TreeWAS – Variant ID: rs1192201

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.485	0.515	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.483	0.517	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.483	0.517	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.423	0.577	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.394	0.606	0.000
T82.3 Mechanical complication of other vascular grafts	0.381	0.619	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.354	0.646	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.346	0.654	0.000
T82.1 Mechanical complication of cardiac electronic device	0.338	0.662	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.319	0.681	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.295	0.705	0.000
T85 Complications of other internal prosthetic devices, implants and grafts	0.163	0.837	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.161	0.839	0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.151	0.849	0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft	0.143	0.857	0.000
T85.4 Mechanical complication of breast prosthesis and implant	0.142	0.858	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.139	0.861	0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system	0.135	0.865	0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.127	0.873	0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts	0.127	0.873	0.000
T86 Failure and rejection of transplanted organs and tissues	0.126	0.874	0.000
T87 Complications peculiar to reattachment and amputation	0.123	0.877	0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt	0.116	0.884	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.114	0.886	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.109	0.891	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.100	0.900	0.000
T87.6 Other and unspecified complications of amputation stump	0.099	0.900	0.000
T86.1 Kidney transplant failure and rejection	0.097	0.903	0.000
T87.3 Neuroma of amputation stump	0.093	0.907	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.091	0.908	0.000
T86.3 Heart-lung transplant failure and rejection	0.091	0.909	0.000
T86.2 Heart transplant failure and rejection	0.091	0.909	0.000
T86.4 Liver transplant failure and rejection	0.088	0.911	0.000
T87.2 Complications of other reattached body part	0.088	0.912	0.000
T87.1 Complications of reattached (part of) lower extremity	0.088	0.912	0.000
T87.0 Complications of reattached (part of) upper extremity	0.088	0.912	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.087	0.913	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.085	0.914	0.000
T87.5 Necrosis of amputation stump	0.084	0.916	0.000
T87.4 Infection of amputation stump	0.081	0.918	0.000
T85.2 Mechanical complication of intraocular lens	0.073	0.926	0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.073	0.927	0.000
T83.2 Mechanical complication of graft of urinary organ	0.069	0.931	0.000
T86.0 Bone-marrow transplant rejection	0.068	0.931	0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.068	0.932	0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.067	0.933	0.000
T83.0 Mechanical complication of urinary (indwelling) catheter	0.063	0.937	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.058	0.941	0.001
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.056	0.944	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.052	0.947	0.000
T83.3 Mechanical complication of intra-uterine contraceptive device	0.050	0.949	0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.047	0.953	0.000
T84.3 Mechanical complication of other bone devices, implants and grafts	0.045	0.955	0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.044	0.956	0.000
T80.6 Other serum reactions	0.042	0.958	0.001
T80.5 Anaphylactic shock due to serum	0.042	0.958	0.001
T80.4 Rh incompatibility reaction	0.042	0.958	0.001
T80.3 ABO incompatibility reaction	0.042	0.958	0.001
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.042	0.958	0.001
T88 Other complications of surgical and medical care, not elsewhere classified	0.041	0.959	0.001
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.041	0.959	0.000
T84.2 Mechanical complication of internal fixation device of other bones	0.041	0.959	0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.039	0.961	0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.038	0.962	0.001
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.036	0.964	0.000
R39.1 Other difficulties with micturition	0.035	0.965	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.035	0.965	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.034	0.965	0.001
T80.9 Unspecified complication following infusion, transfusion and therapeutic injection	0.033	0.966	0.001
T80.2 Infections following infusion, transfusion and therapeutic injection	0.032	0.968	0.001
T88.5 Other complications of anaesthesia	0.032	0.968	0.000
T88.2 Shock due to anaesthesia	0.031	0.969	0.001
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.030	0.969	0.000
R39 Other symptoms and signs involving the urinary system	0.030	0.970	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.030	0.970	0.000
T88.1 Other complications following immunisation, not elsewhere classified	0.029	0.970	0.001
T88.0 Infection following immunisation	0.029	0.970	0.001
T88.3 Malignant hyperthermia due to anaesthesis	0.029	0.970	0.001
T88.9 Complication of surgical and medical care, unspecified	0.024	0.975	0.001
R39.0 Extravasation of urine	0.022	0.977	0.000
R39.2 Extrarenal uraemia	0.022	0.978	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.020	0.979	0.001
T88.7 Unspecified adverse effect of drug or medicament	0.018	0.981	0.001
T84.0 Mechanical complication of internal joint prosthesis	0.017	0.983	0.000
T88.4 Failed or difficult intubation	0.016	0.983	0.001
N13.3 Other and unspecified hydronephrosis	0.015	0.985	0.000
T81 Complications of procedures, not elsewhere classified	0.009	0.991	0.000
T84.1 Mechanical complication of internal fixation device of bones of limb	0.006	0.993	0.001
Z09.2 Follow-up examination after chemotherapy for other conditions	0.007	0.993	0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.007	0.993	0.000
N13 Obstructive and reflux uropathy	0.007	0.993	0.000
T81.7 Vascular complications following a procedure, not elsewhere classified	0.007	0.993	0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.006	0.993	0.000
R35 Polyuria	0.006	0.994	0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess	0.006	0.994	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.006	0.994	0.000
T81.9 Unspecified complication of procedure	0.006	0.994	0.000
R30-R39 Symptoms and signs involving the urinary system	0.006	0.994	0.000
Z09.0 Follow-up examination after surgery for other conditions	0.006	0.994	0.000
N13.4 Hydroureter	0.006	0.994	0.000
N13.7 Vesicoureteral-reflux-associated uropathy	0.006	0.994	0.000
T81.8 Other complications of procedures, not elsewhere classified	0.006	0.994	0.000
N13.8 Other obstructive and reflux uropathy	0.005	0.994	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.005	0.994	0.000
R30 Pain associated with micturition	0.005	0.995	0.000
M10.97 Gout, unspecified (Ankle and foot)	0.005	0.995	0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.005	0.995	0.000
R30.0 Dysuria	0.005	0.995	0.000
D35.1 Parathyroid gland	0.000	0.995	0.005
N13.6 Pyonephrosis	0.005	0.995	0.000
S22.30 Fracture of rib (closed)	0.005	0.995	0.000
C25.9 Pancreas, unspecified	0.005	0.995	0.000
N13.9 Obstructive and reflux uropathy, unspecified	0.004	0.996	0.000
R36 Urethral discharge	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
S22.3 Fracture of rib	0.004	0.996	0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.004	0.996	0.000
C25.0 Head of pancreas	0.004	0.996	0.000
R34 Anuria and oliguria	0.004	0.996	0.000
R30.9 Painful micturition, unspecified	0.004	0.996	0.000
R30.1 Vesical tenesmus	0.004	0.996	0.000
D35.0 Adrenal gland	0.000	0.996	0.004
K56.6 Other and unspecified intestinal obstruction	0.004	0.996	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.996	0.004
S22 Fracture of rib(s), sternum and thoracic spine	0.004	0.996	0.000
C25.1 Body of pancreas	0.004	0.996	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.004	0.996	0.000
C25.3 Pancreatic duct	0.004	0.996	0.000
D35.2 Pituitary gland	0.000	0.996	0.004
N13.5 Kinking and stricture of ureter without hydronephrosis	0.004	0.996	0.000
C25.7 Other parts of pancreas	0.004	0.996	0.000
S22.4 Multiple fractures of ribs	0.004	0.996	0.000
M10.9 Gout, unspecified	0.003	0.996	0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.003	0.996	0.000
C25.4 Endocrine pancreas	0.003	0.997	0.000
C25.2 Tail of pancreas	0.003	0.997	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.997	0.000
S20-S29 Injuries to the thorax	0.003	0.997	0.000
M10.99 Gout, unspecified (Site unspecified)	0.003	0.997	0.000
S22.40 Multiple fractures of ribs (closed)	0.003	0.997	0.000
Z09.1 Follow-up examination after radiotherapy for other conditions	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.003	0.997	0.000
K92.1 Melaena	0.003	0.997	0.000
S22.5 Flail chest	0.003	0.997	0.000
Z09.3 Follow-up examination after psychotherapy	0.003	0.997	0.000
K92.0 Haematemesis	0.003	0.997	0.000
Z09.4 Follow-up examination after treatment of fracture	0.003	0.997	0.000
G51.0 Bell's palsy	0.003	0.997	0.000
S22.1 Multiple fractures of thoracic spine	0.003	0.997	0.000
D35.9 Endocrine gland, unspecified	0.000	0.997	0.003
D35.8 Pluriglandular involvement	0.000	0.997	0.003
D35.7 Other specified endocrine glands	0.000	0.997	0.003
D35.6 Aortic body and other paraganglia	0.000	0.997	0.003
D35.5 Carotid body	0.000	0.997	0.003
D35.4 Pineal gland	0.000	0.997	0.003
D35.3 Craniopharyngeal duct	0.000	0.997	0.003
S22.9 Fracture of bony thorax, part unspecified	0.003	0.997	0.000
S22.8 Fracture of other parts of bony thorax	0.003	0.997	0.000
T81.4 Infection following a procedure, not elsewhere classified	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.003	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.003	0.997	0.000
M10.93 Gout, unspecified (Forearm)	0.003	0.997	0.000
I49.1 Atrial premature depolarisation	0.003	0.997	0.000
S22.2 Fracture of sternum	0.003	0.997	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.003	0.997	0.000
I49.0 Ventricular fibrillation and flutter	0.003	0.997	0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions	0.003	0.997	0.000
S20 Superficial injury of thorax	0.003	0.997	0.000
S22.41 Multiple fractures of ribs (open)	0.003	0.997	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.003	0.997	0.000
E04.1 Non-toxic single thyroid nodule	0.003	0.997	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.003	0.997	0.000
S29 Other and unspecified injuries of thorax	0.003	0.997	0.000
S22.50 Flail chest (closed)	0.003	0.997	0.000
M10.98 Gout, unspecified (Other)	0.003	0.997	0.000
M10.95 Gout, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M10.91 Gout, unspecified (Shoulder region)	0.003	0.997	0.000
S27.3 Other injuries of lung	0.003	0.997	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.003	0.997	0.000
S24 Injury of nerves and spinal cord at thorax level	0.003	0.997	0.000
B18.2 Chronic viral hepatitis C	0.003	0.997	0.000
M10.94 Gout, unspecified (Hand)	0.003	0.997	0.000
S27.2 Traumatic heamopneumothorax	0.003	0.997	0.000
I49 Other cardiac arrhythmias	0.003	0.997	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.003	0.997	0.000
S25 Injury of blood vessels of thorax	0.003	0.997	0.000
S21 Open wound of thorax	0.003	0.997	0.000
I49.3 Ventricular premature depolarisation	0.003	0.997	0.000
M10.0 Idiopathic gout	0.003	0.997	0.000
Z11.0 Special screening examination for intestinal infectious diseases	0.003	0.997	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.003	0.997	0.000
S26 Injury of heart	0.003	0.997	0.000
S22.51 Flail chest (open)	0.002	0.997	0.000
K57 Diverticular disease of intestine	0.003	0.997	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.002	0.997	0.000
T42.4 Benzodiazepines	0.003	0.997	0.000
M10.07 Idiopathic gout (Ankle and foot)	0.002	0.997	0.000
M10.92 Gout, unspecified (Upper arm)	0.002	0.997	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.997	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.002	0.997	0.000
H01.0 Blepharitis	0.000	0.997	0.003
M10.90 Gout, unspecified (Multiple sites)	0.002	0.997	0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.003	0.997	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.002	0.997	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.002	0.997	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.002	0.997	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.002	0.997	0.000
R31 Unspecified haematuria	0.003	0.997	0.000
S23.4 Sprain and strain of ribs and sternum	0.002	0.998	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.002	0.998	0.000
S27.1 Traumatic haemothorax	0.002	0.998	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.002	0.998	0.000
S22.01 Fracture of thoracic vertebra (open)	0.002	0.998	0.000
S27.9 Injury of unspecified intrathoracic organ	0.002	0.998	0.000
S27.7 Multiple injuries of intrathoracic organs	0.002	0.998	0.000
S27.6 Injury of pleura	0.002	0.998	0.000
S27.5 Injury of thoracic trachea	0.002	0.998	0.000
S27.4 Injury of bronchus	0.002	0.998	0.000
S29.9 Unspecified injury of thorax	0.002	0.998	0.000
M10 Gout	0.002	0.998	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
S20.0 Contusion of breast	0.002	0.998	0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess	0.002	0.998	0.000
K92 Other diseases of digestive system	0.002	0.998	0.000
S20.4 Other superficial injuries of back wall of thorax	0.002	0.998	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
S22.21 Fracture of sternum (open)	0.002	0.998	0.000
M10.06 Idiopathic gout (Lower leg)	0.002	0.998	0.000
S20.7 Multiple superficial injuries of thorax	0.002	0.998	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.002	0.998	0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess	0.002	0.998	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.002	0.998	0.000
S23.3 Sprain and strain of thoracic spine	0.002	0.998	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.002	0.998	0.000
S23.1 Dislocation of thoracic vertebra	0.002	0.998	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.002	0.998	0.000
S27.8 Injury of other specified intrathoracic organs	0.002	0.998	0.000
S29.0 Injury of muscle and tendon at thorax level	0.002	0.998	0.000
M10.09 Idiopathic gout (Site unspecified)	0.002	0.998	0.000
M10.00 Idiopathic gout (Multiple sites)	0.002	0.998	0.000
S29.7 Multiple injuries of thorax	0.002	0.998	0.000
M10.02 Idiopathic gout (Upper arm)	0.002	0.998	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
S20.1 Other and unspecified superficial injuries of breast	0.002	0.998	0.000
S21.9 Open wound of thorax, part unspecified	0.002	0.998	0.000
S21.0 Open wound of breast	0.002	0.998	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.002	0.998	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.002	0.998	0.000
S24.6 Injury of unspecified nerve of thorax	0.002	0.998	0.000
S24.5 Injury of other nerves of thorax	0.002	0.998	0.000
S24.4 Injury of thoracic sympathetic nerves	0.002	0.998	0.000
S24.3 Injury of peripheral nerves of thorax	0.002	0.998	0.000
S24.2 Injury of nerve root of thoracic spine	0.002	0.998	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.002	0.998	0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history	0.002	0.998	0.000
T42.1 Iminostilbenes	0.002	0.998	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
C15.9 Oesophagus, unspecified	0.000	0.998	0.002
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.002	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
M10.04 Idiopathic gout (Hand)	0.002	0.998	0.000
I49.8 Other specified cardiac arrhythmias	0.002	0.998	0.000
I49.2 Junctional premature depolarisation	0.002	0.998	0.000
S21.8 Open wound of other parts of thorax	0.002	0.998	0.000
S21.7 Multiple open wounds of thoracic wall	0.002	0.998	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.002	0.998	0.000
S25.8 Injury of other blood vessels of thorax	0.002	0.998	0.000
S25.7 Injury of multiple blood vessels of thorax	0.002	0.998	0.000
S25.5 Injury of intercostal blood vessels	0.002	0.998	0.000
S25.4 Injury of pulmonary blood vessels	0.002	0.998	0.000
S25.3 Injury of innominate or subclavian vein	0.002	0.998	0.000
S25.2 Injury of superior vena cava	0.002	0.998	0.000
S25.1 Injury of innominate or subclavian artery	0.002	0.998	0.000
S25.0 Injury of thoracic aorta	0.002	0.998	0.000
S28.1 Traumatic amputation of part of thorax	0.002	0.998	0.000
S28.0 Crushed chest	0.002	0.998	0.000
S29.8 Other specified injuries of thorax	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.002	0.998	0.000
S50.0 Contusion of elbow	0.002	0.998	0.000
S50 Superficial injury of forearm	0.002	0.998	0.000
M10.08 Idiopathic gout (Other)	0.002	0.998	0.000
M10.05 Idiopathic gout (Pelvic region and thigh)	0.002	0.998	0.000
M10.03 Idiopathic gout (Forearm)	0.002	0.998	0.000
M10.01 Idiopathic gout (Shoulder region)	0.002	0.998	0.000
H90.2 Conductive hearing loss, unspecified	0.002	0.998	0.000
S26.9 Injury of heart, unspecified	0.002	0.998	0.000
S26.0 Injury of heart with haemopericardium	0.002	0.998	0.000
S27.0 Traumatic pneumothorax	0.002	0.998	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.002	0.998	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.002	0.998	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.002	0.998	0.000
I49.9 Cardiac arrhythmia, unspecified	0.002	0.998	0.000
K92.8 Other specified diseases of digestive system	0.002	0.998	0.000
S26.8 Other injuries of heart	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
I49.4 Other and unspecified premature depolarisation	0.002	0.998	0.000
S50.9 Superficial injury of forearm, unspecified	0.002	0.998	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
S22.20 Fracture of sternum (closed)	0.002	0.998	0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess	0.002	0.998	0.000
S20.3 Other superficial injuries of front wall of thorax	0.002	0.998	0.000
S21.1 Open wound of front wall of thorax	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.002	0.998	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.002	0.998	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.002	0.998	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.998	0.000
T42.3 Barbiturates	0.002	0.998	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.002	0.998	0.000
S82.10 Fracture of upper end of tibia (closed)	0.002	0.998	0.000
H25.8 Other senile cataract	0.002	0.998	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.002	0.998	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.002	0.998	0.000
T42.2 Succinimides and oxazolidinediones	0.002	0.998	0.000
T36 Poisoning by systemic antibiotics	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.002	0.998	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.002	0.998	0.000
K57.2 Diverticular disease of large intestine with perforation and abscess	0.002	0.998	0.000
M10.4 Other secondary gout	0.002	0.998	0.000
M10.2 Drug-induced gout	0.002	0.998	0.000
M10.1 Lead-induced gout	0.002	0.998	0.000
T43.9 Psychotropic drug, unspecified	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.002	0.998	0.000
E04.9 Non-toxic goitre, unspecified	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
S50.8 Other superficial injuries of forearm	0.002	0.998	0.000
M10.3 Gout due to impairment of renal function	0.002	0.998	0.000
T38.9 Other and unspecified hormone antagonists	0.002	0.998	0.000
T38.7 Androgens and anabolic congeners	0.002	0.998	0.000
T38.4 Oral contraceptives	0.002	0.998	0.000
T38.2 Antithyroid drugs	0.002	0.998	0.000
T38.0 Glucocorticoids and synthetic analogues	0.002	0.998	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.002	0.998	0.000
T38.5 Other oestrogens and progestogens	0.002	0.998	0.000
E04 Other non-toxic goitre	0.002	0.998	0.000
S56 Injury of muscle and tendon at forearm level	0.002	0.998	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.002	0.998	0.000
T42.0 Hydantoin derivatives	0.002	0.998	0.000
T43.6 Psychostimulants with abuse potential	0.002	0.998	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.002	0.998	0.000
M10.96 Gout, unspecified (Lower leg)	0.002	0.998	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.002	0.998	0.000
T40.6 Other and unspecified narcotics	0.002	0.998	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.002	0.998	0.000
S20.2 Contusion of thorax	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
T47.4 Other laxatives	0.002	0.998	0.000
T40.1 Heroin	0.002	0.998	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.002	0.998	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.002	0.998	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.002	0.998	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.002	0.998	0.000
T44.0 Anticholinesterase agents	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.002	0.998	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.002	0.998	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.002	0.998	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.002	0.998	0.000
T47.0 Histamine H(2)-receptor antagonists	0.002	0.998	0.000
W08.0 Home	0.000	0.998	0.002
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.002	0.998	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.002	0.998	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.002	0.998	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.002	0.998	0.000
T47.6 Antidiarrhoeal drugs	0.002	0.998	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.002	0.998	0.000
S50.7 Multiple superficial injuries of forearm	0.002	0.998	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.002	0.998	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.002	0.998	0.000
T47.7 Emetics	0.002	0.998	0.000
T47.5 Digestants	0.002	0.998	0.000
T47.3 Saline and osmotic laxatives	0.002	0.998	0.000
C65 Malignant neoplasm of renal pelvis	0.000	0.998	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.998	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.001	0.998	0.000
T41.2 Other and unspecified general anaesthetics	0.002	0.998	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.001	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.002	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.002	0.998	0.000
T40.8 Lysergide [LSD]	0.002	0.998	0.000
T40.7 Cannabis (derivatives)	0.002	0.998	0.000
T40.0 Opium	0.002	0.998	0.000
T47.2 Stimulant laxatives	0.002	0.998	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.002	0.998	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.002	0.998	0.000
W19.4 Street and highway	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
M20.1 Hallux valgus (acquired)	0.002	0.998	0.000
T41.5 Therapeutic gases	0.002	0.998	0.000
T41.4 Anaesthetic, unspecified	0.002	0.998	0.000
T41.3 Local anaesthetics	0.002	0.998	0.000
T41.1 Intravenous anaesthetics	0.002	0.998	0.000
T41.0 Inhaled anaesthetics	0.002	0.998	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.002	0.998	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.001	0.998	0.000
T36.4 Tetracyclines	0.002	0.998	0.000
T40.3 Methadone	0.002	0.998	0.000
T49.9 Topical agent, unspecified	0.002	0.998	0.000
T49.8 Other topical agents	0.002	0.998	0.000
T49.7 Dental drugs, topically applied	0.002	0.998	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.002	0.998	0.000
T49.5 Ophthalmological drugs and preparations	0.002	0.998	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.002	0.998	0.000
T49.3 Emollients, demulcents and protectants	0.002	0.998	0.000
T49.2 Local astringents and local detergents	0.002	0.998	0.000
T49.1 Antipruritics	0.002	0.998	0.000
S50-S59 Injuries to the elbow and forearm	0.002	0.998	0.000
M10.19 Lead-induced gout (Site unspecified)	0.001	0.998	0.000
M10.18 Lead-induced gout (Other)	0.001	0.998	0.000
M10.17 Lead-induced gout (Ankle and foot)	0.001	0.998	0.000
M10.16 Lead-induced gout (Lower leg)	0.001	0.998	0.000
M10.15 Lead-induced gout (Pelvic region and thigh)	0.001	0.998	0.000
M10.14 Lead-induced gout (Hand)	0.001	0.998	0.000
M10.13 Lead-induced gout (Forearm)	0.001	0.998	0.000
M10.12 Lead-induced gout (Upper arm)	0.001	0.998	0.000
M10.11 Lead-induced gout (Shoulder region)	0.001	0.998	0.000
M10.10 Lead-induced gout (Multiple sites)	0.001	0.998	0.000
M10.29 Drug-induced gout (Site unspecified)	0.001	0.998	0.000
M10.28 Drug-induced gout (Other)	0.001	0.998	0.000
M10.27 Drug-induced gout (Ankle and foot)	0.001	0.998	0.000
M10.26 Drug-induced gout (Lower leg)	0.001	0.998	0.000
M10.25 Drug-induced gout (Pelvic region and thigh)	0.001	0.998	0.000
M10.24 Drug-induced gout (Hand)	0.001	0.998	0.000
M10.23 Drug-induced gout (Forearm)	0.001	0.998	0.000
M10.22 Drug-induced gout (Upper arm)	0.001	0.998	0.000
M10.21 Drug-induced gout (Shoulder region)	0.001	0.998	0.000
M10.20 Drug-induced gout (Multiple sites)	0.001	0.998	0.000
M10.49 Other secondary gout (Site unspecified)	0.001	0.998	0.000
M10.48 Other secondary gout (Other)	0.001	0.998	0.000
M10.47 Other secondary gout (Ankle and foot)	0.001	0.998	0.000
M10.46 Other secondary gout (Lower leg)	0.001	0.998	0.000
M10.45 Other secondary gout (Pelvic region and thigh)	0.001	0.998	0.000
M10.44 Other secondary gout (Hand)	0.001	0.998	0.000
M10.43 Other secondary gout (Forearm)	0.001	0.998	0.000
M10.42 Other secondary gout (Upper arm)	0.001	0.998	0.000
M10.41 Other secondary gout (Shoulder region)	0.001	0.998	0.000
M10.40 Other secondary gout (Multiple sites)	0.001	0.998	0.000
T36.9 Systemic antibiotic, unspecified	0.002	0.998	0.000
T36.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
T36.6 Rifamycins	0.002	0.998	0.000
T36.5 Aminoglycosides	0.002	0.998	0.000
T36.2 Chloramphenicol group	0.002	0.998	0.000
T36.0 Penicillins	0.002	0.998	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Z22.3 Carrier of other specified bacterial diseases	0.002	0.998	0.000
F99 Mental disorder, not otherwise specified	0.000	0.998	0.002
M45.X9 Ankylosing spondylitis (Site unspecified)	0.002	0.998	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.002	0.998	0.000
Y83.2 Surgical operation with anastomosis, bypass or graft	0.002	0.998	0.000
M10.38 Gout due to impairment of renal function (Other)	0.001	0.998	0.000
M10.37 Gout due to impairment of renal function (Ankle and foot)	0.001	0.998	0.000
M10.36 Gout due to impairment of renal function (Lower leg)	0.001	0.998	0.000
M10.35 Gout due to impairment of renal function (Pelvic region and thigh)	0.001	0.998	0.000
M10.34 Gout due to impairment of renal function (Hand)	0.001	0.998	0.000
M10.33 Gout due to impairment of renal function (Forearm)	0.001	0.998	0.000
M10.32 Gout due to impairment of renal function (Upper arm)	0.001	0.998	0.000
M10.31 Gout due to impairment of renal function (Shoulder region)	0.001	0.998	0.000
M10.30 Gout due to impairment of renal function (Multiple sites)	0.001	0.998	0.000
K57.3 Diverticular disease of large intestine without perforation or abscess	0.002	0.998	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.002	0.998	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.002	0.998	0.000
T36.3 Macrolides	0.001	0.998	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.001	0.998	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.001	0.998	0.000
T48.4 Expectorants	0.001	0.998	0.000
T48.3 Antitussives	0.001	0.998	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.001	0.998	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.001	0.998	0.000
T48.0 Oxytocic drugs	0.001	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
E04.8 Other specified non-toxic goitre	0.002	0.998	0.000
T36.8 Other systemic antibiotics	0.001	0.998	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.001	0.998	0.000
T37.5 Antiviral drugs	0.001	0.998	0.000
T37.4 Anthelminthics	0.001	0.998	0.000
T37.3 Other antiprotozoal drugs	0.001	0.998	0.000
T37.1 Antimycobacterial drugs	0.001	0.998	0.000
T37.0 Sulphonamides	0.001	0.998	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.002	0.998	0.000
E24.9 Cushing's syndrome, unspecified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations