TreeWAS – Variant ID: rs12053254

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K35.9 Acute appendicitis, unspecified	0.314	0.686	0.000
K35 Acute appendicitis	0.253	0.747	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.215	0.785	0.000
K35.3 Acute appendicitis with localized peritonitis	0.214	0.786	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.181	0.819	0.000
K35.8 Acute appendicitis, other and unspecified	0.166	0.834	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.164	0.836	0.000
K35-K38 Diseases of appendix	0.149	0.851	0.000
K36 Other appendicitis	0.120	0.880	0.000
K38 Other diseases of appendix	0.120	0.880	0.000
K38.9 Disease of appendix, unspecified	0.098	0.902	0.000
K38.1 Appendicular concretions	0.088	0.912	0.000
K37 Unspecified appendicitis	0.088	0.912	0.000
K38.3 Fistula of appendix	0.086	0.914	0.000
K38.2 Diverticulum of appendix	0.086	0.914	0.000
K38.0 Hyperplasia of appendix	0.086	0.914	0.000
K38.8 Other specified diseases of appendix	0.085	0.915	0.000
K81.9 Cholecystitis, unspecified	0.053	0.947	0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.048	0.952	0.000
K81 Cholecystitis	0.048	0.952	0.000
K11 Diseases of salivary glands	0.047	0.953	0.000
K11.5 Sialolithiasis	0.046	0.954	0.000
Chapter XI Diseases of the digestive system	0.046	0.954	0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws	0.044	0.956	0.000
K09 Cysts of oral region, not elsewhere classified	0.042	0.957	0.000
K85 Acute pancreatitis	0.042	0.958	0.000
K11.2 Sialoadenitis	0.042	0.958	0.000
K90-K93 Other diseases of the digestive system	0.040	0.960	0.000
K11.8 Other diseases of salivary glands	0.039	0.961	0.000
K90 Intestinal malabsorption	0.039	0.961	0.000
K83 Other diseases of biliary tract	0.038	0.962	0.000
K10 Other diseases of jaws	0.038	0.962	0.000
K02 Dental caries	0.038	0.962	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.037	0.963	0.000
K09.0 Developmental odontogenic cysts	0.037	0.963	0.000
K11.6 Mucocele of salivary gland	0.037	0.963	0.000
K85.2 Alcohol-induced acute pancreatitis	0.036	0.964	0.000
K85.8 Other acute pancreatitis	0.036	0.964	0.000
K82 Other diseases of gallbladder	0.036	0.964	0.000
K09.8 Other cysts of oral region, not elsewhere classified	0.036	0.964	0.000
K11.9 Disease of salivary gland, unspecified	0.036	0.964	0.000
K90.0 Coeliac disease	0.035	0.965	0.000
K80 Cholelithiasis	0.035	0.965	0.000
K09.2 Other cysts of jaw	0.035	0.965	0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere	0.035	0.965	0.000
K86 Other diseases of pancreas	0.035	0.965	0.000
K81.8 Other cholecystitis	0.034	0.966	0.000
K11.7 Disturbances of salivary secretion	0.034	0.966	0.000
K11.4 Fistula of salivary gland	0.034	0.966	0.000
K11.3 Abscess of salivary gland	0.034	0.966	0.000
K11.0 Atrophy of salivary gland	0.034	0.966	0.000
K83.0 Cholangitis	0.034	0.966	0.000
K65-K67 Diseases of peritoneum	0.034	0.966	0.000
K11.1 Hypertrophy of salivary gland	0.034	0.966	0.000
K90.9 Intestinal malabsorption, unspecified	0.033	0.967	0.000
K01 Embedded and impacted teeth	0.033	0.967	0.000
K85.9 Acute pancreatitis, unspecified	0.033	0.967	0.000
K80.4 Calculus of bile duct with cholecystitis	0.033	0.967	0.000
K02.9 Dental caries, unspecified	0.032	0.968	0.000
K03 Other diseases of hard tissues of teeth	0.032	0.968	0.000
K09.9 Cyst of oral region, unspecified	0.031	0.969	0.000
K09.1 Developmental (nonodontogenic) cysts of oral region	0.031	0.969	0.000
K85.3 Drug-induced acute pancreatitis	0.031	0.969	0.000
K85.0 Idiopathic acute pancreatitis	0.031	0.969	0.000
K82.8 Other specified diseases of gallbladder	0.030	0.970	0.000
S82.8 Fractures of other parts of lower leg	0.030	0.970	0.000
K10.8 Other specified diseases of jaws	0.030	0.970	0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified	0.030	0.970	0.000
K14 Diseases of tongue	0.030	0.970	0.000
K10.0 Developmental disorders of jaws	0.029	0.970	0.000
K00 Disorders of tooth development and eruption	0.029	0.970	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.971	0.029
K80.0 Calculus of gallbladder with acute cholecystitis	0.029	0.971	0.000
K10.2 Inflammatory conditions of jaws	0.029	0.971	0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis	0.029	0.971	0.000
K07 Dentofacial anomalies [including malocclusion]	0.029	0.971	0.000
K86.0 Alcohol-induced chronic pancreatitis	0.029	0.971	0.000
K93 Disorders of other digestive organs in diseases classified elsewhere	0.029	0.971	0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified	0.029	0.971	0.000
K06 Other disorders of gingiva and edentulous alveolar ridge	0.029	0.971	0.000
K90.8 Other intestinal malabsorption	0.028	0.972	0.000
K90.3 Pancreatic steatorrhoea	0.028	0.972	0.000
K90.2 Blind loop syndrome, not elsewhere classified	0.028	0.972	0.000
K90.1 Tropical sprue	0.028	0.972	0.000
K80.8 Other cholelithiasis	0.028	0.972	0.000
K02.8 Other dental caries	0.028	0.972	0.000
K83.9 Disease of biliary tract, unspecified	0.027	0.972	0.000
K83.5 Biliary cyst	0.027	0.972	0.000
K83.4 Spasm of sphincter of Oddi	0.027	0.972	0.000
K83.3 Fistula of bile duct	0.027	0.972	0.000
K83.2 Perforation of bile duct	0.027	0.972	0.000
K83.1 Obstruction of bile duct	0.027	0.973	0.000
K10.9 Disease of jaws, unspecified	0.027	0.973	0.000
K10.3 Alveolitis of jaws	0.027	0.973	0.000
K10.1 Giant cell granuloma, central	0.027	0.973	0.000
K02.5 Caries with pulp exposure	0.027	0.973	0.000
K02.4 Odontoclasia	0.027	0.973	0.000
K02.3 Arrested dental caries	0.027	0.973	0.000
K02.2 Caries of cementum	0.027	0.973	0.000
K02.1 Caries of dentin	0.027	0.973	0.000
K02.0 Caries limited to enamel	0.027	0.973	0.000
K86.3 Pseudocyst of pancreas	0.027	0.973	0.000
K66 Other disorders of peritoneum	0.027	0.973	0.000
K12 Stomatitis and related lesions	0.027	0.973	0.000
K86.9 Disease of pancreas, unspecified	0.026	0.974	0.000
K04 Diseases of pulp and periapical tissues	0.026	0.974	0.000
K01.0 Embedded teeth	0.026	0.974	0.000
K82.3 Fistula of gallbladder	0.026	0.974	0.000
K82.2 Perforation of gallbladder	0.026	0.974	0.000
K82.0 Obstruction of gallbladder	0.026	0.974	0.000
K82.4 Cholesterolosis of gallbladder	0.026	0.974	0.000
K81.0 Acute cholecystitis	0.026	0.974	0.000
K80.3 Calculus of bile duct with cholangitis	0.026	0.974	0.000
K86.1 Other chronic pancreatitis	0.025	0.974	0.000
K91.3 Postoperative intestinal obstruction	0.025	0.975	0.000
K87.1 Disorders of pancreas in diseases classified elsewhere	0.025	0.975	0.000
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere	0.025	0.975	0.000
K14.9 Disease of tongue, unspecified	0.025	0.975	0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere	0.025	0.975	0.000
K85.1 Biliary acute pancreatitis	0.024	0.976	0.000
N85.4 Malposition of uterus	0.000	0.976	0.024
K82.9 Disease of gallbladder, unspecified	0.024	0.976	0.000
S82 Fracture of lower leg, including ankle	0.024	0.976	0.000
K13 Other diseases of lip and oral mucosa	0.024	0.976	0.000
K82.1 Hydrops of gallbladder	0.023	0.976	0.000
N85 Other noninflammatory disorders of uterus, except cervix	0.000	0.976	0.024
S82.81 Fractures of other parts of lower leg (open)	0.023	0.977	0.000
K03.9 Disease of hard tissues of teeth, unspecified	0.023	0.977	0.000
K03.8 Other specified diseases of hard tissues of teeth	0.023	0.977	0.000
K03.7 Posteruptive colour changes of dental hard tissues	0.023	0.977	0.000
K03.6 Deposits [accretions] on teeth	0.023	0.977	0.000
K03.5 Ankylosis of teeth	0.023	0.977	0.000
K03.4 Hypercementosis	0.023	0.977	0.000
K03.3 Pathological resorption of teeth	0.023	0.977	0.000
K03.2 Erosion of teeth	0.023	0.977	0.000
K03.1 Abrasion of teeth	0.023	0.977	0.000
K03.0 Excessive attrition of teeth	0.023	0.977	0.000
K04.4 Acute apical periodontitis of pulpal origin	0.023	0.977	0.000
K91.0 Vomiting following gastro-intestinal surgery	0.023	0.977	0.000
K07.4 Malocclusion, unspecified	0.023	0.977	0.000
K66.8 Other specified disorders of peritoneum	0.023	0.977	0.000
K65 Peritonitis	0.023	0.977	0.000
K04.0 Pulpitis	0.022	0.978	0.000
S82.86 Maisonneuve's fracture	0.022	0.978	0.000
K81.1 Chronic cholecystitis	0.022	0.978	0.000
S82.0 Fracture of patella	0.022	0.978	0.000
K01.1 Impacted teeth	0.022	0.978	0.000
K86.2 Cyst of pancreas	0.021	0.978	0.000
K14.6 Glossodynia	0.021	0.979	0.000
K14.5 Plicated tongue	0.021	0.979	0.000
K14.4 Atrophy of tongue papillae	0.021	0.979	0.000
K14.3 Hypertrophy of tongue papillae	0.021	0.979	0.000
K14.2 Median rhomboid glossitis	0.021	0.979	0.000
K14.1 Geographic tongue	0.021	0.979	0.000
K00.9 Disorder of tooth development, unspecified	0.021	0.979	0.000
K00.8 Other disorders of tooth development	0.021	0.979	0.000
K00.7 Teething syndrome	0.021	0.979	0.000
K00.5 Hereditary disturbances in tooth structure, not elsewhere classified	0.021	0.979	0.000
K00.4 Disturbances in tooth formation	0.021	0.979	0.000
K00.3 Mottled teeth	0.021	0.979	0.000
K00.2 Abnormalities of size and form of teeth	0.021	0.979	0.000
K00.1 Supernumerary teeth	0.021	0.979	0.000
K00.0 Anodontia	0.021	0.979	0.000
K14.0 Glossitis	0.021	0.979	0.000
K12.3 Oral mucositis (ulcerative)	0.021	0.979	0.000
K07.9 Dentofacial anomaly, unspecified	0.021	0.979	0.000
K07.8 Other dentofacial anomalies	0.021	0.979	0.000
K07.5 Dentofacial functional abnormalities	0.021	0.979	0.000
K07.2 Anomalies of dental arch relationship	0.021	0.979	0.000
K07.1 Anomalies of jaw-cranial base relationship	0.021	0.979	0.000
K07.0 Major anomalies of jaw size	0.021	0.979	0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere	0.021	0.979	0.000
K93.1 Megacolon in Chagas' disease	0.021	0.979	0.000
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands	0.021	0.979	0.000
K91.9 Postprocedural disorder of digestive system, unspecified	0.021	0.979	0.000
K91.5 Postcholecystectomy syndrome	0.021	0.979	0.000
K91.2 Postsurgical malabsorption, not elsewhere classified	0.021	0.979	0.000
K91.1 Postgastric surgery syndromes	0.021	0.979	0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified	0.021	0.979	0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma	0.021	0.979	0.000
K06.1 Gingival enlargement	0.021	0.979	0.000
K06.0 Gingival recession	0.021	0.979	0.000
K05 Gingivitis and periodontal diseases	0.020	0.979	0.000
I27.2 Other secondary pulmonary hypertension	0.000	0.980	0.020
S82.00 Fracture of patella (closed)	0.020	0.980	0.000
K83.8 Other specified diseases of biliary tract	0.020	0.980	0.000
K66.9 Disorder of peritoneum, unspecified	0.019	0.980	0.000
K66.1 Haemoperitoneum	0.019	0.980	0.000
S82.2 Fracture of shaft of tibia	0.019	0.981	0.000
K04.3 Abnormal hard tissue formation in pulp	0.019	0.981	0.000
K04.2 Pulp degeneration	0.019	0.981	0.000
K04.1 Necrosis of pulp	0.019	0.981	0.000
K86.8 Other specified diseases of pancreas	0.019	0.981	0.000
S82.4 Fracture of fibula alone	0.019	0.981	0.000
K00.6 Disturbances in tooth eruption	0.019	0.981	0.000
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction	0.018	0.981	0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa	0.018	0.981	0.000
K12.0 Recurrent oral aphthae	0.018	0.982	0.000
K07.6 Temporomandibular joint disorders	0.018	0.982	0.000
K04.6 Periapical abscess with sinus	0.018	0.982	0.000
K65.8 Other peritonitis	0.018	0.982	0.000
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere	0.018	0.982	0.000
K67.3 Tuberculous peritonitis	0.018	0.982	0.000
K67.2 Syphilitic peritonitis	0.018	0.982	0.000
K67.1 Gonococcal peritonitis	0.018	0.982	0.000
K67.0 Chlamydial peritonitis	0.018	0.982	0.000
K66.0 Peritoneal adhesions	0.018	0.982	0.000
K07.3 Anomalies of tooth position	0.017	0.982	0.000
K04.8 Radicular cyst	0.018	0.982	0.000
S82.6 Fracture of lateral malleolus	0.017	0.983	0.000
S82.9 Fracture of lower leg, part unspecified	0.017	0.983	0.000
S82.7 Multiple fractures of lower leg	0.017	0.983	0.000
N85.1 Endometrial adenomatous hyperplasia	0.000	0.983	0.017
S82.3 Fracture of lower end of tibia	0.017	0.983	0.000
S82.5 Fracture of medial malleolus	0.017	0.983	0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge	0.017	0.983	0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue	0.017	0.983	0.000
K13.6 Irritative hyperplasia of oral mucosa	0.017	0.983	0.000
K13.5 Oral submucous fibrosis	0.017	0.983	0.000
K13.3 Hairy leukoplakia	0.017	0.983	0.000
K13.1 Cheek and lip biting	0.017	0.983	0.000
K65.0 Acute peritonitis	0.017	0.983	0.000
N85.7 Haematometra	0.000	0.983	0.017
N85.6 Intra-uterine synechiae	0.000	0.983	0.017
N85.5 Inversion of uterus	0.000	0.983	0.017
N85.3 Subinvolution of uterus	0.000	0.983	0.017
K04.5 Chronic apical periodontitis	0.017	0.983	0.000
K12.2 Cellulitis and abscess of mouth	0.016	0.984	0.000
K12.1 Other forms of stomatitis	0.016	0.984	0.000
S82.1 Fracture of upper end of tibia	0.016	0.984	0.000
N85.9 Noninflammatory disorder of uterus, unspecified	0.000	0.984	0.016
N85.2 Hypertrophy of uterus	0.000	0.984	0.016
S82.01 Fracture of patella (open)	0.016	0.984	0.000
S82.20 Fracture of shaft of tibia (closed)	0.016	0.984	0.000
N85.0 Endometrial glandular hyperplasia	0.000	0.984	0.016
S82.40 Fracture of fibula alone (closed)	0.015	0.985	0.000
K05.2 Acute periodontitis	0.015	0.985	0.000
K05.5 Other periodontal diseases	0.015	0.985	0.000
K05.4 Periodontosis	0.015	0.985	0.000
K05.0 Acute gingivitis	0.015	0.985	0.000
K91.4 Colostomy and enterostomy malfunction	0.015	0.985	0.000
K05.1 Chronic gingivitis	0.015	0.985	0.000
S82.21 Fracture of shaft of tibia (open)	0.015	0.985	0.000
K40-K46 Hernia	0.015	0.985	0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.014	0.985	0.000
S82.41 Fracture of fibula alone (open)	0.014	0.986	0.000
R87.6 Abnormal cytological findings	0.014	0.986	0.000
R87 Abnormal findings in specimens from female genital organs	0.013	0.987	0.000
K92 Other diseases of digestive system	0.013	0.987	0.000
S82.31 Fracture of lower end of tibia (open)	0.013	0.987	0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues	0.013	0.987	0.000
K50.1 Crohn's disease of large intestine	0.000	0.987	0.013
I27 Other pulmonary heart diseases	0.000	0.987	0.013
R87.7 Abnormal histological findings	0.013	0.987	0.000
S82.61 Fracture of lateral malleolus (open)	0.013	0.987	0.000
S82.60 Fracture of lateral malleolus (closed)	0.013	0.987	0.000
S82.71 Multiple fractures of lower leg (open)	0.013	0.987	0.000
S82.70 Multiple fractures of lower leg (closed)	0.013	0.987	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.013	0.987	0.000
S82.90 Fracture of lower leg, part unspecified (closed)	0.013	0.987	0.000
K04.7 Periapical abscess without sinus	0.013	0.987	0.000
S82.51 Fracture of medial malleolus (open)	0.013	0.987	0.000
K46 Unspecified abdominal hernia	0.013	0.987	0.000
K13.29 Other disturbances of oral epithelium, including tongue	0.012	0.987	0.000
K50.9 Crohn's disease, unspecified	0.000	0.987	0.013
S82.50 Fracture of medial malleolus (closed)	0.012	0.987	0.000
K13.0 Diseases of lips	0.012	0.987	0.000
K13.7 Other and unspecified lesions of oral mucosa	0.013	0.987	0.000
K05.6 Periodontal disease, unspecified	0.012	0.988	0.000
S82.30 Fracture of lower end of tibia (closed)	0.012	0.988	0.000
K50 Crohn's disease [regional enteritis]	0.001	0.988	0.012
S82.11 Fracture of upper end of tibia (open)	0.012	0.988	0.000
K92.8 Other specified diseases of digestive system	0.011	0.989	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.011	0.989	0.000
K05.22 Aggressive periodontitis, generalized	0.011	0.989	0.000
K45 Other abdominal hernia	0.011	0.989	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.989	0.011
R87.9 Unspecified abnormal finding	0.011	0.989	0.000
K14.8 Other diseases of tongue	0.010	0.989	0.000
K65.9 Peritonitis, unspecified	0.010	0.990	0.000
K43 Ventral hernia	0.010	0.990	0.000
S82.10 Fracture of upper end of tibia (closed)	0.010	0.990	0.000
K41 Femoral hernia	0.010	0.990	0.000
R87.8 Other abnormal findings	0.010	0.990	0.000
R87.5 Abnormal microbiological findings	0.010	0.990	0.000
R87.4 Abnormal immunological findings	0.010	0.990	0.000
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.010	0.990	0.000
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.010	0.990	0.000
R87.1 Abnormal level of hormones	0.010	0.990	0.000
R87.0 Abnormal level of enzymes	0.010	0.990	0.000
I27.8 Other specified pulmonary heart diseases	0.000	0.990	0.009
I27.1 Kyphoscoliotic heart disease	0.000	0.990	0.009
K05.3 Chronic periodontitis	0.009	0.991	0.000
K46.1 Unspecified abdominal hernia with gangrene	0.009	0.991	0.000
K46.0 Unspecified abdominal hernia with obstruction, without gangrene	0.009	0.991	0.000
Z80.0 Family history of malignant neoplasm of digestive organs	0.009	0.991	0.000
K50.0 Crohn's disease of small intestine	0.000	0.991	0.009
I27.0 Primary pulmonary hypertension	0.000	0.991	0.009
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.009	0.991	0.000
K92.1 Melaena	0.009	0.991	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.009	0.991	0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.009	0.991	0.000
K08 Other disorders of teeth and supporting structures	0.008	0.991	0.001
K92.9 Disease of digestive system, unspecified	0.009	0.991	0.000
K50.8 Other Crohn's disease	0.001	0.991	0.008
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.008	0.991	0.000
K45.1 Other specified abdominal hernia with gangrene	0.008	0.992	0.000
K45.0 Other specified abdominal hernia with obstruction, without gangrene	0.008	0.992	0.000
K43.9 Ventral hernia without obstruction or gangrene	0.008	0.992	0.000
R86 Abnormal findings in specimens from male genital organs	0.008	0.992	0.000
K50-K52 Noninfective enteritis and colitis	0.006	0.992	0.002
K70-K77 Diseases of liver	0.008	0.992	0.000
R30.0 Dysuria	0.000	0.992	0.008
G47.3 Sleep apnoea	0.008	0.992	0.000
R86.8 Other abnormal findings	0.008	0.992	0.000
K43.7 Other and unspecified ventral hernia with gangrene	0.007	0.992	0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene	0.007	0.992	0.000
K43.5 Parastomal hernia without obstruction or gangrene	0.007	0.992	0.000
K43.4 Parastomal hernia with gangrene	0.007	0.992	0.000
K43.3 Parastomal hernia with obstruction, without gangrene	0.007	0.992	0.000
K43.2 Incisional hernia without obstruction or gangrene	0.007	0.992	0.000
K43.1 Ventral hernia with gangrene	0.007	0.992	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.007	0.992	0.000
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.007	0.992	0.000
K41.1 Bilateral femoral hernia, with gangrene	0.007	0.992	0.000
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.007	0.992	0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.007	0.993	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.007	0.993	0.000
K08.9 Disorder of teeth and supporting structures, unspecified	0.006	0.993	0.000
K42 Umbilical hernia	0.007	0.993	0.000
K08.0 Exfoliation of teeth due to systemic causes	0.006	0.993	0.001
R89 Abnormal findings in specimens from other organs, systems and tissues	0.007	0.993	0.000
R83 Abnormal findings in cerebrospinal fluid	0.007	0.993	0.000
S80-S89 Injuries to the knee and lower leg	0.007	0.993	0.000
K08.2 Atrophy of edentulous alveolar ridge	0.006	0.994	0.001
K43.0 Ventral hernia with obstruction, without gangrene	0.006	0.994	0.000
R86.9 Unspecified abnormal finding	0.006	0.994	0.000
R86.7 Abnormal histological findings	0.006	0.994	0.000
R86.6 Abnormal cytological findings	0.006	0.994	0.000
R86.5 Abnormal microbiological findings	0.006	0.994	0.000
R86.4 Abnormal immunological findings	0.006	0.994	0.000
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.006	0.994	0.000
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.006	0.994	0.000
R86.1 Abnormal level of hormones	0.006	0.994	0.000
R86.0 Abnormal level of enzymes	0.006	0.994	0.000
K73 Chronic hepatitis, not elsewhere classified	0.006	0.994	0.000
K44 Diaphragmatic hernia	0.006	0.994	0.000
K77 Liver disorders in diseases classified elsewhere	0.006	0.994	0.000
K71 Toxic liver disease	0.006	0.994	0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease	0.005	0.994	0.001
R85.5 Abnormal microbiological findings	0.006	0.994	0.000
S81 Open wound of lower leg	0.006	0.994	0.000
K72 Hepatic failure, not elsewhere classified	0.006	0.994	0.000
K40 Inguinal hernia	0.006	0.994	0.000
G40.9 Epilepsy, unspecified	0.006	0.994	0.000
K75 Other inflammatory liver diseases	0.006	0.994	0.000
G47 Sleep disorders	0.006	0.994	0.000
R84.5 Abnormal microbiological findings	0.005	0.995	0.000
R85.9 Unspecified abnormal finding	0.005	0.995	0.000
R85.8 Other abnormal findings	0.005	0.995	0.000
R85.7 Abnormal histological findings	0.005	0.995	0.000
R85.6 Abnormal cytological findings	0.005	0.995	0.000
R85.4 Abnormal immunological findings	0.005	0.995	0.000
R85.3 Abnormal level of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R85.2 Abnormal level of other drugs, medicaments and biological substances	0.005	0.995	0.000
R85.1 Abnormal level of hormones	0.005	0.995	0.000
R85.0 Abnormal level of enzymes	0.005	0.995	0.000
S81.0 Open wound of knee	0.005	0.995	0.000
G40 Epilepsy	0.005	0.995	0.000
R84.9 Unspecified abnormal finding	0.005	0.995	0.000
R84.8 Other abnormal findings	0.005	0.995	0.000
R84.7 Abnormal histological findings	0.005	0.995	0.000
R84.6 Abnormal cytological findings	0.005	0.995	0.000
R84.4 Abnormal immunological findings	0.005	0.995	0.000
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.005	0.995	0.000
R84.1 Abnormal level of hormones	0.005	0.995	0.000
R84.0 Abnormal level of enzymes	0.005	0.995	0.000
K42.1 Umbilical hernia with gangrene	0.005	0.995	0.000
R83.9 Unspecified abnormal finding	0.005	0.995	0.000
R83.8 Other abnormal findings	0.005	0.995	0.000
R83.7 Abnormal histological findings	0.005	0.995	0.000
R83.6 Abnormal cytological findings	0.005	0.995	0.000
R83.5 Abnormal microbiological findings	0.005	0.995	0.000
R83.4 Abnormal immunological findings	0.005	0.995	0.000
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.005	0.995	0.000
R83.1 Abnormal level of hormones	0.005	0.995	0.000
R83.0 Abnormal level of enzymes	0.005	0.995	0.000
R89.9 Unspecified abnormal finding	0.005	0.995	0.000
R89.8 Other abnormal findings	0.005	0.995	0.000
R89.7 Abnormal histological findings	0.005	0.995	0.000
R89.6 Abnormal cytological findings	0.005	0.995	0.000
R89.5 Abnormal microbiological findings	0.005	0.995	0.000
R89.4 Abnormal immunological findings	0.005	0.995	0.000
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.005	0.995	0.000
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.005	0.995	0.000
R89.1 Abnormal level of hormones	0.005	0.995	0.000
R89.0 Abnormal level of enzymes	0.005	0.995	0.000
S88 Traumatic amputation of lower leg	0.005	0.995	0.000
S87 Crushing injury of lower leg	0.005	0.995	0.000
S85 Injury of blood vessels at lower leg level	0.005	0.995	0.000
S84 Injury of nerves at lower leg level	0.005	0.995	0.000
S86 Injury of muscle and tendon at lower leg level	0.005	0.995	0.000
S81.9 Open wound of lower leg, part unspecified	0.005	0.995	0.000
H90.5 Sensorineural hearing loss, unspecified	0.005	0.995	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.005	0.995	0.000
K92.0 Haematemesis	0.005	0.995	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.995	0.005
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.005	0.995	0.000
K72.9 Hepatic failure, unspecified	0.005	0.995	0.000
K75.8 Other specified inflammatory liver diseases	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
K73.9 Chronic hepatitis, unspecified	0.004	0.995	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.004	0.995	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.004	0.995	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.004	0.995	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.004	0.995	0.000
G40-G47 Episodic and paroxysmal disorders	0.005	0.995	0.000
K44.1 Diaphragmatic hernia with gangrene	0.004	0.995	0.000
K71.9 Toxic liver disease, unspecified	0.004	0.995	0.000
K71.8 Toxic liver disease with other disorders of liver	0.004	0.995	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.004	0.995	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.004	0.995	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.004	0.995	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.004	0.995	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.004	0.995	0.000
K71.2 Toxic liver disease with acute hepatitis	0.004	0.995	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.004	0.995	0.000
K71.0 Toxic liver disease with cholestasis	0.004	0.995	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.004	0.995	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.004	0.995	0.000
K42.0 Umbilical hernia with obstruction, without gangrene	0.004	0.995	0.000
S89 Other and unspecified injuries of lower leg	0.004	0.995	0.000
S42.20 Fracture of upper end of humerus (closed)	0.005	0.995	0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene	0.004	0.996	0.000
K75.9 Inflammatory liver disease, unspecified	0.004	0.996	0.000
S81.7 Multiple open wounds of lower leg	0.004	0.996	0.000
K70 Alcoholic liver disease	0.004	0.996	0.000
K72.1 Chronic hepatic failure	0.004	0.996	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.004	0.996	0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene	0.004	0.996	0.000
K40.4 Unilateral or unspecified inguinal hernia, with gangrene	0.004	0.996	0.000
K40.1 Bilateral inguinal hernia, with gangrene	0.004	0.996	0.000
K40.0 Bilateral inguinal hernia, with obstruction, without gangrene	0.004	0.996	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.004	0.996	0.000
K75.2 Nonspecific reactive hepatitis	0.004	0.996	0.000
K75.1 Phlebitis of portal vein	0.004	0.996	0.000
H90.3 Sensorineural hearing loss, bilateral	0.004	0.996	0.000
G47.8 Other sleep disorders	0.004	0.996	0.000
G47.4 Narcolepsy and cataplexy	0.004	0.996	0.000
G47.2 Disorders of the sleep-wake schedule	0.004	0.996	0.000
S80 Superficial injury of lower leg	0.004	0.996	0.000
G40.8 Other epilepsy	0.004	0.996	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
K75.0 Abscess of liver	0.004	0.996	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.996	0.004
G44 Other headache syndromes	0.004	0.996	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.004	0.996	0.000
G40.5 Special epileptic syndromes	0.004	0.996	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.004	0.996	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.004	0.996	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.004	0.996	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.004	0.996	0.000
K40.3 Unilateral or unspecified inguinal hernia, with obstruction, without gangrene	0.004	0.996	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.003	0.996	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.004	0.996	0.000
K72.0 Acute and subacute hepatic failure	0.004	0.996	0.000
S84.9 Injury of unspecified nerve at lower leg level	0.004	0.996	0.000
S84.8 Injury of other nerves at lower leg level	0.004	0.996	0.000
S84.7 Injury of multiple nerves at lower leg level	0.004	0.996	0.000
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.004	0.996	0.000
S84.1 Injury of peroneal nerve at lower leg level	0.004	0.996	0.000
S84.0 Injury of tibial nerve at lower leg level	0.004	0.996	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.004	0.996	0.000
S85.8 Injury of other blood vessels at lower leg level	0.004	0.996	0.000
S85.7 Injury of multiple blood vessels at lower leg level	0.004	0.996	0.000
S85.5 Injury of popliteal vein	0.004	0.996	0.000
S85.4 Injury of lesser saphenous vein at lower leg level	0.004	0.996	0.000
S85.3 Injury of greater saphenous vein at lower leg level	0.004	0.996	0.000
S85.2 Injury of peroneal artery	0.004	0.996	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.004	0.996	0.000
S85.0 Injury of popliteal artery	0.004	0.996	0.000
S87.8 Crushing injury of other and unspecified parts of lower leg	0.004	0.996	0.000
S87.0 Crushing injury of knee	0.004	0.996	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.004	0.996	0.000
S88.1 Traumatic amputation at level between knee and ankle	0.004	0.996	0.000
S88.0 Traumatic amputation at knee level	0.004	0.996	0.000
S80.8 Other superficial injuries of lower leg	0.004	0.996	0.000
S86.0 Injury of Achilles tendon	0.004	0.996	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.004	0.996	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.004	0.996	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.004	0.996	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.004	0.996	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.004	0.996	0.000
K70.4 Alcoholic hepatic failure	0.004	0.996	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.004	0.996	0.000
G44.2 Tension-type headache	0.004	0.996	0.000
H65.3 Chronic mucoid otitis media	0.004	0.996	0.000
S81.8 Open wound of other parts of lower leg	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations