TreeWAS – Variant ID: rs1210898

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E66.9 Obesity, unspecified	0.000	0.992	0.008
E66 Obesity	0.000	0.994	0.006
J44.9 Chronic obstructive pulmonary disease, unspecified	0.000	0.995	0.005
I35.0 Aortic (valve) stenosis	0.005	0.995	0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.000	0.995	0.005
E66.8 Other obesity	0.000	0.995	0.005
J44 Other chronic obstructive pulmonary disease	0.000	0.995	0.005
L90.5 Scar conditions and fibrosis of skin	0.004	0.996	0.000
E66.0 Obesity due to excess calories	0.000	0.996	0.004
E66.1 Drug-induced obesity	0.000	0.996	0.004
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.996	0.004
Z42.1 Follow-up care involving plastic surgery of breast	0.004	0.996	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.000	0.996	0.004
D70 Agranulocytosis	0.000	0.997	0.003
N73.6 Female pelvic peritoneal adhesions	0.000	0.997	0.003
H66.3 Other chronic suppurative otitis media	0.000	0.997	0.003
Q21.1 Atrial septal defect	0.000	0.997	0.003
Q21 Congenital malformations of cardiac septa	0.000	0.997	0.003
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.000	0.997	0.003
I24.8 Other forms of acute ischaemic heart disease	0.000	0.997	0.003
D73 Diseases of spleen	0.000	0.997	0.003
R59.0 Localised enlarged lymph nodes	0.000	0.997	0.003
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
H65 Nonsuppurative otitis media	0.000	0.997	0.003
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
Q21.9 Congenital malformation of cardiac septum, unspecified	0.000	0.997	0.003
Q21.0 Ventricular septal defect	0.000	0.997	0.003
D75.8 Other specified diseases of blood and blood-forming organs	0.000	0.997	0.003
H65.3 Chronic mucoid otitis media	0.000	0.997	0.003
D75 Other diseases of blood and blood-forming organs	0.000	0.997	0.003
L90 Atrophic disorders of skin	0.003	0.997	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.997	0.003
D73.5 Infarction of spleen	0.000	0.997	0.003
H65.0 Acute serous otitis media	0.000	0.997	0.003
H65.4 Other chronic nonsuppurative otitis media	0.000	0.997	0.003
D73.3 Abscess of spleen	0.000	0.997	0.003
C34.3 Lower lobe, bronchus or lung	0.000	0.997	0.003
L90.0 Lichen sclerosus et atrophicus	0.003	0.997	0.000
D73.8 Other diseases of spleen	0.000	0.997	0.003
H65.2 Chronic serous otitis media	0.000	0.997	0.003
Q20-Q28 Congenital malformations of the circulatory system	0.000	0.997	0.003
Q21.3 Tetralogy of Fallot	0.000	0.997	0.002
Q21.8 Other congenital malformations of cardiac septa	0.000	0.997	0.002
H66 Suppurative and unspecified otitis media	0.000	0.997	0.003
D73.1 Hypersplenism	0.000	0.997	0.002
Q21.4 Aortopulmonary septal defect	0.000	0.997	0.002
Q21.2 Atrioventricular septal defect	0.000	0.997	0.002
D73.9 Disease of spleen, unspecified	0.000	0.997	0.002
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
E65-E68 Obesity and other hyperalimentation	0.000	0.997	0.002
K66.0 Peritoneal adhesions	0.003	0.997	0.000
D73.4 Cyst of spleen	0.000	0.997	0.002
D73.2 Chronic congestive splenomegaly	0.000	0.998	0.002
D73.0 Hyposplenism	0.000	0.998	0.002
D75.0 Familial erythrocytosis	0.000	0.998	0.002
Q27 Other congenital malformations of peripheral vascular system	0.000	0.998	0.002
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.998	0.002
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
L90.8 Other atrophic disorders of skin	0.002	0.998	0.000
N73 Other female pelvic inflammatory diseases	0.000	0.998	0.002
Q28 Other congenital malformations of circulatory system	0.000	0.998	0.002
H65.9 Nonsuppurative otitis media, unspecified	0.000	0.998	0.002
L90.9 Atrophic disorder of skin, unspecified	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.000	0.998	0.002
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.998	0.002
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.998	0.002
Q22 Congenital malformations of pulmonary and tricuspid valves	0.000	0.998	0.002
H65-H75 Diseases of middle ear and mastoid	0.000	0.998	0.002
C34.9 Bronchus or lung, unspecified	0.000	0.998	0.002
H65.1 Other acute nonsuppurative otitis media	0.000	0.998	0.002
N73.9 Female pelvic inflammatory disease, unspecified	0.000	0.998	0.002
D75.2 Essential thrombocytosis	0.000	0.998	0.002
L90.6 Striae atrophicae	0.002	0.998	0.000
L90.4 Acrodermatitis chronica atrophicans	0.002	0.998	0.000
L90.3 Atrophoderma of Pasini and Pierini	0.002	0.998	0.000
L90.2 Anetoderma of Jadassohn-Pellizzari	0.002	0.998	0.000
L90.1 Anetoderma of Schweninger-Buzzi	0.002	0.998	0.000
Q27.3 Peripheral arteriovenous malformation	0.000	0.998	0.002
N28.8 Other specified disorders of kidney and ureter	0.000	0.998	0.002
Q28.2 Arteriovenous malformation of cerebral vessels	0.000	0.998	0.002
Q25 Congenital malformations of great arteries	0.000	0.998	0.002
H66.0 Acute suppurative otitis media	0.000	0.998	0.002
Z80.0 Family history of malignant neoplasm of digestive organs	0.002	0.998	0.000
T40.2 Other opioids	0.000	0.998	0.002
Q22.5 Ebstein's anomaly	0.000	0.998	0.002
D72 Other disorders of white blood cells	0.000	0.998	0.002
H71 Cholesteatoma of middle ear	0.000	0.998	0.002
C77.3 Axillary and upper limb lymph nodes	0.002	0.998	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.998	0.002
Q20 Congenital malformations of cardiac chambers and connexions	0.000	0.998	0.002
H66.2 Chronic atticoantral suppurative otitis media	0.000	0.998	0.002
H70 Mastoiditis and related conditions	0.000	0.998	0.002
H72 Perforation of tympanic membrane	0.000	0.998	0.002
Q26 Congenital malformations of great veins	0.000	0.998	0.002
H66.1 Chronic tubotympanic suppurative otitis media	0.000	0.998	0.002
N73.0 Acute parametritis and pelvic cellulitis	0.000	0.998	0.002
D76.3 Other histiocytosis syndromes	0.000	0.998	0.002
Q24 Other congenital malformations of heart	0.000	0.998	0.002
H66.4 Suppurative otitis media, unspecified	0.000	0.998	0.002
E67 Other hyperalimentation	0.000	0.998	0.002
E68 Sequelae of hyperalimentation	0.000	0.998	0.002
Q27.8 Other specified congenital malformations of peripheral vascular system	0.000	0.998	0.002
Q27.1 Congenital renal artery stenosis	0.000	0.998	0.002
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.000	0.998	0.002
D75.1 Secondary polycythaemia	0.000	0.998	0.002
Q22.1 Congenital pulmonary valve stenosis	0.000	0.998	0.002
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.000	0.998	0.002
Q27.4 Congenital phlebectasia	0.000	0.998	0.002
Q27.2 Other congenital malformations of renal artery	0.000	0.998	0.002
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.000	0.998	0.002
S82.80 Fractures of other parts of lower leg (closed)	0.002	0.998	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.998	0.002
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.998	0.002
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.998	0.002
Q28.0 Arteriovenous malformation of precerebral vessels	0.000	0.998	0.002
H68 Eustachian salpingitis and obstruction	0.000	0.998	0.002
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.000	0.998	0.002
H72.0 Central perforation of tympanic membrane	0.000	0.998	0.002
N73.4 Female chronic pelvic peritonitis	0.000	0.998	0.002
N73.3 Female acute pelvic peritonitis	0.000	0.998	0.002
N73.2 Unspecified parametritis and pelvic cellulitis	0.000	0.998	0.002
Q28.9 Congenital malformation of circulatory system, unspecified	0.000	0.998	0.002
Q28.8 Other specified congenital malformations of circulatory system	0.000	0.998	0.002
Q28.1 Other malformations of precerebral vessels	0.000	0.998	0.002
C34.2 Middle lobe, bronchus or lung	0.000	0.998	0.002
Q28.3 Other malformations of cerebral vessels	0.000	0.998	0.002
R26.8 Other and unspecified abnormalities of gait and mobility	0.000	0.998	0.002
D74.9 Methaemoglobinaemia, unspecified	0.000	0.998	0.002
D74.8 Other methaemoglobinaemias	0.000	0.998	0.002
D74.0 Congenital methaemoglobinaemia	0.000	0.998	0.002
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.000	0.998	0.002
Q22.8 Other congenital malformations of tricuspid valve	0.000	0.998	0.002
Q22.6 Hypoplastic right heart syndrome	0.000	0.998	0.002
Q22.4 Congenital tricuspid stenosis	0.000	0.998	0.002
Q22.3 Other congenital malformations of pulmonary valve	0.000	0.998	0.002
Q22.2 Congenital pulmonary valve insufficiency	0.000	0.998	0.002
Q22.0 Pulmonary valve atresia	0.000	0.998	0.002
E65 Localised adiposity	0.000	0.998	0.002
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.002
H67 Otitis media in diseases classified elsewhere	0.000	0.998	0.002
K81.1 Chronic cholecystitis	0.000	0.998	0.002
M25.77 Osteophyte (Ankle and foot)	0.002	0.998	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.000	0.998	0.002
N73.8 Other specified female pelvic inflammatory diseases	0.000	0.998	0.002
Q25.3 Stenosis of aorta	0.000	0.998	0.002
H69 Other disorders of Eustachian tube	0.000	0.998	0.002
J40-J47 Chronic lower respiratory diseases	0.000	0.998	0.002
H70.9 Mastoiditis, unspecified	0.000	0.998	0.002
Q25.0 Patent ductus arteriosus	0.000	0.998	0.002
J40 Bronchitis, not specified as acute or chronic	0.000	0.998	0.002
N73.5 Female pelvic peritonitis, unspecified	0.000	0.998	0.002
Q25.4 Other congenital malformations of aorta	0.000	0.998	0.002
D72.1 Eosinophilia	0.000	0.998	0.002
Q25.9 Congenital malformation of great arteries, unspecified	0.000	0.998	0.002
Q25.8 Other congenital malformations of great arteries	0.000	0.998	0.002
Q25.5 Atresia of pulmonary artery	0.000	0.998	0.002
Q25.2 Atresia of aorta	0.000	0.998	0.002
T39.0 Salicylates	0.000	0.998	0.002
H70.0 Acute mastoiditis	0.000	0.998	0.002
K86.0 Alcohol-induced chronic pancreatitis	0.000	0.998	0.002
N81.6 Rectocele	0.000	0.998	0.002
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.000	0.998	0.002
J45.0 Predominantly allergic asthma	0.000	0.998	0.002
N73.1 Chronic parametritis and pelvic cellulitis	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.000	0.998	0.002
Q25.6 Stenosis of pulmonary artery	0.000	0.998	0.002
Y40.3 Macrolides	0.000	0.998	0.002
D23.7 Skin of lower limb, including hip	0.000	0.998	0.002
E78.5 Hyperlipidaemia, unspecified	0.000	0.998	0.002
H70.8 Other mastoiditis and related conditions	0.000	0.998	0.002
Q25.1 Coarctation of aorta	0.000	0.998	0.002
T40.5 Cocaine	0.000	0.998	0.002
D72.9 Disorder of white blood cells, unspecified	0.000	0.998	0.002
D72.0 Genetic anomalies of leukocytes	0.000	0.998	0.002
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.000	0.998	0.002
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.000	0.998	0.002
Q20.6 Isomerism of atrial appendages	0.000	0.998	0.002
Q20.5 Discordant atrioventricular connexion	0.000	0.998	0.002
Q20.4 Double inlet ventricle	0.000	0.998	0.002
Q20.3 Discordant ventriculoarterial connexion	0.000	0.998	0.002
Q20.2 Double outlet left ventricle	0.000	0.998	0.002
Q20.1 Double outlet right ventricle	0.000	0.998	0.002
Q20.0 Common arterial trunk	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.000	0.998	0.002
H70.2 Petrositis	0.000	0.998	0.002
H72.2 Other marginal perforations of tympanic membrane	0.000	0.998	0.002
Q24.5 Malformation of coronary vessels	0.000	0.998	0.002
T40.3 Methadone	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.998	0.002
Q26.9 Congenital malformation of great vein, unspecified	0.000	0.998	0.002
Q26.8 Other congenital malformations of great veins	0.000	0.998	0.002
Q26.6 Portal vein-hepatic artery fistula	0.000	0.998	0.002
Q26.5 Anomalous portal venous connexion	0.000	0.998	0.002
Q26.3 Partial anomalous pulmonary venous connexion	0.000	0.998	0.002
Q26.2 Total anomalous pulmonary venous connexion	0.000	0.998	0.002
Q26.1 Persistent left superior vena cava	0.000	0.998	0.002
Q26.0 Congenital stenosis of vena cava	0.000	0.998	0.002
Q23 Congenital malformations of aortic and mitral valves	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
Y40 Systemic antibiotics	0.000	0.998	0.002
Z42 Follow-up care involving plastic surgery	0.002	0.998	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.998	0.002
H68.1 Obstruction of Eustachian tube	0.000	0.998	0.002
H72.8 Other perforations of tympanic membrane	0.000	0.998	0.002
N28.9 Disorder of kidney and ureter, unspecified	0.000	0.998	0.002
Q24.6 Congenital heart block	0.000	0.998	0.002
Q24.3 Pulmonary infundibular stenosis	0.000	0.998	0.002
Q24.2 Cor triatriatum	0.000	0.998	0.002
Q24.1 Levocardia	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.000	0.998	0.002
E67.8 Other specified hyperalimentation	0.000	0.998	0.002
E67.3 Hypervitaminosis D	0.000	0.998	0.002
E67.2 Megavitamin-B6 syndrome	0.000	0.998	0.002
E67.1 Hypercarotenaemia	0.000	0.998	0.002
E67.0 Hypervitaminosis A	0.000	0.998	0.002
H70.1 Chronic mastoiditis	0.000	0.998	0.002
Y40.8 Other systemic antibiotics	0.000	0.998	0.002
T36-T50 Poisoning by drugs, medicaments and biological substances	0.000	0.998	0.002
Q24.0 Dextrocardia	0.000	0.998	0.002
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.000	0.998	0.001
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.998	0.002
H74 Other disorders of middle ear and mastoid	0.000	0.998	0.002
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
H68.0 Eustachian salpingitis	0.000	0.998	0.002
Q24.4 Congenital subaortic stenosis	0.000	0.998	0.001
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.000	0.998	0.002
T40.8 Lysergide [LSD]	0.000	0.998	0.002
T40.7 Cannabis (derivatives)	0.000	0.998	0.002
T40.0 Opium	0.000	0.998	0.002
Y40.9 Systemic antibiotic, unspecified	0.000	0.998	0.002
F60.9 Personality disorder, unspecified	0.000	0.998	0.002
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
Q40.8 Other specified congenital malformations of upper alimentary tract	0.000	0.998	0.002
H67.8 Otitis media in other diseases classified elsewhere	0.000	0.998	0.001
H67.1 Otitis media in viral diseases classified elsewhere	0.000	0.998	0.001
H67.0 Otitis media in bacterial diseases classified elsewhere	0.000	0.998	0.001
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.000	0.998	0.001
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
I08 Multiple valve diseases	0.002	0.998	0.000
Q40 Other congenital malformations of upper alimentary tract	0.000	0.998	0.002
H69.8 Other specified disorders of Eustachian tube	0.000	0.998	0.002
Y40.5 Aminoglycosides	0.000	0.998	0.002
T40.1 Heroin	0.000	0.998	0.002
C34.1 Upper lobe, bronchus or lung	0.000	0.998	0.002
H69.0 Patulous Eustachian tube	0.000	0.998	0.001
H72.1 Attic perforation of tympanic membrane	0.000	0.998	0.001
J47 Bronchiectasis	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
Q24.9 Congenital malformation of the heart, unspecified	0.000	0.998	0.001
J45 Asthma	0.000	0.998	0.002
M54.39 Sciatica (Site unspecified)	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
Y40.0 Penicillins	0.000	0.998	0.002
H73 Other disorders of tympanic membrane	0.000	0.998	0.001
J41 Simple and mucopurulent chronic bronchitis	0.000	0.998	0.001
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.000	0.998	0.002
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.998	0.002
K83.1 Obstruction of bile duct	0.000	0.998	0.002
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.000	0.998	0.001
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.001
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.000	0.998	0.001
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.000	0.998	0.002
T36 Poisoning by systemic antibiotics	0.000	0.998	0.002
H74.2 Discontinuity and dislocation of ear ossicles	0.000	0.998	0.001
Q40.3 Congenital malformation of stomach, unspecified	0.000	0.998	0.001
T50.8 Diagnostic agents	0.000	0.998	0.001
Y40.6 Rifamycins	0.000	0.998	0.001
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
C62.9 Testis, unspecified	0.000	0.998	0.002
H66.9 Otitis media, unspecified	0.000	0.998	0.001
T40.6 Other and unspecified narcotics	0.000	0.998	0.001
Z42.9 Follow-up care involving plastic surgery, unspecified	0.001	0.998	0.000
N28 Other disorders of kidney and ureter, not elsewhere classified	0.000	0.998	0.002
H74.3 Other acquired abnormalities of ear ossicles	0.000	0.998	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.998	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.998	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.998	0.001
Q23.2 Congenital mitral stenosis	0.000	0.998	0.001
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.001
T39.2 Pyrazolone derivatives	0.000	0.998	0.001
T45.2 Vitamins, not elsewhere classified	0.000	0.998	0.001
Y40.2 Chloramphenicol group	0.000	0.998	0.001
Z42.4 Follow-up care involving plastic surgery of lower extremity	0.001	0.998	0.000
Z42.2 Follow-up care involving plastic surgery of other parts of trunk	0.001	0.998	0.000
Z42.0 Follow-up care involving plastic surgery of head and neck	0.002	0.998	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.000	0.998	0.001
I07.1 Tricuspid insufficiency	0.000	0.998	0.001
I08.2 Disorders of both aortic and tricuspid valves	0.001	0.998	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.998	0.002
K86.3 Pseudocyst of pancreas	0.000	0.998	0.002
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.001
Q40.2 Other specified congenital malformations of stomach	0.000	0.998	0.001
Q40.1 Congenital hiatus hernia	0.000	0.998	0.001
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
Z42.8 Follow-up care involving plastic surgery of other body part	0.001	0.998	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.000	0.998	0.001
T41 Poisoning by anaesthetics and therapeutic gases	0.000	0.998	0.001
C34.0 Main bronchus	0.000	0.998	0.001
H69.9 Eustachian tube disorder, unspecified	0.000	0.998	0.001
H74.8 Other specified disorders of middle ear and mastoid	0.000	0.998	0.001
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.001	0.998	0.000
I72.9 Aneurysm of unspecified site	0.000	0.998	0.001
O04.9 Complete or unspecified, without complication	0.002	0.998	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.998	0.001
R50.0 Fever with chills	0.002	0.998	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.000	0.998	0.001
T45.1 Antineoplastic and immunosuppressive drugs	0.000	0.998	0.001
T47.1 Other antacids and anti-gastric-secretion drugs	0.000	0.998	0.001
T50.4 Drugs affecting uric acid metabolism	0.000	0.998	0.001
Z42.3 Follow-up care involving plastic surgery of upper extremity	0.001	0.998	0.000
F60 Specific personality disorders	0.000	0.998	0.002
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.000	0.998	0.001
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.000	0.998	0.001
Y57 Other and unspecified drugs and medicaments	0.000	0.998	0.001
Q38-Q45 Other congenital malformations of the digestive system	0.000	0.998	0.001
F22.0 Delusional disorder	0.000	0.998	0.001
H74.9 Disorder of middle ear and mastoid, unspecified	0.000	0.998	0.001
I08.9 Multiple valve disease, unspecified	0.001	0.998	0.000
I08.1 Disorders of both mitral and tricuspid valves	0.001	0.998	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.998	0.001
Q23.3 Congenital mitral insufficiency	0.000	0.998	0.001
T50.7 Analeptics and opioid receptor antagonists	0.000	0.998	0.001
T50.5 Appetite depressants	0.000	0.998	0.001
T50.3 Electrolytic, caloric and water-balance agents	0.000	0.998	0.001
T50.0 Mineralocorticoids and their antagonists	0.000	0.998	0.001
T81.4 Infection following a procedure, not elsewhere classified	0.002	0.998	0.000
F60.3 Emotionally unstable personality disorder	0.000	0.998	0.001
Q40.9 Congenital malformation of upper alimentary tract, unspecified	0.000	0.998	0.001
Q40.0 Congenital hypertrophic pyloric stenosis	0.000	0.998	0.001
Y40.4 Tetracyclines	0.000	0.998	0.001
J42 Unspecified chronic bronchitis	0.000	0.998	0.001
M19.91 Arthrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M54.59 Low back pain (Site unspecified)	0.002	0.998	0.000
D72.8 Other specified disorders of white blood cells	0.000	0.998	0.001
H73.0 Acute myringitis	0.000	0.998	0.001
I74.8 Embolism and thrombosis of other arteries	0.000	0.998	0.001
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.001
T47.4 Other laxatives	0.000	0.998	0.001
T47.2 Stimulant laxatives	0.000	0.998	0.001
T50.1 Loop [high-ceiling] diuretics	0.000	0.998	0.001
Y40.7 Antifungal antibiotics, systemically used	0.000	0.998	0.001
F60.5 Anankastic personality disorder	0.000	0.999	0.001
H74.0 Tympanosclerosis	0.000	0.999	0.001
N28.0 Ischaemia and infarction of kidney	0.000	0.999	0.001
T36.4 Tetracyclines	0.000	0.999	0.001
T36.3 Macrolides	0.000	0.999	0.001
T46.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.999	0.001
I74 Arterial embolism and thrombosis	0.000	0.999	0.001
K86 Other diseases of pancreas	0.000	0.999	0.001
H74.1 Adhesive middle ear disease	0.000	0.999	0.001
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.999	0.001
N36.8 Other specified disorders of urethra	0.000	0.999	0.001
Q05.9 Spina bifida, unspecified	0.000	0.999	0.001
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.000	0.999	0.001
N70 Salpingitis and oophoritis	0.000	0.999	0.001
Q38 Other congenital malformations of tongue, mouth and pharynx	0.000	0.999	0.001
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.001	0.999	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.999	0.001
F60.7 Dependent personality disorder	0.000	0.999	0.001
F60.0 Paranoid personality disorder	0.000	0.999	0.001
J41.8 Mixed simple and mucopurulent chronic bronchitis	0.000	0.999	0.001
J41.1 Mucopurulent chronic bronchitis	0.000	0.999	0.001
J45.8 Mixed asthma	0.000	0.999	0.001
T36.8 Other systemic antibiotics	0.000	0.999	0.001
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.000	0.999	0.001
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.999	0.001
T45.5 Anticoagulants	0.000	0.999	0.001
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.000	0.999	0.001
T47.8 Other agents primarily affecting the gastro-intestinal system	0.000	0.999	0.001
T47.7 Emetics	0.000	0.999	0.001
T47.5 Digestants	0.000	0.999	0.001
T47.3 Saline and osmotic laxatives	0.000	0.999	0.001
K85 Acute pancreatitis	0.000	0.999	0.001
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.000	0.999	0.001
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.000	0.999	0.001
F60.2 Dissocial personality disorder	0.000	0.999	0.001
J45.1 Nonallergic asthma	0.000	0.999	0.001
T36.9 Systemic antibiotic, unspecified	0.000	0.999	0.001
T36.7 Antifungal antibiotics, systemically used	0.000	0.999	0.001
T36.6 Rifamycins	0.000	0.999	0.001
T36.5 Aminoglycosides	0.000	0.999	0.001
T36.2 Chloramphenicol group	0.000	0.999	0.001
T45.9 Primarily systemic and haematological agent, unspecified	0.000	0.999	0.001
T45.8 Other primarily systemic and haematological agents	0.000	0.999	0.001
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.000	0.999	0.001
T45.6 Fibrinolysis-affecting drugs	0.000	0.999	0.001
T45.3 Enzymes, not elsewhere classified	0.000	0.999	0.001
Y57.6 Other diagnostic agents	0.000	0.999	0.001
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.000	0.999	0.001
Q00-Q07 Congenital malformations of the nervous system	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
H53.0 Amblyopia ex anopsia	0.000	0.999	0.001
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.999	0.001
J41.0 Simple chronic bronchitis	0.000	0.999	0.001
K85.2 Alcohol-induced acute pancreatitis	0.000	0.999	0.001
Q89.2 Congenital malformations of other endocrine glands	0.000	0.999	0.001
T41.2 Other and unspecified general anaesthetics	0.000	0.999	0.001
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.999	0.001
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.999	0.001
T47.6 Antidiarrhoeal drugs	0.000	0.999	0.001
Q05 Spina bifida	0.000	0.999	0.001
Q39 Congenital malformations of oesophagus	0.000	0.999	0.001
H73.1 Chronic myringitis	0.000	0.999	0.001
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.999	0.001
K86.1 Other chronic pancreatitis	0.000	0.999	0.001
Q38.7 Pharyngeal pouch	0.000	0.999	0.001
T41.5 Therapeutic gases	0.000	0.999	0.001
T41.4 Anaesthetic, unspecified	0.000	0.999	0.001
T41.3 Local anaesthetics	0.000	0.999	0.001
T41.1 Intravenous anaesthetics	0.000	0.999	0.001
T41.0 Inhaled anaesthetics	0.000	0.999	0.001
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
T45.4 Iron and its compounds	0.000	0.999	0.001
T46.8 Antivaricose drugs, including sclerosing agents	0.000	0.999	0.001
T46.7 Peripheral vasodilators	0.000	0.999	0.001
T46.3 Coronary vasodilators, not elsewhere classified	0.000	0.999	0.001
T47.0 Histamine H(2)-receptor antagonists	0.000	0.999	0.001
T48.6 Antiasthmatics, not elsewhere classified	0.000	0.999	0.001
J46 Status asthmaticus	0.000	0.999	0.001
Q45 Other congenital malformations of digestive system	0.000	0.999	0.001
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.001	0.999	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.999	0.001
Q12.0 Congenital cataract	0.000	0.999	0.001
T43.9 Psychotropic drug, unspecified	0.000	0.999	0.001
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.999	0.001
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.999	0.001
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.999	0.001
T44.1 Other parasympathomimetics [cholinergics]	0.000	0.999	0.001
T44.0 Anticholinesterase agents	0.000	0.999	0.001
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.000	0.999	0.001
T48.4 Expectorants	0.000	0.999	0.001
T48.3 Antitussives	0.000	0.999	0.001
T48.2 Other and unspecified agents primarily acting on muscles	0.000	0.999	0.001
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.000	0.999	0.001
T48.0 Oxytocic drugs	0.000	0.999	0.001
T49.9 Topical agent, unspecified	0.000	0.999	0.001
T49.8 Other topical agents	0.000	0.999	0.001
T49.7 Dental drugs, topically applied	0.000	0.999	0.001
T49.6 Otorhinolaryngological drugs and preparations	0.000	0.999	0.001
T49.5 Ophthalmological drugs and preparations	0.000	0.999	0.001
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.999	0.001
T49.3 Emollients, demulcents and protectants	0.000	0.999	0.001
T49.2 Local astringents and local detergents	0.000	0.999	0.001
T49.1 Antipruritics	0.000	0.999	0.001
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.999	0.001
Y57.7 Vitamins, not elsewhere classified	0.000	0.999	0.001
Y57.4 Pharmaceutical excipients	0.000	0.999	0.001
Y57.3 Alcohol deterrents	0.000	0.999	0.001
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.000	0.999	0.001
Y57.1 Lipotropic drugs	0.000	0.999	0.001
Y57.0 Appetite depressants [anorectics]	0.000	0.999	0.001
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.000	0.999	0.001
Q42 Congenital absence, atresia and stenosis of large intestine	0.000	0.999	0.001
Q41 Congenital absence, atresia and stenosis of small intestine	0.000	0.999	0.001
F60.4 Histrionic personality disorder	0.000	0.999	0.001
F60.1 Schizoid personality disorder	0.000	0.999	0.001
H73.9 Disorder of tympanic membrane, unspecified	0.000	0.999	0.001
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.999	0.001
K85.3 Drug-induced acute pancreatitis	0.000	0.999	0.001
K86.2 Cyst of pancreas	0.000	0.999	0.001
Q79.6 Ehlers-Danlos syndrome	0.000	0.999	0.001
S82.8 Fractures of other parts of lower leg	0.001	0.999	0.000
T36.0 Penicillins	0.000	0.999	0.001
T43.6 Psychostimulants with abuse potential	0.000	0.999	0.001
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.999	0.001
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.999	0.001
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.999	0.001
Q07 Other congenital malformations of nervous system	0.000	0.999	0.001
Q12 Congenital lens malformations	0.000	0.999	0.001
F60.8 Other specific personality disorders	0.000	0.999	0.001
K85.8 Other acute pancreatitis	0.000	0.999	0.001
Q38.6 Other congenital malformations of mouth	0.000	0.999	0.001
Q38.1 Ankyloglossia	0.000	0.999	0.001
T39.1 4-Aminophenol derivatives	0.000	0.999	0.001
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.999	0.001
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.000	0.999	0.001
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.999	0.001
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.000	0.999	0.001
F60.6 Anxious [avoidant] personality disorder	0.000	0.999	0.001
K83.8 Other specified diseases of biliary tract	0.000	0.999	0.001
M54.4 Lumbago with sciatica	0.000	0.999	0.001
Q38.0 Congenital malformations of lips, not elsewhere classified	0.000	0.999	0.001
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.000	0.999	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.000	0.999	0.001
T48.5 Anti-common-cold drugs	0.000	0.999	0.001
Y57.8 Other drugs and medicaments	0.000	0.999	0.001
Q89 Other congenital malformations, not elsewhere classified	0.000	0.999	0.001
Q80-Q89 Other congenital malformations	0.000	0.999	0.001
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.999	0.001
Q07.0 Arnold-Chiari syndrome	0.000	0.999	0.001
Q23.1 Congenital insufficiency of aortic valve	0.000	0.999	0.001
Q38.4 Congenital malformations of salivary glands and ducts	0.000	0.999	0.001
Q38.3 Other congenital malformations of tongue	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations