TreeWAS – Variant ID: rs118084537

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.071	0.929	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.067	0.933	0.000
O68 Labour and delivery complicated by foetal stress [distress]	0.064	0.936	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.062	0.938	0.000
Y43.3 Other antineoplastic drugs	0.057	0.943	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.054	0.946	0.000
Y43 Primarily systemic agents	0.052	0.948	0.000
Y52 Agents primarily affecting the cardiovascular system	0.051	0.949	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.051	0.949	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.049	0.951	0.000
K76.8 Other specified diseases of liver	0.000	0.953	0.047
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.047	0.953	0.000
K76 Other diseases of liver	0.000	0.955	0.045
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.045	0.955	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.044	0.956	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.043	0.957	0.000
K76.6 Portal hypertension	0.000	0.957	0.043
D12.4 Descending colon	0.042	0.958	0.000
K70-K77 Diseases of liver	0.000	0.958	0.042
Y48 Anaesthetics and therapeutic gases	0.041	0.959	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.959	0.041
Y51 Drugs primarily affecting the autonomic nervous system	0.041	0.959	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.959	0.041
Y52.4 Angiotensin-converting-enzyme inhibitors	0.040	0.959	0.000
Y44 Agents primarily affecting blood constituents	0.040	0.960	0.000
O60-O75 Complications of labour and delivery	0.040	0.960	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.040	0.960	0.000
K72 Hepatic failure, not elsewhere classified	0.000	0.960	0.040
Y40 Systemic antibiotics	0.040	0.960	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.039	0.961	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.039	0.961	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.039	0.961	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.038	0.962	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.038	0.962	0.000
K72.9 Hepatic failure, unspecified	0.000	0.962	0.038
Y43.1 Antineoplastic antimetabolites	0.038	0.962	0.000
Y43.9 Primarily systemic agent, unspecified	0.038	0.962	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.038	0.962	0.000
Y43.6 Enzymes, not elsewhere classified	0.038	0.962	0.000
Y43.5 Acidifying and alkalising agents	0.038	0.962	0.000
Y43.2 Antineoplastic natural products	0.038	0.962	0.000
Y43.0 Antiallergic and antiemetic drugs	0.038	0.962	0.000
Y52.1 Calcium-channel blockers	0.037	0.963	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.036	0.963	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.036	0.963	0.000
Y52.7 Peripheral vasodilators	0.036	0.963	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.036	0.963	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.036	0.963	0.000
Y59 Other and unspecified vaccines and biological substances	0.037	0.963	0.000
Y58 Bacterial vaccines	0.037	0.963	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.037	0.963	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.037	0.963	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.037	0.963	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.036	0.963	0.000
Y57 Other and unspecified drugs and medicaments	0.036	0.964	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.036	0.964	0.000
D12.5 Sigmoid colon	0.036	0.964	0.000
O62 Abnormalities of forces of labour	0.035	0.964	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.965	0.035
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.035	0.965	0.000
Y48.2 Other and unspecified general anaesthetics	0.035	0.965	0.000
D12.6 Colon, unspecified	0.034	0.966	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.034	0.966	0.000
Y40.1 Cefalosporins and other -lactam antibiotics	0.033	0.967	0.000
K75 Other inflammatory liver diseases	0.000	0.967	0.033
Y44.2 Anticoagulants	0.033	0.967	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.967	0.033
K76.4 Peliosis hepatis	0.000	0.967	0.033
K76.3 Infarction of liver	0.000	0.967	0.033
K76.2 Central haemorrhagic necrosis of liver	0.000	0.967	0.033
K76.1 Chronic passive congestion of liver	0.000	0.967	0.033
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.032	0.968	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.032	0.968	0.000
O75.0 Maternal distress during labour and delivery	0.032	0.968	0.000
Y54.3 Benzothiadiazine derivatives	0.032	0.968	0.000
Y47.1 Benzodiazepines	0.031	0.969	0.000
Y40.9 Systemic antibiotic, unspecified	0.031	0.969	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.031	0.969	0.000
K74.5 Biliary cirrhosis, unspecified	0.000	0.969	0.031
O69 Labour and delivery complicated by umbilical cord complications	0.031	0.969	0.000
O62.3 Precipitate labour	0.031	0.969	0.000
Y45.8 Other analgesics and antipyretics	0.031	0.969	0.000
Y40.8 Other systemic antibiotics	0.030	0.970	0.000
O73 Retained placenta and membranes, without haemorrhage	0.030	0.970	0.000
K74.3 Primary biliary cirrhosis	0.000	0.970	0.030
K77 Liver disorders in diseases classified elsewhere	0.000	0.970	0.030
K71 Toxic liver disease	0.000	0.970	0.030
Y48.5 Therapeutic gases	0.030	0.970	0.000
Y48.4 Anaesthetic, unspecified	0.030	0.970	0.000
Y48.1 Parenteral anaesthetics	0.030	0.970	0.000
Y48.0 Inhaled anaesthetics	0.030	0.970	0.000
K74.4 Secondary biliary cirrhosis	0.000	0.970	0.030
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.970	0.030
K74.1 Hepatic sclerosis	0.000	0.970	0.030
Y43.4 Immunosuppressive agents	0.029	0.970	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.029	0.970	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.029	0.970	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.029	0.970	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.029	0.970	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.029	0.970	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.029	0.970	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.029	0.970	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.029	0.970	0.000
Y51.0 Anticholinesterase agents	0.029	0.970	0.000
C67.9 Bladder, unspecified	0.000	0.970	0.030
O75.7 Vaginal delivery following previous Caesarean section	0.029	0.971	0.000
Y46.2 Hydantoin derivatives	0.029	0.971	0.000
K74.0 Hepatic fibrosis	0.000	0.971	0.029
O66 Other obstructed labour	0.029	0.971	0.000
Y48.3 Local anaesthetics	0.029	0.971	0.000
O75.2 Pyrexia during labour, not elsewhere classified	0.029	0.971	0.000
O71 Other obstetric trauma	0.029	0.971	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.029	0.971	0.000
Y44.7 Plasma substitutes	0.029	0.971	0.000
Y44.6 Natural blood and blood products	0.029	0.971	0.000
Y44.5 Thrombolytic drugs	0.029	0.971	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.029	0.971	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.029	0.971	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.029	0.971	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.029	0.971	0.000
O74 Complications of anaesthesia during labour and delivery	0.029	0.971	0.000
O65 Obstructed labour due to maternal pelvic abnormality	0.029	0.971	0.000
O60 Preterm delivery	0.029	0.971	0.000
Y54.9 Mineral salts, not elsewhere classified	0.029	0.971	0.000
Y54.8 Agents affecting uric acid metabolism	0.029	0.971	0.000
Y54.7 Agents affecting calcification	0.029	0.971	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.029	0.971	0.000
Y54.5 Other diuretics	0.029	0.971	0.000
Y54.4 Loop [high-ceiling] diuretics	0.029	0.971	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.029	0.971	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.029	0.971	0.000
Y54.0 Mineralocorticoids	0.029	0.971	0.000
K72.1 Chronic hepatic failure	0.000	0.971	0.028
K72.0 Acute and subacute hepatic failure	0.000	0.971	0.029
Y40.7 Antifungal antibiotics, systemically used	0.028	0.971	0.000
Y40.6 Rifamycins	0.028	0.971	0.000
Y40.5 Aminoglycosides	0.028	0.971	0.000
Y40.4 Tetracyclines	0.028	0.971	0.000
Y40.3 Macrolides	0.028	0.971	0.000
Y40.2 Chloramphenicol group	0.028	0.971	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.029	0.971	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.028	0.971	0.000
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.028	0.971	0.000
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.028	0.971	0.000
Y47.4 Bromine compounds	0.028	0.971	0.000
Y47.3 Paraldehyde	0.028	0.971	0.000
Y47.2 Chloral derivatives	0.028	0.971	0.000
Y47.0 Barbiturates, not elsewhere classified	0.028	0.971	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.028	0.972	0.000
Y45.5 4-Aminophenol derivatives	0.028	0.972	0.000
Y45.4 Antirheumatics	0.028	0.972	0.000
Y56.9 Topical agent, unspecified	0.028	0.972	0.000
Y56.8 Other topical agents	0.028	0.972	0.000
Y56.7 Dental drugs, topically applied	0.028	0.972	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.028	0.972	0.000
Y56.5 Ophthalmological drugs and preparations	0.028	0.972	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.028	0.972	0.000
Y56.3 Emollients, demulcents and protectants	0.028	0.972	0.000
Y56.2 Local astringents and local detergents	0.028	0.972	0.000
Y56.1 Antipruritics	0.028	0.972	0.000
D12.0 Caecum	0.028	0.972	0.000
Y57.5 X-ray contrast media	0.028	0.972	0.000
O75.9 Complication of labour and delivery, unspecified	0.028	0.972	0.000
O75.5 Delayed delivery after artificial rupture of membranes	0.028	0.972	0.000
O75.4 Other complications of obstetric surgery and procedures	0.028	0.972	0.000
O75.3 Other infection during labour	0.028	0.972	0.000
O75.1 Shock during or following labour and delivery	0.028	0.972	0.000
Y46.8 Antispasticity drugs	0.028	0.972	0.000
Y46.7 Anti-Parkinsonism drugs	0.028	0.972	0.000
Y46.6 Other and unspecified antiepileptics	0.028	0.972	0.000
Y46.5 Valproic acid	0.028	0.972	0.000
Y46.4 Iminostilbenes	0.028	0.972	0.000
Y46.3 Deoxybarbiturates	0.028	0.972	0.000
Y46.1 Oxazolidinediones	0.028	0.972	0.000
Y46.0 Succinimides	0.028	0.972	0.000
K73 Chronic hepatitis, not elsewhere classified	0.000	0.972	0.027
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.027	0.972	0.000
K76.7 Hepatorenal syndrome	0.000	0.973	0.027
Y45.0 Opioids and related analgesics	0.027	0.973	0.000
Y45.2 Propionic acid derivatives	0.027	0.973	0.000
D50.8 Other iron deficiency anaemias	0.027	0.973	0.000
O72 Postpartum haemorrhage	0.027	0.973	0.000
Y49.2 Other and unspecified antidepressants	0.027	0.973	0.000
Y50.9 Central nervous system stimulant, unspecified	0.026	0.973	0.000
Y50.8 Other central nervous system stimulants	0.026	0.973	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.026	0.973	0.000
Y50.1 Opioid receptor antagonists	0.026	0.973	0.000
Y50.0 Analeptics	0.026	0.973	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.026	0.973	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.026	0.973	0.000
Y53.7 Emetics	0.026	0.973	0.000
Y53.6 Antidiarrhoeal drugs	0.026	0.973	0.000
Y53.5 Digestants	0.026	0.973	0.000
Y53.4 Other laxatives	0.026	0.973	0.000
Y53.3 Saline and osmotic laxatives	0.026	0.973	0.000
Y53.2 Stimulant laxatives	0.026	0.973	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.026	0.973	0.000
Y53.0 Histamine H2-receptor antagonists	0.026	0.973	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.026	0.973	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.026	0.973	0.000
Y55.5 Anticommon cold drugs	0.026	0.973	0.000
Y55.4 Expectorants	0.026	0.973	0.000
Y55.3 Antitussives	0.026	0.973	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.026	0.973	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.026	0.973	0.000
Y55.0 Oxytocic drugs	0.026	0.973	0.000
Y58.9 Other and unspecified bacterial vaccines	0.026	0.973	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.026	0.973	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.026	0.973	0.000
Y58.5 Diphtheria vaccine	0.026	0.973	0.000
Y58.4 Tetanus vaccine	0.026	0.973	0.000
Y58.3 Plague vaccine	0.026	0.973	0.000
Y58.2 Cholera vaccine	0.026	0.973	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.026	0.973	0.000
Y58.0 BCG vaccine	0.026	0.973	0.000
Y59.9 Vaccine or biological substance, unspecified	0.026	0.973	0.000
Y59.8 Other specified vaccines and biological substances	0.026	0.973	0.000
Y59.3 Immunoglobulin	0.026	0.973	0.000
Y59.2 Protozoal vaccines	0.026	0.973	0.000
Y59.1 Rickettsial vaccines	0.026	0.973	0.000
Y59.0 Viral vaccines	0.026	0.973	0.000
K75.9 Inflammatory liver disease, unspecified	0.000	0.973	0.026
Y49.9 Psychotropic drug, unspecified	0.026	0.973	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.026	0.973	0.000
Y49.7 Psychostimulants with abuse potential	0.026	0.973	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.026	0.973	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.026	0.973	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.026	0.973	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.026	0.973	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.026	0.973	0.000
O62.2 Other uterine inertia	0.026	0.974	0.000
O62.0 Primary inadequate contractions	0.026	0.974	0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.026	0.974	0.000
Y49.5 Other antipsychotics and neuroleptics	0.026	0.974	0.000
Y57.8 Other drugs and medicaments	0.026	0.974	0.000
Y57.7 Vitamins, not elsewhere classified	0.026	0.974	0.000
Y57.6 Other diagnostic agents	0.026	0.974	0.000
Y57.4 Pharmaceutical excipients	0.026	0.974	0.000
Y57.3 Alcohol deterrents	0.026	0.974	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.026	0.974	0.000
Y57.1 Lipotropic drugs	0.026	0.974	0.000
Y57.0 Appetite depressants [anorectics]	0.026	0.974	0.000
O69.8 Labour and delivery complicated by other cord complications	0.026	0.974	0.000
Y45.1 Salicylates	0.026	0.974	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.026	0.974	0.000
O62.9 Abnormality of forces of labour, unspecified	0.026	0.974	0.000
O62.8 Other abnormalities of forces of labour	0.026	0.974	0.000
O62.1 Secondary uterine inertia	0.026	0.974	0.000
C67 Malignant neoplasm of bladder	0.000	0.974	0.026
O69.9 Labour and delivery complicated by cord complication, unspecified	0.025	0.975	0.000
O61 Failed induction of labour	0.025	0.975	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.975	0.025
K75.4 Autoimmune hepatitis	0.000	0.975	0.025
I10-I15 Hypertensive diseases	0.024	0.976	0.000
D12.1 Appendix	0.024	0.976	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.976	0.024
K75.2 Nonspecific reactive hepatitis	0.000	0.976	0.024
K75.1 Phlebitis of portal vein	0.000	0.976	0.024
O75.8 Other specified complications of labour and delivery	0.023	0.976	0.000
O73.0 Retained placenta, without haemorrhage	0.023	0.976	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.023	0.976	0.000
Y41.5 Antiviral drugs	0.023	0.976	0.000
Y41.4 Anthelminthics	0.023	0.976	0.000
Y41.3 Other antiprotozoal drugs	0.023	0.976	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.023	0.976	0.000
Y41.1 Antimycobacterial drugs	0.023	0.976	0.000
Y41.0 Sulphonamides	0.023	0.976	0.000
K70 Alcoholic liver disease	0.000	0.977	0.023
O64.8 Obstructed labour due to other malposition and malpresentation	0.023	0.977	0.000
Y57.9 Drug or medicament, unspecified	0.023	0.977	0.000
O70.0 First degree perineal laceration during delivery	0.000	0.977	0.023
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.023	0.977	0.000
O69.1 Labour and delivery complicated by cord around neck, with compression	0.022	0.977	0.000
K75.0 Abscess of liver	0.000	0.978	0.022
O69.5 Labour and delivery complicated by vascular lesion of cord	0.022	0.978	0.000
O69.4 Labour and delivery complicated by vasa praevia	0.022	0.978	0.000
O69.3 Labour and delivery complicated by short cord	0.022	0.978	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.022	0.978	0.000
C67.4 Posterior wall of bladder	0.000	0.978	0.022
C67.2 Lateral wall of bladder	0.000	0.978	0.022
O73.1 Retained portions of placenta and membranes, without haemorrhage	0.022	0.978	0.000
K71.9 Toxic liver disease, unspecified	0.000	0.978	0.022
K71.8 Toxic liver disease with other disorders of liver	0.000	0.978	0.022
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.978	0.022
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.978	0.022
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.978	0.022
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.978	0.022
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.978	0.022
K71.2 Toxic liver disease with acute hepatitis	0.000	0.978	0.022
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.978	0.022
K71.0 Toxic liver disease with cholestasis	0.000	0.978	0.022
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.978	0.022
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.978	0.022
K73.9 Chronic hepatitis, unspecified	0.000	0.978	0.021
K76.9 Liver disease, unspecified	0.000	0.978	0.022
O71.4 Obstetric high vaginal laceration alone	0.021	0.979	0.000
D12.9 Anus and anal canal	0.021	0.979	0.000
C67.6 Ureteric orifice	0.000	0.979	0.021
O66.9 Obstructed labour, unspecified	0.021	0.979	0.000
O66.8 Other specified obstructed labour	0.021	0.979	0.000
O66.4 Failed trial of labour, unspecified	0.021	0.979	0.000
O66.3 Obstructed labour due to other abnormalities of foetus	0.021	0.979	0.000
O66.2 Obstructed labour due to unusually large foetus	0.021	0.979	0.000
O66.1 Obstructed labour due to locked twins	0.021	0.979	0.000
D12.2 Ascending colon	0.021	0.979	0.000
O71.9 Obstetric trauma, unspecified	0.021	0.979	0.000
O71.8 Other specified obstetric trauma	0.021	0.979	0.000
O71.7 Obstetric haematoma of pelvis	0.021	0.979	0.000
O71.6 Obstetric damage to pelvic joints and ligaments	0.021	0.979	0.000
O71.5 Other obstetric injury to pelvic organs	0.021	0.979	0.000
O71.3 Obstetric laceration of cervix	0.021	0.979	0.000
O71.2 Postpartum inversion of uterus	0.021	0.979	0.000
O71.1 Rupture of uterus during labour	0.021	0.979	0.000
O71.0 Rupture of uterus before onset of labour	0.021	0.979	0.000
O72.0 Third-stage haemorrhage	0.021	0.979	0.000
O60.3 Preterm delivery without spontaneous labour	0.021	0.979	0.000
O60.2 Preterm spontaneous labour with term delivery	0.021	0.979	0.000
O60.1 Preterm spontaneous labour with preterm delivery	0.021	0.979	0.000
O60.0 Preterm labour without delivery	0.021	0.979	0.000
O65.9 Obstructed labour due to maternal pelvic abnormality, unspecified	0.021	0.979	0.000
O65.8 Obstructed labour due to other maternal pelvic abnormalities	0.021	0.979	0.000
O65.5 Obstructed labour due to abnormality of maternal pelvic organs	0.021	0.979	0.000
O65.4 Obstructed labour due to foetopelvic disproportion, unspecified	0.021	0.979	0.000
O65.3 Obstructed labour due to pelvic outlet and midcavity contraction	0.021	0.979	0.000
O65.2 Obstructed labour due to pelvic inlet contraction	0.021	0.979	0.000
O65.1 Obstructed labour due to generally contracted pelvis	0.021	0.979	0.000
O65.0 Obstructed labour due to deformed pelvis	0.021	0.979	0.000
O74.9 Complication of anaesthesia during labour and delivery, unspecified	0.021	0.979	0.000
O74.8 Other complications of anaesthesia during labour and delivery	0.021	0.979	0.000
O74.7 Failed or difficult intubation during labour and delivery	0.021	0.979	0.000
O74.6 Other complications of spinal and epidural anaesthesia during labour and delivery	0.021	0.979	0.000
O74.5 Spinal and epidural anaesthesia-induced headache during labour and delivery	0.021	0.979	0.000
O74.4 Toxic reaction to local anaesthesia during labour and delivery	0.021	0.979	0.000
O74.3 Central nervous system complications of anaesthesia during labour and delivery	0.021	0.979	0.000
O74.2 Cardiac complications of anaesthesia during labour and delivery	0.021	0.979	0.000
O74.1 Other pulmonary complications of anaesthesia during labour and delivery	0.021	0.979	0.000
O74.0 Aspiration pneumonitis due to anaesthesia during labour and delivery	0.021	0.979	0.000
Q21.1 Atrial septal defect	0.021	0.979	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.021	0.979	0.000
O64.5 Obstructed labour due to compound presentation	0.021	0.979	0.000
O64.4 Obstructed labour due to shoulder presentation	0.021	0.979	0.000
O64.3 Obstructed labour due to brow presentation	0.021	0.979	0.000
O64.2 Obstructed labour due to face presentation	0.021	0.979	0.000
I11 Hypertensive heart disease	0.021	0.979	0.000
D12.3 Transverse colon	0.021	0.979	0.000
D12.8 Rectum	0.021	0.979	0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.020	0.980	0.000
O63 Long labour	0.020	0.980	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.980	0.020
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.980	0.020
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.980	0.020
O66.0 Obstructed labour due to shoulder dystocia	0.020	0.980	0.000
O72.3 Postpartum coagulation defects	0.019	0.980	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.019	0.981	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.019	0.981	0.000
O67.8 Other intrapartum haemorrhage	0.019	0.981	0.000
O67.0 Intrapartum haemorrhage with coagulation defect	0.019	0.981	0.000
Y40.0 Penicillins	0.019	0.981	0.000
Q21 Congenital malformations of cardiac septa	0.019	0.981	0.000
C67.8 Overlapping lesion of bladder	0.000	0.981	0.019
C67.7 Urachus	0.000	0.981	0.019
C67.5 Bladder neck	0.000	0.981	0.019
C67.3 Anterior wall of bladder	0.000	0.981	0.019
C67.1 Dome of bladder	0.000	0.981	0.019
C67.0 Trigone of bladder	0.000	0.981	0.019
O70 Perineal laceration during delivery	0.016	0.981	0.002
K70.3 Alcoholic cirrhosis of liver	0.000	0.982	0.018
I11.9 Hypertensive heart disease without (congestive) heart failure	0.018	0.982	0.000
O61.9 Failed induction of labour, unspecified	0.018	0.982	0.000
O61.8 Other failed induction of labour	0.018	0.982	0.000
O61.1 Failed instrumental induction of labour	0.018	0.982	0.000
I13 Hypertensive heart and renal disease	0.018	0.982	0.000
O64.1 Obstructed labour due to breech presentation	0.017	0.982	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.017	0.983	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.983	0.017
O67.9 Intrapartum haemorrhage, unspecified	0.016	0.983	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.016	0.983	0.001
K70.4 Alcoholic hepatic failure	0.000	0.983	0.016
I15 Secondary hypertension	0.016	0.983	0.000
K70.0 Alcoholic fatty liver	0.000	0.984	0.016
D12.7 Rectosigmoid junction	0.016	0.984	0.000
O70.2 Third degree perineal laceration during delivery	0.015	0.984	0.001
Q28 Other congenital malformations of circulatory system	0.015	0.985	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.015	0.985	0.000
O72.1 Other immediate postpartum haemorrhage	0.015	0.985	0.000
O63.9 Long labour, unspecified	0.015	0.985	0.000
O63.2 Delayed delivery of second twin, triplet, etc.	0.015	0.985	0.000
Q21.0 Ventricular septal defect	0.015	0.985	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.014	0.985	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.001	0.986	0.014
Q28.2 Arteriovenous malformation of cerebral vessels	0.014	0.986	0.000
O61.0 Failed medical induction of labour	0.014	0.986	0.000
Q27 Other congenital malformations of peripheral vascular system	0.014	0.986	0.000
Q25 Congenital malformations of great arteries	0.014	0.986	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.014	0.986	0.000
Q21.8 Other congenital malformations of cardiac septa	0.014	0.986	0.000
Q21.4 Aortopulmonary septal defect	0.014	0.986	0.000
Q21.3 Tetralogy of Fallot	0.014	0.986	0.000
Q21.2 Atrioventricular septal defect	0.014	0.986	0.000
Q24 Other congenital malformations of heart	0.014	0.986	0.000
K70.1 Alcoholic hepatitis	0.000	0.986	0.013
O70.3 Fourth degree perineal laceration during delivery	0.012	0.986	0.002
Y42.1 Thyroid hormones and substitutes	0.013	0.986	0.001
O63.0 Prolonged first stage (of labour)	0.013	0.987	0.000
O70.9 Perineal laceration during delivery, unspecified	0.011	0.987	0.002
I13.9 Hypertensive heart and renal disease, unspecified	0.013	0.987	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.013	0.987	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.013	0.987	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.013	0.987	0.000
K70.9 Alcoholic liver disease, unspecified	0.000	0.987	0.013
Q26 Congenital malformations of great veins	0.012	0.988	0.000
Q22 Congenital malformations of pulmonary and tricuspid valves	0.012	0.988	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.012	0.988	0.000
Y42.9 Other and unspecified hormone antagonists	0.011	0.988	0.001
Y42.4 Oral contraceptives	0.011	0.988	0.001
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.011	0.988	0.001
Y42.2 Antithyroid drugs	0.011	0.988	0.001
I15.9 Seconday hypertension, unspecified	0.012	0.988	0.000
I15.8 Other secondary hypertension	0.012	0.988	0.000
I15.2 Hypertension secondary to endocrine disorders	0.012	0.988	0.000
I15.0 Renovascular hypertension	0.012	0.988	0.000
Q23 Congenital malformations of aortic and mitral valves	0.012	0.988	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.011	0.988	0.001
Q27.3 Peripheral arteriovenous malformation	0.012	0.988	0.000
Q25.4 Other congenital malformations of aorta	0.011	0.988	0.000
Q24.8 Other specified congenital malformations of heart	0.011	0.989	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.011	0.989	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.011	0.989	0.000
Q28.3 Other malformations of cerebral vessels	0.011	0.989	0.000
Q28.1 Other malformations of precerebral vessels	0.011	0.989	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.011	0.989	0.000
K20 Oesophagitis	0.011	0.989	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.010	0.989	0.001
I15.1 Hypertension secondary to other renal disorders	0.011	0.989	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.010	0.990	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.010	0.990	0.000
Q27.4 Congenital phlebectasia	0.010	0.990	0.000
Q27.2 Other congenital malformations of renal artery	0.010	0.990	0.000
Q27.1 Congenital renal artery stenosis	0.010	0.990	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.010	0.990	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.010	0.990	0.000
Q25.8 Other congenital malformations of great arteries	0.010	0.990	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.010	0.990	0.000
Q25.6 Stenosis of pulmonary artery	0.010	0.990	0.000
Q25.5 Atresia of pulmonary artery	0.010	0.990	0.000
Q25.3 Stenosis of aorta	0.010	0.990	0.000
Q25.2 Atresia of aorta	0.010	0.990	0.000
Q25.1 Coarctation of aorta	0.010	0.990	0.000
Q25.0 Patent ductus arteriosus	0.010	0.990	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.010	0.990	0.000
Q24.6 Congenital heart block	0.010	0.990	0.000
Q24.5 Malformation of coronary vessels	0.010	0.990	0.000
Q24.4 Congenital subaortic stenosis	0.010	0.990	0.000
Q24.3 Pulmonary infundibular stenosis	0.010	0.990	0.000
Q24.2 Cor triatriatum	0.010	0.990	0.000
Q24.1 Levocardia	0.010	0.990	0.000
Q24.0 Dextrocardia	0.010	0.990	0.000
Y42.7 Androgens and anabolic congeners	0.009	0.990	0.001
Z42.1 Follow-up care involving plastic surgery of breast	0.010	0.990	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.009	0.990	0.001
I12 Hypertensive renal disease	0.009	0.990	0.000
Z85.5 Personal history of malignant neoplasm of urinary tract	0.000	0.991	0.009
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.009	0.991	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.009	0.991	0.000
Q20.6 Isomerism of atrial appendages	0.009	0.991	0.000
Q20.5 Discordant atrioventricular connexion	0.009	0.991	0.000
Q20.4 Double inlet ventricle	0.009	0.991	0.000
Q20.3 Discordant ventriculoarterial connexion	0.009	0.991	0.000
Q20.2 Double outlet left ventricle	0.009	0.991	0.000
Q20.1 Double outlet right ventricle	0.009	0.991	0.000
Q20.0 Common arterial trunk	0.009	0.991	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.009	0.991	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.009	0.991	0.000
Q22.6 Hypoplastic right heart syndrome	0.009	0.991	0.000
Q22.5 Ebstein's anomaly	0.009	0.991	0.000
Q22.4 Congenital tricuspid stenosis	0.009	0.991	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.009	0.991	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.009	0.991	0.000
Q22.1 Congenital pulmonary valve stenosis	0.009	0.991	0.000
Q22.0 Pulmonary valve atresia	0.009	0.991	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.009	0.991	0.000
Q26.8 Other congenital malformations of great veins	0.009	0.991	0.000
Q26.6 Portal vein-hepatic artery fistula	0.009	0.991	0.000
Q26.5 Anomalous portal venous connexion	0.009	0.991	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.009	0.991	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.009	0.991	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.009	0.991	0.000
Q26.1 Persistent left superior vena cava	0.009	0.991	0.000
Q26.0 Congenital stenosis of vena cava	0.009	0.991	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.991	0.009
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.009	0.991	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.009	0.991	0.000
Q23.4 Hypoplastic left heart syndrome	0.009	0.991	0.000
Q23.3 Congenital mitral insufficiency	0.009	0.991	0.000
Q23.2 Congenital mitral stenosis	0.009	0.991	0.000
Q23.0 Congenital stenosis of aortic valve	0.009	0.991	0.000
O63.1 Prolonged second stage (of labour)	0.009	0.991	0.000
Q23.1 Congenital insufficiency of aortic valve	0.008	0.991	0.000
C64-C68 Malignant neoplasms of urinary tract	0.000	0.992	0.008
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.007	0.993	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations