TreeWAS – Variant ID: rs11987758

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C44.2 Skin of ear and external auricular canal	0.083	0.917	0.000
C44.7 Skin of lower limb, including hip	0.080	0.920	0.000
C44 Other malignant neoplasms of skin	0.079	0.921	0.000
C44.6 Skin of upper limb, including shoulder	0.077	0.923	0.000
C44.0 Skin of lip	0.069	0.931	0.000
H72 Perforation of tympanic membrane	0.062	0.938	0.000
C44.5 Skin of trunk	0.059	0.941	0.000
H65-H75 Diseases of middle ear and mastoid	0.058	0.942	0.000
H71 Cholesteatoma of middle ear	0.058	0.942	0.000
C44.8 Overlapping lesion of skin	0.057	0.943	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.057	0.943	0.000
H72.0 Central perforation of tympanic membrane	0.056	0.944	0.000
H72.8 Other perforations of tympanic membrane	0.056	0.944	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.055	0.945	0.000
H66 Suppurative and unspecified otitis media	0.051	0.949	0.000
H72.2 Other marginal perforations of tympanic membrane	0.048	0.952	0.000
H72.1 Attic perforation of tympanic membrane	0.047	0.952	0.000
H66.3 Other chronic suppurative otitis media	0.045	0.955	0.000
H70 Mastoiditis and related conditions	0.043	0.957	0.000
H73 Other disorders of tympanic membrane	0.043	0.957	0.000
H74 Other disorders of middle ear and mastoid	0.042	0.957	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.042	0.958	0.000
H68 Eustachian salpingitis and obstruction	0.042	0.958	0.000
H67 Otitis media in diseases classified elsewhere	0.042	0.958	0.000
H66.0 Acute suppurative otitis media	0.038	0.961	0.000
Chapter VIII Diseases of the ear and mastoid process	0.038	0.962	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.038	0.962	0.000
H66.4 Suppurative otitis media, unspecified	0.036	0.963	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.036	0.963	0.000
H90-H95 Other disorders of ear	0.035	0.965	0.000
H69 Other disorders of Eustachian tube	0.034	0.966	0.000
H90 Conductive and sensorineural hearing loss	0.033	0.967	0.000
H74.1 Adhesive middle ear disease	0.033	0.967	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.032	0.967	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.032	0.968	0.000
H66.9 Otitis media, unspecified	0.032	0.968	0.000
H70.9 Mastoiditis, unspecified	0.032	0.968	0.000
H73.8 Other specified disorders of tympanic membrane	0.032	0.968	0.000
H74.0 Tympanosclerosis	0.032	0.968	0.000
H70.8 Other mastoiditis and related conditions	0.031	0.969	0.000
H70.2 Petrositis	0.031	0.969	0.000
H70.1 Chronic mastoiditis	0.031	0.969	0.000
H70.0 Acute mastoiditis	0.031	0.969	0.000
H73.1 Chronic myringitis	0.031	0.969	0.000
H73.0 Acute myringitis	0.031	0.969	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.031	0.969	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.030	0.969	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.030	0.969	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.030	0.969	0.000
H68.1 Obstruction of Eustachian tube	0.030	0.969	0.000
H68.0 Eustachian salpingitis	0.030	0.969	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.030	0.969	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.030	0.969	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.030	0.970	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.030	0.970	0.000
H60-H62 Diseases of external ear	0.030	0.970	0.000
H90.5 Sensorineural hearing loss, unspecified	0.030	0.970	0.000
H65 Nonsuppurative otitis media	0.030	0.970	0.000
H90.2 Conductive hearing loss, unspecified	0.029	0.971	0.000
T91 Sequelae of injuries of neck and trunk	0.029	0.971	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.029	0.971	0.000
T91.3 Sequelae of injury of spinal cord	0.029	0.971	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.029	0.971	0.000
H92 Otalgia and effusion of ear	0.029	0.971	0.000
C44.1 Skin of eyelid, including canthus	0.028	0.972	0.000
T90 Sequelae of injuries of head	0.028	0.972	0.000
T92 Sequelae of injuries of upper limb	0.027	0.973	0.000
H90.0 Conductive hearing loss, bilateral	0.027	0.973	0.000
C44.3 Skin of other and unspecified parts of face	0.027	0.973	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.026	0.973	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.026	0.974	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.026	0.974	0.000
T93 Sequelae of injuries of lower limb	0.026	0.974	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.025	0.974	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.025	0.975	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.025	0.975	0.000
H69.8 Other specified disorders of Eustachian tube	0.025	0.975	0.000
H69.0 Patulous Eustachian tube	0.024	0.975	0.000
T92.1 Sequelae of fracture of arm	0.024	0.976	0.000
T91.1 Sequelae of fracture of spine	0.024	0.976	0.000
T93.2 Sequelae of other fractures of lower limb	0.024	0.976	0.000
H80-H83 Diseases of inner ear	0.023	0.976	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.023	0.976	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.023	0.977	0.000
H61 Other disorders of external ear	0.023	0.977	0.000
H92.0 Otalgia	0.023	0.977	0.000
H65.2 Chronic serous otitis media	0.023	0.977	0.000
H60 Otitis externa	0.023	0.977	0.000
T90.4 Sequelae of injury of eye and orbit	0.023	0.977	0.000
H93 Other disorders of ear, not elsewhere classified	0.023	0.977	0.000
T90.5 Sequelae of intracranial injury	0.023	0.977	0.000
H91 Other hearing loss	0.023	0.977	0.000
T98 Sequelae of other and unspecified effects of external causes	0.022	0.978	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.022	0.978	0.000
H65.0 Acute serous otitis media	0.022	0.978	0.000
H92.1 Otorrhoea	0.022	0.978	0.000
T92.4 Sequelae of injury of nerve of upper limb	0.022	0.978	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.022	0.978	0.000
H80 Otosclerosis	0.021	0.978	0.000
H74.4 Polyp of middle ear	0.021	0.979	0.000
H65.1 Other acute nonsuppurative otitis media	0.021	0.979	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.021	0.979	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.021	0.979	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.021	0.979	0.000
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.021	0.979	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.021	0.979	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.021	0.979	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.021	0.979	0.000
T95 Sequelae of burns, corrosions and frostbite	0.021	0.979	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.021	0.979	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.021	0.979	0.000
T90.8 Sequelae of other specified injuries of head	0.021	0.979	0.000
H92.2 Otorrhagia	0.021	0.979	0.000
H61.2 Impacted cerumen	0.020	0.980	0.000
H80.9 Otosclerosis, unspecified	0.020	0.980	0.000
H65.4 Other chronic nonsuppurative otitis media	0.020	0.980	0.000
T91.2 Sequelae of other fracture of thorax and pelvis	0.020	0.980	0.000
T90.3 Sequelae of injury of cranial nerves	0.020	0.980	0.000
T90.1 Sequelae of open wound of head	0.020	0.980	0.000
T90.0 Sequelae of superficial injury of head	0.020	0.980	0.000
H90.3 Sensorineural hearing loss, bilateral	0.020	0.980	0.000
H60.0 Abscess of external ear	0.020	0.980	0.000
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.020	0.980	0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.020	0.980	0.000
T92.8 Sequelae of other specified injuries of upper limb	0.020	0.980	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.019	0.981	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.019	0.981	0.000
T92.0 Sequelae of open wound of upper limb	0.019	0.981	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.019	0.981	0.000
T93.4 Sequelae of injury of nerve of lower limb	0.019	0.981	0.000
T93.0 Sequelae of open wound of lower limb	0.019	0.981	0.000
H61.3 Acquired stenosis of external ear canal	0.019	0.981	0.000
C43 Malignant melanoma of skin	0.019	0.981	0.000
H60.5 Acute otitis externa, non-infective	0.019	0.981	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.018	0.981	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.018	0.981	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.018	0.981	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.018	0.982	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.018	0.982	0.000
H95.1 Other disorders following mastoidectomy	0.018	0.982	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.018	0.982	0.000
H60.3 Other infective otitis externa	0.018	0.982	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.018	0.982	0.000
H61.8 Other specified disorders of external ear	0.018	0.982	0.000
T93.1 Sequelae of fracture of femur	0.018	0.982	0.000
T92.2 Sequelae of fracture at wrist and hand level	0.018	0.982	0.000
H60.8 Other otitis externa	0.017	0.982	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.017	0.983	0.000
C43.3 Malignant melanoma of other and unspecified parts of face	0.017	0.983	0.000
H91.1 Presbycusis	0.017	0.983	0.000
H93.1 Tinnitus	0.017	0.983	0.000
H60.4 Cholesteatoma of external ear	0.016	0.983	0.000
H60.2 Malignant otitis externa	0.016	0.983	0.000
T90.9 Sequelae of unspecified injury of head	0.016	0.983	0.000
H93.3 Disorders of acoustic nerve	0.016	0.983	0.000
H93.2 Other abnormal auditory perceptions	0.016	0.983	0.000
H93.0 Degenerative and vascular disorders of ear	0.016	0.983	0.000
H91.3 Deaf mutism, not elsewhere classified	0.016	0.983	0.000
H91.2 Sudden idiopathic hearing loss	0.016	0.983	0.000
H91.0 Ototoxic hearing loss	0.016	0.983	0.000
T93.8 Sequelae of other specified injuries of lower limb	0.016	0.984	0.000
H91.9 Hearing loss, unspecified	0.016	0.984	0.000
T98.2 Sequelae of certain early complications of trauma	0.016	0.984	0.000
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.016	0.984	0.000
H93.8 Other specified disorders of ear	0.016	0.984	0.000
H61.9 Disorder of external ear, unspecified	0.016	0.984	0.000
H69.9 Eustachian tube disorder, unspecified	0.016	0.984	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.016	0.984	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.016	0.984	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
H62.2 Otitis externa in mycoses	0.016	0.984	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.016	0.984	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.016	0.984	0.000
H80.8 Other otosclerosis	0.016	0.984	0.000
H80.2 Cochlear otosclerosis	0.016	0.984	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.016	0.984	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.016	0.984	0.000
T98.1 Sequelae of other and unspecified effects of external causes	0.015	0.984	0.000
C43.6 Malignant melanoma of upper limb, including shoulder	0.016	0.984	0.000
H61.1 Non-infective disorders of pinna	0.015	0.984	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.015	0.985	0.000
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.015	0.985	0.000
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.015	0.985	0.000
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.015	0.985	0.000
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.015	0.985	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.015	0.985	0.000
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.015	0.985	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.015	0.985	0.000
H60.1 Cellulitis of external ear	0.015	0.985	0.000
N30.9 Cystitis, unspecified	0.000	0.985	0.015
C43.9 Malignant melanoma of skin, unspecified	0.015	0.985	0.000
C43.4 Malignant melanoma of scalp and neck	0.015	0.985	0.000
H93.9 Disorder of ear, unspecified	0.014	0.986	0.000
C43.8 Overlapping malignant melanoma of skin	0.014	0.986	0.000
C43.2 Malignant melanoma of ear and external auricular canal	0.014	0.986	0.000
C43.1 Malignant melanoma of eyelid, including canthus	0.014	0.986	0.000
C43.0 Malignant melanoma of lip	0.014	0.986	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.013	0.987	0.000
H91.8 Other specified hearing loss	0.013	0.987	0.000
H65.3 Chronic mucoid otitis media	0.013	0.987	0.000
H83 Other diseases of inner ear	0.012	0.988	0.000
C44.4 Skin of scalp and neck	0.011	0.989	0.000
H61.0 Perichondritis of external ear	0.010	0.990	0.000
T94.1 Sequelae of injuries, not specified by body region	0.010	0.990	0.000
H83.8 Other specified diseases of inner ear	0.009	0.991	0.000
H83.9 Disease of inner ear, unspecified	0.009	0.991	0.000
H83.3 Noise effects on inner ear	0.009	0.991	0.000
H83.2 Labyrinthine dysfunction	0.009	0.991	0.000
H83.1 Labyrinthine fistula	0.009	0.991	0.000
H81 Disorders of vestibular function	0.007	0.993	0.000
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.994	0.006
H60.9 Otitis externa, unspecified	0.005	0.994	0.001
H81.9 Disorder of vestibular function, unspecified	0.005	0.995	0.000
H81.8 Other disorders of vestibular function	0.005	0.995	0.000
H81.4 Vertigo of central origin	0.005	0.995	0.000
H81.3 Other peripheral vertigo	0.005	0.995	0.000
N30 Cystitis	0.000	0.995	0.005
G93.4 Encephalopathy, unspecified	0.005	0.995	0.000
G93.8 Other specified disorders of brain	0.005	0.995	0.000
K86.3 Pseudocyst of pancreas	0.000	0.995	0.005
M54.9 Dorsalgia, unspecified	0.000	0.996	0.004
C43.5 Malignant melanoma of trunk	0.004	0.996	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.996	0.004
M54.22 Cervicalgia (Cervical region)	0.000	0.996	0.004
G93 Other disorders of brain	0.004	0.996	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.004	0.996	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.996	0.004
H81.2 Vestibular neuronitis	0.004	0.996	0.000
K86 Other diseases of pancreas	0.000	0.996	0.004
G93.0 Cerebral cysts	0.004	0.996	0.000
N30.3 Trigonitis	0.000	0.996	0.004
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.996	0.004
R45.8 Other symptoms and signs involving emotional state	0.004	0.996	0.000
H81.0 Meniere's disease	0.004	0.996	0.000
M20.2 Hallux rigidus	0.004	0.996	0.000
N30.8 Other cystitis	0.000	0.996	0.004
N30.0 Acute cystitis	0.000	0.996	0.004
I86.4 Gastric varices	0.004	0.996	0.000
K86.2 Cyst of pancreas	0.000	0.996	0.004
N30.2 Other chronic cystitis	0.000	0.996	0.004
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.996	0.004
L53.9 Erythematous condition, unspecified	0.004	0.996	0.000
K14.0 Glossitis	0.003	0.997	0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.997	0.003
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.997	0.003
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.997	0.003
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.997	0.003
G93.3 Postviral fatigue syndrome	0.003	0.997	0.000
K86.1 Other chronic pancreatitis	0.000	0.997	0.003
K86.8 Other specified diseases of pancreas	0.000	0.997	0.003
G93.7 Reye's syndrome	0.003	0.997	0.000
M54.2 Cervicalgia	0.000	0.997	0.003
G93.2 Benign intracranial hypertension	0.003	0.997	0.000
T18.1 Foreign body in oesophagus	0.000	0.997	0.003
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
I86.8 Varicose veins of other specified sites	0.003	0.997	0.000
N30.4 Irradiation cystitis	0.000	0.997	0.003
N30.1 Interstitial cystitis (chronic)	0.000	0.997	0.003
D68.8 Other specified coagulation defects	0.000	0.997	0.003
C43.7 Malignant melanoma of lower limb, including hip	0.003	0.997	0.001
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts	0.000	0.997	0.003
G61.0 Guillain-Barre syndrome	0.003	0.997	0.000
T39.1 4-Aminophenol derivatives	0.003	0.997	0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.997	0.003
G93.5 Compression of brain	0.003	0.997	0.000
K86.9 Disease of pancreas, unspecified	0.000	0.997	0.003
D68.2 Hereditary deficiency of other clotting factors	0.000	0.997	0.003
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.997	0.003
H40.9 Glaucoma, unspecified	0.003	0.997	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.997	0.003
D68 Other coagulation defects	0.000	0.997	0.003
D68.5 Primary Thrombophilia	0.000	0.997	0.003
H83.0 Labyrinthitis	0.002	0.997	0.000
M54 Dorsalgia	0.000	0.997	0.003
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.997	0.002
M54.27 Cervicalgia-Lumbosacral	0.000	0.997	0.002
M54.26 Cervicalgia-Lumbar	0.000	0.997	0.002
M54.25 Cervicalgia-Thoracolumbar	0.000	0.997	0.002
M54.24 Cervicalgia-Thoracic	0.000	0.997	0.002
M54.21 Cervicalgia (Occipito-atlanto-axial region)	0.000	0.997	0.002
M54.20 Cervicalgia-Mult site	0.000	0.997	0.002
M54.29 Cervicalgia-Site unspe	0.000	0.997	0.002
M54.23 Cervicalgia (Cervicothoracic region)	0.000	0.997	0.002
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
Y42.5 Other oestrogens and progestogens	0.000	0.998	0.002
I86 Varicose veins of other sites	0.002	0.998	0.000
H40.2 Primary angle-closure glaucoma	0.002	0.998	0.000
M54.6 Pain in thoracic spine	0.000	0.998	0.002
M54.4 Lumbago with sciatica	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
O82.0 Delivery by elective Caesarean section	0.002	0.998	0.000
D68.6 Other Thrombophilia	0.000	0.998	0.002
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
G61 Inflammatory polyneuropathy	0.002	0.998	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
L53 Other erythematous conditions	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
G93.6 Cerebral oedema	0.002	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.002	0.998	0.000
S42.00 Fracture of clavicle (closed)	0.002	0.998	0.000
R50.0 Fever with chills	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
G93.9 Disorder of brain, unspecified	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
M54.0 Panniculitis affecting regions of neck and back	0.000	0.998	0.002
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
S92.0 Fracture of calcaneus	0.002	0.998	0.000
I86.2 Pelvic varices	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
M54.8 Other dorsalgia	0.000	0.998	0.002
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
H40 Glaucoma	0.002	0.998	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.002	0.998	0.000
I87.8 Other specified disorders of veins	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
I86.3 Vulval varices	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
M54.47 Lumbago with sciatica (Lumbosacral region)	0.000	0.998	0.002
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
E55.9 Vitamin D deficiency, unspecified	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.002	0.998	0.000
Z87.0 Personal history of diseases of the respiratory system	0.002	0.998	0.000
M54.69 Pain in thoracic spine-Site unspe	0.000	0.998	0.002
M54.68 Pain in thoracic spine-Sacral/sacrococ	0.000	0.998	0.002
M54.67 Pain in thoracic spine-Lumbosacral	0.000	0.998	0.002
M54.66 Pain in thoracic spine-Lumbar	0.000	0.998	0.002
M54.65 Pain in thoracic spine (Thoracolumbar region)	0.000	0.998	0.002
M54.63 Pain in thoracic spine (Cervicothoracic region)	0.000	0.998	0.002
M54.62 Pain in thoracic spine-Cervical	0.000	0.998	0.002
M54.61 Pain in thoracic spine-Occipit-atl-axl	0.000	0.998	0.002
M54.60 Pain in thoracic spine (Multiple sites in spine)	0.000	0.998	0.002
S02.30 Fracture of orbital floor (closed)	0.000	0.998	0.002
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.45 Lumbago with sciatica (Thoracolumbar region)	0.000	0.998	0.002
M54.44 Lumbago with sciatica-Thoracic	0.000	0.998	0.002
M54.43 Lumbago with sciatica-Cervicothoracic	0.000	0.998	0.002
M54.42 Lumbago with sciatica-Cervical	0.000	0.998	0.002
M54.41 Lumbago with sciatica-Occipit-atl-axl	0.000	0.998	0.002
M54.40 Lumbago with sciatica (Multiple sites in spine)	0.000	0.998	0.002
D68.0 Von Willebrand's disease	0.000	0.998	0.002
S92.5 Fracture of other toe	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.002
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
H40.0 Glaucoma suspect	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
G61.8 Other inflammatory polyneuropathies	0.002	0.998	0.000
G61.1 Serum neuropathy	0.002	0.998	0.000
H40.8 Other glaucoma	0.002	0.998	0.000
F31 Bipolar affective disorder	0.002	0.998	0.000
L53.3 Other chronic figurate erythema	0.002	0.998	0.000
L53.2 Erythema marginatum	0.002	0.998	0.000
L53.1 Erythema annulare centrifugum	0.002	0.998	0.000
L53.0 Toxic erythema	0.002	0.998	0.000
M54.1 Radiculopathy	0.000	0.998	0.002
H40.3 Glaucoma secondary to eye trauma	0.002	0.998	0.000
S83.2 Tear of meniscus, current	0.000	0.998	0.002
T39.4 Antirheumatics, not elsewhere classified	0.002	0.998	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.002	0.998	0.000
T39.2 Pyrazolone derivatives	0.002	0.998	0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)	0.000	0.998	0.002
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)	0.000	0.998	0.002
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)	0.000	0.998	0.002
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)	0.000	0.998	0.002
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)	0.000	0.998	0.002
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)	0.000	0.998	0.002
M54.02 Panniculitis affecting regions of neck and back (Cervical region)	0.000	0.998	0.002
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)	0.000	0.998	0.002
M54.16 Radiculopathy (Lumbar region)	0.000	0.998	0.002
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
Y85.0 Sequelae of motor-vehicle accident	0.002	0.998	0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)	0.000	0.998	0.002
M54.87 Other dorsalgia (Lumbosacral region)	0.000	0.998	0.002
M54.86 Other dorsalgia (Lumbar region)	0.000	0.998	0.002
M54.85 Other dorsalgia (Thoracolumbar region)	0.000	0.998	0.002
M54.84 Other dorsalgia (Thoracic region)	0.000	0.998	0.002
M54.83 Other dorsalgia (Cervicothoracic region)	0.000	0.998	0.002
M54.82 Other dorsalgia (Cervical region)	0.000	0.998	0.002
M54.81 Other dorsalgia (Occipito-atlanto-axial region)	0.000	0.998	0.002
M54.80 Other dorsalgia (Multiple sites in spine)	0.000	0.998	0.002
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
H40.6 Glaucoma secondary to drugs	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
H40.4 Glaucoma secondary to eye inflammation	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.002	0.998	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.002	0.998	0.000
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
F31.9 Bipolar affective disorder, unspecified	0.002	0.998	0.000
L51.1 Bullous erythema multiforme	0.002	0.998	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
S92.3 Fracture of metatarsal bone	0.002	0.998	0.000
Y95 Nosocomial condition	0.002	0.998	0.000
M54.89 Other dorsalgia (Site unspecified)	0.000	0.998	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
Q89.2 Congenital malformations of other endocrine glands	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.001	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.998	0.001
F31.8 Other bipolar affective disorders	0.002	0.998	0.000
M54.17 Radiculopathy (Lumbosacral region)	0.000	0.998	0.001
M54.15 Radiculopathy (Thoracolumbar region)	0.000	0.998	0.001
M54.13 Radiculopathy (Cervicothoracic region)	0.000	0.998	0.001
M54.11 Radiculopathy (Occipito-atlanto-axial region)	0.000	0.998	0.001
M54.10 Radiculopathy (Multiple sites in spine)	0.000	0.998	0.001
N13.9 Obstructive and reflux uropathy, unspecified	0.002	0.998	0.000
L51 Erythema multiforme	0.002	0.998	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.002	0.998	0.000
I47.1 Supraventricular tachycardia	0.000	0.998	0.002
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.002	0.998	0.000
L53.8 Other specified erythematous conditions	0.001	0.998	0.000
O82.1 Delivery by emergency Caesarean section	0.002	0.998	0.000
Z97.5 Presence of (intra-uterine) contraceptive device	0.000	0.998	0.002
T46.1 Calcium-channel blockers	0.001	0.998	0.000
G25 Other extrapyramidal and movement disorders	0.000	0.998	0.002
S92.71 Multiple fractures of foot (open)	0.001	0.998	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.001	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.001	0.998	0.000
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
H40.5 Glaucoma secondary to other eye disorders	0.001	0.998	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.001	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
L50-L54 Urticaria and erythema	0.002	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.001	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.001
Q89 Other congenital malformations, not elsewhere classified	0.001	0.998	0.000
M54.14 Radiculopathy (Thoracic region)	0.000	0.998	0.001
S92.31 Fracture of metatarsal bone (open)	0.001	0.998	0.000
Q87.0 Congenital malformation syndromes predominantly affecting facial appearance	0.001	0.998	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.001	0.998	0.000
G25.3 Myoclonus	0.000	0.999	0.001
T18 Foreign body in alimentary tract	0.000	0.999	0.001
T46 Poisoning by agents primarily affecting the cardiovascular system	0.001	0.999	0.000
S42.10 Fracture of scapula (closed)	0.000	0.999	0.001
R44.1 Visual hallucinations	0.000	0.999	0.001
I50.1 Left ventricular failure	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.001	0.999	0.000
S83.7 Injury to multiple structures of knee	0.000	0.999	0.001
S83.3 Tear of articular cartilage of knee, current	0.000	0.999	0.001
S83.1 Dislocation of knee	0.000	0.999	0.001
S83.0 Dislocation of patella	0.000	0.999	0.001
T86.1 Kidney transplant failure and rejection	0.001	0.999	0.000
O82 Single delivery by Caesarean section	0.001	0.999	0.000
R45 Symptoms and signs involving emotional state	0.001	0.999	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.001	0.999	0.000
M54.56 Low back pain (Lumbar region)	0.000	0.999	0.001
G55.1 Nerve root and plexus compressions in intervertebral disk disorders	0.000	0.999	0.001
L51.9 Erythema multiforme, unspecified	0.001	0.999	0.000
L51.8 Other erythema multiforme	0.001	0.999	0.000
L51.2 Toxic epidermal necrolysis [Lyell]	0.001	0.999	0.000
L51.0 Nonbullous erythema multiforme	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
L52 Erythema nodosum	0.001	0.999	0.000
Q82 Other congenital malformations of skin	0.001	0.999	0.000
J94.1 Fibrothorax	0.001	0.999	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.999	0.001
T38.9 Other and unspecified hormone antagonists	0.001	0.999	0.000
T38.7 Androgens and anabolic congeners	0.001	0.999	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.001	0.999	0.000
T38.5 Other oestrogens and progestogens	0.001	0.999	0.000
T38.4 Oral contraceptives	0.001	0.999	0.000
T38.2 Antithyroid drugs	0.001	0.999	0.000
T38.1 Thyroid hormones and substitutes	0.001	0.999	0.000
T38.0 Glucocorticoids and synthetic analogues	0.001	0.999	0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems	0.001	0.999	0.000
Q82.8 Other specified congenital malformations of skin	0.001	0.999	0.000
Z91.5 Personal history of self-harm	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.999	0.001
G25.5 Other chorea	0.000	0.999	0.001
G25.4 Drug-induced chorea	0.000	0.999	0.001
G25.1 Drug-induced tremor	0.000	0.999	0.001
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.000	0.999	0.001
T46.5 Other antihypertensive drugs, not elsewhere classified	0.001	0.999	0.000
J94 Other pleural conditions	0.001	0.999	0.000
L50 Urticaria	0.001	0.999	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999	0.000
S92.30 Fracture of metatarsal bone (closed)	0.001	0.999	0.000
G63.2 Diabetic polyneuropathy	0.001	0.999	0.000
G95.1 Vascular myelopathies	0.001	0.999	0.000
L54 Erythema in diseases classified elsewhere	0.001	0.999	0.000
M00.96 Pyogenic arthritis, unspecified (Lower leg)	0.001	0.999	0.000
I49.5 Sick sinus syndrome	0.000	0.999	0.001
L50.9 Urticaria, unspecified	0.001	0.999	0.000
Q89.9 Congenital malformation, unspecified	0.001	0.999	0.000
Q89.8 Other specified congenital malformations	0.001	0.999	0.000
Q89.7 Multiple congenital malformations, not elsewhere classified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations