TreeWAS – Variant ID: rs12148477

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K50.9 Crohn's disease, unspecified	0.498	0.502	0.000
K50 Crohn's disease [regional enteritis]	0.493	0.507	0.000
K50.0 Crohn's disease of small intestine	0.478	0.522	0.000
K50.8 Other Crohn's disease	0.467	0.533	0.000
K50.1 Crohn's disease of large intestine	0.434	0.566	0.000
O16 Unspecified maternal hypertension	0.049	0.951	0.000
C77.2 Intra-abdominal lymph nodes	0.033	0.967	0.000
K50-K52 Noninfective enteritis and colitis	0.033	0.967	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.981	0.019
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.982	0.018
Z03.5 Observation for other suspected cardiovascular diseases	0.000	0.982	0.018
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.982	0.018
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.018	0.982	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.983	0.017
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.983	0.016
K21.9 Gastro-oesophageal reflux disease without oesophagitis	0.015	0.985	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.985	0.015
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.986	0.014
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.986	0.014
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.013	0.987	0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension	0.013	0.987	0.000
O15 Eclampsia	0.013	0.987	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.987	0.013
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.987	0.013
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.013	0.987	0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.012	0.988	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.012	0.988	0.000
M84 Disorders of continuity of bone	0.000	0.988	0.012
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.988	0.012
O12.2 Gestational oedema with proteinuria	0.010	0.990	0.000
M84.8 Other disorders of continuity of bone	0.000	0.990	0.010
Z33 Pregnant state, incidental	0.000	0.990	0.010
O12.0 Gestational oedema	0.010	0.990	0.000
O15.9 Eclampsia, unspecified as to time period	0.009	0.990	0.000
O15.2 Eclampsia in the puerperium	0.009	0.990	0.000
O15.1 Eclampsia in labour	0.009	0.990	0.000
O15.0 Eclampsia in pregnancy	0.009	0.990	0.000
O10.9 Unspecified pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O10.4 Pre-existing secondary hypertension complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O10.3 Pre-existing hypertensive heart and renal disease complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O10.2 Pre-existing hypertensive renal disease complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O10.1 Pre-existing hypertensive heart disease complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
O14.1 Severe preeclampsia	0.009	0.991	0.000
M84.0 Malunion of fracture	0.000	0.991	0.009
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.009	0.991	0.000
M84.3 Stress fracture, not elsewhere classified	0.000	0.991	0.009
O14.2 HELLP syndrome	0.009	0.991	0.000
O12.1 Gestational proteinuria	0.009	0.991	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.991	0.009
M84.9 Disorder of continuity of bone, unspecified	0.000	0.991	0.009
M84.2 Delayed union of fracture	0.000	0.991	0.008
O14.9 Preeclampsia, unspecified	0.008	0.992	0.000
M84.4 Pathological fracture, not elsewhere classified	0.000	0.992	0.008
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.992	0.008
O14.0 Moderate preeclampsia	0.008	0.992	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.993	0.007
M84.88 Other disorders of continuity of bone (Other)	0.000	0.993	0.007
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.993	0.007
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.993	0.007
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.993	0.007
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.993	0.007
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.993	0.007
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.993	0.007
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.993	0.007
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.993	0.007
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.993	0.007
M84.02 Malunion of fracture (Upper arm)	0.000	0.993	0.007
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.993	0.007
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.993	0.007
M84.09 Malunion of fracture (Site unspecified)	0.000	0.993	0.007
M84.08 Malunion of fracture (Other)	0.000	0.993	0.007
M84.00 Malunion of fracture (Multiple sites)	0.000	0.993	0.007
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.993	0.007
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.993	0.007
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.993	0.007
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.993	0.007
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.993	0.007
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.993	0.007
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.993	0.007
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.993	0.007
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.993	0.007
M84.01 Malunion of fracture (Shoulder region)	0.000	0.993	0.006
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.993	0.006
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.993	0.006
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.993	0.006
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.993	0.006
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.993	0.006
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.993	0.006
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.993	0.006
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.993	0.006
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.993	0.006
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.993	0.006
M84.06 Malunion of fracture (Lower leg)	0.000	0.994	0.006
M84.04 Malunion of fracture (Hand)	0.000	0.994	0.006
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.994	0.006
M84.28 Delayed union of fracture (Other)	0.000	0.994	0.006
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.994	0.006
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.994	0.006
M84.24 Delayed union of fracture (Hand)	0.000	0.994	0.006
M84.23 Delayed union of fracture (Forearm)	0.000	0.994	0.006
M84.22 Delayed union of fracture (Upper arm)	0.000	0.994	0.006
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.994	0.006
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.994	0.006
K55.2 Angiodysplasia of colon	0.000	0.994	0.006
M84.26 Delayed union of fracture (Lower leg)	0.000	0.994	0.006
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.994	0.006
M84.03 Malunion of fracture (Forearm)	0.000	0.994	0.006
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.994	0.006
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.994	0.006
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.994	0.006
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.994	0.006
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.994	0.006
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.994	0.006
K52 Other non-infective gastro-enteritis and colitis	0.006	0.994	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.994	0.006
K02.9 Dental caries, unspecified	0.000	0.995	0.005
H18.8 Other specified disorders of cornea	0.005	0.995	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.005	0.995	0.000
K52.1 Toxic gastro-enteritis and colitis	0.005	0.995	0.000
H18.4 Corneal degeneration	0.005	0.995	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.005	0.995	0.000
H18 Other disorders of cornea	0.005	0.995	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
Z88.6 Personal history of allergy to analgesic agent	0.000	0.995	0.005
E83.3 Disorders of phosphorus metabolism	0.005	0.995	0.000
O03.9 Complete or unspecified, without complication	0.000	0.995	0.005
R52.1 Chronic intractable pain	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.004	0.996	0.000
M54.16 Radiculopathy (Lumbar region)	0.004	0.996	0.000
G35 Multiple sclerosis	0.000	0.996	0.004
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.996	0.004
O26.9 Pregnancy-related condition, unspecified	0.000	0.996	0.004
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
M89.88 Other specified disorders of bone (Other)	0.000	0.996	0.004
M89.8 Other specified disorders of bone	0.000	0.996	0.004
D12.7 Rectosigmoid junction	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.000	0.996	0.004
H18.3 Changes in corneal membranes	0.004	0.996	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.004	0.996	0.000
S40.0 Contusion of shoulder and upper arm	0.004	0.996	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.996	0.004
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.000	0.996	0.004
Z39.1 Care and examination of lactating mother	0.000	0.996	0.004
H18.7 Other corneal deformities	0.003	0.996	0.000
H18.5 Hereditary corneal dystrophies	0.004	0.996	0.000
M89.84 Other specified disorders of bone (Hand)	0.000	0.996	0.003
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.997	0.003
H18.2 Other corneal oedema	0.003	0.997	0.000
F33.9 Recurrent depressive disorder, unspecified	0.003	0.997	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.000	0.997	0.003
H18.1 Bullous keratopathy	0.003	0.997	0.000
Z39.2 Routine postpartum follow-up	0.000	0.997	0.003
G35-G37 Demyelinating diseases of the central nervous system	0.000	0.997	0.003
C71.9 Brain, unspecified	0.003	0.997	0.000
M80-M85 Disorders of bone density and structure	0.000	0.997	0.003
G37.8 Other specified demyelinating diseases of central nervous system	0.000	0.997	0.003
K52.8 Other specified non-infective gastro-enteritis and colitis	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
E86 Volume depletion	0.003	0.997	0.000
K52.3 Indeterminate colitis	0.003	0.997	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.000	0.997	0.003
M89.83 Other specified disorders of bone (Forearm)	0.000	0.997	0.003
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.997	0.003
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.997	0.003
K08.9 Disorder of teeth and supporting structures, unspecified	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.000	0.997	0.003
G37.4 Subacute necrotising myelitis	0.000	0.997	0.003
G37.2 Central pontine myelinolysis	0.000	0.997	0.003
G37.1 Central demyelination of corpus callosum	0.000	0.997	0.003
G37.0 Diffuse sclerosis	0.000	0.997	0.003
Z39 Postpartum care and examination	0.000	0.997	0.003
K02 Dental caries	0.000	0.997	0.003
M89.81 Other specified disorders of bone (Shoulder region)	0.000	0.997	0.003
M80 Osteoporosis with pathological fracture	0.000	0.997	0.003
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.997	0.003
K02.8 Other dental caries	0.000	0.997	0.003
M89.55 Osteolysis (Pelvic region and thigh)	0.000	0.997	0.003
G36 Other acute disseminated demyelination	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.997	0.003
M83 Adult osteomalacia	0.000	0.997	0.002
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.997	0.002
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.003	0.997	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.002	0.997	0.000
M85.8 Other specified disorders of bone density and structure	0.000	0.997	0.002
K21 Gastro-oesophageal reflux disease	0.003	0.997	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.000	0.997	0.003
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.998	0.002
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
C49.2 Connective and soft tissue of lower limb, including hip	0.002	0.998	0.000
C49.0 Connective and soft tissue of head, face and neck	0.002	0.998	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.998	0.002
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.000	0.998	0.002
M89.5 Osteolysis	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
M85 Other disorders of bone density and structure	0.000	0.998	0.002
G59.0 Diabetic mononeuropathy	0.002	0.998	0.000
K02.5 Caries with pulp exposure	0.000	0.998	0.002
K02.4 Odontoclasia	0.000	0.998	0.002
K02.3 Arrested dental caries	0.000	0.998	0.002
K02.2 Caries of cementum	0.000	0.998	0.002
K02.0 Caries limited to enamel	0.000	0.998	0.002
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.998	0.002
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.998	0.002
I60.9 Subarachnoid haemorrhage, unspecified	0.002	0.998	0.000
K02.1 Caries of dentin	0.000	0.998	0.002
M79.79 Fibromyalgia (Site unspecified)	0.000	0.998	0.002
F33.0 Recurrent depressive disorder, current episode mild	0.002	0.998	0.000
H18.6 Keratoconus	0.002	0.998	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.002	0.998	0.000
D25.2 Subserosal leiomyoma of uterus	0.000	0.998	0.002
G44.0 Cluster headache syndrome	0.002	0.998	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.998	0.002
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.998	0.002
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.998	0.002
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.000	0.998	0.002
M89 Other disorders of bone	0.000	0.998	0.002
C71.2 Temporal lobe	0.002	0.998	0.000
M81 Osteoporosis without pathological fracture	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
G36.9 Acute disseminated demyelination, unspecified	0.000	0.998	0.002
G36.8 Other specified acute disseminated demyelination	0.000	0.998	0.002
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.000	0.998	0.002
G36.0 Neuromyelitis optica [Devic]	0.000	0.998	0.002
D76.3 Other histiocytosis syndromes	0.002	0.998	0.000
Z83.3 Family history of diabetes mellitus	0.002	0.998	0.000
M83.8 Other adult osteomalacia	0.000	0.998	0.002
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
M83.9 Adult osteomalacia, unspecified	0.000	0.998	0.002
M83.5 Other drug-induced osteomalacia in adults	0.000	0.998	0.002
M83.4 Aluminum bone disease	0.000	0.998	0.002
M83.3 Adult osteomalacia due to malnutrition	0.000	0.998	0.002
M83.2 Adult osteomalacia due to malabsorption	0.000	0.998	0.002
M83.1 Senile osteomalacia	0.000	0.998	0.002
M83.0 Puerperal osteomalacia	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.998	0.002
C77.4 Inguinal and lower limb lymph nodes	0.002	0.998	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.998	0.002
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.998	0.002
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.998	0.002
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.002	0.998	0.000
M81.4 Drug-induced osteoporosis	0.000	0.998	0.002
M89.0 Algoneurodystrophy	0.000	0.998	0.002
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.002	0.998	0.000
E83 Disorders of mineral metabolism	0.002	0.998	0.000
F33 Recurrent depressive disorder	0.002	0.998	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
I38 Endocarditis, valve unspecified	0.002	0.998	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.8 Other osteoporosis with pathological fracture	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.000	0.998	0.002
M89.37 Hypertrophy of bone (Ankle and foot)	0.000	0.998	0.002
O61.0 Failed medical induction of labour	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.000	0.998	0.002
M89.58 Osteolysis (Other)	0.000	0.998	0.002
M89.57 Osteolysis (Ankle and foot)	0.000	0.998	0.002
M89.56 Osteolysis (Lower leg)	0.000	0.998	0.002
M89.54 Osteolysis (Hand)	0.000	0.998	0.002
M89.53 Osteolysis (Forearm)	0.000	0.998	0.002
M89.52 Osteolysis (Upper arm)	0.000	0.998	0.002
M89.51 Osteolysis (Shoulder region)	0.000	0.998	0.002
M89.50 Osteolysis (Multiple sites)	0.000	0.998	0.002
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
M85.5 Aneurysmal bone cyst	0.000	0.998	0.002
M85.4 Solitary bone cyst	0.000	0.998	0.002
M85.3 Osteitis condensans	0.000	0.998	0.002
M85.1 Skeletal fluorosis	0.000	0.998	0.002
S40.8 Other superficial injuries of shoulder and upper arm	0.002	0.998	0.000
M20.6 Acquired deformity of toe(s), unspecified	0.002	0.998	0.000
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.998	0.002
H60.1 Cellulitis of external ear	0.000	0.998	0.002
M89.06 Algoneurodystrophy (Lower leg)	0.000	0.998	0.002
C49.9 Connective and soft tissue, unspecified	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
H15.1 Episcleritis	0.002	0.998	0.000
M85.9 Disorder of bone density and structure, unspecified	0.000	0.998	0.002
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.998	0.002
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.998	0.002
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.998	0.002
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.000	0.998	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.000	0.998	0.002
M89.2 Other disorders of bone development and growth	0.000	0.998	0.002
M89.1 Epiphyseal arrest	0.000	0.998	0.002
M89.04 Algoneurodystrophy (Hand)	0.000	0.998	0.002
M81.8 Other osteoporosis	0.000	0.998	0.002
M81.6 Localised osteoporosis [Lequesne]	0.000	0.998	0.002
M81.5 Idiopathic osteoporosis	0.000	0.998	0.002
M81.1 Postoophorectomy osteoporosis	0.000	0.998	0.002
E83.1 Disorders of iron metabolism	0.002	0.998	0.000
I45.6 Preexcitation syndrome	0.002	0.998	0.000
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.002	0.998	0.000
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.001
H16 Keratitis	0.002	0.998	0.000
Z57 Occupational exposure to risk-factors	0.000	0.998	0.002
H16.8 Other keratitis	0.002	0.998	0.000
M81.2 Osteoporosis of disuse	0.000	0.998	0.002
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.998	0.002
M83.08 Puerperal osteomalacia (Other)	0.000	0.998	0.002
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.998	0.002
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.998	0.002
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.998	0.002
M83.04 Puerperal osteomalacia (Hand)	0.000	0.998	0.002
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.998	0.002
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.998	0.002
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.998	0.002
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.998	0.002
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.998	0.002
M83.18 Senile osteomalacia (Other)	0.000	0.998	0.002
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.998	0.002
M83.16 Senile osteomalacia (Lower leg)	0.000	0.998	0.002
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.998	0.002
M83.14 Senile osteomalacia (Hand)	0.000	0.998	0.002
M83.13 Senile osteomalacia (Forearm)	0.000	0.998	0.002
M83.12 Senile osteomalacia (Upper arm)	0.000	0.998	0.002
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.998	0.002
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.998	0.002
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.998	0.002
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.998	0.002
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.998	0.002
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.998	0.002
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.998	0.002
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.998	0.002
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.998	0.002
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.998	0.002
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.998	0.002
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.998	0.002
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.998	0.002
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.998	0.002
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.998	0.002
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.998	0.002
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.998	0.002
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.998	0.002
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.998	0.002
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.998	0.002
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.998	0.002
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.998	0.002
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.998	0.002
M83.48 Aluminium bone disease (Other)	0.000	0.998	0.002
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.998	0.002
M83.46 Aluminium bone disease (Lower leg)	0.000	0.998	0.002
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.998	0.002
M83.44 Aluminium bone disease (Hand)	0.000	0.998	0.002
M83.43 Aluminium bone disease (Forearm)	0.000	0.998	0.002
M83.42 Aluminium bone disease (Upper arm)	0.000	0.998	0.002
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.998	0.002
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.998	0.002
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.998	0.002
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.998	0.002
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.998	0.002
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.998	0.002
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.998	0.002
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.998	0.002
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.998	0.002
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.998	0.002
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.998	0.002
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.998	0.002
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.998	0.002
M83.88 Other adult osteomalacia (Other)	0.000	0.998	0.002
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.998	0.002
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.998	0.002
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.998	0.002
M83.84 Other adult osteomalacia (Hand)	0.000	0.998	0.002
M83.83 Other adult osteomalacia (Forearm)	0.000	0.998	0.002
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.998	0.002
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.998	0.002
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.998	0.002
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.998	0.002
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.998	0.002
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.998	0.002
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.998	0.002
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.998	0.002
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.998	0.002
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.998	0.002
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.998	0.002
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.998	0.002
C77.5 Intrapelvic lymph nodes	0.002	0.998	0.000
H16.3 Interstitial and deep keratitis	0.002	0.998	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.998	0.001
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.998	0.001
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.998	0.001
N90.4 Leukoplakia of vulva	0.002	0.998	0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.998	0.002
M81.48 Drug-induced osteoporosis (Other)	0.000	0.998	0.002
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.998	0.002
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.998	0.002
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.998	0.002
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.998	0.002
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.998	0.002
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.998	0.002
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.000	0.998	0.002
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.000	0.998	0.002
M89.02 Algoneurodystrophy (Upper arm)	0.000	0.998	0.002
M89.01 Algoneurodystrophy (Shoulder region)	0.000	0.998	0.002
D30.0 Kidney	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.002
M85.2 Hyperostosis of skull	0.000	0.998	0.001
Z57.3 Occupational exposure to other air contaminants	0.000	0.998	0.002
H15 Disorders of sclera	0.002	0.998	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
C71.7 Brain stem	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.002	0.998	0.000
E83.8 Other disorders of mineral metabolism	0.002	0.998	0.000
E83.2 Disorders of zinc metabolism	0.002	0.998	0.000
E83.0 Disorders of copper metabolism	0.002	0.998	0.000
F33.8 Other recurrent depressive disorders	0.002	0.998	0.000
F33.4 Recurrent depressive disorder, currently in remission	0.002	0.998	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.998	0.002
I60.8 Other subarachnoid haemorrhage	0.002	0.998	0.000
M81.0 Postmenopausal osteoporosis	0.000	0.998	0.002
M89.00 Algoneurodystrophy (Multiple sites)	0.000	0.998	0.002
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.001
C49.6 Connective and soft tissue of trunk, unspecified	0.002	0.998	0.000
C49.5 Connective and soft tissue of pelvis	0.002	0.998	0.000
Z57.8 Occupational exposure to other risk-factors	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.000	0.998	0.002
M89.36 Hypertrophy of bone (Lower leg)	0.000	0.998	0.002
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.000	0.998	0.002
M89.34 Hypertrophy of bone (Hand)	0.000	0.998	0.002
M89.33 Hypertrophy of bone (Forearm)	0.000	0.998	0.002
M89.32 Hypertrophy of bone (Upper arm)	0.000	0.998	0.002
M89.31 Hypertrophy of bone (Shoulder region)	0.000	0.998	0.002
M89.30 Hypertrophy of bone (Multiple sites)	0.000	0.998	0.002
C49.8 Overlapping lesion of connective and soft tissue	0.002	0.998	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.000	0.998	0.002
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
C71.4 Occipital lobe	0.002	0.998	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations