TreeWAS – Variant ID: rs11763353

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.845	0.155
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.845	0.155
T42.4 Benzodiazepines	0.000	0.846	0.154
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.855	0.145
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.856	0.144
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.857	0.143
T43.2 Other and unspecified antidepressants	0.000	0.864	0.136
T50.9 Other and unspecified drugs, medicaments and biological substances	0.000	0.864	0.136
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.866	0.134
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.872	0.127
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.875	0.125
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.876	0.124
T42.1 Iminostilbenes	0.000	0.877	0.123
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.881	0.119
T46.1 Calcium-channel blockers	0.000	0.881	0.119
T36 Poisoning by systemic antibiotics	0.000	0.882	0.118
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.885	0.114
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.000	0.886	0.114
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.886	0.113
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.888	0.112
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.888	0.111
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.888	0.111
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.888	0.111
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.888	0.111
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.889	0.111
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.000	0.889	0.111
T42.5 Mixed antiepileptics, not elsewhere classified	0.000	0.889	0.111
T42.3 Barbiturates	0.000	0.889	0.111
T42.2 Succinimides and oxazolidinediones	0.000	0.889	0.111
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.889	0.110
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.890	0.110
T40.2 Other opioids	0.000	0.891	0.109
T42.0 Hydantoin derivatives	0.000	0.891	0.109
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.895	0.104
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.896	0.104
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.896	0.104
T46.7 Peripheral vasodilators	0.000	0.896	0.104
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.896	0.104
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.896	0.104
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.896	0.104
T50.8 Diagnostic agents	0.000	0.897	0.103
T50.7 Analeptics and opioid receptor antagonists	0.000	0.897	0.103
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.897	0.103
T50.5 Appetite depressants	0.000	0.897	0.103
T50.4 Drugs affecting uric acid metabolism	0.000	0.897	0.103
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.897	0.103
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.897	0.103
T50.1 Loop [high-ceiling] diuretics	0.000	0.897	0.103
T50.0 Mineralocorticoids and their antagonists	0.000	0.897	0.103
T43.9 Psychotropic drug, unspecified	0.000	0.897	0.102
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.897	0.102
T43.6 Psychostimulants with abuse potential	0.000	0.897	0.102
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.897	0.102
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.901	0.099
T40.6 Other and unspecified narcotics	0.000	0.905	0.095
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.908	0.092
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.908	0.092
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.908	0.092
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.908	0.092
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.908	0.092
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.908	0.092
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.908	0.092
T44.0 Anticholinesterase agents	0.000	0.908	0.092
T36.0 Penicillins	0.000	0.908	0.091
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.908	0.091
T38.9 Other and unspecified hormone antagonists	0.000	0.910	0.090
T38.8 Other and unspecified hormones and their synthetic substitutes	0.000	0.910	0.090
T38.7 Androgens and anabolic congeners	0.000	0.910	0.090
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.910	0.090
T38.5 Other oestrogens and progestogens	0.000	0.910	0.090
T38.4 Oral contraceptives	0.000	0.910	0.090
T38.2 Antithyroid drugs	0.000	0.910	0.090
T38.0 Glucocorticoids and synthetic analogues	0.000	0.910	0.090
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.911	0.089
T40.8 Lysergide [LSD]	0.000	0.911	0.089
T40.7 Cannabis (derivatives)	0.000	0.911	0.089
T40.5 Cocaine	0.000	0.911	0.089
T40.3 Methadone	0.000	0.911	0.089
T40.1 Heroin	0.000	0.911	0.089
T40.0 Opium	0.000	0.911	0.089
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.915	0.085
T36.9 Systemic antibiotic, unspecified	0.000	0.915	0.085
T36.8 Other systemic antibiotics	0.000	0.915	0.085
T36.7 Antifungal antibiotics, systemically used	0.000	0.915	0.085
T36.6 Rifamycins	0.000	0.915	0.085
T36.5 Aminoglycosides	0.000	0.915	0.085
T36.4 Tetracyclines	0.000	0.915	0.085
T36.3 Macrolides	0.000	0.915	0.085
T36.2 Chloramphenicol group	0.000	0.915	0.085
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.915	0.085
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.916	0.083
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.918	0.082
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.918	0.082
T47.7 Emetics	0.000	0.918	0.082
T47.6 Antidiarrhoeal drugs	0.000	0.918	0.082
T47.5 Digestants	0.000	0.918	0.082
T47.4 Other laxatives	0.000	0.918	0.082
T47.3 Saline and osmotic laxatives	0.000	0.918	0.082
T47.2 Stimulant laxatives	0.000	0.918	0.082
T47.0 Histamine H(2)-receptor antagonists	0.000	0.918	0.082
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.920	0.080
T37.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.920	0.080
T37.5 Antiviral drugs	0.000	0.920	0.080
T37.4 Anthelminthics	0.000	0.920	0.080
T37.3 Other antiprotozoal drugs	0.000	0.920	0.080
T37.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.920	0.080
T37.1 Antimycobacterial drugs	0.000	0.920	0.080
T37.0 Sulphonamides	0.000	0.920	0.080
T41.5 Therapeutic gases	0.000	0.920	0.080
T41.4 Anaesthetic, unspecified	0.000	0.920	0.080
T41.3 Local anaesthetics	0.000	0.920	0.080
T41.2 Other and unspecified general anaesthetics	0.000	0.920	0.080
T41.1 Intravenous anaesthetics	0.000	0.920	0.080
T41.0 Inhaled anaesthetics	0.000	0.920	0.080
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.920	0.080
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.920	0.080
T48.5 Anti-common-cold drugs	0.000	0.920	0.080
T48.4 Expectorants	0.000	0.920	0.080
T48.3 Antitussives	0.000	0.920	0.080
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.920	0.080
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.920	0.080
T48.0 Oxytocic drugs	0.000	0.920	0.080
T49.9 Topical agent, unspecified	0.000	0.920	0.080
T49.8 Other topical agents	0.000	0.920	0.080
T49.7 Dental drugs, topically applied	0.000	0.920	0.080
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.920	0.080
T49.5 Ophthalmological drugs and preparations	0.000	0.920	0.080
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.920	0.080
T49.3 Emollients, demulcents and protectants	0.000	0.920	0.080
T49.2 Local astringents and local detergents	0.000	0.920	0.080
T49.1 Antipruritics	0.000	0.920	0.080
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.920	0.080
T38.1 Thyroid hormones and substitutes	0.000	0.924	0.076
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.076	0.924	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.925	0.075
T45.8 Other primarily systemic and haematological agents	0.000	0.925	0.075
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.925	0.075
T45.6 Fibrinolysis-affecting drugs	0.000	0.925	0.075
T45.4 Iron and its compounds	0.000	0.925	0.075
T45.3 Enzymes, not elsewhere classified	0.000	0.925	0.075
T45.2 Vitamins, not elsewhere classified	0.000	0.925	0.075
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.925	0.075
T45.5 Anticoagulants	0.000	0.925	0.075
T45.0 Antiallergic and antiemetic drugs	0.000	0.932	0.068
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.936	0.064
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.936	0.063
T40.4 Other synthetic narcotics	0.000	0.939	0.061
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.951	0.049
T39.4 Antirheumatics, not elsewhere classified	0.000	0.954	0.046
T39.2 Pyrazolone derivatives	0.000	0.954	0.046
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.956	0.044
T39.1 4-Aminophenol derivatives	0.000	0.959	0.041
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.965	0.035
S62.60 Fracture of other finger (closed)	0.000	0.968	0.032
T39.0 Salicylates	0.000	0.970	0.030
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.021	0.979	0.000
H18 Other disorders of cornea	0.021	0.979	0.000
H21 Other disorders of iris and ciliary body	0.021	0.979	0.000
H18.9 Disorder of cornea, unspecified	0.019	0.981	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.018	0.981	0.000
H20 Iridocyclitis	0.018	0.982	0.000
H16 Keratitis	0.018	0.982	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.018	0.982	0.000
C79 Secondary malignant neoplasm of other sites	0.018	0.982	0.000
H21.0 Hyphaema	0.017	0.982	0.000
H17 Corneal scars and opacities	0.017	0.983	0.000
H18.4 Corneal degeneration	0.017	0.983	0.000
H18.3 Changes in corneal membranes	0.017	0.983	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.017	0.983	0.000
H15 Disorders of sclera	0.017	0.983	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.016	0.984	0.000
H18.1 Bullous keratopathy	0.016	0.984	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.016	0.984	0.000
H18.2 Other corneal oedema	0.016	0.984	0.000
C79.9 Secondary malignant neoplasm, unspecified site	0.016	0.984	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.016	0.984	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.016	0.984	0.000
H21.2 Degeneration of iris and ciliary body	0.015	0.984	0.000
H18.7 Other corneal deformities	0.015	0.985	0.000
H18.0 Corneal pigmentations and deposits	0.015	0.985	0.000
H16.4 Corneal neovascularisation	0.015	0.985	0.000
H18.8 Other specified disorders of cornea	0.015	0.985	0.000
H20.8 Other iridocyclitis	0.015	0.985	0.000
H21.4 Pupillary membranes	0.015	0.985	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.015	0.985	0.000
H18.5 Hereditary corneal dystrophies	0.015	0.985	0.000
H20.1 Chronic iridocyclitis	0.015	0.985	0.000
H17.9 Corneal scar and opacity, unspecified	0.015	0.985	0.000
H18.6 Keratoconus	0.014	0.986	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.014	0.986	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.014	0.986	0.000
H20.0 Acute and subacute iridocyclitis	0.014	0.986	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.013	0.986	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.013	0.986	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.013	0.986	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.013	0.986	0.000
H15.1 Episcleritis	0.013	0.987	0.000
H16.2 Keratoconjunctivitis	0.013	0.987	0.000
H20.2 Lens-induced iridocyclitis	0.013	0.987	0.000
H16.9 Keratitis, unspecified	0.013	0.987	0.000
H16.8 Other keratitis	0.013	0.987	0.000
H16.3 Interstitial and deep keratitis	0.013	0.987	0.000
H21.8 Other specified disorders of iris and ciliary body	0.013	0.987	0.000
S62.6 Fracture of other finger	0.000	0.987	0.013
H15.8 Other disorders of sclera	0.013	0.987	0.000
H17.8 Other corneal scars and opacities	0.013	0.987	0.000
H17.1 Other central corneal opacity	0.013	0.987	0.000
H17.0 Adherent leukoma	0.013	0.987	0.000
H15.9 Disorder of sclera, unspecified	0.012	0.987	0.000
H15.0 Scleritis	0.012	0.987	0.000
H16.0 Corneal ulcer	0.012	0.988	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.012	0.988	0.000
M17.9 Gonarthrosis, unspecified	0.000	0.988	0.012
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.011	0.988	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.011	0.988	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.011	0.988	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.011	0.988	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.011	0.989	0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.989	0.011
H20.9 Iridocyclitis, unspecified	0.011	0.989	0.000
N23 Unspecified renal colic	0.011	0.989	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.000	0.990	0.010
M23.2 Derangement of meniscus due to old tear or injury	0.000	0.991	0.009
M23.21 Derangement of meniscus due to old tear or injury (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.992	0.008
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.008	0.992	0.000
I21.4 Acute subendocardial myocardial infarction	0.008	0.992	0.000
D63.0 Anaemia in neoplastic disease	0.008	0.992	0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)	0.000	0.992	0.008
C79.6 Secondary malignant neoplasm of ovary	0.007	0.992	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.008	0.992	0.000
Q50-Q56 Congenital malformations of genital organs	0.008	0.992	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.000	0.992	0.008
M23.29 Derangement of meniscus due to old tear or injury (Unspecified ligament or Unspecified meniscus)	0.000	0.992	0.008
C79.2 Secondary malignant neoplasm of skin	0.007	0.993	0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.993	0.007
Q00-Q07 Congenital malformations of the nervous system	0.007	0.993	0.000
Q54 Hypospadias	0.007	0.993	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.007	0.993	0.000
S62.61 Fracture of other finger (open)	0.000	0.993	0.007
Q80-Q89 Other congenital malformations	0.007	0.993	0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified	0.007	0.993	0.000
Q05 Spina bifida	0.007	0.993	0.000
Q05.9 Spina bifida, unspecified	0.007	0.993	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.000	0.993	0.007
Q60-Q64 Congenital malformations of the urinary system	0.007	0.993	0.000
M23.27 Derangement of meniscus due to old tear or injury-Capsular	0.000	0.993	0.006
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.007	0.993	0.000
Q78 Other osteochondrodysplasias	0.007	0.993	0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest	0.006	0.993	0.000
Q35-Q37 Cleft lip and cleft palate	0.006	0.993	0.000
Q79.6 Ehlers-Danlos syndrome	0.006	0.994	0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.006	0.994	0.000
Q54.9 Hypospadias, unspecified	0.006	0.994	0.000
Q53 Undescended testicle	0.006	0.994	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.006	0.994	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.006	0.994	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.006	0.994	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.006	0.994	0.000
M23.61 Other spontaneous disruption of ligament(s) of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.994	0.006
Q63 Other congenital malformations of kidney	0.006	0.994	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.006	0.994	0.000
M23 Internal derangement of knee	0.000	0.994	0.006
Q30-Q34 Congenital malformations of the respiratory system	0.006	0.994	0.000
Q54.0 Hypospadias, balanic	0.006	0.994	0.000
Q55 Other congenital malformations of male genital organs	0.006	0.994	0.000
Q74 Other congenital malformations of limb(s)	0.006	0.994	0.000
M23.6 Other spontaneous disruption of ligament(s) of knee	0.000	0.994	0.006
M45 Ankylosing spondylitis	0.006	0.994	0.000
Q76 Congenital malformations of spine and bony thorax	0.006	0.994	0.000
Q89 Other congenital malformations, not elsewhere classified	0.006	0.994	0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine	0.006	0.994	0.000
Q75 Other congenital malformations of skull and face bones	0.006	0.994	0.000
Q73 Reduction defects of unspecified limb	0.006	0.994	0.000
Q72 Reduction defects of lower limb	0.006	0.994	0.000
Q71 Reduction defects of upper limb	0.006	0.994	0.000
Q70 Syndactyly	0.006	0.994	0.000
Q69 Polydactyly	0.006	0.994	0.000
Q68 Other congenital musculoskeletal deformities	0.006	0.994	0.000
Q66 Congenital deformities of feet	0.006	0.994	0.000
O20.0 Threatened abortion	0.000	0.994	0.006
Q60.0 Renal agenesis, unilateral	0.006	0.994	0.000
N02.9 Unspecified	0.006	0.994	0.000
O20 Haemorrhage in early pregnancy	0.000	0.994	0.006
Q38-Q45 Other congenital malformations of the digestive system	0.006	0.994	0.000
Q56 Indeterminate sex and pseudohermaphroditism	0.006	0.994	0.000
Q52 Other congenital malformations of female genitalia	0.006	0.994	0.000
Q78.0 Osteogenesis imperfecta	0.006	0.994	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.006	0.994	0.000
Q67.5 Congenital deformity of spine	0.006	0.994	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.006	0.994	0.000
Q54.1 Hypospadias, penile	0.005	0.994	0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)	0.000	0.994	0.006
Q98 Other sex chromosome abnormalities, male phenotype, not elsewhere classified	0.005	0.994	0.000
M23.0 Cystic meniscus	0.000	0.995	0.005
Q50.4 Embryonic cyst of Fallopian tube	0.005	0.995	0.000
Q85 Phakomatoses, not elsewhere classified	0.005	0.995	0.000
Q65 Congenital deformities of hip	0.005	0.995	0.000
Q06 Other congenital malformations of spinal cord	0.005	0.995	0.000
Q04 Other congenital malformations of brain	0.005	0.995	0.000
Q03 Congenital hydrocephalus	0.005	0.995	0.000
Q01 Encephalocele	0.005	0.995	0.000
Q00 Anencephaly and similar malformations	0.005	0.995	0.000
Q02 Microcephaly	0.005	0.995	0.000
Q37 Cleft palate with cleft lip	0.005	0.995	0.000
Q54.8 Other hypospadias	0.005	0.995	0.000
Q54.4 Congenital chordee	0.005	0.995	0.000
Q54.3 Hypospadias, perineal	0.005	0.995	0.000
Q54.2 Hypospadias, penoscrotal	0.005	0.995	0.000
Q63.1 Lobulated, fused and horseshoe kidney	0.005	0.995	0.000
Q24 Other congenital malformations of heart	0.005	0.995	0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified	0.005	0.995	0.000
Q84 Other congenital malformations of integument	0.005	0.995	0.000
Q81 Epidermolysis bullosa	0.005	0.995	0.000
Q80 Congenital ichthyosis	0.005	0.995	0.000
M23.8 Other internal derangements of knee	0.000	0.995	0.005
Q79.9 Congenital malformation of musculoskeletal system, unspecified	0.005	0.995	0.000
Q79.8 Other congenital malformations of musculoskeletal system	0.005	0.995	0.000
Q79.5 Other congenital malformations of abdominal wall	0.005	0.995	0.000
Q79.4 Prune belly syndrome	0.005	0.995	0.000
Q79.3 Gastroschisis	0.005	0.995	0.000
Q79.2 Exomphalos	0.005	0.995	0.000
Q79.1 Other congenital malformations of diaphragm	0.005	0.995	0.000
Q79.0 Congenital diaphragmatic hernia	0.005	0.995	0.000
Q23 Congenital malformations of aortic and mitral valves	0.005	0.995	0.000
Q53.1 Undescended testicle, unilateral	0.005	0.995	0.000
Q05.8 Sacral spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.7 Lumbar spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.6 Thoracic spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.5 Cervical spina bifida without hydrocephalus	0.005	0.995	0.000
Q05.4 Unspecified spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.3 Sacral spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.2 Lumbar spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.1 Thoracic spina bifida with hydrocephalus	0.005	0.995	0.000
Q05.0 Cervical spina bifida with hydrocephalus	0.005	0.995	0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.005
Q89.2 Congenital malformations of other endocrine glands	0.005	0.995	0.000
M23.5 Chronic instability of knee	0.000	0.995	0.005
Q18 Other congenital malformations of face and neck	0.005	0.995	0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter	0.005	0.995	0.000
Q63.0 Accessory kidney	0.005	0.995	0.000
Q83 Congenital malformations of breast	0.005	0.995	0.000
Q96 Turner's syndrome	0.005	0.995	0.000
Q51 Congenital malformations of uterus and cervix	0.005	0.995	0.000
Q99 Other chromosome abnormalities, not elsewhere classified	0.005	0.995	0.000
Q97 Other sex chromosome abnormalities, female phenotype, not elsewhere classified	0.005	0.995	0.000
Q95 Balanced rearrangements and structural markers, not elsewhere classified	0.005	0.995	0.000
Q93 Monosomies and deletions from the autosomes, not elsewhere classified	0.005	0.995	0.000
Q92 Other trisomies and partial trisomies of the autosomes, not elsewhere classified	0.005	0.995	0.000
Q91 Edwards' syndrome and Patau's syndrome	0.005	0.995	0.000
Q90 Down's syndrome	0.005	0.995	0.000
Q78.9 Osteochondrodysplasia, unspecified	0.005	0.995	0.000
Q78.8 Other specified osteochondrodysplasias	0.005	0.995	0.000
Q78.6 Multiple congenital exostoses	0.005	0.995	0.000
Q78.5 Metaphyseal dysplasia	0.005	0.995	0.000
Q78.4 Enchondromatosis	0.005	0.995	0.000
Q78.3 Progressive diaphyseal dysplasia	0.005	0.995	0.000
Q78.2 Osteopetrosis	0.005	0.995	0.000
Q78.1 Polyostotic fibrous dysplasia	0.005	0.995	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.995	0.005
Q67.8 Other congenital deformities of chest	0.005	0.995	0.000
Q67.7 Pectus carinatum	0.005	0.995	0.000
Q67.6 Pectus excavatum	0.005	0.995	0.000
Q67.4 Other congenital deformities of skull, face and jaw	0.005	0.995	0.000
Q67.3 Plagiocephaly	0.005	0.995	0.000
Q67.2 Dolichocephaly	0.005	0.995	0.000
Q67.1 Compression facies	0.005	0.995	0.000
Q67.0 Facial asymmetry	0.005	0.995	0.000
S62 Fracture at wrist and hand level	0.000	0.995	0.005
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)	0.000	0.995	0.005
Q36 Cleft lip	0.005	0.995	0.000
Q35 Cleft palate	0.005	0.995	0.000
N02 Recurrent and persistent haematuria	0.005	0.995	0.000
Q85.9 Phakomatosis, unspecified	0.005	0.995	0.000
Q64 Other congenital malformations of urinary system	0.005	0.995	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.005	0.995	0.000
Q50.5 Embryonic cyst of broad ligament	0.005	0.995	0.000
Q50.3 Other congenital malformations of ovary	0.005	0.995	0.000
Q50.2 Congenital torsion of ovary	0.005	0.995	0.000
Q50.1 Developmental ovarian cyst	0.005	0.995	0.000
Q50.0 Congenital absence of ovary	0.005	0.995	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.005	0.995	0.000
Q39 Congenital malformations of oesophagus	0.005	0.995	0.000
Q87.4 Marfan's syndrome	0.005	0.995	0.000
Q98.4 Klinefelter's syndrome, unspecified	0.005	0.995	0.000
Q07 Other congenital malformations of nervous system	0.005	0.995	0.000
Q45 Other congenital malformations of digestive system	0.005	0.995	0.000
Z00.0 General medical examination	0.000	0.995	0.005
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.995	0.005
Q53.9 Undescended testicle, unspecified	0.005	0.995	0.000
Q53.2 Undescended testicle, bilateral	0.005	0.995	0.000
Q53.0 Ectopic testis	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
Q66.2 Metatarsus varus	0.005	0.995	0.000
Q17 Other congenital malformations of ear	0.005	0.995	0.000
Q16 Congenital malformations of ear causing impairment of hearing	0.005	0.995	0.000
Q15 Other congenital malformations of eye	0.005	0.995	0.000
Q14 Congenital malformations of posterior segment of eye	0.005	0.995	0.000
Q13 Congenital malformations of anterior segment of eye	0.005	0.995	0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos	0.005	0.995	0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit	0.005	0.995	0.000
Q55.6 Other congenital malformations of penis	0.005	0.995	0.000
Q23.1 Congenital insufficiency of aortic valve	0.005	0.995	0.000
Q63.2 Ectopic kidney	0.005	0.995	0.000
Q66.7 Pes cavus	0.005	0.995	0.000
Q87.5 Other congenital malformation syndromes with other skeletal changes	0.005	0.995	0.000
Q87.3 Congenital malformation syndromes involving early overgrowth	0.005	0.995	0.000
Q87.2 Congenital malformation syndromes predominantly involving limbs	0.005	0.995	0.000
Q87.1 Congenital malformation syndromes predominantly associated with short stature	0.005	0.995	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.005	0.995	0.000
M45.X2 Ankylosing spondylitis (Cervical region)	0.005	0.995	0.000
Q74.0 Other congenital malformations of upper limb(s), including shoulder girdle	0.004	0.995	0.000
Q60.6 Potter's syndrome	0.004	0.995	0.000
Q60.5 Renal hypoplasia, unspecified	0.004	0.995	0.000
Q60.4 Renal hypoplasia, bilateral	0.004	0.995	0.000
Q60.3 Renal hypoplasia, unilateral	0.004	0.995	0.000
Q60.1 Renal agenesis, bilateral	0.004	0.995	0.000
Q37.9 Unspecified cleft palate with unilateral cleft lip	0.004	0.995	0.000
Q63.9 Congenital malformation of kidney, unspecified	0.004	0.995	0.000
Q63.8 Other specified congenital malformations of kidney	0.004	0.995	0.000
Q63.3 Hyperplastic and giant kidney	0.004	0.995	0.000
Q76.0 Spina bifida occulta	0.005	0.995	0.000
Q82 Other congenital malformations of skin	0.004	0.995	0.000
Q24.8 Other specified congenital malformations of heart	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.004	0.995	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.004	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.004	0.995	0.000
Q34 Other congenital malformations of respiratory system	0.004	0.995	0.000
Q33 Congenital malformations of lung	0.004	0.995	0.000
Q32 Congenital malformations of trachea and bronchus	0.004	0.995	0.000
Q31 Congenital malformations of larynx	0.004	0.995	0.000
Q30 Congenital malformations of nose	0.004	0.995	0.000
M23.69 Other spontaneous disruption of ligament(s) of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.995	0.004
M23.67 Other spontaneous disruption of ligament(s) of knee (Capsular ligament)	0.000	0.995	0.004
M23.66 Other spontaneous disruption of ligament(s) of knee-O/unsp	0.000	0.995	0.004
M23.65 Other spontaneous disruption of ligament(s) of knee-Pst hrn	0.000	0.995	0.004
M23.64 Other spontaneous disruption of ligament(s) of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.995	0.004
M23.63 Other spontaneous disruption of ligament(s) of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.995	0.004
M23.62 Other spontaneous disruption of ligament(s) of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.995	0.004
M23.60 Other spontaneous disruption of ligament(s) of knee (Multiple sites)	0.000	0.995	0.004
Q55.9 Congenital malformation of male genital organ, unspecified	0.004	0.995	0.000
Q55.8 Other specified congenital malformations of male genital organs	0.004	0.995	0.000
Q55.5 Congenital absence and aplasia of penis	0.004	0.995	0.000
Q55.4 Other congenital malformations of vas deferens, epididymis, seminal vesicles and prostate	0.004	0.995	0.000
Q55.3 Atresia of vas deferens	0.004	0.995	0.000
Q55.2 Other congenital malformations of testis and scrotum	0.004	0.995	0.000
Q55.1 Hypoplasia of testis and scrotum	0.004	0.995	0.000
Q55.0 Absence and aplasia of testis	0.004	0.995	0.000
Q74.9 Unspecified congenital malformation of limb(s)	0.004	0.995	0.000
Q74.8 Other specified congenital malformations of limb(s)	0.004	0.995	0.000
Q74.3 Arthrogryposis multiplex congenita	0.004	0.995	0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle	0.004	0.995	0.000
Q74.1 Congenital malformation of knee	0.004	0.995	0.000
Q12 Congenital lens malformations	0.004	0.995	0.000
N02.8 Other	0.005	0.995	0.000
Q18.1 Preauricular sinus and cyst	0.004	0.995	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.004	0.995	0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.004	0.995	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.004	0.995	0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.004	0.995	0.000
M45.X4 Ankylosing spondylitis (Thoracic region)	0.004	0.995	0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.004	0.995	0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.004	0.995	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.004	0.995	0.000
Q76.8 Other congenital malformations of bony thorax	0.004	0.995	0.000
Q76.7 Congenital malformation of sternum	0.004	0.995	0.000
Q76.6 Other congenital malformations of ribs	0.004	0.995	0.000
Q76.5 Cervical rib	0.004	0.995	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.004	0.995	0.000
Q76.2 Congenital spondylolisthesis	0.004	0.995	0.000
Q76.1 Klippel-Feil syndrome	0.004	0.995	0.000
M23.1 Discoid meniscus (congenital)	0.000	0.995	0.004
M17.0 Primary gonarthrosis, bilateral	0.000	0.995	0.005
Q66.9 Congenital deformity of feet, unspecified	0.004	0.995	0.000
Q66.6 Other congenital valgus deformities of feet	0.004	0.995	0.000
Q66.5 Congenital pes planus	0.004	0.995	0.000
Q66.4 Talipes calcaneovalgus	0.004	0.995	0.000
Q66.3 Other congenital varus deformities of feet	0.004	0.995	0.000
Q66.1 Talipes calcaneovarus	0.004	0.995	0.000
Q66.0 Talipes equinovarus	0.004	0.995	0.000
Q89.9 Congenital malformation, unspecified	0.004	0.995	0.000
Q89.8 Other specified congenital malformations	0.004	0.995	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.004	0.995	0.000
Q89.4 Conjoined twins	0.004	0.995	0.000
Q89.3 Situs inversus	0.004	0.995	0.000
Q89.1 Congenital malformations of adrenal gland	0.004	0.995	0.000
Q89.0 Congenital malformations of spleen	0.004	0.995	0.000
Q68.8 Other specified congenital musculoskeletal deformities	0.004	0.995	0.000
Q68.5 Congenital bowing of long bones of leg, unspecified	0.004	0.995	0.000
Q68.4 Congenital bowing of tibia and fibula	0.004	0.995	0.000
Q68.3 Congenital bowing of femur	0.004	0.995	0.000
Q68.2 Congenital deformity of knee	0.004	0.995	0.000
Q68.1 Congenital deformity of hand	0.004	0.995	0.000
Q68.0 Congenital deformity of sternocleidomastoid muscle	0.004	0.995	0.000
Q69.9 Polydactyly, unspecified	0.004	0.995	0.000
Q69.2 Accessory toe(s)	0.004	0.995	0.000
Q69.1 Accessory thumb(s)	0.004	0.995	0.000
Q69.0 Accessory finger(s)	0.004	0.995	0.000
Q70.9 Syndactyly, unspecified	0.004	0.995	0.000
Q70.4 Polysyndactyly	0.004	0.995	0.000
Q70.3 Webbed toes	0.004	0.995	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations