TreeWAS – Variant ID: rs117492019

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.149	0.851	0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]	0.080	0.920	0.000
T22.2 Burn of second degree of shoulder and upper limb, except wrist and hand	0.065	0.935	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.065	0.935	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.060	0.940	0.000
M72.08 Palmar fascial fibromatosis [Dupuytren]-Other	0.058	0.942	0.000
M72.07 Palmar fascial fibromatosis [Dupuytren]-Ankle/Foot	0.058	0.942	0.000
M72.06 Palmar fascial fibromatosis [Dupuytren]-Lower Leg	0.058	0.942	0.000
M72.05 Palmar fascial fibromatosis [Dupuytren]-Pelvic/Thigh	0.058	0.942	0.000
M72.03 Palmar fascial fibromatosis [Dupuytren]-Forearm	0.058	0.942	0.000
M72.02 Palmar fascial fibromatosis [Dupuytren]-Upper arm	0.058	0.942	0.000
M72.01 Palmar fascial fibromatosis [Dupuytren]-Shldr region	0.058	0.942	0.000
M72.00 Palmar fascial fibromatosis [Dupuytren]-Mult sites	0.058	0.942	0.000
M72.09 Palmar fascial fibromatosis [Dupuytren]-Site unspec	0.057	0.943	0.000
T20 Burn and corrosion of head and neck	0.055	0.944	0.000
T22.0 Burn of unspecified degree of shoulder and upper limb, except wrist and hand	0.054	0.946	0.000
T22.1 Burn of first degree of shoulder and upper limb, except wrist and hand	0.054	0.946	0.000
T23 Burn and corrosion of wrist and hand	0.053	0.947	0.000
T20.2 Burn of second degree of head and neck	0.052	0.948	0.000
T21 Burn and corrosion of trunk	0.052	0.948	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.051	0.949	0.000
T25 Burn and corrosion of ankle and foot	0.048	0.952	0.000
T21.2 Burn of second degree of trunk	0.048	0.952	0.000
T23.2 Burn of second degree of wrist and hand	0.047	0.953	0.000
T22.7 Corrosion of third degree of shoulder and upper limb, except wrist and hand	0.046	0.953	0.000
T22.6 Corrosion of second degree of shoulder and upper limb, except wrist and hand	0.046	0.953	0.000
T22.5 Corrosion of first degree of shoulder and upper limb, except wrist and hand	0.046	0.953	0.000
T22.4 Corrosion of unspecified degree of shoulder and upper limb, except wrist and hand	0.046	0.953	0.000
T23.3 Burn of third degree of wrist and hand	0.044	0.956	0.000
T20.1 Burn of first degree of head and neck	0.041	0.959	0.000
T20.7 Corrosion of third degree of head and neck	0.040	0.960	0.000
T20.6 Corrosion of second degree of head and neck	0.040	0.960	0.000
T20.5 Corrosion of first degree of head and neck	0.040	0.960	0.000
T20.4 Corrosion of unspecified degree of head and neck	0.040	0.960	0.000
T20.3 Burn of third degree of head and neck	0.040	0.960	0.000
T20.0 Burn of unspecified degree of head and neck	0.039	0.960	0.000
T21.0 Burn of unspecified degree of trunk	0.039	0.961	0.000
T25.3 Burn of third degree of ankle and foot	0.039	0.961	0.000
T23.7 Corrosion of third degree of wrist and hand	0.038	0.961	0.000
T23.6 Corrosion of second degree of wrist and hand	0.038	0.961	0.000
T23.5 Corrosion of first degree of wrist and hand	0.038	0.961	0.000
T23.4 Corrosion of unspecified degree of wrist and hand	0.038	0.961	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.038	0.962	0.000
T21.7 Corrosion of third degree of trunk	0.037	0.962	0.000
T21.6 Corrosion of second degree of trunk	0.037	0.962	0.000
T21.5 Corrosion of first degree of trunk	0.037	0.962	0.000
T21.4 Corrosion of unspecified degree of trunk	0.037	0.962	0.000
T21.1 Burn of first degree of trunk	0.037	0.962	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.037	0.963	0.000
T23.1 Burn of first degree of wrist and hand	0.037	0.963	0.000
T25.2 Burn of second degree of ankle and foot	0.036	0.964	0.000
T25.7 Corrosion of third degree of ankle and foot	0.035	0.965	0.000
T25.6 Corrosion of second degree of ankle and foot	0.035	0.965	0.000
T25.5 Corrosion of first degree of ankle and foot	0.035	0.965	0.000
T25.4 Corrosion of unspecified degree of ankle and foot	0.035	0.965	0.000
T25.1 Burn of first degree of ankle and foot	0.035	0.965	0.000
T25.0 Burn of unspecified degree of ankle and foot	0.035	0.965	0.000
M72 Fibroblastic disorders	0.032	0.968	0.000
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.030	0.970	0.000
T21.3 Burn of third degree of trunk	0.029	0.971	0.000
T24.7 Corrosion of third degree of hip and lower limb, except ankle and foot	0.026	0.973	0.000
T24.6 Corrosion of second degree of hip and lower limb, except ankle and foot	0.026	0.973	0.000
T24.5 Corrosion of first degree of hip and lower limb, except ankle and foot	0.026	0.973	0.000
T24.4 Corrosion of unspecified degree of hip and lower limb, except ankle and foot	0.026	0.973	0.000
T24.1 Burn of first degree of hip and lower limb, except ankle and foot	0.026	0.973	0.000
M72.9 Fibroblastic disorder, unspecified	0.023	0.976	0.000
M72.8 Other fibroblastic disorders	0.023	0.976	0.000
M72.6 Necrotizing fasciitis	0.023	0.976	0.000
M72.5 Fasciitis, not elsewhere classified	0.023	0.976	0.000
M72.4 Pseudosarcomatous fibromatosis	0.023	0.976	0.000
M72.3 Nodular fasciitis	0.023	0.976	0.000
M72.1 Knuckle pads	0.023	0.976	0.000
M72.2 Plantar fascial fibromatosis	0.023	0.977	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.022	0.978	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.019	0.980	0.001
M72.29 Plantar fascial fibromatosis-Site unspec	0.018	0.982	0.000
M72.19 Knuckle pads (Site unspecified)	0.017	0.983	0.000
M72.18 Knuckle pads-Other	0.017	0.983	0.000
M72.17 Knuckle pads (Ankle and foot)	0.017	0.983	0.000
M72.16 Knuckle pads-Lower Leg	0.017	0.983	0.000
M72.15 Knuckle pads-Pelvic/Thigh	0.017	0.983	0.000
M72.14 Knuckle pads (Hand)	0.017	0.983	0.000
M72.13 Knuckle pads-Forearm	0.017	0.983	0.000
M72.12 Knuckle pads-Upper arm	0.017	0.983	0.000
M72.11 Knuckle pads-Shldr region	0.017	0.983	0.000
M72.10 Knuckle pads (Multiple sites)	0.017	0.983	0.000
M72.39 Nodular fasciitis-Site unspec	0.017	0.983	0.000
M72.38 Nodular fasciitis-Other	0.017	0.983	0.000
M72.37 Nodular fasciitis-Ankle/Foot	0.017	0.983	0.000
M72.36 Nodular fasciitis-Lower Leg	0.017	0.983	0.000
M72.35 Nodular fasciitis-Pelvic/Thigh	0.017	0.983	0.000
M72.34 Nodular fasciitis-Hand	0.017	0.983	0.000
M72.33 Nodular fasciitis-Forearm	0.017	0.983	0.000
M72.32 Nodular fasciitis-Upper arm	0.017	0.983	0.000
M72.31 Nodular fasciitis-Shldr region	0.017	0.983	0.000
M72.30 Nodular fasciitis-Mult sites	0.017	0.983	0.000
M72.49 Pseudosarcomatous fibromatosis (Site unspecified)	0.017	0.983	0.000
M72.48 Pseudosarcomatous fibromatosis (Other)	0.017	0.983	0.000
M72.47 Pseudosarcomatous fibromatosis (Ankle and foot)	0.017	0.983	0.000
M72.46 Pseudosarcomatous fibromatosis (Lower leg)	0.017	0.983	0.000
M72.45 Pseudosarcomatous fibromatosis (Pelvic region and thigh)	0.017	0.983	0.000
M72.44 Pseudosarcomatous fibromatosis (Hand)	0.017	0.983	0.000
M72.43 Pseudosarcomatous fibromatosis (Forearm)	0.017	0.983	0.000
M72.42 Pseudosarcomatous fibromatosis (Upper arm)	0.017	0.983	0.000
M72.41 Pseudosarcomatous fibromatosis (Shoulder region)	0.017	0.983	0.000
M72.40 Pseudosarcomatous fibromatosis (Multiple sites)	0.017	0.983	0.000
M72.59 Fasciitis, not elsewhere classified-Site unspec	0.017	0.983	0.000
M72.58 Fasciitis, not elsewhere classified-Other	0.017	0.983	0.000
M72.57 Fasciitis, not elsewhere classified-Ankle/Foot	0.017	0.983	0.000
M72.56 Fasciitis, not elsewhere classified-Lower Leg	0.017	0.983	0.000
M72.55 Fasciitis, not elsewhere classified-Pelvic/Thigh	0.017	0.983	0.000
M72.54 Fasciitis, not elsewhere classified-Hand	0.017	0.983	0.000
M72.53 Fasciitis, not elsewhere classified-Forearm	0.017	0.983	0.000
M72.52 Fasciitis, not elsewhere classified-Upper arm	0.017	0.983	0.000
M72.51 Fasciitis, not elsewhere classified-Shldr region	0.017	0.983	0.000
M72.50 Fasciitis, not elsewhere classified-Mult sites	0.017	0.983	0.000
M72.69 Necrotizing fasciitis (Site unspecified)	0.017	0.983	0.000
M72.68 Necrotizing fasciitis (Other)	0.017	0.983	0.000
M72.67 Necrotizing fasciitis (Ankle and foot)	0.017	0.983	0.000
M72.66 Necrotizing fasciitis (Lower leg)	0.017	0.983	0.000
M72.65 Necrotizing fasciitis (Pelvic region and thigh)	0.017	0.983	0.000
M72.64 Necrotizing fasciitis (Hand)	0.017	0.983	0.000
M72.63 Necrotizing fasciitis (Forearm)	0.017	0.983	0.000
M72.62 Necrotizing fasciitis (Upper arm)	0.017	0.983	0.000
M72.61 Necrotizing fasciitis (Shoulder region)	0.017	0.983	0.000
M72.60 Necrotizing fasciitis (Multiple sites)	0.017	0.983	0.000
M72.89 Other fibroblastic disorders (Site unspecified)	0.017	0.983	0.000
M72.88 Other fibroblastic disorders (Other)	0.017	0.983	0.000
M72.87 Other fibroblastic disorders (Ankle and foot)	0.017	0.983	0.000
M72.86 Other fibroblastic disorders (Lower leg)	0.017	0.983	0.000
M72.85 Other fibroblastic disorders (Pelvic region and thigh)	0.017	0.983	0.000
M72.84 Other fibroblastic disorders (Hand)	0.017	0.983	0.000
M72.83 Other fibroblastic disorders (Forearm)	0.017	0.983	0.000
M72.82 Other fibroblastic disorders (Upper arm)	0.017	0.983	0.000
M72.81 Other fibroblastic disorders (Shoulder region)	0.017	0.983	0.000
M72.80 Other fibroblastic disorders (Multiple sites)	0.017	0.983	0.000
M72.99 Fibroblastic disorder, unspecified (Site unspecified)	0.017	0.983	0.000
M72.98 Fibroblastic disorder, unspecified (Other)	0.017	0.983	0.000
M72.97 Fibroblastic disorder, unspecified (Ankle and foot)	0.017	0.983	0.000
M72.96 Fibroblastic disorder, unspecified (Lower leg)	0.017	0.983	0.000
M72.95 Fibroblastic disorder, unspecified (Pelvic region and thigh)	0.017	0.983	0.000
M72.94 Fibroblastic disorder, unspecified (Hand)	0.017	0.983	0.000
M72.93 Fibroblastic disorder, unspecified (Forearm)	0.017	0.983	0.000
M72.92 Fibroblastic disorder, unspecified (Upper arm)	0.017	0.983	0.000
M72.91 Fibroblastic disorder, unspecified (Shoulder region)	0.017	0.983	0.000
M72.90 Fibroblastic disorder, unspecified (Multiple sites)	0.017	0.983	0.000
M72.28 Plantar fascial fibromatosis-Other	0.016	0.983	0.000
M72.26 Plantar fascial fibromatosis-Lower Leg	0.016	0.983	0.000
M72.25 Plantar fascial fibromatosis-Pelvic/Thigh	0.016	0.983	0.000
M72.24 Plantar fascial fibromatosis-Hand	0.016	0.983	0.000
M72.23 Plantar fascial fibromatosis-Forearm	0.016	0.983	0.000
M72.22 Plantar fascial fibromatosis-Upper arm	0.016	0.983	0.000
M72.21 Plantar fascial fibromatosis-Shldr region	0.016	0.983	0.000
M72.20 Plantar fascial fibromatosis-Mult sites	0.016	0.983	0.000
D23.5 Skin of trunk	0.015	0.985	0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot	0.014	0.986	0.000
E78.5 Hyperlipidaemia, unspecified	0.000	0.987	0.013
H54.7 Unspecified visual loss	0.008	0.992	0.000
H21.8 Other specified disorders of iris and ciliary body	0.007	0.993	0.000
H54.9 Unspecified visual impairment (binocular)	0.007	0.993	0.000
H54 Blindness and low vision	0.007	0.993	0.000
H54.1 Blindness, one eye, low vision, other eye	0.006	0.994	0.000
H18.4 Corneal degeneration	0.006	0.994	0.000
H54.2 Low vision, both eyes	0.005	0.995	0.000
H54.6 Unqualified visual loss, one eye	0.005	0.995	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.005	0.995	0.000
H21 Other disorders of iris and ciliary body	0.005	0.995	0.000
H54.5 Low vision, one eye	0.005	0.995	0.000
H54.3 Unqualified visual loss, both eyes	0.005	0.995	0.000
Z13.9 Special screening examination, unspecified	0.000	0.995	0.005
H18.6 Keratoconus	0.005	0.995	0.000
H18.3 Changes in corneal membranes	0.005	0.995	0.000
H54.4 Blindness, one eye	0.004	0.996	0.000
S62.60 Fracture of other finger (closed)	0.004	0.996	0.000
H18.8 Other specified disorders of cornea	0.004	0.996	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
H18.2 Other corneal oedema	0.004	0.996	0.000
H16 Keratitis	0.004	0.996	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
H18.7 Other corneal deformities	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
H21.4 Pupillary membranes	0.004	0.996	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.004	0.996	0.000
H21.2 Degeneration of iris and ciliary body	0.004	0.996	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.004	0.996	0.000
F41.2 Mixed anxiety and depressive disorder	0.000	0.996	0.004
H21.5 Other adhesions and disruptions of iris and ciliary body	0.004	0.996	0.000
H18.9 Disorder of cornea, unspecified	0.004	0.996	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.004	0.996	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.004	0.996	0.000
N76.4 Abscess of vulva	0.004	0.996	0.000
S52.10 Fracture of upper end of radius (closed)	0.000	0.996	0.004
H16.0 Corneal ulcer	0.004	0.996	0.000
T31.0 Burns involving less than 10% of body surface	0.004	0.996	0.000
H21.0 Hyphaema	0.003	0.996	0.000
S82.20 Fracture of shaft of tibia (closed)	0.003	0.997	0.000
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
R06.5 Mouth breathing	0.000	0.997	0.003
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.997	0.000
D21.2 Connective and other soft tissue of lower limb, including hip	0.003	0.997	0.000
H16.4 Corneal neovascularisation	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
H16.8 Other keratitis	0.003	0.997	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
M19.04 Primary arthrosis of other joints (Hand)	0.003	0.997	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.003	0.997	0.000
Z83.7 Family history of diseases of the digestive system	0.000	0.997	0.003
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H15 Disorders of sclera	0.003	0.997	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
J38.0 Paralysis of vocal cords and larynx	0.003	0.997	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.997	0.003
N43.3 Hydrocele, unspecified	0.003	0.997	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.997	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
M84.05 Malunion of fracture (Pelvic region and thigh)	0.003	0.997	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.002	0.997	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.997	0.002
H25.0 Senile incipient cataract	0.003	0.997	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.998	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.998	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.000	0.998	0.002
T88.4 Failed or difficult intubation	0.002	0.998	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
M84.0 Malunion of fracture	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.998	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.002	0.998	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
H15.0 Scleritis	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
E78.3 Hyperchylomicronaemia	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
K51.9 Ulcerative colitis, unspecified	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
N48.6 Balanitis xerotica obliterans	0.002	0.998	0.000
R04.2 Haemoptysis	0.000	0.998	0.002
D21 Other benign neoplasms of connective and other soft tissue	0.002	0.998	0.000
T31 Burns classified according to extent of body surface involved	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
E78.6 Lipoprotein deficiency	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
E78.8 Other disorders of lipoprotein metabolism	0.000	0.998	0.002
H53-H54 Visual disturbances and blindness	0.002	0.998	0.000
H15.8 Other disorders of sclera	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.002	0.998	0.000
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
F60.9 Personality disorder, unspecified	0.002	0.998	0.000
S62.6 Fracture of other finger	0.002	0.998	0.000
H46 Optic neuritis	0.002	0.998	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.002	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.002	0.998	0.000
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
T88.9 Complication of surgical and medical care, unspecified	0.002	0.998	0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.002	0.998	0.000
T88.3 Malignant hyperthermia due to anaesthesis	0.002	0.998	0.000
T88.2 Shock due to anaesthesia	0.002	0.998	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.002	0.998	0.000
T88.0 Infection following immunisation	0.002	0.998	0.000
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.002	0.998	0.000
D21.0 Connective and other soft tissue of head, face and neck	0.002	0.998	0.000
I86.4 Gastric varices	0.002	0.998	0.000
S82.2 Fracture of shaft of tibia	0.002	0.998	0.000
J33.8 Other polyp of sinus	0.000	0.998	0.002
J38.2 Nodules of vocal cords	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
H44.2 Degenerative myopia	0.002	0.998	0.000
T88.5 Other complications of anaesthesia	0.002	0.998	0.000
D21.9 Connective and other soft tissue, unspecified	0.002	0.998	0.000
D41.0 Kidney	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.002	0.998	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.002	0.998	0.000
D21.6 Connective and other soft tissue of trunk, unspecified	0.002	0.998	0.000
D21.5 Connective and other soft tissue of pelvis	0.002	0.998	0.000
D21.4 Connective and other soft tissue of abdomen	0.002	0.998	0.000
D21.3 Connective and other soft tissue of thorax	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.001	0.998	0.000
O87.0 Superficial thrombophlebitis in the puerperium	0.002	0.998	0.000
T31.9 Burns involving 90% or more of body surface	0.002	0.998	0.000
T31.8 Burns involving 80-89% of body surface	0.002	0.998	0.000
T31.7 Burns involving 70-79% of body surface	0.002	0.998	0.000
T31.6 Burns involving 60-69% of body surface	0.002	0.998	0.000
T31.5 Burns involving 50-59% of body surface	0.002	0.998	0.000
T31.4 Burns involving 40-49% of body surface	0.002	0.998	0.000
T31.3 Burns involving 30-39% of body surface	0.002	0.998	0.000
T31.2 Burns involving 20-29% of body surface	0.002	0.998	0.000
T31.1 Burns involving 10-19% of body surface	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.998	0.002
E78.4 Other hyperlipidaemia	0.000	0.998	0.002
J10.1 Influenza with other respiratory manifestations, influenza virus identified	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.000	0.998	0.002
M85.6 Other cyst of bone	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
M84.03 Malunion of fracture (Forearm)	0.002	0.998	0.000
E27.4 Other and unspecified adrenocortical insufficiency	0.002	0.998	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.998	0.002
H47 Other disorders of optic [2nd] nerve and visual pathways	0.002	0.998	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.002	0.998	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.002	0.998	0.000
M85.20 Hyperostosis of skull-Mult sites	0.002	0.998	0.000
C49.1 Connective and soft tissue of upper limb, including shoulder	0.002	0.998	0.000
H47.3 Other disorders of optic disk	0.002	0.998	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
M85.64 Other cyst of bone (Hand)	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.002	0.998	0.000
H04.1 Other disorders of lachrymal gland	0.002	0.998	0.000
H52.2 Astigmatism	0.002	0.998	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.002	0.998	0.000
C66 Malignant neoplasm of ureter	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
M85.2 Hyperostosis of skull	0.002	0.998	0.000
S82.21 Fracture of shaft of tibia (open)	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.002	0.998	0.000
M84 Disorders of continuity of bone	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.002	0.998	0.000
M85 Other disorders of bone density and structure	0.002	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.001	0.998	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.001	0.998	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.001	0.998	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.001	0.998	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.998	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.001	0.998	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.001	0.998	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.001	0.998	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.001	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.998	0.002
H26.8 Other specified cataract	0.000	0.998	0.002
J38.3 Other diseases of vocal cords	0.002	0.998	0.000
K56.6 Other and unspecified intestinal obstruction	0.002	0.998	0.000
S52.11 Fracture of upper end of radius (open)	0.000	0.998	0.001
D86.8 Sarcoidosis of other and combined sites	0.001	0.998	0.000
G82.2 Paraplegia, unspecified	0.002	0.998	0.000
S22.0 Fracture of thoracic vertebra	0.002	0.998	0.000
H20 Iridocyclitis	0.001	0.998	0.000
M85.69 Other cyst of bone (Site unspecified)	0.001	0.998	0.000
M85.68 Other cyst of bone (Other)	0.001	0.998	0.000
M85.66 Other cyst of bone (Lower leg)	0.001	0.998	0.000
M85.63 Other cyst of bone (Forearm)	0.001	0.998	0.000
M85.62 Other cyst of bone (Upper arm)	0.001	0.998	0.000
M85.61 Other cyst of bone (Shoulder region)	0.001	0.998	0.000
M85.60 Other cyst of bone (Multiple sites)	0.001	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.001	0.998	0.000
N20.2 Calculus of kidney with calculus of ureter	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.998	0.001
H47.7 Disorder of visual pathways, unspecified	0.001	0.998	0.000
H47.6 Disorders of visual cortex	0.001	0.998	0.000
H47.5 Disorders of other visual pathways	0.001	0.998	0.000
H47.4 Disorders of optic chiasm	0.001	0.998	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.001	0.998	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
F60.0 Paranoid personality disorder	0.001	0.998	0.000
V23.4 Driver injured in traffic accident	0.001	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
Z43.1 Attention to gastrostomy	0.001	0.999	0.000
F60 Specific personality disorders	0.001	0.999	0.000
M84.4 Pathological fracture, not elsewhere classified	0.001	0.999	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.999	0.001
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.001	0.999	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.001	0.999	0.000
M84.88 Other disorders of continuity of bone (Other)	0.001	0.999	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.001	0.999	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.001	0.999	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.001	0.999	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.001	0.999	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.001	0.999	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.001	0.999	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.001	0.999	0.000
M85.29 Hyperostosis of skull-Site unspec	0.001	0.999	0.000
M85.28 Hyperostosis of skull-Other	0.001	0.999	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.001	0.999	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.001	0.999	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.001	0.999	0.000
M85.24 Hyperostosis of skull-Hand	0.001	0.999	0.000
M85.23 Hyperostosis of skull-Forearm	0.001	0.999	0.000
M85.22 Hyperostosis of skull-Upper arm	0.001	0.999	0.000
M85.21 Hyperostosis of skull-Shldr region	0.001	0.999	0.000
S62.61 Fracture of other finger (open)	0.001	0.999	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.001	0.999	0.000
H10.4 Chronic conjunctivitis	0.001	0.999	0.000
H81.0 Meniere's disease	0.000	0.999	0.001
M80.8 Other osteoporosis with pathological fracture	0.001	0.999	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.001	0.999	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.001	0.999	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.001	0.999	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.001	0.999	0.000
F25.1 Schizoaffective disorder, depressive type	0.001	0.999	0.000
M50.3 Other cervical disk degeneration	0.000	0.999	0.001
M84.9 Disorder of continuity of bone, unspecified	0.001	0.999	0.000
M84.3 Stress fracture, not elsewhere classified	0.001	0.999	0.000
M84.2 Delayed union of fracture	0.001	0.999	0.000
D80 Immunodeficiency with predominantly antibody defects	0.001	0.999	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
H47.2 Optic atrophy	0.001	0.999	0.000
M85.9 Disorder of bone density and structure, unspecified	0.001	0.999	0.000
M85.5 Aneurysmal bone cyst	0.001	0.999	0.000
M85.4 Solitary bone cyst	0.001	0.999	0.000
M85.3 Osteitis condensans	0.001	0.999	0.000
M85.1 Skeletal fluorosis	0.001	0.999	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.001	0.999	0.000
S22.01 Fracture of thoracic vertebra (open)	0.001	0.999	0.000
C49.9 Connective and soft tissue, unspecified	0.001	0.999	0.000
H20.2 Lens-induced iridocyclitis	0.001	0.999	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.999	0.001
Q66.8 Other congenital deformities of feet	0.001	0.999	0.000
M24.56 Contracture of joint (Lower leg)	0.001	0.999	0.000
D84.1 Defects in the complement system	0.001	0.999	0.000
F60.6 Anxious [avoidant] personality disorder	0.001	0.999	0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.001	0.999	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.001	0.999	0.000
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
H47.1 Papilloedema, unspecified	0.001	0.999	0.000
Q12.0 Congenital cataract	0.001	0.999	0.000
S12.7 Multiple fractures of cervical spine	0.001	0.999	0.000
B25.9 Cytomegaloviral disease, unspecified	0.001	0.999	0.000
C49.5 Connective and soft tissue of pelvis	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
F60.5 Anankastic personality disorder	0.001	0.999	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.001	0.999	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.001	0.999	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.001	0.999	0.000
M85.0 Fibrous dysplasia (monostotic)	0.001	0.999	0.000
F25 Schizoaffective disorders	0.001	0.999	0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.001	0.999	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.001	0.999	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.001	0.999	0.000
F60.8 Other specific personality disorders	0.001	0.999	0.000
F60.7 Dependent personality disorder	0.001	0.999	0.000
F60.4 Histrionic personality disorder	0.001	0.999	0.000
F60.2 Dissocial personality disorder	0.001	0.999	0.000
F60.1 Schizoid personality disorder	0.001	0.999	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.001	0.999	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.001	0.999	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.001	0.999	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.001	0.999	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.001	0.999	0.000
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
C49.6 Connective and soft tissue of trunk, unspecified	0.001	0.999	0.000
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
H52.0 Hypermetropia	0.001	0.999	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.001	0.999	0.000
R68.8 Other specified general symptoms and signs	0.001	0.999	0.000
M80-M85 Disorders of bone density and structure	0.001	0.999	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.001	0.999	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.001	0.999	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.001	0.999	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.001	0.999	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.001	0.999	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.001	0.999	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.001	0.999	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.001	0.999	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.001	0.999	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.001	0.999	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.001	0.999	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.001	0.999	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations