0.291
I42.3 Endomyocardial (eosinophilic) disease	0.709	0.291
I47.0 Reentry ventricular arrhythmia	0.708	0.292
O70 Perineal laceration during delivery	0.708	0.292
R73.9 Hyperglycaemia, unspecified	0.707	0.293
O35 Maternal care for known or suspected foetal abnormality and damage	0.705	0.295
O23 Infections of genito-urinary tract in pregnancy	0.705	0.295
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.704	0.296
J40 Bronchitis, not specified as acute or chronic	0.704	0.296
J13 Pneumonia due to Streptococcus pneumoniae	0.704	0.296
C79.8 Secondary malignant neoplasm of other specified sites	0.703	0.297
O02 Other abnormal products of conception	0.703	0.297
C55 Malignant neoplasm of uterus, part unspecified	0.702	0.297
B15-B19 Viral hepatitis	0.702	0.297
T80 Complications following infusion, transfusion and therapeutic injection	0.702	0.298
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.702	0.298
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.702	0.298
T78.4 Allergy, unspecified	0.702	0.298
R95-R99 Ill-defined and unknown causes of mortality	0.702	0.298
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.702	0.298
O29 Complications of anaesthesia during pregnancy	0.701	0.299
O28 Abnormal findings on antenatal screening of mother	0.701	0.299
O22 Venous complications in pregnancy	0.701	0.299
O25 Malnutrition in pregnancy	0.701	0.299
A80-A89 Viral infections of the central nervous system	0.701	0.299
I44.1 Atrioventricular block, second degree	0.700	0.300
B99-B99 Other infectious diseases	0.700	0.300
B85-B89 Pediculosis, acariasis and other infestations	0.700	0.300
B65-B83 Helminthiases	0.700	0.300
B20-B24 Human immunodeficiency virus [HIV] disease	0.700	0.300
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.700	0.300
A75-A79 Rickettsioses	0.700	0.300
A70-A74 Other diseases caused by chlamydiae	0.700	0.300
A65-A69 Other spirochaetal diseases	0.700	0.300
A20-A28 Certain zoonotic bacterial diseases	0.700	0.300
A15-A19 Tuberculosis	0.700	0.300
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.698	0.302
I60 Subarachnoid haemorrhage	0.698	0.302
J41 Simple and mucopurulent chronic bronchitis	0.696	0.303
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.696	0.304
C79.7 Secondary malignant neoplasm of adrenal gland	0.695	0.305
O66 Other obstructed labour	0.694	0.305
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.694	0.306
O94-O99 Other obstetric conditions, not elsewhere classified	0.693	0.307
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.693	0.307
H69 Other disorders of Eustachian tube	0.691	0.309
T50.9 Other and unspecified drugs, medicaments and biological substances	0.690	0.310
O64 Obstructed labour due to malposition and malpresentation of foetus	0.690	0.310
O34.7 Maternal care for abnormality of vulva and perineum	0.690	0.310
H80-H83 Diseases of inner ear	0.688	0.311
I27.0 Primary pulmonary hypertension	0.688	0.312
I95-I99 Other and unspecified disorders of the circulatory system	0.688	0.312
O45 Premature separation of placenta [abruptio placentae]	0.687	0.313
O44 Placenta praevia	0.687	0.313
O33 Maternal care for known or suspected disproportion	0.687	0.313
O31 Complications specific to multiple gestation	0.687	0.313
S62.6 Fracture of other finger	0.687	0.313
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.686	0.314
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.686	0.314
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.686	0.314
T46 Poisoning by agents primarily affecting the cardiovascular system	0.686	0.314
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.686	0.314
T41 Poisoning by anaesthetics and therapeutic gases	0.686	0.314
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.686	0.314
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.686	0.314
T36 Poisoning by systemic antibiotics	0.686	0.314
R78 Findings of drugs and other substances, not normally found in blood	0.686	0.314
R77 Other abnormalities of plasma proteins	0.686	0.314
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.686	0.314
B00 Herpesviral [herpes simplex] infections	0.686	0.314
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.684	0.316
T79-T79 Certain early complications of trauma	0.684	0.316
T78.1 Other adverse food reactions, not elsewhere classified	0.684	0.316
H71 Cholesteatoma of middle ear	0.683	0.317
S82.8 Fractures of other parts of lower leg	0.683	0.317
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.683	0.317
S86 Injury of muscle and tendon at lower leg level	0.683	0.317
T40.6 Other and unspecified narcotics	0.682	0.318
C49 Malignant neoplasm of other connective and soft tissue	0.682	0.318
Q80-Q89 Other congenital malformations	0.680	0.320
T88 Other complications of surgical and medical care, not elsewhere classified	0.679	0.321
O20.8 Other haemorrhage in early pregnancy	0.678	0.321
I07 Rheumatic tricuspid valve diseases	0.678	0.322
O30 Multiple gestation	0.678	0.322
I05 Rheumatic mitral valve diseases	0.677	0.323
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.676	0.323
I08.1 Disorders of both mitral and tricuspid valves	0.676	0.324
R74.8 Abnormal levels of other serum enzymes	0.676	0.324
C57 Malignant neoplasm of other and unspecified female genital organs	0.676	0.324
C58 Malignant neoplasm of placenta	0.676	0.324
C52 Malignant neoplasm of vagina	0.676	0.324
T82.3 Mechanical complication of other vascular grafts	0.676	0.324
R01.0 Benign and innocent cardiac murmurs	0.675	0.325
C51 Malignant neoplasm of vulva	0.674	0.325
I44.5 Left posterior fascicular block	0.674	0.325
I44.4 Left anterior fascicular block	0.674	0.325
I44.3 Other and unspecified atrioventricular block	0.674	0.325
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.672	0.328
J43.8 Other emphysema	0.671	0.329
J43.1 Panlobular emphysema	0.671	0.329
J43.0 MacLeod's syndrome	0.671	0.329
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.671	0.329
C10 Malignant neoplasm of oropharynx	0.671	0.329
I09 Other rheumatic heart diseases	0.671	0.329
I06 Rheumatic aortic valve diseases	0.671	0.329
R93 Abnormal findings on diagnostic imaging of other body structures	0.670	0.330
Q61 Cystic kidney disease	0.670	0.330
I08.8 Other multiple valve diseases	0.667	0.332
O63 Long labour	0.667	0.333
T78.0 Anaphylactic shock due to adverse food reaction	0.666	0.334
J82 Pulmonary eosinophilia, not elsewhere classified	0.663	0.336
J80 Adult respiratory distress syndrome	0.663	0.336
O62 Abnormalities of forces of labour	0.663	0.337
C88 Malignant immunoproliferative diseases	0.663	0.337
I49.9 Cardiac arrhythmia, unspecified	0.663	0.337
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.663	0.337
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters	0.663	0.337
J69 Pneumonitis due to solids and liquids	0.662	0.338
O61 Failed induction of labour	0.662	0.338
I47.9 Paroxysmal tachycardia, unspecified	0.661	0.339
T45.5 Anticoagulants	0.661	0.339
B97 Viral agents as the cause of diseases classified to other chapters	0.659	0.341
R06 Abnormalities of breathing	0.659	0.341
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.657	0.343
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.656	0.343
C53.9 Cervix uteri, unspecified	0.656	0.344
R49 Voice disturbances	0.656	0.344
S62.61 Fracture of other finger (open)	0.656	0.344
B02 Zoster [herpes zoster]	0.656	0.344
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.656	0.344
T81 Complications of procedures, not elsewhere classified	0.656	0.344
I30 Acute pericarditis	0.655	0.344
O74 Complications of anaesthesia during labour and delivery	0.654	0.346
O71 Other obstetric trauma	0.654	0.346
O65 Obstructed labour due to maternal pelvic abnormality	0.654	0.346
O60 Preterm delivery	0.654	0.346
R01.2 Other cardiac sounds	0.653	0.347
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.652	0.347
H70 Mastoiditis and related conditions	0.652	0.347
H68 Eustachian salpingitis and obstruction	0.652	0.347
H67 Otitis media in diseases classified elsewhere	0.652	0.347
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.652	0.348
O69 Labour and delivery complicated by umbilical cord complications	0.652	0.348
I73.0 Raynaud's syndrome	0.652	0.348
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.652	0.348
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.652	0.348
S70-S79 Injuries to the hip and thigh	0.652	0.348
O36.9 Maternal care for foetal problem, unspecified	0.651	0.349
T87 Complications peculiar to reattachment and amputation	0.651	0.349
R09.3 Abnormal sputum	0.650	0.349
D62 Acute posthaemorrhagic anaemia	0.650	0.350
R09.2 Respiratory arrest	0.650	0.350
T75 Effects of other external causes	0.650	0.350
T74 Maltreatment syndromes	0.650	0.350
T73 Effects of other deprivation	0.650	0.350
T70 Effects of air pressure and water pressure	0.650	0.350
T69 Other effects of reduced temperature	0.650	0.350
T67 Effects of heat and light	0.650	0.350
T71 Asphyxiation	0.650	0.350
T68 Hypothermia	0.650	0.350
T66 Unspecified effects of radiation	0.650	0.350
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.650	0.350
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.649	0.351
C83 Diffuse non-Hodgkin's lymphoma	0.649	0.351
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.648	0.352
Q35-Q37 Cleft lip and cleft palate	0.648	0.352
Q30-Q34 Congenital malformations of the respiratory system	0.648	0.352
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.648	0.352
O08 Complications following abortion and ectopic and molar pregnancy	0.648	0.352
O07 Failed attempted abortion	0.648	0.352
O06 Unspecified abortion	0.648	0.352
O05 Other abortion	0.648	0.352
O01 Hydatidiform mole	0.648	0.352
I49.3 Ventricular premature depolarisation	0.647	0.353
H94 Other disorders of ear in diseases classified elsewhere	0.646	0.353
I46.9 Cardiac arrest, unspecified	0.646	0.353
B36 Other superficial mycoses	0.646	0.354
I73.9 Peripheral vascular disease, unspecified	0.646	0.354
Q50-Q56 Congenital malformations of genital organs	0.645	0.355
T82.1 Mechanical complication of cardiac electronic device	0.644	0.356
Q38-Q45 Other congenital malformations of the digestive system	0.644	0.356
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters	0.643	0.357
Q00-Q07 Congenital malformations of the nervous system	0.642	0.358
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.640	0.360
O36.4 Maternal care for intra-uterine death	0.640	0.360
O36.3 Maternal care for signs of foetal hypoxia	0.640	0.360
O36.2 Maternal care for hydrops foetalis	0.640	0.360
O36.1 Maternal care for other isoimmunisation	0.640	0.360
H74.8 Other specified disorders of middle ear and mastoid	0.640	0.360
J44.8 Other specified chronic obstructive pulmonary disease	0.640	0.360
Q21 Congenital malformations of cardiac septa	0.639	0.361
X60-X84 Intentional self-harm	0.639	0.361
H74.3 Other acquired abnormalities of ear ossicles	0.639	0.361
H90.0 Conductive hearing loss, bilateral	0.638	0.362
C90 Multiple myeloma and malignant plasma cell neoplasms	0.637	0.363
S82.5 Fracture of medial malleolus	0.637	0.363
I08.9 Multiple valve disease, unspecified	0.636	0.364
I08.2 Disorders of both aortic and tricuspid valves	0.636	0.364
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.636	0.364
B06 Rubella [German measles]	0.636	0.364
B05 Measles	0.636	0.364
B01 Varicella [chickenpox]	0.636	0.364
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.636	0.364
B04 Monkeypox	0.636	0.364
B03 Smallpox	0.636	0.364
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract	0.635	0.365
I78 Diseases of capillaries	0.634	0.366
O41 Other disorders of amniotic fluid and membranes	0.634	0.366
S61.9 Open wound of wrist and hand, part unspecified	0.634	0.366
S20-S29 Injuries to the thorax	0.633	0.366
S80 Superficial injury of lower leg	0.633	0.367
I51 Complications and ill-defined descriptions of heart disease	0.632	0.368
J15 Bacterial pneumonia, not elsewhere classified	0.631	0.369
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.630	0.370
U80 Agent resistant to penicillin and related antibiotics	0.629	0.371
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.629	0.371
R79.0 Abnormal level of blood mineral	0.629	0.371
O04 Medical abortion	0.628	0.372
S50-S59 Injuries to the elbow and forearm	0.627	0.372
J84 Other interstitial pulmonary diseases	0.627	0.372
S82.80 Fractures of other parts of lower leg (closed)	0.627	0.373
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.627	0.373
C77.2 Intra-abdominal lymph nodes	0.627	0.373
O36.5 Maternal care for poor foetal growth	0.626	0.373
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.625	0.375
Chapter V Mental and behavioural disorders	0.625	0.375
B44 Aspergillosis	0.625	0.375
T23 Burn and corrosion of wrist and hand	0.624	0.375
J70 Respiratory conditions due to other external agents	0.624	0.376
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.624	0.376
J67 Hypersensitivity pneumonitis due to organic dust	0.624	0.376
J66 Airway disease due to specific organic dust	0.624	0.376
J63 Pneumoconiosis due to other inorganic dusts	0.624	0.376
J62 Pneumoconiosis due to dust containing silica	0.624	0.376
J65 Pneumoconiosis associated with tuberculosis	0.624	0.376
J64 Unspecified pneumoconiosis	0.624	0.376
J60 Coalworker's pneumoconiosis	0.624	0.376
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.624	0.376
T40.8 Lysergide [LSD]	0.624	0.376
T40.7 Cannabis (derivatives)	0.624	0.376
T40.5 Cocaine	0.624	0.376
T40.4 Other synthetic narcotics	0.624	0.376
T40.3 Methadone	0.624	0.376
T40.1 Heroin	0.624	0.376
T40.0 Opium	0.624	0.376
R79.9 Abnormal finding of blood chemistry, unspecified	0.624	0.376
S49 Other and unspecified injuries of shoulder and upper arm	0.623	0.377
S19 Other and unspecified injuries of neck	0.622	0.378
S61.1 Open wound of finger(s) with damage to nail	0.622	0.378
O47 False labour	0.619	0.380
O43.1 Malformation of placenta	0.619	0.381
J42 Unspecified chronic bronchitis	0.618	0.381
S82.4 Fracture of fibula alone	0.618	0.382
D55-D59 Haemolytic anaemias	0.618	0.382
D37-D48 Neoplasms of uncertain or unknown behaviour	0.617	0.383
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.615	0.385
C46 Kaposi's sarcoma	0.615	0.385
I47.2 Ventricular tachycardia	0.615	0.385
W00-W19 Falls	0.615	0.385
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.615	0.385
O34.2 Maternal care due to uterine scar from previous surgery	0.615	0.385
C09 Malignant neoplasm of tonsil	0.614	0.386
R76 Other abnormal immunological findings in serum	0.614	0.386
S65 Injury of blood vessels at wrist and hand level	0.613	0.387
I45 Other conduction disorders	0.613	0.387
I34.0 Mitral (valve) insufficiency	0.612	0.388
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.612	0.388
C91 Lymphoid leukaemia	0.611	0.389
S88 Traumatic amputation of lower leg	0.611	0.389
S87 Crushing injury of lower leg	0.611	0.389
S85 Injury of blood vessels at lower leg level	0.611	0.389

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations