TreeWAS – Variant ID: rs11891

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M20.2 Hallux rigidus	0.020	0.980	0.000
R53 Malaise and fatigue	0.000	0.989	0.011
R56.8 Other and unspecified convulsions	0.000	0.991	0.009
C77.2 Intra-abdominal lymph nodes	0.000	0.993	0.007
M24 Other specific joint derangements	0.007	0.993	0.000
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.000	0.993	0.007
M20 Acquired deformities of fingers and toes	0.007	0.993	0.000
M24.1 Other articular cartilage disorders	0.006	0.993	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.006	0.994	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.006	0.994	0.000
K29.0 Acute haemorrhagic gastritis	0.006	0.994	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.006	0.994	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.006	0.994	0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.006	0.994	0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.006	0.994	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.005	0.994	0.000
M20.3 Other deformity of hallux (acquired)	0.005	0.995	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.995	0.005
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.005	0.995	0.000
M20-M25 Other joint disorders	0.005	0.995	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.005	0.995	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.005	0.995	0.000
M30 Polyarteritis nodosa and related conditions	0.005	0.995	0.000
M24.9 Joint derangement, unspecified	0.005	0.995	0.000
M24.7 Protrusio acetabuli	0.005	0.995	0.000
M24.6 Ankylosis of joint	0.005	0.995	0.000
M20.5 Other deformities of toe(s) (acquired)	0.005	0.995	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.005	0.995	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.995	0.005
M24.19 Other articular cartilage disorders (Site unspecified)	0.005	0.995	0.000
M24.18 Other articular cartilage disorders (Other)	0.005	0.995	0.000
M24.14 Other articular cartilage disorders (Hand)	0.005	0.995	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.005	0.995	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.005	0.995	0.000
M33 Dermatopolymyositis	0.005	0.995	0.000
M33.1 Other dermatomyositis	0.005	0.995	0.000
M21.16 Varus deformity, not elsewhere classified (Lower leg)	0.005	0.995	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.005	0.995	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.005	0.995	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.005	0.995	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.005	0.995	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.005	0.995	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.005	0.995	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.005	0.995	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.005	0.995	0.000
M24.5 Contracture of joint	0.005	0.995	0.000
M21 Other acquired deformities of limbs	0.005	0.995	0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]	0.005	0.995	0.000
I27.0 Primary pulmonary hypertension	0.005	0.995	0.000
M21.1 Varus deformity, not elsewhere classified	0.005	0.995	0.000
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.004	0.995	0.000
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.004	0.995	0.000
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.004	0.995	0.000
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.004	0.995	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.004	0.995	0.000
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.004	0.995	0.000
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.004	0.995	0.000
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.004	0.995	0.000
M24.2 Disorder of ligament	0.004	0.995	0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.004	0.996	0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.004	0.996	0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.004	0.996	0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.004	0.996	0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.004	0.996	0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.004	0.996	0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.004	0.996	0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.004	0.996	0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.004	0.996	0.000
M34 Systemic sclerosis	0.004	0.996	0.000
M30.0 Polyarteritis nodosa	0.004	0.996	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.996	0.004
M24.0 Loose body in joint	0.004	0.996	0.000
M31 Other necrotising vasculopathies	0.004	0.996	0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.004	0.996	0.000
M32 Systemic lupus erythematosus	0.004	0.996	0.000
M21.8 Other specified acquired deformities of limbs	0.004	0.996	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.996	0.004
M24.57 Contracture of joint (Ankle and foot)	0.004	0.996	0.000
M21.6 Other acquired deformities of ankle and foot	0.004	0.996	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.996	0.004
M31.7 Microscopic polyangiitis	0.004	0.996	0.000
M22 Disorders of patella	0.004	0.996	0.000
M30.8 Other conditions related to polyarteritis nodosa	0.004	0.996	0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]	0.004	0.996	0.000
M30.2 Juvenile polyarteritis	0.004	0.996	0.000
R56 Convulsions, not elsewhere classified	0.000	0.996	0.004
M24.69 Ankylosis of joint (Site unspecified)	0.004	0.996	0.000
M24.68 Ankylosis of joint (Other)	0.004	0.996	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.004	0.996	0.000
M24.66 Ankylosis of joint (Lower leg)	0.004	0.996	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.004	0.996	0.000
M24.64 Ankylosis of joint (Hand)	0.004	0.996	0.000
M24.63 Ankylosis of joint (Forearm)	0.004	0.996	0.000
M24.62 Ankylosis of joint (Upper arm)	0.004	0.996	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.004	0.996	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.004	0.996	0.000
M24.79 Protrusio acetabuli-Site unspec	0.004	0.996	0.000
M24.78 Protrusio acetabuli-Other	0.004	0.996	0.000
M24.77 Protrusio acetabuli-Ankle/foot	0.004	0.996	0.000
M24.76 Protrusio acetabuli-Lower leg	0.004	0.996	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.004	0.996	0.000
M24.74 Protrusio acetabuli-Hand	0.004	0.996	0.000
M24.73 Protrusio acetabuli-Forearm	0.004	0.996	0.000
M24.72 Protrusio acetabuli-Upper arm	0.004	0.996	0.000
M24.71 Protrusio acetabuli-Shldr region	0.004	0.996	0.000
M24.70 Protrusio acetabuli-Mult sites	0.004	0.996	0.000
M24.99 Joint derangement, unspecified (Site unspecified)	0.004	0.996	0.000
M24.98 Joint derangement, unspecified (Other)	0.004	0.996	0.000
M24.97 Joint derangement, unspecified (Ankle and foot)	0.004	0.996	0.000
M24.96 Joint derangement, unspecified (Lower leg)	0.004	0.996	0.000
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M24.94 Joint derangement, unspecified (Hand)	0.004	0.996	0.000
M24.93 Joint derangement, unspecified (Forearm)	0.004	0.996	0.000
M24.92 Joint derangement, unspecified (Upper arm)	0.004	0.996	0.000
M24.91 Joint derangement, unspecified (Shoulder region)	0.004	0.996	0.000
M24.90 Joint derangement, unspecified (Multiple sites)	0.004	0.996	0.000
M34.9 Systemic sclerosis, unspecified	0.004	0.996	0.000
M24.51 Contracture of joint (Shoulder region)	0.004	0.996	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.996	0.004
M33.9 Dermatopolymyositis, unspecified	0.004	0.996	0.000
M33.0 Juvenile dermatomyositis	0.004	0.996	0.000
M24.24 Disorder of ligament (Hand)	0.004	0.996	0.000
M21.85 Other specified acquired deformities of limbs (Pelvic region and thigh)	0.004	0.996	0.000
M24.59 Contracture of joint (Site unspecified)	0.003	0.996	0.000
M24.58 Contracture of joint (Other)	0.003	0.996	0.000
M24.56 Contracture of joint (Lower leg)	0.003	0.996	0.000
M24.55 Contracture of joint (Pelvic region and thigh)	0.003	0.996	0.000
M24.53 Contracture of joint (Forearm)	0.003	0.996	0.000
M24.52 Contracture of joint (Upper arm)	0.003	0.996	0.000
M24.50 Contracture of joint (Multiple sites)	0.003	0.996	0.000
M21.9 Acquired deformity of limb, unspecified	0.004	0.996	0.000
M21.7 Unequal limb length (acquired)	0.004	0.996	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.004	0.996	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.003	0.996	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.003	0.996	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.003	0.996	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.003	0.996	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.003	0.996	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.003	0.996	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.003	0.996	0.000
M81.98 Osteoporosis, unspecified (Other)	0.004	0.996	0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot	0.003	0.996	0.000
Z95.4 Presence of other heart-valve replacement	0.004	0.996	0.000
M34.8 Other forms of systemic sclerosis	0.003	0.996	0.000
M24.29 Disorder of ligament (Site unspecified)	0.003	0.996	0.000
M24.28 Disorder of ligament (Other)	0.003	0.996	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.003	0.996	0.000
M24.22 Disorder of ligament (Upper arm)	0.003	0.996	0.000
M24.21 Disorder of ligament (Shoulder region)	0.003	0.996	0.000
M24.20 Disorder of ligament (Multiple sites)	0.003	0.996	0.000
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.003	0.996	0.000
M33.2 Polymyositis	0.003	0.996	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.996	0.003
I12.0 Hypertensive renal disease with renal failure	0.003	0.997	0.000
M22.4 Chondromalacia patellae	0.003	0.997	0.000
M34.2 Systemic sclerosis induced by drugs and chemicals	0.003	0.997	0.000
M34.0 Progressive systemic sclerosis	0.003	0.997	0.000
M24.26 Disorder of ligament (Lower leg)	0.003	0.997	0.000
M21.2 Flexion deformity	0.003	0.997	0.000
C77.9 Lymph node, unspecified	0.000	0.997	0.003
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.997	0.003
M21.0 Valgus deformity, not elsewhere classified	0.003	0.997	0.000
M25.8 Other specified joint disorders	0.003	0.997	0.000
M24.09 Loose body in joint (Site unspecified)	0.003	0.997	0.000
M24.08 Loose body in joint (Other)	0.003	0.997	0.000
M24.06 Loose body in joint-Lower leg	0.003	0.997	0.000
M24.05 Loose body in joint (Pelvic region and thigh)	0.003	0.997	0.000
M24.04 Loose body in joint (Hand)	0.003	0.997	0.000
M24.03 Loose body in joint (Forearm)	0.003	0.997	0.000
M24.01 Loose body in joint (Shoulder region)	0.003	0.997	0.000
M24.00 Loose body in joint (Multiple sites)	0.003	0.997	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.003	0.997	0.000
M21.4 Flat foot [pes planus] (acquired)	0.003	0.997	0.000
M31.9 Necrotising vasculopathy, unspecified	0.003	0.997	0.000
M31.8 Other specified necrotising vasculopathies	0.003	0.997	0.000
M31.4 Aortic arch syndrome [Takayasu]	0.003	0.997	0.000
M31.2 Lethal midline granuloma	0.003	0.997	0.000
M31.1 Thrombotic microangiopathy	0.003	0.997	0.000
M31.0 Hypersensitivity angiitis	0.003	0.997	0.000
M32.9 Systemic lupus erythematosus, unspecified	0.003	0.997	0.000
M32.8 Other forms of systemic lupus erythematosus	0.003	0.997	0.000
M32.1 Systemic lupus erythematosus with organ or system involvement	0.003	0.997	0.000
M32.0 Drug-induced systemic lupus erythematosus	0.003	0.997	0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere	0.003	0.997	0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere	0.003	0.997	0.000
M36.3 Arthropathy in other blood disorders	0.003	0.997	0.000
M36.2 Haemophilic arthropathy	0.003	0.997	0.000
M36.1 Arthropathy in neoplastic disease	0.003	0.997	0.000
M36.0 Dermato(poly)myositis in neoplastic disease	0.003	0.997	0.000
M21.89 Other specified acquired deformities of limbs (Site unspecified)	0.003	0.997	0.000
M21.88 Other specified acquired deformities of limbs-Other	0.003	0.997	0.000
M21.87 Other specified acquired deformities of limbs (Ankle and foot)	0.003	0.997	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.003	0.997	0.000
M21.84 Other specified acquired deformities of limbs (Hand)	0.003	0.997	0.000
M21.83 Other specified acquired deformities of limbs (Forearm)	0.003	0.997	0.000
M21.82 Other specified acquired deformities of limbs (Upper arm)	0.003	0.997	0.000
M21.81 Other specified acquired deformities of limbs (Shoulder region)	0.003	0.997	0.000
M21.80 Other specified acquired deformities of limbs (Multiple sites)	0.003	0.997	0.000
M22.8 Other disorders of patella	0.003	0.997	0.000
M25 Other joint disorders, not elsewhere classified	0.003	0.997	0.000
M22.0 Recurrent dislocation of patella	0.003	0.997	0.000
M24.23 Disorder of ligament (Forearm)	0.003	0.997	0.000
M22.3 Other derangements of patella	0.003	0.997	0.000
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.003	0.997	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.003	0.997	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.003	0.997	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.003	0.997	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.003	0.997	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.003	0.997	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.003	0.997	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.003	0.997	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.003	0.997	0.000
M22.1 Recurrent subluxation of patella	0.003	0.997	0.000
M22.9 Disorder of patella, unspecified	0.003	0.997	0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.003	0.997	0.000
M21.3 Wrist or foot drop (acquired)	0.003	0.997	0.000
M34.1 CR(E)ST syndrome	0.003	0.997	0.000
M24.07 Loose body in joint (Ankle and foot)	0.003	0.997	0.000
R56.0 Febrile convulsions	0.000	0.997	0.003
C43.5 Malignant melanoma of trunk	0.000	0.997	0.003
M31.3 Wegener's granulomatosis	0.003	0.997	0.000
M21.79 Unequal limb length (acquired) (Site unspecified)	0.003	0.997	0.000
M21.78 Unequal limb length (acquired)-Other	0.003	0.997	0.000
M21.77 Unequal limb length (acquired) (Ankle and foot)	0.003	0.997	0.000
M21.76 Unequal limb length (acquired) (Lower leg)	0.003	0.997	0.000
M21.75 Unequal limb length (acquired) (Pelvic region and thigh)	0.003	0.997	0.000
M21.74 Unequal limb length (acquired) (Hand)	0.003	0.997	0.000
M21.73 Unequal limb length (acquired) (Forearm)	0.003	0.997	0.000
M21.72 Unequal limb length (acquired) (Upper arm)	0.003	0.997	0.000
M21.71 Unequal limb length (acquired)-Shldr region	0.003	0.997	0.000
M21.70 Unequal limb length (acquired) (Multiple sites)	0.003	0.997	0.000
M21.99 Acquired deformity of limb, unspecified (Site unspecified)	0.003	0.997	0.000
M21.98 Acquired deformity of limb, unspecified-Other	0.003	0.997	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.003	0.997	0.000
M21.96 Acquired deformity of limb, unspecified (Lower leg)	0.003	0.997	0.000
M21.95 Acquired deformity of limb, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M21.94 Acquired deformity of limb, unspecified (Hand)	0.003	0.997	0.000
M21.93 Acquired deformity of limb, unspecified (Forearm)	0.003	0.997	0.000
M21.92 Acquired deformity of limb, unspecified (Upper arm)	0.003	0.997	0.000
M21.91 Acquired deformity of limb, unspecified (Shoulder region)	0.003	0.997	0.000
M21.90 Acquired deformity of limb, unspecified (Multiple sites)	0.003	0.997	0.000
D22.5 Melanocytic naevi of trunk	0.000	0.997	0.003
M21.59 Acquired clawhand, clubhand, clawfoot and clubfoot-Site uns	0.003	0.997	0.000
M21.58 Acquired clawhand, clubhand, clawfoot and clubfoot-Other	0.003	0.997	0.000
M21.56 Acquired clawhand, clubhand, clawfoot and clubfoot-Lower le	0.003	0.997	0.000
M21.55 Acquired clawhand, clubhand, clawfoot and clubfoot-Pelvic/t	0.003	0.997	0.000
M21.54 Acquired clawhand, clubhand, clawfoot and clubfoot (Hand)	0.003	0.997	0.000
M21.53 Acquired clawhand, clubhand, clawfoot and clubfoot-Forearm	0.003	0.997	0.000
M21.52 Acquired clawhand, clubhand, clawfoot and clubfoot-Upper ar	0.003	0.997	0.000
M21.51 Acquired clawhand, clubhand, clawfoot and clubfoot-Shldr re	0.003	0.997	0.000
M21.50 Acquired clawhand, clubhand, clawfoot and clubfoot (Multiple sites)	0.003	0.997	0.000
K65.0 Acute peritonitis	0.003	0.997	0.000
M21.24 Flexion deformity (Hand)	0.003	0.997	0.000
M25.74 Osteophyte (Hand)	0.003	0.997	0.000
F32.1 Moderate depressive episode	0.003	0.997	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.003	0.997	0.000
M25.84 Other specified joint disorders (Hand)	0.003	0.997	0.000
M24.54 Contracture of joint (Hand)	0.002	0.997	0.001
M25.3 Other instability of joint	0.003	0.997	0.000
M21.29 Flexion deformity (Site unspecified)	0.003	0.997	0.000
M21.28 Flexion deformity (Other)	0.003	0.997	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.003	0.997	0.000
M21.23 Flexion deformity (Forearm)	0.003	0.997	0.000
M21.22 Flexion deformity (Upper arm)	0.003	0.997	0.000
M21.21 Flexion deformity (Shoulder region)	0.003	0.997	0.000
M21.20 Flexion deformity (Multiple sites)	0.003	0.997	0.000
M25.87 Other specified joint disorders (Ankle and foot)	0.003	0.997	0.000
K65.9 Peritonitis, unspecified	0.003	0.997	0.000
M21.09 Valgus deformity, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M21.08 Valgus deformity, not elsewhere classified (Other)	0.002	0.997	0.000
M21.05 Valgus deformity, not elsewhere classified (Pelvic region and thigh)	0.002	0.997	0.000
M21.04 Valgus deformity, not elsewhere classified (Hand)	0.002	0.997	0.000
M21.03 Valgus deformity, not elsewhere classified (Forearm)	0.002	0.997	0.000
M21.02 Valgus deformity, not elsewhere classified (Upper arm)	0.002	0.997	0.000
M21.01 Valgus deformity, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
M21.00 Valgus deformity, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
M24.02 Loose body in joint (Upper arm)	0.002	0.997	0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)	0.003	0.997	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.997	0.000
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.997	0.000
M25.89 Other specified joint disorders (Site unspecified)	0.003	0.997	0.000
M25.88 Other specified joint disorders (Other)	0.003	0.997	0.000
M25.83 Other specified joint disorders (Forearm)	0.003	0.997	0.000
M25.82 Other specified joint disorders (Upper arm)	0.003	0.997	0.000
M25.80 Other specified joint disorders (Multiple sites)	0.003	0.997	0.000
M18 Arthrosis of first carpometacarpal joint	0.000	0.997	0.003
M21.49 Flat foot [pes planus] (acquired)-Site unspec	0.002	0.997	0.000
M21.48 Flat foot [pes planus] (acquired)-Other	0.002	0.997	0.000
M21.46 Flat foot [pes planus] (acquired)-Lower leg	0.002	0.997	0.000
M21.45 Flat foot [pes planus] (acquired)-Pelvic/thigh	0.002	0.997	0.000
M21.44 Flat foot [pes planus] (acquired)-Hand	0.002	0.997	0.000
M21.43 Flat foot [pes planus] (acquired)-Forearm	0.002	0.997	0.000
M21.42 Flat foot [pes planus] (acquired)-Upper arm	0.002	0.997	0.000
M21.41 Flat foot [pes planus] (acquired)-Shldr region	0.002	0.997	0.000
M21.40 Flat foot [pes planus] (acquired)-Mult sites	0.002	0.997	0.000
M32.90 Systemic lupus erythematosus, unspecified, Multiple sites	0.002	0.997	0.000
M22.2 Patellofemoral disorders	0.001	0.997	0.002
M25.2 Flail joint	0.002	0.997	0.000
M25.1 Fistula of joint	0.002	0.997	0.000
M20.0 Deformity of finger(s)	0.002	0.997	0.001
S80.9 Superficial injury of lower leg, unspecified	0.003	0.997	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.997	0.000
M31.6 Other giant cell arteritis	0.002	0.997	0.000
M22.10 Recurrent subluxation of patella, unspecified knee	0.002	0.997	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.002	0.997	0.000
M21.38 Wrist or foot drop (acquired)-Other	0.002	0.997	0.000
M21.36 Wrist or foot drop (acquired)-Lower leg	0.002	0.997	0.000
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.002	0.997	0.000
M21.34 Wrist or foot drop (acquired) (Hand)	0.002	0.997	0.000
M21.33 Wrist or foot drop (acquired) (Forearm)	0.002	0.997	0.000
M21.32 Wrist or foot drop (acquired)-Upper arm	0.002	0.997	0.000
M21.31 Wrist or foot drop (acquired)-Shldr region	0.002	0.997	0.000
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.002	0.997	0.000
M19.94 Arthrosis, unspecified (Hand)	0.000	0.997	0.003
M25.0 Haemarthrosis	0.002	0.997	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
M25.7 Osteophyte	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
M25.36 Other instability of joint (Lower leg)	0.002	0.998	0.000
K65 Peritonitis	0.002	0.998	0.000
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
I27 Other pulmonary heart diseases	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.002	0.998	0.000
M35 Other systemic involvement of connective tissue	0.002	0.998	0.000
J84 Other interstitial pulmonary diseases	0.000	0.998	0.002
M20.1 Hallux valgus (acquired)	0.002	0.998	0.000
M25.9 Joint disorder, unspecified	0.002	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.002	0.998	0.000
M25.37 Other instability of joint (Ankle and foot)	0.002	0.998	0.000
C43 Malignant melanoma of skin	0.000	0.998	0.002
N18.9 Chronic renal failure, unspecified	0.002	0.998	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
M25.39 Other instability of joint (Site unspecified)	0.002	0.998	0.000
M25.38 Other instability of joint (Other)	0.002	0.998	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.34 Other instability of joint (Hand)	0.002	0.998	0.000
M25.33 Other instability of joint (Forearm)	0.002	0.998	0.000
M25.32 Other instability of joint (Upper arm)	0.002	0.998	0.000
M25.30 Other instability of joint (Multiple sites)	0.002	0.998	0.000
C43.4 Malignant melanoma of scalp and neck	0.000	0.998	0.002
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M21.47 Flat foot [pes planus] (acquired)-Ankle/foot	0.002	0.998	0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint	0.000	0.998	0.002
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral	0.000	0.998	0.002
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.998	0.002
N18.3 Chronic kidney disease, stage 3	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
M25.19 Fistula of joint (Site unspecified)	0.002	0.998	0.000
M25.18 Fistula of joint (Other)	0.002	0.998	0.000
M25.17 Fistula of joint (Ankle and foot)	0.002	0.998	0.000
M25.16 Fistula of joint (Lower leg)	0.002	0.998	0.000
M25.15 Fistula of joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.14 Fistula of joint (Hand)	0.002	0.998	0.000
M25.13 Fistula of joint (Forearm)	0.002	0.998	0.000
M25.12 Fistula of joint (Upper arm)	0.002	0.998	0.000
M25.11 Fistula of joint (Shoulder region)	0.002	0.998	0.000
M25.10 Fistula of joint (Multiple sites)	0.002	0.998	0.000
M25.29 Flail joint (Site unspecified)	0.002	0.998	0.000
M25.28 Flail joint (Other)	0.002	0.998	0.000
M25.27 Flail joint (Ankle and foot)	0.002	0.998	0.000
M25.26 Flail joint (Lower leg)	0.002	0.998	0.000
M25.25 Flail joint (Pelvic region and thigh)	0.002	0.998	0.000
M25.24 Flail joint (Hand)	0.002	0.998	0.000
M25.23 Flail joint (Forearm)	0.002	0.998	0.000
M25.22 Flail joint (Upper arm)	0.002	0.998	0.000
M25.21 Flail joint (Shoulder region)	0.002	0.998	0.000
M25.20 Flail joint (Multiple sites)	0.002	0.998	0.000
I25.8 Other forms of chronic ischaemic heart disease	0.002	0.998	0.000
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
R33 Retention of urine	0.002	0.998	0.000
S52.00 Fracture of upper end of ulna (closed)	0.000	0.998	0.002
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
M25.75 Osteophyte (Pelvic region and thigh)	0.002	0.998	0.000
C77.3 Axillary and upper limb lymph nodes	0.000	0.998	0.002
K65.8 Other peritonitis	0.002	0.998	0.000
M25.31 Other instability of joint (Shoulder region)	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.002	0.998	0.000
M25.09 Haemarthrosis (Site unspecified)	0.002	0.998	0.000
M25.08 Haemarthrosis (Other)	0.002	0.998	0.000
M25.07 Haemarthrosis (Ankle and foot)	0.002	0.998	0.000
M25.05 Haemarthrosis (Pelvic region and thigh)	0.002	0.998	0.000
M25.04 Haemarthrosis (Hand)	0.002	0.998	0.000
M25.03 Haemarthrosis (Forearm)	0.002	0.998	0.000
M25.02 Haemarthrosis (Upper arm)	0.002	0.998	0.000
M25.01 Haemarthrosis (Shoulder region)	0.002	0.998	0.000
M25.00 Haemarthrosis (Multiple sites)	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.002	0.998	0.000
M25.79 Osteophyte (Site unspecified)	0.002	0.998	0.000
M25.73 Osteophyte (Forearm)	0.002	0.998	0.000
M25.70 Osteophyte (Multiple sites)	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.002	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.002	0.998	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.002	0.998	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.998	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.998	0.000
M25.4 Effusion of joint	0.002	0.998	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.998	0.002
M35.9 Systemic involvement of connective tissue, unspecified	0.002	0.998	0.000
M35.8 Other specified systemic involvement of connective tissue	0.002	0.998	0.000
M35.6 Relapsing panniculitis [Weber-Christian]	0.002	0.998	0.000
M35.5 Multifocal fibrosclerosis	0.002	0.998	0.000
M35.4 Diffuse (eosinophilic) fasciitis	0.002	0.998	0.000
M35.2 Behcet's disease	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
M25.78 Osteophyte (Other)	0.002	0.998	0.000
M25.71 Osteophyte (Shoulder region)	0.002	0.998	0.000
J84.0 Alveolar and parietoalveolar conditions	0.000	0.998	0.002
N18 Chronic renal failure	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.002	0.998	0.000
M25.98 Joint disorder, unspecified (Other)	0.002	0.998	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.002	0.998	0.000
M25.94 Joint disorder, unspecified (Hand)	0.002	0.998	0.000
M25.93 Joint disorder, unspecified (Forearm)	0.002	0.998	0.000
M25.92 Joint disorder, unspecified (Upper arm)	0.002	0.998	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.002	0.998	0.000
M25.90 Joint disorder, unspecified (Multiple sites)	0.002	0.998	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
C43.8 Overlapping malignant melanoma of skin	0.000	0.998	0.002
C43.2 Malignant melanoma of ear and external auricular canal	0.000	0.998	0.002
C43.1 Malignant melanoma of eyelid, including canthus	0.000	0.998	0.002
C43.0 Malignant melanoma of lip	0.000	0.998	0.002
M35.1 Other overlap syndromes	0.002	0.998	0.000
M25.06 Haemarthrosis (Lower leg)	0.002	0.998	0.000
F20.9 Schizophrenia, unspecified	0.000	0.998	0.002
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
D68.2 Hereditary deficiency of other clotting factors	0.002	0.998	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.998	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.998	0.002
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M18.1 Other primary arthrosis of first carpometacarpal joint	0.000	0.998	0.002
N18.2 Chronic kidney disease, stage 2	0.002	0.998	0.000
C43.9 Malignant melanoma of skin, unspecified	0.000	0.998	0.002
M35.0 Sicca syndrome [Sjogren]	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.002	0.998	0.000
N18.1 Chronic kidney disease, stage 1	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
M25.42 Effusion of joint (Upper arm)	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
E11.4 With neurological complications	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.002	0.998	0.000
K38.8 Other specified diseases of appendix	0.002	0.998	0.000
M25.49 Effusion of joint (Site unspecified)	0.002	0.998	0.000
M25.48 Effusion of joint (Other)	0.002	0.998	0.000
M25.44 Effusion of joint (Hand)	0.002	0.998	0.000
M25.43 Effusion of joint (Forearm)	0.002	0.998	0.000
M25.41 Effusion of joint (Shoulder region)	0.002	0.998	0.000
M25.72 Osteophyte (Upper arm)	0.002	0.998	0.000
M25.40 Effusion of joint (Multiple sites)	0.002	0.998	0.000
M25.50 Pain in joint (Multiple sites)	0.002	0.998	0.000
M35.99 Systemic involvement of connective tissue, unspecified, Site unspecified	0.001	0.998	0.000
E11.5 With peripheral circulatory complications	0.002	0.998	0.000
M25.96 Joint disorder, unspecified (Lower leg)	0.001	0.998	0.000
Z00.0 General medical examination	0.000	0.998	0.002
M35.7 Hypermobility syndrome	0.001	0.998	0.000
M25.45 Effusion of joint (Pelvic region and thigh)	0.001	0.998	0.000
H81.0 Meniere's disease	0.000	0.998	0.002
M25.47 Effusion of joint (Ankle and foot)	0.002	0.998	0.000
E11.2 With renal complications	0.002	0.998	0.000
I27.2 Other secondary pulmonary hypertension	0.002	0.998	0.000
R29.6 Tendency to fall, not elsewhere classified	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.001	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
N18.8 Other chronic renal failure	0.001	0.998	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.001	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.998	0.001
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
R61.9 Hyperhidrosis, unspecified	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.001	0.998	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.000	0.999	0.001
I67.8 Other specified cerebrovascular diseases	0.001	0.999	0.000
I86.1 Scrotal varices	0.000	0.999	0.001
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.000	0.999	0.001
I46.9 Cardiac arrest, unspecified	0.000	0.999	0.001
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations