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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11752643
log Bayes Factor = 13.3291
Chromosome 6   position 32,669,373  (GRCh37) Explore rs11752643 on Ensembl!
Variant rs11752643 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.037 0.963
E00-E07 Disorders of thyroid gland
0.000 0.063 0.937
J45 Asthma
0.000 0.064 0.936
K29 Gastritis and duodenitis
0.000 0.072 0.928
K29.8 Duodenitis
0.000 0.072 0.928
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.074 0.926
K90.0 Coeliac disease
0.000 0.083 0.917
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.097 0.903
J40-J47 Chronic lower respiratory diseases
0.000 0.102 0.898
K26 Duodenal ulcer
0.000 0.108 0.892
J44 Other chronic obstructive pulmonary disease
0.000 0.115 0.885
K29.5 Chronic gastritis, unspecified
0.000 0.123 0.877
K90 Intestinal malabsorption
0.000 0.132 0.868
E05.9 Thyrotoxicosis, unspecified
0.000 0.141 0.859
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.143 0.857
K90-K93 Other diseases of the digestive system
0.000 0.160 0.840
J44.9 Chronic obstructive pulmonary disease, unspecified
0.000 0.169 0.831
Chapter XI Diseases of the digestive system
0.000 0.171 0.828
K30 Dyspepsia
0.000 0.181 0.819
K29.4 Chronic atrophic gastritis
0.000 0.183 0.817
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.000 0.190 0.810
Chapter X Diseases of the respiratory system
0.002 0.197 0.801
K25 Gastric ulcer
0.000 0.203 0.797
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.209 0.791
K22 Other diseases of oesophagus
0.000 0.219 0.781
Chapter IV Endocrine, nutritional and metabolic diseases
0.005 0.231 0.764
J44.8 Other specified chronic obstructive pulmonary disease
0.000 0.232 0.768
J20-J22 Other acute lower respiratory infections
0.001 0.239 0.761
K20 Oesophagitis
0.000 0.250 0.750
K26.4 Chronic or unspecified with haemorrhage
0.000 0.253 0.747
E06 Thyroiditis
0.000 0.254 0.746
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.256 0.744
J22 Unspecified acute lower respiratory infection
0.000 0.267 0.733
E20-E35 Disorders of other endocrine glands
0.002 0.269 0.728
K27 Peptic ulcer, site unspecified
0.000 0.276 0.723
K29.1 Other acute gastritis
0.000 0.278 0.722
J00-J06 Acute upper respiratory infections
0.001 0.281 0.718
E07 Other disorders of thyroid
0.000 0.286 0.714
K70-K77 Diseases of liver
0.000 0.286 0.714
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.001 0.291 0.708
K22.2 Oesophageal obstruction
0.000 0.303 0.697
E03.8 Other specified hypothyroidism
0.000 0.309 0.690
E03.5 Myxoedema coma
0.000 0.309 0.690
E03.4 Atrophy of thyroid (acquired)
0.000 0.309 0.690
E03.3 Postinfectious hypothyroidism
0.000 0.309 0.690
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.309 0.690
E03.1 Congenital hypothyroidism without goitre
0.000 0.309 0.690
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.309 0.690
J95-J99 Other diseases of the respiratory system
0.001 0.315 0.684
E50-E64 Other nutritional deficiencies
0.003 0.318 0.680
K22.1 Ulcer of oesophagus
0.000 0.323 0.677
K29.3 Chronic superficial gastritis
0.000 0.328 0.672
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.328 0.671
E00 Congenital iodine-deficiency syndrome
0.000 0.328 0.671
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.328 0.671
J45.8 Mixed asthma
0.000 0.329 0.671
J45.1 Nonallergic asthma
0.000 0.329 0.671
K29.9 Gastroduodenitis, unspecified
0.000 0.334 0.665
K29.2 Alcoholic gastritis
0.000 0.334 0.665
K28 Gastrojejunal ulcer
0.000 0.336 0.664
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.336 0.664
E21.0 Primary hyperparathyroidism
0.000 0.337 0.662
K22.9 Disease of oesophagus, unspecified
0.000 0.339 0.661
K25.3 Acute without haemorrhage or perforation
0.000 0.346 0.654
E05.8 Other thyrotoxicosis
0.000 0.353 0.647
E05.5 Thyroid crisis or storm
0.000 0.353 0.647
E05.4 Thyrotoxicosis factitia
0.000 0.353 0.647
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.353 0.647
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.353 0.647
E21.3 Hyperparathyroidism, unspecified
0.000 0.354 0.646
J41 Simple and mucopurulent chronic bronchitis
0.000 0.356 0.644
J46 Status asthmaticus
0.000 0.356 0.644
K26.7 Chronic without haemorrhage or perforation
0.000 0.360 0.640
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.361 0.639
K26.5 Chronic or unspecified with perforation
0.000 0.361 0.639
K26.2 Acute with both haemorrhage and perforation
0.000 0.361 0.639
K26.1 Acute with perforation
0.000 0.361 0.639
K26.0 Acute with haemorrhage
0.000 0.361 0.639
J02 Acute pharyngitis
0.000 0.368 0.631
J42 Unspecified chronic bronchitis
0.000 0.372 0.628
K90.8 Other intestinal malabsorption
0.000 0.378 0.622
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.378 0.622
K90.3 Pancreatic steatorrhoea
0.000 0.378 0.622
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.378 0.622
K90.1 Tropical sprue
0.000 0.378 0.622
J45.0 Predominantly allergic asthma
0.000 0.379 0.621
K31 Other diseases of stomach and duodenum
0.000 0.381 0.619
K92 Other diseases of digestive system
0.000 0.382 0.618
J90-J94 Other diseases of pleura
0.001 0.385 0.614
E06.3 Autoimmune thyroiditis
0.000 0.391 0.609
J06 Acute upper respiratory infections of multiple and unspecified sites
0.000 0.392 0.608
K22.8 Other specified diseases of oesophagus
0.000 0.393 0.607
E55 Vitamin D deficiency
0.001 0.396 0.603
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.398 0.602
K76 Other diseases of liver
0.000 0.399 0.601
# Top node
0.044 0.399 0.557
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.001 0.410 0.589
K29.0 Acute haemorrhagic gastritis
0.000 0.415 0.585
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.422 0.578
K26.3 Acute without haemorrhage or perforation
0.000 0.424 0.576
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.428 0.572
K25.5 Chronic or unspecified with perforation
0.000 0.428 0.572
K25.2 Acute with both haemorrhage and perforation
0.000 0.428 0.572
K25.1 Acute with perforation
0.000 0.428 0.572
K25.0 Acute with haemorrhage
0.000 0.428 0.572
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.429 0.571
J02.9 Acute pharyngitis, unspecified
0.000 0.430 0.570
K70 Alcoholic liver disease
0.000 0.432 0.568
J95 Postprocedural respiratory disorders, not elsewhere classified
0.001 0.432 0.567
K72 Hepatic failure, not elsewhere classified
0.000 0.433 0.567
O60-O75 Complications of labour and delivery
0.565 0.435 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.558 0.440 0.003
K22.3 Perforation of oesophagus
0.000 0.440 0.560
K90.9 Intestinal malabsorption, unspecified
0.000 0.442 0.558
E04 Other non-toxic goitre
0.000 0.443 0.557
K22.4 Dyskinesia of oesophagus
0.000 0.443 0.557
E07.9 Disorder of thyroid, unspecified
0.000 0.445 0.554
K76.9 Liver disease, unspecified
0.000 0.446 0.554
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.000 0.448 0.552
E55.9 Vitamin D deficiency, unspecified
0.001 0.452 0.548
J21 Acute bronchiolitis
0.001 0.454 0.545
K35-K38 Diseases of appendix
0.000 0.454 0.546
J98 Other respiratory disorders
0.000 0.454 0.545
E29 Testicular dysfunction
0.002 0.463 0.535
J20 Acute bronchitis
0.001 0.463 0.536
K22.5 Diverticulum of oesophagus, acquired
0.000 0.464 0.536
E06.9 Thyroiditis, unspecified
0.000 0.465 0.535
E06.5 Other chronic thyroiditis
0.000 0.465 0.535
E06.4 Drug-induced thyroiditis
0.000 0.465 0.535
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.465 0.535
E06.1 Subacute thyroiditis
0.000 0.465 0.535
E06.0 Acute thyroiditis
0.000 0.465 0.535
E53 Deficiency of other B group vitamins
0.002 0.467 0.531
K92.1 Melaena
0.000 0.467 0.532
J06.9 Acute upper respiratory infection, unspecified
0.000 0.471 0.529
E23 Hypofunction and other disorders of pituitary gland
0.002 0.471 0.527
K65-K67 Diseases of peritoneum
0.000 0.472 0.528
J90 Pleural effusion, not elsewhere classified
0.000 0.472 0.527
O68 Labour and delivery complicated by foetal stress [distress]
0.527 0.473 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.002 0.476 0.522
E34 Other endocrine disorders
0.002 0.476 0.522
E32 Diseases of thymus
0.002 0.476 0.522
E31 Polyglandular dysfunction
0.002 0.476 0.522
E30 Disorders of puberty, not elsewhere classified
0.002 0.476 0.522
E26 Hyperaldosteronism
0.002 0.476 0.522
E25 Adrenogenital disorders
0.002 0.476 0.522
E24 Cushing's syndrome
0.002 0.476 0.522
E20 Hypoparathyroidism
0.002 0.476 0.522
J43 Emphysema
0.000 0.480 0.519
K27.7 Chronic without haemorrhage or perforation
0.000 0.481 0.519
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.481 0.519
K27.5 Chronic or unspecified with perforation
0.000 0.481 0.519
K27.4 Chronic or unspecified with haemorrhage
0.000 0.481 0.519
K27.3 Acute without haemorrhage or perforation
0.000 0.481 0.519
K27.2 Acute with both haemorrhage and perforation
0.000 0.481 0.519
K27.1 Acute with perforation
0.000 0.481 0.519
K27.0 Acute with haemorrhage
0.000 0.481 0.519
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.001 0.485 0.515
J04 Acute laryngitis and tracheitis
0.001 0.485 0.515
J01 Acute sinusitis
0.001 0.485 0.515
J60-J70 Lung diseases due to external agents
0.002 0.486 0.513
E07.8 Other specified disorders of thyroid
0.000 0.488 0.512
E07.1 Dyshormogenetic goitre
0.000 0.488 0.512
E07.0 Hypersecretion of calcitonin
0.000 0.488 0.512
K77 Liver disorders in diseases classified elsewhere
0.000 0.488 0.512
K73 Chronic hepatitis, not elsewhere classified
0.000 0.488 0.512
K71 Toxic liver disease
0.000 0.488 0.512
E28 Ovarian dysfunction
0.002 0.489 0.509
O62 Abnormalities of forces of labour
0.511 0.489 0.000
K22.0 Achalasia of cardia
0.000 0.490 0.510
E21.5 Disorder of parathyroid gland, unspecified
0.001 0.491 0.508
E21.4 Other specified disorders of parathyroid gland
0.001 0.491 0.508
E21.2 Other hyperparathyroidism
0.001 0.491 0.508
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.001 0.491 0.508
E27 Other disorders of adrenal gland
0.002 0.493 0.505
K92.0 Haematemesis
0.000 0.495 0.505
O69 Labour and delivery complicated by umbilical cord complications
0.502 0.498 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.004 0.501 0.496
O94-O99 Other obstetric conditions, not elsewhere classified
0.496 0.503 0.001
J98.1 Pulmonary collapse
0.000 0.506 0.494
K31.7 Polyp of stomach and duodenum
0.000 0.506 0.494
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.492 0.507 0.000
J03 Acute tonsillitis
0.001 0.508 0.492
O80-O84 Delivery
0.491 0.508 0.002
K70.9 Alcoholic liver disease, unspecified
0.000 0.508 0.492
J99 Respiratory disorders in diseases classified elsewhere
0.001 0.509 0.490
J96 Respiratory failure, not elsewhere classified
0.001 0.509 0.490
O72 Postpartum haemorrhage
0.491 0.509 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.002 0.511 0.487
E63 Other nutritional deficiencies
0.002 0.511 0.487
E56 Other vitamin deficiencies
0.002 0.511 0.487
E51 Thiamine deficiency
0.002 0.511 0.487
E50 Vitamin A deficiency
0.002 0.511 0.487
E60 Dietary zinc deficiency
0.002 0.511 0.487
E59 Dietary selenium deficiency
0.002 0.511 0.487
E58 Dietary calcium deficiency
0.002 0.511 0.487
E54 Ascorbic acid deficiency
0.002 0.511 0.487
E52 Niacin deficiency [pellagra]
0.002 0.511 0.487
K76.6 Portal hypertension
0.000 0.511 0.489
O64 Obstructed labour due to malposition and malpresentation of foetus
0.488 0.512 0.000
J00 Acute nasopharyngitis [common cold]
0.001 0.513 0.487
E61 Deficiency of other nutrient elements
0.002 0.513 0.485
O20-O29 Other maternal disorders predominantly related to pregnancy
0.483 0.516 0.001
J95.8 Other postprocedural respiratory disorders
0.000 0.516 0.484
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.518 0.481
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.518 0.481
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.518 0.481
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.518 0.481
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.518 0.481
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.518 0.481
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.518 0.481
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.518 0.481
E22 Hyperfunction of pituitary gland
0.002 0.521 0.477
K75 Other inflammatory liver diseases
0.000 0.521 0.479
E40-E46 Malnutrition
0.005 0.523 0.473
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.524 0.476
K23.1 Megaoesophagus in Chagas' disease
0.000 0.524 0.476
K23.0 Tuberculous oesophagitis
0.000 0.524 0.476
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.524 0.476
K28.7 Chronic without haemorrhage or perforation
0.000 0.524 0.476
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.524 0.476
K28.5 Chronic or unspecified with perforation
0.000 0.524 0.476
K28.4 Chronic or unspecified with haemorrhage
0.000 0.524 0.476
K28.3 Acute without haemorrhage or perforation
0.000 0.524 0.476
K28.2 Acute with both haemorrhage and perforation
0.000 0.524 0.476
K28.1 Acute with perforation
0.000 0.524 0.476
K28.0 Acute with haemorrhage
0.000 0.524 0.476
K74 Fibrosis and cirrhosis of liver
0.000 0.527 0.472
J92 Pleural plaque
0.000 0.530 0.470
O63 Long labour
0.469 0.531 0.000
O00-O08 Pregnancy with abortive outcome
0.467 0.532 0.001
J40 Bronchitis, not specified as acute or chronic
0.000 0.535 0.464
O82 Single delivery by Caesarean section
0.463 0.537 0.001
K72.9 Hepatic failure, unspecified
0.000 0.538 0.462
K25.4 Chronic or unspecified with haemorrhage
0.000 0.538 0.462
J41.8 Mixed simple and mucopurulent chronic bronchitis
0.000 0.538 0.462
J41.1 Mucopurulent chronic bronchitis
0.000 0.538 0.462
J41.0 Simple chronic bronchitis
0.000 0.538 0.462
O69.1 Labour and delivery complicated by cord around neck, with compression
0.459 0.541 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.454 0.546 0.000
J02.8 Acute pharyngitis due to other specified organisms
0.000 0.547 0.453
J02.0 Streptococcal pharyngitis
0.000 0.547 0.453
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.453 0.547 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.452 0.548 0.001
O40 Polyhydramnios
0.448 0.552 0.000
O62.3 Precipitate labour
0.447 0.553 0.000
K31.6 Fistula of stomach and duodenum
0.000 0.556 0.444
K31.5 Obstruction of duodenum
0.000 0.556 0.444
K31.3 Pylorospasm, not elsewhere classified
0.000 0.556 0.444
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.556 0.444
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.556 0.444
K31.0 Acute dilatation of stomach
0.000 0.556 0.444
K92.8 Other specified diseases of digestive system
0.000 0.557 0.443
J94 Other pleural conditions
0.001 0.559 0.441
K92.9 Disease of digestive system, unspecified
0.000 0.561 0.439
Chapter XXII Codes for special purposes
0.030 0.562 0.408
J86 Pyothorax
0.001 0.562 0.437
J80-J84 Other respiratory diseases principally affecting the interstitium
0.002 0.563 0.436
E04.9 Non-toxic goitre, unspecified
0.000 0.563 0.437
J06.8 Other acute upper respiratory infections of multiple sites
0.000 0.564 0.436
J06.0 Acute laryngopharyngitis
0.000 0.564 0.436
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.435 0.565 0.000
O72.1 Other immediate postpartum haemorrhage
0.435 0.565 0.000
O63.0 Prolonged first stage (of labour)
0.435 0.565 0.000
E55.0 Rickets, active
0.001 0.567 0.432
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.568 0.432
K93.1 Megacolon in Chagas' disease
0.000 0.568 0.432
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.568 0.432
K76.7 Hepatorenal syndrome
0.000 0.569 0.431
K76.5 Hepatic veno-occlusive disease
0.000 0.569 0.431
K76.4 Peliosis hepatis
0.000 0.569 0.431
K76.3 Infarction of liver
0.000 0.569 0.431
K76.2 Central haemorrhagic necrosis of liver
0.000 0.569 0.431
K76.1 Chronic passive congestion of liver
0.000 0.569 0.431
Chapter XVI Certain conditions originating in the perinatal period
0.032 0.569 0.399
O26 Maternal care for other conditions predominantly related to pregnancy
0.429 0.570 0.000
O64.1 Obstructed labour due to breech presentation
0.429 0.571 0.000
O73 Retained placenta and membranes, without haemorrhage
0.429 0.571 0.000
E53.8 Deficiency of other specified B group vitamins
0.001 0.575 0.424
J85 Abscess of lung and mediastinum
0.001 0.577 0.422
K31.8 Other specified diseases of stomach and duodenum
0.000 0.578 0.422
O82.0 Delivery by elective Caesarean section
0.420 0.579 0.000
J09-J18 Influenza and pneumonia
0.001 0.584 0.415
K31.4 Gastric diverticulum
0.000 0.588 0.412
J47 Bronchiectasis
0.000 0.588 0.412
O62.0 Primary inadequate contractions
0.411 0.589 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.000 0.590 0.410
K70.4 Alcoholic hepatic failure
0.000 0.592 0.407
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.592 0.407
K70.0 Alcoholic fatty liver
0.000 0.592 0.407
E23.0 Hypopituitarism
0.001 0.593 0.406
J95.9 Postprocedural respiratory disorder, unspecified
0.001 0.593 0.407
J95.5 Postprocedural subglottic stenosis
0.001 0.593 0.407
J95.4 Mendelson's syndrome
0.001 0.593 0.407
J95.3 Chronic pulmonary insufficiency following surgery
0.001 0.593 0.407
J95.2 Acute pulmonary insufficiency following nonthoracic surgery
0.001 0.593 0.407
J95.1 Acute pulmonary insufficiency following thoracic surgery
0.001 0.593 0.407
J95.0 Tracheostomy malfunction
0.001 0.593 0.407
K72.1 Chronic hepatic failure
0.000 0.593 0.407
K72.0 Acute and subacute hepatic failure
0.000 0.593 0.407
J91 Pleural effusion in conditions classified elsewhere
0.001 0.594 0.405
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.595 0.405
O74 Complications of anaesthesia during labour and delivery
0.405 0.595 0.000
O71 Other obstetric trauma
0.405 0.595 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.405 0.595 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.405 0.595 0.000
O61 Failed induction of labour
0.405 0.595 0.000
O60 Preterm delivery
0.405 0.595 0.000
K35 Acute appendicitis
0.000 0.597 0.403
O85-O92 Complications predominantly related to the puerperium
0.400 0.598 0.002
E04.8 Other specified non-toxic goitre
0.000 0.600 0.399
E04.0 Non-toxic diffuse goitre
0.000 0.600 0.399
O82.1 Delivery by emergency Caesarean section
0.399 0.601 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.399 0.601 0.000
E29.1 Testicular hypofunction
0.001 0.602 0.397
J98.8 Other specified respiratory disorders
0.000 0.605 0.394
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.000 0.606 0.394
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.392 0.608 0.000
J21.9 Acute bronchiolitis, unspecified
0.001 0.608 0.391
J21.8 Acute bronchiolitis due to other specified organisms
0.001 0.608 0.391
J21.1 Acute bronchiolitis due to human metapneumovirus
0.001 0.608 0.391
J21.0 Acute bronchiolitis due to respiratory syncytial virus
0.001 0.608 0.391
O30 Multiple gestation
0.391 0.608 0.000
J98.6 Disorders of diaphragm
0.000 0.609 0.391
J98.5 Diseases of mediastinum, not elsewhere classified
0.000 0.609 0.391
J98.3 Compensatory emphysema
0.000 0.609 0.391
J98.2 Interstitial emphysema
0.000 0.609 0.391
K36 Other appendicitis
0.000 0.609 0.391
O72.2 Delayed and secondary postpartum haemorrhage
0.391 0.609 0.000
K50-K52 Noninfective enteritis and colitis
0.007 0.610 0.383
K38 Other diseases of appendix
0.000 0.612 0.388
O75 Other complications of labour and delivery, not elsewhere classified
0.388 0.612 0.000
K70.3 Alcoholic cirrhosis of liver
0.000 0.612 0.387
K25.7 Chronic without haemorrhage or perforation
0.001 0.615 0.385
E29.9 Testicular dysfunction, unspecified
0.001 0.615 0.384
E29.8 Other testicular dysfunction
0.001 0.615 0.384
E29.0 Testicular hyperfunction
0.001 0.615 0.384
J20.8 Acute bronchitis due to other specified organisms
0.001 0.615 0.384
J20.7 Acute bronchitis due to echovirus
0.001 0.615 0.384
J20.6 Acute bronchitis due to rhinovirus
0.001 0.615 0.384
J20.5 Acute bronchitis due to respiratory syncytial virus
0.001 0.615 0.384
J20.4 Acute bronchitis due to parainfluenza virus
0.001 0.615 0.384
J20.3 Acute bronchitis due to coxsackie virus
0.001 0.615 0.384
J20.2 Acute bronchitis due to streptococcus
0.001 0.615 0.384
J20.1 Acute bronchitis due to Haemophilus influenzae
0.001 0.615 0.384
J20.0 Acute bronchitis due to Mycoplasma pneumoniae
0.001 0.615 0.384
O62.2 Other uterine inertia
0.385 0.615 0.000
O42 Premature rupture of membranes
0.385 0.615 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.616 0.384
O26.8 Other specified pregnancy-related conditions
0.382 0.618 0.000
O66 Other obstructed labour
0.382 0.618 0.000
E53.9 Vitamin B deficiency, unspecified
0.001 0.618 0.381
E53.1 Pyridoxine deficiency
0.001 0.618 0.381
E53.0 Riboflavin deficiency
0.001 0.618 0.381
E23.7 Disorder of pituitary gland, unspecified
0.001 0.621 0.378
E23.6 Other disorders of pituitary gland
0.001 0.621 0.378
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.001 0.621 0.378
E23.1 Drug-induced hypopituitarism
0.001 0.621 0.378
O35 Maternal care for known or suspected foetal abnormality and damage
0.379 0.621 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.621 0.378
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.378 0.622 0.000
E70-E90 Metabolic disorders
0.001 0.623 0.376
E65-E68 Obesity and other hyperalimentation
0.004 0.624 0.372
E20.9 Hypoparathyroidism, unspecified
0.001 0.624 0.374
E20.8 Other hypoparathyroidism
0.001 0.624 0.374
E20.1 Pseudohypoparathyroidism
0.001 0.624 0.374
E20.0 Idiopathic hypoparathyroidism
0.001 0.624 0.374
E24.9 Cushing's syndrome, unspecified
0.001 0.624 0.374
E24.8 Other Cushing's syndrome
0.001 0.624 0.374
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.001 0.624 0.374
E24.3 Ectopic ACTH syndrome
0.001 0.624 0.374
E24.2 Drug-induced Cushing's syndrome
0.001 0.624 0.374
E24.1 Nelson's syndrome
0.001 0.624 0.374
E24.0 Pituitary-dependent Cushing's disease
0.001 0.624 0.374
E25.9 Adrenogenital disorder, unspecified
0.001 0.624 0.374
E25.8 Other adrenogenital disorders
0.001 0.624 0.374
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.001 0.624 0.374
E26.9 Hyperaldosteronism, unspecified
0.001 0.624 0.374
E26.8 Other hyperaldosteronism
0.001 0.624 0.374
E26.1 Secondary hyperaldosteronism
0.001 0.624 0.374
E26.0 Primary hyperaldosteronism
0.001 0.624 0.374
E30.9 Disorder of puberty, unspecified
0.001 0.624 0.374
E30.8 Other disorders of puberty
0.001 0.624 0.374
E30.1 Precocious puberty
0.001 0.624 0.374
E30.0 Delayed puberty
0.001 0.624 0.374
E31.9 Polyglandular dysfunction, unspecified
0.001 0.624 0.374
E31.8 Other polyglandular dysfunction
0.001 0.624 0.374
E31.1 Polyglandular hyperfunction
0.001 0.624 0.374
E31.0 Autoimmune polyglandular failure
0.001 0.624 0.374
E32.9 Disease of thymus, unspecified
0.001 0.624 0.374
E32.8 Other diseases of thymus
0.001 0.624 0.374
E32.1 Abscess of thymus
0.001 0.624 0.374
E32.0 Persistent hyperplasia of thymus
0.001 0.624 0.374
E34.9 Endocrine disorder, unspecified
0.001 0.624 0.374
E34.8 Other specified endocrine disorders
0.001 0.624 0.374
E34.5 Androgen resistance syndrome
0.001 0.624 0.374
E34.4 Constitutional tall stature
0.001 0.624 0.374
E34.3 Short stature, not elsewhere classified
0.001 0.624 0.374
E34.2 Ectopic hormone secretion, not elsewhere classified
0.001 0.624 0.374
E34.1 Other hypersecretion of intestinal hormones
0.001 0.624 0.374
E34.0 Carcinoid syndrome
0.001 0.624 0.374
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.001 0.624 0.374
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.001 0.624 0.374
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.001 0.624 0.374
J92.9 Pleural plaque without asbestos
0.000 0.624 0.375
J20.9 Acute bronchitis, unspecified
0.001 0.624 0.375
O03 Spontaneous abortion
0.375 0.624 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.375 0.625 0.000
O04 Medical abortion
0.373 0.627 0.000
K65 Peritonitis
0.000 0.627 0.373
J43.8 Other emphysema
0.000 0.627 0.372
J43.2 Centrilobular emphysema
0.000 0.627 0.372
J43.1 Panlobular emphysema
0.000 0.627 0.372
J43.0 MacLeod's syndrome
0.000 0.627 0.372
E10-E14 Diabetes mellitus
0.005 0.627 0.368
O43 Placental disorders
0.372 0.627 0.000
K70.1 Alcoholic hepatitis
0.000 0.628 0.372
J01.9 Acute sinusitis, unspecified
0.001 0.630 0.369
J01.8 Other acute sinusitis
0.001 0.630 0.369
J01.4 Acute pansinusitis
0.001 0.630 0.369
J01.3 Acute sphenoidal sinusitis
0.001 0.630 0.369
J01.2 Acute ethmoidal sinusitis
0.001 0.630 0.369
J01.1 Acute frontal sinusitis
0.001 0.630 0.369
J01.0 Acute maxillary sinusitis
0.001 0.630 0.369
J04.2 Acute laryngotracheitis
0.001 0.630 0.369
J04.1 Acute tracheitis
0.001 0.630 0.369
J04.0 Acute laryngitis
0.001 0.630 0.369
J05.1 Acute epiglottitis
0.001 0.630 0.369
J05.0 Acute obstructive laryngitis [croup]
0.001 0.630 0.369
J70 Respiratory conditions due to other external agents
0.001 0.631 0.368
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.001 0.631 0.368
J67 Hypersensitivity pneumonitis due to organic dust
0.001 0.631 0.368
J66 Airway disease due to specific organic dust
0.001 0.631 0.368
J63 Pneumoconiosis due to other inorganic dusts
0.001 0.631 0.368
J62 Pneumoconiosis due to dust containing silica
0.001 0.631 0.368
J65 Pneumoconiosis associated with tuberculosis
0.001 0.631 0.368
J64 Unspecified pneumoconiosis
0.001 0.631 0.368
J60 Coalworker's pneumoconiosis
0.001 0.631 0.368
O36 Maternal care for other known or suspected foetal problems
0.369 0.631 0.000
K76.8 Other specified diseases of liver
0.000 0.632 0.367
K71.9 Toxic liver disease, unspecified
0.000 0.633 0.367
K71.8 Toxic liver disease with other disorders of liver
0.000 0.633 0.367
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.633 0.367
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.633 0.367
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.633 0.367
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.633 0.367
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.633 0.367
K71.2 Toxic liver disease with acute hepatitis
0.000 0.633 0.367
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.633 0.367
K71.0 Toxic liver disease with cholestasis
0.000 0.633 0.367
K73.9 Chronic hepatitis, unspecified
0.000 0.633 0.367
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.633 0.367
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.633 0.367
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.633 0.367
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.633 0.367
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.633 0.367
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.633 0.367
E28.9 Ovarian dysfunction, unspecified
0.001 0.633 0.365
E28.8 Other ovarian dysfunction
0.001 0.633 0.365
E28.3 Primary ovarian failure
0.001 0.633 0.365
E28.1 Androgen excess
0.001 0.633 0.365
E28.0 Oestrogen excess
0.001 0.633 0.365
O62.9 Abnormality of forces of labour, unspecified
0.366 0.634 0.000
O62.8 Other abnormalities of forces of labour
0.366 0.634 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.366 0.634 0.000
O62.1 Secondary uterine inertia
0.366 0.634 0.000
E27.9 Disorder of adrenal gland, unspecified
0.001 0.636 0.362
E27.8 Other specified disorders of adrenal gland
0.001 0.636 0.362
E27.5 Adrenomedullary hyperfunction
0.001 0.636 0.362
E27.3 Drug-induced adrenocortical insufficiency
0.001 0.636 0.362
E27.2 Addisonian crisis
0.001 0.636 0.362
E27.1 Primary adrenocortical insufficiency
0.001 0.636 0.362
E27.0 Other adrenocortical overactivity
0.001 0.636 0.362
O41 Other disorders of amniotic fluid and membranes
0.363 0.636 0.000
K29.7 Gastritis, unspecified
0.000 0.637 0.363
K75.0 Abscess of liver
0.000 0.638 0.362
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.360 0.640 0.000
O69.9 Labour and delivery complicated by cord complication, unspecified
0.360 0.640 0.000
O69.8 Labour and delivery complicated by other cord complications
0.360 0.640 0.000
O69.5 Labour and delivery complicated by vascular lesion of cord
0.360 0.640 0.000
O69.4 Labour and delivery complicated by vasa praevia
0.360 0.640 0.000
O69.3 Labour and delivery complicated by short cord
0.360 0.640 0.000
O69.0 Labour and delivery complicated by prolapse of cord
0.360 0.640 0.000
O24 Diabetes mellitus in pregnancy
0.359 0.640 0.001
O23 Infections of genito-urinary tract in pregnancy
0.358 0.642 0.001
E15 Nondiabetic hypoglycaemic coma
0.003 0.642 0.355
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.356 0.643 0.001
O97 Death from sequelae of direct obstetric causes
0.356 0.643 0.001
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.356 0.643 0.001
O95 Obstetric death of unspecified cause
0.356 0.643 0.001
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.356 0.643 0.001
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.353 0.646 0.002
E28.2 Polycystic ovarian syndrome
0.001 0.646 0.352
O69.2 Labour and delivery complicated by other cord entanglement
0.353 0.647 0.000
O45 Premature separation of placenta [abruptio placentae]
0.353 0.647 0.000
O44 Placenta praevia
0.353 0.647 0.000
O33 Maternal care for known or suspected disproportion
0.353 0.647 0.000
O31 Complications specific to multiple gestation
0.353 0.647 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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