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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11891674
log Bayes Factor = 5.24113
Chromosome 2   position 40,281,964  (GRCh37) Explore rs11891674 on Ensembl!
Variant rs11891674 is part of Cluster X0160

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
M80-M85 Disorders of bone density and structure
0.999 0.001 0.000
M81 Osteoporosis without pathological fracture
0.999 0.001 0.000
M81.9 Osteoporosis, unspecified
0.998 0.002 0.000
M50-M54 Other dorsopathies
0.998 0.002 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.998 0.002 0.000
M25 Other joint disorders, not elsewhere classified
0.997 0.003 0.000
M45-M49 Spondylopathies
0.995 0.005 0.000
M50 Cervical disk disorders
0.989 0.011 0.000
M48 Other spondylopathies
0.983 0.017 0.000
M25.4 Effusion of joint
0.974 0.026 0.000
M23 Internal derangement of knee
0.963 0.037 0.000
M50.1 Cervical disk disorder with radiculopathy
0.960 0.040 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.960 0.040 0.000
M25.5 Pain in joint
0.960 0.040 0.000
M51 Other intervertebral disk disorders
0.959 0.041 0.000
M25.51 Pain in joint (Shoulder region)
0.955 0.045 0.000
M51.2 Other specified intervertebral disk displacement
0.952 0.048 0.000
M24 Other specific joint derangements
0.952 0.048 0.000
M25.47 Effusion of joint (Ankle and foot)
0.945 0.055 0.000
M40-M43 Deforming dorsopathies
0.930 0.070 0.000
M23.3 Other meniscus derangements
0.922 0.078 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.892 0.108 0.000
M48.0 Spinal stenosis
0.883 0.117 0.000
M23.8 Other internal derangements of knee
0.879 0.121 0.000
M80 Osteoporosis with pathological fracture
0.869 0.131 0.000
M47 Spondylosis
0.866 0.134 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.864 0.136 0.000
M23.4 Loose body in knee
0.850 0.150 0.000
M33 Dermatopolymyositis
0.847 0.153 0.000
M25.8 Other specified joint disorders
0.846 0.154 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.843 0.157 0.000
M30 Polyarteritis nodosa and related conditions
0.841 0.159 0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.839 0.161 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.837 0.163 0.000
M24.2 Disorder of ligament
0.833 0.167 0.000
M41 Scoliosis
0.832 0.168 0.000
M50.8 Other cervical disk disorders
0.830 0.170 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.822 0.178 0.000
M50.3 Other cervical disk degeneration
0.822 0.178 0.000
M81.98 Osteoporosis, unspecified (Other)
0.820 0.180 0.000
M50.9 Cervical disk disorder, unspecified
0.816 0.184 0.000
M48.09 Spinal stenosis (Site unspecified)
0.810 0.190 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.808 0.192 0.000
M00-M03 Infectious arthropathies
0.805 0.195 0.000
M47.9 Spondylosis, unspecified
0.798 0.202 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.795 0.205 0.000
M34 Systemic sclerosis
0.794 0.206 0.000
M81.0 Postmenopausal osteoporosis
0.792 0.208 0.000
M25.84 Other specified joint disorders (Hand)
0.789 0.211 0.000
M25.52 Pain in joint (Upper arm)
0.786 0.213 0.000
M70-M79 Other soft tissue disorders
0.773 0.227 0.000
M46 Other inflammatory spondylopathies
0.770 0.230 0.000
M23.49 Loose body in knee-Unspec lig/men
0.768 0.232 0.000
M84 Disorders of continuity of bone
0.768 0.232 0.000
M25.59 Pain in joint (Site unspecified)
0.767 0.233 0.000
M24.0 Loose body in joint
0.766 0.234 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.764 0.236 0.000
M23.0 Cystic meniscus
0.761 0.239 0.000
M48.02 Spinal stenosis (Cervical region)
0.759 0.241 0.000
M25.42 Effusion of joint (Upper arm)
0.758 0.242 0.000
M43 Other deforming dorsopathies
0.757 0.243 0.000
M41.9 Scoliosis, unspecified
0.753 0.247 0.000
M25.58 Pain in joint (Other)
0.753 0.247 0.000
M51.3 Other specified intervertebral disk degeneration
0.751 0.249 0.000
M32 Systemic lupus erythematosus
0.746 0.254 0.000
M45 Ankylosing spondylitis
0.745 0.255 0.000
M49 Spondylopathies in diseases classified elsewhere
0.743 0.257 0.000
M33.2 Polymyositis
0.739 0.261 0.000
M25.44 Effusion of joint (Hand)
0.739 0.261 0.000
M25.0 Haemarthrosis
0.737 0.263 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.733 0.267 0.000
M25.45 Effusion of joint (Pelvic region and thigh)
0.731 0.268 0.000
M80.9 Unspecified osteoporosis with pathological fracture
0.731 0.269 0.000
M30.1 Polyarteritis with lung involvement [Churg-Strauss]
0.727 0.273 0.000
M24.5 Contracture of joint
0.726 0.274 0.000
M25.57 Pain in joint (Ankle and foot)
0.725 0.275 0.000
M40 Kyphosis and lordosis
0.724 0.276 0.000
M23.1 Discoid meniscus (congenital)
0.721 0.279 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.718 0.282 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M83 Adult osteomalacia
0.716 0.283 0.000
M81.8 Other osteoporosis
0.716 0.284 0.000
M81.6 Localised osteoporosis [Lequesne]
0.716 0.284 0.000
M81.5 Idiopathic osteoporosis
0.716 0.284 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.716 0.284 0.000
M81.1 Postoophorectomy osteoporosis
0.716 0.284 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.716 0.284 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.716 0.284 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.716 0.284 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.716 0.284 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.716 0.284 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.716 0.284 0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)
0.715 0.285 0.000
M25.2 Flail joint
0.715 0.285 0.000
M25.1 Fistula of joint
0.715 0.285 0.000
M24.6 Ankylosis of joint
0.715 0.285 0.000
M24.24 Disorder of ligament (Hand)
0.714 0.286 0.000
M51.4 Schmorl's nodes
0.713 0.287 0.000
M25.46 Effusion of joint (Lower leg)
0.708 0.292 0.000
M65-M68 Disorders of synovium and tendon
0.707 0.293 0.000
M47.1 Other spondylosis with myelopathy
0.707 0.293 0.000
M31 Other necrotising vasculopathies
0.706 0.294 0.000
M48.9 Spondylopathy, unspecified
0.705 0.295 0.000
M48.8 Other specified spondylopathies
0.705 0.295 0.000
M48.4 Fatigue fracture of vertebra
0.705 0.295 0.000
M48.3 Traumatic spondylopathy
0.705 0.295 0.000
M48.2 Kissing spine
0.705 0.295 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.705 0.295 0.000
M81.2 Osteoporosis of disuse
0.704 0.296 0.000
M50.2 Other cervical disk displacement
0.702 0.298 0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)
0.701 0.299 0.000
M25.49 Effusion of joint (Site unspecified)
0.698 0.301 0.000
M25.48 Effusion of joint (Other)
0.698 0.301 0.000
M25.43 Effusion of joint (Forearm)
0.698 0.301 0.000
M25.41 Effusion of joint (Shoulder region)
0.698 0.301 0.000
M25.40 Effusion of joint (Multiple sites)
0.698 0.301 0.000
M79.0 Rheumatism, unspecified
0.697 0.303 0.000
M25.9 Joint disorder, unspecified
0.696 0.304 0.000
M54 Dorsalgia
0.696 0.304 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.695 0.305 0.000
M25.3 Other instability of joint
0.695 0.305 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.694 0.306 0.000
M85 Other disorders of bone density and structure
0.692 0.308 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.690 0.310 0.000
M53 Other dorsopathies, not elsewhere classified
0.688 0.312 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.688 0.312 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.688 0.312 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.688 0.312 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.688 0.312 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.688 0.312 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.688 0.312 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.688 0.312 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.687 0.313 0.000
M50.0 Cervical disk disorder with myelopathy
0.686 0.313 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.683 0.317 0.000
M24.9 Joint derangement, unspecified
0.682 0.318 0.000
M24.7 Protrusio acetabuli
0.682 0.318 0.000
M80.5 Idiopathic osteoporosis with pathological fracture
0.681 0.319 0.000
M24.26 Disorder of ligament (Lower leg)
0.679 0.321 0.000
M48.04 Spinal stenosis (Thoracic region)
0.678 0.322 0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)
0.677 0.323 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.676 0.324 0.000
M81.4 Drug-induced osteoporosis
0.676 0.324 0.000
M21 Other acquired deformities of limbs
0.674 0.326 0.000
M23.86 Other internal derangements of knee (Other and unspecified lateral meniscus)
0.671 0.328 0.000
M80.8 Other osteoporosis with pathological fracture
0.671 0.328 0.000
M24.02 Loose body in joint (Upper arm)
0.667 0.332 0.000
M42 Spinal osteochondrosis
0.666 0.333 0.000
M00 Pyogenic arthritis
0.665 0.334 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.665 0.335 0.000
M23.37 Other meniscus derangements-Capsular lig
0.661 0.339 0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)
0.654 0.346 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.652 0.348 0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture
0.651 0.349 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.650 0.350 0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)
0.649 0.351 0.000
M81.09 Postmenopausal osteoporosis (Site unspecified)
0.644 0.356 0.000
M86-M90 Other osteopathies
0.643 0.357 0.000
M43.1 Spondylolisthesis
0.643 0.357 0.000
M82 Osteoporosis in diseases classified elsewhere
0.642 0.358 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.641 0.359 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.640 0.359 0.000
M34.9 Systemic sclerosis, unspecified
0.640 0.360 0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)
0.639 0.360 0.000
M54.1 Radiculopathy
0.637 0.363 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.633 0.367 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.633 0.367 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.633 0.367 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.633 0.367 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.633 0.367 0.000
M23.87 Other internal derangements of knee (Capsular ligament)
0.630 0.370 0.000
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)
0.630 0.370 0.000
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.630 0.370 0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.630 0.370 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.629 0.370 0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)
0.629 0.371 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.629 0.371 0.000
M71 Other bursopathies
0.626 0.374 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.626 0.374 0.000
M80.4 Drug-induced osteoporosis with pathological fracture
0.623 0.377 0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture
0.623 0.377 0.000
M80.2 Osteoporosis of disuse with pathological fracture
0.623 0.377 0.000
M23.80 Other internal derangements of knee (Multiple sites)
0.622 0.378 0.000
M41.8 Other forms of scoliosis
0.622 0.378 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.621 0.379 0.000
M60-M63 Disorders of muscles
0.620 0.379 0.000
M24.21 Disorder of ligament (Shoulder region)
0.617 0.383 0.000
M24.1 Other articular cartilage disorders
0.617 0.383 0.000
M79.1 Myalgia
0.615 0.385 0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)
0.613 0.387 0.000
M25.86 Other specified joint disorders (Lower leg)
0.611 0.389 0.000
M23.47 Loose body in knee-Capsular lig
0.609 0.391 0.000
M23.46 Loose body in knee-O/unsp lat men
0.609 0.391 0.000
M23.45 Loose body in knee-Pst hrn lat men
0.609 0.391 0.000
M23.44 Loose body in knee-Lat lig/ant men
0.609 0.391 0.000
M23.43 Loose body in knee-Med lig/oth men
0.609 0.391 0.000
M23.42 Loose body in knee-Pst lig/hrn men
0.609 0.391 0.000
M23.41 Loose body in knee-Ant lig/hrn men
0.609 0.391 0.000
M23.40 Loose body in knee-Mult sites
0.609 0.391 0.000
M79.7 Fibromyalgia
0.609 0.391 0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)
0.608 0.392 0.000
M33.9 Dermatopolymyositis, unspecified
0.607 0.393 0.000
M33.0 Juvenile dermatomyositis
0.607 0.393 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.607 0.393 0.000
M25.89 Other specified joint disorders (Site unspecified)
0.607 0.393 0.000
M25.88 Other specified joint disorders (Other)
0.607 0.393 0.000
M25.83 Other specified joint disorders (Forearm)
0.607 0.393 0.000
M25.82 Other specified joint disorders (Upper arm)
0.607 0.393 0.000
M25.80 Other specified joint disorders (Multiple sites)
0.607 0.393 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.605 0.395 0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)
0.604 0.395 0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)
0.604 0.395 0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)
0.604 0.395 0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)
0.604 0.395 0.000
M33.1 Other dermatomyositis
0.604 0.395 0.000
M30.8 Other conditions related to polyarteritis nodosa
0.603 0.397 0.000
M30.3 Mucocutaneous lymph node syndrome [Kawasaki]
0.603 0.397 0.000
M30.2 Juvenile polyarteritis
0.603 0.397 0.000
M30.0 Polyarteritis nodosa
0.603 0.397 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.603 0.397 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.602 0.398 0.000
M76 Enthesopathies of lower limb, excluding foot
0.601 0.399 0.000
M23.9 Internal derangement of knee, unspecified
0.600 0.400 0.000
M24.27 Disorder of ligament (Ankle and foot)
0.597 0.402 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.597 0.403 0.000
M24.29 Disorder of ligament (Site unspecified)
0.597 0.403 0.000
M24.28 Disorder of ligament (Other)
0.597 0.403 0.000
M24.25 Disorder of ligament (Pelvic region and thigh)
0.597 0.403 0.000
M24.22 Disorder of ligament (Upper arm)
0.597 0.403 0.000
M24.20 Disorder of ligament (Multiple sites)
0.597 0.403 0.000
M72 Fibroblastic disorders
0.597 0.403 0.000
M41.5 Other secondary scoliosis
0.596 0.404 0.000
M41.4 Neuromuscular scoliosis
0.596 0.404 0.000
M41.3 Thoracogenic scoliosis
0.596 0.404 0.000
M41.2 Other idiopathic scoliosis
0.596 0.404 0.000
M41.1 Juvenile idiopathic scoliosis
0.596 0.404 0.000
M41.0 Infantile idiopathic scoliosis
0.596 0.404 0.000
M34.1 CR(E)ST syndrome
0.594 0.406 0.000
M54.2 Cervicalgia
0.592 0.408 0.000
M80.98 Unspecified osteoporosis with pathological fracture (Other)
0.592 0.408 0.000
M23.03 Cystic meniscus (Medial collateral ligament or Other and unspecified medial meniscus)
0.591 0.409 0.000
M47.16 Other spondylosis with myelopathy (Lumbar region)
0.590 0.410 0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)
0.589 0.410 0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)
0.589 0.410 0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)
0.589 0.410 0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)
0.589 0.410 0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)
0.589 0.410 0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)
0.589 0.410 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.588 0.412 0.000
M79.5 Residual foreign body in soft tissue
0.588 0.412 0.000
M46.4 Discitis, unspecified
0.587 0.413 0.000
M54.16 Radiculopathy (Lumbar region)
0.587 0.413 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.587 0.413 0.000
M31.3 Wegener's granulomatosis
0.584 0.416 0.000
M51.8 Other specified intervertebral disk disorders
0.583 0.417 0.000
M41.90 Scoliosis, unspecified (Multiple sites in spine)
0.583 0.417 0.000
M24.4 Recurrent dislocation and subluxation of joint
0.582 0.418 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.577 0.423 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.577 0.423 0.000
M02 Reactive arthropathies
0.577 0.423 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.577 0.423 0.000
M23.06 Cystic meniscus (Other and unspecified lateral meniscus)
0.577 0.423 0.000
M40.5 Lordosis, unspecified
0.576 0.424 0.000
M41.95 Scoliosis, unspecified (Thoracolumbar region)
0.576 0.424 0.000
M65 Synovitis and tenosynovitis
0.575 0.425 0.000
M84.4 Pathological fracture, not elsewhere classified
0.575 0.425 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.572 0.428 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.572 0.428 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.572 0.428 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.572 0.428 0.000
M34.2 Systemic sclerosis induced by drugs and chemicals
0.570 0.430 0.000
M34.0 Progressive systemic sclerosis
0.570 0.430 0.000
M81.08 Postmenopausal osteoporosis (Other)
0.568 0.432 0.000
M81.07 Postmenopausal osteoporosis (Ankle and foot)
0.568 0.432 0.000
M81.06 Postmenopausal osteoporosis (Lower leg)
0.568 0.432 0.000
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)
0.568 0.432 0.000
M81.04 Postmenopausal osteoporosis (Hand)
0.568 0.432 0.000
M81.03 Postmenopausal osteoporosis (Forearm)
0.568 0.432 0.000
M81.02 Postmenopausal osteoporosis (Upper arm)
0.568 0.432 0.000
M81.01 Postmenopausal osteoporosis (Shoulder region)
0.568 0.432 0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)
0.568 0.432 0.000
M24.51 Contracture of joint (Shoulder region)
0.566 0.434 0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)
0.566 0.434 0.000
M00.9 Pyogenic arthritis, unspecified
0.565 0.435 0.000
M91-M94 Chondropathies
0.565 0.435 0.000
M32.1 Systemic lupus erythematosus with organ or system involvement
0.564 0.436 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.562 0.438 0.000
M80.0 Postmenopausal osteoporosis with pathological fracture
0.559 0.441 0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)
0.557 0.443 0.000
M24.56 Contracture of joint (Lower leg)
0.557 0.443 0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)
0.556 0.444 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.554 0.445 0.000
M34.8 Other forms of systemic sclerosis
0.554 0.445 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.553 0.446 0.000
M21.1 Varus deformity, not elsewhere classified
0.552 0.448 0.000
M24.23 Disorder of ligament (Forearm)
0.552 0.448 0.000
M46.8 Other specified inflammatory spondylopathies
0.552 0.448 0.000
M46.5 Other infective spondylopathies
0.552 0.448 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.552 0.448 0.000
M46.2 Osteomyelitis of vertebra
0.552 0.448 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.552 0.448 0.000
M46.0 Spinal enthesopathy
0.552 0.448 0.000
M41.94 Scoliosis, unspecified (Thoracic region)
0.551 0.448 0.000
M84.9 Disorder of continuity of bone, unspecified
0.551 0.449 0.000
M84.8 Other disorders of continuity of bone
0.551 0.449 0.000
M84.3 Stress fracture, not elsewhere classified
0.551 0.449 0.000
M84.2 Delayed union of fracture
0.551 0.449 0.000
M25.06 Haemarthrosis (Lower leg)
0.551 0.449 0.000
M24.09 Loose body in joint (Site unspecified)
0.549 0.451 0.000
M24.08 Loose body in joint (Other)
0.549 0.451 0.000
M24.06 Loose body in joint-Lower leg
0.549 0.451 0.000
M24.05 Loose body in joint (Pelvic region and thigh)
0.549 0.451 0.000
M24.04 Loose body in joint (Hand)
0.549 0.451 0.000
M24.03 Loose body in joint (Forearm)
0.549 0.451 0.000
M24.01 Loose body in joint (Shoulder region)
0.549 0.451 0.000
M24.00 Loose body in joint (Multiple sites)
0.549 0.451 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.549 0.451 0.000
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)
0.548 0.452 0.000
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)
0.548 0.452 0.000
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)
0.548 0.452 0.000
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)
0.548 0.452 0.000
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)
0.548 0.452 0.000
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)
0.548 0.452 0.000
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)
0.548 0.452 0.000
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)
0.548 0.452 0.000
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)
0.548 0.452 0.000
M23.16 Discoid meniscus (congenital) (Other and unspecified lateral meniscus)
0.547 0.452 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.546 0.454 0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)
0.546 0.454 0.000
M23.09 Cystic meniscus (Unspecified ligament or Unspecified meniscus)
0.546 0.454 0.000
M23.07 Cystic meniscus-Capsular lig
0.546 0.454 0.000
M23.05 Cystic meniscus (Posterior horn of lateral meniscus)
0.546 0.454 0.000
M23.04 Cystic meniscus (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.546 0.454 0.000
M23.02 Cystic meniscus (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.546 0.454 0.000
M23.01 Cystic meniscus (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.546 0.454 0.000
M23.00 Cystic meniscus (Multiple sites)
0.546 0.454 0.000
M24.66 Ankylosis of joint (Lower leg)
0.545 0.455 0.000
M25.81 Other specified joint disorders (Shoulder region)
0.544 0.455 0.000
M54.22 Cervicalgia (Cervical region)
0.543 0.457 0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)
0.543 0.457 0.000
M43.9 Deforming dorsopathy, unspecified
0.543 0.457 0.000
M43.8 Other specified deforming dorsopathies
0.543 0.457 0.000
M43.6 Torticollis
0.543 0.457 0.000
M43.5 Other recurrent vertebral subluxation
0.543 0.457 0.000
M43.4 Other recurrent atlantoaxial subluxation
0.543 0.457 0.000
M43.3 Recurrent atlantoaxial subluxation with myelopathy
0.543 0.457 0.000
M43.2 Other fusion of spine
0.543 0.457 0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)
0.540 0.460 0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)
0.540 0.460 0.000
M41.93 Scoliosis, unspecified (Cervicothoracic region)
0.540 0.460 0.000
M41.92 Scoliosis, unspecified (Cervical region)
0.540 0.460 0.000
M41.91 Scoliosis, unspecified (Occipito-atlanto-axial region)
0.540 0.460 0.000
M54.4 Lumbago with sciatica
0.540 0.460 0.000
M89 Other disorders of bone
0.537 0.463 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.536 0.464 0.000
M43.12 Spondylolisthesis (Cervical region)
0.535 0.465 0.000
M32.9 Systemic lupus erythematosus, unspecified
0.535 0.465 0.000
M32.8 Other forms of systemic lupus erythematosus
0.535 0.465 0.000
M32.0 Drug-induced systemic lupus erythematosus
0.535 0.465 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.534 0.466 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.534 0.466 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.534 0.466 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.534 0.466 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.534 0.466 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.534 0.466 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.534 0.466 0.000
M25.31 Other instability of joint (Shoulder region)
0.534 0.466 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.534 0.466 0.000
M49.8 Spondylopathy in other diseases classified elsewhere
0.532 0.467 0.000
M49.4 Neuropathic spondylopathy
0.532 0.467 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.532 0.467 0.000
M49.2 Enterobacterial spondylitis
0.532 0.467 0.000
M49.1 Brucella spondylitis
0.532 0.467 0.000
M49.0 Tuberculosis of spine
0.532 0.467 0.000
M25.54 Pain in joint (Hand)
0.530 0.470 0.000
M80.88 Other osteoporosis with pathological fracture (Other)
0.530 0.470 0.000
M25.09 Haemarthrosis (Site unspecified)
0.528 0.471 0.000
M25.08 Haemarthrosis (Other)
0.528 0.471 0.000
M25.07 Haemarthrosis (Ankle and foot)
0.528 0.471 0.000
M25.05 Haemarthrosis (Pelvic region and thigh)
0.528 0.471 0.000
M25.04 Haemarthrosis (Hand)
0.528 0.471 0.000
M25.03 Haemarthrosis (Forearm)
0.528 0.471 0.000
M25.02 Haemarthrosis (Upper arm)
0.528 0.471 0.000
M25.01 Haemarthrosis (Shoulder region)
0.528 0.471 0.000
M25.00 Haemarthrosis (Multiple sites)
0.528 0.471 0.000
M25.50 Pain in joint (Multiple sites)
0.524 0.476 0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)
0.524 0.476 0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)
0.524 0.476 0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)
0.524 0.476 0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)
0.524 0.476 0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)
0.524 0.476 0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)
0.524 0.476 0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)
0.524 0.476 0.000
M43.0 Spondylolysis
0.524 0.476 0.000
M71.3 Other bursal cyst
0.523 0.477 0.000
M25.53 Pain in joint (Forearm)
0.522 0.478 0.000
M25.34 Other instability of joint (Hand)
0.521 0.479 0.000
M79.19 Myalgia (Site unspecified)
0.521 0.479 0.000
M24.59 Contracture of joint (Site unspecified)
0.521 0.479 0.000
M24.58 Contracture of joint (Other)
0.521 0.479 0.000
M24.57 Contracture of joint (Ankle and foot)
0.521 0.479 0.000
M24.55 Contracture of joint (Pelvic region and thigh)
0.521 0.479 0.000
M24.53 Contracture of joint (Forearm)
0.521 0.479 0.000
M24.52 Contracture of joint (Upper arm)
0.521 0.479 0.000
M24.50 Contracture of joint (Multiple sites)
0.521 0.479 0.000
M43.17 Spondylolisthesis (Lumbosacral region)
0.520 0.480 0.000
M40.4 Other lordosis
0.519 0.481 0.000
M40.3 Flatback syndrome
0.519 0.481 0.000
M40.2 Other and unspecified kyphosis
0.519 0.481 0.000
M40.1 Other secondary kyphosis
0.519 0.481 0.000
M40.0 Postural kyphosis
0.519 0.481 0.000
M23.19 Discoid meniscus (congenital) (Unspecified ligament or Unspecified meniscus)
0.517 0.483 0.000
M23.17 Discoid meniscus (congenital)-Capsular lig
0.517 0.483 0.000
M23.15 Discoid meniscus (congenital) (Posterior horn of lateral meniscus)
0.517 0.483 0.000
M23.14 Discoid meniscus (congenital) (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.517 0.483 0.000
M23.13 Discoid meniscus (congenital) (Medial collateral ligament or Other and unspecified medial meniscus)
0.517 0.483 0.000
M23.12 Discoid meniscus (congenital) (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.517 0.483 0.000
M23.11 Discoid meniscus (congenital) (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.517 0.483 0.000
M23.10 Discoid meniscus (congenital) (Multiple sites)
0.517 0.483 0.000
M23.5 Chronic instability of knee
0.517 0.483 0.001
M47.8 Other spondylosis
0.515 0.485 0.000
M79.9 Soft tissue disorder, unspecified
0.514 0.486 0.000
M79.3 Panniculitis, unspecified
0.514 0.486 0.000
M36.8 Systemic disorders of connective tissue in other diseases classified elsewhere
0.514 0.486 0.000
M36.4 Arthropathy in hypersensitivity reactions classified elsewhere
0.514 0.486 0.000
M36.3 Arthropathy in other blood disorders
0.514 0.486 0.000
M36.2 Haemophilic arthropathy
0.514 0.486 0.000
M36.1 Arthropathy in neoplastic disease
0.514 0.486 0.000
M36.0 Dermato(poly)myositis in neoplastic disease
0.514 0.486 0.000
M83.9 Adult osteomalacia, unspecified
0.514 0.486 0.000
M83.8 Other adult osteomalacia
0.514 0.486 0.000
M83.5 Other drug-induced osteomalacia in adults
0.514 0.486 0.000
M83.4 Aluminum bone disease
0.514 0.486 0.000
M83.3 Adult osteomalacia due to malnutrition
0.514 0.486 0.000
M83.2 Adult osteomalacia due to malabsorption
0.514 0.486 0.000
M83.1 Senile osteomalacia
0.514 0.486 0.000
M83.0 Puerperal osteomalacia
0.514 0.486 0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)
0.513 0.486 0.000
M81.18 Postoophorectomy osteoporosis (Other)
0.513 0.486 0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)
0.513 0.486 0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)
0.513 0.486 0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)
0.513 0.486 0.000
M81.14 Postoophorectomy osteoporosis (Hand)
0.513 0.486 0.000
M81.13 Postoophorectomy osteoporosis (Forearm)
0.513 0.486 0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)
0.513 0.486 0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)
0.513 0.486 0.000
M81.10 Postoophorectomy osteoporosis (Multiple sites)
0.513 0.486 0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)
0.513 0.486 0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)
0.513 0.486 0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)
0.513 0.486 0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)
0.513 0.486 0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)
0.513 0.486 0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)
0.513 0.486 0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)
0.513 0.486 0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)
0.513 0.486 0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)
0.513 0.486 0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)
0.513 0.486 0.000
M81.59 Idiopathic osteoporosis (Site unspecified)
0.513 0.486 0.000
M81.58 Idiopathic osteoporosis (Other)
0.513 0.486 0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)
0.513 0.486 0.000
M81.56 Idiopathic osteoporosis (Lower leg)
0.513 0.486 0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)
0.513 0.486 0.000
M81.54 Idiopathic osteoporosis (Hand)
0.513 0.486 0.000
M81.53 Idiopathic osteoporosis (Forearm)
0.513 0.486 0.000
M81.52 Idiopathic osteoporosis (Upper arm)
0.513 0.486 0.000
M81.51 Idiopathic osteoporosis (Shoulder region)
0.513 0.486 0.000
M81.50 Idiopathic osteoporosis (Multiple sites)
0.513 0.486 0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)
0.513 0.486 0.000
M81.68 Localized osteoporosis [Lequesne] (Other)
0.513 0.486 0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)
0.513 0.486 0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)
0.513 0.486 0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)
0.513 0.486 0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)
0.513 0.486 0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)
0.513 0.486 0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)
0.513 0.486 0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)
0.513 0.486 0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)
0.513 0.486 0.000
M81.89 Other osteoporosis (Site unspecified)
0.513 0.486 0.000
M81.88 Other osteoporosis (Other)
0.513 0.486 0.000
M81.87 Other osteoporosis (Ankle and foot)
0.513 0.486 0.000
M81.86 Other osteoporosis (Lower leg)
0.513 0.486 0.000
M81.85 Other osteoporosis (Pelvic region and thigh)
0.513 0.486 0.000
M81.84 Other osteoporosis (Hand)
0.513 0.486 0.000
M81.83 Other osteoporosis (Forearm)
0.513 0.486 0.000
M81.82 Other osteoporosis (Upper arm)
0.513 0.486 0.000
M81.81 Other osteoporosis (Shoulder region)
0.513 0.486 0.000
M81.80 Other osteoporosis (Multiple sites)
0.513 0.486 0.000
M25.36 Other instability of joint (Lower leg)
0.513 0.487 0.000
M25.19 Fistula of joint (Site unspecified)
0.512 0.487 0.000
M25.18 Fistula of joint (Other)
0.512 0.487 0.000
M25.17 Fistula of joint (Ankle and foot)
0.512 0.487 0.000
M25.16 Fistula of joint (Lower leg)
0.512 0.487 0.000
M25.15 Fistula of joint (Pelvic region and thigh)
0.512 0.487 0.000
M25.14 Fistula of joint (Hand)
0.512 0.487 0.000
M25.13 Fistula of joint (Forearm)
0.512 0.487 0.000
M25.12 Fistula of joint (Upper arm)
0.512 0.487 0.000
M25.11 Fistula of joint (Shoulder region)
0.512 0.487 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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