TreeWAS – Variant ID: rs12027135

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O36.0 Maternal care for rhesus isoimmunisation	1.000	0.000	0.000
Z29.1 Prophylactic immunotherapy	0.952	0.048	0.000
Z29 Need for other prophylactic measures	0.176	0.824	0.000
Z29.9 Prophylactic measure, unspecified	0.126	0.873	0.000
Z29.2 Other prophylactic chemotherapy	0.107	0.893	0.000
Z29.0 Isolation	0.092	0.908	0.000
Z29.8 Other specified prophylactic measures	0.079	0.921	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.055	0.945	0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.045	0.955	0.000
M79.62 Pain in limb (Upper arm)	0.000	0.958	0.042
Z20 Contact with and exposure to communicable diseases	0.041	0.959	0.000
Z28 Immunisation not carried out	0.040	0.960	0.000
Z27 Need for immunisation against combinations of infectious diseases	0.040	0.960	0.000
Z25 Need for immunisation against other single viral diseases	0.040	0.960	0.000
Z23 Need for immunisation against single bacterial diseases	0.040	0.960	0.000
Z26 Need for immunisation against other single infectious diseases	0.039	0.960	0.000
G57.6 Lesion of plantar nerve	0.040	0.960	0.000
Z24 Need for immunisation against certain single viral diseases	0.037	0.963	0.000
Z20.9 Contact with and exposure to unspecified communicable disease	0.032	0.968	0.000
Z20.1 Contact with and exposure to tuberculosis	0.031	0.969	0.000
Z20.7 Contact with and exposure to pediculosis, acariasis and other infestations	0.030	0.970	0.000
Z20.6 Contact with and exposure to human immunodeficiency virus [HIV]	0.030	0.970	0.000
Z20.5 Contact with and exposure to viral hepatitis	0.030	0.970	0.000
Z20.4 Contact with and exposure to rubella	0.030	0.970	0.000
Z20.3 Contact with and exposure to rabies	0.030	0.970	0.000
Z20.2 Contact with and exposure to infections with a predominantly sexual mode of transmission	0.030	0.970	0.000
Z20.0 Contact with and exposure to intestinal infectious diseases	0.030	0.970	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.029	0.971	0.000
Z23.7 Need for immunisation against pertussis alone	0.029	0.971	0.000
Z23.6 Need for immunisation against diphtheria alone	0.029	0.971	0.000
Z23.5 Need for immunisation against tetanus alone	0.029	0.971	0.000
Z23.4 Need for immunisation against tularaemia	0.029	0.971	0.000
Z23.3 Need for immunisation against plague	0.029	0.971	0.000
Z23.2 Need for immunisation against tuberculosis [BCG]	0.029	0.971	0.000
Z23.1 Need for immunisation against typhoid-paratyphoid alone [TAB]	0.029	0.971	0.000
Z23.0 Need for immunisation against cholera alone	0.029	0.971	0.000
Z25.8 Need for immunisation against other specified single viral diseases	0.029	0.971	0.000
Z25.1 Need for immunisation against influenza	0.029	0.971	0.000
Z25.0 Need for immunisation against mumps alone	0.029	0.971	0.000
Z27.9 Need for immunisation against unspecified combinations of infectious diseases	0.029	0.971	0.000
Z27.8 Need for immunisation against other combinations of infectious diseases	0.029	0.971	0.000
Z27.4 Need for immunisation against measles-mumps-rubella [MMR]	0.029	0.971	0.000
Z27.3 Need for immunisation against diphtheria-tetanus-pertussis with poliomyelitis [DTP + polio]	0.029	0.971	0.000
Z27.2 Need for immunisation against diphtheria-tetanus-pertussis with typhoid-paratyphoid [DTP + TAB]	0.029	0.971	0.000
Z27.1 Need for immunisation against diphtheria-tetanus-pertussis, combined [DTP]	0.029	0.971	0.000
Z27.0 Need for immunisation against cholera with typhoid-paratyphoid [cholera + TAB]	0.029	0.971	0.000
Z28.9 Immunisation not carried out for unspecified reason	0.029	0.971	0.000
Z28.8 Immunisation not carried out for other reasons	0.029	0.971	0.000
Z28.2 Immunisation not carried out because of patient's decision for other and unspecified reasons	0.029	0.971	0.000
Z28.1 Immunisation not carried out because of patient's decision for reasons of belief or group pressure	0.029	0.971	0.000
Z28.0 Immunisation not carried out because of contraindication	0.029	0.971	0.000
Z26.8 Need for immunisation against other specified single infectious diseases	0.028	0.971	0.000
Z26.0 Need for immunisation against leishmaniasis	0.028	0.971	0.000
Z26.9 Need for immunisation against unspecified infectious disease	0.028	0.972	0.000
Z24.6 Need for immunisation against viral hepatitis	0.027	0.973	0.000
Z24.4 Need for immunisation against measles alone	0.027	0.973	0.000
Z24.3 Need for immunisation against yellow fever	0.027	0.973	0.000
Z24.2 Need for immunisation against rabies	0.027	0.973	0.000
Z24.1 Need for immunisation against arthropod-borne viral encephalitis	0.027	0.973	0.000
Z24.0 Need for immunisation against poliomyelitis	0.027	0.973	0.000
Z20.8 Contact with and exposure to other communicable diseases	0.026	0.973	0.000
O36 Maternal care for other known or suspected foetal problems	0.026	0.974	0.000
G57 Mononeuropathies of lower limb	0.025	0.975	0.000
Z24.5 Need for immunisation against rubella alone	0.024	0.976	0.000
G57.5 Tarsal tunnel syndrome	0.022	0.978	0.000
G57.8 Other mononeuropathies of lower limb	0.022	0.978	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.021	0.979	0.000
Z22 Carrier of infectious disease	0.021	0.979	0.000
M25.51 Pain in joint (Shoulder region)	0.000	0.979	0.021
O36.2 Maternal care for hydrops foetalis	0.021	0.979	0.000
O36.5 Maternal care for poor foetal growth	0.020	0.980	0.000
O36.1 Maternal care for other isoimmunisation	0.019	0.981	0.000
G57.9 Mononeuropathy of lower limb, unspecified	0.019	0.981	0.000
G57.0 Lesion of sciatic nerve	0.019	0.981	0.000
O36.4 Maternal care for intra-uterine death	0.018	0.982	0.000
G57.4 Lesion of medial popliteal nerve	0.018	0.982	0.000
G57.2 Lesion of femoral nerve	0.018	0.982	0.000
M25.56 Pain in joint (Lower leg)	0.000	0.983	0.017
Z22.9 Carrier of infectious disease, unspecified	0.015	0.985	0.000
Z22.6 Carrier of human T-lymphotropic virus type 1 [HTLV-1] infection	0.015	0.985	0.000
Z22.4 Carrier of infections with a predominantly sexual mode of transmission	0.015	0.985	0.000
Z22.2 Carrier of diphtheria	0.015	0.985	0.000
Z22.0 Carrier of typhoid	0.015	0.985	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.985	0.015
Z22.5 Carrier of viral hepatitis	0.015	0.985	0.000
M25.5 Pain in joint	0.000	0.985	0.015
I12.0 Hypertensive renal disease with renal failure	0.000	0.986	0.014
C77.1 Intrathoracic lymph nodes	0.000	0.986	0.014
G57.3 Lesion of lateral popliteal nerve	0.014	0.986	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.986	0.014
G57.1 Meralgia paraesthetica	0.013	0.987	0.000
Z22.8 Carrier of other infectious diseases	0.012	0.987	0.000
M25.53 Pain in joint (Forearm)	0.000	0.988	0.012
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.988	0.012
C77.0 Lymph nodes of head, face and neck	0.000	0.988	0.012
Z22.1 Carrier of other intestinal infectious diseases	0.012	0.988	0.000
M25.59 Pain in joint (Site unspecified)	0.000	0.988	0.012
C77.8 Lymph nodes of multiple regions	0.000	0.989	0.011
Z22.3 Carrier of other specified bacterial diseases	0.011	0.989	0.000
M25.54 Pain in joint (Hand)	0.000	0.990	0.010
O36.6 Maternal care for excessive foetal growth	0.009	0.991	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.008	0.991	0.001
M25.58 Pain in joint (Other)	0.000	0.991	0.009
M25.52 Pain in joint (Upper arm)	0.000	0.991	0.008
C80.9 Malignant neoplasm, unspecified	0.000	0.993	0.007
O36.9 Maternal care for foetal problem, unspecified	0.006	0.993	0.001
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.007	0.993	0.000
C80 Malignant neoplasm without specification of site	0.000	0.994	0.006
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.000	0.994	0.006
O32.8 Maternal care for other malpresentation of foetus	0.006	0.994	0.000
I12 Hypertensive renal disease	0.000	0.994	0.006
O32 Maternal care for known or suspected malpresentation of foetus	0.006	0.994	0.000
O32.2 Maternal care for transverse and oblique lie	0.006	0.994	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.994	0.006
O72.0 Third-stage haemorrhage	0.000	0.994	0.006
C77.4 Inguinal and lower limb lymph nodes	0.000	0.995	0.005
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.995	0.005
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.995	0.005
C77.9 Lymph node, unspecified	0.000	0.995	0.005
O32.1 Maternal care for breech presentation	0.005	0.995	0.000
O32.4 Maternal care for high head at term	0.005	0.995	0.000
O32.3 Maternal care for face, brow and chin presentation	0.005	0.995	0.000
O32.9 Maternal care for malpresentation of foetus, unspecified	0.005	0.995	0.000
M11.26 Other chondrocalcinosis (Lower leg)	0.000	0.995	0.005
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.005	0.995	0.000
C76 Malignant neoplasm of other and ill-defined sites	0.000	0.995	0.004
M25.50 Pain in joint (Multiple sites)	0.000	0.995	0.004
C79 Secondary malignant neoplasm of other sites	0.000	0.996	0.004
C76.3 Pelvis	0.000	0.996	0.004
I46.0 Cardiac arrest with successful resuscitation	0.004	0.996	0.000
I15.1 Hypertension secondary to other renal disorders	0.000	0.996	0.004
O32.6 Maternal care for compound presentation	0.004	0.996	0.000
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.004	0.996	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.996	0.004
H47.3 Other disorders of optic disk	0.000	0.996	0.004
S50.9 Superficial injury of forearm, unspecified	0.000	0.996	0.004
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.996	0.004
K83.0 Cholangitis	0.004	0.996	0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified	0.000	0.996	0.004
Z51.5 Palliative care	0.000	0.996	0.004
Z58.1 Exposure to air pollution	0.000	0.996	0.004
N49.2 Inflammatory disorders of scrotum	0.000	0.996	0.004
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.000	0.996	0.004
C76.1 Thorax	0.000	0.996	0.003
C76.8 Overlapping lesion of other and ill-defined sites	0.000	0.996	0.003
C76.7 Other ill-defined sites	0.000	0.996	0.003
C76.5 Lower limb	0.000	0.996	0.003
C76.4 Upper limb	0.000	0.996	0.003
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.996	0.000
N20.2 Calculus of kidney with calculus of ureter	0.003	0.997	0.000
C92.0 Acute myeloid leukaemia	0.003	0.997	0.000
O32.0 Maternal care for unstable lie	0.003	0.997	0.000
K29.0 Acute haemorrhagic gastritis	0.000	0.997	0.003
Z08 Follow-up examination after treatment for malignant neoplasm	0.003	0.997	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.997	0.003
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.997	0.003
I15 Secondary hypertension	0.000	0.997	0.003
C76.0 Head, face and neck	0.000	0.997	0.003
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.997	0.003
S50 Superficial injury of forearm	0.000	0.997	0.003
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.003	0.997	0.000
E22.1 Hyperprolactinaemia	0.000	0.997	0.003
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.003	0.997	0.000
N18.9 Chronic renal failure, unspecified	0.000	0.997	0.003
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.003	0.997	0.000
E22 Hyperfunction of pituitary gland	0.000	0.997	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.003	0.997	0.000
S50.1 Contusion of other and unspecified parts of forearm	0.000	0.997	0.003
C76.2 Abdomen	0.000	0.997	0.003
S50.7 Multiple superficial injuries of forearm	0.000	0.997	0.003
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.003	0.997	0.000
O46.8 Other antepartum haemorrhage	0.003	0.997	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.003	0.997	0.000
I10-I15 Hypertensive diseases	0.000	0.997	0.003
I12.9 Hypertensive renal disease without renal failure	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
S50.0 Contusion of elbow	0.000	0.997	0.003
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.997	0.003
D86.9 Sarcoidosis, unspecified	0.003	0.997	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.997	0.003
M24.8 Other specific joint derangements, not elsewhere classified	0.003	0.997	0.000
I15.2 Hypertension secondary to endocrine disorders	0.000	0.997	0.002
S50.8 Other superficial injuries of forearm	0.000	0.997	0.003
I15.9 Seconday hypertension, unspecified	0.000	0.997	0.002
I46 Cardiac arrest	0.003	0.997	0.000
O31 Complications specific to multiple gestation	0.002	0.997	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.002	0.997	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.002	0.997	0.000
Z90.0 Acquired absence of part of head and neck	0.002	0.998	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.002	0.998	0.000
O33 Maternal care for known or suspected disproportion	0.002	0.998	0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
I46.9 Cardiac arrest, unspecified	0.002	0.998	0.000
O45 Premature separation of placenta [abruptio placentae]	0.002	0.998	0.000
H47.1 Papilloedema, unspecified	0.000	0.998	0.002
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.998	0.002
E22.8 Other hyperfunction of pituitary gland	0.000	0.998	0.002
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.002	0.998	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.002	0.998	0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.002	0.998	0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.002	0.998	0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.002	0.998	0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.002	0.998	0.000
I15.0 Renovascular hypertension	0.000	0.998	0.002
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.998	0.002
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.998	0.002
I13 Hypertensive heart and renal disease	0.000	0.998	0.002
M25.57 Pain in joint (Ankle and foot)	0.000	0.998	0.002
M11.2 Other chondrocalcinosis	0.000	0.998	0.002
I11 Hypertensive heart disease	0.000	0.998	0.002
I15.8 Other secondary hypertension	0.000	0.998	0.002
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
H47.5 Disorders of other visual pathways	0.000	0.998	0.002
O31.8 Other complications specific to multiple gestation	0.002	0.998	0.000
S14.3 Injury of brachial plexus	0.000	0.998	0.002
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.000	0.998	0.002
H47.7 Disorder of visual pathways, unspecified	0.000	0.998	0.002
H47.6 Disorders of visual cortex	0.000	0.998	0.002
H47.4 Disorders of optic chiasm	0.000	0.998	0.002
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.998	0.002
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.998	0.002
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
H47.2 Optic atrophy	0.000	0.998	0.002
K01.0 Embedded teeth	0.000	0.998	0.002
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.998	0.002
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.000	0.998	0.002
O41 Other disorders of amniotic fluid and membranes	0.002	0.998	0.000
O33.9 Maternal care for disproportion, unspecified	0.002	0.998	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.002	0.998	0.000
O31.0 Papyraceous foetus	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
I46.1 Sudden cardiac death, so described	0.002	0.998	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.002	0.998	0.000
O46.0 Antepartum haemorrhage with coagulation defect	0.002	0.998	0.000
S64.0 Injury of ulnar nerve at wrist and hand level	0.002	0.998	0.000
C79.6 Secondary malignant neoplasm of ovary	0.000	0.998	0.002
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.998	0.002
O33.8 Maternal care for disproportion of other origin	0.002	0.998	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.002	0.998	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.002	0.998	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.002	0.998	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.002	0.998	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.002	0.998	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.002	0.998	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.002	0.998	0.000
O44 Placenta praevia	0.002	0.998	0.000
O45.9 Premature separation of placenta, unspecified	0.002	0.998	0.000
O45.8 Other premature separation of placenta	0.002	0.998	0.000
O45.0 Premature separation of placenta with coagulation defect	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.000	0.998	0.002
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.002	0.998	0.000
G24.5 Blepharospasm	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
M11.27 Other chondrocalcinosis (Ankle and foot)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
G25.3 Myoclonus	0.002	0.998	0.000
O36.8 Maternal care for other specified foetal problems	0.002	0.998	0.000
M11.29 Other chondrocalcinosis (Site unspecified)	0.000	0.998	0.002
M11.28 Other chondrocalcinosis (Other)	0.000	0.998	0.002
M11.25 Other chondrocalcinosis (Pelvic region and thigh)	0.000	0.998	0.002
M11.24 Other chondrocalcinosis (Hand)	0.000	0.998	0.002
M11.22 Other chondrocalcinosis (Upper arm)	0.000	0.998	0.002
M11.20 Other chondrocalcinosis (Multiple sites)	0.000	0.998	0.002
F31.0 Bipolar affective disorder, current episode hypomanic	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.998	0.002
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.998	0.002
N97.9 Female infertility, unspecified	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.002	0.998	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.000	0.998	0.002
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.998	0.002
T80.8 Other complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
O23 Infections of genito-urinary tract in pregnancy	0.002	0.998	0.000
O23.9 Other and unspecified genito-urinary tract infection in pregnancy	0.002	0.998	0.000
O20 Haemorrhage in early pregnancy	0.002	0.998	0.000
O23.4 Unspecified infection of urinary tract in pregnancy	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
K83 Other diseases of biliary tract	0.002	0.998	0.000
M11.21 Other chondrocalcinosis (Shoulder region)	0.000	0.998	0.002
N97.1 Female infertility of tubal origin	0.002	0.998	0.000
O34.0 Maternal care for congenital malformation of uterus	0.002	0.998	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.002	0.998	0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.002	0.998	0.000
G80.1 Spastic diplegia	0.002	0.998	0.000
K83.3 Fistula of bile duct	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.002	0.998	0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.998	0.002
E22.0 Acromegaly and pituitary gigantism	0.000	0.998	0.002
O34.4 Maternal care for other abnormalities of cervix	0.002	0.998	0.000
M79.09 Rheumatism, unspecified (Site unspecified)	0.000	0.998	0.002
C79.2 Secondary malignant neoplasm of skin	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
Q54.0 Hypospadias, balanic	0.000	0.998	0.002
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.002	0.998	0.000
O23.5 Infections of the genital tract in pregnancy	0.002	0.998	0.000
S14.6 Injury of other and unspecified nerves of neck	0.000	0.998	0.002
S14.5 Injury of cervical sympathetic nerves	0.000	0.998	0.002
S14.4 Injury of peripheral nerves of neck	0.000	0.998	0.002
S14.2 Injury of nerve root of cervical spine	0.000	0.998	0.002
S14.0 Concussion and oedema of cervical spinal cord	0.000	0.998	0.002
O34.6 Maternal care for abnormality of vagina	0.002	0.998	0.000
D80 Immunodeficiency with predominantly antibody defects	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
H92.1 Otorrhoea	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
Q54.9 Hypospadias, unspecified	0.000	0.998	0.002
M11.23 Other chondrocalcinosis (Forearm)	0.000	0.998	0.001
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
G25.2 Other specified forms of tremor	0.002	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.002	0.998	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.002	0.998	0.000
M67.1 Other contracture of tendon (sheath)	0.000	0.998	0.002
O34.5 Maternal care for other abnormalities of gravid uterus	0.002	0.998	0.000
D84 Other immunodeficiencies	0.002	0.998	0.000
G20 Parkinson's disease	0.002	0.998	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.998	0.002
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
O23.3 Infections of other parts of urinary tract in pregnancy	0.001	0.998	0.000
O23.2 Infections of urethra in pregnancy	0.001	0.998	0.000
O23.1 Infections of bladder in pregnancy	0.001	0.998	0.000
T80.1 Vascular complications following infusion, transfusion and therapeutic injection	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.002	0.998	0.000
G24 Dystonia	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.998	0.001
F84.5 Asperger's syndrome	0.002	0.998	0.000
K83.9 Disease of biliary tract, unspecified	0.002	0.998	0.000
O23.0 Infections of kidney in pregnancy	0.001	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
D84.1 Defects in the complement system	0.001	0.998	0.000
G80.0 Spastic cerebral palsy	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
O30 Multiple gestation	0.001	0.998	0.000
M00.95 Pyogenic arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
C26.0 Intestinal tract, part unspecified	0.000	0.998	0.002
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.001	0.998	0.000
K83.1 Obstruction of bile duct	0.002	0.998	0.000
N64.9 Disorder of breast, unspecified	0.002	0.998	0.000
O41.1 Infection of amniotic sac and membranes	0.001	0.998	0.000
S10.1 Other and unspecified superficial injuries of throat	0.000	0.998	0.001
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
D84.8 Other specified immunodeficiencies	0.001	0.998	0.000
K05.3 Chronic periodontitis	0.000	0.998	0.002
K83.8 Other specified diseases of biliary tract	0.002	0.998	0.000
O21.8 Other vomiting complicating pregnancy	0.001	0.998	0.000
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.002	0.998	0.000
O28 Abnormal findings on antenatal screening of mother	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.001	0.998	0.000
K35.8 Acute appendicitis, other and unspecified	0.000	0.998	0.002
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
D23.5 Skin of trunk	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.001	0.998	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.001	0.998	0.000
G24.8 Other dystonia	0.001	0.998	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.001	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.001	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.001	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.001	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.001	0.998	0.000
G24.0 Drug-induced dystonia	0.001	0.998	0.000
K83.4 Spasm of sphincter of Oddi	0.001	0.998	0.000
K83.2 Perforation of bile duct	0.001	0.998	0.000
N97.8 Female infertility of other origin	0.001	0.998	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.001	0.998	0.000
G80 Infantile cerebral palsy	0.002	0.998	0.000
O24 Diabetes mellitus in pregnancy	0.001	0.998	0.000
O21 Excessive vomiting in pregnancy	0.001	0.998	0.000
G24.9 Dystonia, unspecified	0.001	0.999	0.000
N18.4 Chronic kidney disease, stage 4	0.000	0.999	0.001
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.000	0.999	0.001
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.001	0.999	0.000
G25.1 Drug-induced tremor	0.001	0.999	0.000
N20.1 Calculus of ureter	0.001	0.999	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.001	0.999	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.001	0.999	0.000
O41.0 Oligohydramnios	0.001	0.999	0.000
S10.9 Superficial injury of neck, part unspecified	0.000	0.999	0.001
N97 Female infertility	0.001	0.999	0.000
S10 Superficial injury of neck	0.000	0.999	0.001
M00.91 Pyogenic arthritis, unspecified (Shoulder region)	0.000	0.999	0.001
G24.4 Idiopathic orofacial dystonia	0.001	0.999	0.000
G24.2 Idiopathic nonfamilial dystonia	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.001	0.999	0.000
G25.4 Drug-induced chorea	0.001	0.999	0.000
G80.8 Other infantile cerebral palsy	0.001	0.999	0.000
K83.5 Biliary cyst	0.001	0.999	0.000
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.999	0.001
C73 Malignant neoplasm of thyroid gland	0.000	0.999	0.001
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.001	0.999	0.000
O21.2 Late vomiting of pregnancy	0.001	0.999	0.000
O22.4 Haemorrhoids in pregnancy	0.001	0.999	0.000
T80.2 Infections following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
O43 Placental disorders	0.001	0.999	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
G24.1 Idiopathic familial dystonia	0.001	0.999	0.000
K65.9 Peritonitis, unspecified	0.000	0.999	0.001
O21.0 Mild hyperemesis gravidarum	0.001	0.999	0.000
O30.9 Multiple gestation, unspecified	0.001	0.999	0.000
O30.8 Other multiple gestation	0.001	0.999	0.000
O30.2 Quadruplet pregnancy	0.001	0.999	0.000
O29 Complications of anaesthesia during pregnancy	0.001	0.999	0.000
O25 Malnutrition in pregnancy	0.001	0.999	0.000
Q54 Hypospadias	0.000	0.999	0.001
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.999	0.001
D29.1 Prostate	0.001	0.999	0.000
G25.5 Other chorea	0.001	0.999	0.000
L95.9 Vasculitis limited to skin, unspecified	0.001	0.999	0.000
O28.8 Other abnormal findings on antenatal screening of mother	0.001	0.999	0.000
O28.5 Abnormal chromosomal and genetic finding on antenatal screening of mother	0.001	0.999	0.000
O28.4 Abnormal radiological finding on antenatal screening of mother	0.001	0.999	0.000
O28.2 Abnormal cytological finding on antenatal screening of mother	0.001	0.999	0.000
O28.0 Abnormal haematological finding on antenatal screening of mother	0.001	0.999	0.000
O34.1 Maternal care for tumour of corpus uteri	0.001	0.999	0.000
D81 Combined immunodeficiencies	0.001	0.999	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.000	0.999	0.001
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.001	0.999	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.001	0.999	0.000
M21.0 Valgus deformity, not elsewhere classified	0.001	0.999	0.000
O34.3 Maternal care for cervical incompetence	0.001	0.999	0.000
Z86.1 Personal history of infectious and parasitic diseases	0.001	0.999	0.000
D83 Common variable immunodeficiency	0.001	0.999	0.000
F31 Bipolar affective disorder	0.001	0.999	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.999	0.001
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
G80.4 Ataxic cerebral palsy	0.001	0.999	0.000
G80.3 Dyskinetic cerebral palsy	0.001	0.999	0.000
O24.3 Pre-existing diabetes mellitus, unspecified	0.001	0.999	0.000
O24.2 Pre-existing malnutrition-related diabetes mellitus	0.001	0.999	0.000
O24.1 Pre-existing diabetes mellitus, noninsulin-dependent	0.001	0.999	0.000
O30.1 Triplet pregnancy	0.001	0.999	0.000
O71.7 Obstetric haematoma of pelvis	0.000	0.999	0.001
G20-G26 Extrapyramidal and movement disorders	0.001	0.999	0.000
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.000	0.999	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.001	0.999	0.000
M67.4 Ganglion	0.000	0.999	0.001
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.001	0.999	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.001	0.999	0.000
R09.3 Abnormal sputum	0.000	0.999	0.001
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.001	0.999	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.999	0.001
T45.0 Antiallergic and antiemetic drugs	0.001	0.999	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.001	0.999	0.000
Z93.3 Colostomy status	0.000	0.999	0.001
M67 Other disorders of synovium and tendon	0.000	0.999	0.001
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.999	0.001
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.999	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.999	0.000
N97.3 Female infertility of cervical origin	0.001	0.999	0.000
N97.2 Female infertility of uterine origin	0.001	0.999	0.000
N97.0 Female infertility associated with anovulation	0.001	0.999	0.000
O61.0 Failed medical induction of labour	0.000	0.999	0.001
S10.7 Multiple superficial injuries of neck	0.000	0.999	0.001
S10.0 Contusion of throat	0.000	0.999	0.001
D82 Immunodeficiency associated with other major defects	0.001	0.999	0.000
O40 Polyhydramnios	0.001	0.999	0.000
O43.2 Morbidly adherent placenta	0.001	0.999	0.000
O22 Venous complications in pregnancy	0.001	0.999	0.000
S10-S19 Injuries to the neck	0.000	0.999	0.001
M67.43 Ganglion, wrist	0.000	0.999	0.001
C45.0 Mesothelioma of pleura	0.001	0.999	0.000
O29.9 Complication of anaesthesia during pregnancy, unspecified	0.001	0.999	0.000
O29.8 Other complications of anaesthesia during pregnancy	0.001	0.999	0.000
O29.6 Failed or difficult intubation during pregnancy	0.001	0.999	0.000
O29.5 Other complications of spinal and epidural anaesthesia during pregnancy	0.001	0.999	0.000
O29.4 Spinal and epidural anaesthesia-induced headache during pregnancy	0.001	0.999	0.000
O29.3 Toxic reaction to local anaesthesia during pregnancy	0.001	0.999	0.000
O29.2 Central nervous system complications of anaesthesia during pregnancy	0.001	0.999	0.000
O29.1 Cardiac complications of anaesthesia during pregnancy	0.001	0.999	0.000
O29.0 Pulmonary complications of anaesthesia during pregnancy	0.001	0.999	0.000
Q54.4 Congenital chordee	0.000	0.999	0.001
Q54.3 Hypospadias, perineal	0.000	0.999	0.001
Q54.2 Hypospadias, penoscrotal	0.000	0.999	0.001
T80.6 Other serum reactions	0.000	0.999	0.001
T80.5 Anaphylactic shock due to serum	0.000	0.999	0.001
T80.4 Rh incompatibility reaction	0.000	0.999	0.001
T80.3 ABO incompatibility reaction	0.000	0.999	0.001
T80.0 Air embolism following infusion, transfusion and therapeutic injection	0.000	0.999	0.001
M00.90 Pyogenic arthritis, unspecified (Multiple sites)	0.000	0.999	0.001
M67.47 Ganglion, ankle and foot	0.000	0.999	0.001
C22.1 Intrahepatic bile duct carcinoma	0.001	0.999	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.999	0.000
N36.2 Urethral caruncle	0.001	0.999	0.000
O43.0 Placental transfusion syndromes	0.001	0.999	0.000
Q54.1 Hypospadias, penile	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
S13.5 Sprain and strain of thyroid region	0.000	0.999	0.001
S13.3 Multiple dislocations of neck	0.000	0.999	0.001
S13.2 Dislocation of other and unspecified parts of neck	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations