TreeWAS – Variant ID: rs12029454

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.00 Fracture of patella (closed)	0.083	0.917	0.000
S82.0 Fracture of patella	0.047	0.953	0.000
J38.3 Other diseases of vocal cords	0.000	0.956	0.044
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.000	0.962	0.038
J38.7 Other diseases of larynx	0.000	0.965	0.035
J38.0 Paralysis of vocal cords and larynx	0.000	0.965	0.035
S82.01 Fracture of patella (open)	0.034	0.966	0.000
J38.1 Polyp of vocal cord and larynx	0.000	0.967	0.033
K04.7 Periapical abscess without sinus	0.000	0.969	0.031
J38.6 Stenosis of larynx	0.000	0.972	0.027
J38.5 Laryngeal spasm	0.000	0.974	0.026
J38.4 Oedema of larynx	0.000	0.975	0.025
N50.8 Other specified disorders of male genital organs	0.023	0.977	0.000
J38.2 Nodules of vocal cords	0.000	0.978	0.022
S82 Fracture of lower leg, including ankle	0.021	0.979	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.982	0.018
S82.2 Fracture of shaft of tibia	0.017	0.983	0.000
N86 Erosion and ectropion of cervix uteri	0.017	0.983	0.000
F31.9 Bipolar affective disorder, unspecified	0.017	0.983	0.000
F31 Bipolar affective disorder	0.016	0.984	0.000
S82.20 Fracture of shaft of tibia (closed)	0.016	0.984	0.000
M54.57 Low back pain (Lumbosacral region)	0.016	0.984	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.015	0.984	0.000
S82.3 Fracture of lower end of tibia	0.015	0.985	0.000
S82.7 Multiple fractures of lower leg	0.015	0.985	0.000
S82.9 Fracture of lower leg, part unspecified	0.015	0.985	0.000
S82.4 Fracture of fibula alone	0.015	0.985	0.000
S82.1 Fracture of upper end of tibia	0.014	0.985	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.014	0.986	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.014	0.986	0.000
S80-S89 Injuries to the knee and lower leg	0.014	0.986	0.000
S82.5 Fracture of medial malleolus	0.013	0.987	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.013	0.987	0.000
K04 Diseases of pulp and periapical tissues	0.000	0.987	0.013
S82.6 Fracture of lateral malleolus	0.013	0.987	0.000
K04.8 Radicular cyst	0.000	0.988	0.012
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.012	0.988	0.000
S89 Other and unspecified injuries of lower leg	0.012	0.988	0.000
S82.30 Fracture of lower end of tibia (closed)	0.012	0.988	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.012	0.988	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.988	0.012
F31.8 Other bipolar affective disorders	0.012	0.988	0.000
F31.7 Bipolar affective disorder, currently in remission	0.012	0.988	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.012	0.988	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.011	0.989	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.011	0.989	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.011	0.989	0.000
S82.70 Multiple fractures of lower leg (closed)	0.011	0.989	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.000	0.989	0.011
S82.71 Multiple fractures of lower leg (open)	0.011	0.989	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.011	0.989	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.011	0.989	0.000
S82.21 Fracture of shaft of tibia (open)	0.011	0.989	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.011	0.989	0.000
S82.41 Fracture of fibula alone (open)	0.011	0.989	0.000
S82.11 Fracture of upper end of tibia (open)	0.011	0.989	0.000
S82.31 Fracture of lower end of tibia (open)	0.011	0.989	0.000
S80 Superficial injury of lower leg	0.010	0.990	0.000
S89.8 Other specified injuries of lower leg	0.010	0.990	0.000
I74 Arterial embolism and thrombosis	0.000	0.990	0.010
S88 Traumatic amputation of lower leg	0.010	0.990	0.000
S87 Crushing injury of lower leg	0.010	0.990	0.000
S85 Injury of blood vessels at lower leg level	0.010	0.990	0.000
S84 Injury of nerves at lower leg level	0.010	0.990	0.000
S82.40 Fracture of fibula alone (closed)	0.010	0.990	0.000
S89.9 Unspecified injury of lower leg	0.010	0.990	0.000
S82.10 Fracture of upper end of tibia (closed)	0.010	0.990	0.000
K04.6 Periapical abscess with sinus	0.000	0.990	0.010
S82.51 Fracture of medial malleolus (open)	0.010	0.990	0.000
S83.7 Injury to multiple structures of knee	0.010	0.990	0.000
S83.3 Tear of articular cartilage of knee, current	0.010	0.990	0.000
S83.1 Dislocation of knee	0.010	0.990	0.000
S83.0 Dislocation of patella	0.010	0.990	0.000
K04.3 Abnormal hard tissue formation in pulp	0.000	0.990	0.010
K04.2 Pulp degeneration	0.000	0.990	0.010
K04.1 Necrosis of pulp	0.000	0.990	0.010
S82.61 Fracture of lateral malleolus (open)	0.009	0.990	0.000
S86 Injury of muscle and tendon at lower leg level	0.009	0.990	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.009	0.991	0.000
K04.0 Pulpitis	0.000	0.991	0.009
S89.7 Multiple injuries of lower leg	0.009	0.991	0.000
S89.1 Other specified injuries of lower leg	0.009	0.991	0.000
S89.0 Multiple injuries of lower leg	0.009	0.991	0.000
I77.1 Stricture of artery	0.000	0.991	0.009
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.991	0.009
I71 Aortic aneurysm and dissection	0.000	0.991	0.009
I77 Other disorders of arteries and arterioles	0.000	0.991	0.008
S80.0 Contusion of knee	0.008	0.992	0.000
S80.7 Multiple superficial injuries of lower leg	0.008	0.992	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.992	0.008
S72 Fracture of femur	0.000	0.992	0.008
K04.4 Acute apical periodontitis of pulpal origin	0.000	0.992	0.008
S72.20 Subtrochanteric fracture (closed)	0.000	0.992	0.008
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.008	0.992	0.000
S72.2 Subtrochanteric fracture	0.000	0.992	0.008
S82.50 Fracture of medial malleolus (closed)	0.008	0.992	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.992	0.008
I74.8 Embolism and thrombosis of other arteries	0.000	0.992	0.008
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.992	0.008
I70 Atherosclerosis	0.000	0.992	0.008
S84.9 Injury of unspecified nerve at lower leg level	0.007	0.992	0.000
S84.8 Injury of other nerves at lower leg level	0.007	0.992	0.000
S84.7 Injury of multiple nerves at lower leg level	0.007	0.992	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.007	0.992	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.007	0.992	0.000
S84.0 Injury of tibial nerve at lower leg level	0.007	0.992	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.007	0.992	0.000
S85.8 Injury of other blood vessels at lower leg level	0.007	0.992	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.007	0.992	0.000
S85.5 Injury of popliteal vein	0.007	0.992	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.007	0.992	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.007	0.992	0.000
S85.2 Injury of peroneal artery	0.007	0.992	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.007	0.992	0.000
S85.0 Injury of popliteal artery	0.007	0.992	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.007	0.992	0.000
S87.0 Crushing injury of knee	0.007	0.992	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.007	0.992	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.007	0.992	0.000
S88.0 Traumatic amputation at knee level	0.007	0.992	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.993	0.007
S72.4 Fracture of lower end of femur	0.000	0.993	0.007
S82.60 Fracture of lateral malleolus (closed)	0.007	0.993	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.007	0.993	0.000
S82.8 Fractures of other parts of lower leg	0.007	0.993	0.000
S86.0 Injury of Achilles tendon	0.007	0.993	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.007	0.993	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.007	0.993	0.000
S83.2 Tear of meniscus, current	0.007	0.993	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.993	0.007
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.993	0.007
S72.40 Fracture of lower end of femur (closed)	0.000	0.993	0.007
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.993	0.007
S70-S79 Injuries to the hip and thigh	0.000	0.993	0.007
I70.0 Atherosclerosis of aorta	0.000	0.993	0.007
S80.9 Superficial injury of lower leg, unspecified	0.007	0.993	0.000
S72.1 Pertrochanteric fracture	0.000	0.993	0.007
S72.3 Fracture of shaft of femur	0.000	0.994	0.006
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.994	0.006
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.994	0.006
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.994	0.006
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.994	0.006
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.994	0.006
I77.5 Necrosis of artery	0.000	0.994	0.006
I77.4 Coeliac artery compression syndrome	0.000	0.994	0.006
I77.3 Arterial fibromuscular dysplasia	0.000	0.994	0.006
Z01.6 Radiological examination, not elsewhere classified	0.000	0.994	0.006
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.006	0.994	0.000
S72.0 Fracture of neck of femur	0.000	0.994	0.006
S72.8 Fractures of other parts of femur	0.000	0.994	0.006
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.994	0.006
I77.6 Arteritis, unspecified	0.000	0.994	0.006
I78 Diseases of capillaries	0.000	0.994	0.006
S70 Superficial injury of hip and thigh	0.000	0.994	0.006
S71 Open wound of hip and thigh	0.000	0.994	0.006
I77.2 Rupture of artery	0.000	0.994	0.006
S72.7 Multiple fractures of femur	0.000	0.994	0.006
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.994	0.006
S72.21 Subtrochanteric fracture (open)	0.000	0.994	0.006
S86.8 Injury of other muscles and tendons at lower leg level	0.006	0.994	0.000
Z01.8 Other specified special examinations	0.000	0.994	0.006
I71.0 Dissection of aorta [any part]	0.000	0.994	0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.994	0.006
Z93.0 Tracheostomy status	0.000	0.994	0.006
I70.9 Generalised and unspecified atherosclerosis	0.000	0.994	0.006
I70.8 Atherosclerosis of other arteries	0.000	0.994	0.006
I70.1 Atherosclerosis of renal artery	0.000	0.994	0.006
S72.9 Fracture of femur, part unspecified	0.000	0.994	0.006
S71.1 Open wound of thigh	0.000	0.994	0.006
I77.8 Other specified disorders of arteries and arterioles	0.000	0.994	0.005
S72.41 Fracture of lower end of femur (open)	0.000	0.994	0.005
S72.10 Pertrochanteric fracture (closed)	0.000	0.994	0.005
S79 Other and unspecified injuries of hip and thigh	0.000	0.994	0.005
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.000	0.995	0.005
S82.86 Maisonneuve's fracture	0.005	0.995	0.000
S86.00 Unspecified injury of Achilles tendon	0.005	0.995	0.000
S70.9 Superficial injury of hip and thigh, unspecified	0.000	0.995	0.005
S72.30 Fracture of shaft of femur (closed)	0.000	0.995	0.005
S76 Injury of muscle and tendon at hip and thigh level	0.000	0.995	0.005
I74.5 Embolism and thrombosis of iliac artery	0.000	0.995	0.005
S70.0 Contusion of hip	0.000	0.995	0.005
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.995	0.005
I79.1 Aortitis in diseases classified elsewhere	0.000	0.995	0.005
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.995	0.005
K31.9 Disease of stomach and duodenum, unspecified	0.000	0.995	0.005
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.995	0.005
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.995	0.005
S78 Traumatic amputation of hip and thigh	0.000	0.995	0.005
S77 Crushing injury of hip and thigh	0.000	0.995	0.005
S75 Injury of blood vessels at hip and thigh level	0.000	0.995	0.005
S74 Injury of nerves at hip and thigh level	0.000	0.995	0.005
S81 Open wound of lower leg	0.005	0.995	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.995	0.005
I78.8 Other diseases of capillaries	0.000	0.995	0.005
S72.11 Pertrochanteric fracture (open)	0.000	0.995	0.005
S70.1 Contusion of thigh	0.000	0.995	0.005
S72.31 Fracture of shaft of femur (open)	0.000	0.995	0.005
Z01.7 Laboratory examination	0.000	0.995	0.005
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.995	0.005
S72.80 Fractures of other parts of femur (closed)	0.000	0.995	0.005
S72.00 Fracture of neck of femur (closed)	0.000	0.995	0.005
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.995	0.005
S72.01 Fracture of neck of femur (open)	0.000	0.995	0.005
S72.81 Fractures of other parts of femur (open)	0.000	0.995	0.004
I78.9 Disease of capillaries, unspecified	0.000	0.995	0.005
S70.7 Multiple superficial injuries of hip and thigh	0.000	0.995	0.005
S71.8 Open wound of other and unspecified parts of pelvic girdle	0.000	0.995	0.004
S71.7 Multiple open wounds of of hip and thigh	0.000	0.995	0.004
S71.0 Open wound of hip	0.000	0.995	0.004
S79.9 Unspecified injury of hip and thigh	0.000	0.995	0.005
C15.9 Oesophagus, unspecified	0.005	0.995	0.000
S72.71 Multiple fractures of femur (open)	0.000	0.995	0.004
S72.70 Multiple fractures of femur (closed)	0.000	0.995	0.004
I77.0 Arteriovenous fistula, acquired	0.000	0.995	0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.995	0.004
S73.0 Dislocation of hip	0.000	0.995	0.004
S92.00 Fracture of calcaneus (closed)	0.004	0.995	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.996	0.004
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.996	0.004
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.996	0.004
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.996	0.004
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.996	0.004
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.996	0.004
S72.91 Fracture of femur, part unspecified (open)	0.000	0.996	0.004
S82.81 Fractures of other parts of lower leg (open)	0.004	0.996	0.000
G93.9 Disorder of brain, unspecified	0.000	0.996	0.004
I73 Other peripheral vascular diseases	0.000	0.996	0.004
S92.0 Fracture of calcaneus	0.004	0.996	0.000
S80.8 Other superficial injuries of lower leg	0.004	0.996	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.000	0.996	0.004
S92 Fracture of foot, except ankle	0.004	0.996	0.000
S73.1 Sprain and strain of hip	0.000	0.996	0.004
S79.7 Multiple injuries of hip and thigh	0.000	0.996	0.004
S70.8 Other superficial injuries of hip and thigh	0.000	0.996	0.004
G93.8 Other specified disorders of brain	0.000	0.996	0.004
S76.1 Injury of quadriceps muscle and tendon	0.000	0.996	0.004
S76.7 Injury of multiple muscles and tendons at hip and thigh level	0.000	0.996	0.004
S76.3 Injury of muscle and tendon of the posterior muscle group at thigh level	0.000	0.996	0.004
S76.2 Injury of adductor muscle and tendon of thigh	0.000	0.996	0.004
S76.0 Injury of muscle and tendon of hip	0.000	0.996	0.004
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.996	0.004
M54.5 Low back pain	0.004	0.996	0.000
S79.8 Other specified injuries of hip and thigh	0.000	0.996	0.004
S74.9 Injury of unspecified nerve at hip and thigh level	0.000	0.996	0.004
S74.8 Injury of other nerves at hip and thigh level	0.000	0.996	0.004
S74.7 Injury of multiple nerves at hip and thigh level	0.000	0.996	0.004
S74.2 Injury of cutaneous sensory nerve at hip and thigh level	0.000	0.996	0.004
S74.1 Injury of femoral nerve at hip and thigh level	0.000	0.996	0.004
S74.0 Injury of sciatic nerve at hip and thigh level	0.000	0.996	0.004
S75.9 Injury of unspecified blood vessel at hip and thigh level	0.000	0.996	0.004
S75.8 Injury of other blood vessels at hip and thigh level	0.000	0.996	0.004
S75.7 Injury of multiple blood vessels at hip and thigh level	0.000	0.996	0.004
S75.2 Injury of greater saphenous vein at hip and thigh level	0.000	0.996	0.004
S75.1 Injury of femoral vein at hip and thigh level	0.000	0.996	0.004
S75.0 Injury of femoral artery	0.000	0.996	0.004
S77.2 Crushing injury of hip with thigh	0.000	0.996	0.004
S77.1 Crushing injury of thigh	0.000	0.996	0.004
S77.0 Crushing injury of hip	0.000	0.996	0.004
S78.9 Traumatic amputation of hip and thigh, level unspecified	0.000	0.996	0.004
S78.1 Traumatic amputation at level between hip and knee	0.000	0.996	0.004
S78.0 Traumatic amputation at hip joint	0.000	0.996	0.004
S92.5 Fracture of other toe	0.004	0.996	0.000
C15.5 Lower third of oesophagus	0.004	0.996	0.000
I73.8 Other specified peripheral vascular diseases	0.000	0.996	0.004
S81.7 Multiple open wounds of lower leg	0.004	0.996	0.000
G93.0 Cerebral cysts	0.000	0.996	0.004
G93 Other disorders of brain	0.000	0.996	0.004
I72 Other aneurysm	0.000	0.996	0.004
S92.50 Fracture of other toe (closed)	0.004	0.996	0.000
S92.3 Fracture of metatarsal bone	0.004	0.996	0.000
Z01.3 Examination of blood pressure	0.000	0.996	0.004
Z01.1 Examination of ears and hearing	0.000	0.996	0.004
Z01.0 Examination of eyes and vision	0.000	0.996	0.004
S81.8 Open wound of other parts of lower leg	0.003	0.996	0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)	0.004	0.996	0.000
Z01.9 Special examination, unspecified	0.000	0.996	0.003
C15 Malignant neoplasm of oesophagus	0.003	0.997	0.000
G93.2 Benign intracranial hypertension	0.000	0.997	0.003
M67.2 Synovial hypertrophy, not elsewhere classified	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
M54.54 Low back pain-Thoracic	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.997	0.003
S92.01 Fracture of calcaneus (open)	0.003	0.997	0.000
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
S92.30 Fracture of metatarsal bone (closed)	0.003	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
K04.5 Chronic apical periodontitis	0.000	0.997	0.003
S92.51 Fracture of other toe (open)	0.003	0.997	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.003	0.997	0.000
S76.10 Unspecified injury of quadriceps muscle, fascia and tendon	0.000	0.997	0.003
G93.4 Encephalopathy, unspecified	0.000	0.997	0.003
S99 Other and unspecified injuries of ankle and foot	0.003	0.997	0.000
M54.53 Low back pain-Cervicothoracic	0.003	0.997	0.000
M54.52 Low back pain-Cervical	0.003	0.997	0.000
M54.51 Low back pain-Occipit-atl-axl	0.003	0.997	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
I72.3 Aneurysm of iliac artery	0.000	0.997	0.003
M54.55 Low back pain (Thoracolumbar region)	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
F52.2 Failure of genital response	0.000	0.997	0.003
G93.7 Reye's syndrome	0.000	0.997	0.003
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
S92.40 Fracture of great toe (closed)	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
S99.9 Unspecified injury of ankle and foot	0.003	0.997	0.000
S92.31 Fracture of metatarsal bone (open)	0.003	0.997	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.003	0.997	0.000
G93.5 Compression of brain	0.000	0.997	0.003
I72.2 Aneurysm of renal artery	0.000	0.997	0.003
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.997	0.003
I72.9 Aneurysm of unspecified site	0.000	0.997	0.003
Z01.4 Gynaecological examination (general)(routine)	0.000	0.997	0.003
Z01.2 Dental examination	0.000	0.997	0.003
I78.1 Naevus, nonneoplastic	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.003	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.003	0.997	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.997	0.000
C15.2 Abdominal part of oesophagus	0.003	0.997	0.000
C15.0 Cervical part of oesophagus	0.003	0.997	0.000
M54.50 Low back pain (Multiple sites in spine)	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
I47.2 Ventricular tachycardia	0.000	0.997	0.003
S92.20 Fracture of other tarsal bone(s) (closed)	0.003	0.997	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.997	0.000
S93.4 Sprain and strain of ankle	0.003	0.997	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.003	0.997	0.000
S93.5 Sprain and strain of toe(s)	0.003	0.997	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.003	0.997	0.000
S93.0 Dislocation of ankle joint	0.003	0.997	0.000
S42.20 Fracture of upper end of humerus (closed)	0.003	0.997	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.997	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.997	0.000
G93.6 Cerebral oedema	0.000	0.997	0.003
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
S92.41 Fracture of great toe (open)	0.002	0.997	0.000
E06.3 Autoimmune thyroiditis	0.000	0.997	0.003
N50 Other disorders of male genital organs	0.003	0.997	0.000
C15.4 Middle third of oesophagus	0.002	0.997	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.997	0.002
F30-F39 Mood [affective] disorders	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.002	0.997	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.002
K72.9 Hepatic failure, unspecified	0.000	0.997	0.003
M54.59 Low back pain (Site unspecified)	0.002	0.998	0.000
I72.0 Aneurysm of carotid artery	0.000	0.998	0.002
M24.23 Disorder of ligament (Forearm)	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
S91 Open wound of ankle and foot	0.002	0.998	0.000
J94.8 Other specified pleural conditions	0.002	0.998	0.000
C15.3 Upper third of oesophagus	0.002	0.998	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.998	0.002
I73.9 Peripheral vascular disease, unspecified	0.000	0.998	0.002
Z01.5 Diagnostic skin and sensitisation tests	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.998	0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin	0.000	0.998	0.002
G93.3 Postviral fatigue syndrome	0.000	0.998	0.002
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.998	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.998	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.998	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.998	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.998	0.000
S94.1 Injury of medial plantar nerve	0.002	0.998	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.998	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.998	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.998	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.998	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.998	0.000
S95.1 Injury of plantar artery of foot	0.002	0.998	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.998	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.998	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.998	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.998	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.998	0.000
S97.1 Crushing injury of toe(s)	0.002	0.998	0.000
S97.0 Crushing injury of ankle	0.002	0.998	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.998	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.998	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.998	0.000
S98.1 Traumatic amputation of one toe	0.002	0.998	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.998	0.000
F39 Unspecified mood [affective] disorder	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.002	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
S81.0 Open wound of knee	0.002	0.998	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.002	0.998	0.000
Z96.0 Presence of urogenital implants	0.000	0.998	0.002
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
M24.2 Disorder of ligament	0.002	0.998	0.000
F38 Other mood [affective] disorders	0.002	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
M24.1 Other articular cartilage disorders	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
F34 Persistent mood [affective] disorders	0.002	0.998	0.000
M24.13 Other articular cartilage disorders (Forearm)	0.002	0.998	0.000
M24.28 Disorder of ligament (Other)	0.002	0.998	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.002	0.998	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
S90.1 Contusion of toe(s) without damage to nail	0.002	0.998	0.000
S90.0 Contusion of ankle	0.002	0.998	0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.002	0.998	0.000
C44.2 Skin of ear and external auricular canal	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.002	0.998	0.000
S91.2 Open wound of toe(s) with damage to nail	0.002	0.998	0.000
Z93.5 Cystostomy status	0.000	0.998	0.002
N50.9 Disorder of male genital organs, unspecified	0.002	0.998	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
M24.17 Other articular cartilage disorders (Ankle and foot)	0.002	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.002	0.998	0.000
Q83.8 Other congenital malformations of breast	0.002	0.998	0.000
Z71.9 Counselling, unspecified	0.000	0.998	0.002
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.002
R60.9 Oedema, unspecified	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
S21.2 Open wound of back wall of thorax	0.002	0.998	0.000
F52 Sexual dysfunction, not caused by organic disorder or disease	0.000	0.998	0.002
S22.00 Fracture of thoracic vertebra (closed)	0.002	0.998	0.000
S90.3 Contusion of other and unspecified parts of foot	0.002	0.998	0.000
Z93.1 Gastrostomy status	0.000	0.998	0.002
M24 Other specific joint derangements	0.002	0.998	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
M67.43 Ganglion, wrist	0.002	0.998	0.000
E06.9 Thyroiditis, unspecified	0.000	0.998	0.002
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M67.4 Ganglion	0.002	0.998	0.000
C78.2 Secondary malignant neoplasm of pleura	0.000	0.998	0.002
M24.29 Disorder of ligament (Site unspecified)	0.002	0.998	0.000
M24.25 Disorder of ligament (Pelvic region and thigh)	0.002	0.998	0.000
M24.22 Disorder of ligament (Upper arm)	0.002	0.998	0.000
M24.20 Disorder of ligament (Multiple sites)	0.002	0.998	0.000
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
F38.8 Other specified mood [affective] disorders	0.002	0.998	0.000
F38.1 Other recurrent mood [affective] disorders	0.002	0.998	0.000
F38.0 Other single mood [affective] disorders	0.002	0.998	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.002	0.998	0.000
M24.18 Other articular cartilage disorders (Other)	0.002	0.998	0.000
M24.14 Other articular cartilage disorders (Hand)	0.002	0.998	0.000
M24.12 Other articular cartilage disorders (Upper arm)	0.002	0.998	0.000
M24.10 Other articular cartilage disorders (Multiple sites)	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S20 Superficial injury of thorax	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
M24.7 Protrusio acetabuli	0.002	0.998	0.000
S42.2 Fracture of upper end of humerus	0.002	0.998	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.002	0.998	0.000
M67.47 Ganglion, ankle and foot	0.002	0.998	0.000
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.002	0.998	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
F42.9 Obsessive-compulsive disorder, unspecified	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
Q60.2 Renal agenesis, unspecified	0.002	0.998	0.000
M24.75 Protrusio acetabuli-Pelvic/thigh	0.002	0.998	0.000
F34.9 Persistent mood [affective] disorder, unspecified	0.001	0.998	0.000
F34.8 Other persistent mood [affective] disorders	0.001	0.998	0.000
F34.0 Cyclothymia	0.001	0.998	0.000
S27.1 Traumatic haemothorax	0.002	0.998	0.000
E06 Thyroiditis	0.000	0.998	0.002
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
M67 Other disorders of synovium and tendon	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
M54.56 Low back pain (Lumbar region)	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations