TreeWAS – Variant ID: rs12054895

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M54.99 Dorsalgia, unspecified (Site unspecified)	0.000	0.888	0.112
E83.4 Disorders of magnesium metabolism	0.000	0.951	0.049
E83.1 Disorders of iron metabolism	0.000	0.951	0.049
E83 Disorders of mineral metabolism	0.000	0.952	0.048
E83.3 Disorders of phosphorus metabolism	0.000	0.953	0.047
E83.8 Other disorders of mineral metabolism	0.000	0.965	0.035
E83.2 Disorders of zinc metabolism	0.000	0.965	0.035
E83.0 Disorders of copper metabolism	0.000	0.965	0.035
H05.2 Exophthalmic conditions	0.032	0.968	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.968	0.032
E83.5 Disorders of calcium metabolism	0.000	0.969	0.031
D37.7 Other digestive organs	0.000	0.975	0.025
H05 Disorders of orbit	0.023	0.977	0.000
H05.0 Acute inflammation of orbit	0.020	0.980	0.000
H05.1 Chronic inflammatory disorders of orbit	0.018	0.982	0.000
H05.4 Enophthalmos	0.018	0.982	0.000
H05.8 Other disorders of orbit	0.017	0.983	0.000
H05.9 Disorder of orbit, unspecified	0.017	0.983	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.017	0.983	0.000
H05.3 Deformity of orbit	0.017	0.983	0.000
M54.9 Dorsalgia, unspecified	0.000	0.984	0.016
M54.97 Dorsalgia, unspecified (Lumbosacral region)	0.000	0.988	0.012
M54.93 Dorsalgia, unspecified (Cervicothoracic region)	0.000	0.988	0.012
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)	0.000	0.988	0.012
M54.95 Dorsalgia, unspecified (Thoracolumbar region)	0.000	0.989	0.011
M54.94 Dorsalgia, unspecified (Thoracic region)	0.000	0.989	0.011
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.989	0.011
M54.92 Dorsalgia, unspecified (Cervical region)	0.000	0.989	0.010
M75.5 Bursitis of shoulder	0.010	0.990	0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)	0.000	0.990	0.010
L05.0 Pilonidal cyst with abscess	0.010	0.990	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.009	0.991	0.000
H74 Other disorders of middle ear and mastoid	0.008	0.992	0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)	0.000	0.992	0.008
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.992	0.008
H65-H75 Diseases of middle ear and mastoid	0.007	0.993	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.007	0.993	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.007	0.993	0.000
H74.4 Polyp of middle ear	0.007	0.993	0.000
H72 Perforation of tympanic membrane	0.007	0.993	0.000
H72.0 Central perforation of tympanic membrane	0.007	0.993	0.000
H65.4 Other chronic nonsuppurative otitis media	0.007	0.993	0.000
H61.8 Other specified disorders of external ear	0.006	0.994	0.000
I49.8 Other specified cardiac arrhythmias	0.000	0.994	0.006
H65 Nonsuppurative otitis media	0.006	0.994	0.000
H69 Other disorders of Eustachian tube	0.006	0.994	0.000
H74.0 Tympanosclerosis	0.006	0.994	0.000
H71 Cholesteatoma of middle ear	0.006	0.994	0.000
H68 Eustachian salpingitis and obstruction	0.006	0.994	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.000	0.994	0.006
H69.8 Other specified disorders of Eustachian tube	0.006	0.994	0.000
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
L81.9 Disorder of pigmentation, unspecified	0.006	0.994	0.000
S80.9 Superficial injury of lower leg, unspecified	0.006	0.994	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H67 Otitis media in diseases classified elsewhere	0.005	0.995	0.000
H65.2 Chronic serous otitis media	0.005	0.995	0.000
H65.0 Acute serous otitis media	0.005	0.995	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.005	0.995	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.995	0.005
H61 Other disorders of external ear	0.005	0.995	0.000
H70 Mastoiditis and related conditions	0.005	0.995	0.000
N28.1 Cyst of kidney, acquired	0.000	0.995	0.005
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
Z03.4 Observation for suspected myocardial infarction	0.005	0.995	0.000
H74.1 Adhesive middle ear disease	0.005	0.995	0.000
H68.1 Obstruction of Eustachian tube	0.005	0.995	0.000
L05 Pilonidal cyst	0.005	0.995	0.000
H69.0 Patulous Eustachian tube	0.005	0.995	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.005	0.995	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.000	0.995	0.004
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.995	0.005
H65.1 Other acute nonsuppurative otitis media	0.004	0.995	0.000
H66 Suppurative and unspecified otitis media	0.004	0.996	0.000
H68.0 Eustachian salpingitis	0.004	0.996	0.000
H69.9 Eustachian tube disorder, unspecified	0.004	0.996	0.000
H61.0 Perichondritis of external ear	0.004	0.996	0.000
H61.9 Disorder of external ear, unspecified	0.004	0.996	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.000	0.996	0.004
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.996	0.004
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.000	0.996	0.004
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.000	0.996	0.004
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.996	0.004
H73 Other disorders of tympanic membrane	0.004	0.996	0.000
H70.9 Mastoiditis, unspecified	0.004	0.996	0.000
Z92.3 Personal history of irradiation	0.000	0.996	0.004
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.996	0.004
H67.8 Otitis media in other diseases classified elsewhere	0.004	0.996	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.004	0.996	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.004	0.996	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.004	0.996	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.004	0.996	0.000
H60-H62 Diseases of external ear	0.004	0.996	0.000
H61.3 Acquired stenosis of external ear canal	0.004	0.996	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.000	0.996	0.004
K14.8 Other diseases of tongue	0.000	0.996	0.004
L81.8 Other specified disorders of pigmentation	0.004	0.996	0.000
H70.2 Petrositis	0.004	0.996	0.000
H70.0 Acute mastoiditis	0.004	0.996	0.000
H66.0 Acute suppurative otitis media	0.004	0.996	0.000
H61.1 Non-infective disorders of pinna	0.004	0.996	0.000
H70.1 Chronic mastoiditis	0.004	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.004	0.996	0.000
L81 Other disorders of pigmentation	0.004	0.996	0.000
M22.8 Other disorders of patella	0.000	0.996	0.004
L81.2 Freckles	0.004	0.996	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.003	0.996	0.000
H70.8 Other mastoiditis and related conditions	0.003	0.996	0.000
H60.8 Other otitis externa	0.003	0.997	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.003	0.997	0.000
H73.1 Chronic myringitis	0.003	0.997	0.000
H73.0 Acute myringitis	0.003	0.997	0.000
E85.9 Amyloidosis, unspecified	0.000	0.997	0.003
L05.9 Pilonidal cyst without abscess	0.003	0.997	0.000
H66.9 Otitis media, unspecified	0.003	0.997	0.000
K51.8 Other ulcerative colitis	0.003	0.997	0.000
H60 Otitis externa	0.003	0.997	0.000
G35 Multiple sclerosis	0.003	0.997	0.000
E85 Amyloidosis	0.000	0.997	0.003
H73.9 Disorder of tympanic membrane, unspecified	0.003	0.997	0.000
E85.4 Organ-limited amyloidosis	0.000	0.997	0.003
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.003	0.997	0.000
Chapter VIII Diseases of the ear and mastoid process	0.003	0.997	0.000
I30.9 Acute pericarditis, unspecified	0.003	0.997	0.000
E85.3 Secondary systemic amyloidosis	0.000	0.997	0.003
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.997	0.003
L81.7 Pigmented purpuric dermatosis	0.003	0.997	0.000
L81.6 Other disorders of diminished melanin formation	0.003	0.997	0.000
L81.5 Leukoderma, not elsewhere classified	0.003	0.997	0.000
L81.3 Cafe au lait spots	0.003	0.997	0.000
L81.1 Chloasma	0.003	0.997	0.000
L81.0 Postinflammatory hyperpigmentation	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.003	0.997	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.003	0.997	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H62.2 Otitis externa in mycoses	0.003	0.997	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.003	0.997	0.000
K51.5 Mucosal proctocolitis	0.003	0.997	0.000
H60.1 Cellulitis of external ear	0.003	0.997	0.000
G93.4 Encephalopathy, unspecified	0.000	0.997	0.003
H65.9 Nonsuppurative otitis media, unspecified	0.003	0.997	0.000
H65.3 Chronic mucoid otitis media	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.000	0.997	0.003
T93.1 Sequelae of fracture of femur	0.000	0.997	0.003
Z43.2 Attention to ileostomy	0.000	0.997	0.003
H60.2 Malignant otitis externa	0.003	0.997	0.000
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.997	0.003
H61.2 Impacted cerumen	0.003	0.997	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.997	0.002
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.997	0.002
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.997	0.002
K51.2 Ulcerative (chronic) proctitis	0.003	0.997	0.000
R94.7 Abnormal results of other endocrine function studies	0.003	0.997	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.997	0.002
M05 Seropositive rheumatoid arthritis	0.000	0.997	0.002
J38.1 Polyp of vocal cord and larynx	0.000	0.998	0.002
H60.5 Acute otitis externa, non-infective	0.002	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
T93 Sequelae of injuries of lower limb	0.000	0.998	0.002
S60.8 Other superficial injuries of wrist and hand	0.002	0.998	0.000
K51 Ulcerative colitis	0.002	0.998	0.000
E70-E90 Metabolic disorders	0.000	0.998	0.002
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.998	0.002
H60.4 Cholesteatoma of external ear	0.002	0.998	0.000
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
H60.3 Other infective otitis externa	0.002	0.998	0.000
D26.1 Corpus uteri	0.000	0.998	0.002
H66.3 Other chronic suppurative otitis media	0.002	0.998	0.000
H60.0 Abscess of external ear	0.002	0.998	0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.998	0.002
K51.0 Ulcerative (chronic) enterocolitis	0.002	0.998	0.000
E74 Other disorders of carbohydrate metabolism	0.000	0.998	0.002
M23.49 Loose body in knee-Unspec lig/men	0.000	0.998	0.002
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
S43.0 Dislocation of shoulder joint	0.000	0.998	0.002
E85.8 Other amyloidosis	0.000	0.998	0.002
H44.2 Degenerative myopia	0.000	0.998	0.002
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.998	0.002
R41.3 Other amnesia	0.000	0.998	0.002
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
G93.6 Cerebral oedema	0.000	0.998	0.002
K51.1 Ulcerative (chronic) ileocolitis	0.002	0.998	0.000
E78.2 Mixed hyperlipidaemia	0.000	0.998	0.002
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.998	0.002
K51.3 Ulcerative (chronic) rectosigmoiditis	0.002	0.998	0.000
M05.8 Other seropositive rheumatoid arthritis	0.000	0.998	0.002
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.000	0.998	0.002
M05.2 Rheumatoid vasculitis	0.000	0.998	0.002
M05.1 Rheumatoid lung disease	0.000	0.998	0.002
M05.0 Felty's syndrome	0.000	0.998	0.002
M94.26 Chondromalacia (Lower leg)	0.000	0.998	0.002
E78.4 Other hyperlipidaemia	0.000	0.998	0.002
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.998	0.002
C16.0 Cardia	0.002	0.998	0.000
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.998	0.002
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.998	0.002
E77 Disorders of glycoprotein metabolism	0.000	0.998	0.002
E76 Disorders of glycosaminoglycan metabolism	0.000	0.998	0.002
E72 Other disorders of amino-acid metabolism	0.000	0.998	0.002
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.998	0.002
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
E70 Disorders of aromatic amino-acid metabolism	0.000	0.998	0.002
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.998	0.002
E84 Cystic fibrosis	0.000	0.998	0.002
E79 Disorders of purine and pyrimidine metabolism	0.000	0.998	0.002
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.000	0.998	0.002
I60 Subarachnoid haemorrhage	0.000	0.998	0.002
Y43.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.998	0.002
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.998	0.002
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.998	0.002
E74.2 Disorders of galactose metabolism	0.000	0.998	0.002
E74.1 Disorders of fructose metabolism	0.000	0.998	0.002
E74.0 Glycogen storage disease	0.000	0.998	0.002
R94.8 Abnormal results of function studies of other organs and systems	0.002	0.998	0.000
C16.5 Lesser curvature of stomach, unspecified	0.002	0.998	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.998	0.002
M31.3 Wegener's granulomatosis	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
C16.2 Body of stomach	0.002	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.998	0.002
D37.4 Colon	0.000	0.998	0.002
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.002	0.998	0.000
L04.9 Acute lymphadenitis, unspecified	0.002	0.998	0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract	0.002	0.998	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.000	0.998	0.002
R94.3 Abnormal results of cardiovascular function studies	0.002	0.998	0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
E75.5 Other lipid storage disorders	0.000	0.998	0.002
L04 Acute lymphadenitis	0.002	0.998	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
O44.1 Placenta praevia with haemorrhage	0.002	0.998	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.002	0.998	0.000
T93.0 Sequelae of open wound of lower limb	0.000	0.998	0.002
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
M05.09 Felty's syndrome (Site unspecified)	0.000	0.998	0.001
M05.08 Felty's syndrome (Other)	0.000	0.998	0.001
M05.07 Felty's syndrome (Ankle and foot)	0.000	0.998	0.001
M05.06 Felty's syndrome (Lower leg)	0.000	0.998	0.001
M05.05 Felty's syndrome (Pelvic region and thigh)	0.000	0.998	0.001
M05.04 Felty's syndrome (Hand)	0.000	0.998	0.001
M05.03 Felty's syndrome (Forearm)	0.000	0.998	0.001
M05.02 Felty's syndrome (Upper arm)	0.000	0.998	0.001
M05.01 Felty's syndrome (Shoulder region)	0.000	0.998	0.001
M05.00 Felty's syndrome (Multiple sites)	0.000	0.998	0.001
M05.19 Rheumatoid lung disease (Site unspecified)	0.000	0.998	0.001
M05.18 Rheumatoid lung disease (Other)	0.000	0.998	0.001
M05.17 Rheumatoid lung disease (Ankle and foot)	0.000	0.998	0.001
M05.16 Rheumatoid lung disease (Lower leg)	0.000	0.998	0.001
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.000	0.998	0.001
M05.14 Rheumatoid lung disease (Hand)	0.000	0.998	0.001
M05.13 Rheumatoid lung disease (Forearm)	0.000	0.998	0.001
M05.12 Rheumatoid lung disease (Upper arm)	0.000	0.998	0.001
M05.11 Rheumatoid lung disease (Shoulder region)	0.000	0.998	0.001
M05.10 Rheumatoid lung disease (Multiple sites)	0.000	0.998	0.001
M05.29 Rheumatoid vasculitis (Site unspecified)	0.000	0.998	0.001
M05.28 Rheumatoid vasculitis (Other)	0.000	0.998	0.001
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.000	0.998	0.001
M05.26 Rheumatoid vasculitis (Lower leg)	0.000	0.998	0.001
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.000	0.998	0.001
M05.24 Rheumatoid vasculitis (Hand)	0.000	0.998	0.001
M05.23 Rheumatoid vasculitis (Forearm)	0.000	0.998	0.001
M05.22 Rheumatoid vasculitis (Upper arm)	0.000	0.998	0.001
M05.21 Rheumatoid vasculitis (Shoulder region)	0.000	0.998	0.001
M05.20 Rheumatoid vasculitis (Multiple sites)	0.000	0.998	0.001
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.000	0.998	0.001
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.000	0.998	0.001
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.000	0.998	0.001
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.000	0.998	0.001
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.000	0.998	0.001
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.000	0.998	0.001
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.000	0.998	0.001
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.000	0.998	0.001
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.000	0.998	0.001
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.000	0.998	0.001
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.000	0.998	0.001
M05.88 Other seropositive rheumatoid arthritis (Other)	0.000	0.998	0.001
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.000	0.998	0.001
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.000	0.998	0.001
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.000	0.998	0.001
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.000	0.998	0.001
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.000	0.998	0.001
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.000	0.998	0.001
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.000	0.998	0.001
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.000	0.998	0.001
L04.0 Acute lymphadenitis of face, head and neck	0.002	0.998	0.000
E75.6 Lipid storage disorder, unspecified	0.000	0.998	0.002
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.998	0.002
E75.3 Sphingolipidosis, unspecified	0.000	0.998	0.002
E75.2 Other sphingolipidosis	0.000	0.998	0.002
E75.1 Other gangliosidosis	0.000	0.998	0.002
E75.0 GM2 gangliosidosis	0.000	0.998	0.002
C16 Malignant neoplasm of stomach	0.002	0.998	0.000
H95.1 Other disorders following mastoidectomy	0.002	0.998	0.000
O43.1 Malformation of placenta	0.000	0.998	0.002
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.998	0.001
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.998	0.001
E70.2 Disorders of tyrosine metabolism	0.000	0.998	0.001
E70.1 Other hyperphenylalaninaemias	0.000	0.998	0.001
E70.0 Classical phenylketonuria	0.000	0.998	0.001
E71.3 Disorders of fatty-acid metabolism	0.000	0.998	0.001
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.998	0.001
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.998	0.001
E71.0 Maple-syrup-urine disease	0.000	0.998	0.001
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.998	0.001
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.998	0.001
E72.5 Disorders of glycine metabolism	0.000	0.998	0.001
E72.4 Disorders of ornithine metabolism	0.000	0.998	0.001
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.998	0.001
E72.2 Disorders of urea cycle metabolism	0.000	0.998	0.001
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.998	0.001
E72.0 Disorders of amino-acid transport	0.000	0.998	0.001
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.998	0.001
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.998	0.001
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.998	0.001
E76.2 Other mucopolysaccharidoses	0.000	0.998	0.001
E76.1 Mucopolysaccharidosis, type II	0.000	0.998	0.001
E76.0 Mucopolysaccharidosis, type I	0.000	0.998	0.001
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.998	0.001
E77.8 Other disorders of glycoprotein metabolism	0.000	0.998	0.001
E77.1 Defects in glycoprotein degradation	0.000	0.998	0.001
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.998	0.001
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.998	0.002
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.998	0.002
E70.3 Albinism	0.000	0.998	0.001
E84.8 Cystic fibrosis with other manifestations	0.000	0.998	0.001
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.998	0.001
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.998	0.001
C16.8 Overlapping lesion of stomach	0.002	0.998	0.000
C16.3 Pyloric antrum	0.002	0.998	0.000
D37.2 Small intestine	0.000	0.998	0.002
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.998	0.001
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.998	0.001
E79.1 Lesch-Nyhan syndrome	0.000	0.998	0.001
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.002	0.998	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.998	0.002
D37.3 Appendix	0.000	0.998	0.002
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.998	0.002
E84.9 Cystic fibrosis, unspecified	0.000	0.998	0.001
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
R41.2 Retrograde amnesia	0.000	0.998	0.002
E73 Lactose intolerance	0.000	0.998	0.001
M86.96 Osteomyelitis, unspecified (Lower leg)	0.002	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.002	0.998	0.000
H55 Nystagmus and other irregular eye movements	0.000	0.998	0.002
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.998	0.001
E80.6 Other disorders of bilirubin metabolism	0.000	0.998	0.002
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.000	0.998	0.002
T91.3 Sequelae of injury of spinal cord	0.002	0.998	0.000
Z09.2 Follow-up examination after chemotherapy for other conditions	0.000	0.998	0.002
G35-G37 Demyelinating diseases of the central nervous system	0.002	0.998	0.000
I60.8 Other subarachnoid haemorrhage	0.000	0.998	0.002
N64.8 Other specified disorders of breast	0.002	0.998	0.000
O21.0 Mild hyperemesis gravidarum	0.002	0.998	0.000
A49.9 Bacterial infection, unspecified	0.002	0.998	0.000
S60.0 Contusion of finger(s) without damage to nail	0.002	0.998	0.000
S61.1 Open wound of finger(s) with damage to nail	0.000	0.998	0.002
M86.98 Osteomyelitis, unspecified (Other)	0.001	0.998	0.000
K82.4 Cholesterolosis of gallbladder	0.002	0.998	0.000
N28.0 Ischaemia and infarction of kidney	0.000	0.998	0.002
S43.6 Sprain and strain of sternoclavicular joint	0.000	0.998	0.001
S43.5 Sprain and strain of acromioclavicular joint	0.000	0.998	0.001
S43.4 Sprain and strain of shoulder joint	0.000	0.998	0.001
S43.3 Dislocation of other and unspecified parts of shoulder girdle	0.000	0.998	0.001
S43.2 Dislocation of sternoclavicular joint	0.000	0.998	0.001
L04.8 Acute lymphadenitis of other sites	0.001	0.998	0.000
L04.3 Acute lymphadenitis of lower limb	0.001	0.998	0.000
L04.2 Acute lymphadenitis of upper limb	0.001	0.998	0.000
L04.1 Acute lymphadenitis of trunk	0.001	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.000	0.998	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.002	0.998	0.000
Y40.0 Penicillins	0.000	0.998	0.002
L00-L08 Infections of the skin and subcutaneous tissue	0.002	0.998	0.000
C16.4 Pylorus	0.001	0.998	0.000
D37.9 Digestive organ, unspecified	0.000	0.998	0.001
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.998	0.001
O43.8 Other placental disorders	0.001	0.998	0.000
G36 Other acute disseminated demyelination	0.001	0.998	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.998	0.002
L01 Impetigo	0.001	0.998	0.000
S60 Superficial injury of wrist and hand	0.002	0.998	0.000
E80.2 Other porphyria	0.000	0.998	0.001
F81.9 Developmental disorder of scholastic skills, unspecified	0.001	0.998	0.000
H43.3 Other vitreous opacities	0.001	0.998	0.000
L01.0 Impetigo [any organism] [any site]	0.001	0.998	0.000
R19.5 Other fecal abnormalities	0.002	0.998	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.998	0.002
L02 Cutaneous abscess, furuncle and carbuncle	0.002	0.998	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.001	0.999	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.001	0.999	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.001	0.999	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.001	0.999	0.000
S32.50 Fracture of pubis (closed)	0.000	0.999	0.001
C16.1 Fundus of stomach	0.001	0.999	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.999	0.001
E80.5 Crigler-Najjar syndrome	0.000	0.999	0.001
E80.3 Defects of catalase and peroxydase	0.000	0.999	0.001
E80.0 Hereditary erythropoietic porphyria	0.000	0.999	0.001
F20.9 Schizophrenia, unspecified	0.001	0.999	0.000
G71.1 Myotonic disorders	0.000	0.999	0.001
E73.8 Other lactose intolerance	0.000	0.999	0.001
E73.1 Secondary lactase deficiency	0.000	0.999	0.001
E73.0 Congenital lactase deficiency	0.000	0.999	0.001
J92.9 Pleural plaque without asbestos	0.001	0.999	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.999	0.001
G36.0 Neuromyelitis optica [Devic]	0.001	0.999	0.000
S32.3 Fracture of ilium	0.000	0.999	0.001
E88 Other metabolic disorders	0.000	0.999	0.001
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S62.60 Fracture of other finger (closed)	0.000	0.999	0.001
R94.0 Abnormal results of function studies of central nervous system	0.001	0.999	0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle	0.000	0.999	0.001
M47.22 Other spondylosis with radiculopathy (Cervical region)	0.001	0.999	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.001	0.999	0.000
G93.9 Disorder of brain, unspecified	0.000	0.999	0.001
S60.2 Contusion of other parts of wrist and hand	0.001	0.999	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.001	0.999	0.000
R94 Abnormal results of function studies	0.001	0.999	0.000
G71.0 Muscular dystrophy	0.000	0.999	0.001
H59.8 Other postprocedural disorders of eye and adnexa	0.000	0.999	0.001
K42.9 Umbilical hernia without obstruction or gangrene	0.001	0.999	0.000
R25.1 Tremor, unspecified	0.000	0.999	0.001
L00 Staphylococcal scalded skin syndrome	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
G36.9 Acute disseminated demyelination, unspecified	0.001	0.999	0.000
G36.8 Other specified acute disseminated demyelination	0.001	0.999	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.001	0.999	0.000
S60.7 Multiple superficial injuries of wrist and hand	0.001	0.999	0.000
G37 Other demyelinating diseases of central nervous system	0.001	0.999	0.000
E80.1 Porphyria cutanea tarda	0.000	0.999	0.001
L01.1 Impetiginisation of other dermatoses	0.001	0.999	0.000
S60.1 Contusion of finger(s) with damage to nail	0.001	0.999	0.000
X50.4 Street and highway	0.001	0.999	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.001	0.999	0.000
I30 Acute pericarditis	0.001	0.999	0.000
S42.70 Multiple fractures of clavicle, scapula and humerus (closed)	0.000	0.999	0.001
C18.9 Colon, unspecified	0.000	0.999	0.001
E78.6 Lipoprotein deficiency	0.000	0.999	0.001
E88.8 Other specified metabolic disorders	0.000	0.999	0.001
K51.4 Pseudopolyposis of colon	0.001	0.999	0.000
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.999	0.001
Z46.8 Fitting and adjustment of other specified devices	0.000	0.999	0.001
Z99.1 Dependence on respirator	0.000	0.999	0.001
G37.9 Demyelinating disease of central nervous system, unspecified	0.001	0.999	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.001	0.999	0.000
R94.6 Abnormal results of thyroid function studies	0.001	0.999	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.001	0.999	0.000
S32.31 Fracture of ilium (open)	0.000	0.999	0.001
C77.4 Inguinal and lower limb lymph nodes	0.000	0.999	0.001
E88.9 Metabolic disorder, unspecified	0.000	0.999	0.001
E88.3 Tumour lysis syndrome	0.000	0.999	0.001
N27.0 Small kidney, unilateral	0.000	0.999	0.001
R41.0 Disorientation, unspecified	0.000	0.999	0.001
Y42.7 Androgens and anabolic congeners	0.001	0.999	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.001	0.999	0.000
M71.38 Other bursal cyst (Other)	0.001	0.999	0.000
E78.3 Hyperchylomicronaemia	0.000	0.999	0.001
K59.9 Functional intestinal disorder, unspecified	0.001	0.999	0.000
Z29.2 Other prophylactic chemotherapy	0.001	0.999	0.000
Z34.0 Supervision of normal first pregnancy	0.000	0.999	0.001
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.001	0.999	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.999	0.001
F31.8 Other bipolar affective disorders	0.001	0.999	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.001	0.999	0.000
R94.1 Abnormal results of function studies of peripheral nervous system and special senses	0.001	0.999	0.000
S32.5 Fracture of pubis	0.000	0.999	0.001
W29.9 Unspecified place	0.000	0.999	0.001
Y42.4 Oral contraceptives	0.001	0.999	0.000
Z90.0 Acquired absence of part of head and neck	0.000	0.999	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.001	0.999	0.000
D37.5 Rectum	0.000	0.999	0.001
G37.5 Concentric sclerosis [Balo]	0.001	0.999	0.000
G37.4 Subacute necrotising myelitis	0.001	0.999	0.000
G37.2 Central pontine myelinolysis	0.001	0.999	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.999	0.000
G37.0 Diffuse sclerosis	0.001	0.999	0.000
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.001	0.999	0.000
L02.0 Cutaneous abscess, furuncle and carbuncle of face	0.001	0.999	0.000
M94.2 Chondromalacia	0.000	0.999	0.001
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.999	0.001
R41 Other symptoms and signs involving cognitive functions and awareness	0.000	0.999	0.001
S32.40 Fracture of acetabulum (closed)	0.000	0.999	0.001
A41.1 Septicaemia due to other specified staphylococcus	0.001	0.999	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.999	0.001
I30.8 Other forms of acute pericarditis	0.001	0.999	0.000
I30.0 Acute nonspecific idiopathic pericarditis	0.001	0.999	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.001	0.999	0.000
N81.3 Complete uterovaginal prolapse	0.001	0.999	0.000
C49.0 Connective and soft tissue of head, face and neck	0.000	0.999	0.001
D22.0 Melanocytic naevi of lip	0.001	0.999	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.001	0.999	0.000
L02.1 Cutaneous abscess, furuncle and carbuncle of neck	0.001	0.999	0.000
M93.9 Osteochondropathy, unspecified	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations