TreeWAS – Variant ID: rs12121801

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E03.9 Hypothyroidism, unspecified	0.993	0.007	0.000
E03 Other hypothyroidism	0.843	0.157	0.000
E03.8 Other specified hypothyroidism	0.795	0.205	0.000
E03.5 Myxoedema coma	0.605	0.395	0.000
E03.4 Atrophy of thyroid (acquired)	0.605	0.395	0.000
E03.3 Postinfectious hypothyroidism	0.605	0.395	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.605	0.395	0.000
E03.1 Congenital hypothyroidism without goitre	0.605	0.395	0.000
E03.0 Congenital hypothyroidism with diffuse goitre	0.605	0.395	0.000
E00-E07 Disorders of thyroid gland	0.320	0.680	0.000
E06 Thyroiditis	0.271	0.729	0.000
E07 Other disorders of thyroid	0.248	0.752	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.230	0.770	0.000
E00 Congenital iodine-deficiency syndrome	0.230	0.770	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.230	0.770	0.000
E06.9 Thyroiditis, unspecified	0.224	0.776	0.000
E06.3 Autoimmune thyroiditis	0.212	0.788	0.000
E07.8 Other specified disorders of thyroid	0.207	0.793	0.000
E06.5 Other chronic thyroiditis	0.194	0.806	0.000
E06.4 Drug-induced thyroiditis	0.194	0.806	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.194	0.806	0.000
E06.1 Subacute thyroiditis	0.194	0.806	0.000
E06.0 Acute thyroiditis	0.194	0.806	0.000
E04 Other non-toxic goitre	0.183	0.817	0.000
E07.1 Dyshormogenetic goitre	0.178	0.822	0.000
E07.0 Hypersecretion of calcitonin	0.178	0.822	0.000
E04.1 Non-toxic single thyroid nodule	0.172	0.828	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.165	0.835	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.165	0.835	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.165	0.835	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.165	0.835	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.165	0.835	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.165	0.835	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.165	0.835	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.165	0.835	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.162	0.838	0.000
E07.9 Disorder of thyroid, unspecified	0.157	0.843	0.000
E05.9 Thyrotoxicosis, unspecified	0.136	0.864	0.000
E04.8 Other specified non-toxic goitre	0.132	0.868	0.000
E05.5 Thyroid crisis or storm	0.116	0.883	0.000
E05.4 Thyrotoxicosis factitia	0.116	0.883	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.116	0.883	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.116	0.883	0.000
E04.0 Non-toxic diffuse goitre	0.116	0.884	0.000
E05.8 Other thyrotoxicosis	0.115	0.885	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.089	0.910	0.000
E04.2 Non-toxic multinodular goitre	0.067	0.933	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.044	0.956	0.000
E04.9 Non-toxic goitre, unspecified	0.036	0.963	0.001
I67.9 Cerebrovascular disease, unspecified	0.000	0.993	0.007
N36.2 Urethral caruncle	0.000	0.993	0.007
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.007	0.993	0.000
Y43.3 Other antineoplastic drugs	0.000	0.994	0.006
L57.0 Actinic keratosis	0.006	0.994	0.000
D35.1 Parathyroid gland	0.000	0.994	0.006
H26.4 After-cataract	0.000	0.995	0.005
L57 Skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene	0.000	0.995	0.005
L57.4 Cutis laxa senilis	0.005	0.995	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
M06.9 Rheumatoid arthritis, unspecified	0.004	0.996	0.000
L57.9 Skin changes due to chronic exposure to nonionising radiation, unspecified	0.004	0.996	0.000
L57.5 Actinic granuloma	0.004	0.996	0.000
L57.3 Poikiloderma of Civatte	0.004	0.996	0.000
L57.2 Cutis rhomboidalis nuchae	0.004	0.996	0.000
L57.1 Actinic reticuloid	0.004	0.996	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
N36 Other disorders of urethra	0.000	0.996	0.004
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.004	0.996	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.996	0.004
S02.10 Fracture of base of skull (closed)	0.000	0.996	0.004
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.996	0.004
N36.8 Other specified disorders of urethra	0.000	0.996	0.004
R09.1 Pleurisy	0.004	0.996	0.000
D35.0 Adrenal gland	0.000	0.996	0.003
S62.30 Fracture of other metacarpal bone (closed)	0.003	0.996	0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.003	0.997	0.000
Z82.3 Family history of stroke	0.000	0.997	0.003
Z99.1 Dependence on respirator	0.000	0.997	0.003
M06.98 Rheumatoid arthritis, unspecified (Other)	0.003	0.997	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.003	0.997	0.000
K41 Femoral hernia	0.000	0.997	0.003
E21.0 Primary hyperparathyroidism	0.000	0.997	0.003
D35.2 Pituitary gland	0.000	0.997	0.003
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene	0.000	0.997	0.003
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
D35.9 Endocrine gland, unspecified	0.000	0.997	0.003
D35.8 Pluriglandular involvement	0.000	0.997	0.003
D35.7 Other specified endocrine glands	0.000	0.997	0.003
D35.6 Aortic body and other paraganglia	0.000	0.997	0.003
D35.5 Carotid body	0.000	0.997	0.003
D35.4 Pineal gland	0.000	0.997	0.003
D35.3 Craniopharyngeal duct	0.000	0.997	0.003
N36.9 Urethral disorder, unspecified	0.000	0.997	0.003
Y43 Primarily systemic agents	0.000	0.997	0.003
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.003	0.997	0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.003	0.997	0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.003	0.997	0.000
N36.1 Urethral diverticulum	0.000	0.997	0.002
Z94.0 Kidney transplant status	0.000	0.997	0.003
K25.7 Chronic without haemorrhage or perforation	0.000	0.997	0.003
Z48.8 Other specified surgical follow-up care	0.000	0.997	0.003
Z99.2 Dependence on renal dialysis	0.000	0.997	0.003
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.997	0.003
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.002	0.997	0.000
K41.4 Unilateral or unspecified femoral hernia, with gangrene	0.000	0.997	0.002
K41.2 Bilateral femoral hernia, without obstruction or gangrene	0.000	0.997	0.002
K41.1 Bilateral femoral hernia, with gangrene	0.000	0.997	0.002
K41.0 Bilateral femoral hernia, with obstruction, without gangrene	0.000	0.997	0.002
L56 Other acute skin changes due to ultraviolet radiation	0.002	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
M06 Other rheumatoid arthritis	0.002	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.002
Y43.1 Antineoplastic antimetabolites	0.000	0.998	0.002
L59 Other disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.000	0.998	0.002
N36.0 Urethral fistula	0.000	0.998	0.002
M06.4 Inflammatory polyarthropathy	0.002	0.998	0.000
Y43.9 Primarily systemic agent, unspecified	0.000	0.998	0.002
Y43.8 Other primarily systemic agents, not elsewhere classified	0.000	0.998	0.002
Y43.6 Enzymes, not elsewhere classified	0.000	0.998	0.002
Y43.5 Acidifying and alkalising agents	0.000	0.998	0.002
Y43.2 Antineoplastic natural products	0.000	0.998	0.002
L58 Radiodermatitis	0.002	0.998	0.000
L55 Sunburn	0.002	0.998	0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.998	0.002
F03 Unspecified dementia	0.002	0.998	0.000
D10.3 Other and unspecified parts of mouth	0.002	0.998	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.002	0.998	0.000
M06.3 Rheumatoid nodule	0.002	0.998	0.000
Z99.3 Dependence on wheelchair	0.000	0.998	0.002
I44.6 Other and unspecified fascicular block	0.002	0.998	0.000
L59.8 Other specified disorders of skin and subcutaneous tissue related to radiation	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.000	0.998	0.002
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
S20.2 Contusion of thorax	0.002	0.998	0.000
M06.32 Rheumatoid nodule (Upper arm)	0.002	0.998	0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
E21.4 Other specified disorders of parathyroid gland	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
I44.3 Other and unspecified atrioventricular block	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
L56.4 Polymorphous light eruption	0.002	0.998	0.000
L56.3 Solar urticaria	0.002	0.998	0.000
L56.2 Photocontact dermatitis [berloque dermatitis]	0.002	0.998	0.000
L56.1 Drug photoallergic response	0.002	0.998	0.000
L56.0 Drug phototoxic response	0.002	0.998	0.000
C44.6 Skin of upper limb, including shoulder	0.002	0.998	0.000
S62.3 Fracture of other metacarpal bone	0.002	0.998	0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.000	0.998	0.002
L59.9 Disorder of skin and subcutaneous tissue related to radiation, unspecified	0.002	0.998	0.000
L59.0 Erythema ab igne [dermatitis ab igne]	0.002	0.998	0.000
L60.0 Ingrowing nail	0.000	0.998	0.002
M06.8 Other specified rheumatoid arthritis	0.002	0.998	0.000
M06.2 Rheumatoid bursitis	0.002	0.998	0.000
M06.1 Adult-onset Still's disease	0.002	0.998	0.000
R23.8 Other and unspecified skin changes	0.002	0.998	0.000
K65.9 Peritonitis, unspecified	0.000	0.998	0.002
Z99.9 Dependence on unspecified enabling machine and device	0.000	0.998	0.002
Z99.4 Dependence on artificial heart	0.000	0.998	0.002
Z99.0 Dependence on aspirator	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
J40 Bronchitis, not specified as acute or chronic	0.000	0.998	0.002
M06.48 Inflammatory polyarthropathy (Other)	0.002	0.998	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.002	0.998	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.002	0.998	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.002	0.998	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.002	0.998	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.002	0.998	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.002	0.998	0.000
L55.9 Sunburn, unspecified	0.002	0.998	0.000
L55.8 Other sunburn	0.002	0.998	0.000
L55.2 Sunburn of third degree	0.002	0.998	0.000
L55.1 Sunburn of second degree	0.002	0.998	0.000
L55.0 Sunburn of first degree	0.002	0.998	0.000
L58.9 Radiodermatitis, unspecified	0.002	0.998	0.000
L58.1 Chronic radiodermatitis	0.002	0.998	0.000
L58.0 Acute radiodermatitis	0.002	0.998	0.000
Y43.4 Immunosuppressive agents	0.000	0.998	0.002
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
F01.9 Vascular dementia, unspecified	0.002	0.998	0.000
M06.39 Rheumatoid nodule (Site unspecified)	0.002	0.998	0.000
M06.38 Rheumatoid nodule (Other)	0.002	0.998	0.000
M06.36 Rheumatoid nodule (Lower leg)	0.002	0.998	0.000
M06.35 Rheumatoid nodule (Pelvic region and thigh)	0.002	0.998	0.000
M06.33 Rheumatoid nodule (Forearm)	0.002	0.998	0.000
M06.31 Rheumatoid nodule (Shoulder region)	0.002	0.998	0.000
M06.30 Rheumatoid nodule (Multiple sites)	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
S62.31 Fracture of other metacarpal bone (open)	0.002	0.998	0.000
A69.9 Spirochaetal infection, unspecified	0.002	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.001
K58.9 Irritable bowel syndrome without diarrhoea	0.002	0.998	0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.002	0.998	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.002	0.998	0.000
M06.19 Adult-onset Still's disease (Site unspecified)	0.002	0.998	0.000
M06.18 Adult-onset Still's disease (Other)	0.002	0.998	0.000
M06.17 Adult-onset Still's disease (Ankle and foot)	0.002	0.998	0.000
M06.16 Adult-onset Still's disease (Lower leg)	0.002	0.998	0.000
M06.15 Adult-onset Still's disease (Pelvic region and thigh)	0.002	0.998	0.000
M06.14 Adult-onset Still's disease (Hand)	0.002	0.998	0.000
M06.13 Adult-onset Still's disease (Forearm)	0.002	0.998	0.000
M06.12 Adult-onset Still's disease (Upper arm)	0.002	0.998	0.000
M06.11 Adult-onset Still's disease (Shoulder region)	0.002	0.998	0.000
M06.10 Adult-onset Still's disease (Multiple sites)	0.002	0.998	0.000
M06.29 Rheumatoid bursitis (Site unspecified)	0.002	0.998	0.000
M06.28 Rheumatoid bursitis (Other)	0.002	0.998	0.000
M06.27 Rheumatoid bursitis (Ankle and foot)	0.002	0.998	0.000
M06.26 Rheumatoid bursitis (Lower leg)	0.002	0.998	0.000
M06.25 Rheumatoid bursitis (Pelvic region and thigh)	0.002	0.998	0.000
M06.24 Rheumatoid bursitis (Hand)	0.002	0.998	0.000
M06.23 Rheumatoid bursitis (Forearm)	0.002	0.998	0.000
M06.22 Rheumatoid bursitis (Upper arm)	0.002	0.998	0.000
M06.21 Rheumatoid bursitis (Shoulder region)	0.002	0.998	0.000
M06.20 Rheumatoid bursitis (Multiple sites)	0.002	0.998	0.000
M06.89 Other specified rheumatoid arthritis (Site unspecified)	0.002	0.998	0.000
M06.88 Other specified rheumatoid arthritis (Other)	0.002	0.998	0.000
M06.87 Other specified rheumatoid arthritis (Ankle and foot)	0.002	0.998	0.000
M06.86 Other specified rheumatoid arthritis (Lower leg)	0.002	0.998	0.000
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)	0.002	0.998	0.000
M06.84 Other specified rheumatoid arthritis (Hand)	0.002	0.998	0.000
M06.83 Other specified rheumatoid arthritis (Forearm)	0.002	0.998	0.000
M06.82 Other specified rheumatoid arthritis (Upper arm)	0.002	0.998	0.000
M06.81 Other specified rheumatoid arthritis (Shoulder region)	0.002	0.998	0.000
M06.80 Other specified rheumatoid arthritis (Multiple sites)	0.002	0.998	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.998	0.002
Z99.8 Dependence on other enabling machines and devices	0.000	0.998	0.002
F01 Vascular dementia	0.002	0.998	0.000
M06.37 Rheumatoid nodule (Ankle and foot)	0.001	0.998	0.000
D86.0 Sarcoidosis of lung	0.000	0.998	0.002
V93.9 Unspecified watercraft	0.002	0.998	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.998	0.000
F02.2 Dementia in Huntington's disease	0.001	0.998	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.001	0.998	0.000
M25.86 Other specified joint disorders (Lower leg)	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.001	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002
K11.6 Mucocele of salivary gland	0.002	0.998	0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation	0.002	0.998	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.002	0.998	0.000
K11.3 Abscess of salivary gland	0.002	0.998	0.000
T01.2 Open wounds involving multiple regions of upper limb(s)	0.002	0.998	0.000
D73.0 Hyposplenism	0.002	0.998	0.000
T13.1 Open wound of lower limb, level unspecified	0.001	0.998	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
F01.8 Other vascular dementia	0.001	0.998	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.001	0.998	0.000
F01.2 Subcortical vascular dementia	0.001	0.998	0.000
F01.1 Multi-infarct dementia	0.001	0.998	0.000
F01.0 Vascular dementia of acute onset	0.001	0.998	0.000
H73.8 Other specified disorders of tympanic membrane	0.002	0.998	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.998	0.002
M06.0 Seronegative rheumatoid arthritis	0.001	0.998	0.000
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.001
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.001
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.001	0.998	0.000
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.001	0.998	0.000
Q61.0 Congenital single renal cyst	0.001	0.998	0.000
F00 Dementia in Alzheimer's disease	0.001	0.998	0.000
I31.9 Disease of pericardium, unspecified	0.001	0.999	0.000
K58.0 Irritable bowel syndrome with diarrhoea	0.001	0.999	0.000
K91.3 Postoperative intestinal obstruction	0.000	0.999	0.001
N97.9 Female infertility, unspecified	0.001	0.999	0.000
B07 Viral warts	0.000	0.999	0.001
S62.60 Fracture of other finger (closed)	0.001	0.999	0.000
D68.9 Coagulation defect, unspecified	0.000	0.999	0.001
S81.9 Open wound of lower leg, part unspecified	0.001	0.999	0.000
T13 Other injuries of lower limb, level unspecified	0.001	0.999	0.000
A49.8 Other bacterial infections of unspecified site	0.000	0.999	0.001
D68.0 Von Willebrand's disease	0.000	0.999	0.001
M20.5 Other deformities of toe(s) (acquired)	0.000	0.999	0.001
F09 Unspecified organic or symptomatic mental disorder	0.001	0.999	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.001	0.999	0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.999	0.001
C43.6 Malignant melanoma of upper limb, including shoulder	0.000	0.999	0.001
D86.9 Sarcoidosis, unspecified	0.000	0.999	0.001
I12.9 Hypertensive renal disease without renal failure	0.000	0.999	0.001
N17.9 Acute renal failure, unspecified	0.000	0.999	0.001
R23.0 Cyanosis	0.001	0.999	0.000
S02.30 Fracture of orbital floor (closed)	0.000	0.999	0.001
I44.1 Atrioventricular block, second degree	0.001	0.999	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
K11.1 Hypertrophy of salivary gland	0.001	0.999	0.000
K25.3 Acute without haemorrhage or perforation	0.000	0.999	0.001
D68 Other coagulation defects	0.000	0.999	0.001
A49.9 Bacterial infection, unspecified	0.000	0.999	0.001
D10.5 Other parts of oropharynx	0.001	0.999	0.000
M06.08 Seronegative rheumatoid arthritis (Other)	0.001	0.999	0.000
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)	0.001	0.999	0.000
M06.06 Seronegative rheumatoid arthritis (Lower leg)	0.001	0.999	0.000
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)	0.001	0.999	0.000
M06.04 Seronegative rheumatoid arthritis (Hand)	0.001	0.999	0.000
M06.03 Seronegative rheumatoid arthritis (Forearm)	0.001	0.999	0.000
M06.02 Seronegative rheumatoid arthritis (Upper arm)	0.001	0.999	0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)	0.001	0.999	0.000
D68.2 Hereditary deficiency of other clotting factors	0.000	0.999	0.001
F00.1 Dementia in Alzheimer's disease with late onset	0.001	0.999	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.001	0.999	0.000
H26.1 Traumatic cataract	0.000	0.999	0.001
J94.8 Other specified pleural conditions	0.000	0.999	0.001
M11.96 Crystal arthropathy, unspecified (Lower leg)	0.001	0.999	0.000
D68.6 Other Thrombophilia	0.000	0.999	0.001
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.999	0.001
T13.9 Unspecified injury of lower limb, level unspecified	0.001	0.999	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.001	0.999	0.000
T13.6 Traumatic amputation of lower limb, level unspecified	0.001	0.999	0.000
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.001	0.999	0.000
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.001	0.999	0.000
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.001	0.999	0.000
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.001	0.999	0.000
Q85 Phakomatoses, not elsewhere classified	0.001	0.999	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.999	0.001
T01.8 Open wounds involving other combinations of body regions	0.001	0.999	0.000
S42.20 Fracture of upper end of humerus (closed)	0.000	0.999	0.001
B08.1 Molluscum contagiosum	0.000	0.999	0.001
D12.3 Transverse colon	0.000	0.999	0.001
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.001	0.999	0.000
F07.1 Postencephalitic syndrome	0.001	0.999	0.000
F07.0 Organic personality disorder	0.001	0.999	0.000
I44 Atrioventricular and left bundle-branch block	0.001	0.999	0.000
D68.4 Acquired coagulation factor deficiency	0.000	0.999	0.001
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
R41.2 Retrograde amnesia	0.000	0.999	0.001
T88.7 Unspecified adverse effect of drug or medicament	0.000	0.999	0.001
T01 Open wounds involving multiple body regions	0.001	0.999	0.000
K11.2 Sialoadenitis	0.001	0.999	0.000
F07.2 Postconcussional syndrome	0.001	0.999	0.000
G70.0 Myasthenia gravis	0.001	0.999	0.000
I12 Hypertensive renal disease	0.000	0.999	0.001
M12.39 Palindromic rheumatism (Site unspecified)	0.001	0.999	0.000
B00.9 Herpesviral infection, unspecified	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.000	0.999	0.001
Q82.8 Other specified congenital malformations of skin	0.001	0.999	0.000
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
R23 Other skin changes	0.001	0.999	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.001	0.999	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.999	0.000
H26 Other cataract	0.000	0.999	0.001
K58 Irritable bowel syndrome	0.001	0.999	0.000
V93 Accident on board watercraft without accident to watercraft, not causing drowning and submersion	0.001	0.999	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.001	0.999	0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)	0.001	0.999	0.000
S42.30 Fracture of shaft of humerus (closed)	0.000	0.999	0.001
I44.5 Left posterior fascicular block	0.001	0.999	0.000
I44.4 Left anterior fascicular block	0.001	0.999	0.000
K25.4 Chronic or unspecified with haemorrhage	0.000	0.999	0.001
O73.0 Retained placenta, without haemorrhage	0.001	0.999	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.001	0.999	0.000
T01.9 Multiple open wounds, unspecified	0.001	0.999	0.000
T01.6 Open wounds involving multiple regions of upper limb(s) with lower limb(s)	0.001	0.999	0.000
T01.3 Open wounds involving multiple regions of lower limb(s)	0.001	0.999	0.000
T01.1 Open wounds involving thorax with abdomen, lower back and pelvis	0.001	0.999	0.000
T01.0 Open wounds involving head with neck	0.001	0.999	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
K11 Diseases of salivary glands	0.001	0.999	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.999	0.001
I27.0 Primary pulmonary hypertension	0.000	0.999	0.001
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.001	0.999	0.000
D10.0 Lip	0.001	0.999	0.000
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.001	0.999	0.000
M48.5 Collapsed vertebra, not elsewhere classified	0.001	0.999	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.999	0.001
H26.3 Drug-induced cataract	0.000	0.999	0.001
V93.3 Other powered watercraft	0.001	0.999	0.000
V93.8 Other unpowered watercraft	0.001	0.999	0.000
V93.7 Water-skis	0.001	0.999	0.000
V93.6 Inflatable craft (nonpowered)	0.001	0.999	0.000
V93.5 Canoe or kayak	0.001	0.999	0.000
V93.4 Sailboat	0.001	0.999	0.000
V93.2 Fishing boat	0.001	0.999	0.000
V93.1 Passenger ship	0.001	0.999	0.000
V93.0 Merchant ship	0.001	0.999	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.000	0.999	0.001
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.001	0.999	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.001	0.999	0.000
F06.5 Organic dissociative disorder	0.001	0.999	0.000
F06.4 Organic anxiety disorder	0.001	0.999	0.000
F06.3 Organic mood [affective] disorders	0.001	0.999	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.001	0.999	0.000
F06.1 Organic catatonic disorder	0.001	0.999	0.000
F06.0 Organic hallucinosis	0.001	0.999	0.000
K11.7 Disturbances of salivary secretion	0.001	0.999	0.000
K11.4 Fistula of salivary gland	0.001	0.999	0.000
K11.0 Atrophy of salivary gland	0.001	0.999	0.000
L50.9 Urticaria, unspecified	0.001	0.999	0.000
O69.0 Labour and delivery complicated by prolapse of cord	0.001	0.999	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.001	0.999	0.000
S02.3 Fracture of orbital floor	0.000	0.999	0.001
X23.0 Home	0.001	0.999	0.000
Z51.4 Preparatory care for treatment, not elsewhere classified	0.001	0.999	0.000
D10 Benign neoplasm of mouth and pharynx	0.001	0.999	0.000
D86 Sarcoidosis	0.000	0.999	0.001
K25 Gastric ulcer	0.000	0.999	0.001
S20 Superficial injury of thorax	0.001	0.999	0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)	0.001	0.999	0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.001	0.999	0.000
D68.1 Hereditary factor XI deficiency	0.000	0.999	0.001
G12.2 Motor neuron disease	0.001	0.999	0.000
G93.8 Other specified disorders of brain	0.001	0.999	0.000
H26.8 Other specified cataract	0.000	0.999	0.001
N70.9 Salpingitis and oophoritis, unspecified	0.001	0.999	0.000
Q66.8 Other congenital deformities of feet	0.000	0.999	0.001
R23.1 Pallor	0.001	0.999	0.000
T00.9 Multiple superficial injuries, unspecified	0.001	0.999	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.001	0.999	0.000
A49 Bacterial infection of unspecified site	0.000	0.999	0.001
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)	0.001	0.999	0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.001	0.999	0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.001	0.999	0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)	0.001	0.999	0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.001	0.999	0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.001	0.999	0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.001	0.999	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.001	0.999	0.000
A49.1 Streptococcal infection, unspecified	0.000	0.999	0.001
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters	0.000	0.999	0.001
R23.2 Flushing	0.001	0.999	0.000
R45.0 Nervousness	0.001	0.999	0.000
W23.2 School, other institution and public administrative area	0.001	0.999	0.000
A69 Other spirochaetal infections	0.001	0.999	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.999	0.001
T02.40 Fractures involving multiple regions of both upper limbs (closed)	0.001	0.999	0.000
V93.31 Accident on board watercraft without accident to watercraft, not causing drowning and submersion; other powered watercraft; while engaged in leisure activity	0.001	0.999	0.000
D10.9 Pharynx, unspecified	0.001	0.999	0.000
D10.7 Hypopharynx	0.001	0.999	0.000
D10.6 Nasopharynx	0.001	0.999	0.000
D10.4 Tonsil	0.001	0.999	0.000
D10.2 Floor of mouth	0.001	0.999	0.000
D86.3 Sarcoidosis of skin	0.000	0.999	0.001
G41.9 Status epilepticus, unspecified	0.001	0.999	0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation	0.000	0.999	0.001
K25.5 Chronic or unspecified with perforation	0.000	0.999	0.001
K25.2 Acute with both haemorrhage and perforation	0.000	0.999	0.001
K25.1 Acute with perforation	0.000	0.999	0.001
M11.9 Crystal arthropathy, unspecified	0.001	0.999	0.000
S20.7 Multiple superficial injuries of thorax	0.001	0.999	0.000
S20.4 Other superficial injuries of back wall of thorax	0.001	0.999	0.000
S20.1 Other and unspecified superficial injuries of breast	0.001	0.999	0.000
S20.0 Contusion of breast	0.001	0.999	0.000
S62.6 Fracture of other finger	0.001	0.999	0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.000	0.999	0.001
A49.3 Mycoplasma infection, unspecified	0.000	0.999	0.001
A49.2 Haemophilus influenzae infection, unspecified	0.000	0.999	0.001
A63.0 Anogenital (venereal) warts	0.001	0.999	0.000
M12.3 Palindromic rheumatism	0.001	0.999	0.000
Q82.5 Congenital nonneoplastic naevus	0.001	0.999	0.000
W18.3 Sports and athletics area	0.000	0.999	0.001
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.001	0.999	0.000
Q82 Other congenital malformations of skin	0.001	0.999	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.001	0.999	0.000
M11.99 Crystal arthropathy, unspecified (Site unspecified)	0.001	0.999	0.000
M11.98 Crystal arthropathy, unspecified (Other)	0.001	0.999	0.000
M11.97 Crystal arthropathy, unspecified (Ankle and foot)	0.001	0.999	0.000
M11.95 Crystal arthropathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M11.94 Crystal arthropathy, unspecified (Hand)	0.001	0.999	0.000
M11.93 Crystal arthropathy, unspecified (Forearm)	0.001	0.999	0.000
M11.92 Crystal arthropathy, unspecified (Upper arm)	0.001	0.999	0.000
M11.91 Crystal arthropathy, unspecified (Shoulder region)	0.001	0.999	0.000
M11.90 Crystal arthropathy, unspecified (Multiple sites)	0.001	0.999	0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.999	0.001
M25.88 Other specified joint disorders (Other)	0.001	0.999	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.001	0.999	0.000
A69.8 Other specified spirochaetal infections	0.001	0.999	0.000
A69.1 Other Vincent's infections	0.001	0.999	0.000
A69.0 Necrotising ulcerative stomatitis	0.001	0.999	0.000
B08.8 Other specified viral infections characterised by skin and mucous membrane lesions	0.000	0.999	0.001
B08.5 Enteroviral vesicular pharyngitis	0.000	0.999	0.001
B08.4 Enteroviral vesicular stomatitis with exanthem	0.000	0.999	0.001
B08.3 Erythema infectiosum [fifth disease]	0.000	0.999	0.001
B08.2 Exanthema subitum [sixth disease]	0.000	0.999	0.001
B08.0 Other orthopoxvirus infections	0.000	0.999	0.001
G62.8 Other specified polyneuropathies	0.000	0.999	0.001
H74.0 Tympanosclerosis	0.001	0.999	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.001	0.999	0.000
O69.8 Labour and delivery complicated by other cord complications	0.001	0.999	0.000
R23.4 Changes in skin texture	0.001	0.999	0.000
T00.2 Superficial injuries involving multiple regions of upper limb(s)	0.001	0.999	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.001	0.999	0.000
M12.38 Palindromic rheumatism (Other)	0.001	0.999	0.000
M12.37 Palindromic rheumatism (Ankle and foot)	0.001	0.999	0.000
M12.36 Palindromic rheumatism (Lower leg)	0.001	0.999	0.000
M12.35 Palindromic rheumatism (Pelvic region and thigh)	0.001	0.999	0.000
M12.34 Palindromic rheumatism (Hand)	0.001	0.999	0.000
M12.33 Palindromic rheumatism (Forearm)	0.001	0.999	0.000
M12.32 Palindromic rheumatism (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations