TreeWAS – Variant ID: rs12023396

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I46.0 Cardiac arrest with successful resuscitation	0.000	0.986	0.014
L57.0 Actinic keratosis	0.000	0.987	0.013
G63.2 Diabetic polyneuropathy	0.000	0.990	0.010
D04.3 Skin of other and unspecified parts of face	0.000	0.992	0.008
I46 Cardiac arrest	0.000	0.992	0.008
I46.9 Cardiac arrest, unspecified	0.000	0.993	0.007
D04 Carcinoma in situ of skin	0.000	0.994	0.006
C43.7 Malignant melanoma of lower limb, including hip	0.006	0.994	0.000
I46.1 Sudden cardiac death, so described	0.000	0.994	0.006
D04.5 Skin of trunk	0.000	0.994	0.006
D04.6 Skin of upper limb, including shoulder	0.000	0.994	0.006
D04.7 Skin of lower limb, including hip	0.000	0.994	0.006
G63 Polyneuropathy in diseases classified elsewhere	0.000	0.995	0.005
Z41.1 Other plastic surgery for unacceptable cosmetic appearance	0.005	0.995	0.000
R87.6 Abnormal cytological findings	0.000	0.995	0.005
O21.0 Mild hyperemesis gravidarum	0.005	0.995	0.000
O21 Excessive vomiting in pregnancy	0.005	0.995	0.000
D03.7 Melanoma in situ of lower limb, including hip	0.005	0.995	0.000
D04.4 Skin of scalp and neck	0.000	0.995	0.005
L57 Skin changes due to chronic exposure to nonionising radiation	0.000	0.995	0.005
D04.1 Skin of eyelid, including canthus	0.000	0.995	0.005
O21.9 Vomiting of pregnancy, unspecified	0.005	0.995	0.000
D04.8 Skin of other sites	0.000	0.995	0.005
D04.0 Skin of lip	0.000	0.995	0.005
O21.2 Late vomiting of pregnancy	0.005	0.995	0.000
O21.1 Hyperemesis gravidarum with metabolic disturbance	0.004	0.995	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.996	0.004
D68 Other coagulation defects	0.004	0.996	0.000
D68.8 Other specified coagulation defects	0.004	0.996	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.000	0.996	0.004
G63.6 Polyneuropathy in other musculoskeletal disorders	0.000	0.996	0.004
G63.5 Polyneuropathy in systemic connective tissue disorders	0.000	0.996	0.004
G63.4 Polyneuropathy in nutritional deficiency	0.000	0.996	0.004
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.000	0.996	0.004
G63.1 Polyneuropathy in neoplastic disease	0.000	0.996	0.004
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.000	0.996	0.004
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.000	0.996	0.004
D66 Hereditary factor VIII deficiency	0.004	0.996	0.000
D68.1 Hereditary factor XI deficiency	0.004	0.996	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.004	0.996	0.000
D04.9 Skin, unspecified	0.000	0.996	0.004
D68.9 Coagulation defect, unspecified	0.004	0.996	0.000
D68.2 Hereditary deficiency of other clotting factors	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
D68.5 Primary Thrombophilia	0.004	0.996	0.000
L57.5 Actinic granuloma	0.000	0.996	0.004
L57.3 Poikiloderma of Civatte	0.000	0.996	0.004
L57.2 Cutis rhomboidalis nuchae	0.000	0.996	0.004
L57.1 Actinic reticuloid	0.000	0.996	0.004
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.996	0.004
S81.0 Open wound of knee	0.000	0.996	0.004
O21.8 Other vomiting complicating pregnancy	0.004	0.996	0.000
L57.4 Cutis laxa senilis	0.000	0.996	0.004
M47.86 Other spondylosis (Lumbar region)	0.004	0.996	0.000
D68.6 Other Thrombophilia	0.003	0.996	0.000
H00.0 Hordeolum and other deep inflammation of eyelid	0.003	0.997	0.000
D68.4 Acquired coagulation factor deficiency	0.003	0.997	0.000
M34.9 Systemic sclerosis, unspecified	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.003	0.997	0.000
M47.8 Other spondylosis	0.003	0.997	0.000
Z41 Procedures for purposes other than remedying health state	0.003	0.997	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.997	0.003
O26 Maternal care for other conditions predominantly related to pregnancy	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
O26.7 Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium	0.003	0.997	0.000
T51.0 Ethanol	0.000	0.997	0.003
E83.1 Disorders of iron metabolism	0.000	0.997	0.003
N87.0 Mild cervical dysplasia	0.000	0.997	0.003
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
Z46.6 Fitting and adjustment of urinary device	0.000	0.997	0.003
M47.84 Other spondylosis (Thoracic region)	0.003	0.997	0.000
G83.4 Cauda equina syndrome	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.997	0.003
O23.5 Infections of the genital tract in pregnancy	0.003	0.997	0.000
T31.0 Burns involving less than 10% of body surface	0.003	0.997	0.000
O26.8 Other specified pregnancy-related conditions	0.003	0.997	0.000
Z41.8 Other procedures for purposes other than remedying health state	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
O23 Infections of genito-urinary tract in pregnancy	0.003	0.997	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.003	0.997	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.003	0.997	0.000
O26.3 Retained intra-uterine contraceptive device in pregnancy	0.003	0.997	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.003	0.997	0.000
D68.0 Von Willebrand's disease	0.003	0.997	0.000
Z41.2 Routine and ritual circumcision	0.003	0.997	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.003	0.997	0.000
D67 Hereditary factor IX deficiency	0.003	0.997	0.000
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.002	0.997	0.000
O26.0 Excessive weight gain in pregnancy	0.003	0.997	0.000
D03.4 Melanoma in situ of scalp and neck	0.003	0.997	0.000
L29.0 Pruritus ani	0.000	0.997	0.003
Z41.9 Procedures for purposes other than remedying health state, unspecified	0.002	0.997	0.000
Z41.3 Ear piercing	0.002	0.997	0.000
Z41.0 Hair transplant	0.002	0.997	0.000
D03 Melanoma in situ	0.003	0.997	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.997	0.002
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.997	0.002
O26.5 Maternal hypotension syndrome	0.002	0.997	0.000
O26.4 Herpes gestationis	0.002	0.997	0.000
O26.1 Low weight gain in pregnancy	0.002	0.997	0.000
C43.4 Malignant melanoma of scalp and neck	0.003	0.997	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.997	0.000
O26.9 Pregnancy-related condition, unspecified	0.003	0.997	0.000
O26.6 Liver disorders in pregnancy, childbirth and the puerperium	0.002	0.997	0.000
N87.9 Dysplasia of cervix uteri, unspecified	0.000	0.997	0.003
O20.0 Threatened abortion	0.003	0.997	0.000
T51 Toxic effect of alcohol	0.000	0.997	0.003
M47.85 Other spondylosis (Thoracolumbar region)	0.002	0.997	0.000
M34 Systemic sclerosis	0.002	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.998	0.002
M34.1 CR(E)ST syndrome	0.002	0.998	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.998	0.002
M84 Disorders of continuity of bone	0.000	0.998	0.002
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.002	0.998	0.000
O29 Complications of anaesthesia during pregnancy	0.002	0.998	0.000
O25 Malnutrition in pregnancy	0.002	0.998	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.998	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
M84.01 Malunion of fracture (Shoulder region)	0.000	0.998	0.002
M34.8 Other forms of systemic sclerosis	0.002	0.998	0.000
R74.8 Abnormal levels of other serum enzymes	0.000	0.998	0.002
O23.3 Infections of other parts of urinary tract in pregnancy	0.002	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.002	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.002	0.998	0.000
O23.0 Infections of kidney in pregnancy	0.002	0.998	0.000
T51.9 Alcohol, unspecified	0.000	0.998	0.002
X23.9 Unspecified place	0.000	0.998	0.002
M84.0 Malunion of fracture	0.000	0.998	0.002
S60.9 Superficial injury of wrist and hand, unspecified	0.000	0.998	0.002
T63.4 Venom of other arthropods	0.000	0.998	0.002
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.998	0.002
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.998	0.002
C43.9 Malignant melanoma of skin, unspecified	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
C43 Malignant melanoma of skin	0.002	0.998	0.000
D69.5 Secondary thrombocytopenia	0.002	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.000	0.998	0.002
L89.1 Stage II decubitus ulcer	0.000	0.998	0.002
N87.2 Severe cervical dysplasia, not elsewhere classified	0.000	0.998	0.002
S81 Open wound of lower leg	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.000	0.998	0.002
M84.03 Malunion of fracture (Forearm)	0.000	0.998	0.002
D03.6 Melanoma in situ of upper limb, including shoulder	0.002	0.998	0.000
M84.04 Malunion of fracture (Hand)	0.000	0.998	0.002
D03.9 Melanoma in situ, unspecified	0.002	0.998	0.000
D03.8 Melanoma in situ of other sites	0.002	0.998	0.000
D03.2 Melanoma in situ of ear and external auricular canal	0.002	0.998	0.000
D03.1 Melanoma in situ of eyelid, including canthus	0.002	0.998	0.000
D03.0 Melanoma in situ of lip	0.002	0.998	0.000
M34.0 Progressive systemic sclerosis	0.002	0.998	0.000
M84.8 Other disorders of continuity of bone	0.000	0.998	0.002
N87 Dysplasia of cervix uteri	0.000	0.998	0.002
N48.6 Balanitis xerotica obliterans	0.000	0.998	0.002
T51.8 Other alcohols	0.000	0.998	0.002
T51.3 Fusel oil	0.000	0.998	0.002
T51.2 2-Propanol	0.000	0.998	0.002
T51.1 Methanol	0.000	0.998	0.002
M34.2 Systemic sclerosis induced by drugs and chemicals	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
Z47.8 Other specified orthopaedic follow-up care	0.000	0.998	0.002
M84.9 Disorder of continuity of bone, unspecified	0.000	0.998	0.002
M84.3 Stress fracture, not elsewhere classified	0.000	0.998	0.002
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
O26.2 Pregnancy care of habitual aborter	0.002	0.998	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.002	0.998	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.6 Failed or difficult intubation during pregnancy	0.002	0.998	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.002	0.998	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.002	0.998	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.002	0.998	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.002	0.998	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
O22 Venous complications in pregnancy	0.002	0.998	0.000
T63 Toxic effect of contact with venomous animals	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.998	0.002
M84.2 Delayed union of fracture	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.000	0.998	0.002
M84.08 Malunion of fracture (Other)	0.000	0.998	0.002
M84.00 Malunion of fracture (Multiple sites)	0.000	0.998	0.002
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.000	0.998	0.002
C43.8 Overlapping malignant melanoma of skin	0.002	0.998	0.000
C43.0 Malignant melanoma of lip	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.000	0.998	0.002
C43.3 Malignant melanoma of other and unspecified parts of face	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.000	0.998	0.002
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
C43.2 Malignant melanoma of ear and external auricular canal	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
I12.9 Hypertensive renal disease without renal failure	0.000	0.998	0.002
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.998	0.002
G44.2 Tension-type headache	0.000	0.998	0.002
S51.8 Open wound of other parts of forearm	0.000	0.998	0.002
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.998	0.002
S32.0 Fracture of lumbar vertebra	0.000	0.998	0.002
Z03.1 Observation for suspected malignant neoplasm	0.000	0.998	0.002
T90.9 Sequelae of unspecified injury of head	0.000	0.998	0.002
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.998	0.002
M84.88 Other disorders of continuity of bone (Other)	0.000	0.998	0.002
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.998	0.002
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.998	0.002
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.998	0.002
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.998	0.002
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.998	0.002
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.998	0.002
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.998	0.002
R87 Abnormal findings in specimens from female genital organs	0.000	0.998	0.002
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.998	0.002
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.998	0.002
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.998	0.001
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.001
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.001
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.998	0.001
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.998	0.001
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.001
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.998	0.001
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.998	0.001
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.998	0.001
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.998	0.001
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.998	0.001
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.998	0.001
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.998	0.001
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.998	0.001
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.998	0.001
C43.1 Malignant melanoma of eyelid, including canthus	0.002	0.998	0.000
G60.8 Other hereditary and idiopathic neuropathies	0.000	0.998	0.002
G04 Encephalitis, myelitis and encephalomyelitis	0.002	0.998	0.000
G60 Hereditary and idiopathic neuropathy	0.000	0.998	0.002
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
O22.9 Venous complication in pregnancy, unspecified	0.001	0.998	0.000
O22.8 Other venous complications in pregnancy	0.001	0.998	0.000
O22.5 Cerebral venous thrombosis in pregnancy	0.001	0.998	0.000
O22.3 Deep phlebothrombosis in pregnancy	0.001	0.998	0.000
O22.2 Superficial thrombophlebitis in pregnancy	0.001	0.998	0.000
O22.1 Genital varices in pregnancy	0.001	0.998	0.000
T63.9 Toxic effect of contact with unspecified venomous animal	0.000	0.998	0.002
T63.8 Toxic effect of contact with other venomous animals	0.000	0.998	0.002
T63.6 Toxic effect of contact with other marine animals	0.000	0.998	0.002
T63.5 Toxic effect of contact with fish	0.000	0.998	0.002
T63.3 Venom of spider	0.000	0.998	0.002
T63.2 Venom of scorpion	0.000	0.998	0.002
T63.1 Venom of other reptiles	0.000	0.998	0.002
T63.0 Snake venom	0.000	0.998	0.002
D03.3 Melanoma in situ of other and unspecified parts of face	0.002	0.998	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.998	0.001
M84.28 Delayed union of fracture (Other)	0.000	0.998	0.001
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.998	0.001
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.998	0.001
M84.24 Delayed union of fracture (Hand)	0.000	0.998	0.001
M84.23 Delayed union of fracture (Forearm)	0.000	0.998	0.001
M84.22 Delayed union of fracture (Upper arm)	0.000	0.998	0.001
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.998	0.001
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.998	0.001
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.998	0.002
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.998	0.001
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.998	0.001
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.998	0.001
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.998	0.001
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.998	0.001
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
L81.4 Other melanin hyperpigmentation	0.000	0.998	0.002
T31 Burns classified according to extent of body surface involved	0.002	0.998	0.000
D69.2 Other nonthrombocytopenic purpura	0.002	0.998	0.000
Z03.6 Observation for suspected toxic effect from ingested substance	0.000	0.998	0.002
G64 Other disorders of peripheral nervous system	0.000	0.998	0.002
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.998	0.001
M81.28 Osteoporosis of disuse (Other)	0.000	0.998	0.001
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.998	0.001
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.998	0.001
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.998	0.001
M81.24 Osteoporosis of disuse (Hand)	0.000	0.998	0.001
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.998	0.001
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.998	0.001
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.998	0.001
M84.06 Malunion of fracture (Lower leg)	0.000	0.998	0.001
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.000	0.998	0.002
O20.8 Other haemorrhage in early pregnancy	0.001	0.998	0.000
L58 Radiodermatitis	0.000	0.998	0.001
L55 Sunburn	0.000	0.998	0.001
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.001
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.001
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.001
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.001
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.001
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.001
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.001
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.001
A08.1 Acute gastro-enteropathy due to Norwalk agent	0.000	0.998	0.002
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.998	0.002
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.001
D69.4 Other primary thrombocytopenia	0.002	0.998	0.000
O22.0 Varicose veins of lower extremity in pregnancy	0.001	0.998	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.998	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.998	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.998	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.998	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.998	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.998	0.000
T65 Toxic effect of other and unspecified substances	0.000	0.998	0.002
L56 Other acute skin changes due to ultraviolet radiation	0.000	0.998	0.001
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
M84.26 Delayed union of fracture (Lower leg)	0.000	0.998	0.001
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.998	0.001
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.001
S92.00 Fracture of calcaneus (closed)	0.000	0.998	0.002
D69.8 Other specified haemorrhagic conditions	0.001	0.998	0.000
D69.1 Qualitative platelet defects	0.001	0.998	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.002	0.998	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
W29.9 Unspecified place	0.000	0.998	0.002
R21 Rash and other nonspecific skin eruption	0.002	0.998	0.000
T58 Toxic effect of carbon monoxide	0.000	0.998	0.002
R87.8 Other abnormal findings	0.000	0.998	0.001
R87.5 Abnormal microbiological findings	0.000	0.998	0.001
R87.4 Abnormal immunological findings	0.000	0.998	0.001
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.998	0.001
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.998	0.001
R87.1 Abnormal level of hormones	0.000	0.998	0.001
R87.0 Abnormal level of enzymes	0.000	0.998	0.001
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.998	0.001
S60.0 Contusion of finger(s) without damage to nail	0.000	0.998	0.001
T65.9 Toxic effect of unspecified substance	0.000	0.998	0.001
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.000	0.998	0.001
O24 Diabetes mellitus in pregnancy	0.001	0.998	0.000
X23 Contact with hornets, wasps and bees	0.000	0.998	0.001
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.998	0.001
R87.9 Unspecified abnormal finding	0.000	0.998	0.001
T61 Toxic effect of noxious substances eaten as seafood	0.000	0.998	0.001
T60 Toxic effect of pesticides	0.000	0.998	0.001
T57 Toxic effect of other inorganic substances	0.000	0.998	0.001
T54 Toxic effect of corrosive substances	0.000	0.998	0.001
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.000	0.998	0.001
T52 Toxic effect of organic solvents	0.000	0.998	0.001
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.000	0.998	0.001
T55 Toxic effect of soaps and detergents	0.000	0.998	0.001
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.001	0.998	0.000
G04.1 Tropical spastic paraplegia	0.001	0.998	0.000
G04.0 Acute disseminated encephalitis	0.001	0.998	0.000
G60.3 Idiopathic progressive neuropathy	0.000	0.998	0.001
G60.2 Neuropathy in association with hereditary ataxia	0.000	0.998	0.001
G60.1 Refsum's disease	0.000	0.998	0.001
G82.5 Tetraplegia, unspecified	0.000	0.998	0.001
S32.3 Fracture of ilium	0.000	0.998	0.001
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.001
G62 Other polyneuropathies	0.000	0.998	0.001
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.001	0.999	0.000
G96.0 Cerebrospinal fluid leak	0.001	0.999	0.000
O22.4 Haemorrhoids in pregnancy	0.001	0.999	0.001
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.999	0.000
T31.9 Burns involving 90% or more of body surface	0.001	0.999	0.000
T31.8 Burns involving 80-89% of body surface	0.001	0.999	0.000
T31.7 Burns involving 70-79% of body surface	0.001	0.999	0.000
T31.6 Burns involving 60-69% of body surface	0.001	0.999	0.000
T31.5 Burns involving 50-59% of body surface	0.001	0.999	0.000
T31.4 Burns involving 40-49% of body surface	0.001	0.999	0.000
T31.3 Burns involving 30-39% of body surface	0.001	0.999	0.000
T31.2 Burns involving 20-29% of body surface	0.001	0.999	0.000
T56 Toxic effect of metals	0.000	0.999	0.001
C48.2 Peritoneum, unspecified	0.000	0.999	0.001
L55.9 Sunburn, unspecified	0.000	0.999	0.001
L55.8 Other sunburn	0.000	0.999	0.001
L55.2 Sunburn of third degree	0.000	0.999	0.001
L55.1 Sunburn of second degree	0.000	0.999	0.001
L55.0 Sunburn of first degree	0.000	0.999	0.001
L58.9 Radiodermatitis, unspecified	0.000	0.999	0.001
L58.1 Chronic radiodermatitis	0.000	0.999	0.001
L58.0 Acute radiodermatitis	0.000	0.999	0.001
X23.0 Home	0.000	0.999	0.001
Z03.3 Observation for suspected nervous system disorder	0.000	0.999	0.001
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.001	0.999	0.000
A40.3 Septicaemia due to Streptococcus pneumoniae	0.000	0.999	0.001
D69.0 Allergic purpura	0.001	0.999	0.000
M81.0 Postmenopausal osteoporosis	0.000	0.999	0.001
M80-M85 Disorders of bone density and structure	0.000	0.999	0.001
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.999	0.001
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.000	0.999	0.001
M85.6 Other cyst of bone	0.000	0.999	0.001
T31.1 Burns involving 10-19% of body surface	0.001	0.999	0.000
T65.8 Toxic effect of other specified substances	0.000	0.999	0.001
T65.6 Paints and dyes, not elsewhere classified	0.000	0.999	0.001
T65.5 Nitroglycerin and other nitric acids and esters	0.000	0.999	0.001
T65.4 Carbon disulphide	0.000	0.999	0.001
T65.3 Nitroderivatives and aminoderivatives of benzene and its homologues	0.000	0.999	0.001
T65.2 Tobacco and nicotine	0.000	0.999	0.001
T65.1 Strychnine and its salts	0.000	0.999	0.001
T65.0 Cyanides	0.000	0.999	0.001
T59 Toxic effect of other gases, fumes and vapours	0.000	0.999	0.001
C49.2 Connective and soft tissue of lower limb, including hip	0.000	0.999	0.001
D69.9 Haemorrhagic condition, unspecified	0.001	0.999	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.000	0.999	0.001
G62.0 Drug-induced polyneuropathy	0.000	0.999	0.001
L56.4 Polymorphous light eruption	0.000	0.999	0.001
L56.3 Solar urticaria	0.000	0.999	0.001
L56.2 Photocontact dermatitis [berloque dermatitis]	0.000	0.999	0.001
L56.1 Drug photoallergic response	0.000	0.999	0.001
L56.0 Drug phototoxic response	0.000	0.999	0.001
M81.8 Other osteoporosis	0.000	0.999	0.001
M81.6 Localised osteoporosis [Lequesne]	0.000	0.999	0.001
M81.5 Idiopathic osteoporosis	0.000	0.999	0.001
M81.1 Postoophorectomy osteoporosis	0.000	0.999	0.001
Z57.2 Occupational exposure to dust	0.000	0.999	0.001
T62 Toxic effect of other noxious substances eaten as food	0.000	0.999	0.001
J45.0 Predominantly allergic asthma	0.001	0.999	0.000
G60.0 Hereditary motor and sensory neuropathy	0.000	0.999	0.001
G62.9 Polyneuropathy, unspecified	0.000	0.999	0.001
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.000	0.999	0.001
L59.0 Erythema ab igne [dermatitis ab igne]	0.000	0.999	0.001
S79.9 Unspecified injury of hip and thigh	0.000	0.999	0.001
X23.8 Other specified place	0.000	0.999	0.001
X23.7 Farm	0.000	0.999	0.001
X23.6 Industrial and construction area	0.000	0.999	0.001
X23.5 Trade and service area	0.000	0.999	0.001
X23.4 Street and highway	0.000	0.999	0.001
X23.3 Sports and athletics area	0.000	0.999	0.001
X23.2 School, other institution and public administrative area	0.000	0.999	0.001
X23.1 Residential institution	0.000	0.999	0.001
X59.3 Sports and athletics area	0.000	0.999	0.001
Z40.8 Other prophylactic surgery	0.000	0.999	0.001
S32.31 Fracture of ilium (open)	0.000	0.999	0.001
N08.3 Glomerular disorders in diabetes mellitus	0.000	0.999	0.001
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.999	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.999	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.999	0.000
R87.7 Abnormal histological findings	0.001	0.999	0.001
T52.9 Organic solvent, unspecified	0.000	0.999	0.001
T52.8 Other organic solvents	0.000	0.999	0.001
T52.4 Ketones	0.000	0.999	0.001
T52.3 Glycols	0.000	0.999	0.001
T52.2 Homologues of benzene	0.000	0.999	0.001
T52.1 Benzene	0.000	0.999	0.001
T52.0 Petroleum products	0.000	0.999	0.001
T53.9 Halogen derivative of aliphatic and aromatic hydrocarbons, unspecified	0.000	0.999	0.001
T53.7 Other halogen derivatives of aromatic hydrocarbons	0.000	0.999	0.001
T53.6 Other halogen derivatives of aliphatic hydrocarbons	0.000	0.999	0.001
T53.5 Chlorofluorocarbons	0.000	0.999	0.001
T53.4 Dichloromethane	0.000	0.999	0.001
T53.3 Tetrachloroethylene	0.000	0.999	0.001
T53.2 Trichloroethylene	0.000	0.999	0.001
T53.1 Chloroform	0.000	0.999	0.001
T53.0 Carbon tetrachloride	0.000	0.999	0.001
T54.9 Corrosive substance, unspecified	0.000	0.999	0.001
T54.3 Corrosive alkalis and alklali-like substances	0.000	0.999	0.001
T54.2 Corrosive acids and acid-like substances	0.000	0.999	0.001
T54.1 Other corrosive organic compounds	0.000	0.999	0.001
T54.0 Phenol and phenol homologues	0.000	0.999	0.001
T57.9 Inorganic substance, unspecified	0.000	0.999	0.001
T57.8 Other specified inorganic substances	0.000	0.999	0.001
T57.3 Hydrogen cyanide	0.000	0.999	0.001
T57.2 Manganese and its compounds	0.000	0.999	0.001
T57.1 Phosphorus and its compounds	0.000	0.999	0.001
T57.0 Arsenic and its compounds	0.000	0.999	0.001
T60.9 Pesticide, unspecified	0.000	0.999	0.001
T60.8 Other pesticides	0.000	0.999	0.001
T60.4 Rodenticides	0.000	0.999	0.001
T60.3 Herbicides and fungicides	0.000	0.999	0.001
T60.2 Other insecticides	0.000	0.999	0.001
T60.1 Halogenated insecticides	0.000	0.999	0.001
T60.0 Organophosphate and carbamate insecticides	0.000	0.999	0.001
T61.9 Toxic effect of unspecified seafood	0.000	0.999	0.001
T61.8 Toxic effect of other seafoods	0.000	0.999	0.001
T61.2 Other fish and shellfish poisoning	0.000	0.999	0.001
T61.1 Scombroid fish poisoning	0.000	0.999	0.001
T61.0 Ciguatera fish poisoning	0.000	0.999	0.001
Z80.8 Family history of malignant neoplasm of other organs or systems	0.000	0.999	0.001
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.999	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.999	0.001
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.999	0.001
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation	0.000	0.999	0.001
S60 Superficial injury of wrist and hand	0.000	0.999	0.001
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.999	0.001
M85.64 Other cyst of bone (Hand)	0.000	0.999	0.001
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.999	0.001
G00.1 Pneumococcal meningitis	0.001	0.999	0.000
G62.2 Polyneuropathy due to other toxic agents	0.000	0.999	0.001
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.000	0.999	0.001
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations