TreeWAS – Variant ID: rs12108452

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H25 Senile cataract	1.000	0.000	0.000
H33 Retinal detachments and breaks	1.000	0.000	0.000
H25-H28 Disorders of lens	1.000	0.000	0.000
H30-H36 Disorders of choroid and retina	1.000	0.000	0.000
H33.0 Retinal detachment with retinal break	1.000	0.000	0.000
Chapter VII Diseases of the eye and adnexa	1.000	0.000	0.000
H25.1 Senile nuclear cataract	1.000	0.000	0.000
H33.2 Serous retinal detachment	0.993	0.007	0.000
H40-H42 Glaucoma	0.993	0.007	0.000
H40.9 Glaucoma, unspecified	0.990	0.010	0.000
H40 Glaucoma	0.987	0.013	0.000
H25.0 Senile incipient cataract	0.984	0.016	0.000
H36 Retinal disorders in diseases classified elsewhere	0.982	0.018	0.000
H26 Other cataract	0.977	0.023	0.000
H26.4 After-cataract	0.970	0.030	0.000
H43-H45 Disorders of vitreous body and globe	0.970	0.030	0.000
H36.0 Diabetic retinopathy	0.969	0.031	0.000
H43 Disorders of vitreous body	0.947	0.053	0.000
H25.9 Senile cataract, unspecified	0.942	0.058	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.937	0.063	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.936	0.064	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.934	0.066	0.000
H43.3 Other vitreous opacities	0.888	0.112	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.873	0.127	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.872	0.128	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.867	0.133	0.000
H43.8 Other disorders of vitreous body	0.857	0.143	0.000
T39.0 Salicylates	0.850	0.150	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.849	0.151	0.000
H30 Chorioretinal inflammation	0.823	0.177	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.807	0.193	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.806	0.194	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.802	0.198	0.000
H33.5 Other retinal detachments	0.799	0.201	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.799	0.201	0.000
H26.3 Drug-induced cataract	0.792	0.208	0.000
H40.4 Glaucoma secondary to eye inflammation	0.785	0.215	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.782	0.218	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.779	0.221	0.000
H27 Other disorders of lens	0.775	0.225	0.000
T36 Poisoning by systemic antibiotics	0.773	0.227	0.000
H26.0 Infantile, juvenile and presenile cataract	0.770	0.230	0.000
T50.4 Drugs affecting uric acid metabolism	0.753	0.246	0.000
H25.8 Other senile cataract	0.752	0.248	0.000
H33.4 Traction detachment of retina	0.749	0.251	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.748	0.252	0.000
H43.2 Crystalline deposits in vitreous body	0.748	0.252	0.000
H43.9 Disorder of vitreous body, unspecified	0.739	0.261	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.726	0.274	0.000
H26.1 Traumatic cataract	0.718	0.282	0.000
H25.2 Senile cataract, morgagnian type	0.717	0.283	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.717	0.283	0.000
H44 Disorders of globe	0.713	0.287	0.000
H42 Glaucoma in diseases classified elsewhere	0.712	0.288	0.000
H40.6 Glaucoma secondary to drugs	0.708	0.292	0.000
T50.8 Diagnostic agents	0.706	0.294	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.704	0.296	0.000
H33.1 Retinoschisis and retinal cysts	0.703	0.297	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.701	0.298	0.000
H30.9 Chorioretinal inflammation, unspecified	0.697	0.303	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.695	0.305	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.694	0.306	0.000
T46.1 Calcium-channel blockers	0.692	0.308	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.688	0.312	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.681	0.319	0.000
H43.0 Vitreous prolapse	0.679	0.321	0.000
H40.3 Glaucoma secondary to eye trauma	0.673	0.327	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.672	0.328	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.672	0.328	0.000
T50.7 Analeptics and opioid receptor antagonists	0.671	0.329	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.671	0.329	0.000
T50.5 Appetite depressants	0.671	0.329	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.671	0.329	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.671	0.329	0.000
T50.1 Loop [high-ceiling] diuretics	0.671	0.329	0.000
T50.0 Mineralocorticoids and their antagonists	0.671	0.329	0.000
H28.0 Diabetic cataract	0.667	0.333	0.000
T36.0 Penicillins	0.656	0.344	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.653	0.347	0.000
H40.1 Primary open-angle glaucoma	0.650	0.350	0.000
H40.0 Glaucoma suspect	0.649	0.351	0.000
T45.0 Antiallergic and antiemetic drugs	0.649	0.351	0.000
H27.1 Dislocation of lens	0.641	0.359	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.636	0.363	0.000
T38.1 Thyroid hormones and substitutes	0.627	0.373	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.626	0.374	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.626	0.374	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.626	0.374	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.626	0.374	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.626	0.374	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.626	0.374	0.000
T44.0 Anticholinesterase agents	0.626	0.374	0.000
T39.4 Antirheumatics, not elsewhere classified	0.625	0.375	0.000
T39.2 Pyrazolone derivatives	0.625	0.375	0.000
T47.6 Antidiarrhoeal drugs	0.623	0.377	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.621	0.379	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.621	0.379	0.000
T46.7 Peripheral vasodilators	0.621	0.379	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.621	0.379	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.621	0.379	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.621	0.379	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.621	0.379	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.618	0.382	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.617	0.383	0.000
H44.2 Degenerative myopia	0.615	0.385	0.000
T38.9 Other and unspecified hormone antagonists	0.609	0.391	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.609	0.391	0.000
T38.7 Androgens and anabolic congeners	0.609	0.391	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.609	0.391	0.000
T38.5 Other oestrogens and progestogens	0.609	0.391	0.000
T38.4 Oral contraceptives	0.609	0.391	0.000
T38.2 Antithyroid drugs	0.609	0.391	0.000
T38.0 Glucocorticoids and synthetic analogues	0.609	0.391	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.609	0.391	0.000
H27.0 Aphakia	0.607	0.393	0.000
T47.4 Other laxatives	0.597	0.403	0.000
H30.8 Other chorioretinal inflammations	0.590	0.410	0.000
H30.2 Posterior cyclitis	0.590	0.410	0.000
H30.1 Disseminated chorioretinal inflammation	0.590	0.410	0.000
H30.0 Focal chorioretinal inflammation	0.590	0.410	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.587	0.413	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.586	0.414	0.000
H26.2 Complicated cataract	0.585	0.415	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.583	0.417	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.581	0.419	0.000
T43.9 Psychotropic drug, unspecified	0.579	0.421	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.579	0.421	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.579	0.421	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.578	0.422	0.000
H28.2 Cataract in other diseases classified elsewhere	0.578	0.422	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.578	0.422	0.000
T43.6 Psychostimulants with abuse potential	0.574	0.426	0.000
T45.5 Anticoagulants	0.571	0.429	0.000
H33.3 Retinal breaks without detachment	0.564	0.436	0.000
H31 Other disorders of choroid	0.563	0.436	0.000
H55-H59 Other disorders of eye and adnexa	0.560	0.440	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.559	0.441	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.558	0.442	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.558	0.442	0.000
T47.7 Emetics	0.558	0.442	0.000
T47.5 Digestants	0.558	0.442	0.000
T47.3 Saline and osmotic laxatives	0.558	0.442	0.000
T47.2 Stimulant laxatives	0.558	0.442	0.000
T47.0 Histamine H(2)-receptor antagonists	0.558	0.442	0.000
H43.1 Vitreous haemorrhage	0.557	0.443	0.000
H27.9 Disorder of lens, unspecified	0.556	0.444	0.000
T36.9 Systemic antibiotic, unspecified	0.554	0.446	0.000
T36.8 Other systemic antibiotics	0.554	0.446	0.000
T36.7 Antifungal antibiotics, systemically used	0.554	0.446	0.000
T36.6 Rifamycins	0.554	0.446	0.000
T36.5 Aminoglycosides	0.554	0.446	0.000
T36.4 Tetracyclines	0.554	0.446	0.000
T36.3 Macrolides	0.554	0.446	0.000
T36.2 Chloramphenicol group	0.554	0.446	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.554	0.446	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.537	0.463	0.000
T45.8 Other primarily systemic and haematological agents	0.537	0.463	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.537	0.463	0.000
T45.6 Fibrinolysis-affecting drugs	0.537	0.463	0.000
T45.4 Iron and its compounds	0.537	0.463	0.000
T45.3 Enzymes, not elsewhere classified	0.537	0.463	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.533	0.467	0.000
H40.5 Glaucoma secondary to other eye disorders	0.529	0.471	0.000
H44.8 Other disorders of globe	0.524	0.475	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.514	0.486	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
T39.1 4-Aminophenol derivatives	0.511	0.489	0.000
H44.9 Disorder of globe, unspecified	0.511	0.489	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.511	0.489	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.511	0.489	0.000
H44.5 Degenerated conditions of globe	0.511	0.489	0.000
H44.4 Hypotony of eye	0.511	0.489	0.000
H44.3 Other degenerative disorders of globe	0.511	0.489	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.510	0.490	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.510	0.490	0.000
H35 Other retinal disorders	0.507	0.493	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.505	0.495	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.503	0.497	0.000
T48.5 Anti-common-cold drugs	0.503	0.497	0.000
T48.4 Expectorants	0.503	0.497	0.000
T48.3 Antitussives	0.503	0.497	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.503	0.497	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.503	0.497	0.000
T48.0 Oxytocic drugs	0.503	0.497	0.000
T42.0 Hydantoin derivatives	0.503	0.497	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.498	0.501	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.498	0.501	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.498	0.501	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.498	0.502	0.000
H44.1 Other endophthalmitis	0.495	0.505	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.493	0.506	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.488	0.511	0.000
T37.5 Antiviral drugs	0.488	0.511	0.000
T37.4 Anthelminthics	0.488	0.511	0.000
T37.3 Other antiprotozoal drugs	0.488	0.511	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.488	0.511	0.000
T37.1 Antimycobacterial drugs	0.488	0.511	0.000
T37.0 Sulphonamides	0.488	0.511	0.000
H35.2 Other proliferative retinopathy	0.484	0.516	0.000
T41.5 Therapeutic gases	0.482	0.518	0.000
T41.4 Anaesthetic, unspecified	0.482	0.518	0.000
T41.3 Local anaesthetics	0.482	0.518	0.000
T41.2 Other and unspecified general anaesthetics	0.482	0.518	0.000
T41.1 Intravenous anaesthetics	0.482	0.518	0.000
T41.0 Inhaled anaesthetics	0.482	0.518	0.000
T49.9 Topical agent, unspecified	0.482	0.518	0.000
T49.8 Other topical agents	0.482	0.518	0.000
T49.7 Dental drugs, topically applied	0.482	0.518	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.482	0.518	0.000
T49.5 Ophthalmological drugs and preparations	0.482	0.518	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.482	0.518	0.000
T49.3 Emollients, demulcents and protectants	0.482	0.518	0.000
T49.2 Local astringents and local detergents	0.482	0.518	0.000
T49.1 Antipruritics	0.482	0.518	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.482	0.518	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.481	0.519	0.000
H10-H13 Disorders of conjunctiva	0.481	0.519	0.000
T40.4 Other synthetic narcotics	0.470	0.530	0.000
T45.2 Vitamins, not elsewhere classified	0.462	0.538	0.000
H26.9 Cataract, unspecified	0.460	0.540	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.442	0.557	0.000
H55 Nystagmus and other irregular eye movements	0.440	0.560	0.000
H53-H54 Visual disturbances and blindness	0.438	0.562	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.437	0.563	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.431	0.569	0.000
H27.8 Other specified disorders of lens	0.430	0.569	0.000
T42.1 Iminostilbenes	0.422	0.578	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.421	0.579	0.000
T42.3 Barbiturates	0.421	0.579	0.000
T42.2 Succinimides and oxazolidinediones	0.421	0.579	0.000
H31.1 Choroidal degeneration	0.419	0.581	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.417	0.583	0.000
T40.8 Lysergide [LSD]	0.417	0.583	0.000
T40.7 Cannabis (derivatives)	0.417	0.583	0.000
T40.5 Cocaine	0.417	0.583	0.000
T40.3 Methadone	0.417	0.583	0.000
T40.1 Heroin	0.417	0.583	0.000
T40.0 Opium	0.417	0.583	0.000
H26.8 Other specified cataract	0.409	0.591	0.000
H31.9 Disorder of choroid, unspecified	0.404	0.596	0.000
H31.4 Choroidal detachment	0.404	0.596	0.000
H31.2 Hereditary choroidal dystrophy	0.404	0.596	0.000
T40.6 Other and unspecified narcotics	0.401	0.599	0.000
H46 Optic neuritis	0.400	0.600	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.399	0.600	0.000
H34 Retinal vascular occlusions	0.396	0.603	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.396	0.604	0.000
H31.3 Choroidal haemorrhage and rupture	0.392	0.608	0.000
H35.7 Separation of retinal layers	0.385	0.615	0.000
H31.0 Chorioretinal scars	0.382	0.618	0.000
H21 Other disorders of iris and ciliary body	0.380	0.620	0.000
H16 Keratitis	0.374	0.626	0.000
H35.3 Degeneration of macula and posterior pole	0.366	0.634	0.000
H35.1 Retinopathy of prematurity	0.363	0.636	0.000
H40.8 Other glaucoma	0.362	0.637	0.001
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.361	0.639	0.000
T43.2 Other and unspecified antidepressants	0.361	0.639	0.000
H35.8 Other specified retinal disorders	0.353	0.647	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.345	0.655	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.345	0.655	0.000
H17 Corneal scars and opacities	0.340	0.660	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.339	0.661	0.000
H44.0 Purulent endophthalmitis	0.334	0.665	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.331	0.669	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.317	0.682	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.317	0.682	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.317	0.682	0.000
H34.1 Central retinal artery occlusion	0.316	0.684	0.000
H18 Other disorders of cornea	0.315	0.685	0.000
H15 Disorders of sclera	0.314	0.686	0.000
H35.4 Peripheral retinal degeneration	0.312	0.688	0.000
H54 Blindness and low vision	0.310	0.690	0.000
H16.8 Other keratitis	0.306	0.694	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.304	0.695	0.000
H21.0 Hyphaema	0.298	0.702	0.000
H47.3 Other disorders of optic disk	0.295	0.705	0.000
H47.1 Papilloedema, unspecified	0.291	0.709	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.289	0.711	0.000
H16.9 Keratitis, unspecified	0.288	0.711	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.286	0.713	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.286	0.713	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.286	0.713	0.000
H34.0 Transient retinal artery occlusion	0.284	0.715	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.284	0.715	0.000
H47.7 Disorder of visual pathways, unspecified	0.284	0.716	0.000
H47.6 Disorders of visual cortex	0.284	0.716	0.000
H47.5 Disorders of other visual pathways	0.284	0.716	0.000
H47.4 Disorders of optic chiasm	0.284	0.716	0.000
H35.5 Hereditary retinal dystrophy	0.284	0.716	0.000
H31.8 Other specified disorders of choroid	0.280	0.719	0.001
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.279	0.721	0.000
H34.9 Retinal vascular occlusion, unspecified	0.276	0.723	0.000
H16.2 Keratoconjunctivitis	0.275	0.725	0.000
H49 Paralytic strabismus	0.274	0.726	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.272	0.728	0.000
H21.4 Pupillary membranes	0.272	0.728	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.272	0.728	0.000
H21.2 Degeneration of iris and ciliary body	0.272	0.728	0.000
H54.4 Blindness, one eye	0.270	0.730	0.000
H16.4 Corneal neovascularisation	0.268	0.731	0.000
H16.3 Interstitial and deep keratitis	0.268	0.731	0.000
H18.2 Other corneal oedema	0.268	0.732	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.267	0.733	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.264	0.736	0.000
H57 Other disorders of eye and adnexa	0.264	0.736	0.000
H17.8 Other corneal scars and opacities	0.262	0.738	0.000
H10 Conjunctivitis	0.262	0.738	0.000
H51 Other disorders of binocular movement	0.259	0.741	0.000
H18.8 Other specified disorders of cornea	0.259	0.741	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.251	0.749	0.000
H54.2 Low vision, both eyes	0.251	0.749	0.000
H11 Other disorders of conjunctiva	0.250	0.750	0.000
H21.8 Other specified disorders of iris and ciliary body	0.249	0.751	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.248	0.752	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.248	0.752	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.248	0.752	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.247	0.752	0.000
H13.3 Ocular pemphigoid	0.247	0.752	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.247	0.752	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.247	0.752	0.000
H13.0 Filarial infection of conjunctiva	0.247	0.752	0.000
H17.1 Other central corneal opacity	0.244	0.756	0.000
H17.0 Adherent leukoma	0.244	0.756	0.000
H59.0 Vitreous syndrome following cataract surgery	0.243	0.757	0.000
H57.0 Anomalies of pupillary function	0.239	0.761	0.000
H49.1 Fourth [trochlear] nerve palsy	0.237	0.763	0.000
T40.2 Other opioids	0.235	0.765	0.000
H15.1 Episcleritis	0.233	0.767	0.000
H35.0 Background retinopathy and retinal vascular changes	0.231	0.769	0.000
H18.0 Corneal pigmentations and deposits	0.228	0.772	0.000
H18.3 Changes in corneal membranes	0.227	0.773	0.000
H18.7 Other corneal deformities	0.226	0.774	0.000
H15.9 Disorder of sclera, unspecified	0.225	0.774	0.000
H15.0 Scleritis	0.225	0.774	0.000
H35.6 Retinal haemorrhage	0.225	0.775	0.000
H54.5 Low vision, one eye	0.225	0.775	0.000
H54.9 Unspecified visual impairment (binocular)	0.224	0.776	0.000
H16.0 Corneal ulcer	0.223	0.776	0.000
H18.1 Bullous keratopathy	0.223	0.777	0.000
H54.3 Unqualified visual loss, both eyes	0.222	0.778	0.000
H18.9 Disorder of cornea, unspecified	0.222	0.778	0.000
H49.4 Progressive external ophthalmoplegia	0.221	0.779	0.000
H49.9 Paralytic strabismus, unspecified	0.220	0.780	0.000
H11.9 Disorder of conjunctiva, unspecified	0.217	0.783	0.000
H54.6 Unqualified visual loss, one eye	0.215	0.785	0.000
H17.9 Corneal scar and opacity, unspecified	0.214	0.786	0.000
H20 Iridocyclitis	0.208	0.792	0.000
T42.4 Benzodiazepines	0.202	0.798	0.000
H11.1 Conjunctival degenerations and deposits	0.201	0.799	0.000
H54.0 Blindness, both eyes	0.201	0.799	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.200	0.800	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.200	0.800	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.200	0.800	0.000
H54.1 Blindness, one eye, low vision, other eye	0.200	0.800	0.000
H47.2 Optic atrophy	0.198	0.801	0.000
H35.9 Retinal disorder, unspecified	0.198	0.802	0.001
H49.8 Other paralytic strabismus	0.196	0.803	0.000
H49.3 Total (external) ophthalmoplegia	0.196	0.803	0.000
H18.5 Hereditary corneal dystrophies	0.189	0.811	0.000
H10.8 Other conjunctivitis	0.188	0.812	0.000
H10.5 Blepharoconjunctivitis	0.188	0.812	0.000
H10.3 Acute conjunctivitis, unspecified	0.188	0.812	0.000
H10.2 Other acute conjunctivitis	0.188	0.812	0.000
H10.1 Acute atopic conjunctivitis	0.188	0.812	0.000
H10.0 Mucopurulent conjunctivitis	0.188	0.812	0.000
H51.9 Disorder of binocular movement, unspecified	0.186	0.814	0.000
H51.8 Other specified disorders of binocular movement	0.186	0.814	0.000
H51.2 Internuclear ophthalmoplegia	0.186	0.814	0.000
H51.1 Convergence insufficiency and excess	0.186	0.814	0.000
H51.0 Palsy of conjugate gaze	0.186	0.814	0.000
H11.8 Other specified disorders of conjunctiva	0.184	0.816	0.000
H15.8 Other disorders of sclera	0.183	0.817	0.000
H11.2 Conjunctival scars	0.179	0.821	0.000
H10.4 Chronic conjunctivitis	0.179	0.821	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.178	0.822	0.000
H18.6 Keratoconus	0.172	0.828	0.000
H34.2 Other retinal artery occlusions	0.171	0.829	0.001
H50 Other strabismus	0.170	0.829	0.000
H18.4 Corneal degeneration	0.167	0.833	0.000
H40.2 Primary angle-closure glaucoma	0.166	0.833	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.166	0.834	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.165	0.834	0.000
H49.2 Sixth [abducent] nerve palsy	0.164	0.836	0.000
H20.1 Chronic iridocyclitis	0.158	0.841	0.000
H50.2 Vertical strabismus	0.154	0.846	0.000
H20.2 Lens-induced iridocyclitis	0.149	0.851	0.000
H57.8 Other specified disorders of eye and adnexa	0.140	0.860	0.001
H20.9 Iridocyclitis, unspecified	0.137	0.863	0.000
H50.5 Heterophoria	0.129	0.871	0.000
H50.8 Other specified strabismus	0.126	0.874	0.000
H54.7 Unspecified visual loss	0.124	0.876	0.000
H50.6 Mechanical strabismus	0.122	0.878	0.000
H50.3 Intermittent heterotropia	0.122	0.878	0.000
H10.9 Conjunctivitis, unspecified	0.121	0.878	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.120	0.880	0.000
H11.3 Conjunctival haemorrhage	0.118	0.881	0.000
H34.8 Other retinal vascular occlusions	0.117	0.883	0.000
H57.1 Ocular pain	0.108	0.891	0.001
H20.8 Other iridocyclitis	0.102	0.898	0.000
H20.0 Acute and subacute iridocyclitis	0.101	0.898	0.000
H50.4 Other and unspecified heterotropia	0.100	0.900	0.000
H11.0 Pterygium	0.090	0.909	0.000
H50.0 Convergent concomitant strabismus	0.086	0.914	0.000
H50.9 Strabismus, unspecified	0.084	0.916	0.000
H49.0 Third [oculomotor] nerve palsy	0.080	0.919	0.001
H57.9 Disorder of eye and adnexa, unspecified	0.080	0.919	0.001
H52 Disorders of refraction and accommodation	0.075	0.925	0.000
H50.1 Divergent concomitant strabismus	0.066	0.933	0.000
H52.7 Disorder of refraction, unspecified	0.055	0.945	0.000
Z96.1 Presence of intraocular lens	0.054	0.946	0.000
H52.6 Other disorders of refraction	0.054	0.946	0.000
H52.5 Disorders of accommodation	0.054	0.946	0.000
H52.4 Presbyopia	0.054	0.946	0.000
H53 Visual disturbances	0.049	0.951	0.000
H53.0 Amblyopia ex anopsia	0.045	0.955	0.000
H52.3 Anisometropia and aniseikonia	0.045	0.955	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.045	0.955	0.000
H52.2 Astigmatism	0.036	0.964	0.000
H53.6 Night blindness	0.036	0.964	0.000
H53.5 Colour vision deficiencies	0.036	0.964	0.000
H53.3 Other disorders of binocular vision	0.036	0.964	0.000
H52.1 Myopia	0.034	0.965	0.000
H52.0 Hypermetropia	0.031	0.969	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.031	0.969	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.028	0.972	0.000
H01 Other inflammation of eyelid	0.026	0.974	0.000
H05 Disorders of orbit	0.025	0.974	0.000
H53.4 Visual field defects	0.023	0.977	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.022	0.978	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.022	0.978	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.022	0.978	0.000
H04 Disorders of lachrymal system	0.021	0.979	0.000
H05.9 Disorder of orbit, unspecified	0.021	0.979	0.000
H06.2 Dysthyroid exophthalmos	0.021	0.979	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.020	0.979	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.020	0.979	0.000
H53.8 Other visual disturbances	0.019	0.981	0.000
H05.4 Enophthalmos	0.019	0.981	0.000
H01.0 Blepharitis	0.019	0.981	0.000
H01.8 Other specified inflammation of eyelid	0.019	0.981	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.018	0.981	0.000
H05.3 Deformity of orbit	0.018	0.981	0.000
H05.1 Chronic inflammatory disorders of orbit	0.018	0.981	0.000
H53.1 Subjective visual disturbances	0.018	0.982	0.000
H04.3 Acute and unspecified inflammation of lachrymal passages	0.018	0.982	0.000
H01.1 Non-infectious dermatoses of eyelid	0.018	0.982	0.000
H05.8 Other disorders of orbit	0.018	0.982	0.000
H05.2 Exophthalmic conditions	0.017	0.983	0.000
H04.1 Other disorders of lachrymal gland	0.017	0.983	0.000
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.016	0.983	0.000
H04.8 Other disorders of lachrymal system	0.016	0.983	0.000
H04.4 Chronic inflammation of lachrymal passages	0.016	0.984	0.000
H53.9 Visual disturbance, unspecified	0.016	0.984	0.000
H04.6 Other changes in lachrymal passages	0.016	0.984	0.000
H04.0 Dacryoadenitis	0.016	0.984	0.000
H04.9 Disorder of lachrymal system, unspecified	0.015	0.984	0.000
H01.9 Inflammation of eyelid, unspecified	0.014	0.986	0.000
H00 Hordeolum and chalazion	0.014	0.986	0.000
N30.9 Cystitis, unspecified	0.000	0.988	0.012
O62.2 Other uterine inertia	0.000	0.989	0.011
H05.0 Acute inflammation of orbit	0.010	0.989	0.000
H53.2 Diplopia	0.010	0.990	0.000
O62 Abnormalities of forces of labour	0.000	0.991	0.009
O62.3 Precipitate labour	0.000	0.991	0.009
O62.0 Primary inadequate contractions	0.000	0.992	0.008
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.992	0.007
H00.0 Hordeolum and other deep inflammation of eyelid	0.007	0.992	0.000
L50.9 Urticaria, unspecified	0.007	0.993	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.007	0.993	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.993	0.007
O62.8 Other abnormalities of forces of labour	0.000	0.993	0.007
T24.2 Burn of second degree of hip and lower limb, except ankle and foot	0.006	0.994	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.006	0.994	0.000
K66.0 Peritoneal adhesions	0.006	0.994	0.000
H04.5 Stenosis and insufficiency of lachrymal passages	0.006	0.994	0.000
S01.2 Open wound of nose	0.006	0.994	0.000
K66.8 Other specified disorders of peritoneum	0.006	0.994	0.000
N80.9 Endometriosis, unspecified	0.000	0.994	0.006
F60 Specific personality disorders	0.005	0.995	0.000
K66 Other disorders of peritoneum	0.005	0.995	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.005	0.995	0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
L57 Skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.005	0.995	0.000
J20.9 Acute bronchitis, unspecified	0.005	0.995	0.000
F60.7 Dependent personality disorder	0.005	0.995	0.000
N30.1 Interstitial cystitis (chronic)	0.000	0.995	0.005
F60.9 Personality disorder, unspecified	0.005	0.995	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.005	0.995	0.000
L57.4 Cutis laxa senilis	0.005	0.995	0.000
F60.3 Emotionally unstable personality disorder	0.005	0.995	0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot	0.005	0.995	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.005	0.995	0.000
J98.4 Other disorders of lung	0.005	0.995	0.000
S79 Other and unspecified injuries of hip and thigh	0.005	0.995	0.000
F60.5 Anankastic personality disorder	0.005	0.995	0.000
J92.0 Pleural plaque with presence of asbestos	0.005	0.995	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.005	0.995	0.000
O62.1 Secondary uterine inertia	0.000	0.995	0.004
N30.0 Acute cystitis	0.000	0.995	0.005

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations