TreeWAS – Variant ID: rs11998763

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.068	0.932	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.063	0.937	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.056	0.944	0.000
M80 Osteoporosis with pathological fracture	0.054	0.946	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.052	0.948	0.000
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.051	0.949	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.050	0.950	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.046	0.954	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.046	0.954	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.046	0.954	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.046	0.954	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.046	0.954	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.046	0.954	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.043	0.957	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.042	0.958	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.040	0.959	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.040	0.960	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.039	0.961	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.039	0.961	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.039	0.961	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.038	0.962	0.000
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.038	0.962	0.000
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.038	0.962	0.000
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.038	0.962	0.000
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.038	0.962	0.000
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.038	0.962	0.000
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.038	0.962	0.000
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.038	0.962	0.000
M80.8 Other osteoporosis with pathological fracture	0.035	0.965	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.033	0.967	0.000
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.031	0.969	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.030	0.970	0.000
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.030	0.970	0.000
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.030	0.970	0.000
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.030	0.970	0.000
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.030	0.970	0.000
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.030	0.970	0.000
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.030	0.970	0.000
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.030	0.970	0.000
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.030	0.970	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.029	0.971	0.000
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.029	0.971	0.000
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.029	0.971	0.000
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.029	0.971	0.000
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.029	0.971	0.000
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.029	0.971	0.000
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.029	0.971	0.000
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.029	0.971	0.000
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.029	0.971	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.028	0.972	0.000
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.028	0.972	0.000
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.028	0.972	0.000
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.028	0.972	0.000
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.028	0.972	0.000
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.028	0.972	0.000
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.028	0.972	0.000
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.028	0.972	0.000
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.028	0.972	0.000
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.028	0.972	0.000
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.028	0.972	0.000
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.028	0.972	0.000
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.028	0.972	0.000
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.028	0.972	0.000
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.028	0.972	0.000
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.028	0.972	0.000
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.028	0.972	0.000
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.028	0.972	0.000
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.028	0.972	0.000
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.028	0.972	0.000
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.028	0.972	0.000
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.028	0.972	0.000
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.028	0.972	0.000
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.028	0.972	0.000
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.028	0.972	0.000
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.028	0.972	0.000
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.028	0.972	0.000
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.028	0.972	0.000
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.028	0.972	0.000
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.028	0.972	0.000
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.025	0.975	0.000
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.025	0.975	0.000
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.025	0.975	0.000
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.025	0.975	0.000
M80.84 Other osteoporosis with pathological fracture (Hand)	0.025	0.975	0.000
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.025	0.975	0.000
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.025	0.975	0.000
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.025	0.975	0.000
M80.88 Other osteoporosis with pathological fracture (Other)	0.023	0.976	0.000
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.023	0.977	0.000
I20.0 Unstable angina	0.000	0.981	0.019
I24.8 Other forms of acute ischaemic heart disease	0.000	0.990	0.010
C16.0 Cardia	0.000	0.992	0.008
D05.9 Carcinoma in situ of breast, unspecified	0.008	0.992	0.000
M80-M85 Disorders of bone density and structure	0.007	0.993	0.000
C02.9 Tongue, unspecified	0.007	0.993	0.000
C16 Malignant neoplasm of stomach	0.000	0.993	0.007
C16.9 Stomach, unspecified	0.000	0.994	0.006
C02 Malignant neoplasm of other and unspecified parts of tongue	0.006	0.994	0.000
E55.9 Vitamin D deficiency, unspecified	0.006	0.994	0.000
C16.6 Greater curvature of stomach, unspecified	0.000	0.994	0.006
M83 Adult osteomalacia	0.006	0.994	0.000
C16.1 Fundus of stomach	0.000	0.994	0.006
M85 Other disorders of bone density and structure	0.006	0.994	0.000
M82 Osteoporosis in diseases classified elsewhere	0.006	0.994	0.000
C16.3 Pyloric antrum	0.000	0.995	0.005
C10.9 Oropharynx, unspecified	0.005	0.995	0.000
C16.2 Body of stomach	0.000	0.995	0.005
M85.0 Fibrous dysplasia (monostotic)	0.005	0.995	0.000
C02.1 Border of tongue	0.005	0.995	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.005	0.995	0.000
C16.4 Pylorus	0.000	0.995	0.005
C02.8 Overlapping lesion of tongue	0.005	0.995	0.000
M85.2 Hyperostosis of skull	0.005	0.995	0.000
C16.8 Overlapping lesion of stomach	0.000	0.995	0.005
F80.1 Expressive language disorder	0.000	0.995	0.005
M83.3 Adult osteomalacia due to malnutrition	0.004	0.995	0.000
M83.8 Other adult osteomalacia	0.004	0.995	0.000
C10 Malignant neoplasm of oropharynx	0.004	0.995	0.000
C02.2 Ventral surface of tongue	0.004	0.995	0.000
C02.3 Anterior two-thirds of tongue, part unspecified	0.004	0.996	0.000
C02.0 Dorsal surface of tongue	0.004	0.996	0.000
M82.1 Osteoporosis in endocrine disorders	0.004	0.996	0.000
M85.4 Solitary bone cyst	0.004	0.996	0.000
M85.20 Hyperostosis of skull-Mult sites	0.004	0.996	0.000
M83.9 Adult osteomalacia, unspecified	0.004	0.996	0.000
M83.5 Other drug-induced osteomalacia in adults	0.004	0.996	0.000
M83.4 Aluminum bone disease	0.004	0.996	0.000
M83.2 Adult osteomalacia due to malabsorption	0.004	0.996	0.000
M83.0 Puerperal osteomalacia	0.004	0.996	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.004	0.996	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.004	0.996	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.004	0.996	0.000
M85.5 Aneurysmal bone cyst	0.004	0.996	0.000
M85.3 Osteitis condensans	0.004	0.996	0.000
M85.1 Skeletal fluorosis	0.004	0.996	0.000
C16.5 Lesser curvature of stomach, unspecified	0.000	0.996	0.004
M85.22 Hyperostosis of skull-Upper arm	0.004	0.996	0.000
N30.1 Interstitial cystitis (chronic)	0.004	0.996	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.004	0.996	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.004	0.996	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.004	0.996	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.004	0.996	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.004	0.996	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.004	0.996	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.004	0.996	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.004	0.996	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.004	0.996	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.004	0.996	0.000
B02.9 Zoster without complication	0.000	0.996	0.004
M83.1 Senile osteomalacia	0.004	0.996	0.000
C02.4 Lingual tonsil	0.004	0.996	0.000
M85.9 Disorder of bone density and structure, unspecified	0.004	0.996	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.004	0.996	0.000
M85.29 Hyperostosis of skull-Site unspec	0.004	0.996	0.000
M85.28 Hyperostosis of skull-Other	0.004	0.996	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.004	0.996	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.004	0.996	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.004	0.996	0.000
M85.24 Hyperostosis of skull-Hand	0.004	0.996	0.000
M85.23 Hyperostosis of skull-Forearm	0.004	0.996	0.000
M85.21 Hyperostosis of skull-Shldr region	0.004	0.996	0.000
C04 Malignant neoplasm of floor of mouth	0.004	0.996	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.004	0.996	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.996	0.004
M83.80 Other adult osteomalacia (Multiple sites)	0.003	0.996	0.000
M85.46 Solitary bone cyst (Lower leg)	0.003	0.996	0.000
S41.1 Open wound of upper arm	0.004	0.996	0.000
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.003	0.996	0.000
M83.38 Adult osteomalacia due to malnutrition (Other)	0.003	0.996	0.000
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.003	0.996	0.000
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.003	0.996	0.000
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.003	0.996	0.000
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.003	0.996	0.000
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.003	0.996	0.000
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.003	0.996	0.000
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.003	0.996	0.000
C04.0 Anterior floor of mouth	0.003	0.996	0.000
E55 Vitamin D deficiency	0.004	0.996	0.000
M85.6 Other cyst of bone	0.003	0.996	0.000
M83.89 Other adult osteomalacia (Site unspecified)	0.003	0.996	0.000
M83.88 Other adult osteomalacia (Other)	0.003	0.996	0.000
M83.87 Other adult osteomalacia (Ankle and foot)	0.003	0.996	0.000
M83.86 Other adult osteomalacia (Lower leg)	0.003	0.996	0.000
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.003	0.996	0.000
M83.84 Other adult osteomalacia (Hand)	0.003	0.996	0.000
M83.83 Other adult osteomalacia (Forearm)	0.003	0.996	0.000
M83.82 Other adult osteomalacia (Upper arm)	0.003	0.996	0.000
M83.81 Other adult osteomalacia (Shoulder region)	0.003	0.996	0.000
C10.8 Overlapping lesion of oropharynx	0.003	0.996	0.000
C10.4 Branchial cleft	0.003	0.996	0.000
C10.3 Posterior wall of oropharynx	0.003	0.996	0.000
C10.2 Lateral wall of oropharynx	0.003	0.996	0.000
C10.1 Anterior surface of epiglottis	0.003	0.996	0.000
C10.0 Vallecula	0.003	0.996	0.000
C04.9 Floor of mouth, unspecified	0.003	0.997	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.003	0.997	0.000
M82.18 Osteoporosis in endocrine disorders (Other)	0.003	0.997	0.000
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.003	0.997	0.000
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.003	0.997	0.000
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.003	0.997	0.000
M82.14 Osteoporosis in endocrine disorders (Hand)	0.003	0.997	0.000
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.003	0.997	0.000
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.003	0.997	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.997	0.003
M85.47 Solitary bone cyst (Ankle and foot)	0.003	0.997	0.000
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.997	0.003
M85.49 Solitary bone cyst (Site unspecified)	0.003	0.997	0.000
M85.48 Solitary bone cyst (Other)	0.003	0.997	0.000
M85.44 Solitary bone cyst (Hand)	0.003	0.997	0.000
M85.43 Solitary bone cyst (Forearm)	0.003	0.997	0.000
M85.42 Solitary bone cyst (Upper arm)	0.003	0.997	0.000
M85.41 Solitary bone cyst (Shoulder region)	0.003	0.997	0.000
M85.40 Solitary bone cyst (Multiple sites)	0.003	0.997	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.003	0.997	0.000
M83.08 Puerperal osteomalacia (Other)	0.003	0.997	0.000
M83.07 Puerperal osteomalacia (Ankle and foot)	0.003	0.997	0.000
M83.06 Puerperal osteomalacia (Lower leg)	0.003	0.997	0.000
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.003	0.997	0.000
M83.04 Puerperal osteomalacia (Hand)	0.003	0.997	0.000
M83.03 Puerperal osteomalacia (Forearm)	0.003	0.997	0.000
M83.02 Puerperal osteomalacia (Upper arm)	0.003	0.997	0.000
M83.01 Puerperal osteomalacia (Shoulder region)	0.003	0.997	0.000
M83.00 Puerperal osteomalacia (Multiple sites)	0.003	0.997	0.000
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.003	0.997	0.000
M83.28 Adult osteomalacia due to malabsorption (Other)	0.003	0.997	0.000
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.003	0.997	0.000
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.003	0.997	0.000
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.003	0.997	0.000
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.003	0.997	0.000
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.003	0.997	0.000
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.003	0.997	0.000
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.003	0.997	0.000
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.003	0.997	0.000
M83.49 Aluminium bone disease (Site unspecified)	0.003	0.997	0.000
M83.48 Aluminium bone disease (Other)	0.003	0.997	0.000
M83.47 Aluminium bone disease (Ankle and foot)	0.003	0.997	0.000
M83.46 Aluminium bone disease (Lower leg)	0.003	0.997	0.000
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.003	0.997	0.000
M83.44 Aluminium bone disease (Hand)	0.003	0.997	0.000
M83.43 Aluminium bone disease (Forearm)	0.003	0.997	0.000
M83.42 Aluminium bone disease (Upper arm)	0.003	0.997	0.000
M83.41 Aluminium bone disease (Shoulder region)	0.003	0.997	0.000
M83.40 Aluminium bone disease (Multiple sites)	0.003	0.997	0.000
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.003	0.997	0.000
M83.58 Other drug-induced osteomalacia in adults (Other)	0.003	0.997	0.000
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.003	0.997	0.000
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.003	0.997	0.000
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.003	0.997	0.000
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.003	0.997	0.000
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.003	0.997	0.000
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.003	0.997	0.000
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.003	0.997	0.000
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.003	0.997	0.000
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.003	0.997	0.000
M83.98 Adult osteomalacia, unspecified (Other)	0.003	0.997	0.000
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.003	0.997	0.000
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.003	0.997	0.000
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M83.94 Adult osteomalacia, unspecified (Hand)	0.003	0.997	0.000
M83.93 Adult osteomalacia, unspecified (Forearm)	0.003	0.997	0.000
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.003	0.997	0.000
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.003	0.997	0.000
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.003	0.997	0.000
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.003	0.997	0.000
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.003	0.997	0.000
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.003	0.997	0.000
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.003	0.997	0.000
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.003	0.997	0.000
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.003	0.997	0.000
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.003	0.997	0.000
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.003	0.997	0.000
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.003	0.997	0.000
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.003	0.997	0.000
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.003	0.997	0.000
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.003	0.997	0.000
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.003	0.997	0.000
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.003	0.997	0.000
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.003	0.997	0.000
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.003	0.997	0.000
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.003	0.997	0.000
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.003	0.997	0.000
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.003	0.997	0.000
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.003	0.997	0.000
M85.19 Skeletal fluorosis (Site unspecified)	0.003	0.997	0.000
M85.18 Skeletal fluorosis (Other)	0.003	0.997	0.000
M85.17 Skeletal fluorosis (Ankle and foot)	0.003	0.997	0.000
M85.16 Skeletal fluorosis (Lower leg)	0.003	0.997	0.000
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.003	0.997	0.000
M85.14 Skeletal fluorosis (Hand)	0.003	0.997	0.000
M85.13 Skeletal fluorosis (Forearm)	0.003	0.997	0.000
M85.12 Skeletal fluorosis (Upper arm)	0.003	0.997	0.000
M85.11 Skeletal fluorosis (Shoulder region)	0.003	0.997	0.000
M85.10 Skeletal fluorosis (Multiple sites)	0.003	0.997	0.000
M85.39 Osteitis condensans (Site unspecified)	0.003	0.997	0.000
M85.38 Osteitis condensans (Other)	0.003	0.997	0.000
M85.37 Osteitis condensans (Ankle and foot)	0.003	0.997	0.000
M85.36 Osteitis condensans (Lower leg)	0.003	0.997	0.000
M85.35 Osteitis condensans (Pelvic region and thigh)	0.003	0.997	0.000
M85.34 Osteitis condensans (Hand)	0.003	0.997	0.000
M85.33 Osteitis condensans (Forearm)	0.003	0.997	0.000
M85.32 Osteitis condensans (Upper arm)	0.003	0.997	0.000
M85.31 Osteitis condensans (Shoulder region)	0.003	0.997	0.000
M85.30 Osteitis condensans (Multiple sites)	0.003	0.997	0.000
M85.59 Aneurysmal bone cyst (Site unspecified)	0.003	0.997	0.000
M85.58 Aneurysmal bone cyst (Other)	0.003	0.997	0.000
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.003	0.997	0.000
M85.56 Aneurysmal bone cyst (Lower leg)	0.003	0.997	0.000
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.54 Aneurysmal bone cyst (Hand)	0.003	0.997	0.000
M85.53 Aneurysmal bone cyst (Forearm)	0.003	0.997	0.000
M85.52 Aneurysmal bone cyst (Upper arm)	0.003	0.997	0.000
M85.51 Aneurysmal bone cyst (Shoulder region)	0.003	0.997	0.000
M85.50 Aneurysmal bone cyst (Multiple sites)	0.003	0.997	0.000
C08 Malignant neoplasm of other and unspecified major salivary glands	0.003	0.997	0.000
C00 Malignant neoplasm of lip	0.003	0.997	0.000
M83.19 Senile osteomalacia (Site unspecified)	0.003	0.997	0.000
M83.18 Senile osteomalacia (Other)	0.003	0.997	0.000
M83.17 Senile osteomalacia (Ankle and foot)	0.003	0.997	0.000
M83.16 Senile osteomalacia (Lower leg)	0.003	0.997	0.000
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.003	0.997	0.000
M83.14 Senile osteomalacia (Hand)	0.003	0.997	0.000
M83.13 Senile osteomalacia (Forearm)	0.003	0.997	0.000
M83.11 Senile osteomalacia (Shoulder region)	0.003	0.997	0.000
M83.10 Senile osteomalacia (Multiple sites)	0.003	0.997	0.000
F80 Specific developmental disorders of speech and language	0.000	0.997	0.003
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.003	0.997	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.003	0.997	0.000
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.003	0.997	0.000
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.003	0.997	0.000
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.003	0.997	0.000
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.003	0.997	0.000
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.003	0.997	0.000
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.003	0.997	0.000
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.003	0.997	0.000
K70.3 Alcoholic cirrhosis of liver	0.000	0.997	0.003
S41.0 Open wound of shoulder	0.003	0.997	0.000
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
C11 Malignant neoplasm of nasopharynx	0.003	0.997	0.000
I25.9 Chronic ischaemic heart disease, unspecified	0.000	0.997	0.003
C04.8 Overlapping lesion of floor of mouth	0.003	0.997	0.000
C04.1 Lateral floor of mouth	0.003	0.997	0.000
I44.0 Atrioventricular block, first degree	0.003	0.997	0.000
C07 Malignant neoplasm of parotid gland	0.003	0.997	0.000
C06 Malignant neoplasm of other and unspecified parts of mouth	0.003	0.997	0.000
C13 Malignant neoplasm of hypopharynx	0.003	0.997	0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx	0.003	0.997	0.000
C03 Malignant neoplasm of gum	0.003	0.997	0.000
M83.12 Senile osteomalacia (Upper arm)	0.003	0.997	0.000
M85.66 Other cyst of bone (Lower leg)	0.003	0.997	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.003	0.997	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.003	0.997	0.000
C08.0 Submandibular gland	0.003	0.997	0.000
E55.0 Rickets, active	0.003	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
M85.69 Other cyst of bone (Site unspecified)	0.003	0.997	0.000
M85.63 Other cyst of bone (Forearm)	0.003	0.997	0.000
M85.62 Other cyst of bone (Upper arm)	0.003	0.997	0.000
M85.61 Other cyst of bone (Shoulder region)	0.003	0.997	0.000
M85.60 Other cyst of bone (Multiple sites)	0.003	0.997	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.997	0.003
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.003	0.997	0.000
I24 Other acute ischaemic heart diseases	0.000	0.997	0.003
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.003	0.997	0.000
G82.2 Paraplegia, unspecified	0.003	0.997	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.997	0.000
M85.64 Other cyst of bone (Hand)	0.003	0.997	0.000
F80.2 Receptive language disorder	0.000	0.997	0.003
C12 Malignant neoplasm of pyriform sinus	0.003	0.997	0.000
S41 Open wound of shoulder and upper arm	0.003	0.997	0.000
C00.0 External upper lip	0.003	0.997	0.000
C00.1 External lower lip	0.003	0.997	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.003	0.997	0.000
M85.65 Other cyst of bone (Pelvic region and thigh)	0.003	0.997	0.000
I20 Angina pectoris	0.000	0.997	0.003
M54.16 Radiculopathy (Lumbar region)	0.000	0.997	0.003
C06.2 Retromolar area	0.003	0.997	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.997	0.003
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.003	0.997	0.000
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.002	0.997	0.000
C08.8 Overlapping lesion of major salivary glands	0.002	0.997	0.000
C08.1 Sublingual gland	0.002	0.997	0.000
C13.0 Postcricoid region	0.002	0.997	0.000
G82 Paraplegia and tetraplegia	0.003	0.997	0.000
A63.0 Anogenital (venereal) warts	0.003	0.997	0.000
C08.9 Major salivary gland, unspecified	0.002	0.997	0.000
C05 Malignant neoplasm of palate	0.002	0.997	0.000
C00.8 Overlapping lesion of lip	0.002	0.997	0.000
C00.6 Commissure of lip	0.002	0.997	0.000
C00.5 Lip, unspecified, inner aspect	0.002	0.997	0.000
C00.4 Lower lip, inner aspect	0.002	0.997	0.000
C00.3 Upper lip, inner aspect	0.002	0.997	0.000
C00.2 External lip, unspecified	0.002	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.003	0.997	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.000	0.997	0.002
F80.8 Other developmental disorders of speech and language	0.000	0.997	0.002
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.000	0.997	0.002
F80.0 Specific speech articulation disorder	0.000	0.997	0.002
M62.88 Other specified disorders of muscle (Other)	0.000	0.997	0.003
M85.68 Other cyst of bone (Other)	0.002	0.997	0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.997	0.003
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
C11.8 Overlapping lesion of nasopharynx	0.002	0.997	0.000
C11.3 Anterior wall of nasopharynx	0.002	0.997	0.000
C11.2 Lateral wall of nasopharynx	0.002	0.997	0.000
C11.1 Posterior wall of nasopharynx	0.002	0.997	0.000
C11.0 Superior wall of nasopharynx	0.002	0.997	0.000
C11.9 Nasopharynx, unspecified	0.002	0.997	0.000
G83.4 Cauda equina syndrome	0.002	0.997	0.000
C06.8 Overlapping lesion of other and unspecified parts of mouth	0.002	0.998	0.000
C06.1 Vestibule of mouth	0.002	0.998	0.000
G82.5 Tetraplegia, unspecified	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.002	0.998	0.000
G82.4 Spastic tetraplegia	0.002	0.998	0.000
Z72.2 Drug use	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
C13.8 Overlapping lesion of hypopharynx	0.002	0.998	0.000
C13.2 Posterior wall of hypopharynx	0.002	0.998	0.000
C13.1 Aryepiglottic fold, hypopharyngeal aspect	0.002	0.998	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.998	0.002
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
C01 Malignant neoplasm of base of tongue	0.002	0.998	0.000
C06.0 Cheek mucosa	0.002	0.998	0.000
C03.9 Gum, unspecified	0.002	0.998	0.000
C03.0 Upper gum	0.002	0.998	0.000
C14.8 Overlapping lesion of lip, oral cavity and pharynx	0.002	0.998	0.000
C14.2 Waldeyer's ring	0.002	0.998	0.000
G95.8 Other specified diseases of spinal cord	0.002	0.998	0.000
C00.9 Lip, unspecified	0.002	0.998	0.000
K55.2 Angiodysplasia of colon	0.000	0.998	0.002
G82.0 Flaccid paraplegia	0.002	0.998	0.000
I25.3 Aneurysm of heart	0.000	0.998	0.002
Z95.2 Presence of prosthetic heart valve	0.002	0.998	0.000
F84.5 Asperger's syndrome	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.002	0.998	0.000
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
I25 Chronic ischaemic heart disease	0.000	0.998	0.002
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.002	0.998	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.002	0.998	0.000
I20-I25 Ischaemic heart diseases	0.000	0.998	0.002
G41.9 Status epilepticus, unspecified	0.000	0.998	0.002
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.002	0.998	0.000
L85.8 Other specified epidermal thickening	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
C03.1 Lower gum	0.002	0.998	0.000
C05.1 Soft palate	0.002	0.998	0.000
C06.9 Mouth, unspecified	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.002	0.998	0.000
C14.0 Pharynx, unspecified	0.002	0.998	0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.002	0.998	0.000
I60 Subarachnoid haemorrhage	0.002	0.998	0.000
G82.3 Flaccid tetraplegia	0.002	0.998	0.000
I25.6 Silent myocardial ischaemia	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.998	0.000
C05.8 Overlapping lesion of palate	0.002	0.998	0.000
C05.2 Uvula	0.002	0.998	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.998	0.002
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.002	0.998	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.998	0.002
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
C13.9 Hypopharynx, unspecified	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.002	0.998	0.000
Z95.5 Presence of coronary angioplasty implant and graft	0.000	0.998	0.002
F84 Pervasive developmental disorders	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.002	0.998	0.000
C09.8 Overlapping lesion of tonsil	0.002	0.998	0.000
C09.0 Tonsillar fossa	0.002	0.998	0.000
I23.8 Other current complications following acute myocardial infarction	0.000	0.998	0.002
E56.1 Deficiency of vitamin K	0.002	0.998	0.000
I24.1 Dressler's syndrome	0.000	0.998	0.002
C05.9 Palate, unspecified	0.002	0.998	0.000
X78.0 Home	0.002	0.998	0.000
M62.65 Muscle strain (Pelvic region and thigh)	0.000	0.998	0.002
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand	0.002	0.998	0.000
E04.0 Non-toxic diffuse goitre	0.000	0.998	0.002
M81.0 Postmenopausal osteoporosis	0.002	0.998	0.000
C09.1 Tonsillar pillar (anterior) (posterior)	0.002	0.998	0.000
S81.9 Open wound of lower leg, part unspecified	0.002	0.998	0.000
D05 Carcinoma in situ of breast	0.002	0.998	0.000
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.998	0.002
E56 Other vitamin deficiencies	0.002	0.998	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
M81.6 Localised osteoporosis [Lequesne]	0.002	0.998	0.000
M81.5 Idiopathic osteoporosis	0.002	0.998	0.000
M81.1 Postoophorectomy osteoporosis	0.002	0.998	0.000
D05.7 Other carcinoma in situ of breast	0.002	0.998	0.000
E61.1 Iron deficiency	0.002	0.998	0.000
E04 Other non-toxic goitre	0.000	0.998	0.002
E50-E64 Other nutritional deficiencies	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations